This paper describes a simple method of generating concentration gradients with linear and parabolic profiles by using a Christmas tree-shaped microfluidic network.The microfluidic gradient generator consists of two p...This paper describes a simple method of generating concentration gradients with linear and parabolic profiles by using a Christmas tree-shaped microfluidic network.The microfluidic gradient generator consists of two parts：a Christmas tree-shaped network for gradient generation and a broad microchannel for detection.A two-dimensional model was built to analyze the flow field and the mass transfer in the microfluidic network.The simulating results show that a series of linear and parabolic gradient profiles were generated via adjusting relative flow rate ratios of the two source solutions（R_L^2≥0.995 and _PR^2≥0.999）,which could match well with the experimental results（R_L^2≥0.987 and _PR^2≥0.996）.The proposed method is promising for the generation of linear and parabolic concentration gradient profiles,with the potential in chemical and biological applications such as combinatorial chemistry synthesis,stem cell differentiation or cytotoxicity assays.展开更多
This paper lbcuses on the main characteristics of a tree-shaped timber structural system or simply tree-shaped. One of them is the complexity of its steel connections, responsible for the joint of bar elements, compou...This paper lbcuses on the main characteristics of a tree-shaped timber structural system or simply tree-shaped. One of them is the complexity of its steel connections, responsible for the joint of bar elements, compounding a complex structural system, which requires the application of the CYPECAD software version 2007 to solve the calculations problems. Its efficiency was confirmed by a variety of laboratory tests carried out with the whole structure. The tree-shaped is a timber structure that can be used in a large number of destinations, including residences, malls, sheds, hangars, etc.. Originally, it was conceived based on the well-known masterpiece ＂Sagrada Familia＂, whose author was Architect Antoni Gaudi I Cornet （1852-1926） in Barcelona/Spain. It was designed at the end of 19th century and its construction is still not finished. Gaudi inverted the logical order of the gothic concepts, i.e., light weights below and heavy weights above. Based on this concept, he always had in mind the figure of a tree in nature. The tree-shaped follows the same idea, using timber pieces connected by steel plates. Theoretical and numerical analyses have shown its efficiency and lightness for use in timber structures.展开更多
A transient flow model of tree-shaped fractal reservoirs is built by embedding a fracture network simulated by a tree-shaped fractal network into a matrix system. The model can be solved using the Laplace conversion m...A transient flow model of tree-shaped fractal reservoirs is built by embedding a fracture network simulated by a tree-shaped fractal network into a matrix system. The model can be solved using the Laplace conversion method. The dimensionless bottom hole pressure can be obtained using the Stehfest numerical inversion method. The bi-logarithmic type curves for the trce-shaped fractal reservoirs are thus obtained. The pressure transient responses under different fractal factors are discussed. The factors with a primary effect on the inter-porosity flow regime include the initial branch number N, the length ratio α, and the branch angle θ. The diameter ratio β has a significant effect on the fracture radial flow, the inter-porosity and the total system radial flow regimes. The total branch level M of the network mainly influences the total system radial flow regime. The model presented in this paper provides a new methodology for analyzing and predicting the pressure dynamic characteristics of naturally fractured reservoirs.展开更多
基金Supported by the National Natural Science Foundation of China(81372358,81527801,51303140,and 81602489)the Natural Science Foundation of Hubei Province(2014CFA029)+1 种基金the Colleges of Hubei Province Outstanding Youth Science and Technology Innovation Team(T201305)the Applied Foundational Research Program of Wuhan Municipal Science and Technology Bureau(2015060101010056)
文摘This paper describes a simple method of generating concentration gradients with linear and parabolic profiles by using a Christmas tree-shaped microfluidic network.The microfluidic gradient generator consists of two parts：a Christmas tree-shaped network for gradient generation and a broad microchannel for detection.A two-dimensional model was built to analyze the flow field and the mass transfer in the microfluidic network.The simulating results show that a series of linear and parabolic gradient profiles were generated via adjusting relative flow rate ratios of the two source solutions（R_L^2≥0.995 and _PR^2≥0.999）,which could match well with the experimental results（R_L^2≥0.987 and _PR^2≥0.996）.The proposed method is promising for the generation of linear and parabolic concentration gradient profiles,with the potential in chemical and biological applications such as combinatorial chemistry synthesis,stem cell differentiation or cytotoxicity assays.
文摘This paper lbcuses on the main characteristics of a tree-shaped timber structural system or simply tree-shaped. One of them is the complexity of its steel connections, responsible for the joint of bar elements, compounding a complex structural system, which requires the application of the CYPECAD software version 2007 to solve the calculations problems. Its efficiency was confirmed by a variety of laboratory tests carried out with the whole structure. The tree-shaped is a timber structure that can be used in a large number of destinations, including residences, malls, sheds, hangars, etc.. Originally, it was conceived based on the well-known masterpiece ＂Sagrada Familia＂, whose author was Architect Antoni Gaudi I Cornet （1852-1926） in Barcelona/Spain. It was designed at the end of 19th century and its construction is still not finished. Gaudi inverted the logical order of the gothic concepts, i.e., light weights below and heavy weights above. Based on this concept, he always had in mind the figure of a tree in nature. The tree-shaped follows the same idea, using timber pieces connected by steel plates. Theoretical and numerical analyses have shown its efficiency and lightness for use in timber structures.
基金supported by the National Science Fund for Distinguished Young Scholars of China(Grant No.51125019)supported by the 2014 Australia China National Gas Technology Partnership Fund Top Up Scholoarship
文摘A transient flow model of tree-shaped fractal reservoirs is built by embedding a fracture network simulated by a tree-shaped fractal network into a matrix system. The model can be solved using the Laplace conversion method. The dimensionless bottom hole pressure can be obtained using the Stehfest numerical inversion method. The bi-logarithmic type curves for the trce-shaped fractal reservoirs are thus obtained. The pressure transient responses under different fractal factors are discussed. The factors with a primary effect on the inter-porosity flow regime include the initial branch number N, the length ratio α, and the branch angle θ. The diameter ratio β has a significant effect on the fracture radial flow, the inter-porosity and the total system radial flow regimes. The total branch level M of the network mainly influences the total system radial flow regime. The model presented in this paper provides a new methodology for analyzing and predicting the pressure dynamic characteristics of naturally fractured reservoirs.
