A new breeding population of Mandarin Duck （Aix gaIericulata, Linnaeus） was first recorded in 2003 in Jiao- tanzhuang-Hehekou region of Pingshan county, Hebei Province, China. Recently, the gradually increasing popu...A new breeding population of Mandarin Duck （Aix gaIericulata, Linnaeus） was first recorded in 2003 in Jiao- tanzhuang-Hehekou region of Pingshan county, Hebei Province, China. Recently, the gradually increasing population indicates that there are suitable breeding habitats （such as foraging habitats and nesting sites） for Mandarin Duck. However, these habitats are always close to human disturbances, which are the potential risk for their population. Therefore, it is urgent to put forward an applicable protection strategy, in order to strengthen the public awareness for this unprotected population.展开更多
Highly enantioselective Rh-catalyzed partial hydrogenation of unprotected simple 2-alkyl-5-aryl-disubstituted pyrroles has been successfully developed,generating a series of chiral 1-pyrroline derivatives generally wi...Highly enantioselective Rh-catalyzed partial hydrogenation of unprotected simple 2-alkyl-5-aryl-disubstituted pyrroles has been successfully developed,generating a series of chiral 1-pyrroline derivatives generally with excellent results(95%-99%yields,91%-96%ee).Moreover,2,5-aryl-1H-pyrroles were hydrogenated well in high yields and good enantioselectivities.This efficient protocol features easily accessible substrates,wide substrate scope,well functional group compatibility,commercially available rhodium precursor and chiral ligand.It provides a versatile route to access chiral 1-pyrroline derivatives that are of great importance in organic synthesis and pharmaceutical chemistry.展开更多
The Yi are the largest and most disadvantaged ethnic minority population in southwestern China. This region contains over eight million Yi, with approximately 2.4 million living in the Liangshan Yi Autonomous Prefectu...The Yi are the largest and most disadvantaged ethnic minority population in southwestern China. This region contains over eight million Yi, with approximately 2.4 million living in the Liangshan Yi Autonomous Prefecture （Liangshan） in Sichuan Province. Liangshan is located along one of the main drug trafficking routes from the ＇Golden Triangle＇ to northwest and central China, making it one of the largest illicit drug production and distribution centers in China.展开更多
Background: Percutaneous coronary intervention (PCI) has been increasingly employed to treat unprotected left main (ULM) stenosis, with hard endpoints similar to by-pass surgery, in patients selected by a Heart Team. ...Background: Percutaneous coronary intervention (PCI) has been increasingly employed to treat unprotected left main (ULM) stenosis, with hard endpoints similar to by-pass surgery, in patients selected by a Heart Team. Methods: From January 2008 to December 2011, 317 unselected and consecutive patients with de novo ULM stenosis underwent PCI with both bare metal (BMS) and drug-eluting (DES) stents. Major adverse cardiovascular events, target lesion (TLR) and vessel (TVR) revascularization were evaluated over a mean period of 590 ± 371 days. Results: Our population was characterized by a mean age 72 ± 10 years, high rate of acute coronary syndrome (ACS) (either with ST or non-ST elevation myocardial infarction, 15.5% and 35% respectively), severe comorbidity 16%, mean Euroscore 7 ± 3, mean Syntax Score 25 ± 9. In-hospital mortality was 6%. During the follow-up period, all-cause mortality was 16.7%, falling to 7% at the end of the follow-up, excluding patients presenting with ACS. TLR was observed and treated in 15% of patients. BMS utilization, age >75 years, ACS indication, Syntax Score >32 and associated peripheral artery disease were independent predictors of mortality at multivariate analysis. Conclusions: Stenting of ULM stenosis appears to be associated with a favorable mid-term outcome, even in an unselected population.展开更多
Objective: to explore the effect of unprotected perineal delivery in delivery room nursing. Methods: 60 cases of puerpera in our hospital were randomly divided into two groups. Observation group without protection per...Objective: to explore the effect of unprotected perineal delivery in delivery room nursing. Methods: 60 cases of puerpera in our hospital were randomly divided into two groups. Observation group without protection perineal midwifing nursing, control group routine nursing, compare its curative effect. Results: the observation group was significantly better than the control group in terms of perineal laceration, integrity, blood loss after delivery and satisfaction, P<0.05. Conclusion: unprotected perineal delivery is better.展开更多
Objective: to analyze the effectiveness of this method of helping pregnant women during pregnancy and childbirth. We selected the testing method for the first delivery in our hospital from January 2020 to January 2021...Objective: to analyze the effectiveness of this method of helping pregnant women during pregnancy and childbirth. We selected the testing method for the first delivery in our hospital from January 2020 to January 2021. A total of 60 cases were selected. Then all the infants were divided into two groups: observation group and control group with 30 cases each. The control group used traditional obstetric methods, while the observation group used unprotected obstetric methods. The frontal lobe ratio, pain degree, delivery time and bleeding degree of the two groups were compared. The comparative results show that the frontal lobe truncation rate of parturients in this group is significantly lower than that of the control group 14 (46.67%), and this group has maternal pain index (3.43%). In the case of maternal pain (5.73±1.34), duration of labor (643.15±49.3) and hemorrhage (341.7±16.27), the indicators of duration of labor (462.42±57.1) and hemorrhage (219.3±13.19) were also better than those of the control group. The difference of 16.27 between the two groups was statistically significant (P < 0.05). Conclusion: the use of untreated obstetric services for vaginal delivery of the first child in our hospital can effectively reduce the postpartum screening rate, shorten the delivery time of the parturient and relieve the pain of the mother, which is beneficial to the postpartum recovery of the mother and can be widely disseminated in clinical clinics.展开更多
Objective:This paper mainly explores the application value of unprotected midwifery care for primipara natural childbirth.Methods:120 primiparas in our hospital from January 2017 to February 2019 were divided into rou...Objective:This paper mainly explores the application value of unprotected midwifery care for primipara natural childbirth.Methods:120 primiparas in our hospital from January 2017 to February 2019 were divided into routine group and Research Group,60 cases in each group.The routine group was given routine perineal protection midwifery,and the Research Group was given routine midwifery nursing.The nursing intervention effects of the two groups were compared statistically.Results:After statistics,VAS score and bleeding volume of perineal pain in the Research Group were lower than those in the conventional group,and the length of hospital stay in the Research Group was less than that in the conventional group,P<0.05;There was no significant difference in the time of the first stage of labor,the second stage of labor and the third stage of labor between the Research Group and the conventional group(P>0.05);The incidence of complications in the Research Group was lower than that in the conventional group(P<0.05).Conclusion:The application value of unprotected midwifery nursing intervention in primipara natural childbirth is significant.展开更多
Objective: to explore the influence of unprotected perineal delivery in delivery room nursing. Methods: the selection time was from January 2020 to January 2021, and the subjects were parturients who delivered natural...Objective: to explore the influence of unprotected perineal delivery in delivery room nursing. Methods: the selection time was from January 2020 to January 2021, and the subjects were parturients who delivered naturally through vagina. The above 100 parturients were divided into control group and experimental group by drawing lots, with 50 cases in each group. The control group was given the traditional delivery method, and the experimental group was given the unprotected perineal delivery method. The degree of perineal laceration, the time of the second stage of labor, the total amount of bleeding and the quality of life three months after delivery were compared between the two groups. Results: the degree of perineal laceration in the experimental group was lower than that in the control group (P < 0.05), and the data comparison was statistically significant. The duration of the second stage of labor and the amount of blood loss in the experimental group were less than those in the control group (P < 0.05), and the difference was statistically significant. 3months after delivery, two kinds of postpartum quality of life were investigated. The score of the experimental group was higher than that of the control group (P < 0.05), and the data difference is of comparative significance. Conclusion: unprotected perineal delivery method has less perineal damage to pregnant women, and is helpful to improve the quality of life of pregnant women after delivery. It is worthy of popularization and application.展开更多
Objective: to study the value of unprotected midwifery in pregnant women's natural childbirth. Methods: according to our hospital in recent years admitted to the maternal as the research object of a total of 100 c...Objective: to study the value of unprotected midwifery in pregnant women's natural childbirth. Methods: according to our hospital in recent years admitted to the maternal as the research object of a total of 100 cases, according to the nursing model they were divided into two groups, each group of 50 cases, the control group using unprotected care model, the experimental group using traditional care model, observe the clinical experimental results of the two groups, the experimental results were analyzed. Results: the amount of vaginal bleeding, pain during delivery and hospital stay in the observation group were much lower than those in the control group. During the primary natural delivery of the parturient, the unprotected nursing can greatly shorten the delivery time, reduce the amount of vaginal bleeding, relieve the pain during delivery and reduce the complications after delivery. It has good clinical application and can be popularized. Conclusion: unprotected midwifery nursing in primipara's natural childbirth can effectively reduce the delivery time, reduce the amount of vaginal bleeding, and also can relieve the pain symptoms of childbirth, thus reducing postpartum complications.展开更多
Background： There are limited data on longer-term outcomes （〉5 years） for patients with unprotected left main coronary artery （ULMCA） disease who underwent percutaneous coronary intervention （PCI） in the drug-...Background： There are limited data on longer-term outcomes （〉5 years） for patients with unprotected left main coronary artery （ULMCA） disease who underwent percutaneous coronary intervention （PCI） in the drug-eluting stents （DES） era. This study aimed at comparing the long-term （〉5 years） outcomes of patients with ULMCA disease underwent PCI with DES and coronary artery bypass grafting （CABG） and the predictors of adverse events. Methods： All consecutive patients with ULMCA disease treated with DES implantation versus CABG in our center, between January 2003 and July 2009, were screened for analyzing. A propensity score analysis was carried out to adjust for potential confounding between the two groups. Results： Nine hundred and twenty-two patients with ULMCA disease were enrolled for the analyses （DES = 465 vs. CABG = 457）. During the median follow-up of 7.1 years （interquartile range 5.3-8.2 years）, no difference was found between PCI and CABG in the occurrence of death （P = 0.282） and the composite endpoint of cardiac death, myocardial infarction （MI） and stroke （P = 0.294）. Rates of major adverse cardiac and cerebrovascular events were significantly higher in the PCI group （P = 0.014） in large part because of the significantly higher rate of repeat revascularization （P 〈 0.001）. PC/was correlated with the lower occurrence of stroke （P = 0.004）. Multivariate analysis showed ejection fraction （EF） （P = 0.012）, creatinine （P = 0.016）, and prior stroke （P = 0.03 l） were independent predictors of the composite endpoint of cardiac death, MI, and stroke in the DES group, while age （P = 0.026） and EF （P = 0.002） were independent predictors in the CABG group. Conclusions： During a median follow-up of 7.1 years, there was no difference in the rate of death between PCI with DES implantation and CABG in ULMCA lesions in the patient cohort. CABG group was observed to have significantly lower rates of repeat revascularization but higher stroke rates compared with PCI. EF, creatinine, and prior stroke were independent predictors of the composite endpoint of cardiac death, MI, and stroke in the DES group, while age and EF were independent predictors in the CABG group.展开更多
Background Implantation of either bare metal stent （BMS） or drug-eluting stent （DES） has been used in every day practice for patients with unprotected left main stenosis （UPLMS）. There are still a lack of data r...Background Implantation of either bare metal stent （BMS） or drug-eluting stent （DES） has been used in every day practice for patients with unprotected left main stenosis （UPLMS）. There are still a lack of data regading the subsequent results of UPLMS in-stent restenosis （ISR）. The present study aimed at determing the clinical outcome of UPLMS ISR patients after implantation of either BMS or DES.Methods Patients with UPLMS ISR after stenting were included. The primary endpoint was the cumulative major adverse cardiac events （MACE）, including cardiac death, myocardial infarction （Ml）, and target vessel revascularization （TVR）.Results UPLMS ISR rate was 14.8% （n=73, 15.7% after BMS, 14.5% for DES） after average of （3.89±2.01） years （range from 1 to 10.5 years） follow-up. Angiographic follow-up between 6-8 months was available in 85.3%. Of these,repeat percutaneous coronary intervention （PCI） was used in 62 （84.9%） patients, with medicine only in 9 （12.4%） and coronary artery bypass graft （CABG） in 2 （2.7%）. Most repeat PCI patients were with unstable angina （87.0%）, and had decreased left ventricular ejection fraction （（42.58±5.12）%）, fewer focal/ostial left circumflex branch （LCX） lesions, in relative to medicine only group. After （31.9±23.3） months, the MACE, Ml, TVR and cardiac death were 31.5%, 1.4%, 24.1% and 8.2%, respectively. Definite and possible stent thrombosis occurred in 1 （1.4%） patient.Conclusions Medical therapy for asymptomatic isolated ostial LCX was safe. Repeat PCI for UPLMS ISR was associated with acceptable early and short-term clinical outcome. Further study was needed to elucidate the role of CABG in treating UPLMS ISR.展开更多
Transition metal-catalyzed asymmetric hydrogenation(AH)of unprotected indoles has mainly been applied to alkyl substituted unprotected indoles.However,the challenging aryl substituted unprotected indoles with poor rea...Transition metal-catalyzed asymmetric hydrogenation(AH)of unprotected indoles has mainly been applied to alkyl substituted unprotected indoles.However,the challenging aryl substituted unprotected indoles with poor reactivity and enantioselectivity(≤42%ee)could not be hydrogenated well.In this work,a highly efficient Ir/bisphosphine-thiourea ligand ZhaoPhos catalytic system for the AH of challenging aryl substituted unprotected indoles has been successfully developed for the first time with high reactivity and excellent stereoselective control.Moreover,a series of 2-alkyl-substituted and 2,3-disubstituted unprotected indoles were also well tolerated in this catalytic system.A wide variety of chiral indoline derivatives were obtained in good to high yields with excellent stereoselectivities(75–99%yields,>20:1 dr,and 86–99%ee).The anion-binding activation strategy played an important role in accessing both high reactivity and excellent stereoselectivity,which was formed between the catalyst and unprotected indoles in situ-generating iminium ion with the assistance of Brønsted acid.A possible catalytic mechanism was proposed for this Ir-catalyzed AH according to density functional theory calculations and control experiment results.Readily available substrates,a broad range of substrate tolerance,an efficient chiral catalytic system,and a gram-scale protocol further demonstrated the potential practicality of this methodology.展开更多
In this article, a novel oligomerization behavior of unprotected monosaccharides was discovered in a one-pot reaction induced by phosphorus reagent at room temperature. The inherent characteristics of the oligomerizat...In this article, a novel oligomerization behavior of unprotected monosaccharides was discovered in a one-pot reaction induced by phosphorus reagent at room temperature. The inherent characteristics of the oligomerization reaction were dissected in detail by mass spectrometry based method combined with NMR technology. It was found that the main glycosidic bonding pattern is (1→6) linkage with 66% regioselectivity for each step. The ratio of α-(1→6) and β-(1→6) glycosidic bonds formed is around 1:1. The reactivity of 1-OH group from aldoses and the driving force from penta-coordinated phosphorus intermediates are the two critical factors for the oligomerization, according to the monitoring experiments by ESI-MS and NMR. Besides, the oligomerization reaction has good compatibility for various aldoses and could expand to O-glycosylated modification of peptides in vitro. The above results will provide a novel enlightenment to develop more convenient and higher-efficient methods for the synthesis of oligosaccharide library.展开更多
Background It is still controversial whether percutaneous coronary intervention with drug-eluting stent （DES） is safe and effective compared to coronary artery bypass graft surgery （CABG） for unprotected left main...Background It is still controversial whether percutaneous coronary intervention with drug-eluting stent （DES） is safe and effective compared to coronary artery bypass graft surgery （CABG） for unprotected left main coronary artery （ULMCA） disease at long-term follow up （≥3 years）. Methods Eligible studies were selected by searching PubMed, EMBASE, and Cochrane Library up to December 6, 2016. The primary endpoint was a composite of death, myocardial infarction （MI） or stroke during the longest follow-up. Death, cardiac death, MI, stroke and repeat revascularization were the secondary outcomes. Results Four randomized controlled trials and twelve adjusted observational studies involving 14,130 patients were included. DES was comparable to CABG regarding the occurrence of the primary endpoint （FIR = 0.94, 95% CI： 0.86-1.03）. Besides, DES was significantly associated with higher incidence of MI （HR = 1.56, 95% CI： 1.09-2.22） and repeat revascularization （HR = 3.09, 95% CI： 2.33-4.10） compared with CABG, while no difference was found between the two strategies regard as the rate of death, cardiac death and stroke. Furthermore, DES can reduce the risk of the composite endpoint of death, MI or stroke （HR = 0.80, 95% CI： 0.67-0.95） for ULMCA lesions with SYNTAX score ≤32. Conclusions Although with higher risk of repeat revascularization, PCI with DES appears to be as safe as CABG for ULMCA disease at long-term follow up. In addition, treatment with DES could be an alternative interventional strategy to CABG for ULMCA lesions with low to intermediate anatomic complexity.展开更多
Compared with high infection areas of the world, the total HIV infection rate in China is relatively low. Nonetheless, because of China’s vast territory and large population, the potential infection risk must be take...Compared with high infection areas of the world, the total HIV infection rate in China is relatively low. Nonetheless, because of China’s vast territory and large population, the potential infection risk must be taken seriously. In the next few years, needle sharing among injection drug users will remain the most common route of transmission for the HIV/ AIDS epidemic in China. Unprotected sex is gradually becoming a major route of transmission. China began to imple- ment HAART in 1999 according to international standards. Prior to 2003, there were only about 150 HIV/AIDS patients were treated with HAART in some clinical trials and about 100 HIV/AIDS patients were treated by private sources. Results of those treatments are the scientific basis for development of the therapeutic strategies in China. In March of 2003, the Chinese government initiated China CARES program. In November of 2003, the Chinese Ministry of Health announced a national policy of free ARV treatment to all HIV+ Chinese citizens who were in poverty and required ARV therapy. There are total of 19,456 HIV/AIDS patients received free ARV drugs to date in 159 regions and 441 towns. Current challenges are how to follow-up and evaluate those patients in the clinical settings. The longer the therapy is postponed, the more side effects and the higher probability of drug resistance are going to occur. It remains unclear, therefore, when HAART regimen should be started in the HIV/AIDS population in China.展开更多
In-situ study on eleven commercially important species viz; Adiantum capillus-veneris L, Bergenia ciliata (Haw) Sternb, Colchicum luteum Baker, Polygonum amplexicaule D.Den, Cuminum cyminum L, Dioscorea deltoidea Wall...In-situ study on eleven commercially important species viz; Adiantum capillus-veneris L, Bergenia ciliata (Haw) Sternb, Colchicum luteum Baker, Polygonum amplexicaule D.Den, Cuminum cyminum L, Dioscorea deltoidea Wall Kunth,L Morchella esculenta L, Paeonia emodi Wall ex H Kf, Podophyllum hexandrum (Royle) Chatt & Mukh, Valeriana wallichii DC and Viola serpens Wall ex Roxb was conducted in four locations viz; Malam (1 400 to 2 000?m),Bargin (1 700 to 2 300?m),Biakand (1 500 to 2 100?m) and Shinko (2 100 to 2 700?m).The data was recorded from both protected and unprotected sites of each site.Each site had 3 altitudinal sampling point.The density, herbage coverage and fresh biomass were determined in each locations for every species.All the investigated parameters generally showed an increase of 3 to 6 times over unprotected sites in each locations. Morchella esculenta,Dioscorea deltoidea,Colchicum luteum and Podophyllum hexandrum were absent in all unprotected sites while other species had low values in these sites.The investigated parameters of Colchicum luteum,Bergenia ciliata,Paeonioa emodi,Dioscorea deltoidea and Podophyllum hexandrum generally increased with the increasing elevation.Soil analysis,soil and air temperatures were recorded for each site.The air and soil temperature were slightly higher in open areas than in the protected site and showed decrease with increasing elevation.While the soil fertility was relatively high in protected sites as compared to unprotected area.The study shows that protection promotes the growth, distribution and occurrence of medicinal plants.It is possible with the participation of local communities to conserve these resources.展开更多
Background: Barrier contraception has the beauty of dual protection—against pregnancy and sexually transmitted infections. Following the persisting burden of unsafe abortion and human immunodeficiency virus (HIV), mu...Background: Barrier contraception has the beauty of dual protection—against pregnancy and sexually transmitted infections. Following the persisting burden of unsafe abortion and human immunodeficiency virus (HIV), much sensitization/campaign has been ongoing in the past few decades by government and non-governmental organisations (NGOs) in Nigeria against unprotected sexual intercourse. The youth are generally assumed to have high risk sexual behaviour, hence this study on Port Harcourt university undergraduates. Objectives: To determine the awareness and use of condom among University undergraduates in Port Harcourt. Methods: The study was a prospective descriptive cross-sectional study of 636 undergraduate students of the University of Port Harcourt and Rivers state University, South-south Nigeria. The multistage sampling technique was used to randomly select participants and data collected using a pretested structured self administered questionnaire. Data was analyzed using version 23.0 SPSS and reported in means, frequencies and percentages. Probability value was set at 5% (p χ2 = 200.602). Only 5.5% of the respondents in this study were willing to know their HIV status. Conclusion: There is a high level of condom awareness among Port Harcourt University undergraduates. Surprisingly, their practice of unprotected sexual intercourse is still high.展开更多
Serengeti is the largest ecosystem in Tanzania endowed with high level of biodiversity in protected and unprotected areas. Serengeti National Park is the only protected area in a matrix of unprotected areas characteri...Serengeti is the largest ecosystem in Tanzania endowed with high level of biodiversity in protected and unprotected areas. Serengeti National Park is the only protected area in a matrix of unprotected areas characterized with a wide range of human activities which threaten biodiversity conservation. It was assessed plant species composition, diversity, distribution and vegetation structure in both the protected and unprotected areas of the ecosystem. Two transects with twenty plots each were established in each vegetation type in which data was collected. A significantly higher species composition (262) and diversity (2.39 ± 0.03) was observed in unprotected areas than in the protected area (163 and 2.06 ± 0.04 respectively). The DCA ordination of the species data from the two management regimes formed four clusters based on similarity in plant species composition, where three clusters were from unprotected areas and one from protected area. The variations in plant species composition ranged from 35.69% to 65.92% for the first four DCA axes. There was no significant difference in stem density between protected and unprotected areas of the ecosystem. Although high density of trees at 10 - 14 cm DBH sizes was observed in both sides of the conservation management regimes, individuals with DBH above 65 cm existed in the protected area but were absent in unprotected areas. It can be concluded that the decrease of plant species diversity and density in unprotected area is because of habitat degradation associated with exploitation pressure, livestock grazing and other forms of disturbance related with anthropogenic activities. Because of high demand for plant resources, the local community needs to establish woodlots to cater for wood resource needs outside the protected areas of Serengeti. Also, pastoralists need to diversify livestock keeping systems compatible with limited grazing land in unprotected area of the Serengeti ecosystem.展开更多
<span style="font-family:Verdana;"><b><span style="font-family:Verdana;">Background: </span></b></span><span style="font-family:Verdana;"><spa...<span style="font-family:Verdana;"><b><span style="font-family:Verdana;">Background: </span></b></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">Young people, especially those in tertiary institutions are vulnerable to unplanned and unprotected sexual intercourse which predisposes them to unintended pregnancies and subsequently unsafe abortions. One of the key interventions for reduction of unwanted pregnancies and unsafe abortions is effective use of emergency contraceptives.</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">Objectives: </span></b></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">To assess the sexuality, perception, attitude towards and determinants of usage of emergency contraception among female undergraduates in Lagos, Nigeria. </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">Cross-sectional survey conducted in June 2016 among 805 female students of the Lagos State University. Data were collected through structured self-administered questionnaire by obtaining information </span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">on</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> demography, sexual and contraceptive history, perception, attitude towards and use of emergency contraceptives. Data obtained were analyzed using SPSS version 16. Chi-square and logistic regression models were applied to variables to test for significance that predict</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">s</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> the use of emergency contraceptives.</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">Results: </span></b></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">Of the 725 (90%) completed questionnaires,</span><b> </b><span style="font-family:Verdana;">334</span></span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">(46%) of the respondents were sexually active with 115</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">(34%) having previous history of pregnancy. Eighty-two percent of those pregnancies were unintended. Eighty-eight percent of those with unintended pregnancy had them terminated by induced abortions, 54% of which was carried out by untrained persons. Only 29% of those who had unprotected sexual intercourse used emergency contraceptives. Lack of knowledge and promotion of sexual promiscuity were identified as the main reasons for not using emergency contraceptives. Previous use of contraceptives, married status, increasing age and year of study were positive predictors for the use of emergency contraceptives while poor knowledge was a significant predictor of non-use. </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span style="font-family:Verdana;">There was poor knowledge and low utilization of emergency contraceptives among respondents. Information on contraceptives should be introduced in secondary schools and in general studies courses in tertiary institutions while parents and caregivers should discuss issues relating to sex and contraceptives with adolescents.</span></span></span></span>展开更多
Objectives: To describe and analyze risk factors associatedwith disuse of condoms during commercial sexual intercourseamong clients attending sauna and massage centers. Methods: Selected female sex workers from saunas...Objectives: To describe and analyze risk factors associatedwith disuse of condoms during commercial sexual intercourseamong clients attending sauna and massage centers. Methods: Selected female sex workers from saunas andbeauty parlors were trained as interviewers. They surveyedclients during provision of sexual services. Informationcollected included customers' demographics, knowledge ofSTDs, rationale for and history of condom use. Risk factorsfor condom usage were assessed though logistical modeling.Results: A total of 50 clients were interviewed. The rates ofcondom usage for last sexual intercourse with commercial andnon-commercial partners were 57% and 53% for clients ofsauna centers and 30% and 40% for clients of beauty parlors,respectively. The choice to use a condom was influenced byclients 60.8% of the time, sex workers 30.4%, and otherfactors 8.8%. The choice against using a condom was decidedupon by clients 69.7% of the time, sex workers 9.1%, andother factors 21.2%. Multivariate analysis showed thateducational level and perception of risk of infection werefactors for condom use. Clients with a high school educationhad a higher condom use rate than those with a middle schooleducation or less. Furthermore, clients who perceived risk ofdisease used condoms more frequently than those who did not.Conclusions: Clients played a significant role in decidingwhether or not to use a condom during commercial sex. Lackof perception of risk is a major factor for not using condoms.A program for promotion of prophylactics targeting bothcommercial sex workers and their clients is recommended.展开更多
基金supported by Natural Science Foun-dation of Hebei Province (D2006000701, C2007000247)Doctoral Fund of Hebei Normal University (L2008B11)
文摘A new breeding population of Mandarin Duck （Aix gaIericulata, Linnaeus） was first recorded in 2003 in Jiao- tanzhuang-Hehekou region of Pingshan county, Hebei Province, China. Recently, the gradually increasing population indicates that there are suitable breeding habitats （such as foraging habitats and nesting sites） for Mandarin Duck. However, these habitats are always close to human disturbances, which are the potential risk for their population. Therefore, it is urgent to put forward an applicable protection strategy, in order to strengthen the public awareness for this unprotected population.
基金support from the National Natural Science Foundation of China(No.22071187)the Natural Science Foundation of Jiangsu Province(No.BK20190213)the Natural Science Foundation of Hubei Province(Nos.2020CFA036,2021CFA069).
文摘Highly enantioselective Rh-catalyzed partial hydrogenation of unprotected simple 2-alkyl-5-aryl-disubstituted pyrroles has been successfully developed,generating a series of chiral 1-pyrroline derivatives generally with excellent results(95%-99%yields,91%-96%ee).Moreover,2,5-aryl-1H-pyrroles were hydrogenated well in high yields and good enantioselectivities.This efficient protocol features easily accessible substrates,wide substrate scope,well functional group compatibility,commercially available rhodium precursor and chiral ligand.It provides a versatile route to access chiral 1-pyrroline derivatives that are of great importance in organic synthesis and pharmaceutical chemistry.
基金supported by the Global Fund for AIDS program,China(Grant CSO-2012-YAN-39)
文摘The Yi are the largest and most disadvantaged ethnic minority population in southwestern China. This region contains over eight million Yi, with approximately 2.4 million living in the Liangshan Yi Autonomous Prefecture （Liangshan） in Sichuan Province. Liangshan is located along one of the main drug trafficking routes from the ＇Golden Triangle＇ to northwest and central China, making it one of the largest illicit drug production and distribution centers in China.
文摘Background: Percutaneous coronary intervention (PCI) has been increasingly employed to treat unprotected left main (ULM) stenosis, with hard endpoints similar to by-pass surgery, in patients selected by a Heart Team. Methods: From January 2008 to December 2011, 317 unselected and consecutive patients with de novo ULM stenosis underwent PCI with both bare metal (BMS) and drug-eluting (DES) stents. Major adverse cardiovascular events, target lesion (TLR) and vessel (TVR) revascularization were evaluated over a mean period of 590 ± 371 days. Results: Our population was characterized by a mean age 72 ± 10 years, high rate of acute coronary syndrome (ACS) (either with ST or non-ST elevation myocardial infarction, 15.5% and 35% respectively), severe comorbidity 16%, mean Euroscore 7 ± 3, mean Syntax Score 25 ± 9. In-hospital mortality was 6%. During the follow-up period, all-cause mortality was 16.7%, falling to 7% at the end of the follow-up, excluding patients presenting with ACS. TLR was observed and treated in 15% of patients. BMS utilization, age >75 years, ACS indication, Syntax Score >32 and associated peripheral artery disease were independent predictors of mortality at multivariate analysis. Conclusions: Stenting of ULM stenosis appears to be associated with a favorable mid-term outcome, even in an unselected population.
文摘Objective: to explore the effect of unprotected perineal delivery in delivery room nursing. Methods: 60 cases of puerpera in our hospital were randomly divided into two groups. Observation group without protection perineal midwifing nursing, control group routine nursing, compare its curative effect. Results: the observation group was significantly better than the control group in terms of perineal laceration, integrity, blood loss after delivery and satisfaction, P<0.05. Conclusion: unprotected perineal delivery is better.
文摘Objective: to analyze the effectiveness of this method of helping pregnant women during pregnancy and childbirth. We selected the testing method for the first delivery in our hospital from January 2020 to January 2021. A total of 60 cases were selected. Then all the infants were divided into two groups: observation group and control group with 30 cases each. The control group used traditional obstetric methods, while the observation group used unprotected obstetric methods. The frontal lobe ratio, pain degree, delivery time and bleeding degree of the two groups were compared. The comparative results show that the frontal lobe truncation rate of parturients in this group is significantly lower than that of the control group 14 (46.67%), and this group has maternal pain index (3.43%). In the case of maternal pain (5.73±1.34), duration of labor (643.15±49.3) and hemorrhage (341.7±16.27), the indicators of duration of labor (462.42±57.1) and hemorrhage (219.3±13.19) were also better than those of the control group. The difference of 16.27 between the two groups was statistically significant (P < 0.05). Conclusion: the use of untreated obstetric services for vaginal delivery of the first child in our hospital can effectively reduce the postpartum screening rate, shorten the delivery time of the parturient and relieve the pain of the mother, which is beneficial to the postpartum recovery of the mother and can be widely disseminated in clinical clinics.
文摘Objective:This paper mainly explores the application value of unprotected midwifery care for primipara natural childbirth.Methods:120 primiparas in our hospital from January 2017 to February 2019 were divided into routine group and Research Group,60 cases in each group.The routine group was given routine perineal protection midwifery,and the Research Group was given routine midwifery nursing.The nursing intervention effects of the two groups were compared statistically.Results:After statistics,VAS score and bleeding volume of perineal pain in the Research Group were lower than those in the conventional group,and the length of hospital stay in the Research Group was less than that in the conventional group,P<0.05;There was no significant difference in the time of the first stage of labor,the second stage of labor and the third stage of labor between the Research Group and the conventional group(P>0.05);The incidence of complications in the Research Group was lower than that in the conventional group(P<0.05).Conclusion:The application value of unprotected midwifery nursing intervention in primipara natural childbirth is significant.
文摘Objective: to explore the influence of unprotected perineal delivery in delivery room nursing. Methods: the selection time was from January 2020 to January 2021, and the subjects were parturients who delivered naturally through vagina. The above 100 parturients were divided into control group and experimental group by drawing lots, with 50 cases in each group. The control group was given the traditional delivery method, and the experimental group was given the unprotected perineal delivery method. The degree of perineal laceration, the time of the second stage of labor, the total amount of bleeding and the quality of life three months after delivery were compared between the two groups. Results: the degree of perineal laceration in the experimental group was lower than that in the control group (P < 0.05), and the data comparison was statistically significant. The duration of the second stage of labor and the amount of blood loss in the experimental group were less than those in the control group (P < 0.05), and the difference was statistically significant. 3months after delivery, two kinds of postpartum quality of life were investigated. The score of the experimental group was higher than that of the control group (P < 0.05), and the data difference is of comparative significance. Conclusion: unprotected perineal delivery method has less perineal damage to pregnant women, and is helpful to improve the quality of life of pregnant women after delivery. It is worthy of popularization and application.
文摘Objective: to study the value of unprotected midwifery in pregnant women's natural childbirth. Methods: according to our hospital in recent years admitted to the maternal as the research object of a total of 100 cases, according to the nursing model they were divided into two groups, each group of 50 cases, the control group using unprotected care model, the experimental group using traditional care model, observe the clinical experimental results of the two groups, the experimental results were analyzed. Results: the amount of vaginal bleeding, pain during delivery and hospital stay in the observation group were much lower than those in the control group. During the primary natural delivery of the parturient, the unprotected nursing can greatly shorten the delivery time, reduce the amount of vaginal bleeding, relieve the pain during delivery and reduce the complications after delivery. It has good clinical application and can be popularized. Conclusion: unprotected midwifery nursing in primipara's natural childbirth can effectively reduce the delivery time, reduce the amount of vaginal bleeding, and also can relieve the pain symptoms of childbirth, thus reducing postpartum complications.
文摘Background： There are limited data on longer-term outcomes （〉5 years） for patients with unprotected left main coronary artery （ULMCA） disease who underwent percutaneous coronary intervention （PCI） in the drug-eluting stents （DES） era. This study aimed at comparing the long-term （〉5 years） outcomes of patients with ULMCA disease underwent PCI with DES and coronary artery bypass grafting （CABG） and the predictors of adverse events. Methods： All consecutive patients with ULMCA disease treated with DES implantation versus CABG in our center, between January 2003 and July 2009, were screened for analyzing. A propensity score analysis was carried out to adjust for potential confounding between the two groups. Results： Nine hundred and twenty-two patients with ULMCA disease were enrolled for the analyses （DES = 465 vs. CABG = 457）. During the median follow-up of 7.1 years （interquartile range 5.3-8.2 years）, no difference was found between PCI and CABG in the occurrence of death （P = 0.282） and the composite endpoint of cardiac death, myocardial infarction （MI） and stroke （P = 0.294）. Rates of major adverse cardiac and cerebrovascular events were significantly higher in the PCI group （P = 0.014） in large part because of the significantly higher rate of repeat revascularization （P 〈 0.001）. PC/was correlated with the lower occurrence of stroke （P = 0.004）. Multivariate analysis showed ejection fraction （EF） （P = 0.012）, creatinine （P = 0.016）, and prior stroke （P = 0.03 l） were independent predictors of the composite endpoint of cardiac death, MI, and stroke in the DES group, while age （P = 0.026） and EF （P = 0.002） were independent predictors in the CABG group. Conclusions： During a median follow-up of 7.1 years, there was no difference in the rate of death between PCI with DES implantation and CABG in ULMCA lesions in the patient cohort. CABG group was observed to have significantly lower rates of repeat revascularization but higher stroke rates compared with PCI. EF, creatinine, and prior stroke were independent predictors of the composite endpoint of cardiac death, MI, and stroke in the DES group, while age and EF were independent predictors in the CABG group.
文摘Background Implantation of either bare metal stent （BMS） or drug-eluting stent （DES） has been used in every day practice for patients with unprotected left main stenosis （UPLMS）. There are still a lack of data regading the subsequent results of UPLMS in-stent restenosis （ISR）. The present study aimed at determing the clinical outcome of UPLMS ISR patients after implantation of either BMS or DES.Methods Patients with UPLMS ISR after stenting were included. The primary endpoint was the cumulative major adverse cardiac events （MACE）, including cardiac death, myocardial infarction （Ml）, and target vessel revascularization （TVR）.Results UPLMS ISR rate was 14.8% （n=73, 15.7% after BMS, 14.5% for DES） after average of （3.89±2.01） years （range from 1 to 10.5 years） follow-up. Angiographic follow-up between 6-8 months was available in 85.3%. Of these,repeat percutaneous coronary intervention （PCI） was used in 62 （84.9%） patients, with medicine only in 9 （12.4%） and coronary artery bypass graft （CABG） in 2 （2.7%）. Most repeat PCI patients were with unstable angina （87.0%）, and had decreased left ventricular ejection fraction （（42.58±5.12）%）, fewer focal/ostial left circumflex branch （LCX） lesions, in relative to medicine only group. After （31.9±23.3） months, the MACE, Ml, TVR and cardiac death were 31.5%, 1.4%, 24.1% and 8.2%, respectively. Definite and possible stent thrombosis occurred in 1 （1.4%） patient.Conclusions Medical therapy for asymptomatic isolated ostial LCX was safe. Repeat PCI for UPLMS ISR was associated with acceptable early and short-term clinical outcome. Further study was needed to elucidate the role of CABG in treating UPLMS ISR.
基金We are grateful for financial support from the National Natural Science Foundation of China(grant no.22071187)the Natural Science Foundation of Jiangsu Province(grant no.BK20190213)+3 种基金the Shenzhen Nobel Prize Scientists Laboratory Project(grant no.C17783101)the Guangdong Provincial Key Laboratory of Catalysis(grant no.2020B121201002)the Natural Science Foundation of Hubei Province(grant nos.2020CFA036 and 2021CFA069)the Scientific Research Project of Education Department of Hubei Province(grant no.B2020057).We are grateful to the High Performance Computing Center and the CHEM high performance supercomputer cluster(CHEM HPC)of the Southern University of Science and Technology.
文摘Transition metal-catalyzed asymmetric hydrogenation(AH)of unprotected indoles has mainly been applied to alkyl substituted unprotected indoles.However,the challenging aryl substituted unprotected indoles with poor reactivity and enantioselectivity(≤42%ee)could not be hydrogenated well.In this work,a highly efficient Ir/bisphosphine-thiourea ligand ZhaoPhos catalytic system for the AH of challenging aryl substituted unprotected indoles has been successfully developed for the first time with high reactivity and excellent stereoselective control.Moreover,a series of 2-alkyl-substituted and 2,3-disubstituted unprotected indoles were also well tolerated in this catalytic system.A wide variety of chiral indoline derivatives were obtained in good to high yields with excellent stereoselectivities(75–99%yields,>20:1 dr,and 86–99%ee).The anion-binding activation strategy played an important role in accessing both high reactivity and excellent stereoselectivity,which was formed between the catalyst and unprotected indoles in situ-generating iminium ion with the assistance of Brønsted acid.A possible catalytic mechanism was proposed for this Ir-catalyzed AH according to density functional theory calculations and control experiment results.Readily available substrates,a broad range of substrate tolerance,an efficient chiral catalytic system,and a gram-scale protocol further demonstrated the potential practicality of this methodology.
基金supported by the National Natural Science Foundation of China (21232005)the Natural Science Foundation of Fujian Province of China (2017J01024)the Fundamental Research Funds for the Central Universities (20720150049)
文摘In this article, a novel oligomerization behavior of unprotected monosaccharides was discovered in a one-pot reaction induced by phosphorus reagent at room temperature. The inherent characteristics of the oligomerization reaction were dissected in detail by mass spectrometry based method combined with NMR technology. It was found that the main glycosidic bonding pattern is (1→6) linkage with 66% regioselectivity for each step. The ratio of α-(1→6) and β-(1→6) glycosidic bonds formed is around 1:1. The reactivity of 1-OH group from aldoses and the driving force from penta-coordinated phosphorus intermediates are the two critical factors for the oligomerization, according to the monitoring experiments by ESI-MS and NMR. Besides, the oligomerization reaction has good compatibility for various aldoses and could expand to O-glycosylated modification of peptides in vitro. The above results will provide a novel enlightenment to develop more convenient and higher-efficient methods for the synthesis of oligosaccharide library.
文摘Background It is still controversial whether percutaneous coronary intervention with drug-eluting stent （DES） is safe and effective compared to coronary artery bypass graft surgery （CABG） for unprotected left main coronary artery （ULMCA） disease at long-term follow up （≥3 years）. Methods Eligible studies were selected by searching PubMed, EMBASE, and Cochrane Library up to December 6, 2016. The primary endpoint was a composite of death, myocardial infarction （MI） or stroke during the longest follow-up. Death, cardiac death, MI, stroke and repeat revascularization were the secondary outcomes. Results Four randomized controlled trials and twelve adjusted observational studies involving 14,130 patients were included. DES was comparable to CABG regarding the occurrence of the primary endpoint （FIR = 0.94, 95% CI： 0.86-1.03）. Besides, DES was significantly associated with higher incidence of MI （HR = 1.56, 95% CI： 1.09-2.22） and repeat revascularization （HR = 3.09, 95% CI： 2.33-4.10） compared with CABG, while no difference was found between the two strategies regard as the rate of death, cardiac death and stroke. Furthermore, DES can reduce the risk of the composite endpoint of death, MI or stroke （HR = 0.80, 95% CI： 0.67-0.95） for ULMCA lesions with SYNTAX score ≤32. Conclusions Although with higher risk of repeat revascularization, PCI with DES appears to be as safe as CABG for ULMCA disease at long-term follow up. In addition, treatment with DES could be an alternative interventional strategy to CABG for ULMCA lesions with low to intermediate anatomic complexity.
文摘Compared with high infection areas of the world, the total HIV infection rate in China is relatively low. Nonetheless, because of China’s vast territory and large population, the potential infection risk must be taken seriously. In the next few years, needle sharing among injection drug users will remain the most common route of transmission for the HIV/ AIDS epidemic in China. Unprotected sex is gradually becoming a major route of transmission. China began to imple- ment HAART in 1999 according to international standards. Prior to 2003, there were only about 150 HIV/AIDS patients were treated with HAART in some clinical trials and about 100 HIV/AIDS patients were treated by private sources. Results of those treatments are the scientific basis for development of the therapeutic strategies in China. In March of 2003, the Chinese government initiated China CARES program. In November of 2003, the Chinese Ministry of Health announced a national policy of free ARV treatment to all HIV+ Chinese citizens who were in poverty and required ARV therapy. There are total of 19,456 HIV/AIDS patients received free ARV drugs to date in 159 regions and 441 towns. Current challenges are how to follow-up and evaluate those patients in the clinical settings. The longer the therapy is postponed, the more side effects and the higher probability of drug resistance are going to occur. It remains unclear, therefore, when HAART regimen should be started in the HIV/AIDS population in China.
文摘In-situ study on eleven commercially important species viz; Adiantum capillus-veneris L, Bergenia ciliata (Haw) Sternb, Colchicum luteum Baker, Polygonum amplexicaule D.Den, Cuminum cyminum L, Dioscorea deltoidea Wall Kunth,L Morchella esculenta L, Paeonia emodi Wall ex H Kf, Podophyllum hexandrum (Royle) Chatt & Mukh, Valeriana wallichii DC and Viola serpens Wall ex Roxb was conducted in four locations viz; Malam (1 400 to 2 000?m),Bargin (1 700 to 2 300?m),Biakand (1 500 to 2 100?m) and Shinko (2 100 to 2 700?m).The data was recorded from both protected and unprotected sites of each site.Each site had 3 altitudinal sampling point.The density, herbage coverage and fresh biomass were determined in each locations for every species.All the investigated parameters generally showed an increase of 3 to 6 times over unprotected sites in each locations. Morchella esculenta,Dioscorea deltoidea,Colchicum luteum and Podophyllum hexandrum were absent in all unprotected sites while other species had low values in these sites.The investigated parameters of Colchicum luteum,Bergenia ciliata,Paeonioa emodi,Dioscorea deltoidea and Podophyllum hexandrum generally increased with the increasing elevation.Soil analysis,soil and air temperatures were recorded for each site.The air and soil temperature were slightly higher in open areas than in the protected site and showed decrease with increasing elevation.While the soil fertility was relatively high in protected sites as compared to unprotected area.The study shows that protection promotes the growth, distribution and occurrence of medicinal plants.It is possible with the participation of local communities to conserve these resources.
文摘Background: Barrier contraception has the beauty of dual protection—against pregnancy and sexually transmitted infections. Following the persisting burden of unsafe abortion and human immunodeficiency virus (HIV), much sensitization/campaign has been ongoing in the past few decades by government and non-governmental organisations (NGOs) in Nigeria against unprotected sexual intercourse. The youth are generally assumed to have high risk sexual behaviour, hence this study on Port Harcourt university undergraduates. Objectives: To determine the awareness and use of condom among University undergraduates in Port Harcourt. Methods: The study was a prospective descriptive cross-sectional study of 636 undergraduate students of the University of Port Harcourt and Rivers state University, South-south Nigeria. The multistage sampling technique was used to randomly select participants and data collected using a pretested structured self administered questionnaire. Data was analyzed using version 23.0 SPSS and reported in means, frequencies and percentages. Probability value was set at 5% (p χ2 = 200.602). Only 5.5% of the respondents in this study were willing to know their HIV status. Conclusion: There is a high level of condom awareness among Port Harcourt University undergraduates. Surprisingly, their practice of unprotected sexual intercourse is still high.
文摘Serengeti is the largest ecosystem in Tanzania endowed with high level of biodiversity in protected and unprotected areas. Serengeti National Park is the only protected area in a matrix of unprotected areas characterized with a wide range of human activities which threaten biodiversity conservation. It was assessed plant species composition, diversity, distribution and vegetation structure in both the protected and unprotected areas of the ecosystem. Two transects with twenty plots each were established in each vegetation type in which data was collected. A significantly higher species composition (262) and diversity (2.39 ± 0.03) was observed in unprotected areas than in the protected area (163 and 2.06 ± 0.04 respectively). The DCA ordination of the species data from the two management regimes formed four clusters based on similarity in plant species composition, where three clusters were from unprotected areas and one from protected area. The variations in plant species composition ranged from 35.69% to 65.92% for the first four DCA axes. There was no significant difference in stem density between protected and unprotected areas of the ecosystem. Although high density of trees at 10 - 14 cm DBH sizes was observed in both sides of the conservation management regimes, individuals with DBH above 65 cm existed in the protected area but were absent in unprotected areas. It can be concluded that the decrease of plant species diversity and density in unprotected area is because of habitat degradation associated with exploitation pressure, livestock grazing and other forms of disturbance related with anthropogenic activities. Because of high demand for plant resources, the local community needs to establish woodlots to cater for wood resource needs outside the protected areas of Serengeti. Also, pastoralists need to diversify livestock keeping systems compatible with limited grazing land in unprotected area of the Serengeti ecosystem.
文摘<span style="font-family:Verdana;"><b><span style="font-family:Verdana;">Background: </span></b></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">Young people, especially those in tertiary institutions are vulnerable to unplanned and unprotected sexual intercourse which predisposes them to unintended pregnancies and subsequently unsafe abortions. One of the key interventions for reduction of unwanted pregnancies and unsafe abortions is effective use of emergency contraceptives.</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">Objectives: </span></b></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">To assess the sexuality, perception, attitude towards and determinants of usage of emergency contraception among female undergraduates in Lagos, Nigeria. </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">Cross-sectional survey conducted in June 2016 among 805 female students of the Lagos State University. Data were collected through structured self-administered questionnaire by obtaining information </span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">on</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> demography, sexual and contraceptive history, perception, attitude towards and use of emergency contraceptives. Data obtained were analyzed using SPSS version 16. Chi-square and logistic regression models were applied to variables to test for significance that predict</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">s</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> the use of emergency contraceptives.</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">Results: </span></b></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">Of the 725 (90%) completed questionnaires,</span><b> </b><span style="font-family:Verdana;">334</span></span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">(46%) of the respondents were sexually active with 115</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">(34%) having previous history of pregnancy. Eighty-two percent of those pregnancies were unintended. Eighty-eight percent of those with unintended pregnancy had them terminated by induced abortions, 54% of which was carried out by untrained persons. Only 29% of those who had unprotected sexual intercourse used emergency contraceptives. Lack of knowledge and promotion of sexual promiscuity were identified as the main reasons for not using emergency contraceptives. Previous use of contraceptives, married status, increasing age and year of study were positive predictors for the use of emergency contraceptives while poor knowledge was a significant predictor of non-use. </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span style="font-family:Verdana;">There was poor knowledge and low utilization of emergency contraceptives among respondents. Information on contraceptives should be introduced in secondary schools and in general studies courses in tertiary institutions while parents and caregivers should discuss issues relating to sex and contraceptives with adolescents.</span></span></span></span>
基金This study was supported by China National Center for AIDS Prevention and Control and Peking Union School of Public Health.
文摘Objectives: To describe and analyze risk factors associatedwith disuse of condoms during commercial sexual intercourseamong clients attending sauna and massage centers. Methods: Selected female sex workers from saunas andbeauty parlors were trained as interviewers. They surveyedclients during provision of sexual services. Informationcollected included customers' demographics, knowledge ofSTDs, rationale for and history of condom use. Risk factorsfor condom usage were assessed though logistical modeling.Results: A total of 50 clients were interviewed. The rates ofcondom usage for last sexual intercourse with commercial andnon-commercial partners were 57% and 53% for clients ofsauna centers and 30% and 40% for clients of beauty parlors,respectively. The choice to use a condom was influenced byclients 60.8% of the time, sex workers 30.4%, and otherfactors 8.8%. The choice against using a condom was decidedupon by clients 69.7% of the time, sex workers 9.1%, andother factors 21.2%. Multivariate analysis showed thateducational level and perception of risk of infection werefactors for condom use. Clients with a high school educationhad a higher condom use rate than those with a middle schooleducation or less. Furthermore, clients who perceived risk ofdisease used condoms more frequently than those who did not.Conclusions: Clients played a significant role in decidingwhether or not to use a condom during commercial sex. Lackof perception of risk is a major factor for not using condoms.A program for promotion of prophylactics targeting bothcommercial sex workers and their clients is recommended.
