为更好地描述砂土力学行为的围压相关性,首先,分析总结了砂土基本力学特性随围压的变化规律:随围压的降低,砂土基本力学性质表现出更为强烈的围压依赖性,临界状态应力比由常量变为随围压敏感的变量,剪胀也由随围压平缓变化转变为急剧增...为更好地描述砂土力学行为的围压相关性,首先,分析总结了砂土基本力学特性随围压的变化规律:随围压的降低,砂土基本力学性质表现出更为强烈的围压依赖性,临界状态应力比由常量变为随围压敏感的变量,剪胀也由随围压平缓变化转变为急剧增加。随后,在黏土和砂土的统一硬化模型(unified hardening model for cloy and sand,CSUH模型)的理论框架下,引入了咬合应力参数以描述临界状态的强度特征;提出了非耦合塑性体应变的概念,从微观层面解释了低围压下强剪胀的机制,在分析围压对压剪耦合影响规律的基础上,构造了非耦合塑性体应变的表达式,继而建立了一个可细化描述围压效应的砂土统一硬化(unified hardening,UH)模型。相较于CSUH模型,考虑围压效应的UH模型仅增加了两个参数,且参数易于确定。最后,通过与试验数据、CSUH模型预测结果对比,验证了所建立模型的合理性及适用性。展开更多
Chlorfenapyr poisoning is associated with high mortality due to the absence of evidence-based treatment strategies or specific antidotes.[1,2]Chlorfenapyr is a novel N-substituted halogenated pyrrole pro-insecticide.T...Chlorfenapyr poisoning is associated with high mortality due to the absence of evidence-based treatment strategies or specific antidotes.[1,2]Chlorfenapyr is a novel N-substituted halogenated pyrrole pro-insecticide.The active metabolite of tralopyril(a metabolite of chlorfenapyr)can uncouple oxidative phosphorylation and impair adenosine triphosphate(ATP)production.[3]Blood purification techniques,including hemoperfusion(HP),may facilitate tralopyril clearance.[4,5]Here,we present a case of severe chlorfenapyr poisoning that was treated with intensive HP.H owever,during follow-up,we unexpectedly found a ventricular aneurysm in the left ventricle that was not fully explained by coronary artery lesions.展开更多
文摘为更好地描述砂土力学行为的围压相关性,首先,分析总结了砂土基本力学特性随围压的变化规律:随围压的降低,砂土基本力学性质表现出更为强烈的围压依赖性,临界状态应力比由常量变为随围压敏感的变量,剪胀也由随围压平缓变化转变为急剧增加。随后,在黏土和砂土的统一硬化模型(unified hardening model for cloy and sand,CSUH模型)的理论框架下,引入了咬合应力参数以描述临界状态的强度特征;提出了非耦合塑性体应变的概念,从微观层面解释了低围压下强剪胀的机制,在分析围压对压剪耦合影响规律的基础上,构造了非耦合塑性体应变的表达式,继而建立了一个可细化描述围压效应的砂土统一硬化(unified hardening,UH)模型。相较于CSUH模型,考虑围压效应的UH模型仅增加了两个参数,且参数易于确定。最后,通过与试验数据、CSUH模型预测结果对比,验证了所建立模型的合理性及适用性。
基金supported by the National Key Research and Development Program of China(2023YFC3603100 and 2023YFC3603105)"Leading Goose"R&D Program of Zhejiang(2022C03076-4).
文摘Chlorfenapyr poisoning is associated with high mortality due to the absence of evidence-based treatment strategies or specific antidotes.[1,2]Chlorfenapyr is a novel N-substituted halogenated pyrrole pro-insecticide.The active metabolite of tralopyril(a metabolite of chlorfenapyr)can uncouple oxidative phosphorylation and impair adenosine triphosphate(ATP)production.[3]Blood purification techniques,including hemoperfusion(HP),may facilitate tralopyril clearance.[4,5]Here,we present a case of severe chlorfenapyr poisoning that was treated with intensive HP.H owever,during follow-up,we unexpectedly found a ventricular aneurysm in the left ventricle that was not fully explained by coronary artery lesions.
