It is well known that aluminum and copper exhibit structural phase transformations in quasi-static and dynamic measurements,including shock wave loading.However,the dependence of phase transformations in a wide range ...It is well known that aluminum and copper exhibit structural phase transformations in quasi-static and dynamic measurements,including shock wave loading.However,the dependence of phase transformations in a wide range of crystallographic directions of shock loading has not been revealed.In this work,we calculated the shock Hugoniot for aluminum and copper in different crystallographic directions([100],[110],[111],[112],[102],[114],[123],[134],[221]and[401])of shock compression using molecular dynamics(MD)simulations.The results showed a high pressure(>160 GPa for Cu and>40 GPa for Al)of the FCC-to-BCC transition.In copper,different characteristics of the phase transition are observed depending on the loading direction with the[100]compression direction being the weakest.The FCC-to-BCC transition for copper is in the range of 150–220 GPa,which is consistent with the existing experimental data.Due to the high transition pressure,the BCC phase transition in copper competes with melting.In aluminum,the FCC-to-BCC transition is observed for all studied directions at pressures between 40 and 50 GPa far beyond the melting.In all considered cases we observe the coexistence of HCP and BCC phases during the FCC-to-BCC transition,which is consistent with the experimental data and atomistic calculations;this HCP phase forms in the course of accompanying plastic deformation with dislocation activity in the parent FCC phase.The plasticity incipience is also anisotropic in bothmetals,which is due to the difference in the projections of stress on the slip plane for different orientations of the FCC crystal.MD modeling results demonstrate a strong dependence of the FCC-to-BCC transition on the crystallographic direction,in which the material is loaded in the copper crystals.However,MD simulations data can only be obtained for specific points in the stereographic direction space;therefore,for more comprehensive understanding of the phase transition process,a feed-forward neural network was trained using MD modeling data.The trained machine learning model allowed us to construct continuous stereographic maps of phase transitions as a function of stress in the shock-compressed state of metal.Due to appearance and growth of multiple centers of new phase,the FCC-to-BCC transition leads to formation of a polycrystalline structure from the parent single crystal.展开更多
The moment a media delegation from the Republic of the Congo arrived at the Othello Kitchenware Museum on 18 November 2025,they were greeted with a vivid show of Guangdong’s industrial strength.Standing before them w...The moment a media delegation from the Republic of the Congo arrived at the Othello Kitchenware Museum on 18 November 2025,they were greeted with a vivid show of Guangdong’s industrial strength.Standing before them was not a typical exhibition hall,but a building shaped like a gleaming stainless-steel cooking pot.展开更多
In the era of intelligent media,the interaction between teachers and students in higher education is undergoing a profound transformation.The model has shifted from one-way transmission to multi-agent,two-way collabor...In the era of intelligent media,the interaction between teachers and students in higher education is undergoing a profound transformation.The model has shifted from one-way transmission to multi-agent,two-way collaboration involving“teacher-student-AI(artificial intelligence)”.Interaction depth moves from surface Q&A to deep thought engagement,supported by instant,precise feedback and a blended virtual-physical space.New forms such as data-driven personalized interaction and immersive collaborative learning have emerged.However,this evolution brings significant challenges:over-reliance on technology may weaken cognitive autonomy;virtual interaction risks emotional detachment and trust erosion;ethical concerns like algorithmic bias and data privacy arise;teachers’roles become blurred;and evaluation systems lag behind technological advances.Future pathways should position AI as a supportive tool while upholding human centrality.Strengthening emotional connection through online-offline blending,reforming assessment to value process and growth,and empowering teachers as digitally literate“learning guides”and“emotional connectors”are key to building a healthy,sustainable interactive ecosystem.展开更多
In the past few decades,China's foreign trade,leveraging its comprehensive industrial system,resilient supply chain,and factor cost advantages,has steadily constructed a global division of labor pattern as the“wo...In the past few decades,China's foreign trade,leveraging its comprehensive industrial system,resilient supply chain,and factor cost advantages,has steadily constructed a global division of labor pattern as the“world's factory”.展开更多
BACKGROUND Acinar cystic transformation(ACT)of the pancreas is a rare non-neoplastic transformation of the pancreas.Adult women are the majority of patients with ACT,but few cases have been reported in pediatric patie...BACKGROUND Acinar cystic transformation(ACT)of the pancreas is a rare non-neoplastic transformation of the pancreas.Adult women are the majority of patients with ACT,but few cases have been reported in pediatric patients.Given that there are currently no guidelines for the treatment of ACT,current treatment is based primarily on expert opinions and clinical experiences.Here,we report the case of the youngest child with ACT to date.Additionally,a literature review on pediatric ACT cases was performed to summarize previous clinical experience and treatment methods.CASE SUMMARY A 1-year-old Chinese girl presented with progressive abdominal distension for 6 months.A detailed consultation revealed an uneventful history.The patient showed no signs of fever or abdominal pain and had a good appetite and normal feces.A mass of about 20 cm×10 cm×10 cm in size was detected in the abdomen.Both abdominal ultrasound and computed tomography examination revealed a multilocular cystic mass about 21.7 cm×16.8 cm×8.9 cm in size.At first,due to the large size and the possible retroperitoneal origin of the cyst,a total resection of the lesion was not possible.A single-port laparoscopic lymphangioma puncture and Pingyangmycin injection were performed in March 2023.One month after surgery,the abdominal cyst rapidly enlarged to its pre-operative size.After consulting with the experts in the angiology department and interventional department,sclerotherapy combined with oral sirolimus was performed in May 2023.After confirming that the tumor was not sensitive to sclerotherapy combined with oral sirolimus,our surgical team performed tumor reduction in August 2023.This surgery confirmed that the polycystic mass originated from the head of the pancreas,and pathological and immunohistochemical findings diagnosed pancreatic ACT.The patient showed no signs of cyst lesions after 6 months of follow-up and remains in good health up to the time of this report.CONCLUSION ACT is a rare non-neoplastic transformation of the pancreas,more rarely seen in children.Manifestation and examinations show no specificity for diagnosis,and final diagnosis is mainly based on histological findings.To reach a specific diagnosis and rule out malignancy is a priority in clinical practice,and repeated biopsy or radical surgery should be considered before malignancy is ruled out.However,once a diagnosis of ACT is made,a conser-vative treatment with consecutive follow-up is recommended until symptoms present or obvious enlargement occurs because ACT is considered a slow-growing and benign tumor.展开更多
Agrobacterium tumefaciens-mediated transformation has been widely adopted for plant genetic engineering and the study of gene function(Krenek et al.,2015).This method is prevalent in the genetic transformation of herb...Agrobacterium tumefaciens-mediated transformation has been widely adopted for plant genetic engineering and the study of gene function(Krenek et al.,2015).This method is prevalent in the genetic transformation of herbaceous plants,with notable applications in species such as Arabidopsis(Yin et al.,2024),soybean(Zhang et al.,2024),rice(Zhang et al.,2020),and Chinese cabbage(Li et al.,2021).However,its application in fruit trees is limited.This is primarily due to their long growth cycles and lack of rapid,efficient,and stable transgenic systems,which severely hinders foundational research involving plant genetic transformation(Mei et al.,2024).Furthermore,for subtropical fruit trees,the presence of recalcitrant seeds adds an extra layer of difficulty to genetic transformation(Umarani et al.,2015),as most methods rely on seed germination as a basis for transformation.展开更多
It is difficult to recover chrysocolla from sulfidation flotation which is closely related to the mineral surface composition.In this study,the effects of fluoride roasting on the surface composition of chrysocolla we...It is difficult to recover chrysocolla from sulfidation flotation which is closely related to the mineral surface composition.In this study,the effects of fluoride roasting on the surface composition of chrysocolla were investigated,its impact on sulfidation flotation was explored,and the mechanisms involved in both fluoride roasting and sulfidation flotation were discussed.With CaF_(2)as the roasting reagent,Na_(2)S·9H_(2)O as the sulfidation reagent,and sodium butyl xanthate(NaBX)as the collector,the results of the flotation experiments showed that fluoride roasting improved the floatability of chrysocolla,and the recovery rate increased from 16.87%to 82.74%.X-ray diffraction analysis revealed that after fluoride roasting,approximately all the Cu on the chrysocolla surface was exposed in the form of CuO,which could provide a basis for subsequent sulfidation flotation.The microscopy and elemental analyses revealed that large quantities of"pagoda-like"grains were observed on the sulfidation surface of the fluoride-roasted chrysocolla,indicating high crystallinity particles of copper sulfide.This suggests that the effect of sulfide formation on the chrysocolla surface was more pronounced.X-ray photoelectron spectroscopy revealed that fluoride roasting increased the relative contents of sulfur and copper on the surface and that both the Cu~+and polysulfide fractions on the surface of the minerals increased.This enhances the effect of sulfidation,which is conducive to flotation recovery.Therefore,fluoride roasting improved the effect of copper species transformation and sulfidation on the surface of chysocolla,promoted the adsorption of collectors,and improved the recovery of chrysocolla from sulfidation flotation.展开更多
The demand for Erigeron breviscapus,a medicinal Compositae plant with cardiovascular therapeutic properties,has been increasing by 15%annually,exceeding production capacity and necessitating improvements in yield and ...The demand for Erigeron breviscapus,a medicinal Compositae plant with cardiovascular therapeutic properties,has been increasing by 15%annually,exceeding production capacity and necessitating improvements in yield and bioactive compound content.Genetic transformation remains essential for functional genomics,yet current Agrobacterium and biolistic methods are inefficient and expensive.In this study,we cloned the full-length sequences of the BABY BOOM,WUSCHEL and GROWTH-REGULATING FACTOR(GRF)genes of E.breviscapus and then transformed them into E.breviscapus explants.The transformation efficiency for the GRF gene reached 45%,and all the transgenic E.breviscapus plants were fertile without obvious developmental defects.Furthermore,we inserted EbGRF4 and Cas9-EbPDS-sgRNA into the same vector for Agrobacterium-mediated transformation to effectively knock out the PDS gene,resulting in albino seedlings,with a gene editing efficiency of 33.3%.These findings provide a solid foundation for functional genomic research and the genetic improvement of E.breviscapus,as well as an important reference for establishing high-efficiency genetic transformation systems for other medicinal plants.展开更多
Peanuts(Arachis hypogaea) are important sources of vegetable oil,protein,and forage.The genus Arachis comprises nine intrageneric taxonomic sections encompassing 84 species.Most Arachis species are wild plants that se...Peanuts(Arachis hypogaea) are important sources of vegetable oil,protein,and forage.The genus Arachis comprises nine intrageneric taxonomic sections encompassing 84 species.Most Arachis species are wild plants that serve widely as forage and turfgrass.Furthermore,wild Arachis species provide valuable gene resources for broadening the genetic diversity of cultivated peanuts.To date,several key genes have been identified through the use of recombinant inbred lines derived from interspecific crosses within Arachis.Despite this progress,the application of genetic engineering to enhance peanut traits remains limited.This limitation arises primarily from the absence of a robust and reliable genetic transformation protocol for Arachis species.Nevertheless,evidence indicates that successful genetic transformation of Arachis plants was first reported approximately 30 years ago.Thus,a notable discrepancy exists between early reports of transformation success and the ongoing challenges in stably transferring candidate genes into Arachis genotypes.This review summarizes existing methods for regeneration and genetic transformation in Arachis,aiming to advance understanding of transgenic technologies applicable to this genus.展开更多
Using a quantum computer to simulate fermionic systems requires fermion-to-qubit transformations.Usually,lower Pauli weight of transformations means shallower quantum circuits.Therefore,most existing transformations a...Using a quantum computer to simulate fermionic systems requires fermion-to-qubit transformations.Usually,lower Pauli weight of transformations means shallower quantum circuits.Therefore,most existing transformations aim for lower Pauli weight.However,in some cases,the circuit depth depends not only on the Pauli weight but also on the coefficients of the Hamiltonian terms.In order to characterize the circuit depth of these algorithms,we propose a new metric called weighted Pauli weight,which depends on Pauli weight and coefficients of Hamiltonian terms.To achieve smaller weighted Pauli weight,we introduce a novel transformation,Huffman-code-based ternary tree(HTT)transformation,which is built upon the classical Huffman code and tailored to different Hamiltonians.We tested various molecular Hamiltonians and the results show that the weighted Pauli weight of the HTT transformation is smaller than that of commonly used mappings.At the same time,the HTT transformation also maintains a relatively small Pauli weight.The mapping we designed reduces the circuit depth of certain Hamiltonian simulation algorithms,facilitating faster simulation of fermionic systems.展开更多
The flow of a tetra-hybrid Casson nanofluid(Al_(2)O_(3)-CuO-TiO_(2)-Ag/H_(2)O)over a nonlinear stretching sheet is investigated.The Buongiorno model is used to account for thermophoresis and Brownian motion,while ther...The flow of a tetra-hybrid Casson nanofluid(Al_(2)O_(3)-CuO-TiO_(2)-Ag/H_(2)O)over a nonlinear stretching sheet is investigated.The Buongiorno model is used to account for thermophoresis and Brownian motion,while thermal radiation is incorporated to examine its influence on the thermal boundary layer.The governing partial differential equations(PDEs)are reduced to a system of nonlinear ordinary differential equations(ODEs)with fully non-dimensional similarity transformations involving all independent variables.To solve the obtained highly nonlinear system of differential equations,a novel Clique polynomial collocation method is applied.The analysis focuses on the effects of the Casson parameter,power index,radiation parameter,thermophoresis parameter,Brownian motion parameter,and Lewis number.The key findings show that thermal radiation intensifies the thermal boundary layer,the Casson parameter reduces the velocity,and the Lewis number suppresses the concentration with direct relevance to polymer processing,coating flows,electronic cooling,and biomedical applications.展开更多
On January 23,2026,the second plenary session of the China Expo Forum for International Cooperation(CEFCO) convened in Wuhan,Hubei Province.Amid significant changes in the global exhibition landscape,participants shar...On January 23,2026,the second plenary session of the China Expo Forum for International Cooperation(CEFCO) convened in Wuhan,Hubei Province.Amid significant changes in the global exhibition landscape,participants shared recent developments,key data,and future trends in major markets,offering guidance for industry practitioners to drive progress.展开更多
From lecture halls in Beijing to villages in the mountains of southwest China,a group of young rural innovators from Global South countries recently embarked on a journey that connected policy thinking,technological p...From lecture halls in Beijing to villages in the mountains of southwest China,a group of young rural innovators from Global South countries recently embarked on a journey that connected policy thinking,technological practice and lived rural experience.展开更多
With the theme of“standardized approaches empowering industrial green and low-carbon transformation”,a sub-forum was held to promote the application of the carbon footprint management system in China,advance the wid...With the theme of“standardized approaches empowering industrial green and low-carbon transformation”,a sub-forum was held to promote the application of the carbon footprint management system in China,advance the wide implementation of relevant standards,and accelerate the globalization process of green product trade through high-level communication.Lyu Xuefeng,Director of Qingdao Institute of Bioenergy and Bioprocess Technology(QIBEBT),Chinese Academy of Sciences,emphasized in his address that the product carbon footprint management system is the important support for industrial green transformation.The geographic information system-life cycle assessment(GIS-LCA)technology has been originally proposed and adopted as the core content of the national standard GB/T 24067-2024,Greenhouse gases-Carbon footprint of products-Requirements and guidelines for quantification.展开更多
The China Expo Forum for International Cooperation(CEFCO)2026 was held in Wuhan,Hubei Province,China,on January 22.The opening ceremony was attended by Li Qing Shuang,Vice President of the China Council for the Promot...The China Expo Forum for International Cooperation(CEFCO)2026 was held in Wuhan,Hubei Province,China,on January 22.The opening ceremony was attended by Li Qing Shuang,Vice President of the China Council for the Promotion of International Trade(CCPIT);Zhu Yuji,Deputy Secretary of the Hubei Provincial Committee of the Communist Party of China;Sheng Yue Chun,Member of the Standing Committee of the Hubei Provincial Committee of the Communist Party of China and Secretary of the Wuhan Municipal Committee;Punita Bhansal,President of the Global Association of the Exhibition Industry(UFI);Marsha Flanagan,President and CEO of the International Association of Exhibitions and Events(IAEE);Vincent Polito,CEO of the Society of Independent Show Organizers(SISO);and Leonie Ashford,Board Member of the International Congress and Convention Association(ICCA).展开更多
As the global economy has been undergoing profound changes and the industrial and supply chains have been restructuring rapidly,China International Supply Chain Expo(hereinafter referred to as the CISCE)emerged with t...As the global economy has been undergoing profound changes and the industrial and supply chains have been restructuring rapidly,China International Supply Chain Expo(hereinafter referred to as the CISCE)emerged with the time.展开更多
In-situ tensile tests were conducted on a chemically corroded third-generation single-crystal superalloy DD9 at 980 and 1100℃.The phase transformation in the surface areas during the tensile process was analyzed usin...In-situ tensile tests were conducted on a chemically corroded third-generation single-crystal superalloy DD9 at 980 and 1100℃.The phase transformation in the surface areas during the tensile process was analyzed using field emission scanning electron microscope,energy dispersive X-ray spectroscope,electron probe X-ray microanalysis,and transmission electron microscope.The phase transformation mechanism on the surface and the influence mechanism were studied through observation and dynamic calculation.During tensile tests at elevated temperatures,chemical corrosion promotes the precipitation of topologically close-packed(tcp)μphase andσphase on the alloy surface.Both the precipitation amount and size of these two phases on the surface at 1100℃are greater than those at 980℃.The precipitation of tcp phase on the alloy surface results in the formation of an influence layer on the surface area,and the distribution characteristics of alloying elements are significantly different from those of the substrate.The depth of the influence layer at 1100℃is greater than that at 980℃.The precipitation of tcp phase prompts the phase transition fromγphase toγ′phase around the tcp phase.展开更多
The world today is undergoing accelerated transformations unseen in a century.The international environment,fluid and volatile,is evolving in multiple dimensions beyond time and space.Faced with emerging and intensify...The world today is undergoing accelerated transformations unseen in a century.The international environment,fluid and volatile,is evolving in multiple dimensions beyond time and space.Faced with emerging and intensifying global challenges in the security,political,economic,technological and other fields,the international community has a pressing need to reshape the international landscape at this critical moment of change.展开更多
The accurate establishment of a ferrite transformation start temperature model is crucial to design a reasonable controlled rolling process and ensure uniform microstructure in aluminum bearing dual-phase steel.The me...The accurate establishment of a ferrite transformation start temperature model is crucial to design a reasonable controlled rolling process and ensure uniform microstructure in aluminum bearing dual-phase steel.The measurements of the expansion-temperature curves of aluminum bearing dual-phase steel under continuous cooling and isothermal conditions are presented,utilizing a dynamic transformation dilatometer experiment.Based on these expansion-temperature curves,the start temperature and incubation time of ferrite transformation were determined,elucidating the influence of process parameters on both the incubation time and the start temperature of ferrite transformation.By integrating metallurgical principles with measured incubation time of ferrite transformation,and considering the effects of temperature and strain,a fitting model for the variation in volume free energy during ferrite nucleation was derived.Building upon this foundation,a high-precision incubation time of ferrite transformation mathematical model for the experimental steel was established.To more accurately calculate the start temperature of ferrite transformation under continuous cooling conditions,the Scheil’s additivity rule was modified to account for the effects of deformation and cooling rate.The results indicate that the modification coefficient decreases with increasing the cooling rate and strain,thereby significantly improving the accuracy of calculating the starting temperature of ferrite transformation using the modified additivity rule.展开更多
Understanding the complex deformation mechanisms of non-equimolar multi-principal element alloys(MPEAs)requires high-fidelity atomic-scale simulations.This study develops a deep potential(DP)model to enable molecular ...Understanding the complex deformation mechanisms of non-equimolar multi-principal element alloys(MPEAs)requires high-fidelity atomic-scale simulations.This study develops a deep potential(DP)model to enable molecular dynamics simulations of the Ta_(0.4)Ti_(2)Zr(Ta_(0.4))alloy.Monte Carlo simulations using this potential reveal Ta atom precipitation in the Ta_(0.4)alloy.Under uniaxial tensile loading along the[100]direction in the NPT ensemble,the alloy undergoes a remarkable sequence of phase transformations:an initial body-centered cubic(BCC_(1))to face-centered cubic(FCC)transformation,followed by a reverse transformation from FCC to a distinct BCC phase(BCC_(2)),and finally a BCC_(2) to hexagonal close-packed(HCP)transformation.Critically,the reverse FCC to BCC_(2) transformation induces significant volume contraction.We demonstrate that the inversely transformed BCC_(2) phase primarily accommodates compressive stress.Concurrently,the reorientation of BCC_(2) crystals contributes substantially to the observed high strain hardening.These simulations provide atomic-scale insights into the dynamic structural evolution,sequential phase transformations,and stress partitioning during deformation of the Ta_(0.4)alloy.The developed DP model and the revealed mechanisms offer fundamental theoretical guidance for accelerating the design of high-performance MPEAs.展开更多
基金founded by the Ministry of Science and Higher Education of the Russian Federation,State assignments for research,registration No.1024032600084-8-1.3.2Study of the grain growth and the formation of polycrystalline structure as a result of phase transition(Section 6)was founded by the Russian Science Foundation,Project No.24-71-00078+3 种基金https://rscf.ru/en/project/24-71-00078/(accessed on 01 December 2025).Study of the orientation dependence of the phase transition of aluminum in Section 3 was founded by the Russian Science Foundation,Project No.24-19-00684https://rscf.ru/en/project/24-19-00684/(accessed on 01 December 2025).
文摘It is well known that aluminum and copper exhibit structural phase transformations in quasi-static and dynamic measurements,including shock wave loading.However,the dependence of phase transformations in a wide range of crystallographic directions of shock loading has not been revealed.In this work,we calculated the shock Hugoniot for aluminum and copper in different crystallographic directions([100],[110],[111],[112],[102],[114],[123],[134],[221]and[401])of shock compression using molecular dynamics(MD)simulations.The results showed a high pressure(>160 GPa for Cu and>40 GPa for Al)of the FCC-to-BCC transition.In copper,different characteristics of the phase transition are observed depending on the loading direction with the[100]compression direction being the weakest.The FCC-to-BCC transition for copper is in the range of 150–220 GPa,which is consistent with the existing experimental data.Due to the high transition pressure,the BCC phase transition in copper competes with melting.In aluminum,the FCC-to-BCC transition is observed for all studied directions at pressures between 40 and 50 GPa far beyond the melting.In all considered cases we observe the coexistence of HCP and BCC phases during the FCC-to-BCC transition,which is consistent with the experimental data and atomistic calculations;this HCP phase forms in the course of accompanying plastic deformation with dislocation activity in the parent FCC phase.The plasticity incipience is also anisotropic in bothmetals,which is due to the difference in the projections of stress on the slip plane for different orientations of the FCC crystal.MD modeling results demonstrate a strong dependence of the FCC-to-BCC transition on the crystallographic direction,in which the material is loaded in the copper crystals.However,MD simulations data can only be obtained for specific points in the stereographic direction space;therefore,for more comprehensive understanding of the phase transition process,a feed-forward neural network was trained using MD modeling data.The trained machine learning model allowed us to construct continuous stereographic maps of phase transitions as a function of stress in the shock-compressed state of metal.Due to appearance and growth of multiple centers of new phase,the FCC-to-BCC transition leads to formation of a polycrystalline structure from the parent single crystal.
文摘The moment a media delegation from the Republic of the Congo arrived at the Othello Kitchenware Museum on 18 November 2025,they were greeted with a vivid show of Guangdong’s industrial strength.Standing before them was not a typical exhibition hall,but a building shaped like a gleaming stainless-steel cooking pot.
文摘In the era of intelligent media,the interaction between teachers and students in higher education is undergoing a profound transformation.The model has shifted from one-way transmission to multi-agent,two-way collaboration involving“teacher-student-AI(artificial intelligence)”.Interaction depth moves from surface Q&A to deep thought engagement,supported by instant,precise feedback and a blended virtual-physical space.New forms such as data-driven personalized interaction and immersive collaborative learning have emerged.However,this evolution brings significant challenges:over-reliance on technology may weaken cognitive autonomy;virtual interaction risks emotional detachment and trust erosion;ethical concerns like algorithmic bias and data privacy arise;teachers’roles become blurred;and evaluation systems lag behind technological advances.Future pathways should position AI as a supportive tool while upholding human centrality.Strengthening emotional connection through online-offline blending,reforming assessment to value process and growth,and empowering teachers as digitally literate“learning guides”and“emotional connectors”are key to building a healthy,sustainable interactive ecosystem.
文摘In the past few decades,China's foreign trade,leveraging its comprehensive industrial system,resilient supply chain,and factor cost advantages,has steadily constructed a global division of labor pattern as the“world's factory”.
文摘BACKGROUND Acinar cystic transformation(ACT)of the pancreas is a rare non-neoplastic transformation of the pancreas.Adult women are the majority of patients with ACT,but few cases have been reported in pediatric patients.Given that there are currently no guidelines for the treatment of ACT,current treatment is based primarily on expert opinions and clinical experiences.Here,we report the case of the youngest child with ACT to date.Additionally,a literature review on pediatric ACT cases was performed to summarize previous clinical experience and treatment methods.CASE SUMMARY A 1-year-old Chinese girl presented with progressive abdominal distension for 6 months.A detailed consultation revealed an uneventful history.The patient showed no signs of fever or abdominal pain and had a good appetite and normal feces.A mass of about 20 cm×10 cm×10 cm in size was detected in the abdomen.Both abdominal ultrasound and computed tomography examination revealed a multilocular cystic mass about 21.7 cm×16.8 cm×8.9 cm in size.At first,due to the large size and the possible retroperitoneal origin of the cyst,a total resection of the lesion was not possible.A single-port laparoscopic lymphangioma puncture and Pingyangmycin injection were performed in March 2023.One month after surgery,the abdominal cyst rapidly enlarged to its pre-operative size.After consulting with the experts in the angiology department and interventional department,sclerotherapy combined with oral sirolimus was performed in May 2023.After confirming that the tumor was not sensitive to sclerotherapy combined with oral sirolimus,our surgical team performed tumor reduction in August 2023.This surgery confirmed that the polycystic mass originated from the head of the pancreas,and pathological and immunohistochemical findings diagnosed pancreatic ACT.The patient showed no signs of cyst lesions after 6 months of follow-up and remains in good health up to the time of this report.CONCLUSION ACT is a rare non-neoplastic transformation of the pancreas,more rarely seen in children.Manifestation and examinations show no specificity for diagnosis,and final diagnosis is mainly based on histological findings.To reach a specific diagnosis and rule out malignancy is a priority in clinical practice,and repeated biopsy or radical surgery should be considered before malignancy is ruled out.However,once a diagnosis of ACT is made,a conser-vative treatment with consecutive follow-up is recommended until symptoms present or obvious enlargement occurs because ACT is considered a slow-growing and benign tumor.
基金funded by the Key-Area Research and Development Program of Guangdong Province(Grant No.2022B0202070002)the Guangxi Science and Technology Major Program(Grant No.GuikeAA23023007-2)+1 种基金the Guangdong Province Modern Agricultural Industry Technology System Innovation Team Construction Project(2024CXTD19)Guangdong Basic and Applied Basic Research Foundation(Grant No.2023A1515010303)。
文摘Agrobacterium tumefaciens-mediated transformation has been widely adopted for plant genetic engineering and the study of gene function(Krenek et al.,2015).This method is prevalent in the genetic transformation of herbaceous plants,with notable applications in species such as Arabidopsis(Yin et al.,2024),soybean(Zhang et al.,2024),rice(Zhang et al.,2020),and Chinese cabbage(Li et al.,2021).However,its application in fruit trees is limited.This is primarily due to their long growth cycles and lack of rapid,efficient,and stable transgenic systems,which severely hinders foundational research involving plant genetic transformation(Mei et al.,2024).Furthermore,for subtropical fruit trees,the presence of recalcitrant seeds adds an extra layer of difficulty to genetic transformation(Umarani et al.,2015),as most methods rely on seed germination as a basis for transformation.
基金financially supported by the National Natural Science Foundation of China(No.52374259)the Open Fund of the State Key Laboratory of Mineral Processing Science and Technology,China(No.BGRIMM-KJSKL-2023-11)the Major Science and Technology Projects in Yunnan Province,China(No.202302 AF080004)。
文摘It is difficult to recover chrysocolla from sulfidation flotation which is closely related to the mineral surface composition.In this study,the effects of fluoride roasting on the surface composition of chrysocolla were investigated,its impact on sulfidation flotation was explored,and the mechanisms involved in both fluoride roasting and sulfidation flotation were discussed.With CaF_(2)as the roasting reagent,Na_(2)S·9H_(2)O as the sulfidation reagent,and sodium butyl xanthate(NaBX)as the collector,the results of the flotation experiments showed that fluoride roasting improved the floatability of chrysocolla,and the recovery rate increased from 16.87%to 82.74%.X-ray diffraction analysis revealed that after fluoride roasting,approximately all the Cu on the chrysocolla surface was exposed in the form of CuO,which could provide a basis for subsequent sulfidation flotation.The microscopy and elemental analyses revealed that large quantities of"pagoda-like"grains were observed on the sulfidation surface of the fluoride-roasted chrysocolla,indicating high crystallinity particles of copper sulfide.This suggests that the effect of sulfide formation on the chrysocolla surface was more pronounced.X-ray photoelectron spectroscopy revealed that fluoride roasting increased the relative contents of sulfur and copper on the surface and that both the Cu~+and polysulfide fractions on the surface of the minerals increased.This enhances the effect of sulfidation,which is conducive to flotation recovery.Therefore,fluoride roasting improved the effect of copper species transformation and sulfidation on the surface of chysocolla,promoted the adsorption of collectors,and improved the recovery of chrysocolla from sulfidation flotation.
基金supported by the National Natural Science Foundation of China(82160727)the Major Science and Technique Programs in Yunnan Province(202304BT090021-ML05)Yunnan Agricultural University research start-up Fund(KY2022-02).
文摘The demand for Erigeron breviscapus,a medicinal Compositae plant with cardiovascular therapeutic properties,has been increasing by 15%annually,exceeding production capacity and necessitating improvements in yield and bioactive compound content.Genetic transformation remains essential for functional genomics,yet current Agrobacterium and biolistic methods are inefficient and expensive.In this study,we cloned the full-length sequences of the BABY BOOM,WUSCHEL and GROWTH-REGULATING FACTOR(GRF)genes of E.breviscapus and then transformed them into E.breviscapus explants.The transformation efficiency for the GRF gene reached 45%,and all the transgenic E.breviscapus plants were fertile without obvious developmental defects.Furthermore,we inserted EbGRF4 and Cas9-EbPDS-sgRNA into the same vector for Agrobacterium-mediated transformation to effectively knock out the PDS gene,resulting in albino seedlings,with a gene editing efficiency of 33.3%.These findings provide a solid foundation for functional genomic research and the genetic improvement of E.breviscapus,as well as an important reference for establishing high-efficiency genetic transformation systems for other medicinal plants.
基金funded by the Key R&D Program of Shandong Province,China (2024LZGC035)the Start-up Foundation for High Talents of Qingdao Agricultural University,China (665/1120012)。
文摘Peanuts(Arachis hypogaea) are important sources of vegetable oil,protein,and forage.The genus Arachis comprises nine intrageneric taxonomic sections encompassing 84 species.Most Arachis species are wild plants that serve widely as forage and turfgrass.Furthermore,wild Arachis species provide valuable gene resources for broadening the genetic diversity of cultivated peanuts.To date,several key genes have been identified through the use of recombinant inbred lines derived from interspecific crosses within Arachis.Despite this progress,the application of genetic engineering to enhance peanut traits remains limited.This limitation arises primarily from the absence of a robust and reliable genetic transformation protocol for Arachis species.Nevertheless,evidence indicates that successful genetic transformation of Arachis plants was first reported approximately 30 years ago.Thus,a notable discrepancy exists between early reports of transformation success and the ongoing challenges in stably transferring candidate genes into Arachis genotypes.This review summarizes existing methods for regeneration and genetic transformation in Arachis,aiming to advance understanding of transgenic technologies applicable to this genus.
基金supported by the National Key Research and Development Program of China(Grant No.2024YFB4504101)the National Nat-ural Science Foundation of China(Grant No.22303022)the Anhui Province Innovation Plan for Science and Technology(Grant No.202423r06050002).
文摘Using a quantum computer to simulate fermionic systems requires fermion-to-qubit transformations.Usually,lower Pauli weight of transformations means shallower quantum circuits.Therefore,most existing transformations aim for lower Pauli weight.However,in some cases,the circuit depth depends not only on the Pauli weight but also on the coefficients of the Hamiltonian terms.In order to characterize the circuit depth of these algorithms,we propose a new metric called weighted Pauli weight,which depends on Pauli weight and coefficients of Hamiltonian terms.To achieve smaller weighted Pauli weight,we introduce a novel transformation,Huffman-code-based ternary tree(HTT)transformation,which is built upon the classical Huffman code and tailored to different Hamiltonians.We tested various molecular Hamiltonians and the results show that the weighted Pauli weight of the HTT transformation is smaller than that of commonly used mappings.At the same time,the HTT transformation also maintains a relatively small Pauli weight.The mapping we designed reduces the circuit depth of certain Hamiltonian simulation algorithms,facilitating faster simulation of fermionic systems.
基金the UGC,New Delhi,India for financial assistance via the UGC-Junior Research Fellowship(CSIR-UGC NET JULY 2024)(Student ID:241610090610)。
文摘The flow of a tetra-hybrid Casson nanofluid(Al_(2)O_(3)-CuO-TiO_(2)-Ag/H_(2)O)over a nonlinear stretching sheet is investigated.The Buongiorno model is used to account for thermophoresis and Brownian motion,while thermal radiation is incorporated to examine its influence on the thermal boundary layer.The governing partial differential equations(PDEs)are reduced to a system of nonlinear ordinary differential equations(ODEs)with fully non-dimensional similarity transformations involving all independent variables.To solve the obtained highly nonlinear system of differential equations,a novel Clique polynomial collocation method is applied.The analysis focuses on the effects of the Casson parameter,power index,radiation parameter,thermophoresis parameter,Brownian motion parameter,and Lewis number.The key findings show that thermal radiation intensifies the thermal boundary layer,the Casson parameter reduces the velocity,and the Lewis number suppresses the concentration with direct relevance to polymer processing,coating flows,electronic cooling,and biomedical applications.
文摘On January 23,2026,the second plenary session of the China Expo Forum for International Cooperation(CEFCO) convened in Wuhan,Hubei Province.Amid significant changes in the global exhibition landscape,participants shared recent developments,key data,and future trends in major markets,offering guidance for industry practitioners to drive progress.
文摘From lecture halls in Beijing to villages in the mountains of southwest China,a group of young rural innovators from Global South countries recently embarked on a journey that connected policy thinking,technological practice and lived rural experience.
文摘With the theme of“standardized approaches empowering industrial green and low-carbon transformation”,a sub-forum was held to promote the application of the carbon footprint management system in China,advance the wide implementation of relevant standards,and accelerate the globalization process of green product trade through high-level communication.Lyu Xuefeng,Director of Qingdao Institute of Bioenergy and Bioprocess Technology(QIBEBT),Chinese Academy of Sciences,emphasized in his address that the product carbon footprint management system is the important support for industrial green transformation.The geographic information system-life cycle assessment(GIS-LCA)technology has been originally proposed and adopted as the core content of the national standard GB/T 24067-2024,Greenhouse gases-Carbon footprint of products-Requirements and guidelines for quantification.
文摘The China Expo Forum for International Cooperation(CEFCO)2026 was held in Wuhan,Hubei Province,China,on January 22.The opening ceremony was attended by Li Qing Shuang,Vice President of the China Council for the Promotion of International Trade(CCPIT);Zhu Yuji,Deputy Secretary of the Hubei Provincial Committee of the Communist Party of China;Sheng Yue Chun,Member of the Standing Committee of the Hubei Provincial Committee of the Communist Party of China and Secretary of the Wuhan Municipal Committee;Punita Bhansal,President of the Global Association of the Exhibition Industry(UFI);Marsha Flanagan,President and CEO of the International Association of Exhibitions and Events(IAEE);Vincent Polito,CEO of the Society of Independent Show Organizers(SISO);and Leonie Ashford,Board Member of the International Congress and Convention Association(ICCA).
文摘As the global economy has been undergoing profound changes and the industrial and supply chains have been restructuring rapidly,China International Supply Chain Expo(hereinafter referred to as the CISCE)emerged with the time.
文摘In-situ tensile tests were conducted on a chemically corroded third-generation single-crystal superalloy DD9 at 980 and 1100℃.The phase transformation in the surface areas during the tensile process was analyzed using field emission scanning electron microscope,energy dispersive X-ray spectroscope,electron probe X-ray microanalysis,and transmission electron microscope.The phase transformation mechanism on the surface and the influence mechanism were studied through observation and dynamic calculation.During tensile tests at elevated temperatures,chemical corrosion promotes the precipitation of topologically close-packed(tcp)μphase andσphase on the alloy surface.Both the precipitation amount and size of these two phases on the surface at 1100℃are greater than those at 980℃.The precipitation of tcp phase on the alloy surface results in the formation of an influence layer on the surface area,and the distribution characteristics of alloying elements are significantly different from those of the substrate.The depth of the influence layer at 1100℃is greater than that at 980℃.The precipitation of tcp phase prompts the phase transition fromγphase toγ′phase around the tcp phase.
文摘The world today is undergoing accelerated transformations unseen in a century.The international environment,fluid and volatile,is evolving in multiple dimensions beyond time and space.Faced with emerging and intensifying global challenges in the security,political,economic,technological and other fields,the international community has a pressing need to reshape the international landscape at this critical moment of change.
基金supported by the National Science and Technology Major Project-Intelligent Manufacturing Systems And Robots(2025ZD1602200)the National Key Research and Development Program of China(Grant No.2022YFB3304800).
文摘The accurate establishment of a ferrite transformation start temperature model is crucial to design a reasonable controlled rolling process and ensure uniform microstructure in aluminum bearing dual-phase steel.The measurements of the expansion-temperature curves of aluminum bearing dual-phase steel under continuous cooling and isothermal conditions are presented,utilizing a dynamic transformation dilatometer experiment.Based on these expansion-temperature curves,the start temperature and incubation time of ferrite transformation were determined,elucidating the influence of process parameters on both the incubation time and the start temperature of ferrite transformation.By integrating metallurgical principles with measured incubation time of ferrite transformation,and considering the effects of temperature and strain,a fitting model for the variation in volume free energy during ferrite nucleation was derived.Building upon this foundation,a high-precision incubation time of ferrite transformation mathematical model for the experimental steel was established.To more accurately calculate the start temperature of ferrite transformation under continuous cooling conditions,the Scheil’s additivity rule was modified to account for the effects of deformation and cooling rate.The results indicate that the modification coefficient decreases with increasing the cooling rate and strain,thereby significantly improving the accuracy of calculating the starting temperature of ferrite transformation using the modified additivity rule.
基金supported by the National University of Defense Technology Research Fund Projectthe National Natural Science Foundation of China(Grant No.12534013)the Science and Technology Innovation Program of Hunan Province(Grant Nos.2025ZYJ001 and 2021RC4026)。
文摘Understanding the complex deformation mechanisms of non-equimolar multi-principal element alloys(MPEAs)requires high-fidelity atomic-scale simulations.This study develops a deep potential(DP)model to enable molecular dynamics simulations of the Ta_(0.4)Ti_(2)Zr(Ta_(0.4))alloy.Monte Carlo simulations using this potential reveal Ta atom precipitation in the Ta_(0.4)alloy.Under uniaxial tensile loading along the[100]direction in the NPT ensemble,the alloy undergoes a remarkable sequence of phase transformations:an initial body-centered cubic(BCC_(1))to face-centered cubic(FCC)transformation,followed by a reverse transformation from FCC to a distinct BCC phase(BCC_(2)),and finally a BCC_(2) to hexagonal close-packed(HCP)transformation.Critically,the reverse FCC to BCC_(2) transformation induces significant volume contraction.We demonstrate that the inversely transformed BCC_(2) phase primarily accommodates compressive stress.Concurrently,the reorientation of BCC_(2) crystals contributes substantially to the observed high strain hardening.These simulations provide atomic-scale insights into the dynamic structural evolution,sequential phase transformations,and stress partitioning during deformation of the Ta_(0.4)alloy.The developed DP model and the revealed mechanisms offer fundamental theoretical guidance for accelerating the design of high-performance MPEAs.
