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Clinical Significance of Real-Time Two- Dimensional Shear Wave Elastography (SWE) in Assessing Liver Parenchymal Stiffness for Predicting the Severity of Non-Alcoholic Fatty Liver Disease (NAFLD)
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作者 Jiayi Ma Qinyi Qian 《Journal of Clinical and Nursing Research》 2025年第9期250-257,共8页
Objective:To evaluate the value of real-time two-dimensional shear wave elastography(SWE)in predicting liver parenchymal stiffness in non-alcoholic fatty liver disease(NAFLD).Methods:A total of 200 NAFLD patients(70 i... Objective:To evaluate the value of real-time two-dimensional shear wave elastography(SWE)in predicting liver parenchymal stiffness in non-alcoholic fatty liver disease(NAFLD).Methods:A total of 200 NAFLD patients(70 in the mild group,70 in the moderate group,and 60 in the severe group)and 60 healthy individuals(control group)who visited the hospital from December 2023 to December 2024 underwent real-time two-dimensional SWE examinations.Results:Except for high-density lipoprotein,comparisons of body mass index and biochemical indicators showed that the severe group>moderate group>mild group>control group,with P<0.05.Comparisons of liver stiffness values also showed that the severe group>moderate group>mild group>control group,with P<0.05.Pearson correlation analysis revealed a positive correlation between liver stiffness values and body mass index,triglycerides,total cholesterol,low-density lipoprotein,fasting blood glucose,and glycosylated hemoglobin.Analysis of the ROC curve indicated that the AUC,standard deviation,and P-value for liver stiffness values were 0.901,0.025,and 0.01,respectively,suggesting that liver stiffness values can predict the severity of NAFLD.Conclusion:The real-time two-dimensional shear wave elastography(SWE)technique for diagnosing NAFLD can differentiate between NAFLD patients and healthy individuals,as well as determine liver parenchymal stiffness,thereby assisting physicians in quantifying the degree of fatty liver. 展开更多
关键词 NAFLD Liver parenchymal stiffness Real-time two-dimensional SWE technique Predictive value
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Stiffness evaluation and experimental test of a novel redundantly actuated parallel machining robot
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作者 Hanliang Fang Jian Wang +2 位作者 Shuyi Ge Fufu Yang Jun Zhang 《Chinese Journal of Mechanical Engineering》 2026年第1期413-422,共10页
Parallel machining robot is a new type of robotized equipment for high-efficiency machining structural com-ponents with complex geometries.Terminal rigidity is of great importance index for such type of equipment,whic... Parallel machining robot is a new type of robotized equipment for high-efficiency machining structural com-ponents with complex geometries.Terminal rigidity is of great importance index for such type of equipment,which affects their load capacity and working accuracy.Before a parallel machining robot can be used for heavy-load and high-efficiency machining,its terminal rigidity should be evaluated systematically.The present study is to quantitatively reveal the stiffness properties of a previously invented Z4 redundantly actuated parallel ma-chining robot(RAPMR).For this purpose,two critical issues,i.e.,stiffness modelling and index construction,are clarified to carry out stiffness evaluation of the Z4 RAPMR.Firstly,drawing on the screw theory,a semi-analytic stiffness model of the proposed RAPMR is established at a component level.Secondly,a set of virtual work-based stiffness indices is constructed to evaluate the terminal rigidity of parallel robots.Those indices have a consistent physical unit in describing linear and angular terminal rigidity.With these indices,the local and the global stiffness performance of the Z4 RAPMR are predicted.Thirdly,a laboratory prototype of the proposed RAPMR is fabricated.And the experimental test is performed to verify the correctness of the established stiffness model.The present work is expected to provide fundamental information for further light-weight design and rigidity enhancement. 展开更多
关键词 Parallel machining robot Redundantly actuated Terminal rigidity stiffness model Experimental test
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CDA-Net:Cross dimensional attention network for wetland bird detection
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作者 Jia'nan Lv Changchun Zhang +1 位作者 Jiangjian Xie Junguo Zhang 《Avian Research》 2026年第1期216-227,共12页
Monitoring waterbirds is vital for evaluating the ecological health of wetlands,and object detection offers an automated solution for identifying birds in monitoring imagery.However,conventional detection methods ofte... Monitoring waterbirds is vital for evaluating the ecological health of wetlands,and object detection offers an automated solution for identifying birds in monitoring imagery.However,conventional detection methods often overlook the multi-scale nature of bird targets,limiting their ability to capture rich contextual information across different scales.To address this,we propose a cross-dimensional attention network(CDA-Net)for bird detection that integrates spatial and channel information to improve species recognition.The proposed CDA-Net partitions feature maps into multiple channel wise sub-features.Spatial and channel attention are applied to each subfeature,and the resulting features are fused using the Hadamard product.The fused features are then forwarded to the detection head to generate the final detection results.This approach effectively captures and integrates information across spatial and channel dimensions.Experiments on our self-constructed Nanhai Wetland Waterbird Dataset and the public CUB-200-2011 dataset yield precision scores of 91.32%and 81.99%,respectively,outperforming existing methods.Our approach effectively handles scale variation in bird detection and provides a valuable tool for advancing automated wetland waterbird monitoring. 展开更多
关键词 Bird detection Channel and spatial attention Cross dimensional network Feature integration Multi sizes object
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Cooperative Metaheuristics with Dynamic Dimension Reduction for High-Dimensional Optimization Problems
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作者 Junxiang Li Zhipeng Dong +2 位作者 Ben Han Jianqiao Chen Xinxin Zhang 《Computers, Materials & Continua》 2026年第1期1484-1502,共19页
Owing to their global search capabilities and gradient-free operation,metaheuristic algorithms are widely applied to a wide range of optimization problems.However,their computational demands become prohibitive when ta... Owing to their global search capabilities and gradient-free operation,metaheuristic algorithms are widely applied to a wide range of optimization problems.However,their computational demands become prohibitive when tackling high-dimensional optimization challenges.To effectively address these challenges,this study introduces cooperative metaheuristics integrating dynamic dimension reduction(DR).Building upon particle swarm optimization(PSO)and differential evolution(DE),the proposed cooperative methods C-PSO and C-DE are developed.In the proposed methods,the modified principal components analysis(PCA)is utilized to reduce the dimension of design variables,thereby decreasing computational costs.The dynamic DR strategy implements periodic execution of modified PCA after a fixed number of iterations,resulting in the important dimensions being dynamically identified.Compared with the static one,the dynamic DR strategy can achieve precise identification of important dimensions,thereby enabling accelerated convergence toward optimal solutions.Furthermore,the influence of cumulative contribution rate thresholds on optimization problems with different dimensions is investigated.Metaheuristic algorithms(PSO,DE)and cooperative metaheuristics(C-PSO,C-DE)are examined by 15 benchmark functions and two engineering design problems(speed reducer and composite pressure vessel).Comparative results demonstrate that the cooperative methods achieve significantly superior performance compared to standard methods in both solution accuracy and computational efficiency.Compared to standard metaheuristic algorithms,cooperative metaheuristics achieve a reduction in computational cost of at least 40%.The cooperative metaheuristics can be effectively used to tackle both high-dimensional unconstrained and constrained optimization problems. 展开更多
关键词 dimension reduction modified principal components analysis high-dimensional optimization problems cooperative metaheuristics metaheuristic algorithms
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On a broadband vibration isolator with tunable stiffness:from quasi-zero-stiffness to zero-stiffness behavior
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作者 N.A.SAEED Lei HOU +3 位作者 Haiming YI A.A.SHUKUR S.M.ALAMRY S.M.EL-SHOURBAGY 《Applied Mathematics and Mechanics(English Edition)》 2026年第2期255-282,共28页
A novel vibration isolation system designed for superior performance in low-frequency environments is proposed in this work.The isolator is based on a unique hexagonal arrangement of linear springs,allowing for an adj... A novel vibration isolation system designed for superior performance in low-frequency environments is proposed in this work.The isolator is based on a unique hexagonal arrangement of linear springs,allowing for an adjustable geometric configuration via the initial inclination angle.Based on the principle of Lagrangian mechanics,the equation of motion governing the structural dynamics is rigorously derived.The system is modeled as a strongly nonlinear single-degree-of-freedom dynamical system,loaded with a normalized payload and subject to harmonic base excitation.To analyze the steady-state response,the harmonic balance method is employed,providing accurate predictions of the payload's vibration amplitude and displacement transmissibility as functions of both the base excitation amplitude and frequency.The analysis reveals a direct relationship between the isolator's geometric and stiffness parameters and its load-bearing capacity,leading to the identification of three distinct operational regimes.Depending on the unloaded initial inclination angle,the equivalent stiffness ratio,and the payload design configuration,the system can exhibit one of three vibration isolation modes:(i)the quasizero stiffness(QZS)isolation mode,(ii)the zero linear stiffness with controllable nonlinear stiffness,and(iii)the full-band perfect zero stiffness.The vibration isolation performance of the proposed structure is thoroughly discussed for all three oscillation modes in terms of frequency response curves,displacement transmissibility,and time-domain responses.The key novel finding is that this structure can operate as a full-band,high-performance vibration isolator when the initial inclination angle is designed to be a right angle,enabling full isolation of the maximum possible payload.Moreover,the analytical results and numerical simulations demonstrate that the isolator's displacement transmissibility T with the unit dB tends to-∞as the air-damping coefficient approaches zero,enabling ideal vibration isolation across the entire excitation frequency range.These analytical insights are validated through comprehensive numerical simulations,which show excellent agreement with the theoretical predictions. 展开更多
关键词 nonlinear vibration isolation quasi-zero stiffness(QZS)structure full-band vibration isolator harmonic balance method displacement transmissibility
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Hydrogenation and Doping Induced One-Dimensional High-Temperature Superconductivity in carbon Nanotube
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作者 Hao Wang Bao-Tong Liu +5 位作者 Shu-Xiang Qiao Na Jiao Guili Yu Ping Zhang C.S.Ting Hong-Yan Lu 《Chinese Physics Letters》 2026年第1期198-210,共13页
In recent years,the research on superconductivity in one-dimensional(1D)materials has been attracting increasing attention due to its potential applications in low-dimensional nanodevices.However,the critical temperat... In recent years,the research on superconductivity in one-dimensional(1D)materials has been attracting increasing attention due to its potential applications in low-dimensional nanodevices.However,the critical temperature(T_(c))of 1D superconductors is low.In this work,we theoretically investigate the possible high T_(c) superconductivity of(5,5)carbon nanotube(CNT).The pristine(5,5)CNT is a Dirac semimetal and can be modulated into a semiconductor by full hydrogenation.Interestingly,by further hole doping,it can be regulated into a metallic state with the sp^(3)-hybridized σ electrons metalized,and a giant Kohn anomaly appears in the optical phonons.The two factors together enhance the electron–phonon coupling,and lead to high-T_(c) superconductivity.When the hole doping concentration of hydrogenated-(5,5)CNT is 2.5 hole/cell,the calculated T_(c) is 82.3 K,exceeding the boiling point of liquid nitrogen.Therefore,the predicted hole-doped hydrogenated-(5,5)CNT provides a new platform for 1D high-T_(c) superconductivity and may have potential applications in 1D nanodevices. 展开更多
关键词 high temperature superconductivity DOPING critical temperature dirac semimetal one dimensional materials HYDROGENATION full hydrogenationinterestinglyby hole dopingit
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Erratum:Bone Regeneration Eff cacy and Applicability of Defect-Fitting 4D Scaffolds Based on Shape Conformity in Three-dimensional Curved Bone Defects
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作者 Min-Soo Ghim Se-Jin Jang +3 位作者 Eun-Yong Choi Meiling Quan Young-Yul Kim Young-Sam Cho 《Journal of Bionic Engineering》 2026年第1期550-550,共1页
The original online version of this article was revised:The layout update for Article 758 has impacted the page range in the published issue,but did not affect the scholarly content.To ensure consistency with the orig... The original online version of this article was revised:The layout update for Article 758 has impacted the page range in the published issue,but did not affect the scholarly content.To ensure consistency with the originally assigned pages(2595-2614),we will need to publish an erratum to correct the article and restore the original page range.The original article has been corrected. 展开更多
关键词 defect fitting D scaffolds layout update shape conformity three dimensional curved bone defects bone regeneration
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Three-dimensional patient-derived cell models represent an emerging frontier in the study of neurodegenerative diseases
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作者 Rachel J.Boyd Vasiliki Mahairaki 《Neural Regeneration Research》 2026年第6期2327-2328,共2页
Neurodegenerative disorders represent an increasingly pertinent public health crisis.As a greater proportion of the population ages,neurodegenerative disorders and other diseases of aging place undue burdens on patien... Neurodegenerative disorders represent an increasingly pertinent public health crisis.As a greater proportion of the population ages,neurodegenerative disorders and other diseases of aging place undue burdens on patients,caregivers,and healthcare workers.Alzheimer’s disease(AD)and Parkinson’s disease represent the two most common neurodegenerative disorders in the population,affecting over 65 million people,worldwide. 展开更多
关键词 Alzheimer s disease public health crisis neurodegenerative diseases neurodegenerative disorders parkinson s disease aging three dimensional patient derived cell models
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Enabling Intrinsic Antiferroelectricity in Two-dimensional NbOCl_(2):Molecular Dynamics Simulations based on Deep Learning Interatomic Potential
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作者 Jiawei Mao Yinglu Jia +2 位作者 Gaoyang Gou Shi Liu Xiao Cheng Zeng 《Chinese Physics Letters》 2026年第1期156-178,共23页
Compared to the well-studied two-dimensional(2D)ferroelectricity,the appearance of 2D antiferroelectricity is much rarer,where local dipoles from the nonequivalent sublattices within 2D monolayers are oppositely orien... Compared to the well-studied two-dimensional(2D)ferroelectricity,the appearance of 2D antiferroelectricity is much rarer,where local dipoles from the nonequivalent sublattices within 2D monolayers are oppositely oriented.Using NbOCl_(2) monolayer with competing ferroelectric(FE)and antiferroelectric(AFE)phases as a 2D material platform,we demonstrate the emergence of intrinsic antiferroelectricity in NbOCl_(2) monolayer under experimentally accessible shear strain,along with new functionality associated with electric field-induced AFE-to-FE phase transition.Specifically,the complex configuration space accommodating FE and AFE phases,polarization switching kinetics,and finite temperature thermodynamic properties of 2D NbOCl_(2) are all accurately predicted by large-scale molecular dynamics simulations based on deep learning interatomic potential model.Moreover,room temperature stable antiferroelectricity with low polarization switching barrier and one-dimensional collinear polarization arrangement is predicted in shear-deformed NbOCl_(2) monolayer.The transition from AFE to FE phase in 2D NbOCl_(2) can be triggered by a low critical electric field,leading to a double polarization–electric(P–E)loop with small hysteresis.A new type of optoelectronic device composed of AFE-NbOCl_(2) is proposed,enabling electric“writing”and nonlinear optical“reading”logical operation with fast operation speed and low power consumption. 展开更多
关键词 d monolayers local dipoles nonequivalent sublattices intrinsic antiferroelectricity two dimensional nbocl d antiferroelectricity experimentally accessible shear strainalong molecular dynamics simulations
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Theoretical prediction of stiffness and strength of three-dimensional and four-directional braided composites
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作者 李典森 卢子兴 卢文书 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2008年第2期163-170,共8页
Based on unit cell model, the 3D 4-directional braided composites can be simplified as unidirectional composites with different local axial coordinate system and the compliance matrix of unidirectional composites can ... Based on unit cell model, the 3D 4-directional braided composites can be simplified as unidirectional composites with different local axial coordinate system and the compliance matrix of unidirectional composites can be defined utilizing the bridge model. The total stiffness matrix of braided composites can be obtained by the volume average stiffness of unidirectional composites with different local axial coordinate system and the engineering elastic constants of braided composites were computed further. Based on the iso-strain assumption and the bridge model, the stress distribution of fiber bundle and matrix of different unidirectional composites can be determined and the tensile strength of 3D 4-directional braided composites was predicted by means of the Hoffman's failure criterion for the fiber bundle and Mises' failure criterion for the matrix. 展开更多
关键词 3D braiding STRENGTH stiffness mechanical properties composites
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Matrix stiffness regulates nucleus pulposus cell glycolysis by MRTF-A-dependent mechanotransduction 被引量:2
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作者 Haoran Xu Kang Wei +10 位作者 Jinhao Ni Xiaofeng Deng Yuexing Wang Taiyang Xiang Fanglong Song Qianliang Wang Yanping Niu Fengxian Jiang Jun Wang Lei Sheng Jun Dai 《Bone Research》 2025年第2期476-489,共14页
Increased matrix stiffness of nucleus pulposus(NP)tissue is a main feature of intervertebral disc degeneration(IVDD)and affects various functions of nucleus pulposus cells(NPCs).Glycolysis is the main energy source fo... Increased matrix stiffness of nucleus pulposus(NP)tissue is a main feature of intervertebral disc degeneration(IVDD)and affects various functions of nucleus pulposus cells(NPCs).Glycolysis is the main energy source for NPC survival,but the effects and underlying mechanisms of increased extracellular matrix(ECM)stiffness on NPC glycolysis remain unknown.In this study,hydrogels with different stiffness were established to mimic the mechanical environment of NPCs.Notably,increased matrix stiffness in degenerated NP tissues from IVDD patients was accompanied with impaired glycolysis,and NPCs cultured on rigid substrates exhibited a reduction in glycolysis. 展开更多
关键词 MECHANOTRANSDUCTION nucleus pulposus cells npcs glycolysis increased matrix stiffness nucleus pulposus np tissue nucleus pulposus cells matrix stiffness intervertebral disc degeneration ivdd GLYCOLYSIS
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Programmable Quasi-Zero-Stiffness Metamaterials 被引量:1
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作者 Wenlong Liu Sen Yan +5 位作者 Zhiqiang Meng Lingling Wu Yong Xu Jie Chen Jingbo Sun Ji Zhou 《Engineering》 2025年第4期160-167,共8页
Quasi-zero-stiffness(QZS)metamaterials have attracted significant interest for application in low-frequency vibration isolation.However,previous work has been limited by the design mechanism of QZS metamaterials,as it... Quasi-zero-stiffness(QZS)metamaterials have attracted significant interest for application in low-frequency vibration isolation.However,previous work has been limited by the design mechanism of QZS metamaterials,as it is still difficult to achieve a simplified structure suitable for practical engineering applications.Here,we introduce a class of programmable QZS metamaterials and a novel design mechanism that address this long-standing difficulty.The proposed QZS metamaterials are formed by an array of representative unit cells(RUCs)with the expected QZS features,where the QZS features of the RUC are tailored by means of a structural bionic mechanism.In our experiments,we validate the QZS features exhibited by the RUCs,the programmable QZS behavior,and the potential promising applications of these programmable QZS metamaterials in low-frequency vibration isolation.The obtained results could inspire a new class of programmable QZS metamaterials for low-frequency vibration isolation in current and future mechanical and other engineering applications. 展开更多
关键词 Quasi-zero stiffness METAMATERIALS Vibration isolation Bionic mechanism
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Revisiting the normal stiffness–permeability relations for shale fractures under true triaxial stress 被引量:1
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作者 Fudong Li Derek Elsworth +6 位作者 Xia-Ting Feng Tianyu Chen Jun Zhao Yingchun Li Jianyu Zhang Qiong Wu Guanglei Cui 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第8期5001-5017,共17页
Understanding the relationship between normal stiffness and permeability in rock fractures under high and true-triaxial in situ stress conditions is critical to assess hydro-mechanical coupling in the Earth's crus... Understanding the relationship between normal stiffness and permeability in rock fractures under high and true-triaxial in situ stress conditions is critical to assess hydro-mechanical coupling in the Earth's crust.Previous data on stiffness–permeability relations are measured under uniaxial stress states as well as under normal stress.However,many projects involve faulted formations with complex three-dimensional(3D)stress states or significant changes to the original stress state.We rectified this by following the permeability evolution using a true-triaxial stress-permeability apparatus as well as independently applying a spectrum of triaxial stresses from low to high.The relationship between permeability and fracture normal stiffness was quantified using constraints based on the principle of virtual work.The impacts of fracture-lateral and fracture-normal stresses on permeability and normal stiffness evolution were measured.It was found that permeability decreases with increasing fracture-lateral and fracture-normal stresses as a result of Poisson confinement,independent of the orientation of the fracture relative to the stresses.The lateral stresses dominated the evolution of normal stiffness at lower normal stresses(σ_(3)=10 MPa)and played a supplementary role at higher normal stresses(σ_(3)>10 MPa).Moreover,correlations between the evolution of permeability and normal stiffness were extended beyond the low-stiffness,high-permeability region to the high-stiffness,low-permeability region under high fracture-lateral stresses(10–80 MPa)with fracture-normal stress(10–50 MPa)conditions.Again,high lateral stresses further confined the fracture and therefore reduced permeability and increased normal stiffness,which exceeded the previous reported stiffness under no lateral stress conditions.This process enabled us to identify a fundamental change in the flow regime from multi-channel to isolated channelized flow.These results provide important characterizations of fracture permeability in the deep crust,including recovery from deep shale-gas reservoirs. 展开更多
关键词 Fracture permeability Deformation Fracture normal stiffness True-triaxial stress Principle of virtual work
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Shear behaviors of intermittent joints subjected to shearing cycles under constant normal stiffness conditions:Effects of loading parameters 被引量:1
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作者 Bin Wang Yujing Jiang +1 位作者 Qiangyong Zhang Hongbin Chen 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第5期2695-2712,共18页
A conceptual model of intermittent joints is introduced to the cyclic shear test in the laboratory to explore the effects of loading parameters on its shear behavior under cyclic shear loading.The results show that th... A conceptual model of intermittent joints is introduced to the cyclic shear test in the laboratory to explore the effects of loading parameters on its shear behavior under cyclic shear loading.The results show that the loading parameters(initial normal stress,normal stiffness,and shear velocity)determine propagation paths of the wing and secondary cracks in rock bridges during the initial shear cycle,creating different morphologies of macroscopic step-path rupture surfaces and asperities on them.The differences in stress state and rupture surface induce different cyclic shear responses.It shows that high initial normal stress accelerates asperity degradation,raises shear resistance,and promotes compression of intermittent joints.In addition,high normal stiffness provides higher normal stress and shear resistance during the initial cycles and inhibits the dilation and compression of intermittent joints.High shear velocity results in a higher shear resistance,greater dilation,and greater compression.Finally,shear strength is most sensitive to initial normal stress,followed by shear velocity and normal stiffness.Moreover,average dilation angle is most sensitive to initial normal stress,followed by normal stiffness and shear velocity.During the shear cycles,frictional coefficient is affected by asperity degradation,backfilling of rock debris,and frictional area,exhibiting a non-monotonic behavior. 展开更多
关键词 Intermittent joint Cyclic shear Loading parameter Constant normal stiffness(CNS)
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Stiffness-tunable biomaterials provide a good extracellular matrix environment for axon growth and regeneration
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作者 Ronglin Han Lanxin Luo +4 位作者 Caiyan Wei Yaru Qiao Jiming Xie Xianchao Pan Juan Xing 《Neural Regeneration Research》 SCIE CAS 2025年第5期1364-1376,共13页
Neuronal growth, extension, branching, and formation of neural networks are markedly influenced by the extracellular matrix—a complex network composed of proteins and carbohydrates secreted by cells. In addition to p... Neuronal growth, extension, branching, and formation of neural networks are markedly influenced by the extracellular matrix—a complex network composed of proteins and carbohydrates secreted by cells. In addition to providing physical support for cells, the extracellular matrix also conveys critical mechanical stiffness cues. During the development of the nervous system, extracellular matrix stiffness plays a central role in guiding neuronal growth, particularly in the context of axonal extension, which is crucial for the formation of neural networks. In neural tissue engineering, manipulation of biomaterial stiffness is a promising strategy to provide a permissive environment for the repair and regeneration of injured nervous tissue. Recent research has fine-tuned synthetic biomaterials to fabricate scaffolds that closely replicate the stiffness profiles observed in the nervous system. In this review, we highlight the molecular mechanisms by which extracellular matrix stiffness regulates axonal growth and regeneration. We highlight the progress made in the development of stiffness-tunable biomaterials to emulate in vivo extracellular matrix environments, with an emphasis on their application in neural repair and regeneration, along with a discussion of the current limitations and future prospects. The exploration and optimization of the stiffness-tunable biomaterials has the potential to markedly advance the development of neural tissue engineering. 展开更多
关键词 ALGINATE axon growth BIOMATERIALS extracellular matrix neural repair neurons NEUROREGENERATION POLYACRYLAMIDE POLYDIMETHYLSILOXANE stiffness
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Variable stiffness design optimization of fiber-reinforced composite laminates with regular and irregular holes considering fiber continuity for additive manufacturing 被引量:1
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作者 Yi LIU Zunyi DUAN +6 位作者 Chunping ZHOU Yuan SI Chenxi GUAN Yi XIONG Bin XU Jun YAN Jihong ZHU 《Chinese Journal of Aeronautics》 2025年第3期334-354,共21页
Fiber-reinforced composites are an ideal material for the lightweight design of aerospace structures. Especially in recent years, with the rapid development of composite additive manufacturing technology, the design o... Fiber-reinforced composites are an ideal material for the lightweight design of aerospace structures. Especially in recent years, with the rapid development of composite additive manufacturing technology, the design optimization of variable stiffness of fiber-reinforced composite laminates has attracted widespread attention from scholars and industry. In these aerospace composite structures, numerous cutout panels and shells serve as access points for maintaining electrical, fuel, and hydraulic systems. The traditional fiber-reinforced composite laminate subtractive drilling manufacturing inevitably faces the problems of interlayer delamination, fiber fracture, and burr of the laminate. Continuous fiber additive manufacturing technology offers the potential for integrated design optimization and manufacturing with high structural performance. Considering the integration of design and manufacturability in continuous fiber additive manufacturing, the paper proposes linear and nonlinear filtering strategies based on the Normal Distribution Fiber Optimization (NDFO) material interpolation scheme to overcome the challenge of discrete fiber optimization results, which are difficult to apply directly to continuous fiber additive manufacturing. With minimizing structural compliance as the objective function, the proposed approach provides a strategy to achieve continuity of discrete fiber paths in the variable stiffness design optimization of composite laminates with regular and irregular holes. In the variable stiffness design optimization model, the number of candidate fiber laying angles in the NDFO material interpolation scheme is considered as design variable. The sensitivity information of structural compliance with respect to the number of candidate fiber laying angles is obtained using the analytical sensitivity analysis method. Based on the proposed variable stiffness design optimization method for complex perforated composite laminates, the numerical examples consider the variable stiffness design optimization of typical non-perforated and perforated composite laminates with circular, square, and irregular holes, and systematically discuss the number of candidate discrete fiber laying angles, discrete fiber continuous filtering strategies, and filter radius on structural compliance, continuity, and manufacturability. The optimized discrete fiber angles of variable stiffness laminates are converted into continuous fiber laying paths using a streamlined process for continuous fiber additive manufacturing. Meanwhile, the optimized non-perforated and perforated MBB beams after discrete fiber continuous treatment, are manufactured using continuous fiber co-extrusion additive manufacturing technology to verify the effectiveness of the variable stiffness fiber optimization framework proposed in this paper. 展开更多
关键词 Variable stiffness composite laminates Discrete material interpolation scheme Normal distribution fiber optimization Discrete fiber continuous filtering strategy Additive manufacturing of composite laminates
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Stiffness gradient sensitivity analysis method for evaluating the vibration reduction effect of complex variable-stiffness systems
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作者 Xingchi CAO Xin FANG Dianlong YU 《Applied Mathematics and Mechanics(English Edition)》 2025年第11期2055-2074,共20页
An analytical method is proposed with the “stiffness gradient of the response” as a sensitivity metric, and the relationships between the vibration responses and stiffness changes are established. First, a 2-degree-... An analytical method is proposed with the “stiffness gradient of the response” as a sensitivity metric, and the relationships between the vibration responses and stiffness changes are established. First, a 2-degree-of-freedom (DOF) system is used as an example to propose a stiffness gradient-based evaluation method, taking the effective control bandwidth ratio as a metric of effectiveness. The results show that there is an optimal mass ratio in both variable mass and variable stiffness cases. Then, a typical 16-DOF system is used to investigate the frequency domain characteristics of the stiffness gradient values in the complex system. The distributions of stiffness gradient values show multiple peak intervals corresponding to the sensitive regions for vibration control. By assigning random mass parameters, a significant exponential decay relationship between the subsystem’s mass and effective control is identified, emphasizing the importance of the optimal mass ratio. The finite-element simulation results of solid plate models with springs and oscillators further validate the theoretical results. In short, the gradient value of stiffness effectively quantifies the effects of subsystems on vibration control, providing an analytical tool for active control in complex systems. The identified exponential decay relationship offers meaningful guidance for implementation strategies. 展开更多
关键词 stiffness gradient sensitivity optimal mass stiffness regulation vibration reduction
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Assessment of liver stiffness measurement-related markers in predicting liver-related events in viral cirrhosis with clinically significant portal hypertension
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作者 Yan-Qiu Li Yong-Qi Li +4 位作者 Jin-Ze Li Bing-Bing Zhu Yu Lu Ying Feng Xian-Bo Wang 《World Journal of Hepatology》 2025年第8期257-271,共15页
BACKGROUND Clinically significant portal hypertension(CSPH)is a crucial prognostic deter-minant for liver-related events(LREs)in patients with compensated viral cir-rhosis.Liver stiffness measurement(LSM)-related mark... BACKGROUND Clinically significant portal hypertension(CSPH)is a crucial prognostic deter-minant for liver-related events(LREs)in patients with compensated viral cir-rhosis.Liver stiffness measurement(LSM)-related markers may help to predict the risk of LREs.AIM To evaluate the value of LSM and its composite biomarkers[LSM-platelet ratio(LPR),LSM-albumin ratio(LAR)]in predicting LREs.METHODS This study retrospectively enrolled compensated viral cirrhosis patients with CSPH.The Cox regression model was employed to examine the prediction of LSM,LPR,and LAR for LREs.The model performance was assessed through receiver operating characteristic,decision curve,and time-dependent area under the curve analysis.The Kaplan-Meier curve was used to evaluate the cumulative incidence of LREs,and further stratified analysis of different LREs was per-formed.RESULTS A total of 598 patients were included,and 319 patients(53.3%)developed LREs during follow-up.Multivariate proportional hazards modeling demonstrated that LSM,LPR,and LAR were independent predictors of LREs.LPR had better performance in predicting LREs than LAR and LSM(area under the curve=0.780,0.727,0.683,respectively,all P<0.05).The cumulative incidence of LREs in the high-risk group were significantly higher than that in the low-risk group(P<0.001).Among the different LREs,LPR was superior to LSM and LAR in predicting liver decompensation,while the difference in predicting hepatocellular carcinoma and liver-related death was relatively small.CONCLUSION LPR is superior to LSM and LAR in predicting LREs in compensated viral cirrhosis patients with CSPH,especially in predicting liver decompensation. 展开更多
关键词 Liver stiffness measurement Liver stiffness measurement-platelet ratio Liver stiffness measurement-albumin ratio Liver-related events Clinically significant portal hypertension Viral cirrhosis
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A novel quasi-zero stiffness isolator with designable stiffness using cam-roller-spring-rod mechanism
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作者 Yonglei Zhang Hao Wen +1 位作者 Haiyan Hu Dongping Jin 《Acta Mechanica Sinica》 2025年第6期158-170,共13页
Quasi-zero stiffness(QZS)isolators have received considerable attention over the past years due to their outstanding vibration isolation performance in low-frequency bands.However,traditional mechanisms for achieving ... Quasi-zero stiffness(QZS)isolators have received considerable attention over the past years due to their outstanding vibration isolation performance in low-frequency bands.However,traditional mechanisms for achieving QZS suffer from low stiffness regions and significant nonlinear restoring forces with hardening characteristics,often struggling to withstand excitations with high amplitude.This paper presents a novel QZS vibration isolator that utilizes a more compact spring-rod mechanism(SRM)to provide primary negative stiffness.The nonlinearity of SRM is adjustable via altering the raceway of its spring-rod end,along with the compensatory force provided by the cam-roller mechanism so as to avoid complex nonlinear behaviors.The absolute zero stiffness can be achieved by a well-designed raceway curve with a concise mathematical expression.The nonlinear stiffness with softening properties can also be achieved by parameter adjustment.The study begins with the forcedisplacement relationship of the integrated mechanism first,followed by the design theory of the cam profile.The dynamic response and absolute displacement transmissibility of the isolation system are obtained based on the harmonic balance method.The experimental results show that the proposed vibration isolator maintains relatively low-dynamic stiffness even under non-ideal conditions,and exhibits enhanced vibration isolation performance compared to the corresponding linear isolator. 展开更多
关键词 Vibration isolation Quasi-zero stiffness Spring-rod mechanism Cam-roller mechanism Absolute zero stiffness
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Discrete element analyses of stiffness distribution of gap-graded soils with particle property disparity
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作者 Deyun Liu Mengting Wang Ci Wang 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第4期2603-2618,共16页
Utilizing the Discrete Element Method,this research studied the stiffness distribution of gap-graded soils by modifying the conventional static method.By acknowledging the inherent particle property disparity between ... Utilizing the Discrete Element Method,this research studied the stiffness distribution of gap-graded soils by modifying the conventional static method.By acknowledging the inherent particle property disparity between coarser and finer particles,this research differentiates the stiffness distribution of gap-graded soils from the perspective of contact and particle types.Results indicate that particle property disparity significantly influence the small-strain stiffness characteristics,consequently altering the overall stiffness distribution in gap-graded soil specimens.Specifically,with the equivalent coarser particle property,an increase in particle Young's modulus of finer particles results in an augmentation of small-strain stiffness values,alongside an increased stiffness distribution contribution from finer particles.Nevertheless,this study reveals that even with a higher particle Young's modulus of finer particles,the proportion of small-strain stiffness transferred by finer particles remains consistently lower than their volume fraction.Furthermore,the proportion of stiffness transferred by finer particles may fall below their contribution to stress transmission.This investigation accentuates the subtle yet significant effects of particle property variations on small strain stiffness and its subsequent distribution,providing a foundation for advancing the significance of particle property disparities in evaluating soil responses. 展开更多
关键词 Discrete element method Particle property disparity Gap-graded soils stiffness distribution Small-strain stiffness
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