A simple visual method for DNA detection during the formation of gold nanoparticles(AuNPs) was developed based on different electrostatic properties of single strand DNA(ssDNA) and double strand DNA(dsDNA).Since the s...A simple visual method for DNA detection during the formation of gold nanoparticles(AuNPs) was developed based on different electrostatic properties of single strand DNA(ssDNA) and double strand DNA(dsDNA).Since the ssDNA is easy to bind to AuNPs due to its exposed bases which could prevent saltinduced aggregation of AuNPs.The dsDNA always present negative charge because its negatively charged phosphate backbone is exposed.In this case,the dsDNA could disturb the adsorption between dsDNA and AuNPs and result in non-aggregation of AuNPs.After hybridization,chloroauric acid and ascorbic acid were added to the mixture solution,and the solution changed to red immediately and turned to purple in10 min in the present of target DNA.TEM results confirmed that the change of color stemed from aggregation of AuNPs.In order to obtain accurate results by naked eye,the DNA detection assay should be conducted under pH 7.0.展开更多
Mitigating increasing cyberattack incidents may require strategies such as reinforcing organizations’ networks with Honeypots and effectively analyzing attack traffic for detection of zero-day attacks and vulnerabili...Mitigating increasing cyberattack incidents may require strategies such as reinforcing organizations’ networks with Honeypots and effectively analyzing attack traffic for detection of zero-day attacks and vulnerabilities. To effectively detect and mitigate cyberattacks, both computerized and visual analyses are typically required. However, most security analysts are not adequately trained in visualization principles and/or methods, which is required for effective visual perception of useful attack information hidden in attack data. Additionally, Honeypot has proven useful in cyberattack research, but no studies have comprehensively investigated visualization practices in the field. In this paper, we reviewed visualization practices and methods commonly used in the discovery and communication of attack patterns based on Honeypot network traffic data. Using the PRISMA methodology, we identified and screened 218 papers and evaluated only 37 papers having a high impact. Most Honeypot papers conducted summary statistics of Honeypot data based on static data metrics such as IP address, port, and packet size. They visually analyzed Honeypot attack data using simple graphical methods (such as line, bar, and pie charts) that tend to hide useful attack information. Furthermore, only a few papers conducted extended attack analysis, and commonly visualized attack data using scatter and linear plots. Papers rarely included simple yet sophisticated graphical methods, such as box plots and histograms, which allow for critical evaluation of analysis results. While a significant number of automated visualization tools have incorporated visualization standards by default, the construction of effective and expressive graphical methods for easy pattern discovery and explainable insights still requires applied knowledge and skill of visualization principles and tools, and occasionally, an interdisciplinary collaboration with peers. We, therefore, suggest the need, going forward, for non-classical graphical methods for visualizing attack patterns and communicating analysis results. We also recommend training investigators in visualization principles and standards for effective visual perception and presentation.展开更多
Norfloxacin is widely used owing to its strong bactericidal effect on Gram-negative bacteria.However,the residual norfloxacin in the environment can be biomagnified via food chain andmay damage the human liver and del...Norfloxacin is widely used owing to its strong bactericidal effect on Gram-negative bacteria.However,the residual norfloxacin in the environment can be biomagnified via food chain andmay damage the human liver and delay the bone development ofminors.Present work described a reliable and sensitive smartphone colorimetric sensing system based on cobaltdoped Fe_(3)O_(4) magnetic nanoparticles(Co-Fe_(3)O_(4) MNPs)for the visual detection of norfloxacin.Compared with Fe_(3)O_(4),Co-Fe_(3)O_(4) MNPs earned more remarkably peroxidase-like activity and TMB(colorless)was rapidly oxidized to oxTMB(blue)with the presence of H_(2)O_(2).Interestingly,the addition of low concentration of norfloxacin can accelerate the color reaction process of TMB,and blue deepening of the solution can be observed with the naked eye.However,after adding high concentration of norfloxacin,the activity of nanozymewas inhibited,resulting in the gradual fading of the solution.Based on this principle,a colorimetric sensor integrated with smartphone RGB mode was established.The visual sensor exhibited good linearity for norfloxacin monitoring in the range of 0.13-2.51μmol/L and 17.5-100μmol/L.The limit of visual detectionwas 0.08μmol/L.In the actualwater sample analysis,the spiked recoveries of norfloxacin were over the range of 95.7%-104.7%.These results demonstrated that the visual sensor was a convenient and fast method for the efficient and accurate detection of norfloxacin in water,which may have broad application prospect.展开更多
A new method for visualizing sound propagation in solids and liquids is described in this paper. The method can show the sound propagation process dynamically in two dimensions. Compared with Schlieren method and dyna...A new method for visualizing sound propagation in solids and liquids is described in this paper. The method can show the sound propagation process dynamically in two dimensions. Compared with Schlieren method and dynamic photo-elastic method, this method cannot only show the sound field distribution in liquid and solid at different time moments, but also can be applied to non-transparent solid. In addition, it does not strictly require small residual stress of the sample. The sample can, therefore, be easily made. Because the acoustic field is obtained by indirect measurements, the recording can be affected by the after-shock of the receiving sensor and is prone to the influence of the direct wave of the liquid. Putting an aluminum plate into a liquid, we recorded the compression wave, shear wave and surface wave in the aluminum and, in the liquid we also recorded the direct wave and three head waves, which are directly coupled with the compression wave, shear wave and surface wave respectively. The recording clearly depicts the coupling relationship of the sound waves through the interface between the aluminum and the liquid. Putting a plexiglass into a liquid, we also recorded the sound waves in the plexiglass and the coupling relationship between the sound waves in the two mediums.展开更多
To overcome the shortcomings of the traditional passive ranging technology based on image, such as poor ranging accuracy, low reliability and complex system, a new visual passive ranging method based on re-entrant coa...To overcome the shortcomings of the traditional passive ranging technology based on image, such as poor ranging accuracy, low reliability and complex system, a new visual passive ranging method based on re-entrant coaxial optical path is presented. The target image is obtained using double cameras with coaxial optical path. Since there is imaging optical path difference between the cameras, the images are different. In comparison of the image differences, the target range could be reversed. The principle of the ranging method and the ranging model are described. The relationship among parameters in the ranging process is analyzed quantitatively. Meanwhile,the system composition and technical realization scheme are also presented. Also, the principle of the method is verified by the equivalent experiment. The experimental results show that the design scheme is correct and feasible with good robustness. Generally, the ranging error is less than 10% with good convergence. The optical path is designed in a re-entrant mode to reduce the volume and weight of the system. Through the coaxial design,the visual passive range of the targets with any posture can be obtained in real time. The system can be widely used in electro-optical countermeasure and concealed photoelectric detection.展开更多
The study of marine data visualization is of great value. Marine data, due to its large scale, random variation and multiresolution in nature, are hard to be visualized and analyzed. Nowadays, constructing an ocean mo...The study of marine data visualization is of great value. Marine data, due to its large scale, random variation and multiresolution in nature, are hard to be visualized and analyzed. Nowadays, constructing an ocean model and visualizing model results have become some of the most important research topics of ‘Digital Ocean'. In this paper, a spherical ray casting method is developed to improve the traditional ray-casting algorithm and to make efficient use of GPUs. Aiming at the ocean current data, a 3D view-dependent line integral convolution method is used, in which the spatial frequency is adapted according to the distance from a camera. The study is based on a 3D virtual reality and visualization engine, namely the VV-Ocean. Some interactive operations are also provided to highlight the interesting structures and the characteristics of volumetric data. Finally, the marine data gathered in the East China Sea are displayed and analyzed. The results show that the method meets the requirements of real-time and interactive rendering.展开更多
目的探究抗菌包装领域研究的发展、研究热点及未来发展趋势,推动抗菌包装的发展。方法运用知识图谱与文献计量分析法,使用可视化分析软件CiteSpace对中国知网(CNKI)和Web of Science(WOS)数据库中2000—2024年抗菌包装领域的文献进行可...目的探究抗菌包装领域研究的发展、研究热点及未来发展趋势,推动抗菌包装的发展。方法运用知识图谱与文献计量分析法,使用可视化分析软件CiteSpace对中国知网(CNKI)和Web of Science(WOS)数据库中2000—2024年抗菌包装领域的文献进行可视化分析。结论相关文献的年发文量在整体上呈现出增长的趋势,尤其是英文文献的发文量增加显著;中文文献的研究成果在期刊分布上更为集中,外文文献则更为分散且学科覆盖更广;作者合作网络较为松散,其中国际的合作分化更为显著;通过对关键词分析显示,目前对抗菌包装的研究热点主要聚焦于抗菌材料、抗菌性能、食品保鲜应用,在未来的抗菌包装的研究中,抗菌包装的性能、新型抗菌成分与材料的开发和微观机制仍是主要研究热点,同时智能包装如环境响应型抗菌材料的研究、利用可生物降解材料与抗菌剂协同开发绿色抗菌材料将是未来的研究趋势。展开更多
目的探讨病种成本可视化分析系统的设计与构建。方法选择Power BI作为可视化分析工具。采集病种成本相关数据,导入Power BI并建立数据模型,编写度量值。采用Power BI Desktop设计可视化界面,对分析结果进行可视化展示,构建完整的病种成...目的探讨病种成本可视化分析系统的设计与构建。方法选择Power BI作为可视化分析工具。采集病种成本相关数据,导入Power BI并建立数据模型,编写度量值。采用Power BI Desktop设计可视化界面,对分析结果进行可视化展示,构建完整的病种成本可视化分析系统。结果可视化分析系统从总体概况、科室成本分析、DRG成本分析、DIP成本分析及病种成本分析五个角度进行分析展示,展示内容丰富,具有良好的洞察与分析效果。结论本研究应用Power BI快速实现了病种成本可视化分析系统的构建。病种成本可视化分析系统可为精细化管理和决策提供有效支持。展开更多
基金financially supported by the National Key Research and Development Program of China (No.2017YFA0205301)the National Natural Science Foundation of China (Nos.61527806, 81902153 and 61871180)+2 种基金the Natural Science Foundation of Hunan Province (No.2017JJ2069)the Hunan Key Research Project (No.2017SK2174)the Programs for Changjiang Scholars and Innovative Research Team in University (No.IRT_15R13)
文摘A simple visual method for DNA detection during the formation of gold nanoparticles(AuNPs) was developed based on different electrostatic properties of single strand DNA(ssDNA) and double strand DNA(dsDNA).Since the ssDNA is easy to bind to AuNPs due to its exposed bases which could prevent saltinduced aggregation of AuNPs.The dsDNA always present negative charge because its negatively charged phosphate backbone is exposed.In this case,the dsDNA could disturb the adsorption between dsDNA and AuNPs and result in non-aggregation of AuNPs.After hybridization,chloroauric acid and ascorbic acid were added to the mixture solution,and the solution changed to red immediately and turned to purple in10 min in the present of target DNA.TEM results confirmed that the change of color stemed from aggregation of AuNPs.In order to obtain accurate results by naked eye,the DNA detection assay should be conducted under pH 7.0.
文摘Mitigating increasing cyberattack incidents may require strategies such as reinforcing organizations’ networks with Honeypots and effectively analyzing attack traffic for detection of zero-day attacks and vulnerabilities. To effectively detect and mitigate cyberattacks, both computerized and visual analyses are typically required. However, most security analysts are not adequately trained in visualization principles and/or methods, which is required for effective visual perception of useful attack information hidden in attack data. Additionally, Honeypot has proven useful in cyberattack research, but no studies have comprehensively investigated visualization practices in the field. In this paper, we reviewed visualization practices and methods commonly used in the discovery and communication of attack patterns based on Honeypot network traffic data. Using the PRISMA methodology, we identified and screened 218 papers and evaluated only 37 papers having a high impact. Most Honeypot papers conducted summary statistics of Honeypot data based on static data metrics such as IP address, port, and packet size. They visually analyzed Honeypot attack data using simple graphical methods (such as line, bar, and pie charts) that tend to hide useful attack information. Furthermore, only a few papers conducted extended attack analysis, and commonly visualized attack data using scatter and linear plots. Papers rarely included simple yet sophisticated graphical methods, such as box plots and histograms, which allow for critical evaluation of analysis results. While a significant number of automated visualization tools have incorporated visualization standards by default, the construction of effective and expressive graphical methods for easy pattern discovery and explainable insights still requires applied knowledge and skill of visualization principles and tools, and occasionally, an interdisciplinary collaboration with peers. We, therefore, suggest the need, going forward, for non-classical graphical methods for visualizing attack patterns and communicating analysis results. We also recommend training investigators in visualization principles and standards for effective visual perception and presentation.
基金supported by the National Natural Science Foundation of China (No.21976211).
文摘Norfloxacin is widely used owing to its strong bactericidal effect on Gram-negative bacteria.However,the residual norfloxacin in the environment can be biomagnified via food chain andmay damage the human liver and delay the bone development ofminors.Present work described a reliable and sensitive smartphone colorimetric sensing system based on cobaltdoped Fe_(3)O_(4) magnetic nanoparticles(Co-Fe_(3)O_(4) MNPs)for the visual detection of norfloxacin.Compared with Fe_(3)O_(4),Co-Fe_(3)O_(4) MNPs earned more remarkably peroxidase-like activity and TMB(colorless)was rapidly oxidized to oxTMB(blue)with the presence of H_(2)O_(2).Interestingly,the addition of low concentration of norfloxacin can accelerate the color reaction process of TMB,and blue deepening of the solution can be observed with the naked eye.However,after adding high concentration of norfloxacin,the activity of nanozymewas inhibited,resulting in the gradual fading of the solution.Based on this principle,a colorimetric sensor integrated with smartphone RGB mode was established.The visual sensor exhibited good linearity for norfloxacin monitoring in the range of 0.13-2.51μmol/L and 17.5-100μmol/L.The limit of visual detectionwas 0.08μmol/L.In the actualwater sample analysis,the spiked recoveries of norfloxacin were over the range of 95.7%-104.7%.These results demonstrated that the visual sensor was a convenient and fast method for the efficient and accurate detection of norfloxacin in water,which may have broad application prospect.
基金Tianjin University's 985 Talent Plan, Key Project Science and Technology from Zhongyuan Oil Field and National Natural Science Foundation of China (50479070).
文摘A new method for visualizing sound propagation in solids and liquids is described in this paper. The method can show the sound propagation process dynamically in two dimensions. Compared with Schlieren method and dynamic photo-elastic method, this method cannot only show the sound field distribution in liquid and solid at different time moments, but also can be applied to non-transparent solid. In addition, it does not strictly require small residual stress of the sample. The sample can, therefore, be easily made. Because the acoustic field is obtained by indirect measurements, the recording can be affected by the after-shock of the receiving sensor and is prone to the influence of the direct wave of the liquid. Putting an aluminum plate into a liquid, we recorded the compression wave, shear wave and surface wave in the aluminum and, in the liquid we also recorded the direct wave and three head waves, which are directly coupled with the compression wave, shear wave and surface wave respectively. The recording clearly depicts the coupling relationship of the sound waves through the interface between the aluminum and the liquid. Putting a plexiglass into a liquid, we also recorded the sound waves in the plexiglass and the coupling relationship between the sound waves in the two mediums.
基金Supported by the National Basic Research Program of China under Grant No 2014CB340102
文摘To overcome the shortcomings of the traditional passive ranging technology based on image, such as poor ranging accuracy, low reliability and complex system, a new visual passive ranging method based on re-entrant coaxial optical path is presented. The target image is obtained using double cameras with coaxial optical path. Since there is imaging optical path difference between the cameras, the images are different. In comparison of the image differences, the target range could be reversed. The principle of the ranging method and the ranging model are described. The relationship among parameters in the ranging process is analyzed quantitatively. Meanwhile,the system composition and technical realization scheme are also presented. Also, the principle of the method is verified by the equivalent experiment. The experimental results show that the design scheme is correct and feasible with good robustness. Generally, the ranging error is less than 10% with good convergence. The optical path is designed in a re-entrant mode to reduce the volume and weight of the system. Through the coaxial design,the visual passive range of the targets with any posture can be obtained in real time. The system can be widely used in electro-optical countermeasure and concealed photoelectric detection.
基金supported by the Natural Science Foundation of China under Project 41076115the Global Change Research Program of China under project 2012CB955603the Public Science and Technology Research Funds of the Ocean under project 201005019
文摘The study of marine data visualization is of great value. Marine data, due to its large scale, random variation and multiresolution in nature, are hard to be visualized and analyzed. Nowadays, constructing an ocean model and visualizing model results have become some of the most important research topics of ‘Digital Ocean'. In this paper, a spherical ray casting method is developed to improve the traditional ray-casting algorithm and to make efficient use of GPUs. Aiming at the ocean current data, a 3D view-dependent line integral convolution method is used, in which the spatial frequency is adapted according to the distance from a camera. The study is based on a 3D virtual reality and visualization engine, namely the VV-Ocean. Some interactive operations are also provided to highlight the interesting structures and the characteristics of volumetric data. Finally, the marine data gathered in the East China Sea are displayed and analyzed. The results show that the method meets the requirements of real-time and interactive rendering.
文摘目的探究抗菌包装领域研究的发展、研究热点及未来发展趋势,推动抗菌包装的发展。方法运用知识图谱与文献计量分析法,使用可视化分析软件CiteSpace对中国知网(CNKI)和Web of Science(WOS)数据库中2000—2024年抗菌包装领域的文献进行可视化分析。结论相关文献的年发文量在整体上呈现出增长的趋势,尤其是英文文献的发文量增加显著;中文文献的研究成果在期刊分布上更为集中,外文文献则更为分散且学科覆盖更广;作者合作网络较为松散,其中国际的合作分化更为显著;通过对关键词分析显示,目前对抗菌包装的研究热点主要聚焦于抗菌材料、抗菌性能、食品保鲜应用,在未来的抗菌包装的研究中,抗菌包装的性能、新型抗菌成分与材料的开发和微观机制仍是主要研究热点,同时智能包装如环境响应型抗菌材料的研究、利用可生物降解材料与抗菌剂协同开发绿色抗菌材料将是未来的研究趋势。
