The existing 2D settlement monitoring systems for utility tunnels are heavily reliant on manual interpretation of deformation data and empirical predictionmodels.Consequently,early anomalies(e.g.,minor cracks)are ofte...The existing 2D settlement monitoring systems for utility tunnels are heavily reliant on manual interpretation of deformation data and empirical predictionmodels.Consequently,early anomalies(e.g.,minor cracks)are often misjudged,and warnings lag by about 24 h without automated spatial localization.This study establishes a technical framework for requirements analysis,architectural design,and data-integration protocols.Revit parametric modelling is used to build a 3D tunnel model with structural elements,pipelines and 18 monitoring points(for displacement and joint width).Custom Revit API code integrated real-time sensor data into the BIM platform via an automated pipeline.The system achieved a spatial accuracy of±1 mm in locating deformation hotspots.Notifications are triggered within 10 s of anomaly detection,and the system renders 3D risk propagation paths in real-time.Realtime 3D visualization of risk propagation paths is also facilitated.The efficacy of the solution was validated in a Ningbo utility tunnel project,where it was demonstrated that it eliminates human-dependent judgment errors and reduces warning latency by 99.9%compared to conventional methods.The BIM-IoT integrated approach,which enables millimetre-level precision in risk identification and near-instantaneous response,establishes a new paradigm for intelligent infrastructure safety management.展开更多
The effective early warning of surrounding rock mass deformation is crucial in geotechnical engineering for ensuring the safety and stability of underground constructions.This study introduces a novel risk early warni...The effective early warning of surrounding rock mass deformation is crucial in geotechnical engineering for ensuring the safety and stability of underground constructions.This study introduces a novel risk early warning model based on multi-parameter fuzzy comprehensive evaluation,which quantitatively assesses the risk state of the surrounding rock mass.The microseismic(MS)monitoring system is set up for the underground powerhouse.The spatial and temporal distribution of MS events and the frequency characteristics of MS signals are analyzed during the top arch excavation.The early warning indices for characterizing MS spatial aggregation and frequency-energy dispersion are proposed based on the octree theory to assess the deformation of the surrounding rock mass.The risk warning model for the surrounding rock mass in underground engineering is developed through the integration of the formulated index and the frequency characteristics of MS signals.The results indicate that the multiparameter fuzzy comprehensive assessment model can achieve three-dimensional visualization of risk warnings for the surrounding rock mass.The quantitative results regarding warning time and potential deformation areas are highly consistent with the characteristics of MS precursors.These research results can provide an important reference for early warning of surrounding rock mass risk in similar underground projects.展开更多
In the field of rock engineering,the influence of water is a dynamic process that exhibits varying effects over time and across different locations.To further understand how water influences the mechanical properties ...In the field of rock engineering,the influence of water is a dynamic process that exhibits varying effects over time and across different locations.To further understand how water influences the mechanical properties and acoustic emission(AE)behavior of rocks,this study conducted uniaxial compression experiments on sandstones with varying degrees of wetting under both natural conditions and water-chemical environments.In addition,the study combined AE equipment with digital image correlation(DIC)to monitor the entire failure process.Using the sliding window algorithm,the variation in the variance of AE characteristic parameters during the process of sandstone loading to failure is analyzed from the perspective of critical slowing down.This analysis enables the effective identification of the early warning signal before failure.The experimental findings suggest that an increase in wetting height results in a gradual decrease in peak stress,accompanied by a concomitant increase in the percentage of shear cracks.The characteristic parameters,including energy,amplitude,and ringing count,all exhibit critical slowing phenomena.The waveform of AE characteristic parameters of the same sample is similar,and the mutation time of the precursor signal is roughly the same.All signals appear in the irreversible plastic deformation stage of microcrack initiation.The integration of critical slowing down theory and the b-value early warning method facilitates a more comprehensive evaluation of the stability of rock mass,thereby significantly enhancing the efficiency and safety of disaster prevention measures.展开更多
To advance the theoretical understanding,technological development,and field application of electric charge induction for monitoring rock deformation and failure,this study investigates the induced electric charge gen...To advance the theoretical understanding,technological development,and field application of electric charge induction for monitoring rock deformation and failure,this study investigates the induced electric charge generated during the deformation and failure of igneous rocks.The charge originates mainly from a combination of electrical polarization and triboelectric effects.Through laboratory experiments,we analyzed the time-frequency evolution of induced electric charge signals and identified relevant monitoring parameters.An online downhole electric charge induction monitoring system was developed and validated in the field.Experimental results show that the dominant frequency range of induced electric charge signals generated during igneous rock deformation and failure lies between 0 and 23 Hz,and a low-pass finite impulse response(FIR)filter effectively suppresses noise.Optimal sensor distances for monitoring cubic and cylindrical specimens were determined to be 17 mm and 13 mm,respectively.We proposed early warning indicators,including the maximum absolute value of the induced electric charge,the arithmetic mean value,the distribution dispersion coefficient,and the cumulative sum value.In field application,time-domain curves and spatial distribution charts of these warning indicators correspond well with changes in abutment stress ahead of the mining face,offering indirect insights into local stress evolution.This research provides technical and equipment support for the application of electric charge induction technology to monitoring and early warning of coal bursts.展开更多
【选注者言:这是一则“出口转内销”的文章。我在近日的《北京日报》上读到了这篇带“警告性”的短文,不料在Yahoo News里也刊登了英国路透社从北京发出的这则消息,我在网上“冲浪”时,又读该文,觉得别有兴味。我的一个远亲购置了新屋,...【选注者言:这是一则“出口转内销”的文章。我在近日的《北京日报》上读到了这篇带“警告性”的短文,不料在Yahoo News里也刊登了英国路透社从北京发出的这则消息,我在网上“冲浪”时,又读该文,觉得别有兴味。我的一个远亲购置了新屋,以花岗岩石铺地,豪华气派,雍容华贵。在读了最近新华社发的文章后,我的亲戚举家心情沮丧,顿感肺部不适,不知是心理作用,还是真的受到了radioactive gas(放射性气体)的刺激。很快就请人重铺地面,心情和肺部均不再有任何不适。我将本文发给你们,目的是为了让更多的购房者少走弯路,“趋吉避凶”。本文末句把国人的装修归结到spending spree(消费狂热)the government wants to encourage to boost(推进)the economy。给人一种过于牵强的感觉。】展开更多
Iced transmission line galloping poses a significant threat to the safety and reliability of power systems,leading directly to line tripping,disconnections,and power outages.Existing early warning methods of iced tran...Iced transmission line galloping poses a significant threat to the safety and reliability of power systems,leading directly to line tripping,disconnections,and power outages.Existing early warning methods of iced transmission line galloping suffer from issues such as reliance on a single data source,neglect of irregular time series,and lack of attention-based closed-loop feedback,resulting in high rates of missed and false alarms.To address these challenges,we propose an Internet of Things(IoT)empowered early warning method of transmission line galloping that integrates time series data from optical fiber sensing and weather forecast.Initially,the method applies a primary adaptive weighted fusion to the IoT empowered optical fiber real-time sensing data and weather forecast data,followed by a secondary fusion based on a Back Propagation(BP)neural network,and uses the K-medoids algorithm for clustering the fused data.Furthermore,an adaptive irregular time series perception adjustment module is introduced into the traditional Gated Recurrent Unit(GRU)network,and closed-loop feedback based on attentionmechanism is employed to update network parameters through gradient feedback of the loss function,enabling closed-loop training and time series data prediction of the GRU network model.Subsequently,considering various types of prediction data and the duration of icing,an iced transmission line galloping risk coefficient is established,and warnings are categorized based on this coefficient.Finally,using an IoT-driven realistic dataset of iced transmission line galloping,the effectiveness of the proposed method is validated through multi-dimensional simulation scenarios.展开更多
In order to solve the problems of high coupling and poor scalability of the traditional monomer early warning release system architecture,multi-level deployment in a complex network environment will lead to high inves...In order to solve the problems of high coupling and poor scalability of the traditional monomer early warning release system architecture,multi-level deployment in a complex network environment will lead to high investment in software and hardware and cannot achieve intensive multi-level deployment.This paper realizes the goal of system scalability by introducing micro service architecture and technology stack and realizes the goal of resource intensification by introducing the idea of a data forwarding agent.The designed architecture scheme has been practically applied in the“Jiangxi emergency early warning information release system software platform(phase I)project”(hereinafter referred to as“provincial emergency”),which meets the needs of flexible deployment of multi-level applications across meteorological wide area network(WAN),business private network of other commissions,offices,and bureaus,government extranet,Internet and other complex networks,and fully verifies the scientificity and rationality of the scheme.It has achieved the goal of intensive and scalable construction of provincial emergencies under the complex network environment,greatly improved the early warning capacity and communication capacity of emergencies and comprehensive disasters,provided a reliable guarantee for disaster prevention and reduction,and provided a reference for the construction of current and future early warning release system and capacity improvement project.展开更多
BACKGROUND Emphysematous pyelonephritis(EPN)is a life-threatening necrotizing renal parenchyma infection characterized by gas formation due to severe bacterial infection,predominantly affecting diabetic and immunocomp...BACKGROUND Emphysematous pyelonephritis(EPN)is a life-threatening necrotizing renal parenchyma infection characterized by gas formation due to severe bacterial infection,predominantly affecting diabetic and immunocompromised patients.It carries high morbidity and mortality,requiring early diagnosis and timely intervention.Various prognostic scoring systems help in triaging critically ill patients.The National Early Warning Score 2(NEWS 2)scoring system is a widely used physiological assessment tool that evaluates clinical deterioration based on vital parameters,but its standard form lacks specificity for risk stratification in EPN,necessitating modifications to improve treatment decisionmaking and prognostic accuracy in this critical condition.AIM To highlight the need to modify the NEWS 2 score to enable more intense monitoring and better treatment outcomes.METHODS This prospective study was done on all EPN patients admitted to our hospital over the past 12 years.A weighted average risk-stratification index was calculated for each of the three groups,mortality risk was calculated for each of the NEWS 2 scores,and the need for intervention for each of the three groups was calculated.The NEWS 2 score was subsequently modified with 0-6,7-14 and 15-20 scores included in groups 1,2 and 3,respectively.RESULTS A total of 171 patients with EPN were included in the study,with a predominant association with diabetes(90.6%)and a female-to-male ratio of 1.5:1.The combined prognostic scoring of the three groups was 10.7,13.0,and 21.9,respectively(P<0.01).All patients managed conservatively belonged to group 1(P<0.01).Eight patients underwent early nephrectomy,with six from group 3(P<0.01).Overall mortality was 8(4.7%),with seven from group 3(87.5%).The cutoff NEWS 2 score for mortality was identified to be 15,with a sensitivity of 87.5%,specificity of 96.9%,and an overall accuracy rate of 96.5%.The area under the curve to predict mortality based on the NEWS 2 score was 0.98,with a confidence interval of(0.97,1.0)and P<0.001.CONCLUSION Modified NEWS 2(mNEWS 2)score dramatically aids in the appropriate assessment of treatment-related outcomes.MNEWS 2 scores should become the practice standard to reduce the morbidity and mortality associated with this dreaded illness.展开更多
Deep coal-energy mining frequently results in microseismic(MS)events,which may be a precursor to the risk of rockbursts and pose risks to human safety and infrastructure.Therefore,quantitatively predicting the time,en...Deep coal-energy mining frequently results in microseismic(MS)events,which may be a precursor to the risk of rockbursts and pose risks to human safety and infrastructure.Therefore,quantitatively predicting the time,energy,and location(TEL)of future MS events is crucial for understanding and preventing potential catastrophic events.In this study,we introduced the application of spatiotemporal graph convolutional networks(STGCN)to predict the TEL of MS events induced by deep coal-energy mining.Notably,this was the first application of graph convolution networks(GCNs)in the spatiotemporal prediction of MS events.The adjacency matrices of the sensor networks were determined based on the distance between MS sensors,the sensor network graphs we constructed,and GCN was employed to extract the spatiotemporal details of the graphs.The model is simple and versatile.By testing the model with on-site MS monitoring data,our results demonstrated promising efficacy in predicting the TEL of MS events,with the cosine similarity(C)above 0.90 and the mean relative error(MRE)below 0.08.This is critical to improving the safety and operational efficiency of deep coal-energy mining.展开更多
Due to batteries inconsistencies and potential faults in battery management systems,slight overcharging remains a common yet insufficiently understood safety risk,lacking effective warning methods.To illuminate the de...Due to batteries inconsistencies and potential faults in battery management systems,slight overcharging remains a common yet insufficiently understood safety risk,lacking effective warning methods.To illuminate the degradation behavior and failure mechanism of various overcharged states(100%SOC,105%SOC,110%SOC,and 115%SOC),multiple advanced in-situ characterization techniques(accelerating rate calorimeter,electrochemical impedance spectroscopy,ultrasonic scanning,and expansion instrument)were utilized.Additionally,re-overcharge-induced thermal runaway(TR)tests were conducted,with a specific emphasis on the evolution of the expansion force signal.Results indicated significant degradation at 110%SOC including conductivity loss,loss of lithium inventory,and loss of active material accompanied by internal gas generation.These failure behaviors slow down the expansion force rate during reovercharging,reducing the efficacy of active warnings that depend on rate thresholds of expansion force.Specifically,the warning time for 115%SOC battery is only 144 s,which is 740 s shorter than that for fresh battery,and the time to TR is advanced by 9 min.Moreover,the initial self-heating temperature(T1)is reduced by 62.4℃compared to that of fresh battery,reaching only 70.8℃.To address the low safety of overcharged batteries,a passive overcharge warning method utilizing relaxation expansion force was proposed,based on the continued gas generation after stopping charging,leading to a sustained increase in force.Compared to active methods that rely on thresholds of expansion force rate,the passive method can issue warnings 115 s earlier.By combining the passive and active warning methods,guaranteed effective overcharge warning can be issued 863-884 s before TR.This study introduces a novel perspective for enhancing the safety of batteries.展开更多
Coating microdefects and localized corrosion in coating/metal system are inevitable,accelerating the degradation of metal infrastructure.Early evaluating coating microdefects and detecting corrosion sites are urgent y...Coating microdefects and localized corrosion in coating/metal system are inevitable,accelerating the degradation of metal infrastructure.Early evaluating coating microdefects and detecting corrosion sites are urgent yet remain challenge to achieve.Herein,we propose a robust,universal and efficient fluorescence-based strategy for hierarchical warning of coating damage and metal corrosion by introducing the concepts of damage-induced fluorescence enhancement effect(DIE)and ionic-recognition induced quenching effect(RIQ).The coatings with dualresponsiveness for coating defect and steel corrosion are constructed by incorporating synthesized nanoprobes composed of metal organic frameworks(Ni–Zn-MOFs)loaded with Rhodamine B(RhB@MOFs).The initial damage to the coating causes an immediate intensification of fluorescence,while the specific ionic-recognition characteristic of RhB with Fe3t results in an evident fluorescence quenching,enabling the detection of coating damage and corrosion.Importantly,this nanoprobes are insensitive to the coating matrix and exhibit stable corrosion warning capability across various coating systems.Meanwhile,electrochemical investigations indicate that the impedance values of RM/EP maintain above 10^(8)Ωcm^(2)even after 60 days of immersion.Therefore,the incorporation of fluorescent nanoprobes greatly inhibits the intrusion of electrolytes into polymer and improves the corrosion protection performance of the coating.This powerful strategy towards dual-level damage warning provides insights for the development of long-term smart protective materials.展开更多
Enhancing the firefighting protective clothing with exceptional thermal barrier and temperature sensing functions to ensure high fire safety for firefighters has long been anticipated,but it remains a major challenge....Enhancing the firefighting protective clothing with exceptional thermal barrier and temperature sensing functions to ensure high fire safety for firefighters has long been anticipated,but it remains a major challenge.Herein,inspired by the human muscle,an anisotropic fire safety aerogel(ACMCA)with precise self-actuated temperature monitoring performance is developed by combining aramid nanofibers with eicosane/MXene to form an anisotropically oriented conductive network.By combining the two synergies of the negative temperaturedependent thermal conductive eicosane,which induces a high-temperature differential,and directionally ordered MXene that establishes a conductive network along the directional freezing direction.The resultant ACMCA exhibited remarkable thermoelectric properties,with S values reaching 46.78μV K^(−1)andκvalues as low as 0.048 W m^(−1)K^(−1)at room temperature.Moreover,the prepared anisotropic aerogel ACMCA exhibited electrical responsiveness to temperature variations,facilitating its application in intelligent temperature monitoring systems.The designed anisotropic aerogel ACMCA could be incorporated into the firefighting clothing as a thermal barrier layer,demonstrating a wide temperature sensing range(50-400℃)and a rapid response time for early high-temperature alerts(~1.43 s).This work provides novel insights into the design and application of temperature-sensitive anisotropic aramid nanofibers aerogel in firefighting clothing.展开更多
The traditional academic warning methods for students in higher vocational colleges are relatively backward,single,and have many influencing factors,which have a limited effect on improving their learning ability.A da...The traditional academic warning methods for students in higher vocational colleges are relatively backward,single,and have many influencing factors,which have a limited effect on improving their learning ability.A data set was established by collecting academic warning data of students in a certain university.The importance of the school,major,grade,and warning level for the students was analyzed using the Pearson correlation coefficient,random forest variable importance,and permutation importance.It was found that the characteristic of the major has a great impact on the academic warning level.Countermeasures such as dynamic adjustment of majors,reform of cognitive adaptation of courses,full-cycle academic support,and data-driven precise intervention were proposed to provide theoretical support and practical paths for universities to improve the efficiency of academic warning and enhance students’learning ability.展开更多
As oil and gas exploration continues to progress into deeper and unconventional reservoirs,the likelihood of kick risk increases,making kick warning a critical factor in ensuring drilling safety and efficiency.Due to ...As oil and gas exploration continues to progress into deeper and unconventional reservoirs,the likelihood of kick risk increases,making kick warning a critical factor in ensuring drilling safety and efficiency.Due to the scarcity of kick samples,traditional supervised models perform poorly,and significant fluctuations in field data lead to high false alarm rates.This study proposes an unsupervised graph autoencoder(GAE)-based kick warning method,which effectively reduces false alarms by eliminating the influence of field engineer operations and incorporating real-time model updates.The method utilizes the GAE model to process time-series data during drilling,accurately identifying kick risk while overcoming challenges related to small sample sizes and missing features.To further reduce false alarms,the weighted dynamic time warping(WDTW)algorithm is introduced to identify fluctuations in logging data caused by field engineer operations during drilling,with real-time updates applied to prevent normal conditions from being misclassified as kick risk.Experimental results show that the GAE-based kick warning method achieves an accuracy of 92.7%and significantly reduces the false alarm rate.The GAE model continues to operate effectively even under conditions of missing features and issues kick warnings 4 min earlier than field engineers,demonstrating its high sensitivity and robustness.After integrating the WDTW algorithm and real-time updates,the false alarm rate is reduced from 17.3%to 5.6%,further improving the accuracy of kick warnings.The proposed method provides an efficient and reliable approach for kick warning in drilling operations,offering strong practical value and technical support for the intelligent management of future drilling operations.展开更多
The level of ground shaking,as determined by the peak ground acceleration(PGA),can be used to analyze seismic hazard at a certain location and is crucial for constructing earthquake-resistant structures.Predicting the...The level of ground shaking,as determined by the peak ground acceleration(PGA),can be used to analyze seismic hazard at a certain location and is crucial for constructing earthquake-resistant structures.Predicting the PGA immediately after an earthquake occurs allows for the issuing of a warning by an earthquake early warning system.In this study,we propose a deep learning model,ConvMixer,to predict the PGA recorded by weak-motion velocity seismometers in Japan.We use 5-s threecomponent seismograms,from 2 s before until 3 s after the P-wave arrival time of the earthquake.Our dataset comprised more than 50,000 single-station waveforms recorded by 10 seismic stations in the K-NET,Kiki-NET,and Hi-Net networks between 2004 and 2023.The proposed ConvMixer is a patch-based model that extracts global features from input seismic data and predicts the PGA of an earthquake by combining depth and pointwise convolutions.The proposed ConvMixer network had a mean absolute error of 2.143 when applied to the test set and outperformed benchmark deep learning models.In addition,the proposed ConvMixer demonstrated the ability to predict the PGA at the corresponding station site based on 1-second waveforms obtained immediately after the arrival time of the P-wave.展开更多
Clarifying the mechanisms through which coal mining affects groundwater storage(GWS)variations is crucial for water resource conservation and sustainable development.The Ordos Mining Region in China,a key energy base ...Clarifying the mechanisms through which coal mining affects groundwater storage(GWS)variations is crucial for water resource conservation and sustainable development.The Ordos Mining Region in China,a key energy base in China with significant strategic importance,has undergone intensive coal mining activities that have substantially disrupted regional groundwater circulation.This study integrated data from the Gravity Recovery and Climate Experiment Satellite(GRACE)and Famine Early Warning Systems Network(FEWS NET)Land Data Assimilation System(FLDAS)models,combined with weighted downscaling methodology and water balance principles,to reconstruct high-resolution(0.01°)terrestrial water storage(TWS)and GWS changes in the Ordos Mining Region,China from April 2002 to December 2021.The accuracy of GWS variations were validated through pumping test measurements.Subsequently,Geodetector analysis was implemented to quantify the contributions of natural and anthropogenic factors to groundwater storage dynamics.Key findings include:1)TWS in the study area showed a fluctuating but overall decreasing trend,with a total reduction of 8901.11 mm during study period.The most significant annual decrease occurred in 2021,reaching 1696.77 mm.2)GWS exhibited an accelerated decline,with an average annual change rate of 44.35 mm/yr,totaling a decrease of 887.05 mm.The lowest annual groundwater storage level was recorded in 2020,reaching 185.69 mm.3)Precipitation(PRE)contributed the most to GWS variation(q=0.52),followed by coal mining water consumption(MWS)(q=0.41).The interaction between PRE and MWS exhibited a nonlinear enhancement effect on GWS changes(0.54).The synergistic effect of natural hydrological factors has a great influence on the change of GWS,but coal mining water consumption will continue to reduce GWS.These findings provide critical references for the management and regulation of groundwater resource in mining regions.展开更多
Purpose–This study aims to design and validate an emergency response method for high-speed railway earthquake early warning(EEW)systems based on the Propagation of Local Undamped Motion(PLUM)principle in order to enh...Purpose–This study aims to design and validate an emergency response method for high-speed railway earthquake early warning(EEW)systems based on the Propagation of Local Undamped Motion(PLUM)principle in order to enhance the timeliness and accuracy of warnings under seismic threats.Design/methodology/approach–A hierarchical architecture of the railway EEW system was adopted,in which self-built stations along the railway serve as the backbone and the national seismic network provides supplementary data.Warning zones were designed along the railway using overlapping trapezoidal layouts to cover seismic stations and reduce inter-regional time delays.Offline replay experiments were conducted using 82 historical earthquake events and records from 61 seismic stations to evaluate the timeliness and accuracy of warning information.Findings–The results indicate that the PLUM-based early warning method can issue emergency response information before destructive seismic waves arrive.Multiple earthquake experiments demonstrated high reliability and stability,with effective detection across different magnitudes and epicentral distances.Furthermore,the trapezoidal overlapping zone design improved regional consistency and significantly reduced missed alerts.Originality/value–This work represents the first systematic application of the PLUM method to high-speed railway EEW in China.By integrating railway operational requirements,the proposed method provides a practical and robust emergency response strategy,offering new insights into seismic risk mitigation for China’s high-speed railways.展开更多
Emphysematous pyelonephritis(EPN)is a severe,a lethal necrotizing upper urinary tract infection,characterized by gas production within the renal pa-renchyma,collecting system,or perinephric tissue.EPN is emerging as a...Emphysematous pyelonephritis(EPN)is a severe,a lethal necrotizing upper urinary tract infection,characterized by gas production within the renal pa-renchyma,collecting system,or perinephric tissue.EPN is emerging as a sig-nificant concern,necessitating early diagnosis,severity assessment,and timely intervention to improve outcomes.This study proposes a modified National Early Warning Score 2(mNEWS 2)to enhance risk stratification and predictive accuracy in EPN management.The mNEWS 2 refines the original NEWS 2 system,which aggregates 6 physiological indicators(body temperature,systolic blood pressure,pulse rate,oxygen saturation,breathing rate,and degree of consciousness),by incorporating weighted risk stratification indices and specific cutoff values derived from clinical observations,statistical modeling,and predictive per-formance analysis.A pilot study identified optimal thresholds,with a score of 15 maximizing predictive performance for mortality risk and intervention needs,validated through receiver operating characteristic curve analysis.So,the mNEWS 2 score represents a significant advancement in EPN management,offering improved risk stratification and treatment outcomes.展开更多
Objective:To identify predictive factors for brucellosis by analyzing cases with and without focal involvement.Methods:This single-center retrospective study included adults(≥18 years)diagnosed with brucellosis at Ağ...Objective:To identify predictive factors for brucellosis by analyzing cases with and without focal involvement.Methods:This single-center retrospective study included adults(≥18 years)diagnosed with brucellosis at AğrıTraining and Research Hospital between January 1,2022 and December 31,2024.Patients were evaluated for organ involvement based on localized symptoms and classified accordingly.Logistic regression analysis was performed to identify demographic,clinical,and laboratory predictors of organ involvement.Results:A total of 210 cases were analyzed including 115 females(54.8%)and 95 males(45.2%).Among patients with focal involvement,the proportion of males was higher(54.4%),and comorbidities were also more common(34.4%).Days of complaints before hospital admission was significantly longer in patients with focal involvement(median 31 days)compared to those without focal involvement(median 20 days)(P=0.004).Lower back pain and testicular pain were more common in focal cases,with elevated levels of leukocytes,neutrophils,monocytes,C-reactive protein,and erythrocyte sedimentation rate(ESR).Osteoarticular involvement was found in 61/90 cases(67.7%).Logistic regression identified male sex(OR 2.56;95%CI 1.29-5.04),subacute(OR 3.74;95%CI 1.36-10.32)or chronic presentation(OR 29.01;95%CI 2.96-284.20),and elevated ESR(OR 1.03;95%CI 1.01-1.05)as independent risk factors for focal involvement.The model explained 33.9%of the variance,with 74.3%accuracy.Conclusions:Male sex,subacute or chronic brucellosis,and elevated ESR are key risk factors for focal brucellosis.展开更多
基金supported by the Scientific Research Projects of the Education Department of Zhejiang Province(Grant No.Y202454744)the Ningbo Public Welfare Science and Technology Project(Grant No.2024S077)+1 种基金International Sci-tech Cooperation Projects under the“Innovation Yongjiang 2035”Key R&D Programme(No.2024H019)the Ningbo Key R&D Program(Grant No.2024Z287).
文摘The existing 2D settlement monitoring systems for utility tunnels are heavily reliant on manual interpretation of deformation data and empirical predictionmodels.Consequently,early anomalies(e.g.,minor cracks)are often misjudged,and warnings lag by about 24 h without automated spatial localization.This study establishes a technical framework for requirements analysis,architectural design,and data-integration protocols.Revit parametric modelling is used to build a 3D tunnel model with structural elements,pipelines and 18 monitoring points(for displacement and joint width).Custom Revit API code integrated real-time sensor data into the BIM platform via an automated pipeline.The system achieved a spatial accuracy of±1 mm in locating deformation hotspots.Notifications are triggered within 10 s of anomaly detection,and the system renders 3D risk propagation paths in real-time.Realtime 3D visualization of risk propagation paths is also facilitated.The efficacy of the solution was validated in a Ningbo utility tunnel project,where it was demonstrated that it eliminates human-dependent judgment errors and reduces warning latency by 99.9%compared to conventional methods.The BIM-IoT integrated approach,which enables millimetre-level precision in risk identification and near-instantaneous response,establishes a new paradigm for intelligent infrastructure safety management.
基金support from the Sichuan Science and Technology Program(Grant No.2023NSFSC0812).
文摘The effective early warning of surrounding rock mass deformation is crucial in geotechnical engineering for ensuring the safety and stability of underground constructions.This study introduces a novel risk early warning model based on multi-parameter fuzzy comprehensive evaluation,which quantitatively assesses the risk state of the surrounding rock mass.The microseismic(MS)monitoring system is set up for the underground powerhouse.The spatial and temporal distribution of MS events and the frequency characteristics of MS signals are analyzed during the top arch excavation.The early warning indices for characterizing MS spatial aggregation and frequency-energy dispersion are proposed based on the octree theory to assess the deformation of the surrounding rock mass.The risk warning model for the surrounding rock mass in underground engineering is developed through the integration of the formulated index and the frequency characteristics of MS signals.The results indicate that the multiparameter fuzzy comprehensive assessment model can achieve three-dimensional visualization of risk warnings for the surrounding rock mass.The quantitative results regarding warning time and potential deformation areas are highly consistent with the characteristics of MS precursors.These research results can provide an important reference for early warning of surrounding rock mass risk in similar underground projects.
基金support from the National Natural Science Foundation of China(Grant Nos.52104207 and 52374214)the Shandong Provincial Youth Innovation Team Development Program for Higher Education Institutions(Grant No.2023KJ305).
文摘In the field of rock engineering,the influence of water is a dynamic process that exhibits varying effects over time and across different locations.To further understand how water influences the mechanical properties and acoustic emission(AE)behavior of rocks,this study conducted uniaxial compression experiments on sandstones with varying degrees of wetting under both natural conditions and water-chemical environments.In addition,the study combined AE equipment with digital image correlation(DIC)to monitor the entire failure process.Using the sliding window algorithm,the variation in the variance of AE characteristic parameters during the process of sandstone loading to failure is analyzed from the perspective of critical slowing down.This analysis enables the effective identification of the early warning signal before failure.The experimental findings suggest that an increase in wetting height results in a gradual decrease in peak stress,accompanied by a concomitant increase in the percentage of shear cracks.The characteristic parameters,including energy,amplitude,and ringing count,all exhibit critical slowing phenomena.The waveform of AE characteristic parameters of the same sample is similar,and the mutation time of the precursor signal is roughly the same.All signals appear in the irreversible plastic deformation stage of microcrack initiation.The integration of critical slowing down theory and the b-value early warning method facilitates a more comprehensive evaluation of the stability of rock mass,thereby significantly enhancing the efficiency and safety of disaster prevention measures.
基金supported by the National Key Research and Development Project of the National Natural Science Foundation of China(Grant No.2022YFC3004605)the National Natural Science Foundation of China Youth Science Fund(Grant No.52104087).
文摘To advance the theoretical understanding,technological development,and field application of electric charge induction for monitoring rock deformation and failure,this study investigates the induced electric charge generated during the deformation and failure of igneous rocks.The charge originates mainly from a combination of electrical polarization and triboelectric effects.Through laboratory experiments,we analyzed the time-frequency evolution of induced electric charge signals and identified relevant monitoring parameters.An online downhole electric charge induction monitoring system was developed and validated in the field.Experimental results show that the dominant frequency range of induced electric charge signals generated during igneous rock deformation and failure lies between 0 and 23 Hz,and a low-pass finite impulse response(FIR)filter effectively suppresses noise.Optimal sensor distances for monitoring cubic and cylindrical specimens were determined to be 17 mm and 13 mm,respectively.We proposed early warning indicators,including the maximum absolute value of the induced electric charge,the arithmetic mean value,the distribution dispersion coefficient,and the cumulative sum value.In field application,time-domain curves and spatial distribution charts of these warning indicators correspond well with changes in abutment stress ahead of the mining face,offering indirect insights into local stress evolution.This research provides technical and equipment support for the application of electric charge induction technology to monitoring and early warning of coal bursts.
文摘【选注者言:这是一则“出口转内销”的文章。我在近日的《北京日报》上读到了这篇带“警告性”的短文,不料在Yahoo News里也刊登了英国路透社从北京发出的这则消息,我在网上“冲浪”时,又读该文,觉得别有兴味。我的一个远亲购置了新屋,以花岗岩石铺地,豪华气派,雍容华贵。在读了最近新华社发的文章后,我的亲戚举家心情沮丧,顿感肺部不适,不知是心理作用,还是真的受到了radioactive gas(放射性气体)的刺激。很快就请人重铺地面,心情和肺部均不再有任何不适。我将本文发给你们,目的是为了让更多的购房者少走弯路,“趋吉避凶”。本文末句把国人的装修归结到spending spree(消费狂热)the government wants to encourage to boost(推进)the economy。给人一种过于牵强的感觉。】
基金research was funded by Science and Technology Project of State Grid Corporation of China under grant number 5200-202319382A-2-3-XG.
文摘Iced transmission line galloping poses a significant threat to the safety and reliability of power systems,leading directly to line tripping,disconnections,and power outages.Existing early warning methods of iced transmission line galloping suffer from issues such as reliance on a single data source,neglect of irregular time series,and lack of attention-based closed-loop feedback,resulting in high rates of missed and false alarms.To address these challenges,we propose an Internet of Things(IoT)empowered early warning method of transmission line galloping that integrates time series data from optical fiber sensing and weather forecast.Initially,the method applies a primary adaptive weighted fusion to the IoT empowered optical fiber real-time sensing data and weather forecast data,followed by a secondary fusion based on a Back Propagation(BP)neural network,and uses the K-medoids algorithm for clustering the fused data.Furthermore,an adaptive irregular time series perception adjustment module is introduced into the traditional Gated Recurrent Unit(GRU)network,and closed-loop feedback based on attentionmechanism is employed to update network parameters through gradient feedback of the loss function,enabling closed-loop training and time series data prediction of the GRU network model.Subsequently,considering various types of prediction data and the duration of icing,an iced transmission line galloping risk coefficient is established,and warnings are categorized based on this coefficient.Finally,using an IoT-driven realistic dataset of iced transmission line galloping,the effectiveness of the proposed method is validated through multi-dimensional simulation scenarios.
文摘In order to solve the problems of high coupling and poor scalability of the traditional monomer early warning release system architecture,multi-level deployment in a complex network environment will lead to high investment in software and hardware and cannot achieve intensive multi-level deployment.This paper realizes the goal of system scalability by introducing micro service architecture and technology stack and realizes the goal of resource intensification by introducing the idea of a data forwarding agent.The designed architecture scheme has been practically applied in the“Jiangxi emergency early warning information release system software platform(phase I)project”(hereinafter referred to as“provincial emergency”),which meets the needs of flexible deployment of multi-level applications across meteorological wide area network(WAN),business private network of other commissions,offices,and bureaus,government extranet,Internet and other complex networks,and fully verifies the scientificity and rationality of the scheme.It has achieved the goal of intensive and scalable construction of provincial emergencies under the complex network environment,greatly improved the early warning capacity and communication capacity of emergencies and comprehensive disasters,provided a reliable guarantee for disaster prevention and reduction,and provided a reference for the construction of current and future early warning release system and capacity improvement project.
文摘BACKGROUND Emphysematous pyelonephritis(EPN)is a life-threatening necrotizing renal parenchyma infection characterized by gas formation due to severe bacterial infection,predominantly affecting diabetic and immunocompromised patients.It carries high morbidity and mortality,requiring early diagnosis and timely intervention.Various prognostic scoring systems help in triaging critically ill patients.The National Early Warning Score 2(NEWS 2)scoring system is a widely used physiological assessment tool that evaluates clinical deterioration based on vital parameters,but its standard form lacks specificity for risk stratification in EPN,necessitating modifications to improve treatment decisionmaking and prognostic accuracy in this critical condition.AIM To highlight the need to modify the NEWS 2 score to enable more intense monitoring and better treatment outcomes.METHODS This prospective study was done on all EPN patients admitted to our hospital over the past 12 years.A weighted average risk-stratification index was calculated for each of the three groups,mortality risk was calculated for each of the NEWS 2 scores,and the need for intervention for each of the three groups was calculated.The NEWS 2 score was subsequently modified with 0-6,7-14 and 15-20 scores included in groups 1,2 and 3,respectively.RESULTS A total of 171 patients with EPN were included in the study,with a predominant association with diabetes(90.6%)and a female-to-male ratio of 1.5:1.The combined prognostic scoring of the three groups was 10.7,13.0,and 21.9,respectively(P<0.01).All patients managed conservatively belonged to group 1(P<0.01).Eight patients underwent early nephrectomy,with six from group 3(P<0.01).Overall mortality was 8(4.7%),with seven from group 3(87.5%).The cutoff NEWS 2 score for mortality was identified to be 15,with a sensitivity of 87.5%,specificity of 96.9%,and an overall accuracy rate of 96.5%.The area under the curve to predict mortality based on the NEWS 2 score was 0.98,with a confidence interval of(0.97,1.0)and P<0.001.CONCLUSION Modified NEWS 2(mNEWS 2)score dramatically aids in the appropriate assessment of treatment-related outcomes.MNEWS 2 scores should become the practice standard to reduce the morbidity and mortality associated with this dreaded illness.
基金the financial support of the Key Technologies Research and Development Program(Grant No.2022YFC3003302)the National Natural Science Foundation of China(Grant Nos.51934007 and 52104230).
文摘Deep coal-energy mining frequently results in microseismic(MS)events,which may be a precursor to the risk of rockbursts and pose risks to human safety and infrastructure.Therefore,quantitatively predicting the time,energy,and location(TEL)of future MS events is crucial for understanding and preventing potential catastrophic events.In this study,we introduced the application of spatiotemporal graph convolutional networks(STGCN)to predict the TEL of MS events induced by deep coal-energy mining.Notably,this was the first application of graph convolution networks(GCNs)in the spatiotemporal prediction of MS events.The adjacency matrices of the sensor networks were determined based on the distance between MS sensors,the sensor network graphs we constructed,and GCN was employed to extract the spatiotemporal details of the graphs.The model is simple and versatile.By testing the model with on-site MS monitoring data,our results demonstrated promising efficacy in predicting the TEL of MS events,with the cosine similarity(C)above 0.90 and the mean relative error(MRE)below 0.08.This is critical to improving the safety and operational efficiency of deep coal-energy mining.
基金supported by the National Natural Science Foundation of China(52476200,52106244)the Guangdong Basic and Applied Basic Research Foundation(2024A1515030124)+1 种基金the Science and Technology Project of China Southern Power Grid under Grant GDKJXM20230246(030100KC23020017)the Fundamental Research Funds for the Central Universities。
文摘Due to batteries inconsistencies and potential faults in battery management systems,slight overcharging remains a common yet insufficiently understood safety risk,lacking effective warning methods.To illuminate the degradation behavior and failure mechanism of various overcharged states(100%SOC,105%SOC,110%SOC,and 115%SOC),multiple advanced in-situ characterization techniques(accelerating rate calorimeter,electrochemical impedance spectroscopy,ultrasonic scanning,and expansion instrument)were utilized.Additionally,re-overcharge-induced thermal runaway(TR)tests were conducted,with a specific emphasis on the evolution of the expansion force signal.Results indicated significant degradation at 110%SOC including conductivity loss,loss of lithium inventory,and loss of active material accompanied by internal gas generation.These failure behaviors slow down the expansion force rate during reovercharging,reducing the efficacy of active warnings that depend on rate thresholds of expansion force.Specifically,the warning time for 115%SOC battery is only 144 s,which is 740 s shorter than that for fresh battery,and the time to TR is advanced by 9 min.Moreover,the initial self-heating temperature(T1)is reduced by 62.4℃compared to that of fresh battery,reaching only 70.8℃.To address the low safety of overcharged batteries,a passive overcharge warning method utilizing relaxation expansion force was proposed,based on the continued gas generation after stopping charging,leading to a sustained increase in force.Compared to active methods that rely on thresholds of expansion force rate,the passive method can issue warnings 115 s earlier.By combining the passive and active warning methods,guaranteed effective overcharge warning can be issued 863-884 s before TR.This study introduces a novel perspective for enhancing the safety of batteries.
基金support by the National Natural Science Foundation of China(52201077)the Natural Science Foundation of Shandong Province(ZR2022QE191)+1 种基金Elite Scheme of Shandong University of Science and Technology(0104060541123)Talent introduction and Research Start-up Fund of Shandong University of Science and Technology(0104060510124).
文摘Coating microdefects and localized corrosion in coating/metal system are inevitable,accelerating the degradation of metal infrastructure.Early evaluating coating microdefects and detecting corrosion sites are urgent yet remain challenge to achieve.Herein,we propose a robust,universal and efficient fluorescence-based strategy for hierarchical warning of coating damage and metal corrosion by introducing the concepts of damage-induced fluorescence enhancement effect(DIE)and ionic-recognition induced quenching effect(RIQ).The coatings with dualresponsiveness for coating defect and steel corrosion are constructed by incorporating synthesized nanoprobes composed of metal organic frameworks(Ni–Zn-MOFs)loaded with Rhodamine B(RhB@MOFs).The initial damage to the coating causes an immediate intensification of fluorescence,while the specific ionic-recognition characteristic of RhB with Fe3t results in an evident fluorescence quenching,enabling the detection of coating damage and corrosion.Importantly,this nanoprobes are insensitive to the coating matrix and exhibit stable corrosion warning capability across various coating systems.Meanwhile,electrochemical investigations indicate that the impedance values of RM/EP maintain above 10^(8)Ωcm^(2)even after 60 days of immersion.Therefore,the incorporation of fluorescent nanoprobes greatly inhibits the intrusion of electrolytes into polymer and improves the corrosion protection performance of the coating.This powerful strategy towards dual-level damage warning provides insights for the development of long-term smart protective materials.
基金funding support from Guiding Project of Scientific Research Plan of Education Department of Hubei Province and Wuhan Textile University School Fund(B)(k24016).
文摘Enhancing the firefighting protective clothing with exceptional thermal barrier and temperature sensing functions to ensure high fire safety for firefighters has long been anticipated,but it remains a major challenge.Herein,inspired by the human muscle,an anisotropic fire safety aerogel(ACMCA)with precise self-actuated temperature monitoring performance is developed by combining aramid nanofibers with eicosane/MXene to form an anisotropically oriented conductive network.By combining the two synergies of the negative temperaturedependent thermal conductive eicosane,which induces a high-temperature differential,and directionally ordered MXene that establishes a conductive network along the directional freezing direction.The resultant ACMCA exhibited remarkable thermoelectric properties,with S values reaching 46.78μV K^(−1)andκvalues as low as 0.048 W m^(−1)K^(−1)at room temperature.Moreover,the prepared anisotropic aerogel ACMCA exhibited electrical responsiveness to temperature variations,facilitating its application in intelligent temperature monitoring systems.The designed anisotropic aerogel ACMCA could be incorporated into the firefighting clothing as a thermal barrier layer,demonstrating a wide temperature sensing range(50-400℃)and a rapid response time for early high-temperature alerts(~1.43 s).This work provides novel insights into the design and application of temperature-sensitive anisotropic aramid nanofibers aerogel in firefighting clothing.
基金supported by the Basic Ability Improvement Project of Young and Middle-Aged Teachers in Colleges and Universities of Guangxi(2022KY1922,2021KY1938).
文摘The traditional academic warning methods for students in higher vocational colleges are relatively backward,single,and have many influencing factors,which have a limited effect on improving their learning ability.A data set was established by collecting academic warning data of students in a certain university.The importance of the school,major,grade,and warning level for the students was analyzed using the Pearson correlation coefficient,random forest variable importance,and permutation importance.It was found that the characteristic of the major has a great impact on the academic warning level.Countermeasures such as dynamic adjustment of majors,reform of cognitive adaptation of courses,full-cycle academic support,and data-driven precise intervention were proposed to provide theoretical support and practical paths for universities to improve the efficiency of academic warning and enhance students’learning ability.
基金Youth Foundation of National Natural Science Foundation of China (No. 52204020)Distinguished Young Foundation of National Natural Science Foundation of China (No. 52125401).
文摘As oil and gas exploration continues to progress into deeper and unconventional reservoirs,the likelihood of kick risk increases,making kick warning a critical factor in ensuring drilling safety and efficiency.Due to the scarcity of kick samples,traditional supervised models perform poorly,and significant fluctuations in field data lead to high false alarm rates.This study proposes an unsupervised graph autoencoder(GAE)-based kick warning method,which effectively reduces false alarms by eliminating the influence of field engineer operations and incorporating real-time model updates.The method utilizes the GAE model to process time-series data during drilling,accurately identifying kick risk while overcoming challenges related to small sample sizes and missing features.To further reduce false alarms,the weighted dynamic time warping(WDTW)algorithm is introduced to identify fluctuations in logging data caused by field engineer operations during drilling,with real-time updates applied to prevent normal conditions from being misclassified as kick risk.Experimental results show that the GAE-based kick warning method achieves an accuracy of 92.7%and significantly reduces the false alarm rate.The GAE model continues to operate effectively even under conditions of missing features and issues kick warnings 4 min earlier than field engineers,demonstrating its high sensitivity and robustness.After integrating the WDTW algorithm and real-time updates,the false alarm rate is reduced from 17.3%to 5.6%,further improving the accuracy of kick warnings.The proposed method provides an efficient and reliable approach for kick warning in drilling operations,offering strong practical value and technical support for the intelligent management of future drilling operations.
基金the National Research Institute of Astronomy and Geophysics (NRIAG) for supporting this work
文摘The level of ground shaking,as determined by the peak ground acceleration(PGA),can be used to analyze seismic hazard at a certain location and is crucial for constructing earthquake-resistant structures.Predicting the PGA immediately after an earthquake occurs allows for the issuing of a warning by an earthquake early warning system.In this study,we propose a deep learning model,ConvMixer,to predict the PGA recorded by weak-motion velocity seismometers in Japan.We use 5-s threecomponent seismograms,from 2 s before until 3 s after the P-wave arrival time of the earthquake.Our dataset comprised more than 50,000 single-station waveforms recorded by 10 seismic stations in the K-NET,Kiki-NET,and Hi-Net networks between 2004 and 2023.The proposed ConvMixer is a patch-based model that extracts global features from input seismic data and predicts the PGA of an earthquake by combining depth and pointwise convolutions.The proposed ConvMixer network had a mean absolute error of 2.143 when applied to the test set and outperformed benchmark deep learning models.In addition,the proposed ConvMixer demonstrated the ability to predict the PGA at the corresponding station site based on 1-second waveforms obtained immediately after the arrival time of the P-wave.
基金Under the National Key R&D Program Key Project(No.2021YFC3201201)National Natural Science Foundation of China(No.52360032)+2 种基金Basic Scientific Research Business Fee Project of Colleges And Universities Directly Under the Inner Mongolia Autonomous Region(No.JBYYWF2022001)Development Plan of Innovation Team of Colleges And Universities in Inner Mongolia Autonomous Region(No.NMGIRT2313)the Innovation Team of‘Grassland Talents’。
文摘Clarifying the mechanisms through which coal mining affects groundwater storage(GWS)variations is crucial for water resource conservation and sustainable development.The Ordos Mining Region in China,a key energy base in China with significant strategic importance,has undergone intensive coal mining activities that have substantially disrupted regional groundwater circulation.This study integrated data from the Gravity Recovery and Climate Experiment Satellite(GRACE)and Famine Early Warning Systems Network(FEWS NET)Land Data Assimilation System(FLDAS)models,combined with weighted downscaling methodology and water balance principles,to reconstruct high-resolution(0.01°)terrestrial water storage(TWS)and GWS changes in the Ordos Mining Region,China from April 2002 to December 2021.The accuracy of GWS variations were validated through pumping test measurements.Subsequently,Geodetector analysis was implemented to quantify the contributions of natural and anthropogenic factors to groundwater storage dynamics.Key findings include:1)TWS in the study area showed a fluctuating but overall decreasing trend,with a total reduction of 8901.11 mm during study period.The most significant annual decrease occurred in 2021,reaching 1696.77 mm.2)GWS exhibited an accelerated decline,with an average annual change rate of 44.35 mm/yr,totaling a decrease of 887.05 mm.The lowest annual groundwater storage level was recorded in 2020,reaching 185.69 mm.3)Precipitation(PRE)contributed the most to GWS variation(q=0.52),followed by coal mining water consumption(MWS)(q=0.41).The interaction between PRE and MWS exhibited a nonlinear enhancement effect on GWS changes(0.54).The synergistic effect of natural hydrological factors has a great influence on the change of GWS,but coal mining water consumption will continue to reduce GWS.These findings provide critical references for the management and regulation of groundwater resource in mining regions.
文摘Purpose–This study aims to design and validate an emergency response method for high-speed railway earthquake early warning(EEW)systems based on the Propagation of Local Undamped Motion(PLUM)principle in order to enhance the timeliness and accuracy of warnings under seismic threats.Design/methodology/approach–A hierarchical architecture of the railway EEW system was adopted,in which self-built stations along the railway serve as the backbone and the national seismic network provides supplementary data.Warning zones were designed along the railway using overlapping trapezoidal layouts to cover seismic stations and reduce inter-regional time delays.Offline replay experiments were conducted using 82 historical earthquake events and records from 61 seismic stations to evaluate the timeliness and accuracy of warning information.Findings–The results indicate that the PLUM-based early warning method can issue emergency response information before destructive seismic waves arrive.Multiple earthquake experiments demonstrated high reliability and stability,with effective detection across different magnitudes and epicentral distances.Furthermore,the trapezoidal overlapping zone design improved regional consistency and significantly reduced missed alerts.Originality/value–This work represents the first systematic application of the PLUM method to high-speed railway EEW in China.By integrating railway operational requirements,the proposed method provides a practical and robust emergency response strategy,offering new insights into seismic risk mitigation for China’s high-speed railways.
文摘Emphysematous pyelonephritis(EPN)is a severe,a lethal necrotizing upper urinary tract infection,characterized by gas production within the renal pa-renchyma,collecting system,or perinephric tissue.EPN is emerging as a sig-nificant concern,necessitating early diagnosis,severity assessment,and timely intervention to improve outcomes.This study proposes a modified National Early Warning Score 2(mNEWS 2)to enhance risk stratification and predictive accuracy in EPN management.The mNEWS 2 refines the original NEWS 2 system,which aggregates 6 physiological indicators(body temperature,systolic blood pressure,pulse rate,oxygen saturation,breathing rate,and degree of consciousness),by incorporating weighted risk stratification indices and specific cutoff values derived from clinical observations,statistical modeling,and predictive per-formance analysis.A pilot study identified optimal thresholds,with a score of 15 maximizing predictive performance for mortality risk and intervention needs,validated through receiver operating characteristic curve analysis.So,the mNEWS 2 score represents a significant advancement in EPN management,offering improved risk stratification and treatment outcomes.
文摘Objective:To identify predictive factors for brucellosis by analyzing cases with and without focal involvement.Methods:This single-center retrospective study included adults(≥18 years)diagnosed with brucellosis at AğrıTraining and Research Hospital between January 1,2022 and December 31,2024.Patients were evaluated for organ involvement based on localized symptoms and classified accordingly.Logistic regression analysis was performed to identify demographic,clinical,and laboratory predictors of organ involvement.Results:A total of 210 cases were analyzed including 115 females(54.8%)and 95 males(45.2%).Among patients with focal involvement,the proportion of males was higher(54.4%),and comorbidities were also more common(34.4%).Days of complaints before hospital admission was significantly longer in patients with focal involvement(median 31 days)compared to those without focal involvement(median 20 days)(P=0.004).Lower back pain and testicular pain were more common in focal cases,with elevated levels of leukocytes,neutrophils,monocytes,C-reactive protein,and erythrocyte sedimentation rate(ESR).Osteoarticular involvement was found in 61/90 cases(67.7%).Logistic regression identified male sex(OR 2.56;95%CI 1.29-5.04),subacute(OR 3.74;95%CI 1.36-10.32)or chronic presentation(OR 29.01;95%CI 2.96-284.20),and elevated ESR(OR 1.03;95%CI 1.01-1.05)as independent risk factors for focal involvement.The model explained 33.9%of the variance,with 74.3%accuracy.Conclusions:Male sex,subacute or chronic brucellosis,and elevated ESR are key risk factors for focal brucellosis.
