BACKGROUND At present,the influencing factors of social function in patients with residual depressive symptoms are still unclear.Residual depressive symptoms are highly harmful,leading to low mood in patients,affectin...BACKGROUND At present,the influencing factors of social function in patients with residual depressive symptoms are still unclear.Residual depressive symptoms are highly harmful,leading to low mood in patients,affecting work and interpersonal communication,increasing the risk of recurrence,and adding to the burden on families.Studying the influencing factors of their social function is of great significance.AIM To explore the social function score and its influencing factors in patients with residual depressive symptoms.METHODS This observational study surveyed patients with residual depressive symptoms(case group)and healthy patients undergoing physical examinations(control group).Participants were admitted between January 2022 and December 2023.Social functioning was assessed using the Sheehan Disability Scale(SDS),and scores were compared between groups.Factors influencing SDS scores in patients with residual depressive symptoms were analyzed by applying multiple linear regression while using the receiver operating characteristic curve,and these RESULTS The SDS scores of the 158 patients with depressive symptoms were 11.48±3.26.Compared with the control group,the SDS scores and all items in the case group were higher.SDS scores were higher in patients with relapse,discon-tinuous medication,drug therapy alone,severe somatic symptoms,obvious residual symptoms,and anxiety scores≥8.Disease history,medication compliance,therapy method,and residual symptoms correlated positively with SDS scores(r=0.354,0.414,0.602,and 0.456,respectively).Independent influencing factors included disease history,medication compliance,therapy method,somatic symptoms,residual symptoms,and anxiety scores(P<0.05).The areas under the curve for predicting social functional impairment using these factors were 0.713,0.559,0.684,0.729,0.668,and 0.628,respectively,with sensitivities of 79.2%,61.8%,76.8%,81.7%,63.6%,and 65.5%and specificities of 83.3%,87.5%,82.6%,83.3%,86.7%,and 92.1%,respectively.CONCLUSION The social function scores of patients with residual symptoms of depression are high.They are affected by disease history,medication compliance,therapy method,degree of somatic symptoms,residual symptoms,and anxiety.展开更多
BACKGROUND Adolescents with an evening chronotype are at higher risk for mental health problems,such as depression and anxiety.However,the mechanisms underlying this relationship are not well understood.Sleep disturba...BACKGROUND Adolescents with an evening chronotype are at higher risk for mental health problems,such as depression and anxiety.However,the mechanisms underlying this relationship are not well understood.Sleep disturbances and impaired social functioning may mediate this association.AIM To examine the mediating roles of sleep quality and social functioning in the relationship between chronotype and mental health in adolescents.METHODS A cross-sectional survey was conducted among 381 adolescents(mean age 14.3 years;61.9%male)using the Morningness-Eveningness Questionnaire,Hamilton Depression Rating Scale,Hamilton Anxiety Scale,Pittsburgh Sleep Quality Index,and Social Disability Screening Schedule.Descriptive statistics,Pearson correlation analyses,and chain mediation analysis using the bootstrap method were performed.RESULTS Chronotype was significantly associated with both depression and anxiety.Sleep quality and social functioning significantly mediated these relationships.The indirect effect on depression was-0.52,accounting for 69.3%of the total effect.For anxiety, the indirect effect was -0.39, accounting for 79.3%. No significant direct effect of chronotype on depressionor anxiety was found after accounting for the mediators.CONCLUSIONSleep quality and social functioning mediate the association between chronotype and adolescent mental health.These findings highlight the importance of addressing sleep disturbances and social functioning impairments ininterventions aimed at improving mental well-being among adolescents with evening chronotypes.展开更多
This article discusses the importance of addressing social functioning impairment in patients with residual depressive symptoms,as highlighted in the study by Liao et al.The authors showed that social dysfunction pers...This article discusses the importance of addressing social functioning impairment in patients with residual depressive symptoms,as highlighted in the study by Liao et al.The authors showed that social dysfunction persists in many patients despite symptom remission.This observation calls for a shift in depression treatment strategies,with an emphasis on integrating social functioning as a key treatment goal.This article suggests targeted interventions that focus on both symptomatic relief and the restoration of social function.展开更多
The transition metal-catalyzed C–H activation have been considered as increasingly useful approach for installing new functional groups onto organic small molecules due to their high step-and atom-economy,the abundan...The transition metal-catalyzed C–H activation have been considered as increasingly useful approach for installing new functional groups onto organic small molecules due to their high step-and atom-economy,the abundance of hydrocarbon compounds,and the potential for late-stage functionalization of complex organic molecules.The ortho-and meta-C-H activation and functionalization of aromatic compounds have been widely explored in recent years,however the distal para-C-H activation and functionalization has remained a significant challenge because of the difficulty in forming energetically favorable metallacyclic transition states.The utilization of appropriate directing groups or templates as well as the meticulous design of catalysts and ligands has proven to be effective in transition-metal-catalyzed remote para-C-H bonds activation and functionalization of aromatic compounds.This review aims to summarize the strategies for controlling para-selective C–H functionalization using the directing group,template engineering,and catalyst/ligand design under transition metals catalysis in recent years.展开更多
The concepts of Markov process in random environment and homogeneous random transition functions are introduced. The necessary and sufficient conditions for homogeneous random transition function are given. The main r...The concepts of Markov process in random environment and homogeneous random transition functions are introduced. The necessary and sufficient conditions for homogeneous random transition function are given. The main results in this article are the analytical properties, such as continuity, differentiability, random Kolmogorov backward equation and random Kolmogorov forward equation of homogeneous random transition functions.展开更多
In China, rural settlements are usually multifunctional complex of natural societies and they also play important productive function. This study explored the spatiotemporal evolution of the productive function of thr...In China, rural settlements are usually multifunctional complex of natural societies and they also play important productive function. This study explored the spatiotemporal evolution of the productive function of three rural settlements, i.e.,Hetaoyuan, Dawengshan, and Gaoqiao, in the Yimeng Mountain in Shandong province of eastern China.Residents lived in this three types of rural settlements were all involved in agricultural production(i.e., grain threshing, drying and storage), which had remained dominant in Hetaoyuan. Dawengshan became an industrial-oriented settlement, while Gaoqiao became a commercial-oriented settlement. This evolution was reflected in the livelihood strategy changes of rural households and the transition of rural settlements changes. The choice of livelihood strategy was affected by the livelihood assets and policies, which resulted in the spatiotemporal evolution of the productive function of rural settlements. This study can provide references for the implementation and adjustment of rural residential land consolidation policies and the improvement of production and the quality of rural life in future.展开更多
We analyzed a total of 37 427 receiver-function data recorded by national and regional broadband seismic networks of the China Earthquake Administration to study the mantle transition zone beneath eastern and central ...We analyzed a total of 37 427 receiver-function data recorded by national and regional broadband seismic networks of the China Earthquake Administration to study the mantle transition zone beneath eastern and central China. Significant topography on both the 410-km and 660-km discontinuities was clearly imaged in the 3D volume of CCP （common-conversion-point） stacked images that cover an area of 102.5°F-122.5°E and 22.0°N-42.0°N. 3D crustal and mantle velocity models were used in computing the Ps time moveouts to better image the absolute depths of the two discontinuities. We found that the 660-km discontinuity is depressed up to 25 km along the east coast of China, indicating the presence of the subducted Pacific slab in the region. More interestingly, a double 660-km was observed beneath the Huanghai Sea, which was not seen from the 410-km discontinuity. We found a strong and localized anomaly beneath the Quaternary Datong volcano located at the northeastern edge of the Ordos Plateau in North China. The 410-km is depressed by as much as 15 km beneath the volcano. If the amount of the depression is caused by unmodeled low velocity anomaly in the upper mantle, it requires either a strong （4%-8%） localized low velocity anomaly near the lithosphere-asthenosphere boundary or -1.5% low velocity column across the entire upper mantle above the 410-km. The latter could suggest a deep origin of the Datong volcano, although it was usually attributed to edge-driven convection by most of the literatures.展开更多
The phase transition of gallium phosphide （GAP） from zinc-blende （ZB） to a rocksalt （RS） structure is investigated by the plane-wave pseudopotential density functional theory （DFT）. Lattice constant a0, elasti...The phase transition of gallium phosphide （GAP） from zinc-blende （ZB） to a rocksalt （RS） structure is investigated by the plane-wave pseudopotential density functional theory （DFT）. Lattice constant a0, elastic constants cij, bulk modulus B0 and the pressure derivative of bulk modulus B0 are calculated. The results are in good agreement with numerous experimental and theoretical data. From the usual condition of equal enthalpies, the phase transition from the ZB to the RS structure occurs at 21.9 GPa, which is close to the experimental value of 22.0 GPa. The elastic properties of GaP with the ZB structure in a pressure range from 0 GPa to 21.9 GPa and those of the RS structure in a pressure range of pressures from 21.9 GPa to 40 GPa are obtained. According to the quasi-harmonic Debye model, in which the phononic effects are considered, the normalized volume V/Vo, the Debye temperature 8, the heat capacity Cv and the thermal expansion coefficient a are also discussed in a pressure range from 0 CPa to 40 GPa and a temperature range from 0 K to 1500 K.展开更多
BACKGROUND Patients with schizophrenia may have various disease manifestations,most of which gradually tend toward incurable chronic decline,leading to mental disability.The basic symptoms of the disease can impair so...BACKGROUND Patients with schizophrenia may have various disease manifestations,most of which gradually tend toward incurable chronic decline,leading to mental disability.The basic symptoms of the disease can impair social function,whereas long-term hospitalization produces hospitalization syndrome,causing serious damage to social function.AIM To investigate the effects of Computerized Cognitive Remediation Therapy(CCRT)on cognitive and social functioning in patients with chronic schizophrenia.METHODS A retrospective analysis of 120 patients with chronic schizophrenia in Shanghai Pudong New Area Mental Health Center was performed.They were divided into an intervention group(60 cases treated with CCRT combined with conventional medication)and a control group(60 cases treated with conventional medication).After treatment,effects on cognitive function and social roles were observed in both groups.The Positive and Negative Syndrome Scale(PANSS)was used to assess the patients'psychiatric symptoms.The Wisconsin Card Sorting Test(WCST)was used to assess the patients'cognitive functioning,and the Social Functioning Scale for Psychiatric Inpatients(SSPI)was used to assess the social functioning of the inpatient psychiatric patients.RESULTS No significant differences were observed in the PANSS,WCST,and SSPI intergroup scores before treatment(P>0.05).After 2,4,and 6 wk of therapy,general psychopathological factors,positive symptoms,negative symptoms,and total PANSS scores of PANSS in the intervention group were lower than in the control group(P<0.05).After 2,4,and 6 wk of treatment,the number of false responses,number of persistent bugs,and total responses in the WCST were significantly lower in the intervention group than in the control group(P<0.05),and the amount of completed classification was significantly higher than in the control group(P<0.05).After 2,4,and 6 wk of therapy,the SSPI scores were significantly greater than those of the controls(P<0.05).After 6 wk of treatment,the efficacy rates of the control and intervention groups were 81.67%and 91.67%,respectively.The curative effect in the intervention group was significantly higher than that in the control group(P<0.05).CONCLUSION CCRT can significantly improve cognitive function and social abilities in patients with chronic schizophrenia.展开更多
This paper uses the generalised gradient approximation based on density functional theory to analyse the geometric structure and properties of the 3d transition metal atom doped endohedral fullerene M@C20F20 （M = Sc...This paper uses the generalised gradient approximation based on density functional theory to analyse the geometric structure and properties of the 3d transition metal atom doped endohedral fullerene M@C20F20 （M = Sc-Ni）. The geometric optimization shows that the cage centre is the most stable position for M, forming the structure named as M@C20F20-4. The inclusion energy, zero-point energy, and energy gap calculations tell us that Ni@C20F20-4 should be thermodynamically and kinetically stablest. M@C20F20-4 （M = Sc-Co） possesses high magnetic moments varied from 1 to 6 μB, while Ni@C20F20-4 is nonmagnetic. The Ni-C bond in Ni@C20F20-4 contains both the covalent and ionic characters.展开更多
This work uses a block copolymer architecture[(A′B)nA2]m to unify the scattering function and spinodal transition of typical AB-type block copolymers.The key roles of block number,junction points and asymmetry ratios...This work uses a block copolymer architecture[(A′B)nA2]m to unify the scattering function and spinodal transition of typical AB-type block copolymers.The key roles of block number,junction points and asymmetry ratios of block length are(1)to determine the form factor of each block copolymer at the molecular scale;(2)to affect the entropy loss across the spinodal transition and may result in deflection of spinodal curves.The common features are validated in typical linear and nonlinear block copolymers,including AB diblock,asymmetric A′BA triblock,miktoarm stars of ABn,AnBn,(AB)n,(A′B)nA,A′BAm,and multi-graft combs of(BnA2)m and[(A′B)nA2]m.The explicit scattering functions and form factors of various block copolymers can be directly applied in radiation experiments(i.e.neutron or X-ray scattering)to unravel the effect of molecular architecture in solution and microphase separation in disordered melt.The molecular model used in this study is also helpful to guide the chemical synthesis to explore more potentially interesting block copolymers.展开更多
New requirements have been proposed for GIS practice teaching in colleges and universities in response to the developmental changes of national and industrial sectors during the social transition.Meanwhile,the underly...New requirements have been proposed for GIS practice teaching in colleges and universities in response to the developmental changes of national and industrial sectors during the social transition.Meanwhile,the underlying core characteristics of GIS should remain unchanged in GIS teaching to ensure they serve as the inherent attributes distinguishing GIS from other disciplines.Therefore,the clarification of the dialectical relationship between “changing” and “unchanging” in GIS practice teaching becomes the primary issue to address in relevant teaching reform.To address this issue,the present study systematically analyzes the structural contradictions in GIS practice teaching in the social transition period,and then closely examines the dialectical relationship between “changing” and “unchanging” from the key aspects of educational philosophy,teaching content,teaching methodology,and teaching assessment.Next,using the course of “GIS Practice Design” at the Central South University as an example,the present study describes this university’s reform and inheritance in GIS practice teaching,aiming to provide reference for GIS practice teaching in other universities or majors.展开更多
BACKGROUND Long-term treatment of attention deficit/hyperactivity disorder(ADHD)is associated with adverse events,such as nausea and vomiting,dizziness,and sleep disturbances,and poor maintenance of late ADHD medicati...BACKGROUND Long-term treatment of attention deficit/hyperactivity disorder(ADHD)is associated with adverse events,such as nausea and vomiting,dizziness,and sleep disturbances,and poor maintenance of late ADHD medication compromises treatment outcomes and prolongs the recovery of patients’social functioning.AIM To evaluate the effect of non-pharmacological treatment on the full recovery of social functioning in patients with ADHD.METHODS A total of 90 patients diagnosed with ADHD between May 2019 and August 2020 were included in the study and randomly assigned to either the pharmacological group(methylphenidate hydrochloride and tomoxetine hydrochloride)or the non-pharmacological group(parental training,behavior modification,sensory integration therapy,and sand tray therapy),with 45 cases in each group.Outcome measures included treatment compliance,Swanson,Nolan,and Pelham,Version IV(SNAP-IV)scores,Conners Parent Symptom Questionnaire(PSQ)scores,and Weiss Functional Impairment Rating Scale(WFIRS)scores.RESULTS The non-pharmacological interventions resulted in significantly higher compliance in patients(95.56%)compared with medication(71.11%)(P<0.05).However,no significant differences in SNAP-IV and PSQ scores,in addition to the learning/school,social activities,and adventure activities of the WFIRS scores were observed between the two groups(P>0.05).Patients with non-pharmacological interventions showed higher WFIRS scores for family,daily life skills,and self-concept than those in the pharmacological group(P<0.05).CONCLUSION Non-pharmacological interventions,in contrast to the potential risks of adverse events after longterm medication,improve patient treatment compliance,alleviate patients’behavioral symptoms of attention,impulsivity,and hyperactivity,and improve their cognitive ability,thereby improving family relationships and patient self-evaluation.展开更多
Sister Carrie and Dwelling depict two heroines who share similarities in many aspects. They all live in the social transitional period and suffer a lot. This paper will make a comparison about the two ladies' trag...Sister Carrie and Dwelling depict two heroines who share similarities in many aspects. They all live in the social transitional period and suffer a lot. This paper will make a comparison about the two ladies' tragic fates and aims to investigate the impact on females brought about by the social transition.展开更多
The aim of the study was to investigate the functional performance in children with spina bifida, using the Pediatric Evaluation of Disability Inventory （PEDI） to look into capacity of twen- ty-eight children with s...The aim of the study was to investigate the functional performance in children with spina bifida, using the Pediatric Evaluation of Disability Inventory （PEDI） to look into capacity of twen- ty-eight children with spina bifida with lesions at different levels in different dimensions of self- care, mobility and social function. Mean age of the patients was 3.5 ± 2.3 （1-10） years. In the muscle test carried out, 13 patients （44.8%） had no movements including pelvic elevation in lower extremity muscles and they were at level 5. Sixteen patients （54%） were non-ambulatory according to the Hoofer ambulation classification. Raw and scale scores in the self-care, mobil- ity and social function domains both in the functional skill scale and in the caregiver scale were found to be lower compared to the data of the normal population. A statistically significant correlation was observed in the self-care values of the Functional Skills Scales and the Caregiver Assistance Scale measurements, which was positive for age and negative for Functional Ambu- lation Scale and muscle test （P 〈 0.05）. A positive relation was found between the Functional Skills Scales-mobility area and age while a negative relation was observed between Functional Ambulation Scale and muscle test （P 〈 0.005）. A negative relation was also found between Care- giver Assistance Scale-mobility and Functional Ambulation Scale and muscle test （P 〈 0.005）. In our study, the functional performance of the children was found to be low. Low-level lesions, encouraging muscular strength and independence in mobility are all very important factors for functional independence.展开更多
Profile function properties with different variables are discussed, the formulae of stimulated absorption, spontaneous and stimulated emission, absorption and emission coefficients, and cross sections are deduced, and...Profile function properties with different variables are discussed, the formulae of stimulated absorption, spontaneous and stimulated emission, absorption and emission coefficients, and cross sections are deduced, and some confusing issues are clarified.展开更多
The adsorption of cyanide on the top site of a series of transition metal M（100） （M = Cu, Ag, Au, Ni, Pd, Pt） surfaces via carbon and nitrogen atoms respectively, with the CN axis perpendicular to the surface, has...The adsorption of cyanide on the top site of a series of transition metal M（100） （M = Cu, Ag, Au, Ni, Pd, Pt） surfaces via carbon and nitrogen atoms respectively, with the CN axis perpendicular to the surface, has been studied by means of density functional theory and cluster model. Geometry, adsorption energy and vibrational frequencies have been determined, and the present calculations show that the adsorption of CN through C-end on metal surface is more favorable than that via N-end for the same surface. The vibrational frequencies of CN for C-down configuration on surface are blue-shifted with respect to the free CN, which is contrary to the change of vibrational frequencies when CN is adsorbed by N-down structure. Furthermore, the charge transfer from surface to CN causes the increase of surface work function.展开更多
A functional integral approach (FIA) is introduced to calculate the transition temperature of a uniform imperfect Bose gas. With this approach we find that the transition temperature is higher than that of the corresp...A functional integral approach (FIA) is introduced to calculate the transition temperature of a uniform imperfect Bose gas. With this approach we find that the transition temperature is higher than that of the corresponding ideal gas. We obtain the expression of the transition temperature shift as , where n is the density of particle number and a is the scattering length. The result has never been reported in the literature.展开更多
The new reactions between o-hydroxyphenyl enaminones and Langlois reagent(CF_(3)SO_(2)Na)for the tunable synthesis of 3-(trifluoromethylthio)chromones and 3-trifluoromethylsulfinyl chromones are reported herein.Both t...The new reactions between o-hydroxyphenyl enaminones and Langlois reagent(CF_(3)SO_(2)Na)for the tunable synthesis of 3-(trifluoromethylthio)chromones and 3-trifluoromethylsulfinyl chromones are reported herein.Both type of reactions proceed under transition metal-free conditions.In addition,the conditions for the synthesis of 3-trifluoromethylsulfinyl chromones have also been found to be applicable for the synthesis of 3-alkyl/arylsulfinyl chromones.展开更多
This study proposes a social-financial approach(SFA)to fill the methodological research gap in strategic policy design for managing financial transitions during social changes.The SFA seeks to characterize inclusive t...This study proposes a social-financial approach(SFA)to fill the methodological research gap in strategic policy design for managing financial transitions during social changes.The SFA seeks to characterize inclusive transitions in response to innovation and analyze financial management in social changes.Using a multilevel perspective,we combine evolutionary finance and inclusive growth analytics into this framework.We contend that the interaction between the different levels can be summarized as spontaneous adjustments and the alignment of financial elements with the indicators.Actors who attempt to achieve their goals based on past performance evaluations and other forms of bounded rationality strive to cope with adjustments and further trigger a reorientation of the existing regime.We also developed a new configuration tool called the three-axis description to describe the evolution of financial transitions at different stages.These methods allow us to analyze the evolution of financial transition and efficiency,and we argue that market efficiency evolves in stages with the finan-cial transition.Finally,to demonstrate the capability of SFA to identify diverse financial transition pathways,we examined an example case:the establishment of the Bretton Woods System.展开更多
文摘BACKGROUND At present,the influencing factors of social function in patients with residual depressive symptoms are still unclear.Residual depressive symptoms are highly harmful,leading to low mood in patients,affecting work and interpersonal communication,increasing the risk of recurrence,and adding to the burden on families.Studying the influencing factors of their social function is of great significance.AIM To explore the social function score and its influencing factors in patients with residual depressive symptoms.METHODS This observational study surveyed patients with residual depressive symptoms(case group)and healthy patients undergoing physical examinations(control group).Participants were admitted between January 2022 and December 2023.Social functioning was assessed using the Sheehan Disability Scale(SDS),and scores were compared between groups.Factors influencing SDS scores in patients with residual depressive symptoms were analyzed by applying multiple linear regression while using the receiver operating characteristic curve,and these RESULTS The SDS scores of the 158 patients with depressive symptoms were 11.48±3.26.Compared with the control group,the SDS scores and all items in the case group were higher.SDS scores were higher in patients with relapse,discon-tinuous medication,drug therapy alone,severe somatic symptoms,obvious residual symptoms,and anxiety scores≥8.Disease history,medication compliance,therapy method,and residual symptoms correlated positively with SDS scores(r=0.354,0.414,0.602,and 0.456,respectively).Independent influencing factors included disease history,medication compliance,therapy method,somatic symptoms,residual symptoms,and anxiety scores(P<0.05).The areas under the curve for predicting social functional impairment using these factors were 0.713,0.559,0.684,0.729,0.668,and 0.628,respectively,with sensitivities of 79.2%,61.8%,76.8%,81.7%,63.6%,and 65.5%and specificities of 83.3%,87.5%,82.6%,83.3%,86.7%,and 92.1%,respectively.CONCLUSION The social function scores of patients with residual symptoms of depression are high.They are affected by disease history,medication compliance,therapy method,degree of somatic symptoms,residual symptoms,and anxiety.
文摘BACKGROUND Adolescents with an evening chronotype are at higher risk for mental health problems,such as depression and anxiety.However,the mechanisms underlying this relationship are not well understood.Sleep disturbances and impaired social functioning may mediate this association.AIM To examine the mediating roles of sleep quality and social functioning in the relationship between chronotype and mental health in adolescents.METHODS A cross-sectional survey was conducted among 381 adolescents(mean age 14.3 years;61.9%male)using the Morningness-Eveningness Questionnaire,Hamilton Depression Rating Scale,Hamilton Anxiety Scale,Pittsburgh Sleep Quality Index,and Social Disability Screening Schedule.Descriptive statistics,Pearson correlation analyses,and chain mediation analysis using the bootstrap method were performed.RESULTS Chronotype was significantly associated with both depression and anxiety.Sleep quality and social functioning significantly mediated these relationships.The indirect effect on depression was-0.52,accounting for 69.3%of the total effect.For anxiety, the indirect effect was -0.39, accounting for 79.3%. No significant direct effect of chronotype on depressionor anxiety was found after accounting for the mediators.CONCLUSIONSleep quality and social functioning mediate the association between chronotype and adolescent mental health.These findings highlight the importance of addressing sleep disturbances and social functioning impairments ininterventions aimed at improving mental well-being among adolescents with evening chronotypes.
文摘This article discusses the importance of addressing social functioning impairment in patients with residual depressive symptoms,as highlighted in the study by Liao et al.The authors showed that social dysfunction persists in many patients despite symptom remission.This observation calls for a shift in depression treatment strategies,with an emphasis on integrating social functioning as a key treatment goal.This article suggests targeted interventions that focus on both symptomatic relief and the restoration of social function.
基金support from the National Natural Science Foundation of China(No.21901206)Postdoctoral Science Foundation of China(No.2022M712589)+2 种基金General Key R&D Projects in Shaanxi Province(No.2023-YBGY-321)Natural Science Foundation of Chongqing(No.CSTB2022NSCQ-MSX0826)National&Local Joint Engineering Research Center for mineral Salt Deep Utilization,Huaiyin Institute of Technology(No.SF202407)for financial support。
文摘The transition metal-catalyzed C–H activation have been considered as increasingly useful approach for installing new functional groups onto organic small molecules due to their high step-and atom-economy,the abundance of hydrocarbon compounds,and the potential for late-stage functionalization of complex organic molecules.The ortho-and meta-C-H activation and functionalization of aromatic compounds have been widely explored in recent years,however the distal para-C-H activation and functionalization has remained a significant challenge because of the difficulty in forming energetically favorable metallacyclic transition states.The utilization of appropriate directing groups or templates as well as the meticulous design of catalysts and ligands has proven to be effective in transition-metal-catalyzed remote para-C-H bonds activation and functionalization of aromatic compounds.This review aims to summarize the strategies for controlling para-selective C–H functionalization using the directing group,template engineering,and catalyst/ligand design under transition metals catalysis in recent years.
基金Supported by the NNSF of China (10371092)the Foundation of Wuhan University.
文摘The concepts of Markov process in random environment and homogeneous random transition functions are introduced. The necessary and sufficient conditions for homogeneous random transition function are given. The main results in this article are the analytical properties, such as continuity, differentiability, random Kolmogorov backward equation and random Kolmogorov forward equation of homogeneous random transition functions.
基金supported by the National Natural Science Foundation of China(Grant Nos.41671519 and 41771560)
文摘In China, rural settlements are usually multifunctional complex of natural societies and they also play important productive function. This study explored the spatiotemporal evolution of the productive function of three rural settlements, i.e.,Hetaoyuan, Dawengshan, and Gaoqiao, in the Yimeng Mountain in Shandong province of eastern China.Residents lived in this three types of rural settlements were all involved in agricultural production(i.e., grain threshing, drying and storage), which had remained dominant in Hetaoyuan. Dawengshan became an industrial-oriented settlement, while Gaoqiao became a commercial-oriented settlement. This evolution was reflected in the livelihood strategy changes of rural households and the transition of rural settlements changes. The choice of livelihood strategy was affected by the livelihood assets and policies, which resulted in the spatiotemporal evolution of the productive function of rural settlements. This study can provide references for the implementation and adjustment of rural residential land consolidation policies and the improvement of production and the quality of rural life in future.
文摘We analyzed a total of 37 427 receiver-function data recorded by national and regional broadband seismic networks of the China Earthquake Administration to study the mantle transition zone beneath eastern and central China. Significant topography on both the 410-km and 660-km discontinuities was clearly imaged in the 3D volume of CCP （common-conversion-point） stacked images that cover an area of 102.5°F-122.5°E and 22.0°N-42.0°N. 3D crustal and mantle velocity models were used in computing the Ps time moveouts to better image the absolute depths of the two discontinuities. We found that the 660-km discontinuity is depressed up to 25 km along the east coast of China, indicating the presence of the subducted Pacific slab in the region. More interestingly, a double 660-km was observed beneath the Huanghai Sea, which was not seen from the 410-km discontinuity. We found a strong and localized anomaly beneath the Quaternary Datong volcano located at the northeastern edge of the Ordos Plateau in North China. The 410-km is depressed by as much as 15 km beneath the volcano. If the amount of the depression is caused by unmodeled low velocity anomaly in the upper mantle, it requires either a strong （4%-8%） localized low velocity anomaly near the lithosphere-asthenosphere boundary or -1.5% low velocity column across the entire upper mantle above the 410-km. The latter could suggest a deep origin of the Datong volcano, although it was usually attributed to edge-driven convection by most of the literatures.
文摘The phase transition of gallium phosphide （GAP） from zinc-blende （ZB） to a rocksalt （RS） structure is investigated by the plane-wave pseudopotential density functional theory （DFT）. Lattice constant a0, elastic constants cij, bulk modulus B0 and the pressure derivative of bulk modulus B0 are calculated. The results are in good agreement with numerous experimental and theoretical data. From the usual condition of equal enthalpies, the phase transition from the ZB to the RS structure occurs at 21.9 GPa, which is close to the experimental value of 22.0 GPa. The elastic properties of GaP with the ZB structure in a pressure range from 0 GPa to 21.9 GPa and those of the RS structure in a pressure range of pressures from 21.9 GPa to 40 GPa are obtained. According to the quasi-harmonic Debye model, in which the phononic effects are considered, the normalized volume V/Vo, the Debye temperature 8, the heat capacity Cv and the thermal expansion coefficient a are also discussed in a pressure range from 0 CPa to 40 GPa and a temperature range from 0 K to 1500 K.
基金Supported by Shanghai Pudong New Area Science and Technology Development and Livelihood Research Special Fund Support Project,No.PKJ2023-Y80Integrated Traditional Chinese and Western Medicine Specialized Disease Diagnosis and Treatment Center Project,No.PDZY-2022-05-01.
文摘BACKGROUND Patients with schizophrenia may have various disease manifestations,most of which gradually tend toward incurable chronic decline,leading to mental disability.The basic symptoms of the disease can impair social function,whereas long-term hospitalization produces hospitalization syndrome,causing serious damage to social function.AIM To investigate the effects of Computerized Cognitive Remediation Therapy(CCRT)on cognitive and social functioning in patients with chronic schizophrenia.METHODS A retrospective analysis of 120 patients with chronic schizophrenia in Shanghai Pudong New Area Mental Health Center was performed.They were divided into an intervention group(60 cases treated with CCRT combined with conventional medication)and a control group(60 cases treated with conventional medication).After treatment,effects on cognitive function and social roles were observed in both groups.The Positive and Negative Syndrome Scale(PANSS)was used to assess the patients'psychiatric symptoms.The Wisconsin Card Sorting Test(WCST)was used to assess the patients'cognitive functioning,and the Social Functioning Scale for Psychiatric Inpatients(SSPI)was used to assess the social functioning of the inpatient psychiatric patients.RESULTS No significant differences were observed in the PANSS,WCST,and SSPI intergroup scores before treatment(P>0.05).After 2,4,and 6 wk of therapy,general psychopathological factors,positive symptoms,negative symptoms,and total PANSS scores of PANSS in the intervention group were lower than in the control group(P<0.05).After 2,4,and 6 wk of treatment,the number of false responses,number of persistent bugs,and total responses in the WCST were significantly lower in the intervention group than in the control group(P<0.05),and the amount of completed classification was significantly higher than in the control group(P<0.05).After 2,4,and 6 wk of therapy,the SSPI scores were significantly greater than those of the controls(P<0.05).After 6 wk of treatment,the efficacy rates of the control and intervention groups were 81.67%and 91.67%,respectively.The curative effect in the intervention group was significantly higher than that in the control group(P<0.05).CONCLUSION CCRT can significantly improve cognitive function and social abilities in patients with chronic schizophrenia.
基金Project supported by the Research Starting Foundation of Hohai University (Grant No. 2084/40801130)the Natural Science Foundation of Hohai University (Grant Nos. 2008431211 and 2008430311)+2 种基金the Excellent Innovation Personal Support Plan of Hohai Universitythe Basic Scientific Research Foundation of National Centralthe Special Foundation of the Natural Natural Science (Grant No. 10947132)
文摘This paper uses the generalised gradient approximation based on density functional theory to analyse the geometric structure and properties of the 3d transition metal atom doped endohedral fullerene M@C20F20 （M = Sc-Ni）. The geometric optimization shows that the cage centre is the most stable position for M, forming the structure named as M@C20F20-4. The inclusion energy, zero-point energy, and energy gap calculations tell us that Ni@C20F20-4 should be thermodynamically and kinetically stablest. M@C20F20-4 （M = Sc-Co） possesses high magnetic moments varied from 1 to 6 μB, while Ni@C20F20-4 is nonmagnetic. The Ni-C bond in Ni@C20F20-4 contains both the covalent and ionic characters.
基金by the Fundamental Research Funds for the Central Universities,Nankai University(No.000082)the National Natural Science Foundation of China(No.21973050).
文摘This work uses a block copolymer architecture[(A′B)nA2]m to unify the scattering function and spinodal transition of typical AB-type block copolymers.The key roles of block number,junction points and asymmetry ratios of block length are(1)to determine the form factor of each block copolymer at the molecular scale;(2)to affect the entropy loss across the spinodal transition and may result in deflection of spinodal curves.The common features are validated in typical linear and nonlinear block copolymers,including AB diblock,asymmetric A′BA triblock,miktoarm stars of ABn,AnBn,(AB)n,(A′B)nA,A′BAm,and multi-graft combs of(BnA2)m and[(A′B)nA2]m.The explicit scattering functions and form factors of various block copolymers can be directly applied in radiation experiments(i.e.neutron or X-ray scattering)to unravel the effect of molecular architecture in solution and microphase separation in disordered melt.The molecular model used in this study is also helpful to guide the chemical synthesis to explore more potentially interesting block copolymers.
基金Teaching Reform Project of Central South University(No.2022jy001-2)Higher Education Teaching Reform Project of Hunan Province(No.HNJG-2022-0025)。
文摘New requirements have been proposed for GIS practice teaching in colleges and universities in response to the developmental changes of national and industrial sectors during the social transition.Meanwhile,the underlying core characteristics of GIS should remain unchanged in GIS teaching to ensure they serve as the inherent attributes distinguishing GIS from other disciplines.Therefore,the clarification of the dialectical relationship between “changing” and “unchanging” in GIS practice teaching becomes the primary issue to address in relevant teaching reform.To address this issue,the present study systematically analyzes the structural contradictions in GIS practice teaching in the social transition period,and then closely examines the dialectical relationship between “changing” and “unchanging” from the key aspects of educational philosophy,teaching content,teaching methodology,and teaching assessment.Next,using the course of “GIS Practice Design” at the Central South University as an example,the present study describes this university’s reform and inheritance in GIS practice teaching,aiming to provide reference for GIS practice teaching in other universities or majors.
基金Supported by Ningbo Science and Technology Plan Project Public Welfare Plan(Municipal Level),No:2019C50099Ningbo Medical Key Supporting Discipline Child Health Science,No:2022-F26。
文摘BACKGROUND Long-term treatment of attention deficit/hyperactivity disorder(ADHD)is associated with adverse events,such as nausea and vomiting,dizziness,and sleep disturbances,and poor maintenance of late ADHD medication compromises treatment outcomes and prolongs the recovery of patients’social functioning.AIM To evaluate the effect of non-pharmacological treatment on the full recovery of social functioning in patients with ADHD.METHODS A total of 90 patients diagnosed with ADHD between May 2019 and August 2020 were included in the study and randomly assigned to either the pharmacological group(methylphenidate hydrochloride and tomoxetine hydrochloride)or the non-pharmacological group(parental training,behavior modification,sensory integration therapy,and sand tray therapy),with 45 cases in each group.Outcome measures included treatment compliance,Swanson,Nolan,and Pelham,Version IV(SNAP-IV)scores,Conners Parent Symptom Questionnaire(PSQ)scores,and Weiss Functional Impairment Rating Scale(WFIRS)scores.RESULTS The non-pharmacological interventions resulted in significantly higher compliance in patients(95.56%)compared with medication(71.11%)(P<0.05).However,no significant differences in SNAP-IV and PSQ scores,in addition to the learning/school,social activities,and adventure activities of the WFIRS scores were observed between the two groups(P>0.05).Patients with non-pharmacological interventions showed higher WFIRS scores for family,daily life skills,and self-concept than those in the pharmacological group(P<0.05).CONCLUSION Non-pharmacological interventions,in contrast to the potential risks of adverse events after longterm medication,improve patient treatment compliance,alleviate patients’behavioral symptoms of attention,impulsivity,and hyperactivity,and improve their cognitive ability,thereby improving family relationships and patient self-evaluation.
文摘Sister Carrie and Dwelling depict two heroines who share similarities in many aspects. They all live in the social transitional period and suffer a lot. This paper will make a comparison about the two ladies' tragic fates and aims to investigate the impact on females brought about by the social transition.
文摘The aim of the study was to investigate the functional performance in children with spina bifida, using the Pediatric Evaluation of Disability Inventory （PEDI） to look into capacity of twen- ty-eight children with spina bifida with lesions at different levels in different dimensions of self- care, mobility and social function. Mean age of the patients was 3.5 ± 2.3 （1-10） years. In the muscle test carried out, 13 patients （44.8%） had no movements including pelvic elevation in lower extremity muscles and they were at level 5. Sixteen patients （54%） were non-ambulatory according to the Hoofer ambulation classification. Raw and scale scores in the self-care, mobil- ity and social function domains both in the functional skill scale and in the caregiver scale were found to be lower compared to the data of the normal population. A statistically significant correlation was observed in the self-care values of the Functional Skills Scales and the Caregiver Assistance Scale measurements, which was positive for age and negative for Functional Ambu- lation Scale and muscle test （P 〈 0.05）. A positive relation was found between the Functional Skills Scales-mobility area and age while a negative relation was observed between Functional Ambulation Scale and muscle test （P 〈 0.005）. A negative relation was also found between Care- giver Assistance Scale-mobility and Functional Ambulation Scale and muscle test （P 〈 0.005）. In our study, the functional performance of the children was found to be low. Low-level lesions, encouraging muscular strength and independence in mobility are all very important factors for functional independence.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.51172236,51272254,51102239,61205173,and 61405206)
文摘Profile function properties with different variables are discussed, the formulae of stimulated absorption, spontaneous and stimulated emission, absorption and emission coefficients, and cross sections are deduced, and some confusing issues are clarified.
基金the National Natural Science Foundation of China (20673019, 20773024)the Natural Science Foundation of Fujian Province (U0650012)the New Century Excellent Talents in University and the Initial Funding for Talents of Fuzhou University (2008-XQ-07, XRC-0732)
文摘The adsorption of cyanide on the top site of a series of transition metal M（100） （M = Cu, Ag, Au, Ni, Pd, Pt） surfaces via carbon and nitrogen atoms respectively, with the CN axis perpendicular to the surface, has been studied by means of density functional theory and cluster model. Geometry, adsorption energy and vibrational frequencies have been determined, and the present calculations show that the adsorption of CN through C-end on metal surface is more favorable than that via N-end for the same surface. The vibrational frequencies of CN for C-down configuration on surface are blue-shifted with respect to the free CN, which is contrary to the change of vibrational frequencies when CN is adsorbed by N-down structure. Furthermore, the charge transfer from surface to CN causes the increase of surface work function.
文摘A functional integral approach (FIA) is introduced to calculate the transition temperature of a uniform imperfect Bose gas. With this approach we find that the transition temperature is higher than that of the corresponding ideal gas. We obtain the expression of the transition temperature shift as , where n is the density of particle number and a is the scattering length. The result has never been reported in the literature.
基金financially supported by National Natural Science Foundation of China(No.22161022)。
文摘The new reactions between o-hydroxyphenyl enaminones and Langlois reagent(CF_(3)SO_(2)Na)for the tunable synthesis of 3-(trifluoromethylthio)chromones and 3-trifluoromethylsulfinyl chromones are reported herein.Both type of reactions proceed under transition metal-free conditions.In addition,the conditions for the synthesis of 3-trifluoromethylsulfinyl chromones have also been found to be applicable for the synthesis of 3-alkyl/arylsulfinyl chromones.
文摘This study proposes a social-financial approach(SFA)to fill the methodological research gap in strategic policy design for managing financial transitions during social changes.The SFA seeks to characterize inclusive transitions in response to innovation and analyze financial management in social changes.Using a multilevel perspective,we combine evolutionary finance and inclusive growth analytics into this framework.We contend that the interaction between the different levels can be summarized as spontaneous adjustments and the alignment of financial elements with the indicators.Actors who attempt to achieve their goals based on past performance evaluations and other forms of bounded rationality strive to cope with adjustments and further trigger a reorientation of the existing regime.We also developed a new configuration tool called the three-axis description to describe the evolution of financial transitions at different stages.These methods allow us to analyze the evolution of financial transition and efficiency,and we argue that market efficiency evolves in stages with the finan-cial transition.Finally,to demonstrate the capability of SFA to identify diverse financial transition pathways,we examined an example case:the establishment of the Bretton Woods System.
