In order to explore the effect of electroacupuncture on rats with acute spinal injury,we established animal model of the spinal injury.Total proteins were extracted from spinal cord of normal rats,acute spinal injury ...In order to explore the effect of electroacupuncture on rats with acute spinal injury,we established animal model of the spinal injury.Total proteins were extracted from spinal cord of normal rats,acute spinal injury rats and acute spinal injury rat treated by electroacupuncture,and separated by 2-DE.10 differential expressed proteins were identified by the MALDI-TOF-TOF-MS with high mass accuracy,high mascot scores and high reliability.展开更多
19世纪的牙医Charles Stent怎会想到他因为发明了用于制造牙膜的热弹性材料而引发了支架的最初设想,使其名字在100年后的消化领域被如此频繁的提及.消化系疾病的支架治疗是继血管介入术后另一个发展异常迅速的领域.20世纪80年代,人们已...19世纪的牙医Charles Stent怎会想到他因为发明了用于制造牙膜的热弹性材料而引发了支架的最初设想,使其名字在100年后的消化领域被如此频繁的提及.消化系疾病的支架治疗是继血管介入术后另一个发展异常迅速的领域.20世纪80年代,人们已开始用塑料支架治疗各种恶性食管狭窄,但因操作过程复杂、并发症发生率高、疗效差等原因使其应用范围大受限制.1990年德国学者Domschke et al[1]最先报道使用Wallstent金属支架治疗恶性食管狭窄以来,整个支架治疗的概念、方法进入了新的阶段.近10年来,随着各种不同材质、构造、形状的金属支架及推送器的问世和技术改进,支架治疗的整体效果、各种并发症的发生率及处理手段均有了相应的变化.回顾金属支架的演进、改良和发展历史,全面了解各类支架的物理性能、特点和临床应用情况,对实际操作工作中支架的选择、支架效能的发挥和降低并发症率都是大有裨益的.展开更多
Objectives: To present the complications of Ultraflex Self-Expandable Metallic Stents (SEMSs) applied in patients with benign tracheobronchial diseases. Methods: Eighty patients received 124 SEMSs were retrospectively...Objectives: To present the complications of Ultraflex Self-Expandable Metallic Stents (SEMSs) applied in patients with benign tracheobronchial diseases. Methods: Eighty patients received 124 SEMSs were retrospectively reviewed in a tertiary hospital. Results: The baseline characteristics of patients received SEMS implantation including age (mean + standard deviation: 62.5 + 14.8 years), gender (male, 60.5%), smoking (46.8%), forced expiratory volume in first one second (FEV1) (mean + standard deviation, 0.92 +0.41 L/s), follow-up days after SEMS implantation (median (interquartile range);457 (131 - 897)) and covered SEMS (33.9%) were listed. Symptoms improved after SEMS implantation among 95 patients (76.6%). Time to complications developed was 236 (median;interquartile range, 59 - 672) days. The overall complication rate was 41.9% after SEMS implantation. The complications included SEMS migration (6.5%), granuloma (19.3%) and SEMS fracture (16.1%). Successful management rates of SEMS migration, granuloma and SEMS fracture were up to 100%, 83.3%, and 85% respectively. Conclusions: Patients received SEMS implantation due to benign conditions had poor lung function and were old. The complication rate in patients with benign conditions was high after longer follow-up period, however, successful management achieved in most patients with complications.展开更多
The development of large-area high-performance flexible photoelectronic synaptic devices has become a hot topic in the field of neuromorphic computing and artificial vision systems.In this work,we have successfully pr...The development of large-area high-performance flexible photoelectronic synaptic devices has become a hot topic in the field of neuromorphic computing and artificial vision systems.In this work,we have successfully prepared a large-area,ultra-flexible semiconducting single-walled carbon nanotubes(sc-SWCNTs)photoelectronic synaptic thin-film transistors(TFTs)array(33×34)using solution-processable AlO_(x)thin film as the dielectrics by roll-to-roll gravure printing.Our photoelectronic synaptic TFTs exhibit excellent electrical properties with high switching ratio(≥10^(5)),low subthreshold swing(73 mV·dec^(−1)),excellent photoresponse properties over a wide wavelength range(from 270 to 650 nm),sustained photoconductivity effect(only 26.7%drop after removing light source for 36,000 s)and remarkable mechanical reliability and flexibility(maintaining excellent electrical properties after bending more than 15,000 cycles with a bending radius of 5 mm).In addition,concepts such as multimodal optoelectronic synaptic plasticity,optical writing speed perception simulation,and human eye self-recovery model have been successfully demonstrated using printed flexible sc-SWCNTs photoelectronic neuromorphic TFTs arrays.More importantly,we systematically investigated the response characteristics of these devices under deep ultraviolet light stimulation and,for the first time,successfully simulated bio-inspired visual perception self-recovery including the dynamic transition of the visual system from clarity to blurriness and their self-recovery over time.This work indicates that our photoelectronic neuromorphic TFT devices have great practical potential in human-computer interaction,environment perception,and visual simulation.展开更多
Driven by innovations in the form factor of organic light-emitting diode(OLED)displays,the application scope of OLED technology now encompasses the biomedical field,in addition to its existing application domains of m...Driven by innovations in the form factor of organic light-emitting diode(OLED)displays,the application scope of OLED technology now encompasses the biomedical field,in addition to its existing application domains of mobile phones,televisions,and lighting.This paper introduces an ultrathin,ultraflexible,and high-power bio-OLED patch with perfect waterproofing and an elongation of 2.04%through material and structural design.Furthermore,the OLED patch with a parallel-stacked OLED delivers a high output of 100 mW/cm^(2),achieves a 40%power density improvement compared to glass-based OLEDs using optimized encapsulation,and is suitable for photodynamic therapy owing to its lifetime of 183 h at an intensity of 35 mW/cm^(2).Since OLED patches are required for long-term stable operation in various biomedical applications,we developed an OLED patch with an outcoupling structure using a simple method.The improved OLED patch achieved a 35%increase in light extraction compared to the original OLED patch.展开更多
文摘In order to explore the effect of electroacupuncture on rats with acute spinal injury,we established animal model of the spinal injury.Total proteins were extracted from spinal cord of normal rats,acute spinal injury rats and acute spinal injury rat treated by electroacupuncture,and separated by 2-DE.10 differential expressed proteins were identified by the MALDI-TOF-TOF-MS with high mass accuracy,high mascot scores and high reliability.
文摘19世纪的牙医Charles Stent怎会想到他因为发明了用于制造牙膜的热弹性材料而引发了支架的最初设想,使其名字在100年后的消化领域被如此频繁的提及.消化系疾病的支架治疗是继血管介入术后另一个发展异常迅速的领域.20世纪80年代,人们已开始用塑料支架治疗各种恶性食管狭窄,但因操作过程复杂、并发症发生率高、疗效差等原因使其应用范围大受限制.1990年德国学者Domschke et al[1]最先报道使用Wallstent金属支架治疗恶性食管狭窄以来,整个支架治疗的概念、方法进入了新的阶段.近10年来,随着各种不同材质、构造、形状的金属支架及推送器的问世和技术改进,支架治疗的整体效果、各种并发症的发生率及处理手段均有了相应的变化.回顾金属支架的演进、改良和发展历史,全面了解各类支架的物理性能、特点和临床应用情况,对实际操作工作中支架的选择、支架效能的发挥和降低并发症率都是大有裨益的.
文摘Objectives: To present the complications of Ultraflex Self-Expandable Metallic Stents (SEMSs) applied in patients with benign tracheobronchial diseases. Methods: Eighty patients received 124 SEMSs were retrospectively reviewed in a tertiary hospital. Results: The baseline characteristics of patients received SEMS implantation including age (mean + standard deviation: 62.5 + 14.8 years), gender (male, 60.5%), smoking (46.8%), forced expiratory volume in first one second (FEV1) (mean + standard deviation, 0.92 +0.41 L/s), follow-up days after SEMS implantation (median (interquartile range);457 (131 - 897)) and covered SEMS (33.9%) were listed. Symptoms improved after SEMS implantation among 95 patients (76.6%). Time to complications developed was 236 (median;interquartile range, 59 - 672) days. The overall complication rate was 41.9% after SEMS implantation. The complications included SEMS migration (6.5%), granuloma (19.3%) and SEMS fracture (16.1%). Successful management rates of SEMS migration, granuloma and SEMS fracture were up to 100%, 83.3%, and 85% respectively. Conclusions: Patients received SEMS implantation due to benign conditions had poor lung function and were old. The complication rate in patients with benign conditions was high after longer follow-up period, however, successful management achieved in most patients with complications.
基金supported by the National Key Research and Development Program of China(No.2020YFA0714700)the National Natural Science Foundation of China(Nos.62274174 and 52173192)+2 种基金Basic Research Program of Jiangsu(No.BK20232009)a fellowship from the China Postdoctoral Science Foundation(NO.2023M742559)the Cooperation Project of Vacuum Interconnect Research Facility(NANO-X)of Suzhou Institute of Nano-Tech and Nano-Bionics,Chinese Academy of Sciences(No.F2208).
文摘The development of large-area high-performance flexible photoelectronic synaptic devices has become a hot topic in the field of neuromorphic computing and artificial vision systems.In this work,we have successfully prepared a large-area,ultra-flexible semiconducting single-walled carbon nanotubes(sc-SWCNTs)photoelectronic synaptic thin-film transistors(TFTs)array(33×34)using solution-processable AlO_(x)thin film as the dielectrics by roll-to-roll gravure printing.Our photoelectronic synaptic TFTs exhibit excellent electrical properties with high switching ratio(≥10^(5)),low subthreshold swing(73 mV·dec^(−1)),excellent photoresponse properties over a wide wavelength range(from 270 to 650 nm),sustained photoconductivity effect(only 26.7%drop after removing light source for 36,000 s)and remarkable mechanical reliability and flexibility(maintaining excellent electrical properties after bending more than 15,000 cycles with a bending radius of 5 mm).In addition,concepts such as multimodal optoelectronic synaptic plasticity,optical writing speed perception simulation,and human eye self-recovery model have been successfully demonstrated using printed flexible sc-SWCNTs photoelectronic neuromorphic TFTs arrays.More importantly,we systematically investigated the response characteristics of these devices under deep ultraviolet light stimulation and,for the first time,successfully simulated bio-inspired visual perception self-recovery including the dynamic transition of the visual system from clarity to blurriness and their self-recovery over time.This work indicates that our photoelectronic neuromorphic TFT devices have great practical potential in human-computer interaction,environment perception,and visual simulation.
基金supported by the Technology Innovation Program(20018379Development of high-reliability light-emitting fiber-based woven wearable displays)funded By the Ministry of Trade,Industry&Energy(MOTIE,Korea)supported by the Technology developmentProgram(RS-2024-00469790)funded by the Ministry of SMEs and Startups(MSS,Korea).
文摘Driven by innovations in the form factor of organic light-emitting diode(OLED)displays,the application scope of OLED technology now encompasses the biomedical field,in addition to its existing application domains of mobile phones,televisions,and lighting.This paper introduces an ultrathin,ultraflexible,and high-power bio-OLED patch with perfect waterproofing and an elongation of 2.04%through material and structural design.Furthermore,the OLED patch with a parallel-stacked OLED delivers a high output of 100 mW/cm^(2),achieves a 40%power density improvement compared to glass-based OLEDs using optimized encapsulation,and is suitable for photodynamic therapy owing to its lifetime of 183 h at an intensity of 35 mW/cm^(2).Since OLED patches are required for long-term stable operation in various biomedical applications,we developed an OLED patch with an outcoupling structure using a simple method.The improved OLED patch achieved a 35%increase in light extraction compared to the original OLED patch.
