Unequal virtual water transfer may aggravate local water scarcity risk.However,the quantitative confirmation of a clear geographic convergence between virtual water transfer and water scarcity risk remains undetermine...Unequal virtual water transfer may aggravate local water scarcity risk.However,the quantitative confirmation of a clear geographic convergence between virtual water transfer and water scarcity risk remains undetermined.We present an analytical framework that reveals the spatial matching between global water scarcity risk and virtual water trade inequality.This framework integrates a three-dimensional water scarcity risk assessment,hybrid input-output analysis,pollution trade term construction,and geographic convergence identification.The framework is applied to 123 countries for long-term validation from 1991 to 2021.We show that despite global improvements in water efficiency and security,countries exceeding the maximum water vulnerability threshold have increased by 50%.South Asia is the largest net exporter of virtual water.Central Asia exhibits the most pronounced virtual water trade inequality.To achieve the same economic growth,Central Asia needs to pay several times the local water consumption costs of developed regions(15.9−83.6 times,2021).In the past 30 years,the average geographic convergence index exceeded 0.8.Countries facing severe water scarcity also exhibit pronounced inequalities in virtual water trade,indicating that a significant geographic convergence relationship exists.Effectively responding to this unsustainable relationship necessitates balancing both domestic resource risk management and global virtual water trade regulation.展开更多
This paper sums up four security factors after analyzing co-residency threats caused by the special multitenant environment in the cloud.To secure the factors,a multiway dynamic trust chain transfer model was proposed...This paper sums up four security factors after analyzing co-residency threats caused by the special multitenant environment in the cloud.To secure the factors,a multiway dynamic trust chain transfer model was proposed on the basis of a measurement interactive virtual machine and current behavior to protect the integrity of the system.A trust chain construction module is designed in a virtual machine monitor.Through dynamic monitoring,it achieves the purpose of transferring integrity between virtual machine.A cloud system with a trust authentication function is implemented on the basis of the model,and its practicability is shown.展开更多
Cholesteryl ester transfer protein （CETP） is a plasma glycoprotein that plays an important role in decreasing high-density lipoprotein cholesterol （HDL-C） levels and increasing low-density lipoprotein cholesterol ...Cholesteryl ester transfer protein （CETP） is a plasma glycoprotein that plays an important role in decreasing high-density lipoprotein cholesterol （HDL-C） levels and increasing low-density lipoprotein cholesterol （LDL-C） levels. Inhibition of CETP may be a new therapy for treating atherosclerosis. Herein, we report the development of a ligand-based pharmacophore model and pharmacophore-based virtual screening of the ZINC/big-n-greasy database, leading to the identification of compound H-10 as a potential CETP inhibitor in vitro. Based on H-10, a series of 3-（（3,4-dichlorophenyl）（4-substituted benzyl）amino） propanamides were designed, synthesized, and evaluated against CETP. Compound 41 was found to have the best activity, resulting in 85.0% inhibition of CETP at l0 μmol/L.展开更多
This project was designated as Meritorious of Mathematical Contest inModeling (MCM'94). We have been required tu solve a problem of findins thebest schedule of a file transfer network in order to niake the niaktis...This project was designated as Meritorious of Mathematical Contest inModeling (MCM'94). We have been required tu solve a problem of findins thebest schedule of a file transfer network in order to niake the niaktispan the smallestone. Three situations with展开更多
虚拟货币因其去中心化、匿名性、跨境流动性等特性,成为犯罪分子转移涉案资金的新型媒介。目前主要存在“冷钱包F to F”“热钱包交易所撮合”“热钱包链上直转”三种涉案资金转移模式。以虚拟货币为资金转移媒介的作案方式,给侦查工作...虚拟货币因其去中心化、匿名性、跨境流动性等特性,成为犯罪分子转移涉案资金的新型媒介。目前主要存在“冷钱包F to F”“热钱包交易所撮合”“热钱包链上直转”三种涉案资金转移模式。以虚拟货币为资金转移媒介的作案方式,给侦查工作带来了身份信息获取难、资金链路分析难、资产查扣认定难、跨境数据调取难等实战痛点。公安机关应构建“五位一体”侦控模式,通过建立全链条打击体系、整合多维信息数据、深化区块链追踪技术应用、明确涉案资金鉴定标准、细化取证法律规定等措施,全面提升对利用虚拟货币转移涉案资金案件的打击效能。展开更多
基金supported by National Natural Science Foundation of China(Grant No.52279027)National Key R&D Program of China(Grant No.2021YFC3200201)+1 种基金Key Research Project on Decision Consultation of the Strategic Development Department of China Association for Science and Technology(Grant No.2023070615CG111504)China Engineering Science and Technology Development Strategy Henan Research Institute Strategic Consulting Research Project(Grant No.2024HENYB01).
文摘Unequal virtual water transfer may aggravate local water scarcity risk.However,the quantitative confirmation of a clear geographic convergence between virtual water transfer and water scarcity risk remains undetermined.We present an analytical framework that reveals the spatial matching between global water scarcity risk and virtual water trade inequality.This framework integrates a three-dimensional water scarcity risk assessment,hybrid input-output analysis,pollution trade term construction,and geographic convergence identification.The framework is applied to 123 countries for long-term validation from 1991 to 2021.We show that despite global improvements in water efficiency and security,countries exceeding the maximum water vulnerability threshold have increased by 50%.South Asia is the largest net exporter of virtual water.Central Asia exhibits the most pronounced virtual water trade inequality.To achieve the same economic growth,Central Asia needs to pay several times the local water consumption costs of developed regions(15.9−83.6 times,2021).In the past 30 years,the average geographic convergence index exceeded 0.8.Countries facing severe water scarcity also exhibit pronounced inequalities in virtual water trade,indicating that a significant geographic convergence relationship exists.Effectively responding to this unsustainable relationship necessitates balancing both domestic resource risk management and global virtual water trade regulation.
基金supported by The National Natural Science Foundation for Young Scientists of China under Grant No.61303263the Jiangsu Provincial Research Foundation for Basic Research(Natural Science Foundation)under Grant No.BK20150201+4 种基金the Scientific Research Key Project of Beijing Municipal Commission of Education under Grant No.KZ201210015015Project Supported by the National Natural Science Foundation of China(Grant No.61370140)the Scientific Research Common Program of the Beijing Municipal Commission of Education(Grant No.KMKM201410015006)The National Science Foundation of China under Grant Nos.61232016 and U1405254and the PAPD fund
文摘This paper sums up four security factors after analyzing co-residency threats caused by the special multitenant environment in the cloud.To secure the factors,a multiway dynamic trust chain transfer model was proposed on the basis of a measurement interactive virtual machine and current behavior to protect the integrity of the system.A trust chain construction module is designed in a virtual machine monitor.Through dynamic monitoring,it achieves the purpose of transferring integrity between virtual machine.A cloud system with a trust authentication function is implemented on the basis of the model,and its practicability is shown.
文摘Cholesteryl ester transfer protein （CETP） is a plasma glycoprotein that plays an important role in decreasing high-density lipoprotein cholesterol （HDL-C） levels and increasing low-density lipoprotein cholesterol （LDL-C） levels. Inhibition of CETP may be a new therapy for treating atherosclerosis. Herein, we report the development of a ligand-based pharmacophore model and pharmacophore-based virtual screening of the ZINC/big-n-greasy database, leading to the identification of compound H-10 as a potential CETP inhibitor in vitro. Based on H-10, a series of 3-（（3,4-dichlorophenyl）（4-substituted benzyl）amino） propanamides were designed, synthesized, and evaluated against CETP. Compound 41 was found to have the best activity, resulting in 85.0% inhibition of CETP at l0 μmol/L.
文摘This project was designated as Meritorious of Mathematical Contest inModeling (MCM'94). We have been required tu solve a problem of findins thebest schedule of a file transfer network in order to niake the niaktispan the smallestone. Three situations with
文摘虚拟货币因其去中心化、匿名性、跨境流动性等特性,成为犯罪分子转移涉案资金的新型媒介。目前主要存在“冷钱包F to F”“热钱包交易所撮合”“热钱包链上直转”三种涉案资金转移模式。以虚拟货币为资金转移媒介的作案方式,给侦查工作带来了身份信息获取难、资金链路分析难、资产查扣认定难、跨境数据调取难等实战痛点。公安机关应构建“五位一体”侦控模式,通过建立全链条打击体系、整合多维信息数据、深化区块链追踪技术应用、明确涉案资金鉴定标准、细化取证法律规定等措施,全面提升对利用虚拟货币转移涉案资金案件的打击效能。
