Cotton fiber development is a highly programmed process,involving a large number of genes.Through cDNA array and RT-PCR,we isolated a Gossypium hirsutum RD22-1 like gene(GhRDL1),
When World War I ended in 1918 the aviators wanting to fly higher and further and they started a raced in which everyone wanted to be first. The Spanish pilots were initially excluded by the Moroccan War, which demand...When World War I ended in 1918 the aviators wanting to fly higher and further and they started a raced in which everyone wanted to be first. The Spanish pilots were initially excluded by the Moroccan War, which demanded all available air forces be used to put an end to the conflict. Motivated by the successes of The Alhucemas amphibious landing, one of best Spanish aviators, Major Ramon Franco presented to the Government in 1925 a project to undertake a flight to Argentina across the South Atlantic Ocean in a DornierJ Wal seaplane. In the memorandum, Franco said： The Spain-Argentina flight would be a worthwhile trial and verification of air navigation. It would also serve to let the entire world know of the merits of our Aviation and allow us to occupy the aeronautical place that belongs to us in aeronautics. It would also help us strengthen our ties with our brothers at the other side of the ocean. The DornierJ Walwas named ＂Plus Ultra＂ referring to the Discovery of America. The route should be Palos de la Frontera-Las Palmas de Gran Canaria-Cape Verde islands-Fernando Noronha island-Pernambuco-Rio de Janeiro-Montevideo and Buenos Aires. Franco reasoned that the best time of year to make the flight was from December to April. The raid started in the city Palos de la Frontera on 22 January 1926 and ended in Buenos Aires on February 9, after flying 10,825 kilometers in 59 hours and 48 minutes.展开更多
Connexins family in humans consists of 21 highly conserved proteins that are responsible for contact formation between cells. On the cell surface, connexins form hemichannels, or connexons. Two hemichannels brought to...Connexins family in humans consists of 21 highly conserved proteins that are responsible for contact formation between cells. On the cell surface, connexins form hemichannels, or connexons. Two hemichannels brought together form a gap junction, a form of intercellular contact that allows for direct transfer of material and signals between the adjacent cells. Gap junctions serve for transporting ions and other soluble, low molecular weight molecules therefore synchronizing the microenvironment of the contacting cells and maintaining cell and tissue homeostasis. Impairment of gap junctions is associated with different pathological conditions. Importantly, it has been described in atherosclerosis, which causes local cellular dysfunction in the arterial wall tissues followed by the development of atherosclerotic plaque. There are 3 main connexins expressed in human cardiovascular system: Cx37, Cx40, and Cx43. Alterations in the arterial wall cells observed in atherosclerosis include changes in the expression pattern of the main connexins and impairment of intercellular contacts and communication. According to the currently available data, Cx37 and Cx40 have anti-atherogenic and vasculoprotective properties, while Cx43 appears to be more pro-atherogenic. However, the effects of connexins are cell type-dependent and in many cases, remain to be studied in detail. In this review, we summarize the available knowledge on connexins of the arterial wall cells involved in atherosclerosis development.展开更多
文摘Cotton fiber development is a highly programmed process,involving a large number of genes.Through cDNA array and RT-PCR,we isolated a Gossypium hirsutum RD22-1 like gene(GhRDL1),
文摘When World War I ended in 1918 the aviators wanting to fly higher and further and they started a raced in which everyone wanted to be first. The Spanish pilots were initially excluded by the Moroccan War, which demanded all available air forces be used to put an end to the conflict. Motivated by the successes of The Alhucemas amphibious landing, one of best Spanish aviators, Major Ramon Franco presented to the Government in 1925 a project to undertake a flight to Argentina across the South Atlantic Ocean in a DornierJ Wal seaplane. In the memorandum, Franco said： The Spain-Argentina flight would be a worthwhile trial and verification of air navigation. It would also serve to let the entire world know of the merits of our Aviation and allow us to occupy the aeronautical place that belongs to us in aeronautics. It would also help us strengthen our ties with our brothers at the other side of the ocean. The DornierJ Walwas named ＂Plus Ultra＂ referring to the Discovery of America. The route should be Palos de la Frontera-Las Palmas de Gran Canaria-Cape Verde islands-Fernando Noronha island-Pernambuco-Rio de Janeiro-Montevideo and Buenos Aires. Franco reasoned that the best time of year to make the flight was from December to April. The raid started in the city Palos de la Frontera on 22 January 1926 and ended in Buenos Aires on February 9, after flying 10,825 kilometers in 59 hours and 48 minutes.
基金the Russian Science Foundation (Grant # 18-15-00254).
文摘Connexins family in humans consists of 21 highly conserved proteins that are responsible for contact formation between cells. On the cell surface, connexins form hemichannels, or connexons. Two hemichannels brought together form a gap junction, a form of intercellular contact that allows for direct transfer of material and signals between the adjacent cells. Gap junctions serve for transporting ions and other soluble, low molecular weight molecules therefore synchronizing the microenvironment of the contacting cells and maintaining cell and tissue homeostasis. Impairment of gap junctions is associated with different pathological conditions. Importantly, it has been described in atherosclerosis, which causes local cellular dysfunction in the arterial wall tissues followed by the development of atherosclerotic plaque. There are 3 main connexins expressed in human cardiovascular system: Cx37, Cx40, and Cx43. Alterations in the arterial wall cells observed in atherosclerosis include changes in the expression pattern of the main connexins and impairment of intercellular contacts and communication. According to the currently available data, Cx37 and Cx40 have anti-atherogenic and vasculoprotective properties, while Cx43 appears to be more pro-atherogenic. However, the effects of connexins are cell type-dependent and in many cases, remain to be studied in detail. In this review, we summarize the available knowledge on connexins of the arterial wall cells involved in atherosclerosis development.
