In this paper, an efficient shrinkage estimation procedure for the partially linear varying coefficient model (PLVC) with random effect is considered. By selecting the significant variable and estimating the nonzero c...In this paper, an efficient shrinkage estimation procedure for the partially linear varying coefficient model (PLVC) with random effect is considered. By selecting the significant variable and estimating the nonzero coefficient, the model structure specification is accomplished by introducing a novel penalized estimating equation. Under some mild conditions, the asymptotic properties for the proposed model selection and estimation results, such as the sparsity and oracle property, are established. Some numerical simulation studies and a real data analysis are presented to examine the finite sample performance of the procedure.展开更多
The consideration of the time-varying covariate and time-varying coefficient effect in survival models are plausible and robust techniques. Such kind of analysis can be carried out with a general class of semiparametr...The consideration of the time-varying covariate and time-varying coefficient effect in survival models are plausible and robust techniques. Such kind of analysis can be carried out with a general class of semiparametric transformation models. The aim of this article is to develop modified estimating equations under semiparametric transformation models of survival time with time-varying coefficient effect and time-varying continuous covariates. For this, it is important to organize the data in a counting process style and transform the time with standard transformation classes which shall be applied in this article. In the situation when the effect of coefficient and covariates change over time, the widely used maximum likelihood estimation method becomes more complex and burdensome in estimating consistent estimates. To overcome this problem, alternatively, the modified estimating equations were applied to estimate the unknown parameters and unspecified monotone transformation functions. The estimating equations were modified to incorporate the time-varying effect in both coefficient and covariates. The performance of the proposed methods is tested through a simulation study. To sum up the study, the effect of possibly time-varying covariates and time-varying coefficients was evaluated in some special cases of semiparametric transformation models. Finally, the results have shown that the role of the time-varying covariate in the semiparametric transformation models was plausible and credible.展开更多
In this paper, we study the sure independence screening of ultrahigh-dimensional censored data with varying coefficient single-index model. This general model framework covers a large number of commonly used survival ...In this paper, we study the sure independence screening of ultrahigh-dimensional censored data with varying coefficient single-index model. This general model framework covers a large number of commonly used survival models. The property that the proposed method is not derived for a specific model is appealing in ultrahigh dimensional regressions, as it is difficult to specify a correct model for ultrahigh dimensional predictors.Once the assuming data generating process does not meet the actual one, the screening method based on the model will be problematic. We establish the sure screening property and consistency in ranking property of the proposed method. Simulations are conducted to study the finite sample performances, and the results demonstrate that the proposed method is competitive compared with the existing methods. We also illustrate the results via the analysis of data from The National Alzheimers Coordinating Center(NACC).展开更多
In this paper, the parameters of a p-dimensional linear structural EV(error-in-variable)model are estimated when the coefficients vary with a real variable and the model error is time series.The adjust weighted least ...In this paper, the parameters of a p-dimensional linear structural EV(error-in-variable)model are estimated when the coefficients vary with a real variable and the model error is time series.The adjust weighted least squares(AWLS) method is used to estimate the parameters. It is shown that the estimators are weakly consistent and asymptotically normal, and the optimal convergence rate is also obtained. Simulations study are undertaken to illustrate our AWLSEs have good performance.展开更多
本文基于因果推断理论,提出根据病人的生物标记物进行最优治疗方案选择的统计方法.这种方法是基于CATE(conditional average treatment effect)曲线以及CATE曲线的置信带(SCB)的.CSTE曲线表示给定生物标记物(协变量)的条件下,处理组的...本文基于因果推断理论,提出根据病人的生物标记物进行最优治疗方案选择的统计方法.这种方法是基于CATE(conditional average treatment effect)曲线以及CATE曲线的置信带(SCB)的.CSTE曲线表示给定生物标记物(协变量)的条件下,处理组的条件平均处理效应.同时,CATE曲线及其SCB可以被用于对特定的治疗方案选择适宜的病人.文中利用B样条方法估计CATE曲线及其CSB,并推导了其近似大样本性质.文中还通过模拟比较研究了CATE曲线的置信带的有限样本性质,并阐述了CATE曲线及其置信带在真实数据中如何选择最优治疗方案.展开更多
文摘In this paper, an efficient shrinkage estimation procedure for the partially linear varying coefficient model (PLVC) with random effect is considered. By selecting the significant variable and estimating the nonzero coefficient, the model structure specification is accomplished by introducing a novel penalized estimating equation. Under some mild conditions, the asymptotic properties for the proposed model selection and estimation results, such as the sparsity and oracle property, are established. Some numerical simulation studies and a real data analysis are presented to examine the finite sample performance of the procedure.
文摘The consideration of the time-varying covariate and time-varying coefficient effect in survival models are plausible and robust techniques. Such kind of analysis can be carried out with a general class of semiparametric transformation models. The aim of this article is to develop modified estimating equations under semiparametric transformation models of survival time with time-varying coefficient effect and time-varying continuous covariates. For this, it is important to organize the data in a counting process style and transform the time with standard transformation classes which shall be applied in this article. In the situation when the effect of coefficient and covariates change over time, the widely used maximum likelihood estimation method becomes more complex and burdensome in estimating consistent estimates. To overcome this problem, alternatively, the modified estimating equations were applied to estimate the unknown parameters and unspecified monotone transformation functions. The estimating equations were modified to incorporate the time-varying effect in both coefficient and covariates. The performance of the proposed methods is tested through a simulation study. To sum up the study, the effect of possibly time-varying covariates and time-varying coefficients was evaluated in some special cases of semiparametric transformation models. Finally, the results have shown that the role of the time-varying covariate in the semiparametric transformation models was plausible and credible.
基金Supported by the National Natural Science Foundation of China(No.11801567)
文摘In this paper, we study the sure independence screening of ultrahigh-dimensional censored data with varying coefficient single-index model. This general model framework covers a large number of commonly used survival models. The property that the proposed method is not derived for a specific model is appealing in ultrahigh dimensional regressions, as it is difficult to specify a correct model for ultrahigh dimensional predictors.Once the assuming data generating process does not meet the actual one, the screening method based on the model will be problematic. We establish the sure screening property and consistency in ranking property of the proposed method. Simulations are conducted to study the finite sample performances, and the results demonstrate that the proposed method is competitive compared with the existing methods. We also illustrate the results via the analysis of data from The National Alzheimers Coordinating Center(NACC).
基金Supported by the Educational Commission of Hubei Province of China(Grant No.D20112503)National Natural Science Foundation of China(Grant Nos.11071022,11231010 and 11028103)the foundation of Beijing Center of Mathematics and Information Sciences
文摘In this paper, the parameters of a p-dimensional linear structural EV(error-in-variable)model are estimated when the coefficients vary with a real variable and the model error is time series.The adjust weighted least squares(AWLS) method is used to estimate the parameters. It is shown that the estimators are weakly consistent and asymptotically normal, and the optimal convergence rate is also obtained. Simulations study are undertaken to illustrate our AWLSEs have good performance.
基金supported by the National Natural Science Foundataion of China(Grant No.81773546)。
文摘本文基于因果推断理论,提出根据病人的生物标记物进行最优治疗方案选择的统计方法.这种方法是基于CATE(conditional average treatment effect)曲线以及CATE曲线的置信带(SCB)的.CSTE曲线表示给定生物标记物(协变量)的条件下,处理组的条件平均处理效应.同时,CATE曲线及其SCB可以被用于对特定的治疗方案选择适宜的病人.文中利用B样条方法估计CATE曲线及其CSB,并推导了其近似大样本性质.文中还通过模拟比较研究了CATE曲线的置信带的有限样本性质,并阐述了CATE曲线及其置信带在真实数据中如何选择最优治疗方案.
