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Can preoperative planning using IRIS™three-dimensional anatomical virtual models predict operative findings during robot-assisted partial nephrectomy?
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作者 Ahmed Ghazi Nitin Sharma +6 位作者 Ahmed Radwan Hani Rashid Thomas Osinski Thomas Frye William Tabayoyong Jonathan Bloom Jean Joseph 《Asian Journal of Urology》 CSCD 2023年第4期431-439,共9页
Objective To evaluate the predictive validity of IRIS™(Intuitive Surgical®,Sunnyvale,CA,USA)as a planning tool for robot-assisted partial nephrectomy(RAPN)by assessing the degree of overlap with intraoperative ex... Objective To evaluate the predictive validity of IRIS™(Intuitive Surgical®,Sunnyvale,CA,USA)as a planning tool for robot-assisted partial nephrectomy(RAPN)by assessing the degree of overlap with intraoperative execution.Methods Thirty-one patients scheduled for RAPN by four experienced urologists were enrolled in a prospective study.Prior to surgery,urologists reviewed the IRIS™three-dimensional model on an iphone Operating System(iOS)app and completed a questionnaire outlining their surgical plan including surgical approach,and ischemia technique as well as confidence in executing this plan.Postoperatively,questionnaires assessing the procedural approach,clinical utility,efficiency,and effectiveness of IRIS™were completed.The degree of overlap between the preoperative and intraoperative questionnaires and between the planned approach and actual execution of the procedure was analyzed.Questionnaires were answered on a 5-point Likert scale and scores of 4 or greater were considered positive.Results Mean age was 65.1 years with a mean tumor size of 27.7 mm(interquartile range 17.5-44.0 mm).Hilar tumors consisted of 32.3%;48.4%of patients had R.E.N.A.L.nephrometry scores of 7-9.On preoperative questionnaires,the surgeons reported that in 67.7%cases they were confident that they can perform the procedure successfully,and on intraoperative questionnaires,the surgeons reported that in 96.8%cases IRIS™helped achieve good spatial sensation of the anatomy.There was a high degree of overlap between preoperative and intraoperative questionnaires for the surgical approach,interpreting anatomical details and clinical utility.When comparing plans for selective or off-clamp,the preoperative plan was executed in 90.0%of cases intraoperatively.Conclusion A high degree of overlap between the preoperative surgical approach and intraoperative RAPN execution was found using IRIS™.This is the first study to evaluate the predictive accuracy of IRIS™during RAPN by comparing preoperative plan and intraoperative execution. 展开更多
关键词 Renal cancer PATIENT-SPECIFIC Three-dimensional virtual model Imaging Partial nephrectomy Robotics
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Virtual modeling of robot-assisted manipulations in abdominal surgery
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作者 Stanislav V Berelavichus Grigory G Karmazanovsky +4 位作者 Vadim S Shirokov Valeriy A Kubyshkin Andrey G Kriger Evgeny V Kondratyev Olga P Zakharova 《World Journal of Gastrointestinal Surgery》 SCIE CAS 2012年第6期141-145,共5页
AIM:To determine the effectiveness of using multidetector computed tomography(MDCT)data in preoperative planning of robot-assisted surgery.METHODS:Fourteen patients indicated for surgery underwent MDCT using 64 and 25... AIM:To determine the effectiveness of using multidetector computed tomography(MDCT)data in preoperative planning of robot-assisted surgery.METHODS:Fourteen patients indicated for surgery underwent MDCT using 64 and 256-slice MDCT.Before the examination,a specially constructed navigation net was placed on the patient’s anterior abdominal wall.Processing of MDCT data was performed on a Brilliance Workspace 4(Philips).Virtual vectors that imitate robotic and assistant ports were placed on the anterior abdominal wall of the 3D model of the patient,considering the individual anatomy of the patient and the technical capabilities of robotic arms.Sites for location of the ports were directed by projection on the roentgen-positive tags of the navigation net.RESULTS:There were no complications observed during surgery or in the post-operative period.We were able to reduce robotic arm interference during surgery.The surgical area was optimal for robotic and assistant manipulators without any need for reinstallation of the trocars.CONCLUSION:This method allows modeling of the main steps in robot-assisted intervention,optimizing operation of the manipulator and lowering the risk of injuries to internal organs. 展开更多
关键词 virtual modeling Robotic SURGERY MULTIDETECTOR computed tomography ABDOMINAL SURGERY virtual SURGERY
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High Performance Analytics with SAP HANA Virtual Models
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作者 Abani Pattanayak 《Journal of Computer and Communications》 2017年第7期1-10,共10页
Informed decision-making, better communication and faster response to business situation are the key differences between leaders and followers in this competitive global marketplace. A data-driven organization can ana... Informed decision-making, better communication and faster response to business situation are the key differences between leaders and followers in this competitive global marketplace. A data-driven organization can analyze patterns & anomalies to make sense of the current situation and be ready for future opportunities. Organizations no longer have the problem of “lack of data”, but the problem of “actionable data” at the right time to act, direct and influence their business decisions. The data exists in different transactional systems and/or data warehouse systems, which takes significant time to retrieve/ process relevant information and negatively impacts the time window to out-maneuver the competition. To solve the problem of “actionable data”, enterprises can take advantage of the SAP HANA [1] in-memory platform that enables rapid processing and analysis of huge volumes of data in real-time. This paper discusses how SAP HANA virtual data models can be used for on-the-fly analysis of live transactional data to derive insight, perform what-if analysis and execute business transactions in real-time without using persisted aggregates. 展开更多
关键词 SAP HANA In-Memory COMPUTING virtual DATA model Advanced ANALYTICS BIG DATA
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Integrating geographic information system and 3D virtual reality for optimized modeling of large-scale photovoltaic wind hybrid system:A case study in Dakhla City,Morocco
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作者 Elmostafa Achbab Rachid Lambarki +1 位作者 Hassan Rhinane Dennoun Saifaoui 《Energy Geoscience》 2025年第2期174-193,共20页
This research pioneers the integration of geographic information systems(GIS)and 3D modeling within a virtual reality(VR)framework to assess the viability and planning of a 20 MW hybrid wind-solarphotovoltaic(PV)syste... This research pioneers the integration of geographic information systems(GIS)and 3D modeling within a virtual reality(VR)framework to assess the viability and planning of a 20 MW hybrid wind-solarphotovoltaic(PV)system connected to the local grid.The study focuses on Dakhla,Morocco,a region with vast untapped renewable energy potential.By leveraging GIS,we are innovatively analyzing geographical and environmental factors that influence optimal site selection and system design.The incorporation of VR technologies offers an unprecedented level of realism and immersion,allowing stakeholders to virtually experience the project's impact and design in a dynamic,interactive environment.This novel methodology includes extensive data collection,advanced modeling,and simulations,ensuring that the hybrid system is precisely tailored to the unique climatic and environmental conditions of Dakhla.Our analysis reveals that the region possesses a photovoltaic solar potential of approximately2400 k Wh/m^(2) per year,with an average annual wind power density of about 434 W/m^(2) at an 80-meter hub height.Productivity simulations indicate that the 20 MW hybrid system could generate approximately 60 GWh of energy per year and 1369 GWh over its 25-year lifespan.To validate these findings,we employed the System Advisor Model(SAM)software and the Global Solar Photovoltaic Atlas platform.This comprehensive and interdisciplinary approach not only provides a robust assessment of the system's feasibility but also offers valuable insights into its potential socio-economic and environmental impact. 展开更多
关键词 Geographic information systems 3D virtual reality(VR)modeling Wind energy Solar photovoltaic(PV)energy Hybrid renewable energy system assessment
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Research and Application of Caideng Model Rendering Technology for Virtual Reality
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作者 Xuefeng Wang Yadong Wu +1 位作者 Yan Luo Dan Luo 《Journal of Computer and Communications》 2024年第4期95-110,共16页
With the development of virtual reality (VR) technology, more and more industries are beginning to integrate with VR technology. In response to the problem of not being able to directly render the lighting effect of C... With the development of virtual reality (VR) technology, more and more industries are beginning to integrate with VR technology. In response to the problem of not being able to directly render the lighting effect of Caideng in digital Caideng scenes, this article analyzes the lighting model. It combines it with the lighting effect of Caideng scenes to design an optimized lighting model algorithm that fuses the bidirectional transmission distribution function (BTDF) model. This algorithm can efficiently render the lighting effect of Caideng models in a virtual environment. And using image optimization processing methods, the immersive experience effect on the VR is enhanced. Finally, a Caideng roaming interactive system was designed based on this method. The results show that the frame rate of the system is stable during operation, maintained above 60 fps, and has a good immersive experience. 展开更多
关键词 virtual Reality Caideng model Lighting model Point Light Rendering
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Virtual Reality-based Teleoperation with Robustness Against Modeling Errors 被引量:3
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作者 蒋再男 刘宏 +1 位作者 王捷 黄剑斌 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2009年第3期325-333,共9页
This article investigates virtual reality (VR)-based teleoperation with robustness against modeling errors. VR technology is an effective way to overcome the large time delay during space robot teleoperation. However,... This article investigates virtual reality (VR)-based teleoperation with robustness against modeling errors. VR technology is an effective way to overcome the large time delay during space robot teleoperation. However, it depends highly on the accuracy of model. Model errors between the virtual and real environment exist inevitably. The existing way to deal with the problem is by means of either model matching or robot compliance control. As distinct from the existing methods, this article tries to combine m... 展开更多
关键词 space robot TELEOPERATION virtual reality model error visual recognition compliance control
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Force-reflecting teleoperation of robots based on on-line correction of a virtual model 被引量:1
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作者 LIU Wei SONG Aiguo LI Huijun 《Frontiers of Electrical and Electronic Engineering in China》 CSCD 2007年第3期288-292,共5页
Virtual reality is an effective method to eliminate the influence of time delay.However,it depends on the precision of the virtual model.In this paper,we introduce a method that corrects the virtual model on-line to e... Virtual reality is an effective method to eliminate the influence of time delay.However,it depends on the precision of the virtual model.In this paper,we introduce a method that corrects the virtual model on-line to establish a more precise model.The geometric errors of the virtual model were corrected on-line by overlapping the graphics over the images and also by syncretizing the position and force information from the remote.Then the sliding average least squares(SALS)method was adopted to determine the mass,damp,and stiffness of the remote environment and use this information to amend the dynamic model of the environment.Experimental results demonstrate that the on-line correction method we proposed can effectively reduce the impact caused by time delay,and improve the operational performance of the teleoperation system. 展开更多
关键词 force-reflecting TELEOPERATION time delay virtual model on-line correction
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Differences in spatial understanding between physical and virtual models
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作者 Lei Sun Tomohiro Fukuda Toshiki Tokuhara Nobuyoshi Yabuki 《Frontiers of Architectural Research》 CSCD 2014年第1期28-35,共8页
In the digital age, physical models are still used as major tools in architectural and urban design processes. The reason why designers still use physical models remains unclear. In addition, physical and 3D virtual m... In the digital age, physical models are still used as major tools in architectural and urban design processes. The reason why designers still use physical models remains unclear. In addition, physical and 3D virtual models have yet to be differentiated. The answers to these questions are too complex to account for in all aspects. Thus, this study only focuses on the differences in spatial understanding between physical and virtual models. In particular, it emphasizes on the perception of scale. For our experiment, respondents were shown a physical model and a virtual model consecutively. A questionnaire was then used to ask the respondents to evaluate these models objectively and to establish which model was more accurate in conveying object size. Compared with the virtual model, the physical model tended to enable cluicker and more accurate comDarisons of building heights. 展开更多
关键词 Spatialunderstanding Scale perception Physical model virtual model virtual reality
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Towards reconstructing the Shakespeare’s first Globe Theatre: A virtual model for research and development
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作者 Paolo Croce Francesco Leccese +1 位作者 Mirko Mordagà Giacomo Salvadori 《Frontiers of Architectural Research》 CSCD 2022年第6期1104-1120,共17页
Shakespeare’s first Globe Theatre(early 17th century)is considered one of the most iconic theatres in English history,despite lasting less than twenty years and having little information directly attributable to its ... Shakespeare’s first Globe Theatre(early 17th century)is considered one of the most iconic theatres in English history,despite lasting less than twenty years and having little information directly attributable to its shape and size.This building,part of a wide variety of Elizabethan theatres found in London during a fertile period in the history of entertainment,has fascinated historians and scholars for years.Interest in Globe Theatre has led to several attempts at reconstruction around the world in recent decades,very few of which are historically reliable due to a lack of accurate sources and the need to adapt a historic building,burnt down in a fire in 1613,to modern safety standards.However,with the increasing evolution of modelling systems in a virtual environment,it is now possible to analyse the theatre in a spatially and historically more consistent way with surviving data.The aim of this paper is to provide a historically and constructively valid virtual model that can reopen the debate on the shapes and dimensions of Shakespeare’s first Globe Theatre.The model has been created by collecting the main hypotheses proposed by scholars.These were used to create the basic scheme,the plans,and then the whole theatre.Finally,the model was made available to encourage its use in future research and development. 展开更多
关键词 Globe Theatre Historical reconstruction virtual model Outdoor playhouses Vernacular architecture Timber-framed
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A new approach for time effect analysis of settlement for single pile based on virtual soil-pile model 被引量:9
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作者 吴文兵 王奎华 +1 位作者 张智卿 CHIN Jian Leo 《Journal of Central South University》 SCIE EI CAS 2012年第9期2656-2662,共7页
A new approach is proposed to analyze the settlement behavior for single pile embedded in layered soils. Firstly, soil layers surrounding pile shaft are simulated by using distributed Voigt model, and finite soil laye... A new approach is proposed to analyze the settlement behavior for single pile embedded in layered soils. Firstly, soil layers surrounding pile shaft are simulated by using distributed Voigt model, and finite soil layers under the pile end are assumed to be virtual soil-pile whose cross-section area is the same as that of the pile shaft. Then, by means of Laplace transform and impedance function transfer method to solve the static equilibrium equation of pile, the analytical solution of the displacement impedance fimction at the pile head is derived. Furthermore, the analytical solution of the settlement at the head of single pile is theoretically derived by virtue of convolution theorem. Based on these solutions, the influences of parameters of soil-pile system on the settlement behavior for single pile are analyzed. Also, comparison of the load-settlement response for two well-instrumented field tests in multilayered soils is given to demonstrate the effectiveness and accuracy of the proposed approach. It can be noted that the presented solution can be used to calculate the settlement of single pile for the preliminary design of pile foundation. 展开更多
关键词 SETTLEMENT time effect single pile virtual soil-pile model layered soil VISCOELASTICITY distributed Voigt model
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Simulation study of a magnetocardiogram based on a virtual heart model:effect of a cardiac equivalent source and a volume conductor 被引量:3
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作者 寿国法 夏灵 +2 位作者 马平 唐发宽 戴灵 《Chinese Physics B》 SCIE EI CAS CSCD 2011年第3期121-128,共8页
In this paper, we present a magnetocardiogram (MCG) simulation study using the boundary element method (BEM) and based on the virtual heart model and the realistic human volume conductor model. The different contr... In this paper, we present a magnetocardiogram (MCG) simulation study using the boundary element method (BEM) and based on the virtual heart model and the realistic human volume conductor model. The different contributions of cardiac equivalent source models and volume conductor models to the MCG are deeply and comprehensively investigated. The single dipole source model, the multiple dipoles source model and the equivalent double layer (EDL) source model are analysed and compared with the cardiac equivalent source models. Meanwhile, the effect of the volume conductor model on the MCG combined with these cardiac equivalent sources is investigated. The simulation results demonstrate that the cardiac electrophysiological information will be partly missed when only the single dipole source is taken, while the EDL source is a good option for MCG simulation and the effect of the volume conductor is smallest for the EDL source. Therefore, the EDL source is suitable for the study of MCG forward and inverse problems, and more attention should be paid to it in future MCG studies. 展开更多
关键词 virtual heart model MAGNETOCARDIOGRAM dipole source equivalent double layer source volume conductor model
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Science Letters:Dynamic concision for three-dimensional reconstruction of human organ built with virtual reality modelling language (VRML) 被引量:3
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作者 禹正杨 郑树森 +2 位作者 陈雷霆 何晓乾 王建军 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2005年第7期611-616,共6页
This research studies the process of 3D reconstruction and dynamic concision based on 2D medical digital images using virtual reality modelling language (VRML) and JavaScript language, with a focus on how to realize t... This research studies the process of 3D reconstruction and dynamic concision based on 2D medical digital images using virtual reality modelling language (VRML) and JavaScript language, with a focus on how to realize the dynamic concision of 3D medical model with script node and sensor node in VRML. The 3D reconstruction and concision of body internal organs can be built with such high quality that they are better than those obtained from the traditional methods. With the function of dynamic concision, the VRML browser can offer better windows for man-computer interaction in real-time environment than ever before. 3D reconstruction and dynamic concision with VRML can be used to meet the requirement for the medical observation of 3D reconstruction and have a promising prospect in the fields of medical imaging. 展开更多
关键词 virtual Reality modelling Language (VRML) Direct texture mapping Three-dimensional reconstruction Dynamic concision
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Impact time control guidance against maneuvering targets based on a nonlinear virtual relative model 被引量:2
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作者 Yuru BIN Hui WANG +2 位作者 Defu LIN Yaning WANG Xin SUN 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2023年第7期444-459,共16页
Aiming at the problem of high-precision interception of air-maneuvering targets with impact time constraints,this paper proposes a novel guidance law based on a nonlinear virtual relative model in which the origin is ... Aiming at the problem of high-precision interception of air-maneuvering targets with impact time constraints,this paper proposes a novel guidance law based on a nonlinear virtual relative model in which the origin is attached to the target.In this way,the original maneuvering target is transformed into a stationary one.A polynomial function of the guidance command in the range domain with two unknown coefficients is introduced into the virtual model,one of the coefficients is determined to achieve the impact time constraint,and the other is determined to satisfy a newly defined virtual look angle constraint.For meeting the terminal constraints simultaneously,the guidance command can finally be obtained.The resulting solution is represented as a combination of proportional navigation guidance-like term which is aimed to meet the zero miss distance constraint,a bias term for impact time control by adjusting the length of the homing trajectory,and an additional term for target maneuvers.Numerous simulations demonstrate that the proposed law achieves an acceptable impact time error for various initial conditions against different types of maneuvering targets and shows more effective performance in comparison with those of other existing guidance laws. 展开更多
关键词 Impact time control Maneuvering targets Polynomial guidance virtual relative model virtual look angle constraint
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A Critical Model Construction of Knowledge Sharing Mechanism in Virtual Organization Based on Game Theoretic Perspective 被引量:9
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作者 LU Jinrong 《Wuhan University Journal of Natural Sciences》 CAS CSCD 2015年第6期465-470,共6页
Virtual organization uses information technology to achieve a closer integration and better management of business relationships between internal and external parties. There are many emerging issues in virtual organiz... Virtual organization uses information technology to achieve a closer integration and better management of business relationships between internal and external parties. There are many emerging issues in virtual organization and one of them is knowl- edge sharing. Knowledge sharing that is the core of knowledge management plays a key role in virtual organization. However, game theoretic exploration about knowledge sharing mechanism based on virtual organization is seldom published, In this study, knowledge sharing mechanism in virtual organization enterprise is explored using game theories from two aspects based on the features of knowledge sharing in virtual organization enterprise. Fi- nally, the critical model of knowledge sharing mechanism in virtual organization also is presented based on the perspective of game analysis. 展开更多
关键词 game theoretic analysis knowledge sharing virtual organization critical model
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Top-level modeling theory of multi-discipline virtual prototype 被引量:2
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作者 Tingyu Lin Xudong Chai Bohu Li 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2012年第3期425-437,共13页
Multi-disciplinary virtual prototypes of complex products are increasingly and widely used in modern advanced manufactur- ing. How to effectively address the problems of unified modeling, composition and reuse based o... Multi-disciplinary virtual prototypes of complex products are increasingly and widely used in modern advanced manufactur- ing. How to effectively address the problems of unified modeling, composition and reuse based on the multi-disciplinary heteroge- neous models has brought great challenges to the modeling and simulation (M&S) science and technology. This paper presents a top-level modeling theory based on the meta modeling framework (M2F) of the COllaborative SIMulation (COSlM) theory of virtual prototyping to solve the problems. Firstly the fundamental prin- ciples of the top-level modeling theory are decribed to expound the premise, assumptions, basic conventions and special require- ments in the description of complex heterogeneous systems. Next the formalized definitions for each factor in top level modeling are proposed and the hierarchical nature of them is illustrated. After demonstrating that they are self-closing, this paper divides the top- level modeling into two views, static structural graph and dynamic behavioral graph. Finally, a case study is discussed to demon- strate the feasibility of the theory. 展开更多
关键词 top-level modeling virtual prototype complex product multi-discipline modeling and simulation.
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Characterization for elastic constants of fused deposition modelling-fabricated materials based on the virtual fields method and digital image correlation 被引量:4
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作者 Quankun Cao Huimin Xie 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2017年第6期1075-1083,共9页
Fused deposition modelling(FDM), a widely used rapid prototyping process, is a promising technique in manufacturing engineering. In this work, a method for characterizing elastic constants of FDM-fabricated materials ... Fused deposition modelling(FDM), a widely used rapid prototyping process, is a promising technique in manufacturing engineering. In this work, a method for characterizing elastic constants of FDM-fabricated materials is proposed. First of all, according to the manufacturing process of FDM, orthotropic constitutive model is used to describe the mechanical behavior. Then the virtual fields method(VFM) is applied to characterize all the mechanical parameters(Q, Q, Q, Q) using the full-field strain,which is measured by digital image correlation(DIC). Since the principal axis of the FDM-fabricated structure is sometimes unknown due to the complexity of the manufacturing process, a disk in diametrical compression is used as the load configuration so that the loading angle can be changed conveniently. To verify the feasibility of the proposed method, finite element method(FEM) simulation is conducted to obtain the strain field of the disk. The simulation results show that higher accuracy can be achieved when the loading angle is close to 30?. Finally, a disk fabricated by FDM was used for the experiment. By rotating the disk, several tests with different loading angles were conducted. To determine the position of the principal axis in each test, two groups of parameters(Q, Q, Q, Q) are calculated by two different groups of virtual fields. Then the corresponding loading angle can be determined by minimizing the deviation between two groups of the parameters. After that, the four constants(Q, Q, Q, Q) were determined from the test with an angle of 27?. 展开更多
关键词 Fused deposition modelling virtual fields method Digital image correlation Orthotropic constitutive model Disk compression
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Virtual population pharmacokinetic using physiologically based pharmacokinetic model for evaluating bioequivalence of oral lacidipine formulations in dogs 被引量:5
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作者 Bin Yang Chunnuan Wu +4 位作者 Bin Ji Mingrui Wu Zhonggui He Lei Shang Jin Sun 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS 2017年第1期98-104,共7页
The aim of the present study was to investigate virtual population pharmacokinetic using physiologically based pharmacokinetic(PBPK) model for evaluating bioequivalence of oral lacidipine formulations in dogs. The dis... The aim of the present study was to investigate virtual population pharmacokinetic using physiologically based pharmacokinetic(PBPK) model for evaluating bioequivalence of oral lacidipine formulations in dogs. The dissolution behaviors of three lacidipine formulations including one commercial product and two self-made amorphous solid dispersions(ASDs)capsules were determined in 0.07% Tween 80 media. A randomized 3-period crossover design in 6 healthy beagle dogs after oral administration of the three formulations at a single dose of 4 mg was conducted. The PBPK modeling was utilized for the virtual bioequivalence study.In vitro dissolution experiment showed that the dissolution behaviors of lacidipine amorphous solid dispersions(ASDs) capsules, which was respectively prepared by HPMC-E5 or Soluplus, as polymer displayed similar curves compared with the reference formulation in 0.07% Tween 80 media. In vivo pharmacokinetics experiments showed that three formulations had comparable maximum plasma drug concentration(Cmax), and the time(Tmax) to reach Cmax of lacidipine tablet, which was prepared by Soluplus, as polymer was slower than other two formulations in consistency with the in vitro dissolution rate. The 90% confidence interval(CI) for the Cmax, AUC0–24 h and AUC0–∞ of the ratio of the test drug to the reference drug exceeded the acceptable bioequivalence(BE) limits(0.80–1.25). However, the 90% CI of the AUC0–24 h, AUC0–∞ and Cmax of the ratio of test to reference drug were within the BE limit,calculated using PBPK modeling when the virtual subjects reached 24 dogs. The results all demonstrated that virtual bioequivalence study can overcome the inequivalence caused by inter-subject variability of the 6 beagle dogs involved in in vivo experiments. 展开更多
关键词 Physiologically based PHARMACOKINETIC model virtual POPULATION PHARMACOKINETIC BIOEQUIVALENCE LACIDIPINE Amorphous solid DISPERSIONS
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Evaluation Model of Design for Operation and Architecture of Hierarchical Virtual Simulation for Flight Vehicle Design 被引量:6
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作者 LIU Hua TIAN Yongliang +2 位作者 ZHANG Chaoying YIN Jiao SUN Yijie 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2012年第2期216-226,共11页
In order to take requirements for commercial operations or military missions into better consideration in new flight vehicle design, a tri-hierarchical task classification model of "design for operation" is proposed... In order to take requirements for commercial operations or military missions into better consideration in new flight vehicle design, a tri-hierarchical task classification model of "design for operation" is proposed, which takes basic man-object interaction task, complex collaborative operation and large-scale joint operation into account. The corresponding general architecture of evaluation criteria is also depicted. Then a virtual simulation-based approach to implement the evaluations at three hierarchy levels is mainly analyzed with a detailed example, which validates the feasibility and effectiveness of evaluation architecture. Finally, extending the virtual simulation architecture from design to operation training is discussed. 展开更多
关键词 flight vehicle design operation virtual simulation TRAINING evaluation model
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Universal Mechanism Modeling Method in Virtual Assembly Environment 被引量:2
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作者 LIU Jianhua ZHANG Zhixian LIU Yang 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2012年第6期1105-1114,共10页
Motion simulation and performance analysis of mechanism are important methods for analyzing assembly quality after finishing assembly simulation in virtual assembly environment. However, most simulation systems have n... Motion simulation and performance analysis of mechanism are important methods for analyzing assembly quality after finishing assembly simulation in virtual assembly environment. However, most simulation systems have no function of mechanism motion simulation due to the randomicity of mechanism and lack of universal mechanism modeling method. In order to realize the simulation of any mechanism after finishing assembly simulation in a virtual environment, a new universal mechanism modeling method is presented. Two main models are contained in the mechanism model: information model and mathematical model. Firstly, the information model of mechanism is proposed to describe the data structure of mechanism which contains bottom geometry data, information of constraint, link, kinematic pair and physical data. Because the object of mechanism simulation is the assembly, which is assembled during the process of assembly simulation, the information of mechanism can be obtained automatically through mechanism automatic search method. Secondly, mathematical model of mechanism is presented. The mathematical model uses mathematical method to express the mechanism. In order to realize the automatic expression of any random mechanism, basic constraint library is presented, consequently random mechanism can be described based on the basic constraint library. Finally, two examples are introduced to validate the method in the prototype system named VAPP(Virtual Assembly Process Planning). The validation result shows that the mechanism modeling provides a universal modeling method for mechanism motion simulation in virtual assembly environment. This research has important effect on the development both of mechanism motion simulation and virtual assembly. 展开更多
关键词 virtual assembly mechanism modeling motion simulation constraint library information model mathematical model
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A MULTISCALE MECHANICAL MODEL FOR MATERIALS BASED ON VIRTUAL INTERNAL BOND THEORY 被引量:6
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作者 Zhang Zhennan Ge Xiurun Li Yonghe 《Acta Mechanica Solida Sinica》 SCIE EI 2006年第3期196-202,共7页
Only two macroscopic parameters are needed to describe the mechanical properties of linear elastic solids, i.e. the Poisson's ratio and Young's modulus. Correspondingly, there should be two microscopic parameters to... Only two macroscopic parameters are needed to describe the mechanical properties of linear elastic solids, i.e. the Poisson's ratio and Young's modulus. Correspondingly, there should be two microscopic parameters to determine the mechanical properties of material if the macroscopic mechanical properties of linear elastic solids are derived from the microscopic level. Enlightened by this idea, a multiscale mechanical model for material, the virtual multi-dimensional internal bonds (VMIB) model, is proposed by incorporating a shear bond into the virtual internal bond (VIB) model. By this modification, the VMIB model associates the macro mechanical properties of material with the microscopic mechanical properties of discrete structure and the corresponding relationship between micro and macro parameters is derived. The tensor quality of the energy density function, which contains coordinate vector, is mathematically proved. From the point of view of VMIB, the macroscopic nonlinear behaviors of material could be attributed to the evolution of virtual bond distribution density induced by the imposed deformation. With this theoretical hypothesis, as an application example, a uniaxial compressive failure of brittle material is simulated. Good agreement between the experimental results and the simulated ones is found. 展开更多
关键词 virtual multi-dimensional internal bond material property dimensionality multiscale modeling molecular dynamics virtual internal bond
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