Objective:To conduct a visual analysis of the current status and hotspots of adolescent obesity research based on CiteSpace,to provide evidence-based basis for research directions and ideas in this field.Methods:This ...Objective:To conduct a visual analysis of the current status and hotspots of adolescent obesity research based on CiteSpace,to provide evidence-based basis for research directions and ideas in this field.Methods:This study used subject words and free words to retrieve literature from China National Knowledge Infrastructure,Wanfang Database,and VIP Core database.The retrieval time was from January 1,2010 to December 31,2024.CiteSpace6.3.R2 software was used to perform cluster sub-visualization analysis of the number of articles,authors,and keywords of literature on adolescent obesity.Results:A total of 523 Chinese articles were included.Since 2010,the number of articles on adolescent obesity in China showed an increasing trend,with an average annual growth rate of 12.3%.From the perspective of spatial distribution,more regions,institutions,and researchers have begun to pay attention to the research in this field,exploring the impact of dietary imbalance and insufficient exercise on adolescent obesity in different regions and the management methods.From the perspective of cooperation,the cooperation of various regions and institutions showed the characteristics of regional concentration or professional concentration,mainly distributed in medicine and physical education.High-frequency keywords included“living standard”,“exercise intervention”,“physical activity”,“mental health”,“body fat rate”,and“body fat rate”.After 2020,“intelligent weight management platform”and“remote follow-up”emerged to reflect the deep integration of technology and health management.Keyword cluster analysis showed that research hotspots focused on the etiological mechanism of obesity,intervention models,regional characteristics in different regions,and the risk of obesity-related metabolic diseases.With the launch of the national“Weight Management Year”initiative,research has been tilted to community health promotion and multi-sectoral collaboration,focusing on obesity prevention of preschool children and AI-driven personalized intervention programs[1].However,there is a bottleneck of lack of tracking mechanisms for long-term effects such as adolescent development and metabolic adaptability.Conclusions:The research status and hotspots of adolescent obesity have gradually shifted from early etiological exploration to precise intervention models driven by technology empowerment.In the future,researchers can build an obesity prevention and control network covering the whole life cycle and the whole region through the three-dimensional drive of“technological innovation×policy empowerment×disciplinary integration”,and eventually achieve the goal of reducing the obesity rate in adolescents.展开更多
Objective:To conduct a visual analysis of the current status and hotspots in the postoperative nursing of ureterocutaneostomy based on CiteSpace,in order to provide an evidence-based basis for the research direction a...Objective:To conduct a visual analysis of the current status and hotspots in the postoperative nursing of ureterocutaneostomy based on CiteSpace,in order to provide an evidence-based basis for the research direction and thinking in this field.Methods:In this study,the subject words and free words were used to search the China National Knowledge Infrastructure(CNKI),Wanfang Database,VIP Database,and Web of Science Core Database as the literature sources.The search time limit was from January 1,1999 to December 31,2024.CiteSpace 6.3.R2 software was used to conduct a visual analysis of the publication volume,authors,and keyword clusters of the literature related to ureterocutaneostomy nursing.Results:A total of 129 Chinese literary works were finally included.The results showed that 2019 was the peak year of publication volume(20 domestic articles);the First Affiliated Hospital of Nanchang University was the institution with the highest publication volume(13 articles);the high-frequency keywords included“bladder cancer”(42 times),“nursing”(29 times),and“quality of life”(16 times);the keyword cluster analysis showed that the research hotspots were concentrated in complication management,continuous nursing,and the application of intelligent technology.Conclusion:The nursing of ureterocutaneostomy has developed from a single technical operation to a multi-dimensional comprehensive intervention system,and the nursing shows a trend of multidisciplinary integration.In the future,it is necessary to strengthen the research and development of intelligent technology,the promotion of standardized nursing processes,and the balanced allocation of regional resources.展开更多
Objective To analyze the current research status and development trend of active surveillance of drug safety in China,and to provide reference and suggestions for future research.Methods Using bibliometric methods and...Objective To analyze the current research status and development trend of active surveillance of drug safety in China,and to provide reference and suggestions for future research.Methods Using bibliometric methods and with the help of the CiteSpace 6.1.R6,the literature on active surveillance of drug safety in CNKI from 2010 to 2022 was visualized and analyzed in terms of authors,institutions and keywords.Results and Conclusion The research on active surveillance of drug safety in China started late and is in a stable development period.Some Chinese scholars have done more work on active surveillance of drug safety.Additionally,a number of institutions have published some articles and surveillance objects,surveillance methods,and surveillance results are the main research content.However,the cross-institutional cooperation is not close.The traditional Chinese medicine injection,centralized surveillance,and automatic surveillance are the hot spots of research.It is the latest research frontier to use the Chinese hospital pharmacovigilance system to actively monitor drug safety.At present,the research related to active surveillance of drug safety in China is still in the early stage,and more in-depth research is needed to follow up.展开更多
AIM:To provide a comprehensive review of the advances in research on diabetes-associated dry eye(DADE),highlighting its pathophysiological mechanisms,risk factors,and demographic characteristics,laying the foundation ...AIM:To provide a comprehensive review of the advances in research on diabetes-associated dry eye(DADE),highlighting its pathophysiological mechanisms,risk factors,and demographic characteristics,laying the foundation for further investigation into its pathogenesis and treatment strategies.METHODS:A systemic review of the documents related to DADE had been performed based on the Web of Science database prior to achieving the plain text files of authors,titles,journals,and abstracts which afterwards had been imported into Citespace and VOSviewer software for data cleansing.The visual analysis was implemented from the following aspects:journals’publications,author and national cooperation,keyword co-occurrence,timeline analysis,and burst detection.RESULTS:The 318 documents in 167 journals had been incorporated with the overall annual citations and annual publications respectively growing significantly since 2014 and 2016.The keyword co-occurrence networks formed 4 clusters,with the representative keywords being dry eye,diabetes mellitus,prevalence,and diabetic retinopathy.Both the timeline map and the burst detection demonstrated that in the exploration of the pathogenesis of DADE,initial research was dedicated to Sjögren’s syndrome,followed by cross-sectional statistical analysis of the pertinent contributing factors of DADE using online databases.Precisely the oxidative stress seemed to surge into the research spotlight presently.The key pathogenic mechanisms of DADE include inflammation,oxidative stress and corneal neuropathy,contributing to the development of dry eye symptoms.CONCLUSION:Age,gender,diabetes duration,and diabetic retinopathy are strongly associated with the development of DADE,but the impact of other systemic factors require further investigation.With high prevalence of dry eye in Asia,valuable resources like the Korea National Health and Nutrition Examination Survey(KNHANES)database offer crucial data for developing risk prediction models for DADE.Building risk prediction models using machine learning algorithms is a promising future research direction,enabling physicians to identify high-risk individuals and implement early interventions.展开更多
Under the trend of economic globalization,the importance of supply chains has gradually become prominent,especially with the transformation and upgrading of China’s industrial chains in recent years.Supply chain tran...Under the trend of economic globalization,the importance of supply chains has gradually become prominent,especially with the transformation and upgrading of China’s industrial chains in recent years.Supply chain transformation has emerged as a significant focus of current academic research,and the construction of smart supply chains represents an inevitable development trend.This paper utilizes 1,051 research articles on smart supply chains published in core journals on China National Knowledge Infrastructure(CNKI)from 2014 to 2024 as the data source.It analyzes the literature data using CiteSpace software,visually exploring and revealing the frontiers and hotspots of domestic research on smart supply chains.The data analysis reveals that academic research in this field is at a stage of steady and healthy development.Domestic research trends include the cooperative mechanisms of smart supply chains in manufacturing,the operational mechanisms of smart supply chains in agriculture,and systematic research on influencing factors of smart supply chains.展开更多
AIM:To gain insight into the future research directions in scleral contact lenses(SCLs)through a comprehensive bibliometrics study.METHODS:The publications related to SCLs were screened from the Web of Science Core Co...AIM:To gain insight into the future research directions in scleral contact lenses(SCLs)through a comprehensive bibliometrics study.METHODS:The publications related to SCLs were screened from the Web of Science Core Collection(WOSCC)database.All bibliographic information was extracted and used to conduct a performance analysis.CiteSpace and VOSviewer were employed to visualize annual publication counts,journals,authors,countries,institutions,collaboration networks,keywords,and references.RESULTS:A total of 498 articles were included in our analysis and the number of publications about SCLs showed a significant yearly increase.These publications predominantly emanated from 523 institutions across 38 countries,with the United States and Australia leading in frequency.Totally 1361 authors were identified,among whom Vincent J.Stephen exhibited the highest number of publications,while Jacobs S.Deborah received the most citations.Notably,the journal Contact Lens&Anterior Eye emerged as the primary publisher of studies,and it also boasted the highest citation rate.“Fluid-ventilated,gas-permeable scleral contact lens is an effective option for managing severe ocular surface disease and many corneal disorders that would otherwise require penetrating keratoplasty”was the most cited paper published in eye&contact lens in 2005.The most prevalent keywords encompassed“keratoconus”,“scleral contact lenses”,“management”,“contact lenses”,“scleral contact lens”,“ocular surface disease”,“dry eye”,and“contact lens”.CONCLUSION:Although SCLs have demonstrated significant potential in ophthalmological care,the results offer valuable insights pertinent to future research directions and clinical practice.Greater emphasis should be placed on developing enhancements in design,materials,and fitting technique,as well as on reducing the complications associated with SCLs.展开更多
Objective:This study aims to analyze the research hotspots and trends in nursing care for children with Kawasaki disease.Methods:The study utilized the CiteSpace 6.1.R6 software to visualize nursing-related research o...Objective:This study aims to analyze the research hotspots and trends in nursing care for children with Kawasaki disease.Methods:The study utilized the CiteSpace 6.1.R6 software to visualize nursing-related research on Kawasaki disease in children,drawing from articles published in the CNKI and Web of Science core collection databases from January 1,2014,to January 1,2024.Key analysis components included authors,institutions,and keywords,supported by the creation of a corresponding knowledge map.Results:Literature Publications:Over the past decade,the analysis encompassed a total of 309 Chinese articles on nursing care for children with Kawasaki disease,with an average annual publication rate of 30.9 articles.Additionally,251 foreign language articles were scrutinized,exhibiting an average annual publication rate of 25.1 articles.Author and Institution Analysis:In Chinese literature,the notable figure of Huang Rimei emerged as a prolific author,with the Children's Hospital Affiliated with Zhengzhou University standing out as a high-yielding institution.Conversely,in English literature,the prolific authors Burns and Jane C were prominent,alongside the University of California,San Diego,which emerged as a high-yielding institution.Keyword and Research Hotspots Analysis:The focal points of research in Chinese literature revolved around continuous nursing,cardiovascular complications,clinical nursing pathways,rehabilitation effects,holistic nursing,and gamma globulin.Conversely,English literature emphasized research hotspots such as cardiovascular complications,treatment modalities,diagnostic approaches,long-term management strategies,gamma globulin therapy,steroid pulse therapy,and pediatric multisystem inflammatory syndrome.Conclusions:The quantity of Chinese literature concerning nursing care for children with Kawasaki disease appears comparatively scant,underscored by an uneven distribution of issuing institutions and a lack of influence.To address this,future endeavors should prioritize bolstering collaboration across diverse regions and institutions,conducting multi-center,cross-regional research,implementing clinical nursing pathways,and augmenting the continuity of care.Conversely,the upsurge in English literature publications regarding nursing care for children with Kawasaki disease signals a burgeoning interest,primarily concentrated on treatment modalities.This trend advocates for the integration of medical and nursing care and emphasizes the importance of remaining abreast of advancements in managing Kawasaki disease in children.展开更多
Background: Scar contractions caused by hand burns seriously impact both the function and appearance of the hand.Consequently,post-burn hand reconstruction is a primary focus of secondary reconstructive surgery perfor...Background: Scar contractions caused by hand burns seriously impact both the function and appearance of the hand.Consequently,post-burn hand reconstruction is a primary focus of secondary reconstructive surgery performed within the first 10 years after a burn injury.This study aimed to identify developmental trends and research hotspots in post-burn hand reconstruction,providing insights and recommendations for researchers.Methods: Bibliometric and visualization analyses were conducted using Cite Space v6.4.R1(64-bit) and VOS viewer.The Web of Science Core Collection served as the data source.A total of 136 articles between 1997 and2025 were included based on the following keywords: “postburn hand reconstruction” or “postburn hand” or“scar contraction hand deformity.”Results: The field of post-burn hand reconstruction is advancing,as indicated by the overall and annual increase in publications.The United States leads in number of published papers.However,major institutions show low centrality,indicating weak collaboration between countries and regions,with research still dominated by singlecenter studies.The top three most prolific authors were Paul P M van Zuijlen,Fatih Uyghur,and Ersin Uyghur.The keywords “double Z-plasty” and the cluster “flap” not only have high emergence intensity but also appear frequently in recent studies,marking them as current research hotspots.Conclusion: The lack of long-term research and consensus limits further advancements in post-burn hand reconstruction.To address this,multi-center and multi-disciplinary collaborations should be encouraged.Additionally,integrating basic medical research with biomedical engineering could enhance the management and outcomes of post-burn hand reconstruction.展开更多
BACKGROUND Mesenchymal stem cells(MSCs)are capable of self-renewal and differentiation,and extensive studies have demonstrated their therapeutic potential in atherosclerosis(AS).AIM To conduct a bibliometric analysis ...BACKGROUND Mesenchymal stem cells(MSCs)are capable of self-renewal and differentiation,and extensive studies have demonstrated their therapeutic potential in atherosclerosis(AS).AIM To conduct a bibliometric analysis of studies on the use of MSC therapy for AS over the past two decades,assess key trends and provide insights for future research directions.METHODS We systematically searched the Web of Science Core Collection database for articles published between 1999 and 2023,yielding a total of 556 articles.Visual representation and bibliometric analysis of information and trends were facilitated using CiteSpace,the R package‘bibliometrix’and VOSviewer.RESULTS The analyzed articles were predominantly from 52 countries/regions,with prominent contributions from China and the United States.A cohort of 3057 authors contributed to these publications,with the works of Libby P distinguished by their influence and citation count.Int J Mol Sci has emerged as the journal with the highest publication volume,prominently disseminating influential papers and identifying citation outbreaks.Furthermore,our analysis identified current research hotspots within the field,focusing on vascular progenitor cells,inflammatory mechanisms,and extracellular vesicles.Emerging research frontiers,such as extracellular vesicles and oxidative stress,have been highlighted as areas of burgeoning interest.Finally,we offer perspectives on the status of research and future directions of MSC therapy in AS.CONCLUSION This comprehensive analysis provides valuable insights for advancing scientific research on MSC therapy for AS.By elucidating pivotal trends and research directions,this study aimed to foster innovation and promote the progress of disciplines in this field,thereby contributing to advancing scientific knowledge and clinical practice.展开更多
The Chinese traditional medicine,agarwood,is a commonly used medicine for regulating qi,which has many clinical applications because of its unique curative effect.In this study,CiteSpace software was used to visually ...The Chinese traditional medicine,agarwood,is a commonly used medicine for regulating qi,which has many clinical applications because of its unique curative effect.In this study,CiteSpace software was used to visually analyze the application and development trend of agarwood in the literature from CNKI website in the period of 2007-2022.The analysis results showed that the research on agarwood has basically formed core groups of authors,and universities and their affiliated hospitals are main publishing institutions.Moreover,in this study,several research directions of agarwood were also summarized,including clinical research,chemical composition,structural identification and quality standards,showing that agarwood has rich and flexible application prospects in many aspects.On this basis,several suggestions were put forward:strengthening the cooperation between universities and research institutes and building a scientific research cooperation community,and promoting the combination of clinical research and laboratory research.展开更多
[Objectives]This study was conducted to explore the application and development trend of Chinese medicinal material cinnamon in the field of traditional Chinese medicine.[Methods]Articles published from 2008 to 2023 w...[Objectives]This study was conducted to explore the application and development trend of Chinese medicinal material cinnamon in the field of traditional Chinese medicine.[Methods]Articles published from 2008 to 2023 were exported using"cinnamon"as the subject word in the Chinese database of CNKI.Knowledge graphs were drawn by CiteSpace software on the number of articles published,the institutions publishing articles,and keyword clustering,and the data were sorted by Excel.Combined with the extracted information,the application of cinnamon in traditional Chinese medicine and integrated traditional Chinese and Western medicine was analyzed,and its development trend was discussed and prospected,providing further reference for researchers.[Results]The number of articles published showed an overall upward trend and maintained a high number of articles.In the analysis of the journals publishing articles,the journal with the largest number of articles was West China Journal of Pharmaceutical Sciences,which had certain representativeness.In the analysis of institutions publishing articles,the institution with the largest number of articles was Beijing University of Chinese Medicine,and most institutions had little cooperation.Four categories was obtained in keyword clustering,respectively,general research,component identification,production process and product development of cinnamon."Glycyrrhizin"was the keyword with the earliest burst time,and the hot words that have received much attention in recent years are"medication law"and"data mining".[Conclusions]The application of cinnamon in the field of traditional Chinese medicine is mainly to treat diseases and as raw materials for traditional Chinese medicine products.The development trend is"quality control"and"product research and development".Further research and development of cinnamon in traditional Chinese medicine need to promote the participation of more institutions to participate,and cooperation and communication between institutions should be strengthened to promote the deep integration of production,research and academia.展开更多
Objective:To explore the development and hotspots in the field of traditional Chinese medicine(TCM)constitution identification since the year 2000.Methods:Using CiteSpace and VOSviewer software,literature from five pr...Objective:To explore the development and hotspots in the field of traditional Chinese medicine(TCM)constitution identification since the year 2000.Methods:Using CiteSpace and VOSviewer software,literature from five prominent databases including VIP,WanFang,China National Knowledge Infrastructure(CNKI),PubMed,and Web ofScience was analyzed.Visual methods were used to examine the annual publications,keywords,authors,and collaborative networks.Results:After deduplication with EndNotes,a total of 5,747 articles meeting the criteria were included.Since 2000,the publications of TCM constitution identification shown three major stages:a significant increasing trend with the year before 2016,a fluctuating trend from 2016 to 2021,and a decreasing trend with the year after 2021.The co-occurrence analysis ofkeywords revealed health management,hypertension,and constitution as hot directions in this field of research.CiteSpace was used for keyword clustering and burst analysis,health management,medical life,and constitution emerged as the latest hotspots in the past three years,which will be the main development directions in the future.Clusters such as hypertension,preventive treatment,and health management were identified,representing the main research themes at present.VOSviewer and CiteSpace were used for co-occurrence and clustering analysis of authors,revealing collaborative research networks,with prominent groups represented by WANG Qi,WANG Ji,LI Lingru,HOU Shujuan,ZHU Yanbo,etc.Conclusion:Research related to TCM constitution identification is developing rapidly,involving various aspects of medical care and daily life.However,there is still a need to build an extensive academic platform,strengthen the dissemination of Chinese medicine culture,standardize,intellectualize and universalize the identification of TCM constitution assessments,and construct a health service system with Chinese characteristics.展开更多
Objective:The purpose of this study is to use CiteSpace software to examine the development patterns and hotspots in post-stroke hemiplegia research during the last 20 years.Methods:Articles about post-stroke hemipleg...Objective:The purpose of this study is to use CiteSpace software to examine the development patterns and hotspots in post-stroke hemiplegia research during the last 20 years.Methods:Articles about post-stroke hemiplegia from January 2005 to December 2024 were analyzed in the Web of Science database.CiteSpace software was used to conduct co-citation analysis of the articles about post-stroke hemiplegia as well as cooperative network analyses of authors,countries,and institutions,as well as keyword co-occurrence,clustering,emergence,and time line analyses.The results were displayed in a visual atlas.Result:A total of 2625 papers were obtained,and there were more publications overall.China and the United States had the most number of articles,while Chae,John was the author with the most number of articles.Capital Med University and Ohio State University had the most articles among their agencies.The keywords"stroke"and"rehabilitation"were used the most.The key word analysis indicates that the present study focus is on exercise rehabilitation measures and post-stroke treatment.Conclusion:Using CiteSpace software to analyze the literature on post-stroke hemiplegia,it is discovered that the use of new technologies in the field of mechanical thrombectomy and the effectiveness of rehabilitation techniques like mirror treatment are the key areas of study attention.This study has positive significance for finding safer and more effective treatments for post-stroke hemiplegia.展开更多
Stem cells have been confirmed to be involved in the occurrence and development of diabetic retinopathy;however,the underlying mechanisms remain unclear.In this study,we used Citespace software to visually analyze 552...Stem cells have been confirmed to be involved in the occurrence and development of diabetic retinopathy;however,the underlying mechanisms remain unclear.In this study,we used Citespace software to visually analyze 552 articles exploring the stem cell-based treatment of diabetic retinopathy over the past 20 years,which were included in the Web of Science Core Collection.We found the following:(1)a co-citation analysis of the references cited by all 552 articles indicated 15 clusters.In cluster#0,representing the stem cell field,some highly cited landmark studies emerged between 2009–2013.For example,endothelial progenitor cells and diabetic retinopathy gradually received the full attention of scholars,in terms of their relationship and therapeutic prospects.Some researchers also verified the potential of adipose-derived stem cells to differentiate into stable retinal perivascular cells,using a variety of animal models of retinal vascular disease.All of these achievements provided references for the subsequent stem cell research.(2)An analysis of popular keywords among the 552 articles revealed that,during the past 20 years,a relative increase in basic research articles examining stem cells and endothelial progenitor cells for the treatment of diabetic retinopathy was observed.The contents of these articles primarily involved the expression of vascular endothelial growth factor,vascular regeneration,oxidative stress,and inflammatory response.(3)A burst analysis of keywords used in the 552 articles indicated that genetic and cytological research regarding the promotion of angiogenesis was an issue of concern from 2001 to 2012,including several studies addressing the expression of various growth factor genes;from 2014 to 2020,mouse models of diabetic retinopathy were recognized as mature animal models,and the most recent research has focused on macular degeneration,macular edema,neurodegeneration,and inflammatory changes in diabetic animal models.(4)Globally,the current authoritative studies have focused on basic research towards the stem cell treatment of diabetic retinopathy.Existing clinical studies are of low quality and have insufficient evidence levels,and their findings have not yet been widely accepted in clinical practice.Major challenges during stem cell transplantation remain,including stem cell heterogeneity,cell delivery,and the effective homing of stem cells to damaged tissue.However,clinical trials examining potential stem cell-based treatments of diabetic retinopathy,including the use of pluripotent stem cells,retinal pigment epithelial cells,bone marrow mesenchymal stem cells,and endothelial progenitor cells,are currently ongoing,and high-quality clinical evidence is likely to appear in the future,to promote clinical transformation.展开更多
Objective:The objective of this study is to explore the current situation,clinical research hot spots,and trends of traditional Chinese medicine(TCM)nursing technology in rheumatoid arthritis(RA),to draw a panorama of...Objective:The objective of this study is to explore the current situation,clinical research hot spots,and trends of traditional Chinese medicine(TCM)nursing technology in rheumatoid arthritis(RA),to draw a panorama of clinical research,to provide the basis and clues for subsequent high-level evidence integration and further in-depth research.Materials and Methods:Seven databases including China National Knowledge Infrastructure,Chinese Scientific Journal Database(VIP),Wanfang Database,Chinese Biomedical Literature Database(Sino-Med),PubMed,Embase,and the Cochrane Library were searched.The bibliometric method and visualization software CiteSpace were used to conduct a multi-dimensional analysis of the included literature.Results:A total of 805 pieces of literature were included(of them,one was written in German and four in English),and the number of published literature showed an increasing trend year by year.There were only 30(3.73%)pieces of literature published in nursing journals.The hot spots of the co-occurrence map were concentrated in:(1)the nursing of fumigation in RA;(2)the efficacy evaluation of TCM nursing technology on pain,joint malformation,and joint dysfunction caused by RA.The included literature themes focused on five TCM technologies:fumigation,moxibustion,acupoint patching,acupoint injection,and Chinese herbal soaking.The beginning year and strength in TCM fumigation were 2012 and 5.2,and those in moxibustion were 2011 and 3.38.Conclusion:The related studies are on the rise.It has entered the field of international readers with clear research hot spots.However,there are still shortcomings such as little literature published in Chinese nursing core journals,few non-Chinese-related documents,and a lack of international exchanges and cooperation.The current research hot spots in this field are TCM fumigation,and the cutting-edge trend of future research may be fumigation and moxibustion technology.It is suggested that further research can focus on evidence integration and original research on the self-optimization of these two techniques.展开更多
[Objectives]Based on the related literature of benefit finding in China National Knowledge Infrastructure(CNKI),this paper analyzes the research status,hot spots and trends in this field.[Methods]To search for the rel...[Objectives]Based on the related literature of benefit finding in China National Knowledge Infrastructure(CNKI),this paper analyzes the research status,hot spots and trends in this field.[Methods]To search for the related literature on benefit finding in China National Knowledge Infrastructure(CNKI),and use Citespace software to visually analyze the number of papers,authors,institutions and keywords.[Results]A total of 204 related papers were obtained,and the annual number of published papers showed a gradual increasing trend.The authors of published papers were represented by Zhang Fenglan,Liu Zhunzhun and Zhang Ting,and the Nursing College of Anhui Medical University published the most papers.The research focus was on social support,coping method and other influencing factors,and qualitative research was the main research type.The key population was breast cancer,stroke patients and their caregivers,and the development trend focused on reliability and validity test and correlation analysis.[Conclusions]The field of benefit finding in China is in the initial exploration stage,and there is little cooperation and exchange between authors and institutions.In the future,academic exchanges and multidisciplinary assistance should be strengthened to promote the rapid development of this field.展开更多
Objective Through bibliometrics and visual analysis of the related studies on traditional Chinese medicine(TCM)treatment of immune thrombocytopenia(ITP),this study aims to sort out the overall research progress,hotspo...Objective Through bibliometrics and visual analysis of the related studies on traditional Chinese medicine(TCM)treatment of immune thrombocytopenia(ITP),this study aims to sort out the overall research progress,hotspots,and trends in this field,and provide reference for further research in ITP.Methods The articles on ITP treated by TCM were retrieved from China National Knowledge Infrastructure(CNKI),Wanfang Database,China Science and Technology Journal Database(VIP),Web of Science Core Collection(WOSCC),and PubMed.The retrieval time was from the establishment of the databases to July 31,2022.VOSviewer,CiteSpace,Carrot2,and Note-Express were used for data analysis of the articles in terms of their quantities,types,and journals,and for visualization of research hotspots,authors,institutions,and keywords.Results 1493 Chinese articles and 40 English articles were included.The articles in Chinese mainly focus on clinical trial research and clinical experience summary,while the English articles mainly focus on clinical trial research and animal research.The Chinese articles were published in 317 Chinese journals,while English articles were published in 29 English journals.Research hotspots include the clinical syndrome differentiation of ITP,the therapeutic effect of TCM compounds on ITP,and the mechanism of ITP treatment.Keyword analysis shows that there are many research achievements in integrated traditional Chinese and western medicine treatment,clinical research,famous doctors’experience,TCM treatment,cellular immunity,and humoral immunity.The authors with the most articles in Chinese and English are Professor CHEN Xinyi and Professor MA Rou,respectively,and the research institutions with the most articles are Dongzhimen Hospital of Beijing University of Chinese Medicine and Xiyuan Hospital of China Academy of Chinese Medical Sciences.Chinese herbs often used to treat ITP clinically include Xianhecao(Agrimoniae Herba),Nvzhenzi(Ligustri Lucidi Fructus),Mohanlian(Ecliptae Herba),Zhongjiefeng(Sarcandrae Herba),etc.,and the prescription usually used to treat ITP include Guipi Decoction(归脾汤),Xijiao Dihuang Decoction(犀角地黄汤),Bazhen Decoction(八珍汤),Erzhi Pill(二至丸),and Xiaochaihu De-coction(小柴胡汤).The main development trends toward retrospective study,TCM treatment mechanism,and data mining.展开更多
It is difficult to analyze the inter-relationship for the construction layout of a reservoir project scientifically and intuitively.According to the characteristics of broad field and huge information,the modeling met...It is difficult to analyze the inter-relationship for the construction layout of a reservoir project scientifically and intuitively.According to the characteristics of broad field and huge information,the modeling methods of digital terrain and solid model as well as the techniques of texture mapping and scene navigation are adopted.The simulation system is developed by C program language,which includes the functions of the interactive navigation of 3D scene,the visual inquiry of project digital model information,the storage and management of project information.A certain reservoir is taken as a case.The 3D visual analysis for the construction layout and engineering information are obtained.The proposed system is of great advantages in dealing with large amount of information and the method provides a theoretical basis and technical support for the construction layout of a reservoir project.展开更多
Background With the development of information technology,there is a significant increase in the number of network traffic logs mixed with various types of cyberattacks.Traditional intrusion detection systems(IDSs)are...Background With the development of information technology,there is a significant increase in the number of network traffic logs mixed with various types of cyberattacks.Traditional intrusion detection systems(IDSs)are limited in detecting new inconstant patterns and identifying malicious traffic traces in real time.Therefore,there is an urgent need to implement more effective intrusion detection technologies to protect computer security.Methods In this study,we designed a hybrid IDS by combining our incremental learning model(KANSOINN)and active learning to learn new log patterns and detect various network anomalies in real time.Conclusions Experimental results on the NSLKDD dataset showed that KAN-SOINN can be continuously improved and effectively detect malicious logs.Meanwhile,comparative experiments proved that using a hybrid query strategy in active learning can improve the model learning efficiency.展开更多
[Objectives]To analyze the current research situation,hotspots and trends of curcumin and diabetes in recent 10 years.[Methods]Web of Science database was set as data source,the annual number of papers,the distributio...[Objectives]To analyze the current research situation,hotspots and trends of curcumin and diabetes in recent 10 years.[Methods]Web of Science database was set as data source,the annual number of papers,the distribution of authors,the distribution of country/institution,the distribution of journals,the distribution of key words in the literature about curcumin and diabetes from January 1,2010 to March 31,2021 were quantitatively and visually analyzed with the aid of visualization software Bibliometrix.[Results]A total of 475 articles were included,and the annual number of papers was on the rise;the top three high-yielding countries were China(120 papers),India(65 papers),and the United States(58 papers).In terms of international cooperation,China and the United States had the most cooperation(27 papers);the top three high-yielding institutions were Wenzhou Medical University(42 papers),Mashhad University of Medical Sciences(41 papers)and Tehran University of Medical Sciences(30 papers);the most frequently cited authors were Wang Y(19 times),Li X(13 times),Li Y(12 times),Liang G(12 times)and Zhang Y(12 times);the top three journals in number of papers were Diabetology&Metabolic Syndrome(8 papers),PLoS One(8 papers),and European Journal of Pharmacology(7 papers),and the h index was 7,8,and 6,respectively;the most frequently cited journals were Diabetes(496 times),Journal of Biological Chemistry(486 times),PLoS One(347 times),Diabetes Care(284 times),and European Journal of Pharmacology(229 times);the most frequent key words mainly included oxidative stress,curcumin,insulin-resistance and expression;the hotspots were insulin resistance and NF-κB,mainly focusing on in vitro experiments.[Conclusions]The curcumin has good therapeutic potential in improving insulin resistance,inhibiting inflammation and oxidative stress,etc.The results are expected provide a reference and basis for scientific researchers to understand the current situation of curcumin and diabetes research and carry out the further research.展开更多
文摘Objective:To conduct a visual analysis of the current status and hotspots of adolescent obesity research based on CiteSpace,to provide evidence-based basis for research directions and ideas in this field.Methods:This study used subject words and free words to retrieve literature from China National Knowledge Infrastructure,Wanfang Database,and VIP Core database.The retrieval time was from January 1,2010 to December 31,2024.CiteSpace6.3.R2 software was used to perform cluster sub-visualization analysis of the number of articles,authors,and keywords of literature on adolescent obesity.Results:A total of 523 Chinese articles were included.Since 2010,the number of articles on adolescent obesity in China showed an increasing trend,with an average annual growth rate of 12.3%.From the perspective of spatial distribution,more regions,institutions,and researchers have begun to pay attention to the research in this field,exploring the impact of dietary imbalance and insufficient exercise on adolescent obesity in different regions and the management methods.From the perspective of cooperation,the cooperation of various regions and institutions showed the characteristics of regional concentration or professional concentration,mainly distributed in medicine and physical education.High-frequency keywords included“living standard”,“exercise intervention”,“physical activity”,“mental health”,“body fat rate”,and“body fat rate”.After 2020,“intelligent weight management platform”and“remote follow-up”emerged to reflect the deep integration of technology and health management.Keyword cluster analysis showed that research hotspots focused on the etiological mechanism of obesity,intervention models,regional characteristics in different regions,and the risk of obesity-related metabolic diseases.With the launch of the national“Weight Management Year”initiative,research has been tilted to community health promotion and multi-sectoral collaboration,focusing on obesity prevention of preschool children and AI-driven personalized intervention programs[1].However,there is a bottleneck of lack of tracking mechanisms for long-term effects such as adolescent development and metabolic adaptability.Conclusions:The research status and hotspots of adolescent obesity have gradually shifted from early etiological exploration to precise intervention models driven by technology empowerment.In the future,researchers can build an obesity prevention and control network covering the whole life cycle and the whole region through the three-dimensional drive of“technological innovation×policy empowerment×disciplinary integration”,and eventually achieve the goal of reducing the obesity rate in adolescents.
基金Research Project of the First Affiliated Hospital of Shihezi University(HL202102)。
文摘Objective:To conduct a visual analysis of the current status and hotspots in the postoperative nursing of ureterocutaneostomy based on CiteSpace,in order to provide an evidence-based basis for the research direction and thinking in this field.Methods:In this study,the subject words and free words were used to search the China National Knowledge Infrastructure(CNKI),Wanfang Database,VIP Database,and Web of Science Core Database as the literature sources.The search time limit was from January 1,1999 to December 31,2024.CiteSpace 6.3.R2 software was used to conduct a visual analysis of the publication volume,authors,and keyword clusters of the literature related to ureterocutaneostomy nursing.Results:A total of 129 Chinese literary works were finally included.The results showed that 2019 was the peak year of publication volume(20 domestic articles);the First Affiliated Hospital of Nanchang University was the institution with the highest publication volume(13 articles);the high-frequency keywords included“bladder cancer”(42 times),“nursing”(29 times),and“quality of life”(16 times);the keyword cluster analysis showed that the research hotspots were concentrated in complication management,continuous nursing,and the application of intelligent technology.Conclusion:The nursing of ureterocutaneostomy has developed from a single technical operation to a multi-dimensional comprehensive intervention system,and the nursing shows a trend of multidisciplinary integration.In the future,it is necessary to strengthen the research and development of intelligent technology,the promotion of standardized nursing processes,and the balanced allocation of regional resources.
文摘Objective To analyze the current research status and development trend of active surveillance of drug safety in China,and to provide reference and suggestions for future research.Methods Using bibliometric methods and with the help of the CiteSpace 6.1.R6,the literature on active surveillance of drug safety in CNKI from 2010 to 2022 was visualized and analyzed in terms of authors,institutions and keywords.Results and Conclusion The research on active surveillance of drug safety in China started late and is in a stable development period.Some Chinese scholars have done more work on active surveillance of drug safety.Additionally,a number of institutions have published some articles and surveillance objects,surveillance methods,and surveillance results are the main research content.However,the cross-institutional cooperation is not close.The traditional Chinese medicine injection,centralized surveillance,and automatic surveillance are the hot spots of research.It is the latest research frontier to use the Chinese hospital pharmacovigilance system to actively monitor drug safety.At present,the research related to active surveillance of drug safety in China is still in the early stage,and more in-depth research is needed to follow up.
基金Supported by the Exploratory Project of The Second Affiliated Hospital of Xi’an Jiaotong University[No.2020YJ(ZYTS)154].
文摘AIM:To provide a comprehensive review of the advances in research on diabetes-associated dry eye(DADE),highlighting its pathophysiological mechanisms,risk factors,and demographic characteristics,laying the foundation for further investigation into its pathogenesis and treatment strategies.METHODS:A systemic review of the documents related to DADE had been performed based on the Web of Science database prior to achieving the plain text files of authors,titles,journals,and abstracts which afterwards had been imported into Citespace and VOSviewer software for data cleansing.The visual analysis was implemented from the following aspects:journals’publications,author and national cooperation,keyword co-occurrence,timeline analysis,and burst detection.RESULTS:The 318 documents in 167 journals had been incorporated with the overall annual citations and annual publications respectively growing significantly since 2014 and 2016.The keyword co-occurrence networks formed 4 clusters,with the representative keywords being dry eye,diabetes mellitus,prevalence,and diabetic retinopathy.Both the timeline map and the burst detection demonstrated that in the exploration of the pathogenesis of DADE,initial research was dedicated to Sjögren’s syndrome,followed by cross-sectional statistical analysis of the pertinent contributing factors of DADE using online databases.Precisely the oxidative stress seemed to surge into the research spotlight presently.The key pathogenic mechanisms of DADE include inflammation,oxidative stress and corneal neuropathy,contributing to the development of dry eye symptoms.CONCLUSION:Age,gender,diabetes duration,and diabetic retinopathy are strongly associated with the development of DADE,but the impact of other systemic factors require further investigation.With high prevalence of dry eye in Asia,valuable resources like the Korea National Health and Nutrition Examination Survey(KNHANES)database offer crucial data for developing risk prediction models for DADE.Building risk prediction models using machine learning algorithms is a promising future research direction,enabling physicians to identify high-risk individuals and implement early interventions.
文摘Under the trend of economic globalization,the importance of supply chains has gradually become prominent,especially with the transformation and upgrading of China’s industrial chains in recent years.Supply chain transformation has emerged as a significant focus of current academic research,and the construction of smart supply chains represents an inevitable development trend.This paper utilizes 1,051 research articles on smart supply chains published in core journals on China National Knowledge Infrastructure(CNKI)from 2014 to 2024 as the data source.It analyzes the literature data using CiteSpace software,visually exploring and revealing the frontiers and hotspots of domestic research on smart supply chains.The data analysis reveals that academic research in this field is at a stage of steady and healthy development.Domestic research trends include the cooperative mechanisms of smart supply chains in manufacturing,the operational mechanisms of smart supply chains in agriculture,and systematic research on influencing factors of smart supply chains.
文摘AIM:To gain insight into the future research directions in scleral contact lenses(SCLs)through a comprehensive bibliometrics study.METHODS:The publications related to SCLs were screened from the Web of Science Core Collection(WOSCC)database.All bibliographic information was extracted and used to conduct a performance analysis.CiteSpace and VOSviewer were employed to visualize annual publication counts,journals,authors,countries,institutions,collaboration networks,keywords,and references.RESULTS:A total of 498 articles were included in our analysis and the number of publications about SCLs showed a significant yearly increase.These publications predominantly emanated from 523 institutions across 38 countries,with the United States and Australia leading in frequency.Totally 1361 authors were identified,among whom Vincent J.Stephen exhibited the highest number of publications,while Jacobs S.Deborah received the most citations.Notably,the journal Contact Lens&Anterior Eye emerged as the primary publisher of studies,and it also boasted the highest citation rate.“Fluid-ventilated,gas-permeable scleral contact lens is an effective option for managing severe ocular surface disease and many corneal disorders that would otherwise require penetrating keratoplasty”was the most cited paper published in eye&contact lens in 2005.The most prevalent keywords encompassed“keratoconus”,“scleral contact lenses”,“management”,“contact lenses”,“scleral contact lens”,“ocular surface disease”,“dry eye”,and“contact lens”.CONCLUSION:Although SCLs have demonstrated significant potential in ophthalmological care,the results offer valuable insights pertinent to future research directions and clinical practice.Greater emphasis should be placed on developing enhancements in design,materials,and fitting technique,as well as on reducing the complications associated with SCLs.
基金Kunming Health Science and Technology Talent Cultivation Project(Project No.:2023-Cultivation Category-00)Health Research Project of Kunming Municipal Health Commission(Project No.:2022-14-04-006)。
文摘Objective:This study aims to analyze the research hotspots and trends in nursing care for children with Kawasaki disease.Methods:The study utilized the CiteSpace 6.1.R6 software to visualize nursing-related research on Kawasaki disease in children,drawing from articles published in the CNKI and Web of Science core collection databases from January 1,2014,to January 1,2024.Key analysis components included authors,institutions,and keywords,supported by the creation of a corresponding knowledge map.Results:Literature Publications:Over the past decade,the analysis encompassed a total of 309 Chinese articles on nursing care for children with Kawasaki disease,with an average annual publication rate of 30.9 articles.Additionally,251 foreign language articles were scrutinized,exhibiting an average annual publication rate of 25.1 articles.Author and Institution Analysis:In Chinese literature,the notable figure of Huang Rimei emerged as a prolific author,with the Children's Hospital Affiliated with Zhengzhou University standing out as a high-yielding institution.Conversely,in English literature,the prolific authors Burns and Jane C were prominent,alongside the University of California,San Diego,which emerged as a high-yielding institution.Keyword and Research Hotspots Analysis:The focal points of research in Chinese literature revolved around continuous nursing,cardiovascular complications,clinical nursing pathways,rehabilitation effects,holistic nursing,and gamma globulin.Conversely,English literature emphasized research hotspots such as cardiovascular complications,treatment modalities,diagnostic approaches,long-term management strategies,gamma globulin therapy,steroid pulse therapy,and pediatric multisystem inflammatory syndrome.Conclusions:The quantity of Chinese literature concerning nursing care for children with Kawasaki disease appears comparatively scant,underscored by an uneven distribution of issuing institutions and a lack of influence.To address this,future endeavors should prioritize bolstering collaboration across diverse regions and institutions,conducting multi-center,cross-regional research,implementing clinical nursing pathways,and augmenting the continuity of care.Conversely,the upsurge in English literature publications regarding nursing care for children with Kawasaki disease signals a burgeoning interest,primarily concentrated on treatment modalities.This trend advocates for the integration of medical and nursing care and emphasizes the importance of remaining abreast of advancements in managing Kawasaki disease in children.
文摘Background: Scar contractions caused by hand burns seriously impact both the function and appearance of the hand.Consequently,post-burn hand reconstruction is a primary focus of secondary reconstructive surgery performed within the first 10 years after a burn injury.This study aimed to identify developmental trends and research hotspots in post-burn hand reconstruction,providing insights and recommendations for researchers.Methods: Bibliometric and visualization analyses were conducted using Cite Space v6.4.R1(64-bit) and VOS viewer.The Web of Science Core Collection served as the data source.A total of 136 articles between 1997 and2025 were included based on the following keywords: “postburn hand reconstruction” or “postburn hand” or“scar contraction hand deformity.”Results: The field of post-burn hand reconstruction is advancing,as indicated by the overall and annual increase in publications.The United States leads in number of published papers.However,major institutions show low centrality,indicating weak collaboration between countries and regions,with research still dominated by singlecenter studies.The top three most prolific authors were Paul P M van Zuijlen,Fatih Uyghur,and Ersin Uyghur.The keywords “double Z-plasty” and the cluster “flap” not only have high emergence intensity but also appear frequently in recent studies,marking them as current research hotspots.Conclusion: The lack of long-term research and consensus limits further advancements in post-burn hand reconstruction.To address this,multi-center and multi-disciplinary collaborations should be encouraged.Additionally,integrating basic medical research with biomedical engineering could enhance the management and outcomes of post-burn hand reconstruction.
基金Supported by the Regional Cooperation Program of Shanxi Province,China,No.202204041101038the Construction and Demonstration of the Molecular Diagnosis and Treatment Platform for Vascular Diseases in Shanxi Province,China,No.SCP-2023-17Translational Medicine Engineering Research Center for Vascular Diseases of Shanxi Province,China,No.2022017.
文摘BACKGROUND Mesenchymal stem cells(MSCs)are capable of self-renewal and differentiation,and extensive studies have demonstrated their therapeutic potential in atherosclerosis(AS).AIM To conduct a bibliometric analysis of studies on the use of MSC therapy for AS over the past two decades,assess key trends and provide insights for future research directions.METHODS We systematically searched the Web of Science Core Collection database for articles published between 1999 and 2023,yielding a total of 556 articles.Visual representation and bibliometric analysis of information and trends were facilitated using CiteSpace,the R package‘bibliometrix’and VOSviewer.RESULTS The analyzed articles were predominantly from 52 countries/regions,with prominent contributions from China and the United States.A cohort of 3057 authors contributed to these publications,with the works of Libby P distinguished by their influence and citation count.Int J Mol Sci has emerged as the journal with the highest publication volume,prominently disseminating influential papers and identifying citation outbreaks.Furthermore,our analysis identified current research hotspots within the field,focusing on vascular progenitor cells,inflammatory mechanisms,and extracellular vesicles.Emerging research frontiers,such as extracellular vesicles and oxidative stress,have been highlighted as areas of burgeoning interest.Finally,we offer perspectives on the status of research and future directions of MSC therapy in AS.CONCLUSION This comprehensive analysis provides valuable insights for advancing scientific research on MSC therapy for AS.By elucidating pivotal trends and research directions,this study aimed to foster innovation and promote the progress of disciplines in this field,thereby contributing to advancing scientific knowledge and clinical practice.
基金Supported by Undergraduate Training Program for Innovation and Entrepreneurship of Guangxi University of Chinese Medicine (S202310600135S202310600049).
文摘The Chinese traditional medicine,agarwood,is a commonly used medicine for regulating qi,which has many clinical applications because of its unique curative effect.In this study,CiteSpace software was used to visually analyze the application and development trend of agarwood in the literature from CNKI website in the period of 2007-2022.The analysis results showed that the research on agarwood has basically formed core groups of authors,and universities and their affiliated hospitals are main publishing institutions.Moreover,in this study,several research directions of agarwood were also summarized,including clinical research,chemical composition,structural identification and quality standards,showing that agarwood has rich and flexible application prospects in many aspects.On this basis,several suggestions were put forward:strengthening the cooperation between universities and research institutes and building a scientific research cooperation community,and promoting the combination of clinical research and laboratory research.
基金Supported by Undergraduate Innovation and Entrepreneurship Training Program of Guangxi University of Chinese Medicine[S202310600049,S202310600135]Research Training Projects at Guangxi University of Chinese Medicine in 2022[2022DXS18,2022DXS19].
文摘[Objectives]This study was conducted to explore the application and development trend of Chinese medicinal material cinnamon in the field of traditional Chinese medicine.[Methods]Articles published from 2008 to 2023 were exported using"cinnamon"as the subject word in the Chinese database of CNKI.Knowledge graphs were drawn by CiteSpace software on the number of articles published,the institutions publishing articles,and keyword clustering,and the data were sorted by Excel.Combined with the extracted information,the application of cinnamon in traditional Chinese medicine and integrated traditional Chinese and Western medicine was analyzed,and its development trend was discussed and prospected,providing further reference for researchers.[Results]The number of articles published showed an overall upward trend and maintained a high number of articles.In the analysis of the journals publishing articles,the journal with the largest number of articles was West China Journal of Pharmaceutical Sciences,which had certain representativeness.In the analysis of institutions publishing articles,the institution with the largest number of articles was Beijing University of Chinese Medicine,and most institutions had little cooperation.Four categories was obtained in keyword clustering,respectively,general research,component identification,production process and product development of cinnamon."Glycyrrhizin"was the keyword with the earliest burst time,and the hot words that have received much attention in recent years are"medication law"and"data mining".[Conclusions]The application of cinnamon in the field of traditional Chinese medicine is mainly to treat diseases and as raw materials for traditional Chinese medicine products.The development trend is"quality control"and"product research and development".Further research and development of cinnamon in traditional Chinese medicine need to promote the participation of more institutions to participate,and cooperation and communication between institutions should be strengthened to promote the deep integration of production,research and academia.
基金supported by the National Natural Science Foundation of China Youth Program(81904324)。
文摘Objective:To explore the development and hotspots in the field of traditional Chinese medicine(TCM)constitution identification since the year 2000.Methods:Using CiteSpace and VOSviewer software,literature from five prominent databases including VIP,WanFang,China National Knowledge Infrastructure(CNKI),PubMed,and Web ofScience was analyzed.Visual methods were used to examine the annual publications,keywords,authors,and collaborative networks.Results:After deduplication with EndNotes,a total of 5,747 articles meeting the criteria were included.Since 2000,the publications of TCM constitution identification shown three major stages:a significant increasing trend with the year before 2016,a fluctuating trend from 2016 to 2021,and a decreasing trend with the year after 2021.The co-occurrence analysis ofkeywords revealed health management,hypertension,and constitution as hot directions in this field of research.CiteSpace was used for keyword clustering and burst analysis,health management,medical life,and constitution emerged as the latest hotspots in the past three years,which will be the main development directions in the future.Clusters such as hypertension,preventive treatment,and health management were identified,representing the main research themes at present.VOSviewer and CiteSpace were used for co-occurrence and clustering analysis of authors,revealing collaborative research networks,with prominent groups represented by WANG Qi,WANG Ji,LI Lingru,HOU Shujuan,ZHU Yanbo,etc.Conclusion:Research related to TCM constitution identification is developing rapidly,involving various aspects of medical care and daily life.However,there is still a need to build an extensive academic platform,strengthen the dissemination of Chinese medicine culture,standardize,intellectualize and universalize the identification of TCM constitution assessments,and construct a health service system with Chinese characteristics.
基金Research topics in key areas of Tianjin Administration of Traditional Chinese Medicine:"Establishment of quantitative model of Chinese medicine syndrome of swallowing dysfunction after stroke based on multi-dimensional item response theory and acupuncture intervention"(2023003)Hospital funded project of Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital:"To investigate the mechanism of acupuncture regulating endometrial receptivity from IL-10/HOXA10 axis"(2022002).
文摘Objective:The purpose of this study is to use CiteSpace software to examine the development patterns and hotspots in post-stroke hemiplegia research during the last 20 years.Methods:Articles about post-stroke hemiplegia from January 2005 to December 2024 were analyzed in the Web of Science database.CiteSpace software was used to conduct co-citation analysis of the articles about post-stroke hemiplegia as well as cooperative network analyses of authors,countries,and institutions,as well as keyword co-occurrence,clustering,emergence,and time line analyses.The results were displayed in a visual atlas.Result:A total of 2625 papers were obtained,and there were more publications overall.China and the United States had the most number of articles,while Chae,John was the author with the most number of articles.Capital Med University and Ohio State University had the most articles among their agencies.The keywords"stroke"and"rehabilitation"were used the most.The key word analysis indicates that the present study focus is on exercise rehabilitation measures and post-stroke treatment.Conclusion:Using CiteSpace software to analyze the literature on post-stroke hemiplegia,it is discovered that the use of new technologies in the field of mechanical thrombectomy and the effectiveness of rehabilitation techniques like mirror treatment are the key areas of study attention.This study has positive significance for finding safer and more effective treatments for post-stroke hemiplegia.
基金This study was supported by the Natural Science Foundation of Jilin Province of China,No.20200201495JCJilin Province Health Technology Innovation Project,No.2017J089。
文摘Stem cells have been confirmed to be involved in the occurrence and development of diabetic retinopathy;however,the underlying mechanisms remain unclear.In this study,we used Citespace software to visually analyze 552 articles exploring the stem cell-based treatment of diabetic retinopathy over the past 20 years,which were included in the Web of Science Core Collection.We found the following:(1)a co-citation analysis of the references cited by all 552 articles indicated 15 clusters.In cluster#0,representing the stem cell field,some highly cited landmark studies emerged between 2009–2013.For example,endothelial progenitor cells and diabetic retinopathy gradually received the full attention of scholars,in terms of their relationship and therapeutic prospects.Some researchers also verified the potential of adipose-derived stem cells to differentiate into stable retinal perivascular cells,using a variety of animal models of retinal vascular disease.All of these achievements provided references for the subsequent stem cell research.(2)An analysis of popular keywords among the 552 articles revealed that,during the past 20 years,a relative increase in basic research articles examining stem cells and endothelial progenitor cells for the treatment of diabetic retinopathy was observed.The contents of these articles primarily involved the expression of vascular endothelial growth factor,vascular regeneration,oxidative stress,and inflammatory response.(3)A burst analysis of keywords used in the 552 articles indicated that genetic and cytological research regarding the promotion of angiogenesis was an issue of concern from 2001 to 2012,including several studies addressing the expression of various growth factor genes;from 2014 to 2020,mouse models of diabetic retinopathy were recognized as mature animal models,and the most recent research has focused on macular degeneration,macular edema,neurodegeneration,and inflammatory changes in diabetic animal models.(4)Globally,the current authoritative studies have focused on basic research towards the stem cell treatment of diabetic retinopathy.Existing clinical studies are of low quality and have insufficient evidence levels,and their findings have not yet been widely accepted in clinical practice.Major challenges during stem cell transplantation remain,including stem cell heterogeneity,cell delivery,and the effective homing of stem cells to damaged tissue.However,clinical trials examining potential stem cell-based treatments of diabetic retinopathy,including the use of pluripotent stem cells,retinal pigment epithelial cells,bone marrow mesenchymal stem cells,and endothelial progenitor cells,are currently ongoing,and high-quality clinical evidence is likely to appear in the future,to promote clinical transformation.
基金supported by the Research Project on Medical Education launched by the Medical Education Branch of the Chinese Medical Association and the Medical Education Professional Committee of the Chinese Society of Higher Education in 2018(2018B-N18075)the Education Science Research Project of Beijing University of Chinese Medicine(XJYB2029)the Fundamental Research Funds for the Central Universities(2020-JYB-ZDGG-082).
文摘Objective:The objective of this study is to explore the current situation,clinical research hot spots,and trends of traditional Chinese medicine(TCM)nursing technology in rheumatoid arthritis(RA),to draw a panorama of clinical research,to provide the basis and clues for subsequent high-level evidence integration and further in-depth research.Materials and Methods:Seven databases including China National Knowledge Infrastructure,Chinese Scientific Journal Database(VIP),Wanfang Database,Chinese Biomedical Literature Database(Sino-Med),PubMed,Embase,and the Cochrane Library were searched.The bibliometric method and visualization software CiteSpace were used to conduct a multi-dimensional analysis of the included literature.Results:A total of 805 pieces of literature were included(of them,one was written in German and four in English),and the number of published literature showed an increasing trend year by year.There were only 30(3.73%)pieces of literature published in nursing journals.The hot spots of the co-occurrence map were concentrated in:(1)the nursing of fumigation in RA;(2)the efficacy evaluation of TCM nursing technology on pain,joint malformation,and joint dysfunction caused by RA.The included literature themes focused on five TCM technologies:fumigation,moxibustion,acupoint patching,acupoint injection,and Chinese herbal soaking.The beginning year and strength in TCM fumigation were 2012 and 5.2,and those in moxibustion were 2011 and 3.38.Conclusion:The related studies are on the rise.It has entered the field of international readers with clear research hot spots.However,there are still shortcomings such as little literature published in Chinese nursing core journals,few non-Chinese-related documents,and a lack of international exchanges and cooperation.The current research hot spots in this field are TCM fumigation,and the cutting-edge trend of future research may be fumigation and moxibustion technology.It is suggested that further research can focus on evidence integration and original research on the self-optimization of these two techniques.
基金Supported by National Natural Science Foundation of China(71774049)。
文摘[Objectives]Based on the related literature of benefit finding in China National Knowledge Infrastructure(CNKI),this paper analyzes the research status,hot spots and trends in this field.[Methods]To search for the related literature on benefit finding in China National Knowledge Infrastructure(CNKI),and use Citespace software to visually analyze the number of papers,authors,institutions and keywords.[Results]A total of 204 related papers were obtained,and the annual number of published papers showed a gradual increasing trend.The authors of published papers were represented by Zhang Fenglan,Liu Zhunzhun and Zhang Ting,and the Nursing College of Anhui Medical University published the most papers.The research focus was on social support,coping method and other influencing factors,and qualitative research was the main research type.The key population was breast cancer,stroke patients and their caregivers,and the development trend focused on reliability and validity test and correlation analysis.[Conclusions]The field of benefit finding in China is in the initial exploration stage,and there is little cooperation and exchange between authors and institutions.In the future,academic exchanges and multidisciplinary assistance should be strengthened to promote the rapid development of this field.
基金Jiangxi Traditional Chinese Medicine Administration Clinical Research Base Construction Project(Jiangxi TCM Science and Education Letter[2021]No.3)Jiangxi Traditional Chinese Medicine Young and Middle-aged Backbone Talents(First Batch)Training Program Project(Jiangxi TCM Science and Education Letter[2020]No.2)Jiangxi Traditional Chinese Medicine Administration Science and Technology Program Project(2021B050).
文摘Objective Through bibliometrics and visual analysis of the related studies on traditional Chinese medicine(TCM)treatment of immune thrombocytopenia(ITP),this study aims to sort out the overall research progress,hotspots,and trends in this field,and provide reference for further research in ITP.Methods The articles on ITP treated by TCM were retrieved from China National Knowledge Infrastructure(CNKI),Wanfang Database,China Science and Technology Journal Database(VIP),Web of Science Core Collection(WOSCC),and PubMed.The retrieval time was from the establishment of the databases to July 31,2022.VOSviewer,CiteSpace,Carrot2,and Note-Express were used for data analysis of the articles in terms of their quantities,types,and journals,and for visualization of research hotspots,authors,institutions,and keywords.Results 1493 Chinese articles and 40 English articles were included.The articles in Chinese mainly focus on clinical trial research and clinical experience summary,while the English articles mainly focus on clinical trial research and animal research.The Chinese articles were published in 317 Chinese journals,while English articles were published in 29 English journals.Research hotspots include the clinical syndrome differentiation of ITP,the therapeutic effect of TCM compounds on ITP,and the mechanism of ITP treatment.Keyword analysis shows that there are many research achievements in integrated traditional Chinese and western medicine treatment,clinical research,famous doctors’experience,TCM treatment,cellular immunity,and humoral immunity.The authors with the most articles in Chinese and English are Professor CHEN Xinyi and Professor MA Rou,respectively,and the research institutions with the most articles are Dongzhimen Hospital of Beijing University of Chinese Medicine and Xiyuan Hospital of China Academy of Chinese Medical Sciences.Chinese herbs often used to treat ITP clinically include Xianhecao(Agrimoniae Herba),Nvzhenzi(Ligustri Lucidi Fructus),Mohanlian(Ecliptae Herba),Zhongjiefeng(Sarcandrae Herba),etc.,and the prescription usually used to treat ITP include Guipi Decoction(归脾汤),Xijiao Dihuang Decoction(犀角地黄汤),Bazhen Decoction(八珍汤),Erzhi Pill(二至丸),and Xiaochaihu De-coction(小柴胡汤).The main development trends toward retrospective study,TCM treatment mechanism,and data mining.
基金Supported by the Science Fund for Creative Research Groups of National Natural Science Foundation of China(No.51021004)Tianjin Research Program of Application Foundation and Advanced Technology(No.12JCZDJC29200)National Key Technology R and D Program in the 12th Five-Year Plan of China(No.2011BAB10B06)
文摘It is difficult to analyze the inter-relationship for the construction layout of a reservoir project scientifically and intuitively.According to the characteristics of broad field and huge information,the modeling methods of digital terrain and solid model as well as the techniques of texture mapping and scene navigation are adopted.The simulation system is developed by C program language,which includes the functions of the interactive navigation of 3D scene,the visual inquiry of project digital model information,the storage and management of project information.A certain reservoir is taken as a case.The 3D visual analysis for the construction layout and engineering information are obtained.The proposed system is of great advantages in dealing with large amount of information and the method provides a theoretical basis and technical support for the construction layout of a reservoir project.
基金Supported by SJTU-HUAWEI TECH Cybersecurity Innovation Lab。
文摘Background With the development of information technology,there is a significant increase in the number of network traffic logs mixed with various types of cyberattacks.Traditional intrusion detection systems(IDSs)are limited in detecting new inconstant patterns and identifying malicious traffic traces in real time.Therefore,there is an urgent need to implement more effective intrusion detection technologies to protect computer security.Methods In this study,we designed a hybrid IDS by combining our incremental learning model(KANSOINN)and active learning to learn new log patterns and detect various network anomalies in real time.Conclusions Experimental results on the NSLKDD dataset showed that KAN-SOINN can be continuously improved and effectively detect malicious logs.Meanwhile,comparative experiments proved that using a hybrid query strategy in active learning can improve the model learning efficiency.
基金In-hospital Training Project of National Natural Science Foundation of China(04.03.19.153).
文摘[Objectives]To analyze the current research situation,hotspots and trends of curcumin and diabetes in recent 10 years.[Methods]Web of Science database was set as data source,the annual number of papers,the distribution of authors,the distribution of country/institution,the distribution of journals,the distribution of key words in the literature about curcumin and diabetes from January 1,2010 to March 31,2021 were quantitatively and visually analyzed with the aid of visualization software Bibliometrix.[Results]A total of 475 articles were included,and the annual number of papers was on the rise;the top three high-yielding countries were China(120 papers),India(65 papers),and the United States(58 papers).In terms of international cooperation,China and the United States had the most cooperation(27 papers);the top three high-yielding institutions were Wenzhou Medical University(42 papers),Mashhad University of Medical Sciences(41 papers)and Tehran University of Medical Sciences(30 papers);the most frequently cited authors were Wang Y(19 times),Li X(13 times),Li Y(12 times),Liang G(12 times)and Zhang Y(12 times);the top three journals in number of papers were Diabetology&Metabolic Syndrome(8 papers),PLoS One(8 papers),and European Journal of Pharmacology(7 papers),and the h index was 7,8,and 6,respectively;the most frequently cited journals were Diabetes(496 times),Journal of Biological Chemistry(486 times),PLoS One(347 times),Diabetes Care(284 times),and European Journal of Pharmacology(229 times);the most frequent key words mainly included oxidative stress,curcumin,insulin-resistance and expression;the hotspots were insulin resistance and NF-κB,mainly focusing on in vitro experiments.[Conclusions]The curcumin has good therapeutic potential in improving insulin resistance,inhibiting inflammation and oxidative stress,etc.The results are expected provide a reference and basis for scientific researchers to understand the current situation of curcumin and diabetes research and carry out the further research.
