Objective To observe the effect of three vertigo-stopping needles on the contents of neuropeptide Y （NPY）, endothelin （ET） and calcitonin gene-related peptide （CGRP） in plasma of patients with cervical vertigo, ...Objective To observe the effect of three vertigo-stopping needles on the contents of neuropeptide Y （NPY）, endothelin （ET） and calcitonin gene-related peptide （CGRP） in plasma of patients with cervical vertigo, and to explore its mechanism of treatment. Methods One hundred and eighty patients with cervical vertigo were divided into group A [acupuncture at R6nyfng （人迎ST 9） and Fengchi （风池 GB 20）, and frontal line], group B [acupuncture at Jing jiaji （颈夹脊）, GB 20 and Baihui （百会 GV 20）] and group C [intravenous infusion with ligustrazine and oral administration with flunarizine] according to simple randomization, with 60 cases in each group. For the patients in group A and group B, the treatment was conducted once a day, and ten times were considered as one course of treatment. Two days were free of treatment between two courses, and two courses were needed. For the patients in group C, the treatment was conducted for fifteen days. The contents of NPY, ET and CGRP in plasma before and after treatment were detected in patients with cervical vertigo. Results The contents of NPY in plasma of patients in the three groups after treatment were markedly lower than that before treatment （all P〈0.01）, and the differences were not statistically significant when compared the descending degrees among three groups （P〉0.05）. The contents of ET in plasma of patients in the three groups after treatment were markedly lower than that before treatment （P〈0.05, P〈0.01）, the descending degree in group A was greater than that in group B and group C, and the difference was statistically significant （P〈0.O1, P〈O.05）; while the difference was not statistically significant when compared the descending degrees between group B and group C （P〉0.05）. The contents of CGRP in plasma of patients in the three groups after treatment were markedly higher than that before treatment （P〈0.05, P〈O.O1）, the increasing degree in group A was greater than that in group B and group C, and the difference was statistically significant （both P〈0.05）; while the difference was not statistically significant when compared the increasing degrees between group B and group C （P〉0.05）. Conclusion Three vertigo-stopping needles, acupuncture and medication can regulate the contents of NPY, ET and CGRP in plasma of patients with cervical vertigo, while three vertigo-stopping needles is significantly superior to acupuncture and medication in reducing ET and increasing CGRP.展开更多
Objective To explore the therapeutic efficacy and mechanism of acupuncture at Lieque （列缺 LU 7） in treatment of cervical vertigo （CV）. Methods Forty CV patients met the inclusion criteria were enrolled and treate...Objective To explore the therapeutic efficacy and mechanism of acupuncture at Lieque （列缺 LU 7） in treatment of cervical vertigo （CV）. Methods Forty CV patients met the inclusion criteria were enrolled and treated with acupuncture at bilateral LU 7 points, once daily with 10 times as a course. The changes of blood flow velocity in bilateral vertebral artery and basilar artery were observed through transcranial doppler sonography （TCD） before treatment, after deqi with acupuncture and after a course of treatment, respectively. The scores and therapeutic efficacy on clinical symptoms were assessed according to CV symptoms and the functional assessment scale as well as the Criteria-for Diagnosis and Curative Effect in TCM Syndromes before treatment and after a course of treatment. Results Before treatment, after deqi and after a course of treatment, the blood flow velocity of basilar artery （BA）, left vertebral artery （LVA） and right vertebral artery （RVA） in 22 patients with a decreased blood flow velocity were respectively 23.20±4.84 vs 26.30 ± 4.17 vs 29.20 ± 4.20 （mm/s, BA）, 21.65 ± 3.62 vs 24.20 ± 2.89 vs 26.40 ± 3.62 （mm/s, LVA） and 21.90±3.04 vs 24.25±3.01 vs 26.50_±3.95 （mm/s, RVA）, while in 18 patients with an increased blood flow velocity were respectively 39.94 ± 8.24 vs 35.17 ± 4.84 vs 32.06 ± 3.49 （mm/s, BA）, 41.83 ± 5.64 vs 37.28 ± 2.32 vs 35.61 ± 2.09 （mm/s, LVA） and 37.11 ± 9.83 vs 32.22 ± 6.13 vs 28.11 ± 4.12 （mm/s, RVA）. Except that the difference of blood flow velocity of RVA was not significant in patients with an increased blood flow velocity before treatment and after deqi （P 〉 0.05）, the Vm of all vessels in 40 patients was improved after deqi with acupuncture and a course of treatment （P〈0.01, P〈0.05）. According to CV symptoms and the functional assessment scale, before treatment and after a course of treatment, the scores were 15.68 ± 5.35 and 26.30 ± 3.76, respectively, indicating that after a course of treatment, the symptoms were significantly improved （P 〈 0.01）. According to the Criteria for Diagnosis and Curative E.f]ect in TCM Syndromes, after a course of treatment, the total effective rate was 100% （40/40） and the cured rate was 55.0% （22/40）. Conclusion Acupuncture at LU 7 not only improves the blood supply of vertebral-basilar artery in CV patients, but also has a significant curative effect on improving the clinical symptoms.展开更多
Objective： To investigate the relationship among plasma endothelin（ET）, calcitonin gene-related peptide（CGRP） and blood flow rate of bilateral vertebral arteries in patients with cervical vertigo（CV） and to ass...Objective： To investigate the relationship among plasma endothelin（ET）, calcitonin gene-related peptide（CGRP） and blood flow rate of bilateral vertebral arteries in patients with cervical vertigo（CV） and to assess the effect of ET and CGRP on the onset of CV. Methods：The concentration of ET and CGRP in 64 patients with CV and 30 controls was determined by radioimmunity method. The average blood flow velocity （Vm） of bilateral vertebral arteries was detected by Transcranial Doppler（TCD）. Results：Plasma concen- tration ofET（91.48 ± 9.08 pg/ml） and ET/CGRP ratio value（2.88 ± 0.52） in vertebrobasilar arteriospasm group were both higher than those in vertebrobasilar non-arteriospasm group and in controls, while CGRP concentration（30.66 ± 6.05 pg/ml） in vertebrobasilar arteriospasm group was lower than that in vertebrobasilar non-arteriospasm group and controls respectively. The Vm of bilateral verte- bral arteries in vertebrobasilar arteriospasm group（67.97 ± 11.64 cm/s ） was higher than that in vertebrobasilar non-arteriospasm group and controls respectively, having a positive correlation with ET concentration and ET/CGRP ratio value（r1=0.52, P 〈 0.05; r2=0.59, P 〈 0.05）, but a negative correlation with CGRP concentration（r3=-0.54, P 〈 0.05）. There was no significant difference in ET and CGRP concentration, ET/CGRP ratio value and the Vm of bilateral vertebral arteries between vertebrobasilar non-arteriospasm group and the control group. Conclusion： All the results indicate that ET and CGRP are possibly the most important substance factors at the onset of CV with vertebrobasilar arteriospasm, and their imbalance of regulating vertebrobasilar arterial contraction and relaxation may play an important role in the onset of CV with vertebrobasilar arteriospasm.展开更多
Objective To observe the clinical efficacy of needling Jingjiaji points in combination with acupressure for cervical vertigo, and provide a better therapy. Methods Sixty-five cases of patients with cervical vertigo we...Objective To observe the clinical efficacy of needling Jingjiaji points in combination with acupressure for cervical vertigo, and provide a better therapy. Methods Sixty-five cases of patients with cervical vertigo were punctured on the points Jingjiaji and Fengchi （风池GB 20） bilaterally, from Qiangjian （强间 GV 18） to Naohu （脑户 GV 17）, from Yuzhan （玉枕 BL 9） to Tianzhu （天柱 BL 10） with penetrating methods, besides, acupressure was also used on these points. It was given once a day, and 16 times constituted one course with 2 courses altogether, and then the clinical efficacy was observed. Results Twenty-five cases were cured accounting to 38.5%; 18 remarkably improved accounting to 27.7%; 19 improved accounting to 29.2%; 3 ineffective accounting to 4.6%. The total effective rate was 95.4%. Conclusion Needling Jingjiaji points in combination with acupressure can alleviate the clinical symptoms of cervical vertigo and is worthy of being promoted.展开更多
Objective To observe the clinical efficacy of needling cervical Jiaji points in combination with acupoint pressing for cervical vertigo, and provide a better therapy for the clinical treatment of this disease. Methods...Objective To observe the clinical efficacy of needling cervical Jiaji points in combination with acupoint pressing for cervical vertigo, and provide a better therapy for the clinical treatment of this disease. Methods Sixty-five patients with cervical vertigo were punctured at the points Cervical jiaji and Fengchi （风池 GB 20） bilaterally, from Qiangjian （强间 GV 18） to Naohu （脑户 GV 17）, from Yuzhen （玉枕 BL 9） to Tianzhu （天柱 BL 10） with penetrating methods, besides, acupoint pressing was also used on these points. It was given once a day, and 16 times constituted one course with 2 courses together, and then the clinical efficacy was observed. Results Twenty-five cases were cured accounting to 38.5%; 18 remarkably improved accounting to 27.7%; 19 improved accounting to 29.2%; 3 ineffective accounting to 4.6%. The total effective rate was 95.4%. Conclusion Needling cervical Jiaji points in combination with acupoint pressing can alleviate the clinical symptoms of cervical vertigo and worthy of being promoted.展开更多
The cervical headache and vertigo were treated with acupuncture at Fengchi（GB20）and Wangu（GB 12）and lifting,rotating,pulling-manipulation at neck.The total effective ratewas 91.4％.The therapeutic effects of these...The cervical headache and vertigo were treated with acupuncture at Fengchi（GB20）and Wangu（GB 12）and lifting,rotating,pulling-manipulation at neck.The total effective ratewas 91.4％.The therapeutic effects of these two types,malposition type and osteophytosis type,were studied and compared.The results were significantly different in statistics.展开更多
Objective: To observe the effect of puncturing cervical plexus plus moxibustion in treatment of cervical vertigo. Methods: 78 inpatients were randomly divided into acupuncture + moxibustion (acumoxi) group (n = 40) an...Objective: To observe the effect of puncturing cervical plexus plus moxibustion in treatment of cervical vertigo. Methods: 78 inpatients were randomly divided into acupuncture + moxibustion (acumoxi) group (n = 40) and Western medicine (control) group (n =38). Acupuncture needles were inserted separately into the points about 0. 5 cun beside the spinous processes of the cervical vertebral1-7. Results: The cure rates and total effective rates of acumoxi group and control group were 70.00%, 95.00%, 31 . 58% and 92% respectively, with the cure rate of the acumoxi group being significantly higher than that of control group (P<0.05). After treatment, the mean velocity of blood flow of the vertebral artery and basal artery decreased significantly (P <0.05, 0.01) . Conclusion: Acupuncture of cervical plexus plus moxibustion is effective definitely in treatment of cervical vertigo and superior to that of control group.展开更多
Objective: To observe the therapeutic effect of hydro acupuncture therapy for treatment of vertigo induced by vertebroartery type cervical spondylopathy and to study its action mechanisms. Methods: A total of 54 cases...Objective: To observe the therapeutic effect of hydro acupuncture therapy for treatment of vertigo induced by vertebroartery type cervical spondylopathy and to study its action mechanisms. Methods: A total of 54 cases of vertebroartery type cervical spondylopathy patients were observed in the present study. Fengfu (GV 16) and Jiaji (EX B 2) near the regenerated cervical vertebral body were used for injection of Ligustrazine injectio, 1 mL every acupoint, once every other day, with 7 sessions being a therapeutic course. Before and after treatment, cerebral blood flow volume was determined using a Doppler velocimeter. Results: After 2 weeks’ treatment, of the 54 cases, 28 (51.9%) had their vertigo disappeared, 13 (24.1%) had remarkable improvement, 10 (18.5%) had improvement and 3 (5.5%) failed in the treatment, with an effective rate of 94.5%. After treatment, the peak and mean values of the blood flow velocity of the bilateral vertebral arteries and the basilar artery increased significantly in comparison with pre treatment ( P <0.01). Conclusion: Hydro acupuncture therapy has an obvious therapeutic effect for relieving vertebroartery type vertigo and ameliorating cerebral blood supply.展开更多
Objective:Through the real-world electronic medical record information system,the medical records of patients with cervical vertigo were sorted and statistically analyzed to explore the risk factors of patients with c...Objective:Through the real-world electronic medical record information system,the medical records of patients with cervical vertigo were sorted and statistically analyzed to explore the risk factors of patients with cervical vertigo.Method:Retrospective case-control study was adopted.The general status and accompanying symptoms,medical history,auxiliary examination and other medical records of the patients were subject to statistical analysis,and risk factors were determined from logistic regression analysis.Results:The results of imaging examination showed that the risk of vertigo in patients with abnormal cervical physiological curvature was 2.607 times higher than that in patients with normal cervical physiological curvature,and the risk of vertigo in patients with narrowed intervertebral space was 0.431 times higher than that in patients with normal intervertebral space.Conclusion:There were differences in gender,cervical physiological curvature,intervertebral space and other clinical indexes between patients with cervical vertigo and patients without cervical vertigo.Abnormal cervical physiological curvature and narrowing of intervertebral space were significantly correlated with vertigo.展开更多
Objective:To explore the clinical effect of Yin-yang blending acupuncture with traditional Chinese medicine combined with Banxia Baizhu Tianma Decoction in treating patients with cervical vertigo.Methods:120 patients ...Objective:To explore the clinical effect of Yin-yang blending acupuncture with traditional Chinese medicine combined with Banxia Baizhu Tianma Decoction in treating patients with cervical vertigo.Methods:120 patients with cervical vertigo treated in our hospital were selected,and the acupuncture group and the acupuncture group were divided into 60 cases each according to the order of the patients.The two groups of patients were given basic treatment measures.Xia Baizhu Tianma Decoction was treated,and the control group was given Yin and Yang blending acupuncture.The left and right vertebral arteries(LVA),right vertebral arteries(RVA),and basal arteries(BA)were compared before and after treatment in the two groups.,Clinical symptom score,clinical efficacy.Results:after treatment,the Vm values of LVA,RVA,and BA in the acupuncture group were lower than those in the acupuncture group(P<0.05);after treatment,acupuncture The dizziness,neck and shoulder pain,headache,daily life work,psychological and social adaptability scores of the drug group were higher than those of the acupuncture group(P<0.05);after treatment,the cure rate of the acupuncture group was 42.37%,and the effective rate was 37.29%.The efficiency was 16.95%,the inefficiency was 3.39%,the cure rate in the acupuncture group was 26.32%,the marked efficiency was 35.09%,the effective rate was 29.82%,and the ineffective rate was 8.77%.The clinical efficacy of the acupuncture group was better than that of the acupuncture group(P<0.05).Conclusion:Traditional Chinese medicine Yin-yang reconciliation acupuncture combined with Pinellia Baizhu Tianma Decoction is definitely effective in treating patients with cervical vertigo,and it can effectively improve the clinical symptoms and clinical effects of patients.展开更多
Objective We investigate the mechanism of comp rehensive management in the treatme nt of cervical vertigo through treat ing 15patients with cervical vertigo by ce rvical traction plus computer middl e frequency machin...Objective We investigate the mechanism of comp rehensive management in the treatme nt of cervical vertigo through treat ing 15patients with cervical vertigo by ce rvical traction plus computer middl e frequency machine.Method Sedentary jaw-occiput traction ban d was used.Traction was regulated individually.Traction angle was determin ed according to patients’ force line.Multifunctional comput er machine K88-32I was used after traction.Result10cases were cured completely,4were improved,1showed no any improveme nt.Conclusion cervical traction can increase space between cervical spine and uncinate cervica l joint,relieve congestion and edem a,improved compressed vertebral ar tery and distorted artery.Based on traction,computer middle frequency rein forces therapeutic effects of traction and produces cooperated effects.展开更多
Objective The aim was that prospective study was done on different affect of three different treatment projects in the effect rate, the cause and recurrence rate in 12 months. Methods 183 patients of vertigo caused ce...Objective The aim was that prospective study was done on different affect of three different treatment projects in the effect rate, the cause and recurrence rate in 12 months. Methods 183 patients of vertigo caused cervical syndrome with disturbance of hemorheology and microcirculation divided into three groups. Every group was treated by different treatment project. A group: acupotoment and manipulative reduction; B group: applied drugs of ameliorating microcirculation and reducing blood viscosity; C group: associated therapy of A and B. Results (1)On the effect rate,A and C groups were same(P >0.05),B group was the lowest comparison A and B groups(P<0.001),but on the cure rate of A and B groups,C group was better;(2) On the cause,C group was the shortest comparison A and B groups(P<0.001),B group was the longest comparison A and C groups(P<0.001);(3) On recurrence rate in 12 months, A and C group were same(P >0.05),B group was the highest(P<0.001).Conclusions Comprehensive treatment project may be better on obstinate vertigo caused cervical syndrome comparising with any single treatment therapy.展开更多
Cervical cancer related to human papillomavirus(HPV)is a leading cause of cancer-related mortality among women worldwide.Cancer cells release fragments of their DNA,known as circulating tumor DNA(ctDNA),which can be d...Cervical cancer related to human papillomavirus(HPV)is a leading cause of cancer-related mortality among women worldwide.Cancer cells release fragments of their DNA,known as circulating tumor DNA(ctDNA),which can be detected in bodily fluids.A PubMed search using the terms“ctHPV”or“circulating tumor DNA”and“cervical cancer”,limited to the past ten years,identified 104 articles,complemented by hand-searching for literature addressing medico-legal implications.Studies were evaluated for relevance and methodological quality.Detection and characterization of circulating tumor HPV DNA(ctHPV DNA)have emerged as promising tools for assessing prognosis and disease recurrence in cervical cancer.Detection techniques include polymerase chain reaction(PCR),digital droplet PCR(ddPCR),and next-generation sequencing(NGS).This review summarizes current knowledge on ctHPV DNA in cervical cancer and explores its clinical and medico-legal implications,including management of discordant results,diagnostic errors,liability,and data protection compliance.展开更多
Cervical cancer,a leading malignancy globally,poses a significant threat to women's health,with an estimated 604,000 new cases and 342,000 deaths reported in 2020^([1]).As cervical cancer is closely linked to huma...Cervical cancer,a leading malignancy globally,poses a significant threat to women's health,with an estimated 604,000 new cases and 342,000 deaths reported in 2020^([1]).As cervical cancer is closely linked to human papilloma virus(HPV)infection,early detection relies on HPV screening;however,late-stage prognosis remains poor,underscoring the need for novel diagnostic and therapeutic targets^([2]).展开更多
In May 2018,the Director-General of the World Health Organization(WHO)called for global action to eliminate cervical cancer~1.This call marked the beginning of an ambitious international effort to scale up 3 key strat...In May 2018,the Director-General of the World Health Organization(WHO)called for global action to eliminate cervical cancer~1.This call marked the beginning of an ambitious international effort to scale up 3 key strategies:human papillomavirus(HPV)vaccination,cervical cancer screening,and treatment of precancerous lesions and cancer.Subsequently,the WHO and its partners developed a global strategy to accelerate the reduction of cervical cancer incidence,with an ultimate goal of achieving elimination within the next century.This Global Strategy represents a formal international commitment and is anchored in the 90-70-90 targets to be achieved by 2030.In parallel,several countries have also set national commitments,such as Sweden's pledge to achieve elimination by 2027 and Australia's target of achieving elimination by 2035.展开更多
BACKGROUND The full implementation of the national two-child policy has presented significant challenges in ensuring the safety of pregnant women.AIM To investigate the effect of cervical balloon fluid volume on mater...BACKGROUND The full implementation of the national two-child policy has presented significant challenges in ensuring the safety of pregnant women.AIM To investigate the effect of cervical balloon fluid volume on maternal processes,maternal and infant outcomes,and anxiety during pregnancy.METHODS A total of 100 singleton term pregnancies with cervical maturity induction and anxiety were selected using a lottery method;50 women were included.Cervical balloons were used for all participants.In the control group,80 mL of fluid was injected into both balloons;in the observation group,80 and 100 mL were injected into the vaginal and cervical balloons,respectively.The two groups were compared for cervical maturity,labor duration,anxiety,maternal and infant outcomes,and effects on cervical ripening.RESULTS After treatment,the cervical maturity test(Bishop)score was significantly higher in the observation group(9.76±1.19)than in the control group(7.62±0.83),and the Hamilton Anxiety Scale score was lower in the observation group(7.32±0.85)than in the control group(13.05±1.12).The observation group showed higher rates of natural delivery and lower rates of cesarean section than the control group.The first and total stages of labor were shorter in the observation than in the control group;no significant differences were found in the second and third stages.The incidence of complications was lower in the observation group[1(2.00%)vs 9(18.00%)for complications;49(98.00%)vs 41(82.00%)for non-complications].CONCLUSION The selected fluid volumes to promote cervical maturity and induce labor stabilize maternal mood,increase the natural delivery rate,shorten labor,and improve maternal and infant outcomes.展开更多
As the 30th anniversary of the landmark Beijing Fourth World Conference on Women approaches,the forthcoming 2025 World Women's Summit in Beijing offers a timely platform to reaffirm commitments to women's well...As the 30th anniversary of the landmark Beijing Fourth World Conference on Women approaches,the forthcoming 2025 World Women's Summit in Beijing offers a timely platform to reaffirm commitments to women's well-being worldwide.In alignment with this milestone,Cancer Biology&Medicine is proud to present this special issue dedicated to accelerating the global elimination of cervical cancer.展开更多
Objective:To evaluate the therapeutic effect of Tianma Gouteng Decoction combined with Betahistine Mesylate in patients with posterior circulation ischemic vertigo(PCI).Methods:Eighty-two patients with PCI who visited...Objective:To evaluate the therapeutic effect of Tianma Gouteng Decoction combined with Betahistine Mesylate in patients with posterior circulation ischemic vertigo(PCI).Methods:Eighty-two patients with PCI who visited the hospital from February 2024 to February 2025 were selected as samples and randomly divided into two groups.Group A received Tianma Gouteng Decoction combined with Betahistine Mesylate,while Group B received only Betahistine Mesylate.The efficacy,syndrome scores,hemodynamics,and quality of life indicators were compared between the two groups.Results:The efficacy of PCI treatment in Group A was higher than that in Group B(P<0.05).The syndrome scores in Group A were lower than those in Group B(P<0.05).The peak systolic velocity(PSV)of the basilar artery and left and right vertebral arteries in Group A were higher than those in Group B(P<0.05).The quality of life(SF-36)score in Group A was higher than that in Group B(P<0.05).Conclusion:Tianma Gouteng Decoction combined with Betahistine Mesylate is effective and feasible in the treatment of PCI,with improved hemodynamic indicators and reduced disease scores.展开更多
This editorial explores the potential integration of non-Western medicine into radiotherapy for cervical cancer.While radiotherapy remains a radical treatment for cervical cancer,its associated toxicity and decline in...This editorial explores the potential integration of non-Western medicine into radiotherapy for cervical cancer.While radiotherapy remains a radical treatment for cervical cancer,its associated toxicity and decline in quality of life can significantly impact patients’lives.Currently,most treatments are supportive,with no specific treatment options available in Western medicine.Non-Western medicine,often less toxic and easier to administer,has shown promising results when used alongside radiotherapy for cervical cancer.Despite these potential benefits,challenges such as limited evidence and restricted application areas persist.While non-Western medicines may offer potential improvements in chemoradiotherapy outcomes for cervical cancer,further research is necessary to substantiate these benefits.展开更多
基金Supported by:Department of Science and Technology of Guizhou ProvinceQKHLS[2012]No.049
文摘Objective To observe the effect of three vertigo-stopping needles on the contents of neuropeptide Y （NPY）, endothelin （ET） and calcitonin gene-related peptide （CGRP） in plasma of patients with cervical vertigo, and to explore its mechanism of treatment. Methods One hundred and eighty patients with cervical vertigo were divided into group A [acupuncture at R6nyfng （人迎ST 9） and Fengchi （风池 GB 20）, and frontal line], group B [acupuncture at Jing jiaji （颈夹脊）, GB 20 and Baihui （百会 GV 20）] and group C [intravenous infusion with ligustrazine and oral administration with flunarizine] according to simple randomization, with 60 cases in each group. For the patients in group A and group B, the treatment was conducted once a day, and ten times were considered as one course of treatment. Two days were free of treatment between two courses, and two courses were needed. For the patients in group C, the treatment was conducted for fifteen days. The contents of NPY, ET and CGRP in plasma before and after treatment were detected in patients with cervical vertigo. Results The contents of NPY in plasma of patients in the three groups after treatment were markedly lower than that before treatment （all P〈0.01）, and the differences were not statistically significant when compared the descending degrees among three groups （P〉0.05）. The contents of ET in plasma of patients in the three groups after treatment were markedly lower than that before treatment （P〈0.05, P〈0.01）, the descending degree in group A was greater than that in group B and group C, and the difference was statistically significant （P〈0.O1, P〈O.05）; while the difference was not statistically significant when compared the descending degrees between group B and group C （P〉0.05）. The contents of CGRP in plasma of patients in the three groups after treatment were markedly higher than that before treatment （P〈0.05, P〈O.O1）, the increasing degree in group A was greater than that in group B and group C, and the difference was statistically significant （both P〈0.05）; while the difference was not statistically significant when compared the increasing degrees between group B and group C （P〉0.05）. Conclusion Three vertigo-stopping needles, acupuncture and medication can regulate the contents of NPY, ET and CGRP in plasma of patients with cervical vertigo, while three vertigo-stopping needles is significantly superior to acupuncture and medication in reducing ET and increasing CGRP.
文摘Objective To explore the therapeutic efficacy and mechanism of acupuncture at Lieque （列缺 LU 7） in treatment of cervical vertigo （CV）. Methods Forty CV patients met the inclusion criteria were enrolled and treated with acupuncture at bilateral LU 7 points, once daily with 10 times as a course. The changes of blood flow velocity in bilateral vertebral artery and basilar artery were observed through transcranial doppler sonography （TCD） before treatment, after deqi with acupuncture and after a course of treatment, respectively. The scores and therapeutic efficacy on clinical symptoms were assessed according to CV symptoms and the functional assessment scale as well as the Criteria-for Diagnosis and Curative Effect in TCM Syndromes before treatment and after a course of treatment. Results Before treatment, after deqi and after a course of treatment, the blood flow velocity of basilar artery （BA）, left vertebral artery （LVA） and right vertebral artery （RVA） in 22 patients with a decreased blood flow velocity were respectively 23.20±4.84 vs 26.30 ± 4.17 vs 29.20 ± 4.20 （mm/s, BA）, 21.65 ± 3.62 vs 24.20 ± 2.89 vs 26.40 ± 3.62 （mm/s, LVA） and 21.90±3.04 vs 24.25±3.01 vs 26.50_±3.95 （mm/s, RVA）, while in 18 patients with an increased blood flow velocity were respectively 39.94 ± 8.24 vs 35.17 ± 4.84 vs 32.06 ± 3.49 （mm/s, BA）, 41.83 ± 5.64 vs 37.28 ± 2.32 vs 35.61 ± 2.09 （mm/s, LVA） and 37.11 ± 9.83 vs 32.22 ± 6.13 vs 28.11 ± 4.12 （mm/s, RVA）. Except that the difference of blood flow velocity of RVA was not significant in patients with an increased blood flow velocity before treatment and after deqi （P 〉 0.05）, the Vm of all vessels in 40 patients was improved after deqi with acupuncture and a course of treatment （P〈0.01, P〈0.05）. According to CV symptoms and the functional assessment scale, before treatment and after a course of treatment, the scores were 15.68 ± 5.35 and 26.30 ± 3.76, respectively, indicating that after a course of treatment, the symptoms were significantly improved （P 〈 0.01）. According to the Criteria for Diagnosis and Curative E.f]ect in TCM Syndromes, after a course of treatment, the total effective rate was 100% （40/40） and the cured rate was 55.0% （22/40）. Conclusion Acupuncture at LU 7 not only improves the blood supply of vertebral-basilar artery in CV patients, but also has a significant curative effect on improving the clinical symptoms.
文摘Objective： To investigate the relationship among plasma endothelin（ET）, calcitonin gene-related peptide（CGRP） and blood flow rate of bilateral vertebral arteries in patients with cervical vertigo（CV） and to assess the effect of ET and CGRP on the onset of CV. Methods：The concentration of ET and CGRP in 64 patients with CV and 30 controls was determined by radioimmunity method. The average blood flow velocity （Vm） of bilateral vertebral arteries was detected by Transcranial Doppler（TCD）. Results：Plasma concen- tration ofET（91.48 ± 9.08 pg/ml） and ET/CGRP ratio value（2.88 ± 0.52） in vertebrobasilar arteriospasm group were both higher than those in vertebrobasilar non-arteriospasm group and in controls, while CGRP concentration（30.66 ± 6.05 pg/ml） in vertebrobasilar arteriospasm group was lower than that in vertebrobasilar non-arteriospasm group and controls respectively. The Vm of bilateral verte- bral arteries in vertebrobasilar arteriospasm group（67.97 ± 11.64 cm/s ） was higher than that in vertebrobasilar non-arteriospasm group and controls respectively, having a positive correlation with ET concentration and ET/CGRP ratio value（r1=0.52, P 〈 0.05; r2=0.59, P 〈 0.05）, but a negative correlation with CGRP concentration（r3=-0.54, P 〈 0.05）. There was no significant difference in ET and CGRP concentration, ET/CGRP ratio value and the Vm of bilateral vertebral arteries between vertebrobasilar non-arteriospasm group and the control group. Conclusion： All the results indicate that ET and CGRP are possibly the most important substance factors at the onset of CV with vertebrobasilar arteriospasm, and their imbalance of regulating vertebrobasilar arterial contraction and relaxation may play an important role in the onset of CV with vertebrobasilar arteriospasm.
文摘Objective To observe the clinical efficacy of needling Jingjiaji points in combination with acupressure for cervical vertigo, and provide a better therapy. Methods Sixty-five cases of patients with cervical vertigo were punctured on the points Jingjiaji and Fengchi （风池GB 20） bilaterally, from Qiangjian （强间 GV 18） to Naohu （脑户 GV 17）, from Yuzhan （玉枕 BL 9） to Tianzhu （天柱 BL 10） with penetrating methods, besides, acupressure was also used on these points. It was given once a day, and 16 times constituted one course with 2 courses altogether, and then the clinical efficacy was observed. Results Twenty-five cases were cured accounting to 38.5%; 18 remarkably improved accounting to 27.7%; 19 improved accounting to 29.2%; 3 ineffective accounting to 4.6%. The total effective rate was 95.4%. Conclusion Needling Jingjiaji points in combination with acupressure can alleviate the clinical symptoms of cervical vertigo and is worthy of being promoted.
文摘Objective To observe the clinical efficacy of needling cervical Jiaji points in combination with acupoint pressing for cervical vertigo, and provide a better therapy for the clinical treatment of this disease. Methods Sixty-five patients with cervical vertigo were punctured at the points Cervical jiaji and Fengchi （风池 GB 20） bilaterally, from Qiangjian （强间 GV 18） to Naohu （脑户 GV 17）, from Yuzhen （玉枕 BL 9） to Tianzhu （天柱 BL 10） with penetrating methods, besides, acupoint pressing was also used on these points. It was given once a day, and 16 times constituted one course with 2 courses together, and then the clinical efficacy was observed. Results Twenty-five cases were cured accounting to 38.5%; 18 remarkably improved accounting to 27.7%; 19 improved accounting to 29.2%; 3 ineffective accounting to 4.6%. The total effective rate was 95.4%. Conclusion Needling cervical Jiaji points in combination with acupoint pressing can alleviate the clinical symptoms of cervical vertigo and worthy of being promoted.
文摘The cervical headache and vertigo were treated with acupuncture at Fengchi（GB20）and Wangu（GB 12）and lifting,rotating,pulling-manipulation at neck.The total effective ratewas 91.4％.The therapeutic effects of these two types,malposition type and osteophytosis type,were studied and compared.The results were significantly different in statistics.
文摘Objective: To observe the effect of puncturing cervical plexus plus moxibustion in treatment of cervical vertigo. Methods: 78 inpatients were randomly divided into acupuncture + moxibustion (acumoxi) group (n = 40) and Western medicine (control) group (n =38). Acupuncture needles were inserted separately into the points about 0. 5 cun beside the spinous processes of the cervical vertebral1-7. Results: The cure rates and total effective rates of acumoxi group and control group were 70.00%, 95.00%, 31 . 58% and 92% respectively, with the cure rate of the acumoxi group being significantly higher than that of control group (P<0.05). After treatment, the mean velocity of blood flow of the vertebral artery and basal artery decreased significantly (P <0.05, 0.01) . Conclusion: Acupuncture of cervical plexus plus moxibustion is effective definitely in treatment of cervical vertigo and superior to that of control group.
文摘Objective: To observe the therapeutic effect of hydro acupuncture therapy for treatment of vertigo induced by vertebroartery type cervical spondylopathy and to study its action mechanisms. Methods: A total of 54 cases of vertebroartery type cervical spondylopathy patients were observed in the present study. Fengfu (GV 16) and Jiaji (EX B 2) near the regenerated cervical vertebral body were used for injection of Ligustrazine injectio, 1 mL every acupoint, once every other day, with 7 sessions being a therapeutic course. Before and after treatment, cerebral blood flow volume was determined using a Doppler velocimeter. Results: After 2 weeks’ treatment, of the 54 cases, 28 (51.9%) had their vertigo disappeared, 13 (24.1%) had remarkable improvement, 10 (18.5%) had improvement and 3 (5.5%) failed in the treatment, with an effective rate of 94.5%. After treatment, the peak and mean values of the blood flow velocity of the bilateral vertebral arteries and the basilar artery increased significantly in comparison with pre treatment ( P <0.01). Conclusion: Hydro acupuncture therapy has an obvious therapeutic effect for relieving vertebroartery type vertigo and ameliorating cerebral blood supply.
基金supported by Health Research Fund of Shaanxi Province(No.:2018D018).
文摘Objective:Through the real-world electronic medical record information system,the medical records of patients with cervical vertigo were sorted and statistically analyzed to explore the risk factors of patients with cervical vertigo.Method:Retrospective case-control study was adopted.The general status and accompanying symptoms,medical history,auxiliary examination and other medical records of the patients were subject to statistical analysis,and risk factors were determined from logistic regression analysis.Results:The results of imaging examination showed that the risk of vertigo in patients with abnormal cervical physiological curvature was 2.607 times higher than that in patients with normal cervical physiological curvature,and the risk of vertigo in patients with narrowed intervertebral space was 0.431 times higher than that in patients with normal intervertebral space.Conclusion:There were differences in gender,cervical physiological curvature,intervertebral space and other clinical indexes between patients with cervical vertigo and patients without cervical vertigo.Abnormal cervical physiological curvature and narrowing of intervertebral space were significantly correlated with vertigo.
基金2019 Hainan provincial health industry research project(No.178)
文摘Objective:To explore the clinical effect of Yin-yang blending acupuncture with traditional Chinese medicine combined with Banxia Baizhu Tianma Decoction in treating patients with cervical vertigo.Methods:120 patients with cervical vertigo treated in our hospital were selected,and the acupuncture group and the acupuncture group were divided into 60 cases each according to the order of the patients.The two groups of patients were given basic treatment measures.Xia Baizhu Tianma Decoction was treated,and the control group was given Yin and Yang blending acupuncture.The left and right vertebral arteries(LVA),right vertebral arteries(RVA),and basal arteries(BA)were compared before and after treatment in the two groups.,Clinical symptom score,clinical efficacy.Results:after treatment,the Vm values of LVA,RVA,and BA in the acupuncture group were lower than those in the acupuncture group(P<0.05);after treatment,acupuncture The dizziness,neck and shoulder pain,headache,daily life work,psychological and social adaptability scores of the drug group were higher than those of the acupuncture group(P<0.05);after treatment,the cure rate of the acupuncture group was 42.37%,and the effective rate was 37.29%.The efficiency was 16.95%,the inefficiency was 3.39%,the cure rate in the acupuncture group was 26.32%,the marked efficiency was 35.09%,the effective rate was 29.82%,and the ineffective rate was 8.77%.The clinical efficacy of the acupuncture group was better than that of the acupuncture group(P<0.05).Conclusion:Traditional Chinese medicine Yin-yang reconciliation acupuncture combined with Pinellia Baizhu Tianma Decoction is definitely effective in treating patients with cervical vertigo,and it can effectively improve the clinical symptoms and clinical effects of patients.
文摘Objective We investigate the mechanism of comp rehensive management in the treatme nt of cervical vertigo through treat ing 15patients with cervical vertigo by ce rvical traction plus computer middl e frequency machine.Method Sedentary jaw-occiput traction ban d was used.Traction was regulated individually.Traction angle was determin ed according to patients’ force line.Multifunctional comput er machine K88-32I was used after traction.Result10cases were cured completely,4were improved,1showed no any improveme nt.Conclusion cervical traction can increase space between cervical spine and uncinate cervica l joint,relieve congestion and edem a,improved compressed vertebral ar tery and distorted artery.Based on traction,computer middle frequency rein forces therapeutic effects of traction and produces cooperated effects.
文摘Objective The aim was that prospective study was done on different affect of three different treatment projects in the effect rate, the cause and recurrence rate in 12 months. Methods 183 patients of vertigo caused cervical syndrome with disturbance of hemorheology and microcirculation divided into three groups. Every group was treated by different treatment project. A group: acupotoment and manipulative reduction; B group: applied drugs of ameliorating microcirculation and reducing blood viscosity; C group: associated therapy of A and B. Results (1)On the effect rate,A and C groups were same(P >0.05),B group was the lowest comparison A and B groups(P<0.001),but on the cure rate of A and B groups,C group was better;(2) On the cause,C group was the shortest comparison A and B groups(P<0.001),B group was the longest comparison A and C groups(P<0.001);(3) On recurrence rate in 12 months, A and C group were same(P >0.05),B group was the highest(P<0.001).Conclusions Comprehensive treatment project may be better on obstinate vertigo caused cervical syndrome comparising with any single treatment therapy.
文摘Cervical cancer related to human papillomavirus(HPV)is a leading cause of cancer-related mortality among women worldwide.Cancer cells release fragments of their DNA,known as circulating tumor DNA(ctDNA),which can be detected in bodily fluids.A PubMed search using the terms“ctHPV”or“circulating tumor DNA”and“cervical cancer”,limited to the past ten years,identified 104 articles,complemented by hand-searching for literature addressing medico-legal implications.Studies were evaluated for relevance and methodological quality.Detection and characterization of circulating tumor HPV DNA(ctHPV DNA)have emerged as promising tools for assessing prognosis and disease recurrence in cervical cancer.Detection techniques include polymerase chain reaction(PCR),digital droplet PCR(ddPCR),and next-generation sequencing(NGS).This review summarizes current knowledge on ctHPV DNA in cervical cancer and explores its clinical and medico-legal implications,including management of discordant results,diagnostic errors,liability,and data protection compliance.
基金supported by a project funded by the Hebei Provincial Central Guidance Local Science and Technology Development Fund(236Z7714G)。
文摘Cervical cancer,a leading malignancy globally,poses a significant threat to women's health,with an estimated 604,000 new cases and 342,000 deaths reported in 2020^([1]).As cervical cancer is closely linked to human papilloma virus(HPV)infection,early detection relies on HPV screening;however,late-stage prognosis remains poor,underscoring the need for novel diagnostic and therapeutic targets^([2]).
基金supported by the CAMS Innovation Fund for Medical Sciences(No.2023-I2M-3-019)National Natural Science Foundation of China(No.82404366)。
文摘In May 2018,the Director-General of the World Health Organization(WHO)called for global action to eliminate cervical cancer~1.This call marked the beginning of an ambitious international effort to scale up 3 key strategies:human papillomavirus(HPV)vaccination,cervical cancer screening,and treatment of precancerous lesions and cancer.Subsequently,the WHO and its partners developed a global strategy to accelerate the reduction of cervical cancer incidence,with an ultimate goal of achieving elimination within the next century.This Global Strategy represents a formal international commitment and is anchored in the 90-70-90 targets to be achieved by 2030.In parallel,several countries have also set national commitments,such as Sweden's pledge to achieve elimination by 2027 and Australia's target of achieving elimination by 2035.
基金Supported by the Wuxi Municipal Health Commission Maternal and Child Health Research Project,No.FYKY202202.
文摘BACKGROUND The full implementation of the national two-child policy has presented significant challenges in ensuring the safety of pregnant women.AIM To investigate the effect of cervical balloon fluid volume on maternal processes,maternal and infant outcomes,and anxiety during pregnancy.METHODS A total of 100 singleton term pregnancies with cervical maturity induction and anxiety were selected using a lottery method;50 women were included.Cervical balloons were used for all participants.In the control group,80 mL of fluid was injected into both balloons;in the observation group,80 and 100 mL were injected into the vaginal and cervical balloons,respectively.The two groups were compared for cervical maturity,labor duration,anxiety,maternal and infant outcomes,and effects on cervical ripening.RESULTS After treatment,the cervical maturity test(Bishop)score was significantly higher in the observation group(9.76±1.19)than in the control group(7.62±0.83),and the Hamilton Anxiety Scale score was lower in the observation group(7.32±0.85)than in the control group(13.05±1.12).The observation group showed higher rates of natural delivery and lower rates of cesarean section than the control group.The first and total stages of labor were shorter in the observation than in the control group;no significant differences were found in the second and third stages.The incidence of complications was lower in the observation group[1(2.00%)vs 9(18.00%)for complications;49(98.00%)vs 41(82.00%)for non-complications].CONCLUSION The selected fluid volumes to promote cervical maturity and induce labor stabilize maternal mood,increase the natural delivery rate,shorten labor,and improve maternal and infant outcomes.
文摘As the 30th anniversary of the landmark Beijing Fourth World Conference on Women approaches,the forthcoming 2025 World Women's Summit in Beijing offers a timely platform to reaffirm commitments to women's well-being worldwide.In alignment with this milestone,Cancer Biology&Medicine is proud to present this special issue dedicated to accelerating the global elimination of cervical cancer.
文摘Objective:To evaluate the therapeutic effect of Tianma Gouteng Decoction combined with Betahistine Mesylate in patients with posterior circulation ischemic vertigo(PCI).Methods:Eighty-two patients with PCI who visited the hospital from February 2024 to February 2025 were selected as samples and randomly divided into two groups.Group A received Tianma Gouteng Decoction combined with Betahistine Mesylate,while Group B received only Betahistine Mesylate.The efficacy,syndrome scores,hemodynamics,and quality of life indicators were compared between the two groups.Results:The efficacy of PCI treatment in Group A was higher than that in Group B(P<0.05).The syndrome scores in Group A were lower than those in Group B(P<0.05).The peak systolic velocity(PSV)of the basilar artery and left and right vertebral arteries in Group A were higher than those in Group B(P<0.05).The quality of life(SF-36)score in Group A was higher than that in Group B(P<0.05).Conclusion:Tianma Gouteng Decoction combined with Betahistine Mesylate is effective and feasible in the treatment of PCI,with improved hemodynamic indicators and reduced disease scores.
文摘This editorial explores the potential integration of non-Western medicine into radiotherapy for cervical cancer.While radiotherapy remains a radical treatment for cervical cancer,its associated toxicity and decline in quality of life can significantly impact patients’lives.Currently,most treatments are supportive,with no specific treatment options available in Western medicine.Non-Western medicine,often less toxic and easier to administer,has shown promising results when used alongside radiotherapy for cervical cancer.Despite these potential benefits,challenges such as limited evidence and restricted application areas persist.While non-Western medicines may offer potential improvements in chemoradiotherapy outcomes for cervical cancer,further research is necessary to substantiate these benefits.
