Objective: To research the clinical application of two-dimensional speckle tracking imaging (2D-STI) in quantitative assessment of left ventricular function in patients with obstructive sleep apnea-hypopnea syndrome (...Objective: To research the clinical application of two-dimensional speckle tracking imaging (2D-STI) in quantitative assessment of left ventricular function in patients with obstructive sleep apnea-hypopnea syndrome (OSAS). Method: From July 2016 to December 2018, 86 patients with OSAS were selected as OSAS group. According to sleep apnea hypopnea index (AHI), they were divided into mild OSAS group (24 cases), moderate OSAS group (29 cases) and severe OSAS group (33 cases). Another 50 healthy volunteers who underwent physical examination in our hospital during the same period were selected as the control group. The left ventricular function of all patients was quantitatively assessed by 2D-STI. The left ventricular function of all patients was quantitatively assessed by 2D-STI. The results of routine echocardiography and left ventricular global strain parameters of the OSAS group, the control group and the OSAS patients with different severity were compared and analyzed. Result: There were no significant differences in the levels of left ventricular ejection fraction (LVEF), left ventricular end diastolic diameter (LVEDd), left ventricular end systolic diameter (LVESd) between the two groups and OSAS patients with different severity (P>0.05). The levels of IVST, LVPW and LVMI in the OSAS group were significantly higher than those in the control group, the levels of end-diastolic interventricular septal thickness (IVS), left ventricular posterior wall thickness (LVPW), left ventricular mass index (LVMI) in the severe OSAS group were significantly higher than those in the mild and moderate OSAS group, and the levels of IVST, LVPW and LVMI in the moderate OSAS group were significantly higher than those in the mild OSAS group, there were significant differences between groups (P<0.05). The levels of GLS, GRS and GCS in the OSAS group were significantly lower than those in the control group (P<0.05). GLS, GRS and GCS levels in the severe OSAS group were significantly lower than those in the mild OSAS group and the moderate OSAS group, while the levels of global longitudinal strain (GLS), global radial strain (GRS) and global circumferential strain (GCS) in the moderate OSAS group were significantly lower than those in the mild OSAS group (P<0.05). Conclusion: The left ventricular systolic function of OSAS patients is obviously impaired. Left ventricular function in OSAS patients can be assessed timely and accurately by two-dimensional speckle tracking imaging.展开更多
目的分析二维斑点追踪成像(two-dimensional speckle-tracking imaging,2D-STI)参数、QT间期离散度(dispersion of QT interval,QTd)与AMI(acute myocardial infarction,AMI)患者经皮冠状动脉介入(percutaneous coronary intervention,P...目的分析二维斑点追踪成像(two-dimensional speckle-tracking imaging,2D-STI)参数、QT间期离散度(dispersion of QT interval,QTd)与AMI(acute myocardial infarction,AMI)患者经皮冠状动脉介入(percutaneous coronary intervention,PCI)治疗后主要不良心血管事件(major adverse cardiovascular events,MACE)的关系。方法选取2022年3月至2024年11月邢台市中心医院收治的115例AMI患者作为病例组,同时选取在本院进行体检的108名健康志愿者为对照组。根据是否发生MACE将病例组患者分为MACE组(n=36)和无MACE组(n=79)。比较病例组和对照组、MACE组和无MACE组患者的2D-STI参数、QTd,分析影响AMI患者PCI治疗后MACE发生的独立危险因素,并利用Spearman相关性分析对2D-STI参数、QTd与AMI患者PCI治疗后MACE发生的关系进行分析。结果与对照组比较,病例组患者的NN间期标准差(standard deviation of NN interval,SDNN)、震荡斜率(slope of oscillation,TS)、左心房平均峰值应变率(overall systolic mean peak strain,mSs)、计算左心房被动射血分数(left atrial passive ejection fraction,LAPEF)、左心房总射血分数(total left atrial ejection fraction,LATEF)、左心房收缩期平均峰值应变率(left atrial strain rate in the left ventricular systolic,mSRs)、左心房主动射血分数(left atrial active ejection fraction,LAAEF)、左心房舒张早期平均峰值应变率(left atrial strain rate in the early left ventricular diastole,mSRe)、左心房舒张晚期平均峰值应变率(left atrial strain rate in the late left ventricular diastole,mSRa)下降,校正QTd(correct of QTd,QTcd)、QTd、震荡初始(oscillatory inception,TO)、最小左心房容积(minimum left atrial volume,LAV_(min))、最大左心房容积(maximum left atrial volume,LAV_(max))、左心房收缩前容积(left atrial presystolic volume,LAVp)上升,差异均有统计学意义(P<0.05)。另外,MACE组和无MACE组患者的病变支数、肌酸激酶同工酶(creatine kinase isoenzyme MB,CK-MB)、氨基末端脑钠肽前体(N-terminal pro-B type natriuretic peptide,NT-proBNP)、mSs、LAPEF、LATEF、mSRs、LAAEF、mSRe、mSRa、LAV_(min)、LAV_(max)、LAVp、SDNN、TS、QTcd、QTd、TO比较,差异有统计学意义(P<0.05)。多因素Logistic回归分析结果显示以上指标均是影响患者PCI治疗后MACE发生的危险因素。Spearman相关性分析结果显示,AMI患者PCI治疗后MACE的发生与QTd、LAV_(min)、LAV_(max)、LAVp、mSRa呈正相关(r=0.447、0.319、0.407、0.441、0.339,P<0.05),与mSs、LAPEF、LATEF、mSRs、LAAEF、mSRe呈负相关(r=-0.228、-0.319、-0.333、-0.282、-0.317、-0.337,P<0.05)。结论AMI患者2D-STI参数、QTd存在差异,并与PCI治疗后MACE发生有关,可作为患者PCI治疗后MACE发生的临床检测指标。展开更多
文摘Objective: To research the clinical application of two-dimensional speckle tracking imaging (2D-STI) in quantitative assessment of left ventricular function in patients with obstructive sleep apnea-hypopnea syndrome (OSAS). Method: From July 2016 to December 2018, 86 patients with OSAS were selected as OSAS group. According to sleep apnea hypopnea index (AHI), they were divided into mild OSAS group (24 cases), moderate OSAS group (29 cases) and severe OSAS group (33 cases). Another 50 healthy volunteers who underwent physical examination in our hospital during the same period were selected as the control group. The left ventricular function of all patients was quantitatively assessed by 2D-STI. The left ventricular function of all patients was quantitatively assessed by 2D-STI. The results of routine echocardiography and left ventricular global strain parameters of the OSAS group, the control group and the OSAS patients with different severity were compared and analyzed. Result: There were no significant differences in the levels of left ventricular ejection fraction (LVEF), left ventricular end diastolic diameter (LVEDd), left ventricular end systolic diameter (LVESd) between the two groups and OSAS patients with different severity (P>0.05). The levels of IVST, LVPW and LVMI in the OSAS group were significantly higher than those in the control group, the levels of end-diastolic interventricular septal thickness (IVS), left ventricular posterior wall thickness (LVPW), left ventricular mass index (LVMI) in the severe OSAS group were significantly higher than those in the mild and moderate OSAS group, and the levels of IVST, LVPW and LVMI in the moderate OSAS group were significantly higher than those in the mild OSAS group, there were significant differences between groups (P<0.05). The levels of GLS, GRS and GCS in the OSAS group were significantly lower than those in the control group (P<0.05). GLS, GRS and GCS levels in the severe OSAS group were significantly lower than those in the mild OSAS group and the moderate OSAS group, while the levels of global longitudinal strain (GLS), global radial strain (GRS) and global circumferential strain (GCS) in the moderate OSAS group were significantly lower than those in the mild OSAS group (P<0.05). Conclusion: The left ventricular systolic function of OSAS patients is obviously impaired. Left ventricular function in OSAS patients can be assessed timely and accurately by two-dimensional speckle tracking imaging.
文摘目的分析二维斑点追踪成像(two-dimensional speckle-tracking imaging,2D-STI)参数、QT间期离散度(dispersion of QT interval,QTd)与AMI(acute myocardial infarction,AMI)患者经皮冠状动脉介入(percutaneous coronary intervention,PCI)治疗后主要不良心血管事件(major adverse cardiovascular events,MACE)的关系。方法选取2022年3月至2024年11月邢台市中心医院收治的115例AMI患者作为病例组,同时选取在本院进行体检的108名健康志愿者为对照组。根据是否发生MACE将病例组患者分为MACE组(n=36)和无MACE组(n=79)。比较病例组和对照组、MACE组和无MACE组患者的2D-STI参数、QTd,分析影响AMI患者PCI治疗后MACE发生的独立危险因素,并利用Spearman相关性分析对2D-STI参数、QTd与AMI患者PCI治疗后MACE发生的关系进行分析。结果与对照组比较,病例组患者的NN间期标准差(standard deviation of NN interval,SDNN)、震荡斜率(slope of oscillation,TS)、左心房平均峰值应变率(overall systolic mean peak strain,mSs)、计算左心房被动射血分数(left atrial passive ejection fraction,LAPEF)、左心房总射血分数(total left atrial ejection fraction,LATEF)、左心房收缩期平均峰值应变率(left atrial strain rate in the left ventricular systolic,mSRs)、左心房主动射血分数(left atrial active ejection fraction,LAAEF)、左心房舒张早期平均峰值应变率(left atrial strain rate in the early left ventricular diastole,mSRe)、左心房舒张晚期平均峰值应变率(left atrial strain rate in the late left ventricular diastole,mSRa)下降,校正QTd(correct of QTd,QTcd)、QTd、震荡初始(oscillatory inception,TO)、最小左心房容积(minimum left atrial volume,LAV_(min))、最大左心房容积(maximum left atrial volume,LAV_(max))、左心房收缩前容积(left atrial presystolic volume,LAVp)上升,差异均有统计学意义(P<0.05)。另外,MACE组和无MACE组患者的病变支数、肌酸激酶同工酶(creatine kinase isoenzyme MB,CK-MB)、氨基末端脑钠肽前体(N-terminal pro-B type natriuretic peptide,NT-proBNP)、mSs、LAPEF、LATEF、mSRs、LAAEF、mSRe、mSRa、LAV_(min)、LAV_(max)、LAVp、SDNN、TS、QTcd、QTd、TO比较,差异有统计学意义(P<0.05)。多因素Logistic回归分析结果显示以上指标均是影响患者PCI治疗后MACE发生的危险因素。Spearman相关性分析结果显示,AMI患者PCI治疗后MACE的发生与QTd、LAV_(min)、LAV_(max)、LAVp、mSRa呈正相关(r=0.447、0.319、0.407、0.441、0.339,P<0.05),与mSs、LAPEF、LATEF、mSRs、LAAEF、mSRe呈负相关(r=-0.228、-0.319、-0.333、-0.282、-0.317、-0.337,P<0.05)。结论AMI患者2D-STI参数、QTd存在差异,并与PCI治疗后MACE发生有关,可作为患者PCI治疗后MACE发生的临床检测指标。
