Background This study aimed to evaluate the relationship between vestibular and auditory functions in pediatric patients with sudden sensorineural hearing loss(SSHL).Methods A total of 30 pediatric patients experienci...Background This study aimed to evaluate the relationship between vestibular and auditory functions in pediatric patients with sudden sensorineural hearing loss(SSHL).Methods A total of 30 pediatric patients experiencing unilateral SSHL between 5.9 and 13.0 years of age were enrolled in this study.Pure tone audiometry was evaluated prior to treatment initiation and again after one month of treatment.Prior to treatment initiation,vertigo symptoms were noted;then several vestibular function tests were conducted including caloric testing,ocular vestibular evoked myogenic potentials(o-VEMPs)and cervical vestibular evoked myogenic potentials(c-VEMPs).Associations between pre and post-treatment vestibular function and hearing threshold levels were analyzed.Results Initial hearing thresholds of children with vertigo were higher than thresholds of children without vertigo(92 dB vs 79 dB,F=0.033),while initial hearing thresholds of children with abnormal caloric test findings were higher than thresholds of children with normal caloric test findings(93 dB vs 67 dB.P=0.014).Cutoff values of hearing thresholds for those with vertigo symptoms and abnormal vestibular test results were 86.000-and 89.583-dB HL.respectively.Regarding prognosis,children with vertigo exhibited lower recovery rates than children without vertigo(33%vs 75%,P=0.025);recovery rates of children with abnormal caloric test results were lower than the overall recovery rate(25%vs 73%,respectively,P=0.039).Conclusion Assessments of vertigo symptoms and vestibular function are useful tools in predicting pediatric SwSHL patient disease severity and prognosis.展开更多
Vestibular schwannomas(VS)are benign tumors of the vestibular nerve.The common first symptoms are hearing loss and tinnitus,followed by imbalance,vertigo,and facial nerve involvement.The subjective symptoms of VS pati...Vestibular schwannomas(VS)are benign tumors of the vestibular nerve.The common first symptoms are hearing loss and tinnitus,followed by imbalance,vertigo,and facial nerve involvement.The subjective symptoms of VS patients are not consistent with the severity of vestibular lesions and the results of vestibular tests,which often interfere with clinicians’diagnoses.Thus,the main screening and diagnostic methods for VS are audiometry and magnetic resonance imaging(MRI),ignoring the evaluation of vestibular function at the source of pathological lesions.With the development and improvement of vestibular evaluation technology and its wide application in the clinic,modern vestibular examination technology can reflect the severity and frequency of vestibular lesions and compensation from multiple perspectives,providing an objective basis for the diagnosis and treatment of vestibular diseases.In this report,we review the results and characteristics of vestibular tests in VS patients and further clarify the clinical value of vestibular function assessment in the diagnosis and treatment of VS.展开更多
Subjective visual vertical(SVV)and subjective visual horizontal(SVH)tests can be used to evaluate the perception of verticality and horizontality,respectively,and can aid the diagnosis of otolith dysfunction in clinic...Subjective visual vertical(SVV)and subjective visual horizontal(SVH)tests can be used to evaluate the perception of verticality and horizontality,respectively,and can aid the diagnosis of otolith dysfunction in clinical practice.In this study,SVV and SVH screen version tests are implemented using virtual reality(VR)equipment;the proposed test method promotes a more immersive feeling for the subject while using a simple equipment configuration and possessing excellent mobility.To verify the performance of the proposed VR-based SVV and SVH tests,a reliable comparison was made between the traditional screen-based SVV and SVH tests and the proposed method,based on 30 healthy subjects.The average results of our experimental tests on the VR-based binocular SVV and SVH equipment were−0.15◦±1.74 and 0.60◦±1.18,respectively.The proposed VR-based method satisfies the normal tolerance for horizontal or vertical lines,i.e.,a±3◦error,as defined in previous studies,and it can be used to replace existing test methods.展开更多
目的评价常染色体显性遗传性脑动脉病伴皮质下梗死和白质脑病(cerebral autosomald ominant arteriopathy with subcortical infarcts and leukoencephalopathy,CADASIL)的前庭功能状态。方法CADASIL患者和健康志愿者各17名,进行眼震电...目的评价常染色体显性遗传性脑动脉病伴皮质下梗死和白质脑病(cerebral autosomald ominant arteriopathy with subcortical infarcts and leukoencephalopathy,CADASIL)的前庭功能状态。方法CADASIL患者和健康志愿者各17名,进行眼震电图检查,包括凝视性眼震试验、自发性眼震试验、水平扫视试验、水平跟踪试验、水平视动性眼震试验和温度试验,比较两组间结果的差异。结果两组受试者均未发现自发性眼震和凝视性眼震。水平扫视试验中,两组间扫视潜伏期和扫视速度无统计学差异。CADASIL组扫视准确度均低于正常对照组,向左扫视时差异有统计学意义(F=5.751,P<0.05)。水平跟踪试验中,CADASIL组跟踪增益值(gain,G)(G左:0.79±0.08,G右:0.76±0.12)小于对照组(G左:0.87±0.04,G右:0.86±0.06),差异有统计学意义(t=-3.739、-2.911,均P<0.05)。按照跟踪曲线类型将CADASIL组分为跟踪正常亚组和跟踪异常亚组,发现头晕症状与跟踪运动异常有关(P<0.05)。水平视动性眼震试验发现CADASIL组视动性眼震增益值(G左:0.79±0.17,G右:0.78±0.18)小于对照组(G左:0.90±0.08,G右:0.89±0.09),差异有统计学意义(t=-2.342、-2.335,均P<0.05)。1例患者进行了温度试验,表现为固视抑制失败。结论CADASIL患者存在中枢前庭功能损害,并且与患者的头晕症状有关。展开更多
基金supported by the Special Fund of the Pediatric Medical Coordinated Development Center of Beijing Hospitals Authority,No.XTYB201828Beijing Hospitals Authority'Ascent Plan,No.DFL20191201.
文摘Background This study aimed to evaluate the relationship between vestibular and auditory functions in pediatric patients with sudden sensorineural hearing loss(SSHL).Methods A total of 30 pediatric patients experiencing unilateral SSHL between 5.9 and 13.0 years of age were enrolled in this study.Pure tone audiometry was evaluated prior to treatment initiation and again after one month of treatment.Prior to treatment initiation,vertigo symptoms were noted;then several vestibular function tests were conducted including caloric testing,ocular vestibular evoked myogenic potentials(o-VEMPs)and cervical vestibular evoked myogenic potentials(c-VEMPs).Associations between pre and post-treatment vestibular function and hearing threshold levels were analyzed.Results Initial hearing thresholds of children with vertigo were higher than thresholds of children without vertigo(92 dB vs 79 dB,F=0.033),while initial hearing thresholds of children with abnormal caloric test findings were higher than thresholds of children with normal caloric test findings(93 dB vs 67 dB.P=0.014).Cutoff values of hearing thresholds for those with vertigo symptoms and abnormal vestibular test results were 86.000-and 89.583-dB HL.respectively.Regarding prognosis,children with vertigo exhibited lower recovery rates than children without vertigo(33%vs 75%,P=0.025);recovery rates of children with abnormal caloric test results were lower than the overall recovery rate(25%vs 73%,respectively,P=0.039).Conclusion Assessments of vertigo symptoms and vestibular function are useful tools in predicting pediatric SwSHL patient disease severity and prognosis.
文摘Vestibular schwannomas(VS)are benign tumors of the vestibular nerve.The common first symptoms are hearing loss and tinnitus,followed by imbalance,vertigo,and facial nerve involvement.The subjective symptoms of VS patients are not consistent with the severity of vestibular lesions and the results of vestibular tests,which often interfere with clinicians’diagnoses.Thus,the main screening and diagnostic methods for VS are audiometry and magnetic resonance imaging(MRI),ignoring the evaluation of vestibular function at the source of pathological lesions.With the development and improvement of vestibular evaluation technology and its wide application in the clinic,modern vestibular examination technology can reflect the severity and frequency of vestibular lesions and compensation from multiple perspectives,providing an objective basis for the diagnosis and treatment of vestibular diseases.In this report,we review the results and characteristics of vestibular tests in VS patients and further clarify the clinical value of vestibular function assessment in the diagnosis and treatment of VS.
基金supported by the Soonchunhyang University Research Fund and 2018 Ulsan University Hospital Research Grant(UUH-2018-12)(Grantee:JYP,http://www.uuh.ulsan.kr).The authors are grateful for their supports.
文摘Subjective visual vertical(SVV)and subjective visual horizontal(SVH)tests can be used to evaluate the perception of verticality and horizontality,respectively,and can aid the diagnosis of otolith dysfunction in clinical practice.In this study,SVV and SVH screen version tests are implemented using virtual reality(VR)equipment;the proposed test method promotes a more immersive feeling for the subject while using a simple equipment configuration and possessing excellent mobility.To verify the performance of the proposed VR-based SVV and SVH tests,a reliable comparison was made between the traditional screen-based SVV and SVH tests and the proposed method,based on 30 healthy subjects.The average results of our experimental tests on the VR-based binocular SVV and SVH equipment were−0.15◦±1.74 and 0.60◦±1.18,respectively.The proposed VR-based method satisfies the normal tolerance for horizontal or vertical lines,i.e.,a±3◦error,as defined in previous studies,and it can be used to replace existing test methods.
文摘目的评价常染色体显性遗传性脑动脉病伴皮质下梗死和白质脑病(cerebral autosomald ominant arteriopathy with subcortical infarcts and leukoencephalopathy,CADASIL)的前庭功能状态。方法CADASIL患者和健康志愿者各17名,进行眼震电图检查,包括凝视性眼震试验、自发性眼震试验、水平扫视试验、水平跟踪试验、水平视动性眼震试验和温度试验,比较两组间结果的差异。结果两组受试者均未发现自发性眼震和凝视性眼震。水平扫视试验中,两组间扫视潜伏期和扫视速度无统计学差异。CADASIL组扫视准确度均低于正常对照组,向左扫视时差异有统计学意义(F=5.751,P<0.05)。水平跟踪试验中,CADASIL组跟踪增益值(gain,G)(G左:0.79±0.08,G右:0.76±0.12)小于对照组(G左:0.87±0.04,G右:0.86±0.06),差异有统计学意义(t=-3.739、-2.911,均P<0.05)。按照跟踪曲线类型将CADASIL组分为跟踪正常亚组和跟踪异常亚组,发现头晕症状与跟踪运动异常有关(P<0.05)。水平视动性眼震试验发现CADASIL组视动性眼震增益值(G左:0.79±0.17,G右:0.78±0.18)小于对照组(G左:0.90±0.08,G右:0.89±0.09),差异有统计学意义(t=-2.342、-2.335,均P<0.05)。1例患者进行了温度试验,表现为固视抑制失败。结论CADASIL患者存在中枢前庭功能损害,并且与患者的头晕症状有关。
