Dairy wastewater,a kind of high concentration organic wastewater,is produced in large quantities and difficult to treat,and has a negative impact on the ecological environment.In this study,the source,composition,wate...Dairy wastewater,a kind of high concentration organic wastewater,is produced in large quantities and difficult to treat,and has a negative impact on the ecological environment.In this study,the source,composition,water quality characteristics of dairy wastewater and its impact on the ecological environment were analyzed,and the treatment methods of dairy wastewater at home and abroad in recent years were summarized,in order to provide a reference for the treatment of dairy wastewater.展开更多
Diabetic foot(DF)has emerged as one of the most common chronic consequences of diabetes mellitus,characterized by prolonged disease duration,high treatment costs,a poor prognosis,and a high disability rate.Diabetic hi...Diabetic foot(DF)has emerged as one of the most common chronic consequences of diabetes mellitus,characterized by prolonged disease duration,high treatment costs,a poor prognosis,and a high disability rate.Diabetic high-risk foot is the early stage of diabetic foot,the“disease prevention”of“treating no disease”,which provides a critical window for clinical prevention and treatment.Traditional Chinese medicine(TCM)has emphasized the importance of preventive health care since ancient times.External therapies such as acupuncture,massage,acupoint injection,foot bath fumigation,and moxibustion have the advantages of simplicity,low cost,precise efficacy,and fewer side effects in preventing and treating diabetic high-risk foot.The multidisciplinary synergistic model formed by TCM complementary therapies and modern medical treatments,such as nutritional,peripheral nerve,and blood glucose regulation,provides new ideas for establishing standardized prevention and treatment protocols.In this paper,studies related to TCM-related complementary therapies for diabetic high-risk feet are systematically reviewed.Current advances in external application in TCM were described to better understand its effectiveness and safety in elderly patients.展开更多
As the world’s largest palm oil producer,Indonesia significantly benefits from its palm oil industry but also faces serious environmental challenges from palm oil mill effluent(POME)-a high-strength wastewater contai...As the world’s largest palm oil producer,Indonesia significantly benefits from its palm oil industry but also faces serious environmental challenges from palm oil mill effluent(POME)-a high-strength wastewater containing substantial organic matter,nutrients,suspended solids,and various chemical compounds.Sustainable and effective wastewater treatment strategies are urgently needed to address this issue.This review presents a comprehensive analysis of existing POME treatment technologies,including anaerobic digestion(AD),advanced oxidation processes(AOPs),membrane filtration,adsorption,phytoremediation,and microalgae-based systems.Each method is examined in terms of treatment efficiency,operational feasibility,and potential for imple-mentation under Indonesian conditions.While advanced processes,such as AOPs and membrane filtration,achieve high pollutant removal,they are often limited by operational costs.In contrast,biological approaches,such as AD and phytoremediation,offer both environmental benefits and economic value through the recovery of biogas,biofertilizers,and biomass.This review highlights the potential for integrating wastewater purification with resource recovery and valorization,supporting a shift toward more circular and sustainable management of POME.The insights provided are intended to guide future research,inform policy decisions,and facilitate the industrial adoption of optimized treatment systems.展开更多
In their study,Han et al compared the efficacy of bevacizumab plus sindilizumab plus interventional therapy with that of lenvatinib plus sindilizumab plus interventional therapy for patients with intermediate and adva...In their study,Han et al compared the efficacy of bevacizumab plus sindilizumab plus interventional therapy with that of lenvatinib plus sindilizumab plus interventional therapy for patients with intermediate and advanced hepatocellular carcinoma.The triple therapy,which integrates interventional therapy,targeted therapy,and immunotherapy,has emerged as a promising research focus in the treatment of liver cancer.Consequently,it is of utmost significance to select an appropriate combination of interventional therapy,targeted therapy,and immunotherapy for patients suffering from intermediate and advanced liver cancer.展开更多
Silicon carbide fibers are considered ideal reinforcing materials for ceramic matrix composites due to their excellent mechanical properties and high-temperature performance.Different types of fibers necessitate indiv...Silicon carbide fibers are considered ideal reinforcing materials for ceramic matrix composites due to their excellent mechanical properties and high-temperature performance.Different types of fibers necessitate individual investigation due to variations in their composition and fabrication processes.This study presents a comprehensive investigation into evolution of the mechanical properties,surface microstructure,and composition of Shicolon-Ⅱ fibers subjected to argon heat treatment at temperatures ranging from 1300℃to 1700℃.The Shicolon-Ⅱ fibers are composed of small-sized β-SiC grains,SiC_(x)O_(y) amorphous phase,and a minor amount of graphite microcrystals.Following treatment in an argon atmosphere at 1300℃,the fibers maintain a monofilament tensile strength of 3.620 GPa,corresponding to a retention of 98.32%.This strength diminishes to 2.875 GPa,equating to a retention of 78.08%,after treatment at 1500℃.The reduction in mechanical properties of the fibers can be ascribed to the decomposition of the amorphous phase and the growth of β-SiC grains.Furthermore,creep resistance is an essential factor influencing the long-term performance of composite materials.After treatment at temperatures above 1400℃,the high-temperature creep resistance of the fibers is significantly enhanced due to growth of β-SiC grains.This study offers valuable theoretical insights into high-temperature applications of second-generation fibers,contributing to an enhanced understanding of their performance under extreme conditions.展开更多
The highly efficient electrochemical treatment technology for dye-polluted wastewater is one of hot research topics in industrial wastewater treatment.This study reported a three-dimensional electrochemical treatment ...The highly efficient electrochemical treatment technology for dye-polluted wastewater is one of hot research topics in industrial wastewater treatment.This study reported a three-dimensional electrochemical treatment process integrating graphite intercalation compound(GIC)adsorption,direct anodic oxidation,and·OH oxidation for decolourising Reactive Black 5(RB5)from aqueous solutions.The electrochemical process was optimised using the novel progressive central composite design-response surface methodology(CCD-NPRSM),hybrid artificial neural network-extreme gradient boosting(hybrid ANN-XGBoost),and classification and regression trees(CART).CCD-NPRSM and hybrid ANN-XGBoost were employed to minimise errors in evaluating the electrochemical process involving three manipulated operational parameters:current density,electrolysis(treatment)time,and initial dye concentration.The optimised decolourisation efficiencies were 99.30%,96.63%,and 99.14%for CCD-NPRSM,hybrid ANN-XGBoost,and CART,respectively,compared to the 98.46%RB5 removal rate observed experimentally under optimum conditions:approximately 20 mA/cm^(2) of current density,20 min of electrolysis time,and 65 mg/L of RB5.The optimised mineralisation efficiencies ranged between 89%and 92%for different models based on total organic carbon(TOC).Experimental studies confirmed that the predictive efficiency of optimised models ranked in the descending order of hybrid ANN-XGBoost,CCD-NPRSM,and CART.Model validation using analysis of variance(ANOVA)revealed that hybrid ANN-XGBoost had a mean squared error(MSE)and a coefficient of determination(R^(2))of approximately 0.014 and 0.998,respectively,for the RB5 removal efficiency,outperforming CCD-NPRSM with MSE and R^(2) of 0.518 and 0.998,respectively.Overall,the hybrid ANN-XGBoost approach is the most feasible technique for assessing the electrochemical treatment efficiency in RB5 dye wastewater decolourisation.展开更多
Psoriasis is a hereditary,autoimmune,chronic illness that influences the immune system and can have both cutaneous and systemic symptoms.It can seriously impair a patient’s quality of life.Psoriasis affects 2.3 perce...Psoriasis is a hereditary,autoimmune,chronic illness that influences the immune system and can have both cutaneous and systemic symptoms.It can seriously impair a patient’s quality of life.Psoriasis affects 2.3 percent of people globally and has a significant financial cost for those who suffer from it.Genes and environmental factors are the primary etiological factors.Dendritic cells,T cells,human neutrophilic peptides,lipoprotein-2,galactosin-3,fractalkine,vaspin,and familial predispositions,among other factors,are characteristics of the pathophysiology of psoriasis.Conventional psoriasis treatments for patients include corticosteroids,biological agents,vitamin D3 analogs,acitretin,calcineurin inhibitors,cyclosporine,methotrexate,and phototherapy.Growing in popularity as a multidisciplinary field of study,nano dermatology is being used to treat psoriasis.Over the years,major advancements have been made in understanding its complex pathogenesis and developing more effective,targeted treatments.Medication delivery methods utilizing nanocarriers demonstrate promise in treating psoriasis because they improve medication penetration,reduce side effects,and provide targeted action at the afflicted areas.Because of their biological compatibility,adaptability,and capacity for carrying a variety of therapeutic substances,lipid-based and polymer-based nanocarriers have demonstrated exceptional promise among them.This article summarizes the pathogenesis,epidemiology,clinical diagnosis,and conventional psoriasis treatments.Furthermore,the review includes an overview of various nanotechnology-based psoriasis treatments.展开更多
Electric desalting wastewater(EDW)is one of the petrochemical wastewater generated in the production process of petrochemical industry,due to the instability of its water quality,the traditional wastewater treatment t...Electric desalting wastewater(EDW)is one of the petrochemical wastewater generated in the production process of petrochemical industry,due to the instability of its water quality,the traditional wastewater treatment technology is complex,high energy consumption,and will produce waste causing secondary pollution,posing challenges in terms of environmental protection,technology,and economy.This study utilized an on-site test to investigate the possibility of a new short-process physical method to replace traditional electro-chemical,oil-separation,and two-stage air floating physical chemistry processes,in response to optimizing the treatment effect,thus reducing the cost of treatment and carbon emissions.Following this test,this new short-flow physical method process could improve the efficiency of oil and suspend solid(SS)removal by 15.48%and 58.72%,and providing 78.37%and 75.55%the operating costs and carbon emissions savings,respectively.This system also reduced the production of waste solids,volatile organic compounds,and other three-waste compared with the traditional process.These benefits offer environmental and economic advantages,and this process serves as an efficient strategy to treat wastewater for electric desalination,and can be served as a completely new technological and process option for the treatment of EDW.展开更多
This study systematically conducted preparation optimization and performance investigations on Co-modified Ce/TiO_(2) catalysts,with a focus on examining how preparation methods and Co loading regulate the catalyst’s...This study systematically conducted preparation optimization and performance investigations on Co-modified Ce/TiO_(2) catalysts,with a focus on examining how preparation methods and Co loading regulate the catalyst’s low-temperature denitrification activity.After identifying optimal preparation parameters via condition screening,multiple characterization techniques-including BET,XRD,XPS,H_(2)-TPR and in situ DRIFTS-were employed to deeply analyze the catalyst’s physicochemical properties and reaction mechanism.Results demonstrated that compared to the impregnation and co-precipitation methods,the Ce-Co_(0.025)/TiO_(2)-SG catalyst(prepared by the sol-gel method with a Co/Ti mass ratio of 0.025)exhibited significantly superior denitrification activity:NO conversion remained stably above 95%in the 225−350℃ temperature range,and it displayed high N_(2) selectivity.Characterization analysis revealed that abundant surface oxygen vacancies,a high proportion of Ce^(3+) species,and prominent acidic sites collectively contributed to enhancing its low-temperature denitrification performance.This work provides reference value for the development of highly efficient low-temperature denitrification catalysts.展开更多
In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to ...In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to obtain the maximal positive definite solution of nonlinear matrix equation X+A^(*)X|^(-α)A=Q with the case 0<α≤1.Based on this method,a new iterative algorithm is developed,and its convergence proof is given.Finally,two numerical examples are provided to show the effectiveness of the proposed method.展开更多
This study presents an effective hybrid simulation approach for simulating broadband ground motion in complex near-fault locations.The approach utilizes a deterministic approach based on the spectral element method(SE...This study presents an effective hybrid simulation approach for simulating broadband ground motion in complex near-fault locations.The approach utilizes a deterministic approach based on the spectral element method(SEM),which is used to simulate low-frequency ground motion(f<1 Hz)by incorporating an innovative efficient discontinuous Galerkin(DG)method for grid division to accurately model basin sedimentary layers at reduced costs.It also introduces a comprehensive hybrid source model for high-frequency random scattering and a nonlinear analysis module for basin sedimentary layers.Deterministic outcomes are combined with modified three-dimensional stochastic finite fault method(3D-EXSIM)simulations of high-frequency ground motion(f>1 Hz).A fourth-order Butterworth filter with zero phase shift is employed for time-domain filtering of low-and high-frequency time series at a crossover frequency of 1 Hz,merging the low and high-frequency ground motions into a broadband time series.Taking an Ms 6.8 Luding earthquake,as an example,this hybrid method was used for a rapid and efficient simulation analysis of broadband ground motion in the region.The accuracy and efficiency of this hybrid method were verified through comparisons with actually observed station data and empirical attenuation curves.Deterministic method simulation results revealed the effects of mountainous topography,basin effects,nonlinear effects within the basin’s sedimentary layers,and a coupling interaction between the basin and the mountains.The findings are consistent with similar studies,showing that near-fault sedimentary basins significantly focus and amplify strong ground motion,and the soil’s nonlinear behavior in the basin influences ground motion to varying extents at different distances from the fault.The mountainous topography impacts the basin’s response to ground motion,leading to barrier effects.This research provides a scientific foundation for seismic zoning,urban planning,and seismic design in nearfault mountain basin regions.展开更多
The TiB+TiC dual-reinforced B_(4)C/TC4 composite was in-situ fabricated via incorporating 0.5wt%B_(4)C reinforcement during the laser melting deposition process.Different heat treatments of annealing and solid solutio...The TiB+TiC dual-reinforced B_(4)C/TC4 composite was in-situ fabricated via incorporating 0.5wt%B_(4)C reinforcement during the laser melting deposition process.Different heat treatments of annealing and solid solution were used to regulate the microstructure,mechanical properties,and corrosion properties of B_(4)C/TC4 composite.Results show that with the increase in temperature from 500℃to 800°C,partial lamellarα-Ti in the as-deposited sample is gradually transformed into equiaxedα-Ti,accompanied by the disappearance of basketweave microstructure.At 1100°C,a small portion of TiC phase suffers fusion.This composite exhibits the optimal combination of strength and plasticity after annealing at 500℃for 4 h followed by furnace cooling,which is attributed to the stress release effect and the refined basketweave microstructure.However,this composite shows a decline in corrosion resistance after various heat treatments due to grain coarsening and micro-galvanic corrosion.展开更多
Heat treatment is applied towood to improve various properties of thematerial.Thepresent study focuses on the colour changes of wood veneer samples due to heat treatment.Native wood species fromJapan and Europe,such a...Heat treatment is applied towood to improve various properties of thematerial.Thepresent study focuses on the colour changes of wood veneer samples due to heat treatment.Native wood species fromJapan and Europe,such as Japanese oak(Quercus mongolica var.crispula),field maple(Acer campestre)and Scots pine(Pinus sylvestris)were used in the experiments.A laboratory-type oven was used to apply the heat at a temperature of 190○C,in the presence of oxygen,for different periods,gradually increasing from 5 to 40 min.The CIELab system(a colour space defined by the International Commission on Illumination)and Near Infrared Spectroscopy(NIR)were employed to evaluate the colour modifications on the samples.As expected,the heat treatment affected the colour of the samples.The lightness index decreased across the three wood species during the treatment.The chroma coordinates changed for pine and maple,while little change occurred in Japanese oak.The overall total colour differences reached their maximum at the final 40-min interval for all wood types.Based on the NIR evaluation,it was found that drastic thermal denaturation of cellulose was unlikely to occur,and the changes in the intermolecular interaction of water affected the colour of the specimens.The data and information of this study could be useful for industrial applications where the veneer of such species is desired.Such heat-treated veneers can be considered as value-added products in furniture manufacturing as well as restoration of furniture units where such veneer is used as an overlay.展开更多
The global prevalence of metabolic-associated fatty liver disease(MAFLD)is on the rise,seriously threatening human health.Currently,no specific approved drugs are available for its treatment.This paper reviews the pat...The global prevalence of metabolic-associated fatty liver disease(MAFLD)is on the rise,seriously threatening human health.Currently,no specific approved drugs are available for its treatment.This paper reviews the pathogenesis of MAFLD,covering aspects like lipid accumulation and insulin resistance,oxidative stress,endoplasmic reticulum stress(ERS),lipotoxicity-induced hepatocyte damage,and fibrosis.It also elaborates on multiple treatment approaches for MAFLD,including metabolic regulation,improvement of the gut-liver axis interaction,modulation of immune and inflammatory pathways,enhancement of the adipose tissue-liver interaction,alleviation of fibrosis,prevention of hepatocyte injury,and traditional Chinese medicine(TCM)external therapies.Additionally,natural product research advancements,individual Chinese medicine components,and mixed herbal formulas for MAFLD treatment is provided.Many natural products and traditional Chinese medicines exhibit favorable effects in regulating lipid metabolism,anti-inflammation,and anti-oxidation,offering new directions and potential drug options for MAFLD treatment.This is expected to provide a reference for future clinical treatment and drug development.展开更多
Colorectal cancer(CRC)is the third most common malignancy worldwide and the second leading cause of cancer-related deaths,accounting for approximately 10%of all cancer cases.By 2050,CRC incidence is expected to rise s...Colorectal cancer(CRC)is the third most common malignancy worldwide and the second leading cause of cancer-related deaths,accounting for approximately 10%of all cancer cases.By 2050,CRC incidence is expected to rise substantially,driven by population aging and greater exposure to risk factors in developing countries.Despite advances in medicine and pharmacy,the effectiveness of available treatments remains limited,underscoring the urgent need for innovative therapeutic strategies.This review summarizes and critically evaluates currently available CRC therapies and explores new emerging directions.Particular attention is given to the role of immunotherapy,targeted therapies,nanotechnology-based approaches,metal-based compounds,PROTAC technology,and personalized medicine,with emphasis on their efficacy,safety,accessibility,and mechanisms of drug resistance.In conclusion,surgery and chemotherapy remain the backbone of CRC treatment,but novel therapeutic approaches are reshaping the treatment landscape.Emerging strategies may offer improved patient tolerability and survival outcomes by reducing the occurrence of burdensome adverse effects.Persistent challenges such as drug toxicity,the emergence of resistance mechanisms,and inequalities in access to innovative therapies underscore the need for further translational research.Integrating personalized therapeutic approaches will also be crucial to achieving more effective,safer,and accessible treatment strategies for CRC.展开更多
The concept of Damage Control Surgery(DCS)emphasizes prioritizing hemorrhage control,preventing hypothermia,correcting coagulopathy,and acidosis in trauma treatment.The application of the DCS concept in trauma treatme...The concept of Damage Control Surgery(DCS)emphasizes prioritizing hemorrhage control,preventing hypothermia,correcting coagulopathy,and acidosis in trauma treatment.The application of the DCS concept in trauma treatment at grassroots hospitals faces numerous challenges such as limited resources,high technical difficulty,and insufficient multidisciplinary collaboration.Therefore,DCS strategies need to be adapted to simplified processes to create conditions for subsequent treatment.This paper retrieves relevant literature to discuss the proposal,promotion,and application of the DCS concept,aiming to provide evidence-based basis for optimizing trauma treatment outcomes at grassroots hospitals.展开更多
Vibrio harveyi,a Gram-negative bacterium ubiquitous in marine environments,is recognized as an opportunistic pathogen affecting various aquatic organisms such as fish,shrimp,and shellfish.To enhance its environmental ...Vibrio harveyi,a Gram-negative bacterium ubiquitous in marine environments,is recognized as an opportunistic pathogen affecting various aquatic organisms such as fish,shrimp,and shellfish.To enhance its environmental resilience and adaptive capacity,V.harveyi employs a complex quorum sensing mechanism to modulate its virulence factors,such as bioluminescence,biofilm formation,and motility.Therefore,targeting the quorum sensing of V.harveyi could be a promising strategy to develop novel approaches to ensure the microbial safety of seafood products.This study aims to evaluate the impact of curcumin-mediated photo/sonodynamic treatment on quorum sensing in V.harveyi and its regulated functions.The results indicate a significant decrease of luminescence in V.harveyi following curcumin-mediated photo/sonodynamic treatment.Correspondingly,the biofilm formation ability and bacterial motility of V.harveyi were also greatly impaired by the treatment.Notably,the production of reactive oxygen species in bacteria induced by the photo/sonodynamic treatment could be the underlying mechanism involved in the observed disruption of quorum sensing.These findings underscore the great potential of photo/sonodynamic treatment as a promising strategy to disrupt quorum sensing and mitigate the virulence of V.harveyi,thereby contributing to the development of effective control strategies against this pervasive pathogen.展开更多
With the growth of global protein demand and the development of plant-based foods,pea protein,as a low-allergenic,nutritionally balanced and environmentally friendly plant protein,has shown great potential in replacin...With the growth of global protein demand and the development of plant-based foods,pea protein,as a low-allergenic,nutritionally balanced and environmentally friendly plant protein,has shown great potential in replacing animal protein.Pea protein is mainly composed of globulin and albumin,with a protein content of 20%to 30%,and has a balanced amino acid composition,as well as being rich in minerals and dietary fiber.It also possesses good foaming,gelling,emulsifying and antioxidant functional properties.However,pea protein also has inherent defects that limit its application in the food industry.This article systematically reviews the extraction techniques,functional properties,modification methods and application fields of pea protein,and focuses on evaluating the effects of different extraction and modification strategies on protein yield and functional properties.Research shows that ultrasonic-assisted alkaline extraction can reduce solvent usage by 55%,shorten extraction time by 50%,and increase extraction rate by 12.51%;under optimized conditions,ultrafiltration membrane technology can achieve a protein purity of 91%.In terms of modification,ultrasonic treatment increases foaming capacity by 37.4%,and phenolic cross-linking increases gel strength from 3.0 kPa to 48 kPa.This article provides data support and theoretical reference for the efficient extraction and functional optimization of pea protein,and has promoting significance for its wide application in plant-based foods.展开更多
AIM:To present an overview of the research on global glaucoma treatment in the last decade in terms of publication year,journals,countries/regions,organizations,references,and keywords,to investigate the current resea...AIM:To present an overview of the research on global glaucoma treatment in the last decade in terms of publication year,journals,countries/regions,organizations,references,and keywords,to investigate the current research international trends and hot topics in this area.METHODS:Bibliometric analysis was conducted on 9128 articles in the Web of Science Core Collection(WoSCC;Clarivate)database.Quantitative and qualitative analysis was employed using VOSviewer(v1.6.18),Pajek(v1.0.0.0),and CiteSpace(v6.1.R2)software.RESULTS:The 9128 papers relating to glaucoma treatment were published from April 2013 to April 2023,of which 7482 articles(82%)were original research articles and 1464(18%)were review articles.The United States(2867)and Johns Hopkins University(166)were the most productive country and institution,respectively,but the University College London had the highest h-index(54).The Journal of Glaucoma was the most productive and Ophthalmology had the highest h-index compared with other journals.The Keywords of interest included treatment surgery,cyclophotocoagulation,minimally invasive glaucoma surgery(MIGS),trabeculectomy,baerveldt,epidemiology,medication adherence,nanoparticle,optical coherence tomography(OCT),gene therapy,and artificial intelligence(AI).Glaucoma surgery appeared as a current research hotspot through the analysis of keywords.CONCLUSION:This study provides insights into the research trends and potential research hotspots in the treatment of glaucoma.This will help researchers to evaluate research policies and to promote international cooperation.展开更多
[Objectives]This study was conducted to establish a quantitative assessment method for the textural quality of chieh-qua fruit.[Methods]Using two modes of a texture analyzer,namely TPA(texture profile analysis)and pun...[Objectives]This study was conducted to establish a quantitative assessment method for the textural quality of chieh-qua fruit.[Methods]Using two modes of a texture analyzer,namely TPA(texture profile analysis)and puncture,the index data of the fruit were obtained by setting different trigger forces,deformation levels,test speeds,as well as puncture speeds and puncture depths.The data included TPA hardness,adhesiveness,springiness,cohesiveness,gumminess,chewiness,resilience,as well as skin hardness,skin toughness,flesh hardness,fracturability,and compactness.[Results]Different deformation levels had a significant impact on all parameters.Hardness,adhesiveness,gumminess and chewiness showed a trend of first increasing and then decreasing with the deformation level increasing.When the deformation level was 30%,the adhesiveness,gumminess and chewiness reached their maximum values.When the deformation level was 50%,TPA hardness reached its maximum.When the compression speed was 3 mm/s,the measured values of TPA hardness,adhesiveness,chewiness,and resilience were at their maximums.The skin hardness varied significantly under different trigger forces.When the trigger force was 15 g,the skin hardness reached a maximum value of 944.63 g,and the skin toughness,flesh hardness,fracturability,and compactness also reach their maximum values respectively.When the puncture depth was 12 mm,the flesh hardness and skin toughness reached their maximums of 682.51 g and 1.82 mm,respectively.In the TPA mode,the flesh hardness of chieh-qua showed an extremely significant negative correlation with springiness,cohesiveness,and resilience(P<0.01).The fruit fracturability detected by puncture had an extremely significant positive correlation with compactness(P<0.01).[Conclusions]The evaluation method for measuring chieh-qua texture by combining TPA and the puncture mode could accurately and quantitatively reflect the differences in the flesh texture quality of chieh-qua.The optimal parameters for texture measurement of chieh-qua fruit were determined as a 15 g trigger force with 50%deformation and a 3 mm/s compression speed in TPA mode,and a 15 g trigger force with a 12 mm puncture depth in puncture mode.Puncture speed was found to have no significant effect on the texture indices of chieh-qua.展开更多
文摘Dairy wastewater,a kind of high concentration organic wastewater,is produced in large quantities and difficult to treat,and has a negative impact on the ecological environment.In this study,the source,composition,water quality characteristics of dairy wastewater and its impact on the ecological environment were analyzed,and the treatment methods of dairy wastewater at home and abroad in recent years were summarized,in order to provide a reference for the treatment of dairy wastewater.
文摘Diabetic foot(DF)has emerged as one of the most common chronic consequences of diabetes mellitus,characterized by prolonged disease duration,high treatment costs,a poor prognosis,and a high disability rate.Diabetic high-risk foot is the early stage of diabetic foot,the“disease prevention”of“treating no disease”,which provides a critical window for clinical prevention and treatment.Traditional Chinese medicine(TCM)has emphasized the importance of preventive health care since ancient times.External therapies such as acupuncture,massage,acupoint injection,foot bath fumigation,and moxibustion have the advantages of simplicity,low cost,precise efficacy,and fewer side effects in preventing and treating diabetic high-risk foot.The multidisciplinary synergistic model formed by TCM complementary therapies and modern medical treatments,such as nutritional,peripheral nerve,and blood glucose regulation,provides new ideas for establishing standardized prevention and treatment protocols.In this paper,studies related to TCM-related complementary therapies for diabetic high-risk feet are systematically reviewed.Current advances in external application in TCM were described to better understand its effectiveness and safety in elderly patients.
基金supporting the research project under the USK Leading Research Program-Doctoral Acceleration Scheme(PRRU-PD,Grant Number:444/UN11.2.1/PG.01.03/SPK/PTNBH/2024)coordinated by the Institute for Research and Community Services(LPPM-USK).
文摘As the world’s largest palm oil producer,Indonesia significantly benefits from its palm oil industry but also faces serious environmental challenges from palm oil mill effluent(POME)-a high-strength wastewater containing substantial organic matter,nutrients,suspended solids,and various chemical compounds.Sustainable and effective wastewater treatment strategies are urgently needed to address this issue.This review presents a comprehensive analysis of existing POME treatment technologies,including anaerobic digestion(AD),advanced oxidation processes(AOPs),membrane filtration,adsorption,phytoremediation,and microalgae-based systems.Each method is examined in terms of treatment efficiency,operational feasibility,and potential for imple-mentation under Indonesian conditions.While advanced processes,such as AOPs and membrane filtration,achieve high pollutant removal,they are often limited by operational costs.In contrast,biological approaches,such as AD and phytoremediation,offer both environmental benefits and economic value through the recovery of biogas,biofertilizers,and biomass.This review highlights the potential for integrating wastewater purification with resource recovery and valorization,supporting a shift toward more circular and sustainable management of POME.The insights provided are intended to guide future research,inform policy decisions,and facilitate the industrial adoption of optimized treatment systems.
文摘In their study,Han et al compared the efficacy of bevacizumab plus sindilizumab plus interventional therapy with that of lenvatinib plus sindilizumab plus interventional therapy for patients with intermediate and advanced hepatocellular carcinoma.The triple therapy,which integrates interventional therapy,targeted therapy,and immunotherapy,has emerged as a promising research focus in the treatment of liver cancer.Consequently,it is of utmost significance to select an appropriate combination of interventional therapy,targeted therapy,and immunotherapy for patients suffering from intermediate and advanced liver cancer.
基金National Natural Science Foundation of China(52172108)National Key R&D Program of China(2022YFB3707700)Strategic Priority Research Program of the Chinese Academy of Sciences(XDC0144005)。
文摘Silicon carbide fibers are considered ideal reinforcing materials for ceramic matrix composites due to their excellent mechanical properties and high-temperature performance.Different types of fibers necessitate individual investigation due to variations in their composition and fabrication processes.This study presents a comprehensive investigation into evolution of the mechanical properties,surface microstructure,and composition of Shicolon-Ⅱ fibers subjected to argon heat treatment at temperatures ranging from 1300℃to 1700℃.The Shicolon-Ⅱ fibers are composed of small-sized β-SiC grains,SiC_(x)O_(y) amorphous phase,and a minor amount of graphite microcrystals.Following treatment in an argon atmosphere at 1300℃,the fibers maintain a monofilament tensile strength of 3.620 GPa,corresponding to a retention of 98.32%.This strength diminishes to 2.875 GPa,equating to a retention of 78.08%,after treatment at 1500℃.The reduction in mechanical properties of the fibers can be ascribed to the decomposition of the amorphous phase and the growth of β-SiC grains.Furthermore,creep resistance is an essential factor influencing the long-term performance of composite materials.After treatment at temperatures above 1400℃,the high-temperature creep resistance of the fibers is significantly enhanced due to growth of β-SiC grains.This study offers valuable theoretical insights into high-temperature applications of second-generation fibers,contributing to an enhanced understanding of their performance under extreme conditions.
文摘The highly efficient electrochemical treatment technology for dye-polluted wastewater is one of hot research topics in industrial wastewater treatment.This study reported a three-dimensional electrochemical treatment process integrating graphite intercalation compound(GIC)adsorption,direct anodic oxidation,and·OH oxidation for decolourising Reactive Black 5(RB5)from aqueous solutions.The electrochemical process was optimised using the novel progressive central composite design-response surface methodology(CCD-NPRSM),hybrid artificial neural network-extreme gradient boosting(hybrid ANN-XGBoost),and classification and regression trees(CART).CCD-NPRSM and hybrid ANN-XGBoost were employed to minimise errors in evaluating the electrochemical process involving three manipulated operational parameters:current density,electrolysis(treatment)time,and initial dye concentration.The optimised decolourisation efficiencies were 99.30%,96.63%,and 99.14%for CCD-NPRSM,hybrid ANN-XGBoost,and CART,respectively,compared to the 98.46%RB5 removal rate observed experimentally under optimum conditions:approximately 20 mA/cm^(2) of current density,20 min of electrolysis time,and 65 mg/L of RB5.The optimised mineralisation efficiencies ranged between 89%and 92%for different models based on total organic carbon(TOC).Experimental studies confirmed that the predictive efficiency of optimised models ranked in the descending order of hybrid ANN-XGBoost,CCD-NPRSM,and CART.Model validation using analysis of variance(ANOVA)revealed that hybrid ANN-XGBoost had a mean squared error(MSE)and a coefficient of determination(R^(2))of approximately 0.014 and 0.998,respectively,for the RB5 removal efficiency,outperforming CCD-NPRSM with MSE and R^(2) of 0.518 and 0.998,respectively.Overall,the hybrid ANN-XGBoost approach is the most feasible technique for assessing the electrochemical treatment efficiency in RB5 dye wastewater decolourisation.
文摘Psoriasis is a hereditary,autoimmune,chronic illness that influences the immune system and can have both cutaneous and systemic symptoms.It can seriously impair a patient’s quality of life.Psoriasis affects 2.3 percent of people globally and has a significant financial cost for those who suffer from it.Genes and environmental factors are the primary etiological factors.Dendritic cells,T cells,human neutrophilic peptides,lipoprotein-2,galactosin-3,fractalkine,vaspin,and familial predispositions,among other factors,are characteristics of the pathophysiology of psoriasis.Conventional psoriasis treatments for patients include corticosteroids,biological agents,vitamin D3 analogs,acitretin,calcineurin inhibitors,cyclosporine,methotrexate,and phototherapy.Growing in popularity as a multidisciplinary field of study,nano dermatology is being used to treat psoriasis.Over the years,major advancements have been made in understanding its complex pathogenesis and developing more effective,targeted treatments.Medication delivery methods utilizing nanocarriers demonstrate promise in treating psoriasis because they improve medication penetration,reduce side effects,and provide targeted action at the afflicted areas.Because of their biological compatibility,adaptability,and capacity for carrying a variety of therapeutic substances,lipid-based and polymer-based nanocarriers have demonstrated exceptional promise among them.This article summarizes the pathogenesis,epidemiology,clinical diagnosis,and conventional psoriasis treatments.Furthermore,the review includes an overview of various nanotechnology-based psoriasis treatments.
基金supported by the National Natural Science Foundation of China(Nos.52300086 and 52025103)the Postdoctoral Fellowship Program of CPSF(No.GZB20230215).
文摘Electric desalting wastewater(EDW)is one of the petrochemical wastewater generated in the production process of petrochemical industry,due to the instability of its water quality,the traditional wastewater treatment technology is complex,high energy consumption,and will produce waste causing secondary pollution,posing challenges in terms of environmental protection,technology,and economy.This study utilized an on-site test to investigate the possibility of a new short-process physical method to replace traditional electro-chemical,oil-separation,and two-stage air floating physical chemistry processes,in response to optimizing the treatment effect,thus reducing the cost of treatment and carbon emissions.Following this test,this new short-flow physical method process could improve the efficiency of oil and suspend solid(SS)removal by 15.48%and 58.72%,and providing 78.37%and 75.55%the operating costs and carbon emissions savings,respectively.This system also reduced the production of waste solids,volatile organic compounds,and other three-waste compared with the traditional process.These benefits offer environmental and economic advantages,and this process serves as an efficient strategy to treat wastewater for electric desalination,and can be served as a completely new technological and process option for the treatment of EDW.
基金Supported by the National Key Research and Development Program of China (2023YFB4102903)。
文摘This study systematically conducted preparation optimization and performance investigations on Co-modified Ce/TiO_(2) catalysts,with a focus on examining how preparation methods and Co loading regulate the catalyst’s low-temperature denitrification activity.After identifying optimal preparation parameters via condition screening,multiple characterization techniques-including BET,XRD,XPS,H_(2)-TPR and in situ DRIFTS-were employed to deeply analyze the catalyst’s physicochemical properties and reaction mechanism.Results demonstrated that compared to the impregnation and co-precipitation methods,the Ce-Co_(0.025)/TiO_(2)-SG catalyst(prepared by the sol-gel method with a Co/Ti mass ratio of 0.025)exhibited significantly superior denitrification activity:NO conversion remained stably above 95%in the 225−350℃ temperature range,and it displayed high N_(2) selectivity.Characterization analysis revealed that abundant surface oxygen vacancies,a high proportion of Ce^(3+) species,and prominent acidic sites collectively contributed to enhancing its low-temperature denitrification performance.This work provides reference value for the development of highly efficient low-temperature denitrification catalysts.
基金Supported in part by Natural Science Foundation of Guangxi(2023GXNSFAA026246)in part by the Central Government's Guide to Local Science and Technology Development Fund(GuikeZY23055044)in part by the National Natural Science Foundation of China(62363003)。
文摘In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to obtain the maximal positive definite solution of nonlinear matrix equation X+A^(*)X|^(-α)A=Q with the case 0<α≤1.Based on this method,a new iterative algorithm is developed,and its convergence proof is given.Finally,two numerical examples are provided to show the effectiveness of the proposed method.
基金National Natural Science Foundation of China under Grant Nos.U2139208 and 52278516Key Laboratory of Earthquake Engineering and Engineering Vibration,China Earthquake Administration under Grant No.2024D15Key Laboratory of Soft Soil Characteristic and Engineering Environment,Tianjin Chengjian University under Grant No.2022SCEEKL003。
文摘This study presents an effective hybrid simulation approach for simulating broadband ground motion in complex near-fault locations.The approach utilizes a deterministic approach based on the spectral element method(SEM),which is used to simulate low-frequency ground motion(f<1 Hz)by incorporating an innovative efficient discontinuous Galerkin(DG)method for grid division to accurately model basin sedimentary layers at reduced costs.It also introduces a comprehensive hybrid source model for high-frequency random scattering and a nonlinear analysis module for basin sedimentary layers.Deterministic outcomes are combined with modified three-dimensional stochastic finite fault method(3D-EXSIM)simulations of high-frequency ground motion(f>1 Hz).A fourth-order Butterworth filter with zero phase shift is employed for time-domain filtering of low-and high-frequency time series at a crossover frequency of 1 Hz,merging the low and high-frequency ground motions into a broadband time series.Taking an Ms 6.8 Luding earthquake,as an example,this hybrid method was used for a rapid and efficient simulation analysis of broadband ground motion in the region.The accuracy and efficiency of this hybrid method were verified through comparisons with actually observed station data and empirical attenuation curves.Deterministic method simulation results revealed the effects of mountainous topography,basin effects,nonlinear effects within the basin’s sedimentary layers,and a coupling interaction between the basin and the mountains.The findings are consistent with similar studies,showing that near-fault sedimentary basins significantly focus and amplify strong ground motion,and the soil’s nonlinear behavior in the basin influences ground motion to varying extents at different distances from the fault.The mountainous topography impacts the basin’s response to ground motion,leading to barrier effects.This research provides a scientific foundation for seismic zoning,urban planning,and seismic design in nearfault mountain basin regions.
基金Tianjin Municipal Natural Science Foundation(23JCYBJC00040)National Natural Science Foundation of China(52175369)。
文摘The TiB+TiC dual-reinforced B_(4)C/TC4 composite was in-situ fabricated via incorporating 0.5wt%B_(4)C reinforcement during the laser melting deposition process.Different heat treatments of annealing and solid solution were used to regulate the microstructure,mechanical properties,and corrosion properties of B_(4)C/TC4 composite.Results show that with the increase in temperature from 500℃to 800°C,partial lamellarα-Ti in the as-deposited sample is gradually transformed into equiaxedα-Ti,accompanied by the disappearance of basketweave microstructure.At 1100°C,a small portion of TiC phase suffers fusion.This composite exhibits the optimal combination of strength and plasticity after annealing at 500℃for 4 h followed by furnace cooling,which is attributed to the stress release effect and the refined basketweave microstructure.However,this composite shows a decline in corrosion resistance after various heat treatments due to grain coarsening and micro-galvanic corrosion.
文摘Heat treatment is applied towood to improve various properties of thematerial.Thepresent study focuses on the colour changes of wood veneer samples due to heat treatment.Native wood species fromJapan and Europe,such as Japanese oak(Quercus mongolica var.crispula),field maple(Acer campestre)and Scots pine(Pinus sylvestris)were used in the experiments.A laboratory-type oven was used to apply the heat at a temperature of 190○C,in the presence of oxygen,for different periods,gradually increasing from 5 to 40 min.The CIELab system(a colour space defined by the International Commission on Illumination)and Near Infrared Spectroscopy(NIR)were employed to evaluate the colour modifications on the samples.As expected,the heat treatment affected the colour of the samples.The lightness index decreased across the three wood species during the treatment.The chroma coordinates changed for pine and maple,while little change occurred in Japanese oak.The overall total colour differences reached their maximum at the final 40-min interval for all wood types.Based on the NIR evaluation,it was found that drastic thermal denaturation of cellulose was unlikely to occur,and the changes in the intermolecular interaction of water affected the colour of the specimens.The data and information of this study could be useful for industrial applications where the veneer of such species is desired.Such heat-treated veneers can be considered as value-added products in furniture manufacturing as well as restoration of furniture units where such veneer is used as an overlay.
基金supported by the National Natural Science Foundation of China(82574477)the Jiangsu Provincial Traditional Chinese Medicine Science and Technology Development Plan(QN202426)+5 种基金Jiangsu Province“333 High-level Talents Training Project”((2024)3-0189)Youth Talent Support Project of the Jiangsu Association for Science and Technology(TJ-2023-053)Shanxi Provincial Department-Municipal Key Laboratory Cultivation Base for Quality Enhancement and Utilization of Shangdang Chinese Medicinal Materials(KF202401)Fundamental Research Program of Shanxi Province(202403021221211)the research project supported by the Shanxi Scholarship Council of China(No.2023-158)Open Project of Key Laboratory of Tibetan Medicine Basic Research,Ministry of Education.
文摘The global prevalence of metabolic-associated fatty liver disease(MAFLD)is on the rise,seriously threatening human health.Currently,no specific approved drugs are available for its treatment.This paper reviews the pathogenesis of MAFLD,covering aspects like lipid accumulation and insulin resistance,oxidative stress,endoplasmic reticulum stress(ERS),lipotoxicity-induced hepatocyte damage,and fibrosis.It also elaborates on multiple treatment approaches for MAFLD,including metabolic regulation,improvement of the gut-liver axis interaction,modulation of immune and inflammatory pathways,enhancement of the adipose tissue-liver interaction,alleviation of fibrosis,prevention of hepatocyte injury,and traditional Chinese medicine(TCM)external therapies.Additionally,natural product research advancements,individual Chinese medicine components,and mixed herbal formulas for MAFLD treatment is provided.Many natural products and traditional Chinese medicines exhibit favorable effects in regulating lipid metabolism,anti-inflammation,and anti-oxidation,offering new directions and potential drug options for MAFLD treatment.This is expected to provide a reference for future clinical treatment and drug development.
文摘Colorectal cancer(CRC)is the third most common malignancy worldwide and the second leading cause of cancer-related deaths,accounting for approximately 10%of all cancer cases.By 2050,CRC incidence is expected to rise substantially,driven by population aging and greater exposure to risk factors in developing countries.Despite advances in medicine and pharmacy,the effectiveness of available treatments remains limited,underscoring the urgent need for innovative therapeutic strategies.This review summarizes and critically evaluates currently available CRC therapies and explores new emerging directions.Particular attention is given to the role of immunotherapy,targeted therapies,nanotechnology-based approaches,metal-based compounds,PROTAC technology,and personalized medicine,with emphasis on their efficacy,safety,accessibility,and mechanisms of drug resistance.In conclusion,surgery and chemotherapy remain the backbone of CRC treatment,but novel therapeutic approaches are reshaping the treatment landscape.Emerging strategies may offer improved patient tolerability and survival outcomes by reducing the occurrence of burdensome adverse effects.Persistent challenges such as drug toxicity,the emergence of resistance mechanisms,and inequalities in access to innovative therapies underscore the need for further translational research.Integrating personalized therapeutic approaches will also be crucial to achieving more effective,safer,and accessible treatment strategies for CRC.
文摘The concept of Damage Control Surgery(DCS)emphasizes prioritizing hemorrhage control,preventing hypothermia,correcting coagulopathy,and acidosis in trauma treatment.The application of the DCS concept in trauma treatment at grassroots hospitals faces numerous challenges such as limited resources,high technical difficulty,and insufficient multidisciplinary collaboration.Therefore,DCS strategies need to be adapted to simplified processes to create conditions for subsequent treatment.This paper retrieves relevant literature to discuss the proposal,promotion,and application of the DCS concept,aiming to provide evidence-based basis for optimizing trauma treatment outcomes at grassroots hospitals.
基金financially supported by National Natural Science Foundation of China(32272450)Science Fund for Distinguished Young Scholars of Fujian Province(2023J06020)Special Funds for Science and Technology Innovation of Fujian Agriculture and Forestry University(KFB23132A)。
文摘Vibrio harveyi,a Gram-negative bacterium ubiquitous in marine environments,is recognized as an opportunistic pathogen affecting various aquatic organisms such as fish,shrimp,and shellfish.To enhance its environmental resilience and adaptive capacity,V.harveyi employs a complex quorum sensing mechanism to modulate its virulence factors,such as bioluminescence,biofilm formation,and motility.Therefore,targeting the quorum sensing of V.harveyi could be a promising strategy to develop novel approaches to ensure the microbial safety of seafood products.This study aims to evaluate the impact of curcumin-mediated photo/sonodynamic treatment on quorum sensing in V.harveyi and its regulated functions.The results indicate a significant decrease of luminescence in V.harveyi following curcumin-mediated photo/sonodynamic treatment.Correspondingly,the biofilm formation ability and bacterial motility of V.harveyi were also greatly impaired by the treatment.Notably,the production of reactive oxygen species in bacteria induced by the photo/sonodynamic treatment could be the underlying mechanism involved in the observed disruption of quorum sensing.These findings underscore the great potential of photo/sonodynamic treatment as a promising strategy to disrupt quorum sensing and mitigate the virulence of V.harveyi,thereby contributing to the development of effective control strategies against this pervasive pathogen.
文摘With the growth of global protein demand and the development of plant-based foods,pea protein,as a low-allergenic,nutritionally balanced and environmentally friendly plant protein,has shown great potential in replacing animal protein.Pea protein is mainly composed of globulin and albumin,with a protein content of 20%to 30%,and has a balanced amino acid composition,as well as being rich in minerals and dietary fiber.It also possesses good foaming,gelling,emulsifying and antioxidant functional properties.However,pea protein also has inherent defects that limit its application in the food industry.This article systematically reviews the extraction techniques,functional properties,modification methods and application fields of pea protein,and focuses on evaluating the effects of different extraction and modification strategies on protein yield and functional properties.Research shows that ultrasonic-assisted alkaline extraction can reduce solvent usage by 55%,shorten extraction time by 50%,and increase extraction rate by 12.51%;under optimized conditions,ultrafiltration membrane technology can achieve a protein purity of 91%.In terms of modification,ultrasonic treatment increases foaming capacity by 37.4%,and phenolic cross-linking increases gel strength from 3.0 kPa to 48 kPa.This article provides data support and theoretical reference for the efficient extraction and functional optimization of pea protein,and has promoting significance for its wide application in plant-based foods.
基金Suppotred by Tianjin Key Medical Discipline Construction Project(No.TJYXZDXK-3-004A-2).
文摘AIM:To present an overview of the research on global glaucoma treatment in the last decade in terms of publication year,journals,countries/regions,organizations,references,and keywords,to investigate the current research international trends and hot topics in this area.METHODS:Bibliometric analysis was conducted on 9128 articles in the Web of Science Core Collection(WoSCC;Clarivate)database.Quantitative and qualitative analysis was employed using VOSviewer(v1.6.18),Pajek(v1.0.0.0),and CiteSpace(v6.1.R2)software.RESULTS:The 9128 papers relating to glaucoma treatment were published from April 2013 to April 2023,of which 7482 articles(82%)were original research articles and 1464(18%)were review articles.The United States(2867)and Johns Hopkins University(166)were the most productive country and institution,respectively,but the University College London had the highest h-index(54).The Journal of Glaucoma was the most productive and Ophthalmology had the highest h-index compared with other journals.The Keywords of interest included treatment surgery,cyclophotocoagulation,minimally invasive glaucoma surgery(MIGS),trabeculectomy,baerveldt,epidemiology,medication adherence,nanoparticle,optical coherence tomography(OCT),gene therapy,and artificial intelligence(AI).Glaucoma surgery appeared as a current research hotspot through the analysis of keywords.CONCLUSION:This study provides insights into the research trends and potential research hotspots in the treatment of glaucoma.This will help researchers to evaluate research policies and to promote international cooperation.
基金Supported by Shanghai Agriculture Applied Technology Development Program (Grant No.T20220120).
文摘[Objectives]This study was conducted to establish a quantitative assessment method for the textural quality of chieh-qua fruit.[Methods]Using two modes of a texture analyzer,namely TPA(texture profile analysis)and puncture,the index data of the fruit were obtained by setting different trigger forces,deformation levels,test speeds,as well as puncture speeds and puncture depths.The data included TPA hardness,adhesiveness,springiness,cohesiveness,gumminess,chewiness,resilience,as well as skin hardness,skin toughness,flesh hardness,fracturability,and compactness.[Results]Different deformation levels had a significant impact on all parameters.Hardness,adhesiveness,gumminess and chewiness showed a trend of first increasing and then decreasing with the deformation level increasing.When the deformation level was 30%,the adhesiveness,gumminess and chewiness reached their maximum values.When the deformation level was 50%,TPA hardness reached its maximum.When the compression speed was 3 mm/s,the measured values of TPA hardness,adhesiveness,chewiness,and resilience were at their maximums.The skin hardness varied significantly under different trigger forces.When the trigger force was 15 g,the skin hardness reached a maximum value of 944.63 g,and the skin toughness,flesh hardness,fracturability,and compactness also reach their maximum values respectively.When the puncture depth was 12 mm,the flesh hardness and skin toughness reached their maximums of 682.51 g and 1.82 mm,respectively.In the TPA mode,the flesh hardness of chieh-qua showed an extremely significant negative correlation with springiness,cohesiveness,and resilience(P<0.01).The fruit fracturability detected by puncture had an extremely significant positive correlation with compactness(P<0.01).[Conclusions]The evaluation method for measuring chieh-qua texture by combining TPA and the puncture mode could accurately and quantitatively reflect the differences in the flesh texture quality of chieh-qua.The optimal parameters for texture measurement of chieh-qua fruit were determined as a 15 g trigger force with 50%deformation and a 3 mm/s compression speed in TPA mode,and a 15 g trigger force with a 12 mm puncture depth in puncture mode.Puncture speed was found to have no significant effect on the texture indices of chieh-qua.
