This paper deals with the boundedness and compactness of the compositionintegral type operators T g, from F (p, q, s) spaces to(little) Bloch-type spaces in the unit ball of C n , where Tg,φf(z) =∫01fφ(tz)Rg(tz)(dt...This paper deals with the boundedness and compactness of the compositionintegral type operators T g, from F (p, q, s) spaces to(little) Bloch-type spaces in the unit ball of C n , where Tg,φf(z) =∫01fφ(tz)Rg(tz)(dt)/t , z ∈ B, g ∈ H(B) and φ∈H(B, B).展开更多
Product storage policy, single picking volume and picking routing are the three factors of vital importance that affect the efficiency of a crane to pick goods in automated storage and retrieval systems(AS/RS). Compar...Product storage policy, single picking volume and picking routing are the three factors of vital importance that affect the efficiency of a crane to pick goods in automated storage and retrieval systems(AS/RS). Comparative experiments on picking efficiency were conducted targeting picking operation with order of 1 to 20. Based on dedicated and random storage policies, 4 picking methods of patching-based, S-type, return-type and optimized-type routes were used and compared in the experiments. The results show that either the dedicated policy or the random policy was applied, crane worked most efficiently with optimizedtype route, followed by S-type path, patching-based path, and return-type path. When the number of orders in a single picking is larger(more than 5), the random storage policy is preferable to the dedicated policy.展开更多
This paper deals with the boundedness and compactness of the weighted composition operators from the F（p, q, s） spaces, including Hardy space, Bergman space, Qp space, BMOA space, Besov space and α-Bloch space, to ...This paper deals with the boundedness and compactness of the weighted composition operators from the F（p, q, s） spaces, including Hardy space, Bergman space, Qp space, BMOA space, Besov space and α-Bloch space, to Bers-type spaces Hv^∞（ or little Bers-type spaces Hv,o∞ ）, where v is normal.展开更多
The effects of Sonic hedgehog(Shh) signaling pathway activation on S-type neuroblastoma(NB) cell lines and its role in NB tumorigenesis were investigated.Immunohistochemistry was used to detect the expression of Shh p...The effects of Sonic hedgehog(Shh) signaling pathway activation on S-type neuroblastoma(NB) cell lines and its role in NB tumorigenesis were investigated.Immunohistochemistry was used to detect the expression of Shh pathway components— Patched1(PTCH1) and Gli1 in 40 human primary NB samples.Western blotting and RT-PCR were used to examine the protein expression and mRNA levels of PTCH1 and Gli1 in three kinds of S-type NB cell lines(SK-N-AS,SK-N-SH and SHEP1),respectively.Exogenous Shh was administrated to activate Shh signaling pathway while cyclopamine was used as a selective antagonist of Shh pathway.S-type NB cell lines were treated with different concentrations of Shh or/and cyclopamine for different durations.Cell viability was measured by using MTT method.Apoptosis rate and cell cycle were assayed by flow cytometry.The xenograft experiments were used to evaluate the role of Shh pathway in tumor growth in immunodeficient mice.High-level expression of PTCH1 and Gli1 was detected in both NB samples and S-type NB cell lines.Cyclopamine decreased the survival rate of the three cell lines while Shh increased it,and the inhibition effects of cyclopamine could be partially reversed by shh pre-treatment.Cyclopamine induced the cell apoptosis and the cell cycle arrest in G0/G1 phase,while Shh induced the reverse effects and could partially prevent effects of cyclopamine.Cyclopamine could also inhibit the growth of NB in vivo.Our studies revealed that activation of the Shh pathway is important for survival and proliferation of S-type NB cells in vivo and in vitro through affecting cell apoptosis and cell cycle,suggesting a new therapeutic approach to NB.展开更多
Staphylococcus aureus typing using gene encoding protein A (spa typing) seems to have a high potential discriminatory power for typing this bacterium. This study was designed based on spa typing method to compare the ...Staphylococcus aureus typing using gene encoding protein A (spa typing) seems to have a high potential discriminatory power for typing this bacterium. This study was designed based on spa typing method to compare the S. aureus types among healthy carrier vs patients, and MRSA vs MSSA isolates. Method: This study was carried out on 182 spa typeable S. aureus isolates, including 52 MRSA. DNA was extracted by phenol chloroform-isoamyl alcohol method and it was amplified by specific primer of polymorphic X region of spa. Spa types were determined by Ridom Staph Type software. The spa types distribution among MRSA vs MSSA and healthy carrier vs patients, isolates were statistically compared by X2 method and P < 0.05 was considered as significant. Result: The most common types of spa in our region were t037 (18.3%) and t937 (13.9%) from 50 spa types which were identified in this study. spa types in this study were isolated from various age groups but t660 spa types were only isolated from children. Distribution of all spa types among MRSA and MSSA isolates was 16 and 38 types, respectively which is significant. In this study we found seven new spa types (belong to twelve isolates) which are reported for the first time. In 5 out of the above 7 new types the 24 bp repeated sequences in spa gene X region were already recognized but their 24 bp arrangement is introduced in our present investigation. In the remaining 2 new types we found new 24 bp nucleotide sequences which are also introduced for the first time in our present study. Conclusion: The distribution of spa types in MSSA strains was significantly higher than MRSA isolates, but there are not any specific spa types for discrimination between MRSA and MSSA. The novelty of our study is the introducing 7 new spa types including 2 new 24 bp repeated sequences in the X region of spa gene.展开更多
A generalized Gauss-type quadrature formula is introduced, which assists in selection of collocation points in pseudospectral method for differential equations with two-point derivative boundary conditions. Some resul...A generalized Gauss-type quadrature formula is introduced, which assists in selection of collocation points in pseudospectral method for differential equations with two-point derivative boundary conditions. Some results on the related Jacobi interpolation are established. A pseudospectral scheme is proposed for the Kuramoto-Sivashisky equation. A skew symmetric decomposition is used for dealing with the nonlinear convection term. The stability and convergence of the proposed scheme are proved. The error estimates are obtained. Numerical results show the efficiency of this approach.展开更多
The main purpose of this survey paper is to point out some very recent developments on Simpson’s inequality for strongly extended s-convex function. Firstly, the concept of strongly extended s-convex function is intr...The main purpose of this survey paper is to point out some very recent developments on Simpson’s inequality for strongly extended s-convex function. Firstly, the concept of strongly extended s-convex function is introduced. Next a new identity is also established. Finally, by this identity and H?lder’s inequality, some new Simpson type for the product of strongly extended s-convex function are obtained.展开更多
基金Supported by the NNSF of China(10771064, 11101139)Supported by the NSF of Zhejiang Province(Y7080197, Y6090036, Y6100219)Supported by the Foundation of Creative Group in Colleges and Universities of Zhejiang Province(T200924)
文摘This paper deals with the boundedness and compactness of the compositionintegral type operators T g, from F (p, q, s) spaces to(little) Bloch-type spaces in the unit ball of C n , where Tg,φf(z) =∫01fφ(tz)Rg(tz)(dt)/t , z ∈ B, g ∈ H(B) and φ∈H(B, B).
基金Funded by National Social Science Foundation of China(16CGL018)the Soft Science Research Funds for Chengdu Science and Technology Project(2015-RK00-00206-ZF)the National United Engineering Laboratory of Integrated and Intelligent Transportation,Southwest Jiaotong University,China
文摘Product storage policy, single picking volume and picking routing are the three factors of vital importance that affect the efficiency of a crane to pick goods in automated storage and retrieval systems(AS/RS). Comparative experiments on picking efficiency were conducted targeting picking operation with order of 1 to 20. Based on dedicated and random storage policies, 4 picking methods of patching-based, S-type, return-type and optimized-type routes were used and compared in the experiments. The results show that either the dedicated policy or the random policy was applied, crane worked most efficiently with optimizedtype route, followed by S-type path, patching-based path, and return-type path. When the number of orders in a single picking is larger(more than 5), the random storage policy is preferable to the dedicated policy.
基金Supported by the National Natural Science Foundation of China (10771064)the Natural Science Foundation of Zhejiang province (Y6090036+1 种基金Y7080197,Y606197)the Foundation of Department of Education of Zhejiang Province (20070482)
文摘This paper deals with the boundedness and compactness of the weighted composition operators from the F（p, q, s） spaces, including Hardy space, Bergman space, Qp space, BMOA space, Besov space and α-Bloch space, to Bers-type spaces Hv^∞（ or little Bers-type spaces Hv,o∞ ）, where v is normal.
基金supported by a grant from the National Natural Sciences Foundation of China (No.30600189)
文摘The effects of Sonic hedgehog(Shh) signaling pathway activation on S-type neuroblastoma(NB) cell lines and its role in NB tumorigenesis were investigated.Immunohistochemistry was used to detect the expression of Shh pathway components— Patched1(PTCH1) and Gli1 in 40 human primary NB samples.Western blotting and RT-PCR were used to examine the protein expression and mRNA levels of PTCH1 and Gli1 in three kinds of S-type NB cell lines(SK-N-AS,SK-N-SH and SHEP1),respectively.Exogenous Shh was administrated to activate Shh signaling pathway while cyclopamine was used as a selective antagonist of Shh pathway.S-type NB cell lines were treated with different concentrations of Shh or/and cyclopamine for different durations.Cell viability was measured by using MTT method.Apoptosis rate and cell cycle were assayed by flow cytometry.The xenograft experiments were used to evaluate the role of Shh pathway in tumor growth in immunodeficient mice.High-level expression of PTCH1 and Gli1 was detected in both NB samples and S-type NB cell lines.Cyclopamine decreased the survival rate of the three cell lines while Shh increased it,and the inhibition effects of cyclopamine could be partially reversed by shh pre-treatment.Cyclopamine induced the cell apoptosis and the cell cycle arrest in G0/G1 phase,while Shh induced the reverse effects and could partially prevent effects of cyclopamine.Cyclopamine could also inhibit the growth of NB in vivo.Our studies revealed that activation of the Shh pathway is important for survival and proliferation of S-type NB cells in vivo and in vitro through affecting cell apoptosis and cell cycle,suggesting a new therapeutic approach to NB.
文摘Staphylococcus aureus typing using gene encoding protein A (spa typing) seems to have a high potential discriminatory power for typing this bacterium. This study was designed based on spa typing method to compare the S. aureus types among healthy carrier vs patients, and MRSA vs MSSA isolates. Method: This study was carried out on 182 spa typeable S. aureus isolates, including 52 MRSA. DNA was extracted by phenol chloroform-isoamyl alcohol method and it was amplified by specific primer of polymorphic X region of spa. Spa types were determined by Ridom Staph Type software. The spa types distribution among MRSA vs MSSA and healthy carrier vs patients, isolates were statistically compared by X2 method and P < 0.05 was considered as significant. Result: The most common types of spa in our region were t037 (18.3%) and t937 (13.9%) from 50 spa types which were identified in this study. spa types in this study were isolated from various age groups but t660 spa types were only isolated from children. Distribution of all spa types among MRSA and MSSA isolates was 16 and 38 types, respectively which is significant. In this study we found seven new spa types (belong to twelve isolates) which are reported for the first time. In 5 out of the above 7 new types the 24 bp repeated sequences in spa gene X region were already recognized but their 24 bp arrangement is introduced in our present investigation. In the remaining 2 new types we found new 24 bp nucleotide sequences which are also introduced for the first time in our present study. Conclusion: The distribution of spa types in MSSA strains was significantly higher than MRSA isolates, but there are not any specific spa types for discrimination between MRSA and MSSA. The novelty of our study is the introducing 7 new spa types including 2 new 24 bp repeated sequences in the X region of spa gene.
文摘A generalized Gauss-type quadrature formula is introduced, which assists in selection of collocation points in pseudospectral method for differential equations with two-point derivative boundary conditions. Some results on the related Jacobi interpolation are established. A pseudospectral scheme is proposed for the Kuramoto-Sivashisky equation. A skew symmetric decomposition is used for dealing with the nonlinear convection term. The stability and convergence of the proposed scheme are proved. The error estimates are obtained. Numerical results show the efficiency of this approach.
文摘The main purpose of this survey paper is to point out some very recent developments on Simpson’s inequality for strongly extended s-convex function. Firstly, the concept of strongly extended s-convex function is introduced. Next a new identity is also established. Finally, by this identity and H?lder’s inequality, some new Simpson type for the product of strongly extended s-convex function are obtained.
