On the tranquil waters of Xiaoshanyang,a small lake in Deqing County,Zhejiang Province,rows of white,spherical buoys are lined up in perfect order,resembling strands of pearl necklaces.Once a thousand-year-old pearl-f...On the tranquil waters of Xiaoshanyang,a small lake in Deqing County,Zhejiang Province,rows of white,spherical buoys are lined up in perfect order,resembling strands of pearl necklaces.Once a thousand-year-old pearl-farming site,this heritage-rich waterbody has emerged as a global benchmark for the preservation of agricultural heritage.展开更多
When studying the harbor water tranquility, cases are often confronted as that the verification point is not located on the generation line or that the angle between the generation line and the isobath is so large tha...When studying the harbor water tranquility, cases are often confronted as that the verification point is not located on the generation line or that the angle between the generation line and the isobath is so large that the differences of the wave climates along the generation line can not be ignored. For these cases, the incident boundary conditions are difficult to evaluate. In order to solve this problem, a combined wave model is developed in the present paper based on the Boussinesq equation and the wave action balance equation. Instead of the one-line wave generation method, a multi-line generation method is proposed for the combined model. Application of this method is given to a case that the harbor is designed with two entrances and the angle between the generation line and the isobath is large and the results are shown reasonable. We suggest that the wave generation method on multi-lines might also be introduced to the wave physical model as the replacement for the one-line generation method.展开更多
Delirium is the most frequent manifestation of acute brain dysfunction in intensive care unit(ICU).Although antipsychotics are widely used to treat this serious complication,recent evidence has emphasized that these a...Delirium is the most frequent manifestation of acute brain dysfunction in intensive care unit(ICU).Although antipsychotics are widely used to treat this serious complication,recent evidence has emphasized that these agents did not reduce ICU delirium(ICU-D)prevalence and did not improve survival,length of ICU or hospital stay after its occurrence.Of note,no pharmacological strategy to prevent or treat delirium has been identified,so far.In this scenario,new scientific evidences are urgently needed.Investigations on specific ICU-D subgroups,or focused on different clinical settings,and studies on medications other than antipsychotics,such as dexmedetomidine or melatonin,may represent interesting fields of research.In the meantime,because there is some evidence that ICU-D can be effectively prevented,the literature suggests strengthening all the strategies aimed at prevention through no-pharmacological approaches mostly focused on the correction of risk factors.The more appropriate strategy useful to treat established delirium remains the use of antipsychotics managed by choosing the right doses after a careful case-by-case analysis.While the evidence regarding the use of dexmedetomidine is still conflicting and sparse,this drug offers interesting perspectives for both ICU-D prevention and treatment.This paper aims to provide an overview of current pharmacological approaches of evidence-based medicine practice.The state of the art of the on-going clinical research on the topic and perspectives for future research are also addressed.展开更多
Effects of tranquil and its inhalation toxicity in experimental animals were studied. The drug was administered to the mice through respiratory tract by a static intoxication equipment. Automatic activities (AA) of mi...Effects of tranquil and its inhalation toxicity in experimental animals were studied. The drug was administered to the mice through respiratory tract by a static intoxication equipment. Automatic activities (AA) of mice were recorded by a YSD4G pharmacologicalphysiological multitrack recording equipment to evaluate the combined effects of tranquil and pentobarbital. Changes in amount of cerebral 5hydroxytryptamine(5HT) and 5hydroxyindole acetic acid (5HIAA) were observed. The results showed that tranquil could reduce the AA of mice and exert a synergic hypnotic effect with pentobarbital. There was a tendency in decreasing cerebral 5HT and increasing 5HIAA. LC50 value for mice exceeded 70 000 mg/m\+3. In rats exposed to tranquil at 59 066 mg/m\+3, 4 hours every day for 3 consecutive days, Author no respiratory irritative action was observed. This indicated the inhibitory effects of tranquil on the CNS of mice. Its action mechanism is probably different from that of diazepam and may be related to the function of central neurotransmitter 5hydroxytryptamine. Tranquil has low inhalation toxicity and no irritative action on the respiratory tract.\;展开更多
The main oil-bearing formation of Area 4 of Tahe oilfield is in Yingshan Group of Ordovician consisted of thick pure limestone. The types of the pore space contain the pore, fissure, cave as well as fracture formed by...The main oil-bearing formation of Area 4 of Tahe oilfield is in Yingshan Group of Ordovician consisted of thick pure limestone. The types of the pore space contain the pore, fissure, cave as well as fracture formed by solution collapse. The primary porosity and tectonic fracture are of poor growth. Therefore, the formation growth is mainly controlled by hydraulic units of the palaeo-karst. There are three palaeo-hydraulic zones: vadose zone (including infiltration sub-zone and percolation sub-zone), phreatic zone and tranquil zone. They are identified by retrieving the palaeo-geographical karst environment. The pore space of the infiltration zone is mainly solution fissures, small solution cavities and solution pores. The growth and lateral connection of the formation are favorable. The reservoir/formation ratio is 0. 54. The pore space of the phreatic zone developed large size cavities and fractures related to cave collapse. The height of the cavity can reach 71m. The fractures by collapse have a influencing range of more than 100m, and its reservoir/formation ratio is 0. 51. But the lateral connection is unfavorable. The percolation subzone and the tranquil zone are of relatively poor growth with the reservoir/ formation ratio less than 0. 3.展开更多
BEIJING visitors or residents looking to spend down time in a tranquil setting can opt for the Niujie Mosque and its surrounds -a charming and often overlooked part of the capital. Niujie is the name of the street whe...BEIJING visitors or residents looking to spend down time in a tranquil setting can opt for the Niujie Mosque and its surrounds -a charming and often overlooked part of the capital. Niujie is the name of the street where the mosque is located,a name literally meaning Ox Street.The millennium mosque dates back to 996 and is the oldest and at 6,000 square meters,the largest of all the mosques in Beijing.The spacious prayer hall can easily accommodatel,000展开更多
The bustling city in the Himalayas rewards visitors with hidden tranquil gems beyond the normal tourist trail Aweek may sound like a long time to spend visiting one city,but Lhasa,high up on the Himalayan plateau at 3...The bustling city in the Himalayas rewards visitors with hidden tranquil gems beyond the normal tourist trail Aweek may sound like a long time to spend visiting one city,but Lhasa,high up on the Himalayan plateau at 3,656 meters in altitude.展开更多
It was shortly after dusk as I strolled along the riverbank,heading home after a busy working Saturday.The heat of the day was slowly easing,and the riverside park provided an oasis of calm,away from traffic and the b...It was shortly after dusk as I strolled along the riverbank,heading home after a busy working Saturday.The heat of the day was slowly easing,and the riverside park provided an oasis of calm,away from traffic and the bustle of people.The walk was almost meditative.Suddenly;the tranquillity was abruptly interrupted by an electrical screech.Within moments,the air filled with the semi-tuned vocals of an enthusiastic lone singer;whose energy levels obscured his older years.From his loudspeaker;vivid Cantopop beats filled the air;and my peaceful trance was shattered.展开更多
The current study aimed to investigate the quality of the interior architecture of the religious spaces regarding inducing the sense of spirituality with an emphasis on light.Thus,the authors introduced the best optio...The current study aimed to investigate the quality of the interior architecture of the religious spaces regarding inducing the sense of spirituality with an emphasis on light.Thus,the authors introduced the best option by simulating the light intensity of the interior environment of the Nasir Al-Mulk Mosque,Shiraz,in software and developing a visual standard questionnaire with a statistical population including the experts.This research was a field,and survey study and computational software were used to simulate the light intensity of the interior environment of the mosque in the first part.Then,the researcher-made visual questionnaire was developed.Also,this questionnaire was sent to the experts online due to the current situations due to the Covid-19 pandemic.The statistical population was selected using the purposive sampling method from the universities of Iran,Malaysia,India,and Turkey,whose expertise was architecture,environmental psychology,and sacred arts.展开更多
To maintain the calmness of the harbor,rubble mound breakwaters are one of the practical measures to protect sailing and mooring waters.This paper investigates the effect of relocated rubble mound breakwaters on tranq...To maintain the calmness of the harbor,rubble mound breakwaters are one of the practical measures to protect sailing and mooring waters.This paper investigates the effect of relocated rubble mound breakwaters on tranquillity in Busan yacht range and the impact of bridge piers at the entrance of the yacht range based on physical hydraulic modeling using multi-directional random waves.It is obtained that the sufficient tranquillity can be due to securely moored yachts,owing to newly relocated rubble mound breakwaters away from piers.The experimental results also showed the distribution of the energy difference’dependence on various wave directions.The experimental findings are valuable for the design of Busan yacht marina,and are of reference to other port projects.展开更多
文摘On the tranquil waters of Xiaoshanyang,a small lake in Deqing County,Zhejiang Province,rows of white,spherical buoys are lined up in perfect order,resembling strands of pearl necklaces.Once a thousand-year-old pearl-farming site,this heritage-rich waterbody has emerged as a global benchmark for the preservation of agricultural heritage.
基金supported by the National Natural Science Foundation of China(Grant No.50921001)
文摘When studying the harbor water tranquility, cases are often confronted as that the verification point is not located on the generation line or that the angle between the generation line and the isobath is so large that the differences of the wave climates along the generation line can not be ignored. For these cases, the incident boundary conditions are difficult to evaluate. In order to solve this problem, a combined wave model is developed in the present paper based on the Boussinesq equation and the wave action balance equation. Instead of the one-line wave generation method, a multi-line generation method is proposed for the combined model. Application of this method is given to a case that the harbor is designed with two entrances and the angle between the generation line and the isobath is large and the results are shown reasonable. We suggest that the wave generation method on multi-lines might also be introduced to the wave physical model as the replacement for the one-line generation method.
文摘Delirium is the most frequent manifestation of acute brain dysfunction in intensive care unit(ICU).Although antipsychotics are widely used to treat this serious complication,recent evidence has emphasized that these agents did not reduce ICU delirium(ICU-D)prevalence and did not improve survival,length of ICU or hospital stay after its occurrence.Of note,no pharmacological strategy to prevent or treat delirium has been identified,so far.In this scenario,new scientific evidences are urgently needed.Investigations on specific ICU-D subgroups,or focused on different clinical settings,and studies on medications other than antipsychotics,such as dexmedetomidine or melatonin,may represent interesting fields of research.In the meantime,because there is some evidence that ICU-D can be effectively prevented,the literature suggests strengthening all the strategies aimed at prevention through no-pharmacological approaches mostly focused on the correction of risk factors.The more appropriate strategy useful to treat established delirium remains the use of antipsychotics managed by choosing the right doses after a careful case-by-case analysis.While the evidence regarding the use of dexmedetomidine is still conflicting and sparse,this drug offers interesting perspectives for both ICU-D prevention and treatment.This paper aims to provide an overview of current pharmacological approaches of evidence-based medicine practice.The state of the art of the on-going clinical research on the topic and perspectives for future research are also addressed.
文摘Effects of tranquil and its inhalation toxicity in experimental animals were studied. The drug was administered to the mice through respiratory tract by a static intoxication equipment. Automatic activities (AA) of mice were recorded by a YSD4G pharmacologicalphysiological multitrack recording equipment to evaluate the combined effects of tranquil and pentobarbital. Changes in amount of cerebral 5hydroxytryptamine(5HT) and 5hydroxyindole acetic acid (5HIAA) were observed. The results showed that tranquil could reduce the AA of mice and exert a synergic hypnotic effect with pentobarbital. There was a tendency in decreasing cerebral 5HT and increasing 5HIAA. LC50 value for mice exceeded 70 000 mg/m\+3. In rats exposed to tranquil at 59 066 mg/m\+3, 4 hours every day for 3 consecutive days, Author no respiratory irritative action was observed. This indicated the inhibitory effects of tranquil on the CNS of mice. Its action mechanism is probably different from that of diazepam and may be related to the function of central neurotransmitter 5hydroxytryptamine. Tranquil has low inhalation toxicity and no irritative action on the respiratory tract.\;
文摘The main oil-bearing formation of Area 4 of Tahe oilfield is in Yingshan Group of Ordovician consisted of thick pure limestone. The types of the pore space contain the pore, fissure, cave as well as fracture formed by solution collapse. The primary porosity and tectonic fracture are of poor growth. Therefore, the formation growth is mainly controlled by hydraulic units of the palaeo-karst. There are three palaeo-hydraulic zones: vadose zone (including infiltration sub-zone and percolation sub-zone), phreatic zone and tranquil zone. They are identified by retrieving the palaeo-geographical karst environment. The pore space of the infiltration zone is mainly solution fissures, small solution cavities and solution pores. The growth and lateral connection of the formation are favorable. The reservoir/formation ratio is 0. 54. The pore space of the phreatic zone developed large size cavities and fractures related to cave collapse. The height of the cavity can reach 71m. The fractures by collapse have a influencing range of more than 100m, and its reservoir/formation ratio is 0. 51. But the lateral connection is unfavorable. The percolation subzone and the tranquil zone are of relatively poor growth with the reservoir/ formation ratio less than 0. 3.
文摘BEIJING visitors or residents looking to spend down time in a tranquil setting can opt for the Niujie Mosque and its surrounds -a charming and often overlooked part of the capital. Niujie is the name of the street where the mosque is located,a name literally meaning Ox Street.The millennium mosque dates back to 996 and is the oldest and at 6,000 square meters,the largest of all the mosques in Beijing.The spacious prayer hall can easily accommodatel,000
文摘The bustling city in the Himalayas rewards visitors with hidden tranquil gems beyond the normal tourist trail Aweek may sound like a long time to spend visiting one city,but Lhasa,high up on the Himalayan plateau at 3,656 meters in altitude.
文摘It was shortly after dusk as I strolled along the riverbank,heading home after a busy working Saturday.The heat of the day was slowly easing,and the riverside park provided an oasis of calm,away from traffic and the bustle of people.The walk was almost meditative.Suddenly;the tranquillity was abruptly interrupted by an electrical screech.Within moments,the air filled with the semi-tuned vocals of an enthusiastic lone singer;whose energy levels obscured his older years.From his loudspeaker;vivid Cantopop beats filled the air;and my peaceful trance was shattered.
基金This paper is sponsored by the University of Florence,Italy.
文摘The current study aimed to investigate the quality of the interior architecture of the religious spaces regarding inducing the sense of spirituality with an emphasis on light.Thus,the authors introduced the best option by simulating the light intensity of the interior environment of the Nasir Al-Mulk Mosque,Shiraz,in software and developing a visual standard questionnaire with a statistical population including the experts.This research was a field,and survey study and computational software were used to simulate the light intensity of the interior environment of the mosque in the first part.Then,the researcher-made visual questionnaire was developed.Also,this questionnaire was sent to the experts online due to the current situations due to the Covid-19 pandemic.The statistical population was selected using the purposive sampling method from the universities of Iran,Malaysia,India,and Turkey,whose expertise was architecture,environmental psychology,and sacred arts.
基金supported for two years by Pusan National University Research Grant BK21 PLUS.
文摘To maintain the calmness of the harbor,rubble mound breakwaters are one of the practical measures to protect sailing and mooring waters.This paper investigates the effect of relocated rubble mound breakwaters on tranquillity in Busan yacht range and the impact of bridge piers at the entrance of the yacht range based on physical hydraulic modeling using multi-directional random waves.It is obtained that the sufficient tranquillity can be due to securely moored yachts,owing to newly relocated rubble mound breakwaters away from piers.The experimental results also showed the distribution of the energy difference’dependence on various wave directions.The experimental findings are valuable for the design of Busan yacht marina,and are of reference to other port projects.
