Land transport can no longer meet the requirements.European transport can be described by these words−crowded motorways and cities,dangerous emissions,ubiquitous traffic accidents,delays,expensive railways.Solutions a...Land transport can no longer meet the requirements.European transport can be described by these words−crowded motorways and cities,dangerous emissions,ubiquitous traffic accidents,delays,expensive railways.Solutions are being sought to transfer a large part of passengers and especially freight transport to(high-speed)rail,and efforts are moving towards electromobility,car-sharing,5G-connectivity,autonomous driving,MaaS(Mobility as a Service)-coordinated transport or hyperloop-type solutions.However,all these solutions have additional challenges and limitations.Solutions are not being searched where they really exist-in the mutual adaptation of road and rail vehicles and their deep cooperation.The ComplexTrans project shows that simply adapting the dimensions and functions of road and rail vehicles can eliminate(or at least significantly reduce)all the problems of existing land transport.The main features of the ComplexTrans system are sufficient parking spaces,reduction of urban and non-urban congestion,electric vehicles with unlimited range and cheaper than standard cars,cheaper and more accessible battery charging,“autonomous ride”,solving the overlap between passenger and freight rail transport and making it self-financing,transferring intercity freight transport to rail,replacing part of continental air transport and many others.The cost-effective and clustered individual transport and individualised public transport of the ComplexTrans system also bring very significant reductions in the risk of transmission of covid-19 and other contagious diseases during transport.展开更多
Achieving high-energy density remains a key objective for advanced energy storage systems.However,challenges,such as poor cathode conductivity,anode dendrite formation,polysulfide shuttling,and electrolyte degradation...Achieving high-energy density remains a key objective for advanced energy storage systems.However,challenges,such as poor cathode conductivity,anode dendrite formation,polysulfide shuttling,and electrolyte degradation,continue to limit performance and stability.Molecular and ionic dipole interactions have emerged as an effective strategy to address these issues by regulating ionic transport,modulating solvation structures,optimizing interfacial chemistry,and enhancing charge transfer kinetics.These interactions also stabilize electrode interfaces,suppress side reactions,and mitigate anode corrosion,collectively improving the durability of high-energy batteries.A deeper understanding of these mechanisms is essential to guide the design of next-generation battery materials.Herein,this review summarizes the development,classification,and advantages of dipole interactions in high-energy batteries.The roles of dipoles,including facilitating ion transport,controlling solvation dynamics,stabilizing the electric double layer,optimizing solid electrolyte interphase and cathode–electrolyte interface layers,and inhibiting parasitic reactions—are comprehensively discussed.Finally,perspectives on future research directions are proposed to advance dipole-enabled strategies for high-performance energy storage.This review aims to provide insights into the rational design of dipole-interactive systems and promote the progress of electrochemical energy storage technologies.展开更多
Background:Excessive use of inorganic trace minerals(ITMs)in swine production leads to high fecal mineral excretion and environmental risks,while most studies on organic trace minerals(OTMs)focus on single elements,wi...Background:Excessive use of inorganic trace minerals(ITMs)in swine production leads to high fecal mineral excretion and environmental risks,while most studies on organic trace minerals(OTMs)focus on single elements,with limited data on the synergistic effects and molecular mechanisms of combined OTMs(Fe,Cu,Mn,Zn)in growing-finishing pigs.Methods:This study aimed to investigate the effects of graded levels of micromineral proteinates(combined OTMs)on growth performance,mineral metabolism,and mRNA expression of mineral regulatory proteins.A total of 360 crossbred Duroc×Landrace×Large White pigs(initial body weight 47.1±4.8 kg)were randomly assigned to 6 dietary treatments:basal diet without microminerals(CON),basal diet with ITMs at commercially recommended levels(IT),and basal diets with 15%(OT 15%),25%(OT 25%),35%(OT 35%)commercially recommended levels(CRL)of combined micromineral proteinates.After a 70-day feeding trial,samples were analyzed using ICP-OES,ELISA,and RT-qPCR.Results:Results showed that reduced levels(15-35%CRL)of micromineral proteinates did not significantly affect average daily gain,average daily feed intake,or feed conversion ratio(gain-to-feed ratio)compared to IT(P>0.05),but significantly increased plasma Cu(1.73-1.83μg/mL)and Zn(1.72-1.97μg/mL)concentrations(P<0.05)and elevated activities of Cu/Zn-superoxide dismutase(32.9-35.9 U/L)and manganese superoxide dismutase(20.5-24.1 U/L)compared to CON(P<0.05),with no significant differences from IT(P>0.05).Fecal excretion of Fe,Cu,Mn,and Zn was significantly reduced by 35-50%in OT 15%-OT 35%groups compared to IT(P<0.05).OT 25%group exhibited the highest apparent absorptivity of Fe(38.5%),Cu(27.8%),and Zn(42.4%)(P<0.05),which was associated with significantly regulated mRNA expression of mineral regulatory proteins:upregulated DMT1,FPN1,ZIP4,and MT1A in the duodenum,and modulated HAMP,ATP7B,ZIP14,and ZnT1 in the liver(P<0.05).Conclusion:In conclusion,dietary supplementation with 25%CRL or less of combined micromineral proteinates can fully meet the nutritional needs of growing-finishing pigs,improve mineral absorptivity,and reduce fecal mineral excretion by regulating intestinal and hepatic mineral transport and homeostatic proteins,providing a sustainable alternative to high-dose ITMs.展开更多
A key pathological feature of Parkinson’s disease(PD)is that lysosomes are overwhelmed with cellular materials that need to be degraded and cleared.While the build-up of protein is characteristic of neurodegenerative...A key pathological feature of Parkinson’s disease(PD)is that lysosomes are overwhelmed with cellular materials that need to be degraded and cleared.While the build-up of protein is characteristic of neurodegenerative diseases such as PD and Alzheimer’s disease(AD)and is thought to reflect lysosome dysfunction,lipid accumulation may also contribute to and be indicative of severe lysosomal dysfunction.Much is known about the detrimental effects of glucosylceramide accumulation in PD lysosomes.展开更多
To ensure the safe transportation of radioactive materials,numerous countries have established specific standards.For the transfer of fissile materials,it is imperative that the material within the packaging remains i...To ensure the safe transportation of radioactive materials,numerous countries have established specific standards.For the transfer of fissile materials,it is imperative that the material within the packaging remains in a subcritical state during routine,normal,and accidental transport conditions.In the event of an accident,the rods within the storage tank may become rearranged,introducing uncertainty that must be accounted for to ensure that criticality analysis results are conservative.Historically,this uncertainty was addressed overly conservatively due to limited research on non-uniform arrangement scenarios,which proved unsuitable for criticality safety analysis of spent fuel packages.This paper introduced three distinct methods to non-uniformly rearrange fuel rods—Uniform Arrangement by Blocks,Layer-by-Layer Determination,and Birdcage Deformation—and meticulously evaluates the influences of rod rearrangement on the effective multiplication factor of neutrons,k eff,utilizing the Monte Carlo method.Ultimately,this study presents a holistic method capable of encompassing the entire spectrum of potential effects stemming from the rearrangement of fuel rods during rods mispositioning accident.By augmenting the safety margin,this approach proves to be adeptly suited for the criticality safety analysis of nuclear fuel transport containers.展开更多
In tomato,early fruit development involves rapid cell division and expansion,which are highly dependent on sugar availability(Huang et al.,2025;Yuan et al.,2025).After fruit set,soluble sugars are loaded into pericarp...In tomato,early fruit development involves rapid cell division and expansion,which are highly dependent on sugar availability(Huang et al.,2025;Yuan et al.,2025).After fruit set,soluble sugars are loaded into pericarp cells through the symplasmic(cytosol)or apoplasmic pathway(cell wall and extracellular matrix)(Patrick and Offler,1996).Sucrose,as the major form of carbon translocated to tomato fruit,can be directly unloaded into fruit cells.However,some sucrose can be hydrolyzed by extracellular invertase,producing glucose and fructose for metabolism and biosynthesis in pericarp cells(Ruan,2014).展开更多
Utilizing transporter-mediated drug delivery to achieve effective oral absorption emerges as a promising strategy.Researchers have been concentrated on discovering solutions to the issues of low solubility and poor pe...Utilizing transporter-mediated drug delivery to achieve effective oral absorption emerges as a promising strategy.Researchers have been concentrated on discovering solutions to the issues of low solubility and poor permeability of insoluble drugs,whereas,current reports have revealed that drug transporter proteins are abundantly expressed in the mucosa of intestinal epithelial cells,and that their mediated drug absorption effectively improved the bioavailability of orally administered drugs.There are two main categories based on the transporter mechanism,which include the family of ATP-binding cassette(ABC)transporters with efflux effects that reduce drug bioavailability and the family of solute carriers(SLC)transporters with uptake effects that promote drug absorption,respectively.Thus,we review studies of intestinal transporter-mediated delivery of drugs to enhance oral absorption,including the types of intestinal transporters,distribution characteristics,and strategies for enhancing oral absorption using transporter-mediated drug delivery systems are summarized,with the aim of providing important theoretical references for the development of intestinal-targeted delivery system.展开更多
Sulfate transporters(SULTRs)facilitate sulfate uptake and transport in plants.In plants,SULTRs can be classified into four distinct functional groups,among which SULTR3 members are the least characterized,and their fu...Sulfate transporters(SULTRs)facilitate sulfate uptake and transport in plants.In plants,SULTRs can be classified into four distinct functional groups,among which SULTR3 members are the least characterized,and their functions have not yet been confirmed,especially for SULTR3 in rice.In this study,we analyzed the expression patterns,subcellular localization,and inorganic phosphate(Pi)transporter activity of SULTR3 proteins in yeast.Except for OsSULTR3.4,which localized to the plasma membrane,other OsSULTR3 members were localized to the endoplasmic reticulum(ER)membrane in rice protoplast cells.展开更多
BACKGROUND Chronic enteropathy associated with solute carrier organic anion transporter family member 2A1(SLCO2A1)(CEAS)is a rare autosomal recessive hereditary disease characterized by anemia,hypoproteinemia,abdomina...BACKGROUND Chronic enteropathy associated with solute carrier organic anion transporter family member 2A1(SLCO2A1)(CEAS)is a rare autosomal recessive hereditary disease characterized by anemia,hypoproteinemia,abdominal pain,diarrhea,and multiple shallow ulcers in the small intestine.Genetic analysis for SLCO2A1 mutations has identified more than 10 variant types,including the mostly reported c.940+1G>A splice site mutation.CASE SUMMARY Herein,we described a 33-year-old female patient who was admitted for anemia,edema,and a positive fecal occult blood test,unaccompanied by abdominal pain and diarrhea.She was diagnosed with CEAS due to compound heterozygous variants,c.940+1G>cA(splice-5)and c.1658T>A(p.Ile553Asn)in SLCO2A1,which had not been previously reported.Importantly,we reviewed 132 reported CEAS patients,which showed that anemia(87.3%)and hypoproteinemia(81%)were the most common symptoms.Nearly 25.8%of patients only had a positive result of fecal occult blood,without any symptoms of gastrointestinal bleeding.CONCLUSION In conclusion,fecal tests should be repeated in patients with anemia and edema to find clues for chronic enteropathy,including the rare cause-CEAS.展开更多
Solid lipid nanoparticles(SLN)could enhance the oral bioavailability of loaded protein and peptide drugs through lymphatic transport.Natural oligopeptides regulate nearly all vital processes and serve as a nitrogen so...Solid lipid nanoparticles(SLN)could enhance the oral bioavailability of loaded protein and peptide drugs through lymphatic transport.Natural oligopeptides regulate nearly all vital processes and serve as a nitrogen source for nourishment.They are mainly transported by oligopeptide transporter-1(PepT-1)which are primarily expressed in the intestine with the characteristics of high-capacity and low energy consumption.Our preliminary research discovered the transmembrane transport of SLN could be improved by stimulating the oligopeptide absorption pathway.This implied the potential of combining the advantages of SLN with oligopeptide transporter mediated transportation.Herein,two kinds of dipeptide modified SLN were designed with insulin and glucagon like peptide-1(GLP-1)analogue exenatide as model drugs.These drugs loaded SLN showed enhanced oral bioavailability and hypoglycemic effect in both type I diabetic C57BL/6mice and type II diabetic KKAymice.Compared with un-modified SLN,dipeptide-modified SLN could be internalized by intestinal epithelial cells via PepT-1-mediated endocytosis with higher uptake.Interestingly,after internalization,more SLN could access the systemic circulation via lymphatic transport pathway,highlighting the potential to combine the oligopeptide-absorption route with SLN for oral drug delivery.展开更多
To investigate groundwater flow and solute transport characteristics of the karst trough zone in China,tracer experiments were conducted at two adjacent typical karst groundwater flow systems(Yuquandong(YQD)and Migong...To investigate groundwater flow and solute transport characteristics of the karst trough zone in China,tracer experiments were conducted at two adjacent typical karst groundwater flow systems(Yuquandong(YQD)and Migongquan(MGQ))in Sixi valley,western Hubei,China.Highresolution continuous monitoring was utilized to obtain breakthrough curves(BTCs),which were then analyzed using the multi-dispersion model(MDM)and the two-region nonequilibrium model(2RNE)with basic parameters calculated by CXTFIT and QTRACER2.Results showed that:(1)YQD flow system had a complex infiltration matrix with overland flow,conduit flow and fracture flow,while the MGQ flow system was dominated by conduit flow with fast flow transport velocity,but also small amount of fracture flow there;(2)They were well fitted based on the MDM(R^2=0.928)and 2RNE(R^2=0.947)models,indicating that they had strong adaptability in the karst trough zone;(3)conceptual models for YQD and MGQ groundwater systems were generalized.In YQD system,the solute was transported via overland flow during intense rainfall,while some infiltrated down into fissures and conduits.In MGQ system,most were directly transported to spring outlet in the fissureconduit network.展开更多
The conventional perception of astrocytes as mere supportive cells within the brain has recently been called into question by empirical evidence, which has revealed their active involvement in regulating brain functio...The conventional perception of astrocytes as mere supportive cells within the brain has recently been called into question by empirical evidence, which has revealed their active involvement in regulating brain function and encoding behaviors associated with emotions.Specifically, astrocytes in the basolateral amygdala have been found to play a role in the modulation of anxiety-like behaviors triggered by chronic stress. Nevertheless, the precise molecular mechanisms by which basolateral amygdala astrocytes regulate chronic stress–induced anxiety-like behaviors remain to be fully elucidated. In this study, we found that in a mouse model of anxiety triggered by unpredictable chronic mild stress, the expression of excitatory amino acid transporter 2 was upregulated in the basolateral amygdala. Interestingly, our findings indicate that the targeted knockdown of excitatory amino acid transporter 2 specifically within the basolateral amygdala astrocytes was able to rescue the anxiety-like behavior in mice subjected to stress. Furthermore, we found that the overexpression of excitatory amino acid transporter 2 in the basolateral amygdala, whether achieved through intracranial administration of excitatory amino acid transporter 2agonists or through injection of excitatory amino acid transporter 2-overexpressing viruses with GfaABC1D promoters, evoked anxiety-like behavior in mice. Our single-nucleus RNA sequencing analysis further confirmed that chronic stress induced an upregulation of excitatory amino acid transporter 2 specifically in astrocytes in the basolateral amygdala. Moreover, through in vivo calcium signal recordings, we found that the frequency of calcium activity in the basolateral amygdala of mice subjected to chronic stress was higher compared with normal mice.After knocking down the expression of excitatory amino acid transporter 2 in the basolateral amygdala, the frequency of calcium activity was not significantly increased, and anxiety-like behavior was obviously mitigated. Additionally, administration of an excitatory amino acid transporter 2 inhibitor in the basolateral amygdala yielded a notable reduction in anxiety level among mice subjected to stress. These results suggest that basolateral amygdala astrocytic excitatory amino acid transporter 2 plays a role in in the regulation of unpredictable chronic mild stress-induced anxiety-like behavior by impacting the activity of local glutamatergic neurons, and targeting excitatory amino acid transporter 2 in the basolateral amygdala holds therapeutic promise for addressing anxiety disorders.展开更多
The Janus fabrics designed for personal moisture/thermal regulation have garnered significant attention for their potential to enhance human comfort.However,the development of smart and dynamic fabrics capable of mana...The Janus fabrics designed for personal moisture/thermal regulation have garnered significant attention for their potential to enhance human comfort.However,the development of smart and dynamic fabrics capable of managing personal moisture/thermal comfort in response to changing external environments remains a challenge.Herein,a smart cellulose-based Janus fabric was designed to dynamically manage personal moisture/heat.The cotton fabric was grafted with N-isopropylacrylamide to construct a temperature-stimulated transport channel.Subsequently,hydrophobic ethyl cellulose and hydrophilic cellulose nanofiber were sprayed on the bottom and top sides of the fabric to obtain wettability gradient.The fabric exhibits anti-gravity directional liquid transportation from hydrophobic side to hydrophilic side,and can dynamically and continuously control the transportation time in a wide range of 3–66 s as the temperature increases from 10 to 40℃.This smart fabric can quickly dissipate heat at high temperatures,while at low temperatures,it can slow down the heat dissipation rate and prevent the human from becoming too cold.In addition,the fabric has UV shielding and photodynamic antibacterial properties through depositing graphitic carbon nitride nanosheets on the hydrophilic side.This smart fabric offers an innovative approach to maximizing personal comfort in environments with significant temperature variations.展开更多
Sucrose transporters(SUTs)contain multiple transmembrane domains that mediate sucrose transport and provide energy for plant growth and development.However,the role of OsSUTs in regulating rice quality and grain yield...Sucrose transporters(SUTs)contain multiple transmembrane domains that mediate sucrose transport and provide energy for plant growth and development.However,the role of OsSUTs in regulating rice quality and grain yield remains unclear.In this study,we identified five rice SUT genes(OsSUT1-OsSUT5)and examined their molecular characteristics and biological functions.OsSUT1,OsSUT2,and OsSUT4 were predominantly expressed in stems,while OsSUT3 and OsSUT5 showed higher expression in panicles.OsSUT1 and OsSUT4 are located on the plasma membrane,whereas OsSUT2,OsSUT3,and OsSUT5 are localized to the tonoplast.展开更多
Transportation systems are rapidly transforming in response to urbanization,sustainability challenges,and advances in digital technologies.This review synthesizes the intersection of artificial intelligence(AI),fuzzy ...Transportation systems are rapidly transforming in response to urbanization,sustainability challenges,and advances in digital technologies.This review synthesizes the intersection of artificial intelligence(AI),fuzzy logic,and multi-criteria decision-making(MCDM)in transportation research.A comprehensive literature search was conducted in the Scopus database,utilizing carefully selected AI,fuzzy,and MCDM keywords.Studies were rigorously screened according to explicit inclusion and exclusion criteria,resulting in 73 eligible publications spanning 2006-2025.The review protocol included transparent data extraction on methodological approaches,application domains,and geographic distribution.Key findings highlight the prevalence of hybrid fuzzyAHPand TOPSIS methods,the widespread integration of machine learning for prediction and optimization,and a predominant focus on logistics and infrastructure planning within the transportation sector.Geographic analysis underscores a marked concentration of research activity in Asia,while other regions remain underrepresented,signaling the need for broader international collaboration.The review also addresses persistent challenges such asmethodological complexity,data limitations,and model interpretability.Future research directions are proposed,including the integration of reinforcement learning,real-time analytics,and big data-driven adaptive solutions.This study offers a comprehensive synthesis and critical perspective,serving as a valuable reference for researchers,practitioners,and policymakers seeking to enhance the efficiency,resilience,and sustainability of transportation systems through intelligent decision-making frameworks.展开更多
Purpose–As an important part of the management of railway passenger transport,the rationality and effectiveness of the clearing method of railway passenger transport are directly related to the operating efficiency a...Purpose–As an important part of the management of railway passenger transport,the rationality and effectiveness of the clearing method of railway passenger transport are directly related to the operating efficiency and service quality of railway passenger transport enterprises.This paper aims to comprehensively and deeply discuss the evolution and development process of China’s railway passenger transport clearing method,analyze its characteristics and influences in each stage,identify the main factors affecting its evolution and development and then put forward thoughts on improving the future development of the clearing method.Design/methodology/approach–Through a detailed review of the railway passenger transport clearing methods from the planned economy period to the reform and opening up period and into the new century,the basis,mode,subject and object of clearing in different development stages are systematically compared.Findings–It comprehensively reveals the evolution of the clearing method,sorted out the characteristics and changes of the clearing method at each stage and the adaptability to the development of railway passenger transport at that time.The characteristics of the development of clearing measures for railway passenger transport in different stages and their far-reaching influence on railway passenger transport business are deeply analyzed.Originality/value–This paper summarized the factors influencing the development of China’s railway passenger transportation clearing approach evolution,including the simplified rules of clearing,enhanced the market adaptability,establishing and perfecting the incentive mechanism,strengthening the construction of informatization,etc.This paper puts forward the ways to improve the railway passenger transportation clearing future development thinking.展开更多
We investigate electron mesoscopic transport in a three-terminal setup with coupled quantum dots and a magnetic flux.By mapping the original transport problem into a non-Hermitian Hamiltonian form,we study the interpl...We investigate electron mesoscopic transport in a three-terminal setup with coupled quantum dots and a magnetic flux.By mapping the original transport problem into a non-Hermitian Hamiltonian form,we study the interplay between the coherent couplings between quantum dots,the magnetic flux,and the dissipation due to the tunnel coupling with the reservoirs.展开更多
The early responsive to dehydration-like(ERDL or ERD)subfamily,subclade within the monosaccharide transporter(MST)superfamily,is crucial in the regulation of growth and seed yield in Arabidopsis.Here,we identified Os ...The early responsive to dehydration-like(ERDL or ERD)subfamily,subclade within the monosaccharide transporter(MST)superfamily,is crucial in the regulation of growth and seed yield in Arabidopsis.Here,we identified Os ERD5 as an At ERDL6 homologue and explored the function of Os ERD5.We found that Os ERD5 overexpression significantly enhanced the tiller number and grain yield of rice.Os ERD5 was widely expressed in aboveground tissues,encoded a tonoplast-localized protein,and exhibited transport activities for fructose,glucose and mannose when expressed in yeast.Expression character assay revealed that Os ERD5 mediated hexose efflux across tonoplasts and participated in maintaining the diurnal rhythm-regulated intracellular hexose homeostasis.Additional physiological and molecular evidence showed that Os ERD5 overexpression promoted vacuolar glucose efflux,enhanced sucrose synthesis and transport,increased sugar content in the shoot base,and promoted rice tillering by activating the synthesis of cytokinin simultaneously repressing strigolactone and gibberellin signaling.This study elucidates the function of Os ERD5 and the mechanism underlying the overexpression of Os ERD5 increasing rice tillering and yield.展开更多
Purpose–This paper aims to provide a comprehensive analysis of the strategic adjustments in China’s transportation structure,with a particular focus on the pivotal role of railway freight and its integration into th...Purpose–This paper aims to provide a comprehensive analysis of the strategic adjustments in China’s transportation structure,with a particular focus on the pivotal role of railway freight and its integration into the modern logistics system.It seeks to address the need for a more nuanced understanding of the“road to rail”policy,emphasizing the importance of intermodal collaboration and service of fragmented market demands.Design/methodology/approach–The study employs a transport economics perspective to evaluate the achievements and shortcomings of China’s transportation structure optimization.It bases its assessment of the current state of railway freight logistics,multi-modal transportation and the broader implications for the transportation service market on data analysis.The methodology includes a review of existing policies,an examination of industry practices and a comparative analysis with global trends in railway logistics.Findings–The research underscores the importance of focusing on the development of non-bulk materials,noting the insufficiency in the development of China’s rail multi-modal transportation and highlighting the instructive value of successful cases in open-top container road-rail intermodal transportation.The study posits that the railway sector must enhance cooperation with other market entities,aligning with the lead enterprises in the logistics chain that are characterized by speed,high value and strong coordination capabilities,in order to better serve the transportation market.This approach moves away from a reliance on the railway’s own capabilities alone.Originality/value–This paper offers original insights into the transformation of railway freight in China,contributing to the body of knowledge on transportation economics and logistics.It provides valuable recommendations for policymakers and industry practitioners,emphasizing the strategic importance of railway logistics in the context of China’s economic development and intense competition in the supply chain.The value of the article lies in its comprehensive understanding of the complexities involved in the adjustment of transportation structures,providing direction for the market-oriented reform of China’s railway freight sector.展开更多
The commercialization of proton exchange membrane water electrolysis(PEMWE)for green hydrogen production hinges on the development of low-cost,high-performance titanium porous transport layers(PTLs).This study introdu...The commercialization of proton exchange membrane water electrolysis(PEMWE)for green hydrogen production hinges on the development of low-cost,high-performance titanium porous transport layers(PTLs).This study introduces a triple-layer Ti-PTL with a graded porous structure and a 75%ultra-high porosity backing layer,fabricated through tape casting and roll calendering.This triple-layer PTL,composed of a microporous layer,an interlayer,and a highly porous backing layer,enhances catalyst utilization,mechanical integrity,and mass transport.Digital twin technology using X-ray revealed increased contact area and triple-phase boundary at the interface with the catalyst layer,significantly improving oxygen evolution reaction kinetics.Numerical simulations demonstrated that the strategically designed porous structure of the triple-layer PTL facilitates efficient oxygen transport,mitigates oxygen accumulation,and improves reactant accessibility.Electrochemical evaluations showed improved performance,achieving 127 mV reduction in voltage at 2 A cm^(-2)compared to a commercial PTL,highlighting its potential to enhance PEMWE efficiency and cost-effectiveness.展开更多
基金This research is partly supported by project SGS-2019-001The 3-D visualisations were prepared by students of University of West Bohemia or by professional designers.
文摘Land transport can no longer meet the requirements.European transport can be described by these words−crowded motorways and cities,dangerous emissions,ubiquitous traffic accidents,delays,expensive railways.Solutions are being sought to transfer a large part of passengers and especially freight transport to(high-speed)rail,and efforts are moving towards electromobility,car-sharing,5G-connectivity,autonomous driving,MaaS(Mobility as a Service)-coordinated transport or hyperloop-type solutions.However,all these solutions have additional challenges and limitations.Solutions are not being searched where they really exist-in the mutual adaptation of road and rail vehicles and their deep cooperation.The ComplexTrans project shows that simply adapting the dimensions and functions of road and rail vehicles can eliminate(or at least significantly reduce)all the problems of existing land transport.The main features of the ComplexTrans system are sufficient parking spaces,reduction of urban and non-urban congestion,electric vehicles with unlimited range and cheaper than standard cars,cheaper and more accessible battery charging,“autonomous ride”,solving the overlap between passenger and freight rail transport and making it self-financing,transferring intercity freight transport to rail,replacing part of continental air transport and many others.The cost-effective and clustered individual transport and individualised public transport of the ComplexTrans system also bring very significant reductions in the risk of transmission of covid-19 and other contagious diseases during transport.
基金supported by the introduction of Talent Research Fund in Nanjing Institute of Technology(YKJ202204)the National Natural Science Foundation of China(52401282 and 52300206)the Natural Science Foundation of Jiangsu Province(BK20230701 and BK20230705).
文摘Achieving high-energy density remains a key objective for advanced energy storage systems.However,challenges,such as poor cathode conductivity,anode dendrite formation,polysulfide shuttling,and electrolyte degradation,continue to limit performance and stability.Molecular and ionic dipole interactions have emerged as an effective strategy to address these issues by regulating ionic transport,modulating solvation structures,optimizing interfacial chemistry,and enhancing charge transfer kinetics.These interactions also stabilize electrode interfaces,suppress side reactions,and mitigate anode corrosion,collectively improving the durability of high-energy batteries.A deeper understanding of these mechanisms is essential to guide the design of next-generation battery materials.Herein,this review summarizes the development,classification,and advantages of dipole interactions in high-energy batteries.The roles of dipoles,including facilitating ion transport,controlling solvation dynamics,stabilizing the electric double layer,optimizing solid electrolyte interphase and cathode–electrolyte interface layers,and inhibiting parasitic reactions—are comprehensively discussed.Finally,perspectives on future research directions are proposed to advance dipole-enabled strategies for high-performance energy storage.This review aims to provide insights into the rational design of dipole-interactive systems and promote the progress of electrochemical energy storage technologies.
基金financially supported by the Hainan Province Science and Technology Special Fund(Grant no:ZDYF2024XDNY187).
文摘Background:Excessive use of inorganic trace minerals(ITMs)in swine production leads to high fecal mineral excretion and environmental risks,while most studies on organic trace minerals(OTMs)focus on single elements,with limited data on the synergistic effects and molecular mechanisms of combined OTMs(Fe,Cu,Mn,Zn)in growing-finishing pigs.Methods:This study aimed to investigate the effects of graded levels of micromineral proteinates(combined OTMs)on growth performance,mineral metabolism,and mRNA expression of mineral regulatory proteins.A total of 360 crossbred Duroc×Landrace×Large White pigs(initial body weight 47.1±4.8 kg)were randomly assigned to 6 dietary treatments:basal diet without microminerals(CON),basal diet with ITMs at commercially recommended levels(IT),and basal diets with 15%(OT 15%),25%(OT 25%),35%(OT 35%)commercially recommended levels(CRL)of combined micromineral proteinates.After a 70-day feeding trial,samples were analyzed using ICP-OES,ELISA,and RT-qPCR.Results:Results showed that reduced levels(15-35%CRL)of micromineral proteinates did not significantly affect average daily gain,average daily feed intake,or feed conversion ratio(gain-to-feed ratio)compared to IT(P>0.05),but significantly increased plasma Cu(1.73-1.83μg/mL)and Zn(1.72-1.97μg/mL)concentrations(P<0.05)and elevated activities of Cu/Zn-superoxide dismutase(32.9-35.9 U/L)and manganese superoxide dismutase(20.5-24.1 U/L)compared to CON(P<0.05),with no significant differences from IT(P>0.05).Fecal excretion of Fe,Cu,Mn,and Zn was significantly reduced by 35-50%in OT 15%-OT 35%groups compared to IT(P<0.05).OT 25%group exhibited the highest apparent absorptivity of Fe(38.5%),Cu(27.8%),and Zn(42.4%)(P<0.05),which was associated with significantly regulated mRNA expression of mineral regulatory proteins:upregulated DMT1,FPN1,ZIP4,and MT1A in the duodenum,and modulated HAMP,ATP7B,ZIP14,and ZnT1 in the liver(P<0.05).Conclusion:In conclusion,dietary supplementation with 25%CRL or less of combined micromineral proteinates can fully meet the nutritional needs of growing-finishing pigs,improve mineral absorptivity,and reduce fecal mineral excretion by regulating intestinal and hepatic mineral transport and homeostatic proteins,providing a sustainable alternative to high-dose ITMs.
文摘A key pathological feature of Parkinson’s disease(PD)is that lysosomes are overwhelmed with cellular materials that need to be degraded and cleared.While the build-up of protein is characteristic of neurodegenerative diseases such as PD and Alzheimer’s disease(AD)and is thought to reflect lysosome dysfunction,lipid accumulation may also contribute to and be indicative of severe lysosomal dysfunction.Much is known about the detrimental effects of glucosylceramide accumulation in PD lysosomes.
文摘To ensure the safe transportation of radioactive materials,numerous countries have established specific standards.For the transfer of fissile materials,it is imperative that the material within the packaging remains in a subcritical state during routine,normal,and accidental transport conditions.In the event of an accident,the rods within the storage tank may become rearranged,introducing uncertainty that must be accounted for to ensure that criticality analysis results are conservative.Historically,this uncertainty was addressed overly conservatively due to limited research on non-uniform arrangement scenarios,which proved unsuitable for criticality safety analysis of spent fuel packages.This paper introduced three distinct methods to non-uniformly rearrange fuel rods—Uniform Arrangement by Blocks,Layer-by-Layer Determination,and Birdcage Deformation—and meticulously evaluates the influences of rod rearrangement on the effective multiplication factor of neutrons,k eff,utilizing the Monte Carlo method.Ultimately,this study presents a holistic method capable of encompassing the entire spectrum of potential effects stemming from the rearrangement of fuel rods during rods mispositioning accident.By augmenting the safety margin,this approach proves to be adeptly suited for the criticality safety analysis of nuclear fuel transport containers.
基金supported by The National Natural Science Foundation of China(Grant Nos.32120103010,32341045,and 32272729).
文摘In tomato,early fruit development involves rapid cell division and expansion,which are highly dependent on sugar availability(Huang et al.,2025;Yuan et al.,2025).After fruit set,soluble sugars are loaded into pericarp cells through the symplasmic(cytosol)or apoplasmic pathway(cell wall and extracellular matrix)(Patrick and Offler,1996).Sucrose,as the major form of carbon translocated to tomato fruit,can be directly unloaded into fruit cells.However,some sucrose can be hydrolyzed by extracellular invertase,producing glucose and fructose for metabolism and biosynthesis in pericarp cells(Ruan,2014).
基金funded by the National Natural Science Foundation of China(No.82304730)the Project of Academic and Technical Leaders in Major Disciplines in Jiangxi Province(No.20212BCJL23060)+3 种基金the Natural Science Foundation of Jiangxi Province(No.20232BAB216128)the Project of Jiangxi Provincial Department of Education(No.GJJ2200977)the Jiangxi University of Chinese Medicine Science and Technology Innovation Team Development Program(Nos.CXTD-22004,CXTD-22008)the PhD Startup Foundation of Affiliated Hospital of Jiangxi University of Chinese Medicine(No.23KYQDZJ02).
文摘Utilizing transporter-mediated drug delivery to achieve effective oral absorption emerges as a promising strategy.Researchers have been concentrated on discovering solutions to the issues of low solubility and poor permeability of insoluble drugs,whereas,current reports have revealed that drug transporter proteins are abundantly expressed in the mucosa of intestinal epithelial cells,and that their mediated drug absorption effectively improved the bioavailability of orally administered drugs.There are two main categories based on the transporter mechanism,which include the family of ATP-binding cassette(ABC)transporters with efflux effects that reduce drug bioavailability and the family of solute carriers(SLC)transporters with uptake effects that promote drug absorption,respectively.Thus,we review studies of intestinal transporter-mediated delivery of drugs to enhance oral absorption,including the types of intestinal transporters,distribution characteristics,and strategies for enhancing oral absorption using transporter-mediated drug delivery systems are summarized,with the aim of providing important theoretical references for the development of intestinal-targeted delivery system.
基金supported by the National Natural Science Foundation of China(Grant Nos.32130096 and 32172667)the Central Public-Interest Scientific Institution Basal Research Fund,China(Grant No.Y2022QC14).
文摘Sulfate transporters(SULTRs)facilitate sulfate uptake and transport in plants.In plants,SULTRs can be classified into four distinct functional groups,among which SULTR3 members are the least characterized,and their functions have not yet been confirmed,especially for SULTR3 in rice.In this study,we analyzed the expression patterns,subcellular localization,and inorganic phosphate(Pi)transporter activity of SULTR3 proteins in yeast.Except for OsSULTR3.4,which localized to the plasma membrane,other OsSULTR3 members were localized to the endoplasmic reticulum(ER)membrane in rice protoplast cells.
基金Supported by the National Natural Science Foundation of China(General Program),No.82000493Peking University People’s Hospital Scientific Research Development Funds,No.RDJP2023-09.
文摘BACKGROUND Chronic enteropathy associated with solute carrier organic anion transporter family member 2A1(SLCO2A1)(CEAS)is a rare autosomal recessive hereditary disease characterized by anemia,hypoproteinemia,abdominal pain,diarrhea,and multiple shallow ulcers in the small intestine.Genetic analysis for SLCO2A1 mutations has identified more than 10 variant types,including the mostly reported c.940+1G>A splice site mutation.CASE SUMMARY Herein,we described a 33-year-old female patient who was admitted for anemia,edema,and a positive fecal occult blood test,unaccompanied by abdominal pain and diarrhea.She was diagnosed with CEAS due to compound heterozygous variants,c.940+1G>cA(splice-5)and c.1658T>A(p.Ile553Asn)in SLCO2A1,which had not been previously reported.Importantly,we reviewed 132 reported CEAS patients,which showed that anemia(87.3%)and hypoproteinemia(81%)were the most common symptoms.Nearly 25.8%of patients only had a positive result of fecal occult blood,without any symptoms of gastrointestinal bleeding.CONCLUSION In conclusion,fecal tests should be repeated in patients with anemia and edema to find clues for chronic enteropathy,including the rare cause-CEAS.
基金supported by National Key Research and Development Program of China(Grant No.2021YFE0115200)the Regional Innovation and Development Joint Fund of National Natural Science Foundation of China(Grant No.U22A20356).
文摘Solid lipid nanoparticles(SLN)could enhance the oral bioavailability of loaded protein and peptide drugs through lymphatic transport.Natural oligopeptides regulate nearly all vital processes and serve as a nitrogen source for nourishment.They are mainly transported by oligopeptide transporter-1(PepT-1)which are primarily expressed in the intestine with the characteristics of high-capacity and low energy consumption.Our preliminary research discovered the transmembrane transport of SLN could be improved by stimulating the oligopeptide absorption pathway.This implied the potential of combining the advantages of SLN with oligopeptide transporter mediated transportation.Herein,two kinds of dipeptide modified SLN were designed with insulin and glucagon like peptide-1(GLP-1)analogue exenatide as model drugs.These drugs loaded SLN showed enhanced oral bioavailability and hypoglycemic effect in both type I diabetic C57BL/6mice and type II diabetic KKAymice.Compared with un-modified SLN,dipeptide-modified SLN could be internalized by intestinal epithelial cells via PepT-1-mediated endocytosis with higher uptake.Interestingly,after internalization,more SLN could access the systemic circulation via lymphatic transport pathway,highlighting the potential to combine the oligopeptide-absorption route with SLN for oral drug delivery.
基金supported by the National Natural Science Foundation of China(Nos.42007178 and 41907327)the Natural Science Foundation of Hubei(Nos.2020CFB463 and 2019CFB372)+4 种基金China Geological Survey(Nos.DD20160304 and DD20190824)Fundamental Research Funds for the Central Universities(Nos.CUG 190644 and CUGL180817)National Key Research and Development Program(No.2019YFC1805502)Key Laboratory of Karst Dynamics,MNR and GZAR(Institute of Karst Geology,CAGS)Guilin(No.KDL201703)Key Laboratory of Karst Ecosystem and Treatment of Rocky Desertification,MNR and IRCK by UNESCO(No.KDL201903)。
文摘To investigate groundwater flow and solute transport characteristics of the karst trough zone in China,tracer experiments were conducted at two adjacent typical karst groundwater flow systems(Yuquandong(YQD)and Migongquan(MGQ))in Sixi valley,western Hubei,China.Highresolution continuous monitoring was utilized to obtain breakthrough curves(BTCs),which were then analyzed using the multi-dispersion model(MDM)and the two-region nonequilibrium model(2RNE)with basic parameters calculated by CXTFIT and QTRACER2.Results showed that:(1)YQD flow system had a complex infiltration matrix with overland flow,conduit flow and fracture flow,while the MGQ flow system was dominated by conduit flow with fast flow transport velocity,but also small amount of fracture flow there;(2)They were well fitted based on the MDM(R^2=0.928)and 2RNE(R^2=0.947)models,indicating that they had strong adaptability in the karst trough zone;(3)conceptual models for YQD and MGQ groundwater systems were generalized.In YQD system,the solute was transported via overland flow during intense rainfall,while some infiltrated down into fissures and conduits.In MGQ system,most were directly transported to spring outlet in the fissureconduit network.
基金supported by the National Natural Science Foundation of China,Nos.32371070 (to JT),31761163005 (to JT),32100824 (to QX)the Shenzhen Science and Technology Program,Nos.RCBS20210609104606024 (to QX),JCY20210324101813035 (to DL)+4 种基金the Guangdong Provincial Key S&T Program,No.2018B030336001 (to JT)the Key Basic Research Program of Shenzhen Science and Technology Innovation Commission,Nos.JCYJ20200109115405930 (to JT),JCYJ20220818101615033 (to DL),JCYJ20210324115811031 (to QX),JCYJ20200109150717745 (to QX)Shenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases,No.ZDSYS20220304163558001 (to JT)Guangdong Provincial Key Laboratory of Brain Connectome and Behavior,No.2023B1212060055 (to JT)the China Postdoctoral Science Foundation,No.2021M693298 (to QX)。
文摘The conventional perception of astrocytes as mere supportive cells within the brain has recently been called into question by empirical evidence, which has revealed their active involvement in regulating brain function and encoding behaviors associated with emotions.Specifically, astrocytes in the basolateral amygdala have been found to play a role in the modulation of anxiety-like behaviors triggered by chronic stress. Nevertheless, the precise molecular mechanisms by which basolateral amygdala astrocytes regulate chronic stress–induced anxiety-like behaviors remain to be fully elucidated. In this study, we found that in a mouse model of anxiety triggered by unpredictable chronic mild stress, the expression of excitatory amino acid transporter 2 was upregulated in the basolateral amygdala. Interestingly, our findings indicate that the targeted knockdown of excitatory amino acid transporter 2 specifically within the basolateral amygdala astrocytes was able to rescue the anxiety-like behavior in mice subjected to stress. Furthermore, we found that the overexpression of excitatory amino acid transporter 2 in the basolateral amygdala, whether achieved through intracranial administration of excitatory amino acid transporter 2agonists or through injection of excitatory amino acid transporter 2-overexpressing viruses with GfaABC1D promoters, evoked anxiety-like behavior in mice. Our single-nucleus RNA sequencing analysis further confirmed that chronic stress induced an upregulation of excitatory amino acid transporter 2 specifically in astrocytes in the basolateral amygdala. Moreover, through in vivo calcium signal recordings, we found that the frequency of calcium activity in the basolateral amygdala of mice subjected to chronic stress was higher compared with normal mice.After knocking down the expression of excitatory amino acid transporter 2 in the basolateral amygdala, the frequency of calcium activity was not significantly increased, and anxiety-like behavior was obviously mitigated. Additionally, administration of an excitatory amino acid transporter 2 inhibitor in the basolateral amygdala yielded a notable reduction in anxiety level among mice subjected to stress. These results suggest that basolateral amygdala astrocytic excitatory amino acid transporter 2 plays a role in in the regulation of unpredictable chronic mild stress-induced anxiety-like behavior by impacting the activity of local glutamatergic neurons, and targeting excitatory amino acid transporter 2 in the basolateral amygdala holds therapeutic promise for addressing anxiety disorders.
基金support of this work by National Key Research and Development Program of China(2019YFC19059003)the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(23KJB430024)+1 种基金Jiangsu Funding Program for Excellent Postdoctoral Talent(2023ZB680)Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)are gratefully acknowledged.
文摘The Janus fabrics designed for personal moisture/thermal regulation have garnered significant attention for their potential to enhance human comfort.However,the development of smart and dynamic fabrics capable of managing personal moisture/thermal comfort in response to changing external environments remains a challenge.Herein,a smart cellulose-based Janus fabric was designed to dynamically manage personal moisture/heat.The cotton fabric was grafted with N-isopropylacrylamide to construct a temperature-stimulated transport channel.Subsequently,hydrophobic ethyl cellulose and hydrophilic cellulose nanofiber were sprayed on the bottom and top sides of the fabric to obtain wettability gradient.The fabric exhibits anti-gravity directional liquid transportation from hydrophobic side to hydrophilic side,and can dynamically and continuously control the transportation time in a wide range of 3–66 s as the temperature increases from 10 to 40℃.This smart fabric can quickly dissipate heat at high temperatures,while at low temperatures,it can slow down the heat dissipation rate and prevent the human from becoming too cold.In addition,the fabric has UV shielding and photodynamic antibacterial properties through depositing graphitic carbon nitride nanosheets on the hydrophilic side.This smart fabric offers an innovative approach to maximizing personal comfort in environments with significant temperature variations.
基金supported by the National Key Research and Development Program of China(Grant No.2023YFF1000500)the National Natural Science Foundation of China(Grant Nos.32372099,32172080,and 32188102)the Innovation Program of the Chinese Academy of Agricultural Sciences,China(Grant No.CAAS-CSCB-202402).
文摘Sucrose transporters(SUTs)contain multiple transmembrane domains that mediate sucrose transport and provide energy for plant growth and development.However,the role of OsSUTs in regulating rice quality and grain yield remains unclear.In this study,we identified five rice SUT genes(OsSUT1-OsSUT5)and examined their molecular characteristics and biological functions.OsSUT1,OsSUT2,and OsSUT4 were predominantly expressed in stems,while OsSUT3 and OsSUT5 showed higher expression in panicles.OsSUT1 and OsSUT4 are located on the plasma membrane,whereas OsSUT2,OsSUT3,and OsSUT5 are localized to the tonoplast.
文摘Transportation systems are rapidly transforming in response to urbanization,sustainability challenges,and advances in digital technologies.This review synthesizes the intersection of artificial intelligence(AI),fuzzy logic,and multi-criteria decision-making(MCDM)in transportation research.A comprehensive literature search was conducted in the Scopus database,utilizing carefully selected AI,fuzzy,and MCDM keywords.Studies were rigorously screened according to explicit inclusion and exclusion criteria,resulting in 73 eligible publications spanning 2006-2025.The review protocol included transparent data extraction on methodological approaches,application domains,and geographic distribution.Key findings highlight the prevalence of hybrid fuzzyAHPand TOPSIS methods,the widespread integration of machine learning for prediction and optimization,and a predominant focus on logistics and infrastructure planning within the transportation sector.Geographic analysis underscores a marked concentration of research activity in Asia,while other regions remain underrepresented,signaling the need for broader international collaboration.The review also addresses persistent challenges such asmethodological complexity,data limitations,and model interpretability.Future research directions are proposed,including the integration of reinforcement learning,real-time analytics,and big data-driven adaptive solutions.This study offers a comprehensive synthesis and critical perspective,serving as a valuable reference for researchers,practitioners,and policymakers seeking to enhance the efficiency,resilience,and sustainability of transportation systems through intelligent decision-making frameworks.
基金supported by the Research and Development Plan Project of China State Railway Group Co.,Ltd.(Project No.P2023X029).
文摘Purpose–As an important part of the management of railway passenger transport,the rationality and effectiveness of the clearing method of railway passenger transport are directly related to the operating efficiency and service quality of railway passenger transport enterprises.This paper aims to comprehensively and deeply discuss the evolution and development process of China’s railway passenger transport clearing method,analyze its characteristics and influences in each stage,identify the main factors affecting its evolution and development and then put forward thoughts on improving the future development of the clearing method.Design/methodology/approach–Through a detailed review of the railway passenger transport clearing methods from the planned economy period to the reform and opening up period and into the new century,the basis,mode,subject and object of clearing in different development stages are systematically compared.Findings–It comprehensively reveals the evolution of the clearing method,sorted out the characteristics and changes of the clearing method at each stage and the adaptability to the development of railway passenger transport at that time.The characteristics of the development of clearing measures for railway passenger transport in different stages and their far-reaching influence on railway passenger transport business are deeply analyzed.Originality/value–This paper summarized the factors influencing the development of China’s railway passenger transportation clearing approach evolution,including the simplified rules of clearing,enhanced the market adaptability,establishing and perfecting the incentive mechanism,strengthening the construction of informatization,etc.This paper puts forward the ways to improve the railway passenger transportation clearing future development thinking.
基金supported by the National Key R&D Program of China(Grant No.2022YFA1404400)the National Natural Science Foundation of China(Grant No.12125504 and 12305050)+2 种基金Zhejiang Provincial Natural Science Foundation of China(Grant No.LZ25A050001)the Hundred Talents Program of the Chinese Academy of Sciencesthe Natural Science Foundation of Jiangsu Higher Education Institutions of China(Grant No.23KJB140017)。
文摘We investigate electron mesoscopic transport in a three-terminal setup with coupled quantum dots and a magnetic flux.By mapping the original transport problem into a non-Hermitian Hamiltonian form,we study the interplay between the coherent couplings between quantum dots,the magnetic flux,and the dissipation due to the tunnel coupling with the reservoirs.
基金supported by the National Natural Science Foundation of China(32401743)the Earmarked Fund for the China Agriculture Research System(CARS-01)+1 种基金the Hunan Natural Science Foundation Project(2021JJ40235)the Science and Technology Innovation Program of Hunan Province(2022RC3053)。
文摘The early responsive to dehydration-like(ERDL or ERD)subfamily,subclade within the monosaccharide transporter(MST)superfamily,is crucial in the regulation of growth and seed yield in Arabidopsis.Here,we identified Os ERD5 as an At ERDL6 homologue and explored the function of Os ERD5.We found that Os ERD5 overexpression significantly enhanced the tiller number and grain yield of rice.Os ERD5 was widely expressed in aboveground tissues,encoded a tonoplast-localized protein,and exhibited transport activities for fructose,glucose and mannose when expressed in yeast.Expression character assay revealed that Os ERD5 mediated hexose efflux across tonoplasts and participated in maintaining the diurnal rhythm-regulated intracellular hexose homeostasis.Additional physiological and molecular evidence showed that Os ERD5 overexpression promoted vacuolar glucose efflux,enhanced sucrose synthesis and transport,increased sugar content in the shoot base,and promoted rice tillering by activating the synthesis of cytokinin simultaneously repressing strigolactone and gibberellin signaling.This study elucidates the function of Os ERD5 and the mechanism underlying the overexpression of Os ERD5 increasing rice tillering and yield.
基金supported by the Yuxiu Innovation Project of NCUT(Grant No.2024NCUTYXCX211).
文摘Purpose–This paper aims to provide a comprehensive analysis of the strategic adjustments in China’s transportation structure,with a particular focus on the pivotal role of railway freight and its integration into the modern logistics system.It seeks to address the need for a more nuanced understanding of the“road to rail”policy,emphasizing the importance of intermodal collaboration and service of fragmented market demands.Design/methodology/approach–The study employs a transport economics perspective to evaluate the achievements and shortcomings of China’s transportation structure optimization.It bases its assessment of the current state of railway freight logistics,multi-modal transportation and the broader implications for the transportation service market on data analysis.The methodology includes a review of existing policies,an examination of industry practices and a comparative analysis with global trends in railway logistics.Findings–The research underscores the importance of focusing on the development of non-bulk materials,noting the insufficiency in the development of China’s rail multi-modal transportation and highlighting the instructive value of successful cases in open-top container road-rail intermodal transportation.The study posits that the railway sector must enhance cooperation with other market entities,aligning with the lead enterprises in the logistics chain that are characterized by speed,high value and strong coordination capabilities,in order to better serve the transportation market.This approach moves away from a reliance on the railway’s own capabilities alone.Originality/value–This paper offers original insights into the transformation of railway freight in China,contributing to the body of knowledge on transportation economics and logistics.It provides valuable recommendations for policymakers and industry practitioners,emphasizing the strategic importance of railway logistics in the context of China’s economic development and intense competition in the supply chain.The value of the article lies in its comprehensive understanding of the complexities involved in the adjustment of transportation structures,providing direction for the market-oriented reform of China’s railway freight sector.
基金supported by the collaborative research project of Hyundai Motor Company.Also,this work was supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(No.RS-2024-00406086,RS-2024-00338569,and RS-2024-00467191)。
文摘The commercialization of proton exchange membrane water electrolysis(PEMWE)for green hydrogen production hinges on the development of low-cost,high-performance titanium porous transport layers(PTLs).This study introduces a triple-layer Ti-PTL with a graded porous structure and a 75%ultra-high porosity backing layer,fabricated through tape casting and roll calendering.This triple-layer PTL,composed of a microporous layer,an interlayer,and a highly porous backing layer,enhances catalyst utilization,mechanical integrity,and mass transport.Digital twin technology using X-ray revealed increased contact area and triple-phase boundary at the interface with the catalyst layer,significantly improving oxygen evolution reaction kinetics.Numerical simulations demonstrated that the strategically designed porous structure of the triple-layer PTL facilitates efficient oxygen transport,mitigates oxygen accumulation,and improves reactant accessibility.Electrochemical evaluations showed improved performance,achieving 127 mV reduction in voltage at 2 A cm^(-2)compared to a commercial PTL,highlighting its potential to enhance PEMWE efficiency and cost-effectiveness.
