Optical tweezers technology has the characteristics of noncontact manipulation in three dimensions and steerable separation in solutions,and could be applied to obtain a separated sperm with high quality for intracyto...Optical tweezers technology has the characteristics of noncontact manipulation in three dimensions and steerable separation in solutions,and could be applied to obtain a separated sperm with high quality for intracytoplasmic sperm injection(ICSI).However,the effects of optical tweezers on sperm motility are still unclear.To elucidate the effects on sperm motility for optical tweezers,we systematically investigated the correlation between motility parameters and the parameters of optical tweezers(wavelength,power,trapping duration,and trapping orientation).Under three systems of optical tweezers with different laser wavelengths(1064,850,and 785 nm),the nine motility parameters of free swimming were mainly affected by trapping orientation(vertical/horizontal)and trapping duration.When 850 nm laser and 1064 nm laser are used,vertical trapping significantly reduces sperm free-swimming capability with prolonged exposure time,whereas horizontal trapping exhibits relatively minor interference on sperm motility.Notably,the 785 nm laser does not induce statistically significant changes in key parameters of sperm motility under any experimental conditions(trapping orientation and duration).For the rolling frequency of trapped sperm,horizontal trapping for three wavelengths has a negligible effect compared with vertical trapping,especially for the 785 nm laser.In conclusion,horizontal trapping can preserve sperm motility under low power(below 140mW at 1064 nm,below 100mW at 850nm,below 60mW at 785 nm)and short duration(below 4 min).This trapping duration is suffcient for the separation procedure of single live sperm in ICSI.This study provides critical parameter optimization guidelines for the safe application of optical tweezers technology in reproductive medicine.展开更多
The development of electrocatalysts that both work effectively at industrial current density and resist chloride ion(Cl^(-))corrosion remains a key challenge for hydrogen production from Cl^(-)-rich alkaline water.Her...The development of electrocatalysts that both work effectively at industrial current density and resist chloride ion(Cl^(-))corrosion remains a key challenge for hydrogen production from Cl^(-)-rich alkaline water.Herein,we report a CrO_(x)-engineered nickel-based oxide catalyst(FeCoCrO_(x)/NF)that achieves exceptional activity and stability through a dual-functional interfacial mechanism.Combing in situ Raman spectroscopy,18O isotopic labeling,and electrochemical analysis,we demonstrate that the oxygen evolution reaction follows a lattice oxygen-mediated mechanism.The CrO_(x)layer selectively adsorbs hydroxide ions,forming a dynamic interfacial barrier that electrostatically repels Cl^(-)ingress,thereby mitigating Cl^(-)corrosion.Through enthalpy-based analysis,we demonstrate that electronic redistribution via Cr-O-Fe bonding increases the vacancy formation energy of Fe,thereby suppressing its dissolution.In alkaline electrolyte containing 0.5 M Cl^(-)(1.0 M KOH),the catalyst is operating continuously for 1400 h at an industrial current density of 1000 mA cm^(-2).Furthermore,the catalyst retains 99.5%of its initial activity under fluctuating current density(100-1000 mA cm^(-2)),demonstrating robustness required for industrial electrolyzers.This study establishes a paradigm for designing corrosion-resistant electrocatalysts through the synergistic modulation of interfacial ion selectivity and bulk lattice oxygen activation,advancing the application of green hydrogen production in Cl^(-)-rich alkaline water.展开更多
Precise control and measurement of nanoparticles using low-power optical tweezers are pivotal for advancing single-particle analysis,nanoscale sensing,and energy transport research.In this work,we present the tipassis...Precise control and measurement of nanoparticles using low-power optical tweezers are pivotal for advancing single-particle analysis,nanoscale sensing,and energy transport research.In this work,we present the tipassisted nanoparticle capture system that simultaneously achieves localized temperature probing and nanoparticle trapping,significantly lowering the required laser power input.Unlike traditional metal-tip plasmonic techniques that predominantly rely on intense electric field gradients,our approach employs a silicon nanotip under resonant laser excitation,uniquely integrating optical forces,thermophoretic forces,and interatomic interactions for stable nanoparticle confinement.This synergistic collaboration mechanism enables approximately a 42%reduction in laser power density compared to conventional bowtie nanoaperture methods.This experimental method achieved direct and simultaneous Raman-based measurements of localized thermal dynamics,providing new insights into nanoscale thermodynamics during optical trapping.Additionally,the silicon nanotip demonstrates reduced thermal transport due to its confined nanoscale geometry,aligning closely with our theoretical predictions.Our integrated strategy of efficient nanoparticle manipulation coupled with precise thermal probing not only enhances overall energy efficiency but also broadens the scope of potential applications in cutting-edge nanoscience and nanotechnology.展开更多
The atomically thin nature of two-dimensional(2D)layered materials makes them susceptible to charge trapping by randomly created disorders,adversely affecting carrier dynamics such as charge transport and exciton life...The atomically thin nature of two-dimensional(2D)layered materials makes them susceptible to charge trapping by randomly created disorders,adversely affecting carrier dynamics such as charge transport and exciton lifetime.Typically,these disorders lead to poor device performance or require additional space to mitigate performance degradation.In this study,we investigate 2D layered Dion–Jacobson(DJ)-phase oxide perovskite nanosheets,which exhibit charge trapping within their well-defined quantum well(QW)structures,resulting in unique tailoring of electrical conductivity and photoconductivity.These DJ-phase perovskites,composed of tunable atomic constituents,demonstrate resonant tunneling and anomalous charge trapping due to their ultra-clean QWs.Remarkably,the conductivity of insulating HSr_(2)Nb_(3)O_(10)(HSNO)increased over 1000 times upon applying voltage without additional treatments.We observed persistent photoconductivity in 2D vertical heterostructure devices,attributed to charge trapping in QWs,and demonstrated artificial synaptic behaviours in a single flake with tailored energy consumption.Varying the number of perovskite layers significantly allows the tunability of the energy bandgap.This study also highlights the high tunability of 2D perovskite nanosheets,promising various applications,including magnetic,high-k dielectric,and resistive switching devices.Our findings suggest a new class of ionic layered materials with great potential as novel two-dimensional building blocks for device applications.展开更多
The generation of economically valuable chemicals through electrocatalytic CO_(2)reduction reaction(CO_(2)RR)is a highly attractive strategy for achieving the carbon cycle.Bismuth(Bi)is a prospective element due to th...The generation of economically valuable chemicals through electrocatalytic CO_(2)reduction reaction(CO_(2)RR)is a highly attractive strategy for achieving the carbon cycle.Bismuth(Bi)is a prospective element due to the high selectivity for formate.Researches demonstrate the Bi–O bonds have a significant effect on the key*OCHO intermediate.Herein,we report a F-doped catalyst that displays remarkable performance in generating formate in pH-universal electrolytes.Specifically,the as-prepared F-Bi/BOC@GO achieves formate Faradaic efficiencies(FEformate)around 95%in a wide range of pH from 1 to 13.6.Furthermore,at an industrial level,current density of 200 mA cm^(-2),the F-Bi/BOC@GO catalyst shows a much more stable FE_(formate)than the catalyst without introducing F.In situ Raman reveals that the doped F can greatly improve the stability of Bi–O bonds during the electroreduction process.DFT calculations further demonstrate that fluorine doping raises the energy barrier for oxygen desorption from Bi–O motifs,thus enhancing the stability of active sites.Combined with X-ray photoelectron spectroscopy(XPS),the doped F acts as an electron trapping,which may direct electrons towards Bi–Bi bonds,thus protecting the key Bi–O motif.This work reveals the critical role of fluorine in stabilizing Bi–O active centers across a wide pH range,maintaining high formate Faradaic efficiency for a longer time than the catalyst without fluorine introduction.展开更多
The launch of International Thermonuclear Experimental Reactor project paves the way to wide adoption of DT fusion energy as future energy source.Efficient fuel cycle to minimize strategic tritium inventory proves cru...The launch of International Thermonuclear Experimental Reactor project paves the way to wide adoption of DT fusion energy as future energy source.Efficient fuel cycle to minimize strategic tritium inventory proves crucial for commercially viable fusion technologies.ZrCo alloy is considered as a promising candidate for fast isotope handling.However,cycling degradation caused by hydrogen-induced disproportionation results in severe tritium trapping,thus impeding its practical application.Herein,an isostructural transition is successfully constructed with low hysterisis,ameliorated plateau flatness of pressure-composition isotherms and improved high-temperature durability for hydrogen trapping minimization.Specifically,the optimal Zr_(0.7)Hf_(0.15)Nb_(0.15)Co_(0.6)Cu_(0.15)Ni_(0.25) alloy adopts Hf-Nb and Cu-Ni as Zr and Co side doping elements,exhibiting substantial thermodynamic destabilization with nearly 90℃ reduction of delivery temperature,and significant kinetic promotion with a threefold lower energy barrier.More importantly,both hydrogen utilization and cycling retention of optimal alloy are increased by about twenty times compared with pristine alloy after 100 cycles at 500℃.Minimized disproportionation driving force from both isostructural transition and suppressed 8e hydrogen occupation realizes full potential of optimal alloy.This work demonstrates the effectiveness of combining isostructural transformation and high-temperature durability improvement to enhance the hydrogen utilization of ZrCo-based alloys and other hydrogen storage materials.展开更多
[Objective] To evaluate the control effect of yellow sticky cards and sex pheromone on Plutella xylostella and Liriomyza spp.,which can provide reference for large area extension of the technique.[Method] The integrat...[Objective] To evaluate the control effect of yellow sticky cards and sex pheromone on Plutella xylostella and Liriomyza spp.,which can provide reference for large area extension of the technique.[Method] The integrated assessment of trapping efficiency of colored sticky cards and sex pheromone on Liriomyza spp.and Plutella xylostella was conducted by field surveys and structured interview in Tonghai County,Yunnan Province,China.[Result] The results showed that yellow sticky cards and sex pheromone have strong power of trapping Liriomyza spp.and Plutella xylostella（3 414±720 and（219±157） head/piece,respectively）;the control cost by the usage of pesticide is the highest,（10 099.5±2 752.5） yuan/hm^2,yellow sticky cards and sex pheromone takes the second place,（1 125.0±465.0） yuan/hm^2,the control cost by the usage of yellow sticky cards is the lowest,（450.0 ±186.0）yuan/hm^2.Without the usage of yellow sticky cards and sex pheromone,pesticide application times and costs are（15.0±2.7） times and（12 070.5±2 136.0） yuan/hm^2;combined with usage of yellow sticky cards and sex pheromone,pesticide application times and costs reduce by 5.7 times and 4 618.5 yuan/hm^2.The ratio of trapped beneficial insects and target pests was 1 ∶1 131,which showed that the negative effect of yellow sticky cards and sex pheromone on the non-target insects was very limited.[Conclusion] The trapping approach has become popular among all the local farmers.Looking at the above factors,the trapping technology has strong application prospect and promotion value in pest control field.展开更多
Activation of neutrophil membrane receptors initiates intracellular signal transduction cascades that orchestrate the cell's effector functions,including phagocytosis,production of reactive oxygen and halogen spec...Activation of neutrophil membrane receptors initiates intracellular signal transduction cascades that orchestrate the cell's effector functions,including phagocytosis,production of reactive oxygen and halogen species,degranulation,and NETosis(formation of neutrophil extracellular traps[NETs]).NETs,which contain antimicrobial compounds such as myeloperoxidase(MPO),represent a strategy to combat infection.However,excessive production of NETs promotes thrombosis,diabetes mellitus,and other diseases.Therefore,investigations into the mechanisms of NETosis and the identification of modulators of this process are critical for developing strategies to address NETosis-related disorders.Here,we identified a novel NETosis inducer,human serum albumin(HSA)modified by the MPO product hypochlorous acid(HSAHOCl),whose accumulation in vivo was correlated with inflammatory processes.Using human blood neutrophils,we investigated HSAHOCl-induced NETosis and detected NET formation by flow cytometry.The results showed that the mechanism of HSAHOClinduced NETosis involved MPO,NADPH oxidase,and phosphatidylinositol 3-kinases(PI3Ks),and that HSAHOCl activated a reactive oxygen species-dependent suicidal type of NETosis.Moreover,HSAHOCl-induced NETosis was inhibited by an anti-HSAHOCl monoclonal antibody.Thus,our findings may facilitate the development of strategies to modulate NETosis in inflammation associated with elevated MPO activity.展开更多
Nest predation is a critical driver of avian reproductive success,yet its response to urbanization remains controversial.Using infrared camera traps to monitor 133 artificial nests and 32 natural nests of the Spotted ...Nest predation is a critical driver of avian reproductive success,yet its response to urbanization remains controversial.Using infrared camera traps to monitor 133 artificial nests and 32 natural nests of the Spotted Dove(Spilopelia chinensis) along an urbanization gradient in Nanchang and Shangrao,China,from 2021 to 2023,we examined spatiotemporal variation in predation pressure.We deconstructed predation pressure into risk(nest fate and survival time) and pattern(predation frequency,predator size,and predator-nest interaction duration).We found that higher urbanization and better nest concealment significantly reduced predation risk.The composition of the predator community did not change along the urbanization gradient,suggesting that the reduced nest predation risk in cities is likely driven by behavioral factors,such as the availability of alternative food or human shield effect,rather than by the filtering of predator species.In contrast,predation patterns were primarily moderated by season.The off-peak breeding season was char acterized by more frequent but less severe predation events involving smaller predators and had shorter predator-nest interaction durations compared to the peak season.This seasonal shift opens a breeding window during the off-peak season,when lethal nest predation risk is reduced.The Spotted Dove's unique life-history traits enable it to capitalize on this opportunity by balancing environmental costs,enhancing its reproductive success and facilitating its colonization of urban environments.展开更多
Dissolution trapping is one of the most promising mechanisms for safe geological carbon storage.Density-driven convection substantially accelerates the conversion of free-phase CO_(2)to the dissolved state,enhancing t...Dissolution trapping is one of the most promising mechanisms for safe geological carbon storage.Density-driven convection substantially accelerates the conversion of free-phase CO_(2)to the dissolved state,enhancing the sequestration safety.Since this process occurs on time scales of hundreds to thousands of years,reproducing it through conventional laboratory physical model tests is challenging.The hypergravity experiment reduces the model size and shortens the experimental time,enabling the modeling of gravity-driven flow processes at the field scale.However,it is uncertain whether the preferential flow effect caused by fractures can be reproduced in a hypergravity experiment.In this study,a three-dimensional discrete fracture-matrix model(3D-DFM)was used to evaluate the feasibility of hypergravity experiment of the transport of dissolved CO_(2)in fractured reservoirs.Numerical hypergravity tests were performed to examine the feasibility of modeling density-driven convection in homogeneous and heterogeneous media at different centrifuge accelerations.The hypergravity experiment can be used to study density-driven convection of dissolved CO_(2)at the field scale in homogeneous system.The numerical results show that the hypergravity experiment enables a faster breakthrough of plume and overestimates CO_(2)migration in the matrix surrounding the fractures.展开更多
In recent years,microfluidic technology has emerged as a powerful and innovative tool,attracting significant attention for its ability to provide real-time visualization of CO_(2)flow,mass transfer,and reaction proces...In recent years,microfluidic technology has emerged as a powerful and innovative tool,attracting significant attention for its ability to provide real-time visualization of CO_(2)flow,mass transfer,and reaction processes in porous media.This review examines the application of microfluidic technology in CO_(2)sequestration in saline aquifers,emphasizing the advantages of saline aquifer for geological sequestration,including safety,high storage capacity,stability,and cost-effectiveness.The materials used for microfluidic chips and the design of microchannels are systematically reviewed,offering forward-looking recommendations for chip selection and microchannel characterization in future research on CO_(2)sequestration in saline aquifer.Based on a detailed analysis of advancements in microfluidic technology,this review highlights key findings related to CO_(2)trapping mechanisms,salt precipitation,and CO_(2)-water-rock chemical interactions within saline aquifers.Although microfluidic technology shows great promise in these areas,this review identifies limitations in current studies and outlines future research directions,aiming to promote further innovation and broader application of microfluidic technology in the field of CO_(2)sequestration in saline aquifer.展开更多
Owing to the presence of a low-energy,long-lived nuclear isomeric state,^(229)Th is an ideal candidate for developing the next generation clock—the nuclear clock—holding great promise for both applied and fundamenta...Owing to the presence of a low-energy,long-lived nuclear isomeric state,^(229)Th is an ideal candidate for developing the next generation clock—the nuclear clock—holding great promise for both applied and fundamental physics.The^(229)Th ionic nuclear optical clock has garnered considerable attention,attributed to its high precision with a relative uncertainty of≤1.5×10^(-19)and the potential for common-mode noise cancellation via self-comparison between the nuclear transition and the electronic transition of thorium ions.In this article,we focus on Th^(n+)ions(n=1,2,3)and present a comprehensive review of the current progress in the development of ionic nuclear clocks,covering essential steps such as ion generation,trapping,and cooling.Furthermore,we discuss the realization of a closed-loop clock cycle,addressing key aspects including stable isomer excitation and efficient isomer deexcitation.展开更多
Doping metal ions offer a promising strategy to tune the intrinsic and surface properties of BiVO_(4)for enhanced photoelectrochemical(PEC)activity.Given this,experimental and theoretical studies on cadmium(Cd)doping ...Doping metal ions offer a promising strategy to tune the intrinsic and surface properties of BiVO_(4)for enhanced photoelectrochemical(PEC)activity.Given this,experimental and theoretical studies on cadmium(Cd)doping to BiVO_(4)photoanode were studied for PEC water splitting applications.The spectroscopic and PEC results indicate that the substitution of Cd at Bi lattice sites causes the reduction in the valence state of V^(5+)to V4+that creates hole trap states below the Fermi level of BiVO_(4).The introduced hole trap states at the BiVO_(4)surface suppress the charge recombination and provide effective hole transfer sites for the facile water oxidation reactions.The CdBiVO_(4)exhibited significantly higher photocurrent compared to the pristine BiVO_(4)reaching 3.5 mA cm^(-2)(with a hole scavenger)at 1.23 V vs RHE.Furthermore,doping increases the carrier density in the bulk of BiVO_(4)leading to improved charge separation,and charge transfer while reducing the hole transfer resistance at the interface.The Cd-doped BiVO_(4)exhibited a charge separation efficiency of 80%and with a 90%of overall water splitting faradaic efficiency.Importantly,the results of this work propose the advantages of doping metal ions at Bi lattice sites in BiVO_(4)for improved PEC activity.展开更多
Neutrophil extracellular traps(NETs)have emerged as key mediators of cardiovascular diseases(CVDs),linking innate immune activation to vascular injury,thrombosis,and maladaptive remodeling.This review synthesizes rece...Neutrophil extracellular traps(NETs)have emerged as key mediators of cardiovascular diseases(CVDs),linking innate immune activation to vascular injury,thrombosis,and maladaptive remodeling.This review synthesizes recent insights into the molecular and cellular pathways driving NET formation,including post-translational modifications,metabolic reprogramming,inflammasome signaling,and autophagy.It highlights the role of NETs in atherosclerosis,thrombosis,myocardial ischemia-reperfusion injury,and hypertension,emphasizing common control points such as peptidylarginine deiminase 4(PAD4)-dependent histone citrullination and nicotinamide adenine dinucleotide phosphate oxidases 2(NOX2)-mediated oxidative stress.Mechanistic interpretation of circulating biomarkers,includingmyeloperoxidase(MPO)-DNA complexes,citrullinated histoneH3,and cell-free DNA,provides a translational bridge between NET biology and patient stratification.Therapeutic strategies targeting NETs are examined through three main approaches:inhibition of NET initiation,enhancement of chromatin clearance,and neutralization of toxic extracellular components,with attention to both established and emerging interventions.In contrast to previous reviews,this study highlights the novelty of a mechano-therapeutic framework by providing a mechanistic roadmap linking NET formation pathways to therapeutic targeting in cardiovascular disease.Moving forward,integrating mechanistic information with biomarker discovery,precision profiling,and targeted therapies offers innovative strategies to reduce vascular inflammation and improve outcomes in cardiovascular disease.展开更多
Self-trapped excitons(STEs),known for their unique radiative properties,have been harnessed in diverse photonic devices;however,their comprehensive understanding and manipulation remain elusive.In this study,we presen...Self-trapped excitons(STEs),known for their unique radiative properties,have been harnessed in diverse photonic devices;however,their comprehensive understanding and manipulation remain elusive.In this study,we present novel experimental and theoretical evidence revealing the hybrid nature and optical tunability of STE state in Cs_(2)Ag_(0.4)Na_(0.6)InCl_(6).The detection of the Fano resonance in laser energy-dependent Raman and photoluminescence spectra indicates the emergence of an exciton-phonon hybrid state,arising from robust quantum interference between the discrete phonon and continuum exciton states.Moreover,we demonstrate continuous tuning of this hybrid state with the energy and intensity of the laser field.These findings lay the foundation for a comprehensive understanding of the nature of STE and their potential for state control.展开更多
A 2D electron-longitudinal-acoustic-phonon interaction Hamiltonian is derived and used to calculate the groundstate energy of the acoustic polarons in two dimensions. The numerical results for the ground-state energy ...A 2D electron-longitudinal-acoustic-phonon interaction Hamiltonian is derived and used to calculate the groundstate energy of the acoustic polarons in two dimensions. The numerical results for the ground-state energy of the acoustic polarons in two and three dimensions are obtained. The 3D results agree with those obtained by using the Feynman path-integral approach. It is found that the critical coupling constant of the transition from the quasifree state to the self-trapped state in the 2D case is much smaller than in the 3D case for a given cutoff wave-vector. The theory has been used to judge the possibility of the self-trapping for several real materials. The results indicate that the self-trappings of the electrons in AlN and the holes in AlN and GaN are expected to be observed in 2D systems.展开更多
The applicability of Ce and Y as promising candidate elements to form irreversible traps in weld metal was investigated by thermal desorption spectroscopy(TDS) with gas chromatography(GC). The precise nature of the pr...The applicability of Ce and Y as promising candidate elements to form irreversible traps in weld metal was investigated by thermal desorption spectroscopy(TDS) with gas chromatography(GC). The precise nature of the precipitate particles newly formed in the weld metal by the addition of Ce and Y to a certain alloy system was characterized. Moreover,the hydrogen trapping efficiency expressed as the reduction of the diffusible hydrogen in the weld metal was analyzed. The results showed that the addition of Ce and/or Y to this alloy system led to the formation of a mixed type of(Ce,Ti)-based oxide,(Y,Ni)-based carbide,or(Ce,Y,Ti)-based oxide particles. Because of the high activation energy of the mixed type of particles(≥ 150 k J/mol),the trapping efficiency for hydrogen was considered to be sufficiently high to effectively reduce the diffusible hydrogen content.展开更多
Photoelectron is the foundation of latent image formation, the decay process of photoelectrons is influenced by all kinds of trapping centres in silver halide. By analysing the mechanism of latent image formation it i...Photoelectron is the foundation of latent image formation, the decay process of photoelectrons is influenced by all kinds of trapping centres in silver halide. By analysing the mechanism of latent image formation it is found that electron trap, hole trap, and one kind of recombination centre where free electron and trapped hole recombine are the main trapping centres in silver halide. Different trapping centres have different influences on the photoelectron behaviour. The effects of all kinds of typical trapping centres on the decay of photoelectrons are systematically investigated by solving the photoelectron decay kinetic equations. The results are in agreement with those obtained in the microwave absorption dielectric spectrum experiment.展开更多
基金supported by the Natural Science Foundation of Anhui Province in China(2508085MF166)Research Fund of Anhui Institute of Translational Medicine(2024zh-03)+2 种基金Key Scientific Research Foundation of Education Department of Anhui Province(2023AH040083)National Natural Science Foundation of China(12404353)Cultivation Project of Training Young and Middle-aged Teachers in Universities of Anhui Province(DTR2023013).
文摘Optical tweezers technology has the characteristics of noncontact manipulation in three dimensions and steerable separation in solutions,and could be applied to obtain a separated sperm with high quality for intracytoplasmic sperm injection(ICSI).However,the effects of optical tweezers on sperm motility are still unclear.To elucidate the effects on sperm motility for optical tweezers,we systematically investigated the correlation between motility parameters and the parameters of optical tweezers(wavelength,power,trapping duration,and trapping orientation).Under three systems of optical tweezers with different laser wavelengths(1064,850,and 785 nm),the nine motility parameters of free swimming were mainly affected by trapping orientation(vertical/horizontal)and trapping duration.When 850 nm laser and 1064 nm laser are used,vertical trapping significantly reduces sperm free-swimming capability with prolonged exposure time,whereas horizontal trapping exhibits relatively minor interference on sperm motility.Notably,the 785 nm laser does not induce statistically significant changes in key parameters of sperm motility under any experimental conditions(trapping orientation and duration).For the rolling frequency of trapped sperm,horizontal trapping for three wavelengths has a negligible effect compared with vertical trapping,especially for the 785 nm laser.In conclusion,horizontal trapping can preserve sperm motility under low power(below 140mW at 1064 nm,below 100mW at 850nm,below 60mW at 785 nm)and short duration(below 4 min).This trapping duration is suffcient for the separation procedure of single live sperm in ICSI.This study provides critical parameter optimization guidelines for the safe application of optical tweezers technology in reproductive medicine.
基金supported by the National Nature Science Foundation of China under Grant No.22269021the Tianshan Talent Project of Xinjiang Uygur Autonomous Region:2023TSYCQNTJ0039the Open project of Key Laboratory in Xinjiang Uygur Autonomous Region of China:2023D04027。
文摘The development of electrocatalysts that both work effectively at industrial current density and resist chloride ion(Cl^(-))corrosion remains a key challenge for hydrogen production from Cl^(-)-rich alkaline water.Herein,we report a CrO_(x)-engineered nickel-based oxide catalyst(FeCoCrO_(x)/NF)that achieves exceptional activity and stability through a dual-functional interfacial mechanism.Combing in situ Raman spectroscopy,18O isotopic labeling,and electrochemical analysis,we demonstrate that the oxygen evolution reaction follows a lattice oxygen-mediated mechanism.The CrO_(x)layer selectively adsorbs hydroxide ions,forming a dynamic interfacial barrier that electrostatically repels Cl^(-)ingress,thereby mitigating Cl^(-)corrosion.Through enthalpy-based analysis,we demonstrate that electronic redistribution via Cr-O-Fe bonding increases the vacancy formation energy of Fe,thereby suppressing its dissolution.In alkaline electrolyte containing 0.5 M Cl^(-)(1.0 M KOH),the catalyst is operating continuously for 1400 h at an industrial current density of 1000 mA cm^(-2).Furthermore,the catalyst retains 99.5%of its initial activity under fluctuating current density(100-1000 mA cm^(-2)),demonstrating robustness required for industrial electrolyzers.This study establishes a paradigm for designing corrosion-resistant electrocatalysts through the synergistic modulation of interfacial ion selectivity and bulk lattice oxygen activation,advancing the application of green hydrogen production in Cl^(-)-rich alkaline water.
基金supported by the National Natural Science Foundation of China(Grant No.52206107)the National Key R&D Program of China(Grant No.2023YFE0120200)。
文摘Precise control and measurement of nanoparticles using low-power optical tweezers are pivotal for advancing single-particle analysis,nanoscale sensing,and energy transport research.In this work,we present the tipassisted nanoparticle capture system that simultaneously achieves localized temperature probing and nanoparticle trapping,significantly lowering the required laser power input.Unlike traditional metal-tip plasmonic techniques that predominantly rely on intense electric field gradients,our approach employs a silicon nanotip under resonant laser excitation,uniquely integrating optical forces,thermophoretic forces,and interatomic interactions for stable nanoparticle confinement.This synergistic collaboration mechanism enables approximately a 42%reduction in laser power density compared to conventional bowtie nanoaperture methods.This experimental method achieved direct and simultaneous Raman-based measurements of localized thermal dynamics,providing new insights into nanoscale thermodynamics during optical trapping.Additionally,the silicon nanotip demonstrates reduced thermal transport due to its confined nanoscale geometry,aligning closely with our theoretical predictions.Our integrated strategy of efficient nanoparticle manipulation coupled with precise thermal probing not only enhances overall energy efficiency but also broadens the scope of potential applications in cutting-edge nanoscience and nanotechnology.
基金supported by the National Research Foundation of Korea(NRF)grant funded by the government of the Republic of Korea(the Ministry of Science and ICT)(Nos.NRF-2023R1A2C2003247,2021R1C1C2091728,and 2021R1A2C2010695)the Nano&Material Technology Development Program through the National Research Foundation of Korea(NRF)funded by Ministry of Science and ICT(No.RS-2024-00402972)the National Research Council of Science&Technology(NST)grant by the Korea。
文摘The atomically thin nature of two-dimensional(2D)layered materials makes them susceptible to charge trapping by randomly created disorders,adversely affecting carrier dynamics such as charge transport and exciton lifetime.Typically,these disorders lead to poor device performance or require additional space to mitigate performance degradation.In this study,we investigate 2D layered Dion–Jacobson(DJ)-phase oxide perovskite nanosheets,which exhibit charge trapping within their well-defined quantum well(QW)structures,resulting in unique tailoring of electrical conductivity and photoconductivity.These DJ-phase perovskites,composed of tunable atomic constituents,demonstrate resonant tunneling and anomalous charge trapping due to their ultra-clean QWs.Remarkably,the conductivity of insulating HSr_(2)Nb_(3)O_(10)(HSNO)increased over 1000 times upon applying voltage without additional treatments.We observed persistent photoconductivity in 2D vertical heterostructure devices,attributed to charge trapping in QWs,and demonstrated artificial synaptic behaviours in a single flake with tailored energy consumption.Varying the number of perovskite layers significantly allows the tunability of the energy bandgap.This study also highlights the high tunability of 2D perovskite nanosheets,promising various applications,including magnetic,high-k dielectric,and resistive switching devices.Our findings suggest a new class of ionic layered materials with great potential as novel two-dimensional building blocks for device applications.
基金supported by the National Natural Science Foundation of China(22322805,22178104,U22B20143,U24A20546)Shanghai Municipal Science and Technology Major Project+1 种基金the Shanghai Scientific and Technological Innovation Project(22dz1205900)the Fundamental Research Funds for the Central Universities,and Shanghai Rising-Star Program(23QA1402200)。
文摘The generation of economically valuable chemicals through electrocatalytic CO_(2)reduction reaction(CO_(2)RR)is a highly attractive strategy for achieving the carbon cycle.Bismuth(Bi)is a prospective element due to the high selectivity for formate.Researches demonstrate the Bi–O bonds have a significant effect on the key*OCHO intermediate.Herein,we report a F-doped catalyst that displays remarkable performance in generating formate in pH-universal electrolytes.Specifically,the as-prepared F-Bi/BOC@GO achieves formate Faradaic efficiencies(FEformate)around 95%in a wide range of pH from 1 to 13.6.Furthermore,at an industrial level,current density of 200 mA cm^(-2),the F-Bi/BOC@GO catalyst shows a much more stable FE_(formate)than the catalyst without introducing F.In situ Raman reveals that the doped F can greatly improve the stability of Bi–O bonds during the electroreduction process.DFT calculations further demonstrate that fluorine doping raises the energy barrier for oxygen desorption from Bi–O motifs,thus enhancing the stability of active sites.Combined with X-ray photoelectron spectroscopy(XPS),the doped F acts as an electron trapping,which may direct electrons towards Bi–Bi bonds,thus protecting the key Bi–O motif.This work reveals the critical role of fluorine in stabilizing Bi–O active centers across a wide pH range,maintaining high formate Faradaic efficiency for a longer time than the catalyst without fluorine introduction.
基金supports from the National Key Research and Development Program of China(2022YFE03170002)the National Natural Science Foundation of China(52071286 and U2030208).
文摘The launch of International Thermonuclear Experimental Reactor project paves the way to wide adoption of DT fusion energy as future energy source.Efficient fuel cycle to minimize strategic tritium inventory proves crucial for commercially viable fusion technologies.ZrCo alloy is considered as a promising candidate for fast isotope handling.However,cycling degradation caused by hydrogen-induced disproportionation results in severe tritium trapping,thus impeding its practical application.Herein,an isostructural transition is successfully constructed with low hysterisis,ameliorated plateau flatness of pressure-composition isotherms and improved high-temperature durability for hydrogen trapping minimization.Specifically,the optimal Zr_(0.7)Hf_(0.15)Nb_(0.15)Co_(0.6)Cu_(0.15)Ni_(0.25) alloy adopts Hf-Nb and Cu-Ni as Zr and Co side doping elements,exhibiting substantial thermodynamic destabilization with nearly 90℃ reduction of delivery temperature,and significant kinetic promotion with a threefold lower energy barrier.More importantly,both hydrogen utilization and cycling retention of optimal alloy are increased by about twenty times compared with pristine alloy after 100 cycles at 500℃.Minimized disproportionation driving force from both isostructural transition and suppressed 8e hydrogen occupation realizes full potential of optimal alloy.This work demonstrates the effectiveness of combining isostructural transformation and high-temperature durability improvement to enhance the hydrogen utilization of ZrCo-based alloys and other hydrogen storage materials.
基金Supported by Development Program of Misereor Foundation of Germany(335-0311028Z)~~
文摘[Objective] To evaluate the control effect of yellow sticky cards and sex pheromone on Plutella xylostella and Liriomyza spp.,which can provide reference for large area extension of the technique.[Method] The integrated assessment of trapping efficiency of colored sticky cards and sex pheromone on Liriomyza spp.and Plutella xylostella was conducted by field surveys and structured interview in Tonghai County,Yunnan Province,China.[Result] The results showed that yellow sticky cards and sex pheromone have strong power of trapping Liriomyza spp.and Plutella xylostella（3 414±720 and（219±157） head/piece,respectively）;the control cost by the usage of pesticide is the highest,（10 099.5±2 752.5） yuan/hm^2,yellow sticky cards and sex pheromone takes the second place,（1 125.0±465.0） yuan/hm^2,the control cost by the usage of yellow sticky cards is the lowest,（450.0 ±186.0）yuan/hm^2.Without the usage of yellow sticky cards and sex pheromone,pesticide application times and costs are（15.0±2.7） times and（12 070.5±2 136.0） yuan/hm^2;combined with usage of yellow sticky cards and sex pheromone,pesticide application times and costs reduce by 5.7 times and 4 618.5 yuan/hm^2.The ratio of trapped beneficial insects and target pests was 1 ∶1 131,which showed that the negative effect of yellow sticky cards and sex pheromone on the non-target insects was very limited.[Conclusion] The trapping approach has become popular among all the local farmers.Looking at the above factors,the trapping technology has strong application prospect and promotion value in pest control field.
文摘Activation of neutrophil membrane receptors initiates intracellular signal transduction cascades that orchestrate the cell's effector functions,including phagocytosis,production of reactive oxygen and halogen species,degranulation,and NETosis(formation of neutrophil extracellular traps[NETs]).NETs,which contain antimicrobial compounds such as myeloperoxidase(MPO),represent a strategy to combat infection.However,excessive production of NETs promotes thrombosis,diabetes mellitus,and other diseases.Therefore,investigations into the mechanisms of NETosis and the identification of modulators of this process are critical for developing strategies to address NETosis-related disorders.Here,we identified a novel NETosis inducer,human serum albumin(HSA)modified by the MPO product hypochlorous acid(HSAHOCl),whose accumulation in vivo was correlated with inflammatory processes.Using human blood neutrophils,we investigated HSAHOCl-induced NETosis and detected NET formation by flow cytometry.The results showed that the mechanism of HSAHOClinduced NETosis involved MPO,NADPH oxidase,and phosphatidylinositol 3-kinases(PI3Ks),and that HSAHOCl activated a reactive oxygen species-dependent suicidal type of NETosis.Moreover,HSAHOCl-induced NETosis was inhibited by an anti-HSAHOCl monoclonal antibody.Thus,our findings may facilitate the development of strategies to modulate NETosis in inflammation associated with elevated MPO activity.
基金financially supported by the Jiangxi Provincial Natural Science Foundation,China (No. 20224ACB205006)。
文摘Nest predation is a critical driver of avian reproductive success,yet its response to urbanization remains controversial.Using infrared camera traps to monitor 133 artificial nests and 32 natural nests of the Spotted Dove(Spilopelia chinensis) along an urbanization gradient in Nanchang and Shangrao,China,from 2021 to 2023,we examined spatiotemporal variation in predation pressure.We deconstructed predation pressure into risk(nest fate and survival time) and pattern(predation frequency,predator size,and predator-nest interaction duration).We found that higher urbanization and better nest concealment significantly reduced predation risk.The composition of the predator community did not change along the urbanization gradient,suggesting that the reduced nest predation risk in cities is likely driven by behavioral factors,such as the availability of alternative food or human shield effect,rather than by the filtering of predator species.In contrast,predation patterns were primarily moderated by season.The off-peak breeding season was char acterized by more frequent but less severe predation events involving smaller predators and had shorter predator-nest interaction durations compared to the peak season.This seasonal shift opens a breeding window during the off-peak season,when lethal nest predation risk is reduced.The Spotted Dove's unique life-history traits enable it to capitalize on this opportunity by balancing environmental costs,enhancing its reproductive success and facilitating its colonization of urban environments.
基金the financial support from research grants provided by the National Natural Science Foundation of China(Nos.52588202,and 42277128)the National Key R&D Program of China(No.2024YFA1612400)。
文摘Dissolution trapping is one of the most promising mechanisms for safe geological carbon storage.Density-driven convection substantially accelerates the conversion of free-phase CO_(2)to the dissolved state,enhancing the sequestration safety.Since this process occurs on time scales of hundreds to thousands of years,reproducing it through conventional laboratory physical model tests is challenging.The hypergravity experiment reduces the model size and shortens the experimental time,enabling the modeling of gravity-driven flow processes at the field scale.However,it is uncertain whether the preferential flow effect caused by fractures can be reproduced in a hypergravity experiment.In this study,a three-dimensional discrete fracture-matrix model(3D-DFM)was used to evaluate the feasibility of hypergravity experiment of the transport of dissolved CO_(2)in fractured reservoirs.Numerical hypergravity tests were performed to examine the feasibility of modeling density-driven convection in homogeneous and heterogeneous media at different centrifuge accelerations.The hypergravity experiment can be used to study density-driven convection of dissolved CO_(2)at the field scale in homogeneous system.The numerical results show that the hypergravity experiment enables a faster breakthrough of plume and overestimates CO_(2)migration in the matrix surrounding the fractures.
基金supported by the National Natural Science Foundation of China(Grant Nos.U23A20671 and 12302344)the Creative Groups of Natural Science Foundation of Hubei Province,China(Grant No.2021CFA030).
文摘In recent years,microfluidic technology has emerged as a powerful and innovative tool,attracting significant attention for its ability to provide real-time visualization of CO_(2)flow,mass transfer,and reaction processes in porous media.This review examines the application of microfluidic technology in CO_(2)sequestration in saline aquifers,emphasizing the advantages of saline aquifer for geological sequestration,including safety,high storage capacity,stability,and cost-effectiveness.The materials used for microfluidic chips and the design of microchannels are systematically reviewed,offering forward-looking recommendations for chip selection and microchannel characterization in future research on CO_(2)sequestration in saline aquifer.Based on a detailed analysis of advancements in microfluidic technology,this review highlights key findings related to CO_(2)trapping mechanisms,salt precipitation,and CO_(2)-water-rock chemical interactions within saline aquifers.Although microfluidic technology shows great promise in these areas,this review identifies limitations in current studies and outlines future research directions,aiming to promote further innovation and broader application of microfluidic technology in the field of CO_(2)sequestration in saline aquifer.
基金Project supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB0920000)the National Natural Science Foundation of China(Grant No.12341401)。
文摘Owing to the presence of a low-energy,long-lived nuclear isomeric state,^(229)Th is an ideal candidate for developing the next generation clock—the nuclear clock—holding great promise for both applied and fundamental physics.The^(229)Th ionic nuclear optical clock has garnered considerable attention,attributed to its high precision with a relative uncertainty of≤1.5×10^(-19)and the potential for common-mode noise cancellation via self-comparison between the nuclear transition and the electronic transition of thorium ions.In this article,we focus on Th^(n+)ions(n=1,2,3)and present a comprehensive review of the current progress in the development of ionic nuclear clocks,covering essential steps such as ion generation,trapping,and cooling.Furthermore,we discuss the realization of a closed-loop clock cycle,addressing key aspects including stable isomer excitation and efficient isomer deexcitation.
基金the support of the Natural Sciences and Engineering Research Council of Canada(NSERC)Tier 1 Canada Research Chair in Green Hydrogen Production,the Québec Ministère de l'Économie,de l'Innovation et de l'Énergie(MEIE)[Développement de catalyseurs et d'électrodes innovants,àfaibles coûts,performants et durables pour la production d'hydrogène vert,funding reference number 00393501]。
文摘Doping metal ions offer a promising strategy to tune the intrinsic and surface properties of BiVO_(4)for enhanced photoelectrochemical(PEC)activity.Given this,experimental and theoretical studies on cadmium(Cd)doping to BiVO_(4)photoanode were studied for PEC water splitting applications.The spectroscopic and PEC results indicate that the substitution of Cd at Bi lattice sites causes the reduction in the valence state of V^(5+)to V4+that creates hole trap states below the Fermi level of BiVO_(4).The introduced hole trap states at the BiVO_(4)surface suppress the charge recombination and provide effective hole transfer sites for the facile water oxidation reactions.The CdBiVO_(4)exhibited significantly higher photocurrent compared to the pristine BiVO_(4)reaching 3.5 mA cm^(-2)(with a hole scavenger)at 1.23 V vs RHE.Furthermore,doping increases the carrier density in the bulk of BiVO_(4)leading to improved charge separation,and charge transfer while reducing the hole transfer resistance at the interface.The Cd-doped BiVO_(4)exhibited a charge separation efficiency of 80%and with a 90%of overall water splitting faradaic efficiency.Importantly,the results of this work propose the advantages of doping metal ions at Bi lattice sites in BiVO_(4)for improved PEC activity.
文摘Neutrophil extracellular traps(NETs)have emerged as key mediators of cardiovascular diseases(CVDs),linking innate immune activation to vascular injury,thrombosis,and maladaptive remodeling.This review synthesizes recent insights into the molecular and cellular pathways driving NET formation,including post-translational modifications,metabolic reprogramming,inflammasome signaling,and autophagy.It highlights the role of NETs in atherosclerosis,thrombosis,myocardial ischemia-reperfusion injury,and hypertension,emphasizing common control points such as peptidylarginine deiminase 4(PAD4)-dependent histone citrullination and nicotinamide adenine dinucleotide phosphate oxidases 2(NOX2)-mediated oxidative stress.Mechanistic interpretation of circulating biomarkers,includingmyeloperoxidase(MPO)-DNA complexes,citrullinated histoneH3,and cell-free DNA,provides a translational bridge between NET biology and patient stratification.Therapeutic strategies targeting NETs are examined through three main approaches:inhibition of NET initiation,enhancement of chromatin clearance,and neutralization of toxic extracellular components,with attention to both established and emerging interventions.In contrast to previous reviews,this study highlights the novelty of a mechano-therapeutic framework by providing a mechanistic roadmap linking NET formation pathways to therapeutic targeting in cardiovascular disease.Moving forward,integrating mechanistic information with biomarker discovery,precision profiling,and targeted therapies offers innovative strategies to reduce vascular inflammation and improve outcomes in cardiovascular disease.
基金funding support from the National Natural Science Foundation of China(Grant No.12525405)funding support from the National Natural Science Foundation of China(Grant No.12393831)the CAS Project for Young Scientists in Basic Research(Grant No.YSBR-120)。
文摘Self-trapped excitons(STEs),known for their unique radiative properties,have been harnessed in diverse photonic devices;however,their comprehensive understanding and manipulation remain elusive.In this study,we present novel experimental and theoretical evidence revealing the hybrid nature and optical tunability of STE state in Cs_(2)Ag_(0.4)Na_(0.6)InCl_(6).The detection of the Fano resonance in laser energy-dependent Raman and photoluminescence spectra indicates the emergence of an exciton-phonon hybrid state,arising from robust quantum interference between the discrete phonon and continuum exciton states.Moreover,we demonstrate continuous tuning of this hybrid state with the energy and intensity of the laser field.These findings lay the foundation for a comprehensive understanding of the nature of STE and their potential for state control.
基金Project supported by the Doctoral Program Foundation of Institutions of Higher Education China （Grant No 20040126003） and the Natural Science Foundation of Inner Mongol of China （Grant No 200408020101）.
文摘A 2D electron-longitudinal-acoustic-phonon interaction Hamiltonian is derived and used to calculate the groundstate energy of the acoustic polarons in two dimensions. The numerical results for the ground-state energy of the acoustic polarons in two and three dimensions are obtained. The 3D results agree with those obtained by using the Feynman path-integral approach. It is found that the critical coupling constant of the transition from the quasifree state to the self-trapped state in the 2D case is much smaller than in the 3D case for a given cutoff wave-vector. The theory has been used to judge the possibility of the self-trapping for several real materials. The results indicate that the self-trappings of the electrons in AlN and the holes in AlN and GaN are expected to be observed in 2D systems.
文摘The applicability of Ce and Y as promising candidate elements to form irreversible traps in weld metal was investigated by thermal desorption spectroscopy(TDS) with gas chromatography(GC). The precise nature of the precipitate particles newly formed in the weld metal by the addition of Ce and Y to a certain alloy system was characterized. Moreover,the hydrogen trapping efficiency expressed as the reduction of the diffusible hydrogen in the weld metal was analyzed. The results showed that the addition of Ce and/or Y to this alloy system led to the formation of a mixed type of(Ce,Ti)-based oxide,(Y,Ni)-based carbide,or(Ce,Y,Ti)-based oxide particles. Because of the high activation energy of the mixed type of particles(≥ 150 k J/mol),the trapping efficiency for hydrogen was considered to be sufficiently high to effectively reduce the diffusible hydrogen content.
基金Project supported by the National Natural Science Foundation of China （Grant Nos 10274017 and 10354001）, and the Natural Science Foundation of Hebei Province, China （Grant Nos 103097 and 603138）.
文摘Photoelectron is the foundation of latent image formation, the decay process of photoelectrons is influenced by all kinds of trapping centres in silver halide. By analysing the mechanism of latent image formation it is found that electron trap, hole trap, and one kind of recombination centre where free electron and trapped hole recombine are the main trapping centres in silver halide. Different trapping centres have different influences on the photoelectron behaviour. The effects of all kinds of typical trapping centres on the decay of photoelectrons are systematically investigated by solving the photoelectron decay kinetic equations. The results are in agreement with those obtained in the microwave absorption dielectric spectrum experiment.
