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A Valuable and Low-Budget Process Scheme of Equivalized 1 nm Technology Node Based on 2D Materials
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作者 Yang Shen Zhejia Zhang +6 位作者 Zhujun Yao Mengge Jin Jintian Gao Yuhan Zhao Wenzhong Bao Yabin Sun He Tian 《Nano-Micro Letters》 2025年第8期294-305,共12页
Emerging two-dimensional(2D)semiconductors are among the most promising materials for ultra-scaled transistors due to their intrinsic atomic-level thickness.As the stacking process advances,the complexity and cost of ... Emerging two-dimensional(2D)semiconductors are among the most promising materials for ultra-scaled transistors due to their intrinsic atomic-level thickness.As the stacking process advances,the complexity and cost of nanosheet field-effect transistors(NSFETs)and complementary FET(CFET)continue to rise.The 1 nm technology node is going to be based on Si-CFET process according to international roadmap for devices and systems(IRDS)(2022,https://irds.ieee.org/),but not publicly confirmed,indicating that more possibilities still exist.The miniaturization advantage of 2D semiconductors motivates us to explore their potential for reducing process costs while matching the performance of next-generation nodes in terms of area,power consumption and speed.In this study,a comprehensive framework is built.A set of MoS2 NSFETs were designed and fabricated to extract the key parameters and performances.And then for benchmarking,the sizes of 2D-NSFET are scaled to a extent that both of the Si-CFET and 2D-NSFET have the same average device footprint.Under these conditions,the frequency of ultra-scaled 2D-NSFET is found to improve by 36%at a fixed power consumption.This work verifies the feasibility of replacing silicon-based CFETs of 1 nm node with 2D-NSFETs and proposes a 2D technology solution for 1 nm nodes,i.e.,“2D eq 1 nm”nodes.At the same time,thanks to the lower characteristic length of 2D semiconductors,the miniaturized 2D-NSFET achieves a 28%frequency increase at a fixed power consumption.Further,developing a standard cell library,these devices obtain a similar trend in 16-bit RISC-V CPUs.This work quantifies and highlights the advantages of 2D semiconductors in advanced nodes,offering new possibilities for the application of 2D semiconductors in high-speed and low-power integrated circuits. 展开更多
关键词 two-dimensional semiconductors 1 nm technology node Nanosheet field-effect transistors Complementary field-effect transistors Horizontal scaling
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Research on Recognition Technology of 2-Dimensional Barcode
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作者 Ronghong Chent Qingsong Zhu 《International Journal of Technology Management》 2013年第2期1-3,共3页
This paper briefly introduces the characteristics and structure of symbol QR two-dimensional code, a detailed analysis of the image processing method to identify QR code of the whole process, and the bilinear mapping ... This paper briefly introduces the characteristics and structure of symbol QR two-dimensional code, a detailed analysis of the image processing method to identify QR code of the whole process, and the bilinear mapping method is applied to image correction, the final steps of decoding are given. The actual test results show that, the design algorithm has theoretical and practical, this recognition system can correctly read QR code, and has high recognition rate and recognition speed, has practical value and application prospect. 展开更多
关键词 two-dimensional barcode quick response code Image Recognition technology
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Hydrophobic long-chain two-dimensional perovskite scintillators for underwater X-ray imaging 被引量:3
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作者 Jin-Xiao Zheng Zi-An Zhou +6 位作者 Tiao Feng Hui Li Cheng-Hua Sun NüWang Yang Tian Yong Zhao Shu-Yun Zhou 《Rare Metals》 SCIE EI CAS CSCD 2024年第1期175-185,共11页
The underwater X-ray imaging technology development is significant to subaqueous target reconnaissance/detection/identification, subfluvial archaeology,submerged resource exploration, etc. As the core of X-ray imaging... The underwater X-ray imaging technology development is significant to subaqueous target reconnaissance/detection/identification, subfluvial archaeology,submerged resource exploration, etc. As the core of X-ray imaging detection, the scintillator has been plagued by inherent moisture absorption and decomposition, and strict requirements for seamless packaging and waterproofing.Here, we designed a manganese-doped two-dimensional(2D) perovskite scintillator modified by hydrophobic longchain organic amine through the combination of component and doping engineering. The modified perovskites show high water repellency that can be used as an underwater X-ray scintillator. X-ray images of aquatic organisms or other objects with a high spatial resolution of10 lp·mm^(-1) at a big view field(32 mm × 32 mm) were obtained by scintillation screen. This hydrophobic perovskite scintillator based on molecular design is of great promise in underwater X-ray nondestructive testing technology development. 展开更多
关键词 two-dimensional perovskite HYDROPHOBIC SCINTILLATORS Underwater X-ray imaging Underwater nondestructive testing technology
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Maximum two-dimensional (u×v,4,1,3)-OOCs 被引量:2
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作者 HUANG Yue-mei CHANG Yan-xun 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2013年第3期279-289,共11页
Let Ф(u ×v, k, Aa, Ac) be the largest possible number of codewords among all two- dimensional (u ×v, k, λa, λc) optical orthogonal codes. A 2-D (u× v, k, λa, λ)-OOC with Ф(u× v, k, λ... Let Ф(u ×v, k, Aa, Ac) be the largest possible number of codewords among all two- dimensional (u ×v, k, λa, λc) optical orthogonal codes. A 2-D (u× v, k, λa, λ)-OOC with Ф(u× v, k, λa, λc) codewords is said to be maximum. In this paper, the number of codewords of a maximum 2-D (u × v, 4, 1, 3)-OOC has been determined. 展开更多
关键词 MAXIMUM two-dimensional optical orthogonal code orbit.
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Comprehensive two-dimensional river ice model based on boundary-fitted coordinate transformation method 被引量:1
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作者 Ze-yu MAO Jing YUAN +2 位作者 Jun BAO Xiao-fan PENG Guo-qiang TANG 《Water Science and Engineering》 EI CAS CSCD 2014年第1期90-105,共16页
River ice is a natural phenomenon in cold regions, influenced by meteorology, geomorphology, and hydraulic conditions. River ice processes involve complex interactions between hydrodynamic, mechanical, and thermal pro... River ice is a natural phenomenon in cold regions, influenced by meteorology, geomorphology, and hydraulic conditions. River ice processes involve complex interactions between hydrodynamic, mechanical, and thermal processes, and they are also influenced by weather and hydrologic conditions. Because natural rivers are serpentine, with bends, narrows, and straight reaches, the commonly-used one-dimensional river ice models and two-dimensional models based on the rectangular Cartesian coordinates are incapable of simulating the physical phenomena accurately. In order to accurately simulate the complicated river geometry and overcome the difficulties of numerical simulation resulting from both complex boundaries and differences between length and width scales, a two-dimensional river ice numerical model based on a boundary-fitted coordinate transformation method was developed. The presented model considers the influence of the frazil ice accumulation under ice cover and the shape of the leading edge of ice cover during the freezing process. The model is capable of determining the velocity field, the distribution of water temperature, the concentration distribution of frazil ice, the transport of floating ice, the progression, stability, and thawing of ice cover, and the transport, accumulation, and erosion of ice under ice cover. A MacCormack scheme was used to solve the equations numerically. The model was validated with field observations from the Hequ Reach of the Yellow River. Comparison of simulation results with field data indicates that the model is capable of simulating the river ice process with high accuracy. 展开更多
关键词 two-dimensional river ice numerical model boundary-fitted coordinate technology river ice process freeze-up MacCormack scheme natural river
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Chinese Telemetry Technology under Fast Development
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作者 Changjie, Shi 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 1993年第3期7-14,共8页
The history of the development of Chinese telemetry is introduced in the paper. The new telemetry ground station and the new onboard space telemetry system, with the idea of systematic design and the specification, ar... The history of the development of Chinese telemetry is introduced in the paper. The new telemetry ground station and the new onboard space telemetry system, with the idea of systematic design and the specification, are described. 展开更多
关键词 Amplitude modulation CONTROLLABILITY HISTORY Parameter estimation Phase shift keying Pulse code modulation Satellite ground stations Space applications Systems analysis technology
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Study on the Diagnostic Effect of Two-dimensional Ultrasound Imaging on Peripheral Vascular Atherosclerosis
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作者 ZHANGYanhua ZHOUHongwei +1 位作者 LIYaping HECuiyun 《外文科技期刊数据库(文摘版)医药卫生》 2022年第7期184-187,共4页
Objective: to analyze the diagnostic value of two-dimensional ultrasound imaging in peripheral vascular atherosclerosis. Methods: in this study, 100 patients with peripheral vascular atherosclerosis who were treated i... Objective: to analyze the diagnostic value of two-dimensional ultrasound imaging in peripheral vascular atherosclerosis. Methods: in this study, 100 patients with peripheral vascular atherosclerosis who were treated in our hospital from February 2020 to May 2021 were enrolled in the study. All patients were diagnosed by two-dimensional ultrasound imaging technology, and the plaque formation site, imaging manifestations, plaque types and basic diseases were analyzed. Results: for the 100 patients enrolled in this group, the ultrasonic manifestations of the patients mainly included 87 cases of rough intima, 35 cases of thickening, 12 cases of carotid intima thickening and 42 cases of rough intima. 21 plaque formation sites, 62 on the left and 59 on the right;There are 16 origins of internal carotid artery and 13 origins of common carotid artery at 22 bifurcation points and 70 bulbous points of common carotid artery. There were 49 soft spots, 45 hard spots, 4 mixed spots and 2 flat spots. Among the enrolled patients, cerebral infarction and coronary heart disease account for a large proportion, with 43 cases of cerebral infarction, accounting for 43.00%, and 39 cases of coronary heart disease, accounting for 39.00%. Conclusion: two-dimensional ultrasound imaging technology can effectively detect plaque and realize the exact diagnosis of peripheral vascular atherosclerosis. 展开更多
关键词 peripheral vascular atherosclerosis two-dimensional ultrasonic imaging technology diagnostic effec
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基于Erasure Code的分布式文件存储系统 被引量:5
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作者 潘利伟 谷建华 +1 位作者 朱靖飞 周志超 《计算机工程》 CAS CSCD 北大核心 2010年第17期45-47,共3页
在局域网环境下,实现一种基于Erasure Code的分布式文件存储系统。该系统由元数据服务器和多个文件存储节点组成,通过对元数据与文件数据分离存储以提高文件访问效率,将Erasure Code有效冗余存储技术应用于文件编解码以增强可靠性,采用... 在局域网环境下,实现一种基于Erasure Code的分布式文件存储系统。该系统由元数据服务器和多个文件存储节点组成,通过对元数据与文件数据分离存储以提高文件访问效率,将Erasure Code有效冗余存储技术应用于文件编解码以增强可靠性,采用MD5消息摘要技术保证文件完整性。对30 MB^600 MB大小的文件测试结果表明,该系统具有更高的可靠性、安全性以及资源利用率。 展开更多
关键词 分布式文件存储 ERASURE code技术 编解码 高可靠
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基于机器人应用的混凝土试件全自动抗压强度检测系统研究
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作者 刘江 孙宗波 +3 位作者 温超 刘亚齐 杜春林 杨文沁 《广东建材》 2026年第1期172-175,共4页
本文提出了一种基于工业机器人应用的混凝土试件抗压强度全自动检测系统,旨在提升检测效率和质量管理水平。该系统通过二维码技术绑定试件身份,工业机器人自动抓取并将试件送入压力试验机进行抗压强度测试。检测过程中的数据由系统自动... 本文提出了一种基于工业机器人应用的混凝土试件抗压强度全自动检测系统,旨在提升检测效率和质量管理水平。该系统通过二维码技术绑定试件身份,工业机器人自动抓取并将试件送入压力试验机进行抗压强度测试。检测过程中的数据由系统自动采集、处理并上传至生产管理系统,实现全过程的自动化管理与监控。该方法不仅大幅提高了检测效率,减少了人工干预,还通过自动化的数据处理与存储,有效避免了人为误差,确保了抗压强度数据的准确性与可靠性。此系统在提升生产自动化的同时,强化了混凝土试件抗压强度检测的质量控制,为建筑材料检测领域提供了高效、精确的解决方案。 展开更多
关键词 工业机器人 抗压强度检测 二维码技术 自动化管理 数据处理
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Perfect Code问题的加权分治算法 被引量:2
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作者 王英磊 宁爱兵 +1 位作者 支志兵 杨晓芳 《小型微型计算机系统》 CSCD 北大核心 2014年第3期594-596,共3页
加权分治技术是算法设计和分析中的一种新技术,该技术通过对处理对象设置不同的权值来更加精确的描述分支子问题规模的大小,其目的是得到最坏情况下时间复杂度更好的精确算法.Perfect Code问题是一典型的NP难题,基于分支降阶技术为其设... 加权分治技术是算法设计和分析中的一种新技术,该技术通过对处理对象设置不同的权值来更加精确的描述分支子问题规模的大小,其目的是得到最坏情况下时间复杂度更好的精确算法.Perfect Code问题是一典型的NP难题,基于分支降阶技术为其设计一个快速递归算法;同时使用加权分治技术对算法加以分析,得到一个时间复杂度为O(1.3248np(n))的精确算法,其中p(n)为问题中结点个数n的多项式函数,对比分析表明该时间复杂度低于采用传统方法得到的时间复杂度. 展开更多
关键词 加权分治技术 PERFECT code问题 分支降阶技术 算法复杂性
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Multiple bit upsets mitigation in memory by using improved hamming codes and parity codes 被引量:1
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作者 祝名 肖立伊 田欢 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2010年第5期726-730,共5页
This paper combines improved Hamming codes and parity codes to assure the reliability of memory in presence of multiple bit upsets with low cost overhead.The redundancy bits of improved Hamming codes will be appended ... This paper combines improved Hamming codes and parity codes to assure the reliability of memory in presence of multiple bit upsets with low cost overhead.The redundancy bits of improved Hamming codes will be appended at the end of data bits,which eliminates the overhead of interspersing the redundancy bits at the encoder and decoder.The reliability of memory is further enhanced by the layout architecture of redundancy bits and data bits.The proposed scheme has been implemented in Verilog and synthesized using the Synopsys tools.The results reveal that the proposed method has about 19% less area penalties and 13% less power consumption comparing with the current two-dimensional error codes,and its latency of encoder and decoder is 63% less than that of Hamming codes. 展开更多
关键词 MEMORY multiple bit upsets improved hamming codes two-dimensional error codes
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Effects of periodically varying codes on separation of multisource blended data 被引量:1
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作者 Jiao Meng-Yao Hu Tian-Yue +4 位作者 Liu Yang Yu Zhen-Zhen Liang Shang-Lin Liu Li-Chao Ji-Wei 《Applied Geophysics》 SCIE CSCD 2021年第3期331-344,432,共15页
Current exploration needs are satisfied by multisource technology,which offers low cost,high efficiency,and high precision.The delay time,which determines the separation effects of the multisource blended data,is one ... Current exploration needs are satisfied by multisource technology,which offers low cost,high efficiency,and high precision.The delay time,which determines the separation effects of the multisource blended data,is one of the most crucial parameters in the acquisition and separation of multisource data.This study uses the deblending method of multisource data based on a periodically varying cosine code and analyses the effects of the two parameters,namely,the period amplitude and period length,used in this method on the separation of the multisource blended data.Meanwhile,the obtained coherence data is used to prove the correlation between the separation of multisource data and the two parameters.Examples of synthetic and field data are adopted to demonstrate that from a qualitative perspective,increasing the amplitude of the periodic code improves the separation effect within a reasonable delay time range.When the period length varies in a suitable range,the secondary noise becomes relatively incoherent,resulting in the separation result with a higher signal-to-noise ratio(SNR).From a quantitative perspective,the significant values(Sig.)of the period amplitude and length on the SNRs are less than 0.05,verifying the correlation between the separation of multisource data and the two parameters. 展开更多
关键词 multisource technology periodically varying cosine code period amplitude period length correlation
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Latest development of display technologies 被引量:1
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作者 高洪跃 姚秋香 +7 位作者 刘攀 郑志强 刘吉成 郑华东 曾超 于瀛洁 孙涛 曾震湘 《Chinese Physics B》 SCIE EI CAS CSCD 2016年第9期1-8,共8页
In this review we will focus on recent progress in the field of two-dimensional(2D) and three-dimensional(3D)display technologies.We present the current display materials and their applications,including organic l... In this review we will focus on recent progress in the field of two-dimensional(2D) and three-dimensional(3D)display technologies.We present the current display materials and their applications,including organic light-emitting diodes(OLEDs),flexible OLEDs quantum dot light emitting diodes(QLEDs),active-matrix organic light emitting diodes(AMOLEDs),electronic paper(E-paper),curved displays,stereoscopic 3D displays,volumetric 3D displays,light field3 D displays,and holographic 3D displays.Conventional 2D display devices,such as liquid crystal devices(LCDs) often result in ambiguity in high-dimensional data images because of lacking true depth information.This review thus provides a detailed description of 3D display technologies. 展开更多
关键词 display technology two-dimensional displays three-dimensional displays holographic displays
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Emerging Technologies of Future Multimedia Coding, Analysis and Transmission
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作者 Huifang Sun Can Shen Ping Wu 《ZTE Communications》 2016年第1期1-2,共2页
Three years ago,ZTE Communications published a special issue called Emerging Technologies of Multimedia Coding,Analysis and Transmission.Over the past three years,great advances have been made in multimedia.The purpos... Three years ago,ZTE Communications published a special issue called Emerging Technologies of Multimedia Coding,Analysis and Transmission.Over the past three years,great advances have been made in multimedia.The purpose of this special issue is to report on the progress and 展开更多
关键词 HEVC Analysis and Transmission AVS Emerging technologies of Future Multimedia Coding
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Emergence of Plastidial Intergenic Spacers as Suitable DNA Barcodes for Arid Medicinal Plant <i>Rhazya stricta</i>
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作者 Samia A. Khan Mohammed N. Baeshen +1 位作者 Hassan A. Ramadan Nabih A. Baeshen 《American Journal of Plant Sciences》 2017年第8期1774-1789,共16页
The desert plant Rhazya stricta has anticancer and antimicrobial properties, and is widely used in indigenous medicines of Saudi Arabia. However, the therapeutic benefits rely on an accurate identification of this spe... The desert plant Rhazya stricta has anticancer and antimicrobial properties, and is widely used in indigenous medicines of Saudi Arabia. However, the therapeutic benefits rely on an accurate identification of this species. The authenticity of R. stricta and other medicinal plants and herbs procured from local markets can be questionable due to a lack of clear phenotypic traits. DNA barcoding is an emerging technology for rapid and accurate species identification. In this study, six candidate chloroplastid barcodes were investigated for the authentication of R. stricta. We compared the DNA sequences from fifty locally collected and five market samples of R. stricta with database sequences of R. stricta and seven closely related species. We found that the coding regions matK, rbcL, rpoB, and rpoC1 were highly similar among the taxa. By contrast, the intergenic spacers psbK-psbI and atpF-atpH were variable loci distinct for the medicinal plant R. stricta. psbK-psbI clearly discriminated R. stricta samples as an efficient single locus marker, whereas a two-locus marker combination comprising psbK-psbI + atpF-atpH was also promising according to results from the Basic Local Alignment Search Tool and a maximum likelihood gene tree generated using PHyML. Two-dimensional DNA barcodes (i.e., QR codes) for the psbK-psbI and psbK-psbI + atpF-atpH regions were created for the validation of fresh or dried R. stricta samples. 展开更多
关键词 Rhazya STRICTA Medicinal Plant DNA BARCODING matK rbcl rpoB rpoC1 atpF-atpH psbK-psbI two-dimensional DNA Barcode QR code
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Colorbit code自动识别技术在图书馆中的应用 被引量:1
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作者 有鹂 《兰台世界》 2021年第2期109-111,共3页
在全民学习的文化大背景下,人们对于自身文化素养以及精神生活的重视越来越高,图书馆的作用也开始日渐凸出,但由于我国图书馆建设尚未完全普及和成熟,在很多的二三线城市图书馆建设上还存在很大的不足,更遑论图书馆识别技术的革新和运... 在全民学习的文化大背景下,人们对于自身文化素养以及精神生活的重视越来越高,图书馆的作用也开始日渐凸出,但由于我国图书馆建设尚未完全普及和成熟,在很多的二三线城市图书馆建设上还存在很大的不足,更遑论图书馆识别技术的革新和运用。但在目前日益高涨的读书需求下,进行图书馆识别技术的革新及发展乃是时代要求。利用Colorbit code识别技术,图书馆可以实现图书自动盘点、图书自助借还、图书位置定位、图书检索等功能,基本满足了图书馆管理智能化的需求,是对图书馆的藏书资源、管理模式进行优化与整合。 展开更多
关键词 Colorbit code 自动识别技术 图书馆 应用模型
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超声导波轨底裂纹检测的信号增强技术 被引量:1
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作者 何继平 周永久 +5 位作者 钦佩 张岩 周守镇 王平 周文涛 刘勇 《城市轨道交通研究》 北大核心 2025年第4期260-263,268,共5页
[目的]导波在钢轨中的传播过程中存在抗干扰能力差和信号衰减严重问题,不利于识别轨底裂纹。为提高信噪比,有必要提出一种信号增强技术用于增强导波信号。[方法]在传统超声导波检测基础上,利用Barker码作为伪随机序列码,采用BPSK(二进... [目的]导波在钢轨中的传播过程中存在抗干扰能力差和信号衰减严重问题,不利于识别轨底裂纹。为提高信噪比,有必要提出一种信号增强技术用于增强导波信号。[方法]在传统超声导波检测基础上,利用Barker码作为伪随机序列码,采用BPSK(二进制相位编码)技术将原始激励信号经过编码调制后得到新的激励信号,实现对激励信号的扩频处理,并对采集的接收信号进行解扩。搭建超声导波轨底裂纹检测试验平台,分别对不同尺寸的钢轨轨底人工裂纹进行对比试验,分别在激励信号扩频与非扩频情况下,计算所接收导波信号的衰减系数。[结果及结论]试验结果表明,导波信号使用信号增强技术之后,相较于未经处理的原始导波信号,在传播相同距离时,衰减系数得到了明显降低,超声导波信号将能传播更远距离;相同尺寸人工裂纹所产生的影响更加明显,超声导波对钢轨轨底裂纹的检测灵敏度得到了明显提升。 展开更多
关键词 轨道交通 钢轨裂纹检测 Barker码 超声导波 信号增强技术
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大模型时代图书馆员的AI应用开发:ESSE方法论与实践探索 被引量:2
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作者 许磊 《信息与管理研究》 2025年第1期20-33,共14页
随着大语言模型的蓬勃发展,人工智能(AI)技术正经历一场深刻的民主化变革。大模型及其配套工具显著降低了技术门槛,为非技术背景人员参与AI创新开辟了新途径。本文以“图书馆员的AI应用自主开发”为主线,系统探讨了图书馆员如何在这一... 随着大语言模型的蓬勃发展,人工智能(AI)技术正经历一场深刻的民主化变革。大模型及其配套工具显著降低了技术门槛,为非技术背景人员参与AI创新开辟了新途径。本文以“图书馆员的AI应用自主开发”为主线,系统探讨了图书馆员如何在这一技术变革中从观望走向实践。从机遇与挑战的认知启程,到技术民主化带来的探索可能,再到必要工具与技能的准备,文章全面梳理了图书馆员迈向AI开发的历程。基于实践经验,本文提出了面向图书馆员的AI开发ESSE方法论(Explore探索、Specify详述、Scrutinize评估、Enhance强化),为零基础图书馆员提供系统化的AI开发指南。“图书馆开放AI-Demo工作坊”的案例实践表明,图书馆员能够充分利用其专业知识优势,结合AI工具与提示词工程,开发出满足实际需求的创新解决方案。这一探索不仅有助于解决图书馆业务中的长尾需求,更展现了技术民主化时代图书馆员角色的新价值。 展开更多
关键词 技术民主化 低代码 大语言模型 应用开发 AI应用
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自闭症与染色质三维结构关系的研究进展
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作者 高海明 张媛媛 何蓉 《生物技术进展》 2025年第3期418-425,共8页
自闭症谱系障碍(autism spectrum disorder,ASD)是一种发病率在1%~2%的复杂神经系统疾病,其发病具有显著的遗传异质性。三维基因组学研究揭示了染色质空间拓扑结构的动态调控在ASD病理机制中的核心作用,尤其是拓扑关联结构域(topologica... 自闭症谱系障碍(autism spectrum disorder,ASD)是一种发病率在1%~2%的复杂神经系统疾病,其发病具有显著的遗传异质性。三维基因组学研究揭示了染色质空间拓扑结构的动态调控在ASD病理机制中的核心作用,尤其是拓扑关联结构域(topologically associated domains,TADs)的边界破坏或内部互作紊乱,可通过表观遗传重编程导致神经发育关键基因的时空表达失调。然而,目前对ASD相关三维基因组变异尚未得到系统性解析以及现有临床诊断体系缺乏对三维基因组标志物的整合应用。系统综述了TADs介导的染色质区室化调控在ASD神经发展中的分子机制,总结了高通量染色体构象捕获技术(high-throughput chromosome conformation capture,Hi-C)及其衍生方法在ASD三维表观基因组图谱构建中的技术创新,以期为ASD的早期分子分型及靶向治疗提供理论支撑和技术范式。 展开更多
关键词 染色质三维结构 自闭症谱系障碍 拓扑关联结构域 非编码区变异 Hi-C技术
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科学技术组织机构分类及机构编码标准化研究
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作者 许红霞 邱盼盼 王宇鹏 《中国标准化》 2025年第18期59-64,共6页
科学技术组织作为科技活动、科技资源、科技成果的主要承载体,是国家创新能力和竞争力提升的关键。为了推动科技组织数据的标准化和规范化,基于线分类法提出了科技组织分类体系,覆盖科协系统的组织机构,以及国内外其他组织机构的类别划... 科学技术组织作为科技活动、科技资源、科技成果的主要承载体,是国家创新能力和竞争力提升的关键。为了推动科技组织数据的标准化和规范化,基于线分类法提出了科技组织分类体系,覆盖科协系统的组织机构,以及国内外其他组织机构的类别划分,并且制定了科技组织机构代码的编码规则,从基本信息、管理信息和业务信息3个维度分析了科技组织的属性特征,为科技组织信息的标准化建立了一套从分类、编码到元数据定义的完整数字化框架。 展开更多
关键词 组织机构分类 科学技术组织 机构编码规则 组织元数据标准
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