The mutual coupling between neurons in a realistic neuronal system is much complex, and a two-layer neuronal network is designed to investigate the transition of electric activities of neurons. The Hindmarsh–Rose neu...The mutual coupling between neurons in a realistic neuronal system is much complex, and a two-layer neuronal network is designed to investigate the transition of electric activities of neurons. The Hindmarsh–Rose neuron model is used to describe the local dynamics of each neuron, and neurons in the two-layer networks are coupled in dislocated type. The coupling intensity between two-layer networks, and the coupling ratio(Pro), which defines the percentage involved in the coupling in each layer, are changed to observe the synchronization transition of collective behaviors in the two-layer networks. It is found that the two-layer networks of neurons becomes synchronized with increasing the coupling intensity and coupling ratio(Pro) beyond certain thresholds. An ordered wave in the first layer is useful to wake up the rest state in the second layer, or suppress the spatiotemporal state in the second layer under coupling by generating target wave or spiral waves. And the scheme of dislocation coupling can be used to suppress spatiotemporal chaos and excite quiescent neurons.展开更多
Network Intrusion Detection System(NIDS)detection of minority class attacks is always a difficult task when dealing with attacks in complex network environments.To improve the detection capability of minority-class at...Network Intrusion Detection System(NIDS)detection of minority class attacks is always a difficult task when dealing with attacks in complex network environments.To improve the detection capability of minority-class attacks,this study proposes an intrusion detection method based on a two-layer structure.The first layer employs a CNN-BiLSTM model incorporating an attention mechanism to classify network traffic into normal traffic,majority class attacks,and merged minority class attacks.The second layer further segments the minority class attacks through Stacking ensemble learning.The datasets are selected from the generic network dataset CIC-IDS2017,NSL-KDD,and the industrial network dataset Mississippi Gas Pipeline dataset to enhance the generalization and practical applicability of the model.Experimental results show that the proposed model achieves an overall detection accuracy of 99%,99%,and 95%on the CIC-IDS2017,NSL-KDD,and industrial network datasets,respectively.It also significantly outperforms traditional methods in terms of detection accuracy and recall rate for minority class attacks.Compared with the single-layer deep learning model,the two-layer structure effectively reduces the false alarm rate while improving the minority-class attack detection performance.The research in this paper not only improves the adaptability of NIDS to complex network environments but also provides a new solution for minority-class attack detection in industrial network security.展开更多
Neuronal soma segmentation plays a crucial role in neuroscience applications.However,the fine structure,such as boundaries,small-volume neuronal somata and fibers,are commonly present in cell images,which pose a chall...Neuronal soma segmentation plays a crucial role in neuroscience applications.However,the fine structure,such as boundaries,small-volume neuronal somata and fibers,are commonly present in cell images,which pose a challenge for accurate segmentation.In this paper,we propose a 3D semantic segmentation network for neuronal soma segmentation to address this issue.Using an encoding-decoding structure,we introduce a Multi-Scale feature extraction and Adaptive Weighting fusion module(MSAW)after each encoding block.The MSAW module can not only emphasize the fine structures via an upsampling strategy,but also provide pixel-wise weights to measure the importance of the multi-scale features.Additionally,a dynamic convolution instead of normal convolution is employed to better adapt the network to input data with different distributions.The proposed MSAW-based semantic segmentation network(MSAW-Net)was evaluated on three neuronal soma images from mouse brain and one neuronal soma image from macaque brain,demonstrating the efficiency of the proposed method.It achieved an F1 score of 91.8%on Fezf2-2A-CreER dataset,97.1%on LSL-H2B-GFP dataset,82.8%on Thy1-EGFP-Mline dataset,and 86.9%on macaque dataset,achieving improvements over the 3D U-Net model by 3.1%,3.3%,3.9%,and 2.3%,respectively.展开更多
The brain is a complex network system in which a large number of neurons are widely connected to each other and transmit signals to each other.The memory characteristic of memristors makes them suitable for simulating...The brain is a complex network system in which a large number of neurons are widely connected to each other and transmit signals to each other.The memory characteristic of memristors makes them suitable for simulating neuronal synapses with plasticity.In this paper,a memristor is used to simulate a synapse,a discrete small-world neuronal network is constructed based on Rulkov neurons and its dynamical behavior is explored.We explore the influence of system parameters on the dynamical behaviors of the discrete small-world network,and the system shows a variety of firing patterns such as spiking firing and triangular burst firing when the neuronal parameterαis changed.The results of a numerical simulation based on Matlab show that the network topology can affect the synchronous firing behavior of the neuronal network,and the higher the reconnection probability and number of the nearest neurons,the more significant the synchronization state of the neurons.In addition,by increasing the coupling strength of memristor synapses,synchronization performance is promoted.The results of this paper can boost research into complex neuronal networks coupled with memristor synapses and further promote the development of neuroscience.展开更多
Effective small object detection is crucial in various applications including urban intelligent transportation and pedestrian detection.However,small objects are difficult to detect accurately because they contain les...Effective small object detection is crucial in various applications including urban intelligent transportation and pedestrian detection.However,small objects are difficult to detect accurately because they contain less information.Many current methods,particularly those based on Feature Pyramid Network(FPN),address this challenge by leveraging multi-scale feature fusion.However,existing FPN-based methods often suffer from inadequate feature fusion due to varying resolutions across different layers,leading to suboptimal small object detection.To address this problem,we propose the Two-layerAttention Feature Pyramid Network(TA-FPN),featuring two key modules:the Two-layer Attention Module(TAM)and the Small Object Detail Enhancement Module(SODEM).TAM uses the attention module to make the network more focused on the semantic information of the object and fuse it to the lower layer,so that each layer contains similar semantic information,to alleviate the problem of small object information being submerged due to semantic gaps between different layers.At the same time,SODEM is introduced to strengthen the local features of the object,suppress background noise,enhance the information details of the small object,and fuse the enhanced features to other feature layers to ensure that each layer is rich in small object information,to improve small object detection accuracy.Our extensive experiments on challenging datasets such as Microsoft Common Objects inContext(MSCOCO)and Pattern Analysis Statistical Modelling and Computational Learning,Visual Object Classes(PASCAL VOC)demonstrate the validity of the proposedmethod.Experimental results show a significant improvement in small object detection accuracy compared to state-of-theart detectors.展开更多
Synchronous firing of neurons is thought to be important for information communication in neuronal networks. This paper investigates the complete and phase synchronization in a heterogeneous small-world chaotic Hindma...Synchronous firing of neurons is thought to be important for information communication in neuronal networks. This paper investigates the complete and phase synchronization in a heterogeneous small-world chaotic Hindmarsh Rose neuronal network. The effects of various network parameters on synchronization behaviour are discussed with some biological explanations. Complete synchronization of small-world neuronal networks is studied theoretically by the master stability function method. It is shown that the coupling strength necessary for complete or phase synchronization decreases with the neuron number, the node degree and the connection density are increased. The effect of heterogeneity of neuronal networks is also considered and it is found that the network heterogeneity has an adverse effect on synchrony.展开更多
In forest variety registration, visual traits of the plants appearance are widely used to discern different tree species. The new recognition system of leaf image strategy which based on neural network established to ...In forest variety registration, visual traits of the plants appearance are widely used to discern different tree species. The new recognition system of leaf image strategy which based on neural network established to administrate a hierarchical list of leaf images, some sorts of edge detection can be performed to identify the individual tokens of every image and the frame of the leaf can be got to differentiate the tree species. An approach based on back-propagation neuronal network is proposed and the programming language for the implementation is also Riven by using Java. The numerical simulations results have shown that the proposed leaf strategt is effective and feasible.展开更多
Delirium is a severe acute neuropsychiatric syndrome that commonly occurs in the elderly and is considered an independent risk factor for later dementia.However,given its inherent complexity,few animal models of delir...Delirium is a severe acute neuropsychiatric syndrome that commonly occurs in the elderly and is considered an independent risk factor for later dementia.However,given its inherent complexity,few animal models of delirium have been established and the mechanism underlying the onset of delirium remains elusive.Here,we conducted a comparison of three mouse models of delirium induced by clinically relevant risk factors,including anesthesia with surgery(AS),systemic inflammation,and neurotransmission modulation.We found that both bacterial lipopolysaccharide(LPS)and cholinergic receptor antagonist scopolamine(Scop)induction reduced neuronal activities in the delirium-related brain network,with the latter presenting a similar pattern of reduction as found in delirium patients.Consistently,Scop injection resulted in reversible cognitive impairment with hyperactive behavior.No loss of cholinergic neurons was found with treatment,but hippocampal synaptic functions were affected.These findings provide further clues regarding the mechanism underlying delirium onset and demonstrate the successful application of the Scop injection model in mimicking delirium-like phenotypes in mice.展开更多
The stochastic resonance in paced time-delayed scale-free FitzHugh--Nagumo （FHN） neuronal networks is investigated. We show that an intermediate intensity of additive noise is able to optimally assist the pacemaker ...The stochastic resonance in paced time-delayed scale-free FitzHugh--Nagumo （FHN） neuronal networks is investigated. We show that an intermediate intensity of additive noise is able to optimally assist the pacemaker in imposing its rhythm on the whole ensemble. Furthermore, we reveal that appropriately tuned delays can induce stochastic multiresonances, appearing at every integer multiple of the pacemaker＇s oscillation period. We conclude that fine-tuned delay lengths and locally acting pacemakers are vital for ensuring optimal conditions for stochastic resonance on complex neuronal networks.展开更多
Spatial coherence resonance in a two-dimensional neuronal network induced by additive Gaussian coloured noise and parameter diversity is studied. We focus on the ability of additive Gaussian coloured noise and paramet...Spatial coherence resonance in a two-dimensional neuronal network induced by additive Gaussian coloured noise and parameter diversity is studied. We focus on the ability of additive Gaussian coloured noise and parameter diversity to extract a particular spatial frequency （wave number） of excitatory waves in the excitable medium of this network. We show that there exists an intermediate noise level of the coloured noise and a particular value of diversity, where a characteristic spatial frequency of the system comes forth. Hereby, it is verified that spatial coherence resonance occurs in the studied model. Furthermore, we show that the optimal noise intensity for spatial coherence resonance decays exponentially with respect to the noise correlation time. Some explanations of the observed nonlinear phenomena are also presented.展开更多
Diversity in the neurons and noise are inevitable in the real neuronal network.In this paper,parameter diversity induced spiral waves and multiple spatial coherence resonances in a two-dimensional neuronal network wit...Diversity in the neurons and noise are inevitable in the real neuronal network.In this paper,parameter diversity induced spiral waves and multiple spatial coherence resonances in a two-dimensional neuronal network without or with noise are simulated.The relationship between the multiple resonances and the multiple transitions between patterns of spiral waves are identified.The coherence degrees induced by the diversity are suppressed when noise is introduced and noise density is increased.The results suggest that natural nervous system might profit from both parameter diversity and noise,provided a possible approach to control formation and transition of spiral wave by the cooperation between the diversity and noise.展开更多
Gaussian colored noise induced spatial patterns and spatial coherence resonances in a square lattice neuronal network composed of Morris-Lecar neurons are studied.Each neuron is at resting state near a saddle-node bif...Gaussian colored noise induced spatial patterns and spatial coherence resonances in a square lattice neuronal network composed of Morris-Lecar neurons are studied.Each neuron is at resting state near a saddle-node bifurcation on invariant circle,coupled to its nearest neighbors by electronic coupling.Spiral waves with different structures and disordered spatial structures can be alternately induced within a large range of noise intensity.By calculating spatial structure function and signal-to-noise ratio(SNR),it is found that SNR values are higher when the spiral structures are simple and are lower when the spatial patterns are complex or disordered,respectively.SNR manifest multiple local maximal peaks,indicating that the colored noise can induce multiple spatial coherence resonances.The maximal SNR values decrease as the correlation time of the noise increases.These results not only provide an example of multiple resonances,but also show that Gaussian colored noise play constructive roles in neuronal network.展开更多
Research on discrete memristor-based neural networks has received much attention.However,current research mainly focuses on memristor–based discrete homogeneous neuron networks,while memristor-coupled discrete hetero...Research on discrete memristor-based neural networks has received much attention.However,current research mainly focuses on memristor–based discrete homogeneous neuron networks,while memristor-coupled discrete heterogeneous neuron networks are rarely reported.In this study,a new four-stable discrete locally active memristor is proposed and its nonvolatile and locally active properties are verified by its power-off plot and DC V–I diagram.Based on two-dimensional(2D)discrete Izhikevich neuron and 2D discrete Chialvo neuron,a heterogeneous discrete neuron network is constructed by using the proposed discrete memristor as a coupling synapse connecting the two heterogeneous neurons.Considering the coupling strength as the control parameter,chaotic firing,periodic firing,and hyperchaotic firing patterns are revealed.In particular,multiple coexisting firing patterns are observed,which are induced by different initial values of the memristor.Phase synchronization between the two heterogeneous neurons is discussed and it is found that they can achieve perfect synchronous at large coupling strength.Furthermore,the effect of Gaussian white noise on synchronization behaviors is also explored.We demonstrate that the presence of noise not only leads to the transition of firing patterns,but also achieves the phase synchronization between two heterogeneous neurons under low coupling strength.展开更多
Artificial neural networks(ANN) have been extensively researched due to their significant energy-saving benefits.Hardware implementations of ANN with dropout function would be able to avoid the overfitting problem. Th...Artificial neural networks(ANN) have been extensively researched due to their significant energy-saving benefits.Hardware implementations of ANN with dropout function would be able to avoid the overfitting problem. This letter reports a dropout neuronal unit(1R1T-DNU) based on one memristor–one electrolyte-gated transistor with an ultralow energy consumption of 25 p J/spike. A dropout neural network is constructed based on such a device and has been verified by MNIST dataset, demonstrating high recognition accuracies(> 90%) within a large range of dropout probabilities up to40%. The running time can be reduced by increasing dropout probability without a significant loss in accuracy. Our results indicate the great potential of introducing such 1R1T-DNUs in full-hardware neural networks to enhance energy efficiency and to solve the overfitting problem.展开更多
Phase transitions widely exist in nature and occur when some control parameters are changed. In neural systems, their macroscopic states are represented by the activity states of neuron populations, and phase transiti...Phase transitions widely exist in nature and occur when some control parameters are changed. In neural systems, their macroscopic states are represented by the activity states of neuron populations, and phase transitions between different activity states are closely related to corresponding functions in the brain. In particular, phase transitions to some rhythmic synchronous firing states play significant roles on diverse brain functions and disfunctions, such as encoding rhythmical external stimuli, epileptic seizure, etc. However, in previous studies, phase transitions in neuronal networks are almost driven by network parameters （e.g., external stimuli）, and there has been no investigation about the transitions between typical activity states of neuronal networks in a self-organized way by applying plastic connection weights. In this paper, we discuss phase transitions in electrically coupled and lattice-based small-world neuronal networks （LBSW networks） under spike-timing-dependent plasticity （STDP）. By applying STDP on all electrical synapses, various known and novel phase transitions could emerge in LBSW networks, particularly, the phenomenon of self-organized phase transitions （SOPTs）： repeated transitions between synchronous and asynchronous firing states. We further explore the mechanics generating SOPTs on the basis of synaptic weight dynamics.展开更多
The brain is a complex network system that has the capacity to support emotion, thought, action, learning and memory, and is characterized by constant activity, constant structural remodeling, and constant attempt to ...The brain is a complex network system that has the capacity to support emotion, thought, action, learning and memory, and is characterized by constant activity, constant structural remodeling, and constant attempt to compensate for this remodeling. The basic insight that emerges from complex network organization is that substantively different networks can share common key organizational principles. Moreover, the interdependence of network organization and behavior has been successfully demonstrated for several specific tasks. From this viewpoint, increasing experimental/clinical observations suggest that mental disorders are neural network disorders. On one hand, single psychiatric disorders arise from multiple, multifactorial molecular and cellular structural/functional alterations spreading throughout local/global circuits leading to multifaceted and heterogeneous clinical symptoms. On the other hand, various mental diseases may share functional deficits across the same neural circuit as reflected in the overlap of symptoms throughout clinical diagnoses. An integrated framework including experimental measures and clinical observations will be necessary to formulate a coherent and comprehensive understanding of how neural connectivity mediates and constraints the phenotypic expression of psychiatric disorders.展开更多
An image-reconstruction approach for optical tomography is presented,in which a two-layered BP neural network is used to distinguish the tumor location.The inverse problem is solved as optimization problem by Femlab s...An image-reconstruction approach for optical tomography is presented,in which a two-layered BP neural network is used to distinguish the tumor location.The inverse problem is solved as optimization problem by Femlab software and Levenberg–Marquardt algorithm.The concept of the average optical coefficient is proposed in this paper,which is helpful to understand the distribution of the scattering photon from tumor.The reconstructive¯µs by the trained network is reasonable for showing the changes of photon number transporting inside tumor tissue.It realized the fast reconstruction of tissue optical properties and provided optical OT with a new method.展开更多
The limited capability to regenerate new neurons following injuries of the central neural system（CNS）still remains a major challenge for basic and clinical neuroscience.Neural stem cells（NSCs）could nearly have the...The limited capability to regenerate new neurons following injuries of the central neural system（CNS）still remains a major challenge for basic and clinical neuroscience.Neural stem cells（NSCs）could nearly have the potential to differentiate into all kinds of neural cells in vitro.展开更多
Multilayer network is a frontier direction of network science research. In this paper, the cluster ring network is extended to a two-layer network model, and the inner structures of the cluster blocks are random, smal...Multilayer network is a frontier direction of network science research. In this paper, the cluster ring network is extended to a two-layer network model, and the inner structures of the cluster blocks are random, small world or scale-free. We study the influence of network scale, the interlayer linking weight and interlayer linking fraction on synchronizability. It is found that the synchronizability of the two-layer cluster ring network decreases with the increase of network size. There is an optimum value of the interlayer linking weight in the two-layer cluster ring network, which makes the synchronizability of the network reach the optimum. When the interlayer linking weight and the interlayer linking fraction are very small, the change of them will affect the synchronizability.展开更多
The phenomenon of activity synchronization in biological neural network is considered. Simulation of neurons dynamics in the 6-layer neural network with 110 elements in different regimes： regular spikes, chaotic spik...The phenomenon of activity synchronization in biological neural network is considered. Simulation of neurons dynamics in the 6-layer neural network with 110 elements in different regimes： regular spikes, chaotic spikes, regular and chaotic bursting, etc was performed. Izhykevich＇s phenomenological model that displays different types of activity inherent for real biological neurons was used for simulation. Space-time diagram for the entire network and raster plots for the whole structure and for each layer separately were built for visual inspection of neural network activity synchronization. Synchronization coefficients based on cross-correlation times of action potentials for all neurons pairs were calculated for the whole neural system and for each layer separately.展开更多
基金Supported by the National Natural Science Foundation of China under Grant Nos.11265008,11372122,and 11365014
文摘The mutual coupling between neurons in a realistic neuronal system is much complex, and a two-layer neuronal network is designed to investigate the transition of electric activities of neurons. The Hindmarsh–Rose neuron model is used to describe the local dynamics of each neuron, and neurons in the two-layer networks are coupled in dislocated type. The coupling intensity between two-layer networks, and the coupling ratio(Pro), which defines the percentage involved in the coupling in each layer, are changed to observe the synchronization transition of collective behaviors in the two-layer networks. It is found that the two-layer networks of neurons becomes synchronized with increasing the coupling intensity and coupling ratio(Pro) beyond certain thresholds. An ordered wave in the first layer is useful to wake up the rest state in the second layer, or suppress the spatiotemporal state in the second layer under coupling by generating target wave or spiral waves. And the scheme of dislocation coupling can be used to suppress spatiotemporal chaos and excite quiescent neurons.
基金supported by the Institute of Information&Communications Technology Planning&Evaluation(IITP)—Innovative Human Resource Development for Local Intellectualization program grant funded by the Korea government(MSIT)(IITP-2025-RS-2022-00156334)in part by Liaoning Province Nature Fund Project(2024-BSLH-214).
文摘Network Intrusion Detection System(NIDS)detection of minority class attacks is always a difficult task when dealing with attacks in complex network environments.To improve the detection capability of minority-class attacks,this study proposes an intrusion detection method based on a two-layer structure.The first layer employs a CNN-BiLSTM model incorporating an attention mechanism to classify network traffic into normal traffic,majority class attacks,and merged minority class attacks.The second layer further segments the minority class attacks through Stacking ensemble learning.The datasets are selected from the generic network dataset CIC-IDS2017,NSL-KDD,and the industrial network dataset Mississippi Gas Pipeline dataset to enhance the generalization and practical applicability of the model.Experimental results show that the proposed model achieves an overall detection accuracy of 99%,99%,and 95%on the CIC-IDS2017,NSL-KDD,and industrial network datasets,respectively.It also significantly outperforms traditional methods in terms of detection accuracy and recall rate for minority class attacks.Compared with the single-layer deep learning model,the two-layer structure effectively reduces the false alarm rate while improving the minority-class attack detection performance.The research in this paper not only improves the adaptability of NIDS to complex network environments but also provides a new solution for minority-class attack detection in industrial network security.
基金supported by the STI2030-Major-Projects(No.2021ZD0200104)the National Natural Science Foundations of China under Grant 61771437.
文摘Neuronal soma segmentation plays a crucial role in neuroscience applications.However,the fine structure,such as boundaries,small-volume neuronal somata and fibers,are commonly present in cell images,which pose a challenge for accurate segmentation.In this paper,we propose a 3D semantic segmentation network for neuronal soma segmentation to address this issue.Using an encoding-decoding structure,we introduce a Multi-Scale feature extraction and Adaptive Weighting fusion module(MSAW)after each encoding block.The MSAW module can not only emphasize the fine structures via an upsampling strategy,but also provide pixel-wise weights to measure the importance of the multi-scale features.Additionally,a dynamic convolution instead of normal convolution is employed to better adapt the network to input data with different distributions.The proposed MSAW-based semantic segmentation network(MSAW-Net)was evaluated on three neuronal soma images from mouse brain and one neuronal soma image from macaque brain,demonstrating the efficiency of the proposed method.It achieved an F1 score of 91.8%on Fezf2-2A-CreER dataset,97.1%on LSL-H2B-GFP dataset,82.8%on Thy1-EGFP-Mline dataset,and 86.9%on macaque dataset,achieving improvements over the 3D U-Net model by 3.1%,3.3%,3.9%,and 2.3%,respectively.
基金Project supported by the Key Projects of Hunan Provincial Department of Education (Grant No.23A0133)the Natural Science Foundation of Hunan Province (Grant No.2022JJ30572)the National Natural Science Foundations of China (Grant No.62171401)。
文摘The brain is a complex network system in which a large number of neurons are widely connected to each other and transmit signals to each other.The memory characteristic of memristors makes them suitable for simulating neuronal synapses with plasticity.In this paper,a memristor is used to simulate a synapse,a discrete small-world neuronal network is constructed based on Rulkov neurons and its dynamical behavior is explored.We explore the influence of system parameters on the dynamical behaviors of the discrete small-world network,and the system shows a variety of firing patterns such as spiking firing and triangular burst firing when the neuronal parameterαis changed.The results of a numerical simulation based on Matlab show that the network topology can affect the synchronous firing behavior of the neuronal network,and the higher the reconnection probability and number of the nearest neurons,the more significant the synchronization state of the neurons.In addition,by increasing the coupling strength of memristor synapses,synchronization performance is promoted.The results of this paper can boost research into complex neuronal networks coupled with memristor synapses and further promote the development of neuroscience.
文摘Effective small object detection is crucial in various applications including urban intelligent transportation and pedestrian detection.However,small objects are difficult to detect accurately because they contain less information.Many current methods,particularly those based on Feature Pyramid Network(FPN),address this challenge by leveraging multi-scale feature fusion.However,existing FPN-based methods often suffer from inadequate feature fusion due to varying resolutions across different layers,leading to suboptimal small object detection.To address this problem,we propose the Two-layerAttention Feature Pyramid Network(TA-FPN),featuring two key modules:the Two-layer Attention Module(TAM)and the Small Object Detail Enhancement Module(SODEM).TAM uses the attention module to make the network more focused on the semantic information of the object and fuse it to the lower layer,so that each layer contains similar semantic information,to alleviate the problem of small object information being submerged due to semantic gaps between different layers.At the same time,SODEM is introduced to strengthen the local features of the object,suppress background noise,enhance the information details of the small object,and fuse the enhanced features to other feature layers to ensure that each layer is rich in small object information,to improve small object detection accuracy.Our extensive experiments on challenging datasets such as Microsoft Common Objects inContext(MSCOCO)and Pattern Analysis Statistical Modelling and Computational Learning,Visual Object Classes(PASCAL VOC)demonstrate the validity of the proposedmethod.Experimental results show a significant improvement in small object detection accuracy compared to state-of-theart detectors.
基金supported by the National Natural Science Foundation of China (Grant No 10872014)
文摘Synchronous firing of neurons is thought to be important for information communication in neuronal networks. This paper investigates the complete and phase synchronization in a heterogeneous small-world chaotic Hindmarsh Rose neuronal network. The effects of various network parameters on synchronization behaviour are discussed with some biological explanations. Complete synchronization of small-world neuronal networks is studied theoretically by the master stability function method. It is shown that the coupling strength necessary for complete or phase synchronization decreases with the neuron number, the node degree and the connection density are increased. The effect of heterogeneity of neuronal networks is also considered and it is found that the network heterogeneity has an adverse effect on synchrony.
基金Foundation project： This paper was supported by National Natural Science Foundation of China （No. 30371126）.
文摘In forest variety registration, visual traits of the plants appearance are widely used to discern different tree species. The new recognition system of leaf image strategy which based on neural network established to administrate a hierarchical list of leaf images, some sorts of edge detection can be performed to identify the individual tokens of every image and the frame of the leaf can be got to differentiate the tree species. An approach based on back-propagation neuronal network is proposed and the programming language for the implementation is also Riven by using Java. The numerical simulations results have shown that the proposed leaf strategt is effective and feasible.
基金supported by the National Natural Science Foundation of China(82071191,82001129)Natural Science Foundation of Sichuan Province(2022NSFSC1509)+1 种基金National Clinical Research Center for Geriatrics of West China Hospital(Z2021LC001)West China Hospital 1.3.5 Project for Disciplines of Excellence(ZYYC20009)。
文摘Delirium is a severe acute neuropsychiatric syndrome that commonly occurs in the elderly and is considered an independent risk factor for later dementia.However,given its inherent complexity,few animal models of delirium have been established and the mechanism underlying the onset of delirium remains elusive.Here,we conducted a comparison of three mouse models of delirium induced by clinically relevant risk factors,including anesthesia with surgery(AS),systemic inflammation,and neurotransmission modulation.We found that both bacterial lipopolysaccharide(LPS)and cholinergic receptor antagonist scopolamine(Scop)induction reduced neuronal activities in the delirium-related brain network,with the latter presenting a similar pattern of reduction as found in delirium patients.Consistently,Scop injection resulted in reversible cognitive impairment with hyperactive behavior.No loss of cholinergic neurons was found with treatment,but hippocampal synaptic functions were affected.These findings provide further clues regarding the mechanism underlying delirium onset and demonstrate the successful application of the Scop injection model in mimicking delirium-like phenotypes in mice.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 10672140,10972001 and 10832006)Matjaz Perc individually acknowledges the Support from the Slovenian Research Agency (Grant Nos. Z1-9629 and Z1-2032-2547)
文摘The stochastic resonance in paced time-delayed scale-free FitzHugh--Nagumo （FHN） neuronal networks is investigated. We show that an intermediate intensity of additive noise is able to optimally assist the pacemaker in imposing its rhythm on the whole ensemble. Furthermore, we reveal that appropriately tuned delays can induce stochastic multiresonances, appearing at every integer multiple of the pacemaker＇s oscillation period. We conclude that fine-tuned delay lengths and locally acting pacemakers are vital for ensuring optimal conditions for stochastic resonance on complex neuronal networks.
基金Project supported by the National Natural Science Foundation of China (Grant No. 10872014)
文摘Spatial coherence resonance in a two-dimensional neuronal network induced by additive Gaussian coloured noise and parameter diversity is studied. We focus on the ability of additive Gaussian coloured noise and parameter diversity to extract a particular spatial frequency （wave number） of excitatory waves in the excitable medium of this network. We show that there exists an intermediate noise level of the coloured noise and a particular value of diversity, where a characteristic spatial frequency of the system comes forth. Hereby, it is verified that spatial coherence resonance occurs in the studied model. Furthermore, we show that the optimal noise intensity for spatial coherence resonance decays exponentially with respect to the noise correlation time. Some explanations of the observed nonlinear phenomena are also presented.
基金Supported by National Natural Science Foundation of China under Grant Nos.11072135 and 10772101the Fundamental Research Funds for the Central Universities under Grant No.GK200902025
文摘Diversity in the neurons and noise are inevitable in the real neuronal network.In this paper,parameter diversity induced spiral waves and multiple spatial coherence resonances in a two-dimensional neuronal network without or with noise are simulated.The relationship between the multiple resonances and the multiple transitions between patterns of spiral waves are identified.The coherence degrees induced by the diversity are suppressed when noise is introduced and noise density is increased.The results suggest that natural nervous system might profit from both parameter diversity and noise,provided a possible approach to control formation and transition of spiral wave by the cooperation between the diversity and noise.
基金Supported by National Natural Science Foundation of China under Grant Nos. 11072135 and 10772101the Fundamental Research Funds for the Central Universities under Grant No. GK200902025
文摘Gaussian colored noise induced spatial patterns and spatial coherence resonances in a square lattice neuronal network composed of Morris-Lecar neurons are studied.Each neuron is at resting state near a saddle-node bifurcation on invariant circle,coupled to its nearest neighbors by electronic coupling.Spiral waves with different structures and disordered spatial structures can be alternately induced within a large range of noise intensity.By calculating spatial structure function and signal-to-noise ratio(SNR),it is found that SNR values are higher when the spiral structures are simple and are lower when the spatial patterns are complex or disordered,respectively.SNR manifest multiple local maximal peaks,indicating that the colored noise can induce multiple spatial coherence resonances.The maximal SNR values decrease as the correlation time of the noise increases.These results not only provide an example of multiple resonances,but also show that Gaussian colored noise play constructive roles in neuronal network.
基金Project supported by the National Natural Science Foundations of China(Grant Nos.62171401 and 62071411).
文摘Research on discrete memristor-based neural networks has received much attention.However,current research mainly focuses on memristor–based discrete homogeneous neuron networks,while memristor-coupled discrete heterogeneous neuron networks are rarely reported.In this study,a new four-stable discrete locally active memristor is proposed and its nonvolatile and locally active properties are verified by its power-off plot and DC V–I diagram.Based on two-dimensional(2D)discrete Izhikevich neuron and 2D discrete Chialvo neuron,a heterogeneous discrete neuron network is constructed by using the proposed discrete memristor as a coupling synapse connecting the two heterogeneous neurons.Considering the coupling strength as the control parameter,chaotic firing,periodic firing,and hyperchaotic firing patterns are revealed.In particular,multiple coexisting firing patterns are observed,which are induced by different initial values of the memristor.Phase synchronization between the two heterogeneous neurons is discussed and it is found that they can achieve perfect synchronous at large coupling strength.Furthermore,the effect of Gaussian white noise on synchronization behaviors is also explored.We demonstrate that the presence of noise not only leads to the transition of firing patterns,but also achieves the phase synchronization between two heterogeneous neurons under low coupling strength.
基金Project supported by the National Key Research and Development Program of China (Grant Nos. 2021YFA1202600 and 2023YFE0208600)in part by the National Natural Science Foundation of China (Grant Nos. 62174082, 92364106, 61921005, 92364204, and 62074075)。
文摘Artificial neural networks(ANN) have been extensively researched due to their significant energy-saving benefits.Hardware implementations of ANN with dropout function would be able to avoid the overfitting problem. This letter reports a dropout neuronal unit(1R1T-DNU) based on one memristor–one electrolyte-gated transistor with an ultralow energy consumption of 25 p J/spike. A dropout neural network is constructed based on such a device and has been verified by MNIST dataset, demonstrating high recognition accuracies(> 90%) within a large range of dropout probabilities up to40%. The running time can be reduced by increasing dropout probability without a significant loss in accuracy. Our results indicate the great potential of introducing such 1R1T-DNUs in full-hardware neural networks to enhance energy efficiency and to solve the overfitting problem.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11135001 and 11174034)
文摘Phase transitions widely exist in nature and occur when some control parameters are changed. In neural systems, their macroscopic states are represented by the activity states of neuron populations, and phase transitions between different activity states are closely related to corresponding functions in the brain. In particular, phase transitions to some rhythmic synchronous firing states play significant roles on diverse brain functions and disfunctions, such as encoding rhythmical external stimuli, epileptic seizure, etc. However, in previous studies, phase transitions in neuronal networks are almost driven by network parameters （e.g., external stimuli）, and there has been no investigation about the transitions between typical activity states of neuronal networks in a self-organized way by applying plastic connection weights. In this paper, we discuss phase transitions in electrically coupled and lattice-based small-world neuronal networks （LBSW networks） under spike-timing-dependent plasticity （STDP）. By applying STDP on all electrical synapses, various known and novel phase transitions could emerge in LBSW networks, particularly, the phenomenon of self-organized phase transitions （SOPTs）： repeated transitions between synchronous and asynchronous firing states. We further explore the mechanics generating SOPTs on the basis of synaptic weight dynamics.
文摘The brain is a complex network system that has the capacity to support emotion, thought, action, learning and memory, and is characterized by constant activity, constant structural remodeling, and constant attempt to compensate for this remodeling. The basic insight that emerges from complex network organization is that substantively different networks can share common key organizational principles. Moreover, the interdependence of network organization and behavior has been successfully demonstrated for several specific tasks. From this viewpoint, increasing experimental/clinical observations suggest that mental disorders are neural network disorders. On one hand, single psychiatric disorders arise from multiple, multifactorial molecular and cellular structural/functional alterations spreading throughout local/global circuits leading to multifaceted and heterogeneous clinical symptoms. On the other hand, various mental diseases may share functional deficits across the same neural circuit as reflected in the overlap of symptoms throughout clinical diagnoses. An integrated framework including experimental measures and clinical observations will be necessary to formulate a coherent and comprehensive understanding of how neural connectivity mediates and constraints the phenotypic expression of psychiatric disorders.
基金National Nature Sci-ence Foundation of China(Grant No.30671997).
文摘An image-reconstruction approach for optical tomography is presented,in which a two-layered BP neural network is used to distinguish the tumor location.The inverse problem is solved as optimization problem by Femlab software and Levenberg–Marquardt algorithm.The concept of the average optical coefficient is proposed in this paper,which is helpful to understand the distribution of the scattering photon from tumor.The reconstructive¯µs by the trained network is reasonable for showing the changes of photon number transporting inside tumor tissue.It realized the fast reconstruction of tissue optical properties and provided optical OT with a new method.
基金supported by National Program on Key Basic Research Project(973 Programs 2015CB755605)National Natural Science Foundation of China(81471312)
文摘The limited capability to regenerate new neurons following injuries of the central neural system（CNS）still remains a major challenge for basic and clinical neuroscience.Neural stem cells（NSCs）could nearly have the potential to differentiate into all kinds of neural cells in vitro.
文摘Multilayer network is a frontier direction of network science research. In this paper, the cluster ring network is extended to a two-layer network model, and the inner structures of the cluster blocks are random, small world or scale-free. We study the influence of network scale, the interlayer linking weight and interlayer linking fraction on synchronizability. It is found that the synchronizability of the two-layer cluster ring network decreases with the increase of network size. There is an optimum value of the interlayer linking weight in the two-layer cluster ring network, which makes the synchronizability of the network reach the optimum. When the interlayer linking weight and the interlayer linking fraction are very small, the change of them will affect the synchronizability.
文摘The phenomenon of activity synchronization in biological neural network is considered. Simulation of neurons dynamics in the 6-layer neural network with 110 elements in different regimes： regular spikes, chaotic spikes, regular and chaotic bursting, etc was performed. Izhykevich＇s phenomenological model that displays different types of activity inherent for real biological neurons was used for simulation. Space-time diagram for the entire network and raster plots for the whole structure and for each layer separately were built for visual inspection of neural network activity synchronization. Synchronization coefficients based on cross-correlation times of action potentials for all neurons pairs were calculated for the whole neural system and for each layer separately.
