To deploy sensor nodes over the area of interest,a scheme,named node scattering manipulation,was proposed.It adopted the following method:during node scattering,the initial states of every node,including the velocity ...To deploy sensor nodes over the area of interest,a scheme,named node scattering manipulation,was proposed.It adopted the following method:during node scattering,the initial states of every node,including the velocity and direction,were manipulated so that it would land in a region with a certain probability;every sensor was relocated in order to improve the coverage and connectivity.Simultaneously,to easily analyze the process of scattering sensors,a trajectory model was also proposed.Integrating node scattering manipulation with trajectory model,the node deployment in wireless sensor network was thoroughly renovated,that is,this scheme can scatter sensors.In practice,the scheme was operable compared with the previous achievements.The simulation results demonstrate the superiority and feasibility of the scheme,and also show that the energy consumption for sensors relocation is reduced.展开更多
In this study,it is aimed to develop a generic model which calculates the trajectory of the ejection seat from the jet aircraft,by taking into account the parameters that will affect the seat movement such as the seat...In this study,it is aimed to develop a generic model which calculates the trajectory of the ejection seat from the jet aircraft,by taking into account the parameters that will affect the seat movement such as the seat’s launch speed,ejection direction,ejection angle,altitude of the aircraft,distance/height from the aircraft rudder and canopy,pilot and ejection seat weight.With the model algorithm proposed,the ejection seat trajectory model was developed on MATLAB.The ejection seat trajectory model is based on point mass trajectory mathematical model.In this study,an analytical study of the problem has been made for modeling the flight trajectory of the ejection seat after it has been ejected.Past studies were used as a basis for validation and simulation.By writing a generic MATLAB code,a user interface was developed and presented to the user as a module.This generic code that has been developed could be used for simulations by users in the future by revising it in accordance with their own job descriptions.展开更多
To accurately reconstruct the tomographic gamma scanning(TGS)transmission measurement image,this study optimized the transmission reconstruction equation based on the actual situation of TGS transmission measurement.U...To accurately reconstruct the tomographic gamma scanning(TGS)transmission measurement image,this study optimized the transmission reconstruction equation based on the actual situation of TGS transmission measurement.Using the transmission reconstruction equation and the Monte Carlo program Geant4,an innovative virtual trajectory length model was constructed.This model integrated the solving process for the trajectory length and detection efficiency within the same model.To mitigate the influence of the angular distribution ofγ-rays emitted by the transmitted source at the detector,the transport processes of numerous particles traversing a virtual nuclear waste barrel with a density of zero were simulated.Consequently,a certain amount of information was captured at each step of particle transport.Simultaneously,the model addressed the nonuniform detection efficiency of the detector end face by considering whether the energy deposition of particles in the detector equaled their initial energy.Two models were established to validate the accuracy and reliability of the virtual trajectory length model.Model 1 was a simplified nuclear waste barrel,whereas Model 2 closely resembled the actual structure of a nuclear waste barrel.The results indicated that the proposed virtual trajectory length model significantly enhanced the precision of the trajectory length determination,substantially increasing the quality of the reconstructed images.For example,the reconstructed images of Model 2 using the“point-to-point”and average trajectory models revealed a signalto-noise ratio increase of 375.0%and 112.7%,respectively.Thus,the virtual trajectory length model proposed in this study holds paramount significance for the precise reconstruction of transmission images.Moreover,it can provide support for the accurate detection of radioactive activity in nuclear waste barrels.展开更多
BACKGROUND Neck pain,a primary symptom of cervical spondylosis,affects patients'physical and mental health,reducing their quality of life.Pain and emotional state interact;however,their longitudinal interrelations...BACKGROUND Neck pain,a primary symptom of cervical spondylosis,affects patients'physical and mental health,reducing their quality of life.Pain and emotional state interact;however,their longitudinal interrelationship remains unclear.In this study,we applied a dual-trajectory model to assess how neck pain and emotional state evolve together over time and how clinical interventions,particularly acupuncture,influence these trajectories.AIM To investigate the longitudinal relationship between neck pain and emotional state in patients with cervical spondylosis.METHODS This prospective cohort study included 472 patients with cervical spondylosis from eight Chinese hospitals.Participants received acupuncture or medication and were followed up at baseline,and at 1,2,4,6,and 8 weeks.Neck pain and emotional distress were assessed using the Northwick Park Neck Pain Questionnaire(NPQ)and the affective subscale of the Short-Form McGill Pain Questionnaire(SF-MPQ),respectively.Group-based trajectory models and dual trajectory analysis were used to identify and correlate pain-emotion trajectories.Multivariate logistic regression identified predictors of group membership.RESULTS Three trajectory groups were identified for NPQ and SF-MPQ scores(low,medium,and high).Higher NPQ trajectory was associated with older age(OR=1.058,P<0.001)and was significantly reduced by acupuncture(OR=0.382,P<0.001).Similarly,acupuncture lowered the odds of high SF-MPQ trajectory membership(OR=0.336,P<0.001),while age increased it(OR=1.037,P<0.001).Dual-trajectory analysis revealed bidirectional associations:69.1%of patients with low NPQ had low SF-MPQ scores,and 42.6%of patients with high SF-MPQ also had high NPQ scores.Gender was a predictor for medium SF-MPQ trajectory(OR=1.629,P=0.094).Occupation and education levels differed significantly across the trajectory groups(P<0.05).CONCLUSION Over time,neck pain and emotional distress are closely associated in patients with cervical spondylosis.Acupuncture alleviates both outcomes significantly,while age is a risk factor.Integrated approaches to pain and emotional management are encouraged.展开更多
Objective We aimed to investigate the patterns of fasting blood glucose(FBG)trajectories and analyze the relationship between various occupational hazard factors and FBG trajectories in male steelworkers.Methods The s...Objective We aimed to investigate the patterns of fasting blood glucose(FBG)trajectories and analyze the relationship between various occupational hazard factors and FBG trajectories in male steelworkers.Methods The study cohort included 3,728 workers who met the selection criteria for the Tanggang Occupational Cohort(TGOC)between 2017 and 2022.A group-based trajectory model was used to identify the FBG trajectories.Environmental risk scores(ERS)were constructed using regression coefficients from the occupational hazard model as weights.Univariate and multivariate logistic regression analyses were performed to explore the effects of occupational hazard factors using the ERS on FBG trajectories.Results FBG trajectories were categorized into three groups.An association was observed between high temperature,noise exposure,and FBG trajectory(P<0.05).Using the first quartile group of ERS1 as a reference,the fourth quartile group of ERS1 had an increased risk of medium and high FBG by 1.90and 2.21 times,respectively(odds ratio[OR]=1.90,95%confidence interval[CI]:1.17–3.10;OR=2.21,95%CI:1.09–4.45).Conclusion An association was observed between occupational hazards based on ERS and FBG trajectories.The risk of FBG trajectory levels increase with an increase in ERS.展开更多
A huge amount of sensitive personal data is being collected by various online health monitoring applications.Although the data is anonymous,the personal trajectories(e.g.,the chronological access records of small cell...A huge amount of sensitive personal data is being collected by various online health monitoring applications.Although the data is anonymous,the personal trajectories(e.g.,the chronological access records of small cells)could become the anchor of linkage attacks to re-identify the users.Focusing on trajectory privacy in online health monitoring,we propose the User Trajectory Model(UTM),a generic trajectory re-identification risk predicting model to reveal the underlying relationship between trajectory uniqueness and aggregated data(e.g.,number of individuals covered by each small cell),and using the parameter combination of aggregated data to further mathematically derive the statistical characteristics of uniqueness(i.e.,the expectation and the variance).Eventually,exhaustive simulations validate the effectiveness of the UTM in privacy risk evaluation,confirm our theoretical deductions and present counter-intuitive insights.展开更多
Background:To identify the distinct trajectories of the Sequential Organ Failure Assessment(SOFA)scores at 72 h for patients with sepsis in the Medical Information Mart for Intensive Care(MIMIC)-IV database and determ...Background:To identify the distinct trajectories of the Sequential Organ Failure Assessment(SOFA)scores at 72 h for patients with sepsis in the Medical Information Mart for Intensive Care(MIMIC)-IV database and determine their effects on mortality and adverse clinical outcomes.Methods:A retrospective cohort study was carried out involving patients with sepsis from the MIMIC-IV database.Group-based trajectory modeling(GBTM)was used to identify the distinct trajectory groups for the SOFA scores in patients with sepsis in the intensive care unit(ICU).The Cox proportional hazards regression model was used to investigate the relationship between the longitudinal change trajectory of the SOFA score and mortality and adverse clinical outcomes.Results:A total of 16,743 patients with sepsis were included in the cohort.The median survival age was 66 years(interquartile range:54-76 years).The 7-day and 28-day in-hospital mortality were 6.0%and 17.6%,respectively.Five different trajectories of SOFA scores according to the model fitting standard were determined:group 1(32.8%),group 2(30.0%),group 3(17.6%),group 4(14.0%)and group 5(5.7%).Univariate and multivariate Cox regression analyses showed that,for different clinical outcomes,trajectory group 1 was used as the reference,while trajectory groups 2-5 were all risk factors associated with the outcome(P<0.001).Subgroup analysis revealed an interaction between the two covariates of age and mechanical ventilation and the different trajectory groups of patients’SOFA scores(P<0.05).Conclusion:This approach may help identify various groups of patients with sepsis,who may be at different levels of risk for adverse health outcomes,and provide subgroups with clinical importance.展开更多
After pointed the unreasonableness of the three basic assumptions contained in HMM, we introduce the theory and the advantage of Stochastic najectory Models (STMs) that possibly resolve these problems caused by HMM as...After pointed the unreasonableness of the three basic assumptions contained in HMM, we introduce the theory and the advantage of Stochastic najectory Models (STMs) that possibly resolve these problems caused by HMM assumptions. In STM, the acoustic observations of an acoustic unit are represented as clusters of trajectories in a parameter space.The trajectories are modelled by mixture of probability density functions of random sequence of states. After analyzing the characteristics of Chinese speech, the acoustic units for continuous Chinese speech recognition based on STM are discussed and phone-like units are suggested. The performance of continuous Chinese speech recognition based on STM is studied on VINICS system. The experimental results prove the efficiency of STM and the consistency of phone-like units.展开更多
[ Objective] The research aimed to study application of the trajectory plume model in atmospheric environmental impact assessment. [ Method] Trajectory plume model was used to retrospectively evaluate regional atmosph...[ Objective] The research aimed to study application of the trajectory plume model in atmospheric environmental impact assessment. [ Method] Trajectory plume model was used to retrospectively evaluate regional atmospheric improvement degree by fuel gas desulfurization project in Mawan Power Plant of Shenzhen. On this basis, we analyzed applicability of the model in atmospheric prediction of the construction project. [- Re- sult~ Under the situation of complex flow field and variable weather condition, the trajectory plume model displayed good prediction accuracy, to- gether with the use of flow field diagnosis model. Under complex weather condition, this model could be complementary to atmospheric environmen- tal quality prediction model recommended by new atmosphere guidelines, which had the value of popularization in future atmospheric environmental evaluation and planning. [ Conduslon~ Trajectory plume model had broad application potential in atmospheric environmental impact assessment.展开更多
A multi-lattice deterministic trajectory(MLDT) model is developed to simulate dense gas-particle flow in a vertical channel.The actual inter-particle collision and particle motion are treated by a Lagrangian model wit...A multi-lattice deterministic trajectory(MLDT) model is developed to simulate dense gas-particle flow in a vertical channel.The actual inter-particle collision and particle motion are treated by a Lagrangian model with three sets of lattices to reduce computational time.Cluster formation and motion near the wall are successfully predicted with mean particle volume fraction and velocity,showing quantitatively agreement with experimental results.The mechanism of particles concentrated near the wall is investigated by considering effects of gravity,particle-wall collisions,inter-particle collisions and velocity profiles of the gas phase.It is shown that the inter-particle collision and gas-phase velocity distribution are the essential factors for cluster formation near the wall,while gravity and particle-wall collision only have minor effects on particle concentration near the wall.Particles are unable to remain in the high velocity region due to the strong inter-particle collisions,while they tend to stay in the low velocity region for weak inter-particle collisions.In addition,the effects of channel width and particle sizes on cluster formation are also investigated and it is found that particle concentration near the wall reduces with the decrease of channel width and increase of particle size.展开更多
Airports are being developed and expanded rapidly in China to accommodate and promote a growing aviation market.The future Beijing Daxing International Airport（DAX） will serve as the central airport of the JingJinJi...Airports are being developed and expanded rapidly in China to accommodate and promote a growing aviation market.The future Beijing Daxing International Airport（DAX） will serve as the central airport of the JingJinJi megaregion,knitting the Beijing,Tianjin,and Hebei regions together.DAX will be a busy airport from its inception,relieving congestion and accommodating growth from Beijing Capital International Airport（PEK）,currently the second busiest airport in the world in passengers moved.We aim to model terminal airspace designs and possible conflicts in the future Beijing Multi-Airport System（MAS）.We investigate standard arrival procedures and mathematically model current and future arrival trajectories into PEK and DAX by collecting large quantities of publicly available track data from historical arrivals operating within the Beijing terminal airspace.We find that（1） trajectory models constructed from real data capture aberrations and deviations from standard arrival procedures,validating the need to incorporate data on historical trajectories with standard procedures when evaluating the airspace and（2） given all existing constraints,DAX may be restricted to using north and east arrival flows,constraining the capacity required to handle the increases in air traffic demand to Beijing.The results indicate that the terminal airspace above Beijing,and the future JingJinJi region,requires careful consideration if the full capacity benefits of the two major airports are to be realized.展开更多
It is essential to learn the temporal and spatial concentration distributions and variations of seeding agents in cloud seeding of precipitation enhancement. A three-dimensional puff trajectory model incorporating a m...It is essential to learn the temporal and spatial concentration distributions and variations of seeding agents in cloud seeding of precipitation enhancement. A three-dimensional puff trajectory model incorporating a mesoscale nonhydrostatic model has been formulated, and is applied to simulating the transporting and diffusive characteristics of multiple line sources of seeding agents within super-cooled stratus. Several important factors are taken into consideration that affect the diffusion of seeding materials such as effects of topography and vertical wind shear, temporal and spatial variation of seeding parameters and wet deposition. The particles of seeding agents are assumed to be almost inert, they have no interaction with the particles of the cloud or precipitation except that they are washed out by precipitation. The model validity is demonstrated by the analyses and comparisons of model results, and checked by the sensitivity experiments of diffusive coefficients and atmospheric stratification. The advantage of this model includes not only its exact reflection of heterogeneity and unsteadiness of background fields, but also its good simulation of transport and diffusion of multiple line sources. The horizontal diffusion rate and the horizontal transport distance have been proposed that they usually were difficult to obtain in other models. In this simulation the horizontal diffusion rate is 0.82 m s(-1) for average of one hour, and the horizontal average transport distance reaches 65 km after 1 4 which are closely related to the background Fields.展开更多
Intersections are quite important and complex traffic scenarios,where the future motion of surrounding vehicles is an indispensable reference factor for the decision-making or path planning of autonomous vehicles.Cons...Intersections are quite important and complex traffic scenarios,where the future motion of surrounding vehicles is an indispensable reference factor for the decision-making or path planning of autonomous vehicles.Considering that the motion trajectory of a vehicle at an intersection partly obeys the statistical law of historical data once its driving intention is determined,this paper proposes a long short-term memory based(LSTM-based)framework that combines intention prediction and trajectory prediction together.First,we build an intersection prior trajectories model(IPTM)by clustering and statistically analyzing a large number of prior traffic flow trajectories.The prior trajectories model with fitted probabilistic density is used to approximate the distribution of the predicted trajectory,and also serves as a reference for credibility evaluation.Second,we conduct the intention prediction through another LSTM model and regard it as a crucial cue for a trajectory forecast at the early stage.Furthermore,the predicted intention is also a key that is associated with the prior trajectories model.The proposed framework is validated on two publically released datasets,next generation simulation(NGSIM)and INTERACTION.Compared with other prediction methods,our framework is able to sample a trajectory from the estimated distribution,with its accuracy improved by about 20%.Finally,the credibility evaluation,which is based on the prior trajectories model,makes the framework more practical in the real-world applications.展开更多
In this paper, we construct two models for the searching task for a lost plane. Model 1 determines the searching area. We predict the trajectory of floats generated after the disintegration of the plane by using RBF n...In this paper, we construct two models for the searching task for a lost plane. Model 1 determines the searching area. We predict the trajectory of floats generated after the disintegration of the plane by using RBF neural network model, and then determine the searching area according to the trajectory. With the pass of time, the searching area will also be constantly moving along the trajectory. Model 2 develops a maritime search plan to achieve the purpose of completing the search in the shortest time. We optimize the searching time and transform the problem into the 0-1 knapsack problem. Solving this problem by improved genetic algorithm, we can get the shortest searching time and the best choice for the search power.展开更多
Objective To explore the impact of baseline remnant cholesterol levels at a single time point and cumulative remnant cholesterol exposure on the progression trajectories of arterial stiffness.Methods This prospective ...Objective To explore the impact of baseline remnant cholesterol levels at a single time point and cumulative remnant cholesterol exposure on the progression trajectories of arterial stiffness.Methods This prospective cohort study included 2401 eligible participants from the Beijing Health Management Cohort who consecutively attended health examinations in 2010-2011,2012-2013,and 2014-2015.The remnant cholesterol value measured in 2014-2015 served as the baseline remnant cholesterol level at a single time point.The cumulative exposure indices were calculated based on remnant cholesterol values from three health examinations from 2010 to 2015,including cumulative exposure,cumulative exposure burden,and duration of high remnant cholesterol exposure.Arterial stiffness was assessed by brachialankle pulse wave velocity(baPWV).The follow-up continued until December 31,2019,with annual checkups.During the follow-up period,a group-based trajectory model was employed to construct the progression trajectories of baPWV.The associations between the baseline remnant cholesterol level,cumulative exposure indices of remnant cholesterolandbaPWV trajectories were examined using ordinal logisticcregression models,adjusting for traditional cardiovascular risk factors and low-density lipoprotein cholesterol(LDL-C)levels.Results The age of the 2401 participants was 61(54,69)years,with 1801(75.01%)being male.The group-based trajectory model indicated that the best-fit model categorized the participants into three subgroups:low-rising group(1036 individuals,43.15%),moderaterising group(1137 individuals,47.36%),and highrising group(228 individuals,9.50%).After adjusting for traditional cardiovascular risk factors,baseline remnant cholesterol levels at a single point(OR=1.170,95%Cl:1.074-1.274),cumulative remnant cholesterol exposure(0R=1.194,95%Cl:1.096-1.303),cumulative remnant cholesterol exposure burden(OR=1.270,95%CI:1.071-1.507),and high-remnant cholesterol exposure duration(6 years:OR=1.351,95%Cl:1.077-1.695)were significantly associated with the risk of developing a poor baPWV progression trajectory.TTheseresults remainedsignificanttafter adjusting for cumulative average LDL-C levels.The association between baseline remnant cholesterol levels and baPWV progression became insignificant after adjusting for cumulative remnant cholesterol levels(OR=1.053,95%CI:0.923-1.197),while the association between cumulative remnant cholesterol exposure and baPWV progression remained significant after adjusting for baseline remnant cholesterol levels(OR=1.145,95%CI:1.008-1.305).Conclusion Higher levels of baseline remnant cholesterol and cumulative remnant cholesterol are independent risk factors forthe progression of arterial stiffness.Theseassociations remain significant even after adjusting for traditional cardiovascularrisk factorsandLDL-Clevels.Furthermore,the effect of cumulative remnant cholesterol levels on the progression of arterial stiffness is stronger than the effect of baseline remnant cholesterol levels.展开更多
Characterization of the spatial and temporal variability of stable isotopes in surface water is essential for interpreting hydrological processes.In this study,we collected the water samples of river water,groundwater...Characterization of the spatial and temporal variability of stable isotopes in surface water is essential for interpreting hydrological processes.In this study,we collected the water samples of river water,groundwater,and reservoir water in the Burqin River Basin of the Altay Mountains,China in 2021,and characterized the oxygen and hydrogen isotope variations in different water bodies via instrumental analytics and modeling.Results showed significant seasonal variations in stable isotope ratios of oxygen and hydrogen(δ18O andδ2H,respectively)and significant differences inδ18O andδ2H among different water bodies.Higherδ18O andδ2H values were mainly found in river water,while groundwater and reservoir water had lower isotope ratios.River water and groundwater showed differentδ18O-δ2H relationships with the local meteoric water line,implying that river water and groundwater are controlled by evaporative enrichment and multi-source recharge processes.The evaporative enrichment experienced by reservoir water was less significant and largely influenced by topography,recharge sources,local moisture cycling,and anthropogenic factors.Higher deuterium excess(d-excess)value of 14.34‰for river water probably represented the isotopic signature of combined contributions from direct precipitation,snow and glacial meltwater,and groundwater recharge.The average annual d-excess values of groundwater(10.60‰)and reservoir water(11.49‰)were similar to the value of global precipitation(10.00‰).The findings contribute to understanding the hydroclimatic information reflected in the month-by-month variations in stable isotopes in different water bodies and provide a reference for the study of hydrological processes and climate change in the Altay Mountains,China.展开更多
Recycled moisture is an important indicator of the renewal capacity of regional water resources.Due to the existence of Yulong Snow Mountain,Lijiang in Yunnan Province,southeast of the Qinghai-Tibet Plateau,China,is t...Recycled moisture is an important indicator of the renewal capacity of regional water resources.Due to the existence of Yulong Snow Mountain,Lijiang in Yunnan Province,southeast of the Qinghai-Tibet Plateau,China,is the closest ocean glacier area to the equator in Eurasia.Daily precipitation samples were collected from 2017 to 2018 in Lijiang to quantify the effect of sub-cloud evaporation and recycled moisture on precipitation combined with the d-excess model during monsoon and non-monsoon periods.The results indicated that the d-excess values of precipitation fluctuated between–35.6‰and 16.0‰,with an arithmetic mean of 3.5‰.The local meteoric water line(LMWL)wasδD=7.91δ^(18)O+2.50,with a slope slightly lower than the global meteoric water line(GMWL).Subcloud evaporation was higher during the non-monsoon season than during the monsoon season.It tended to peak in March and was primarily influenced by the relative humidity.The source of the water vapour affected the proportion of recycled moisture.According to the results of the Hybrid Single-Particle Lagrangian Integrated Trajectory(HYSPLIT)model,the main sources of water vapour in Lijiang area during the monsoon period were the southwest and southeast monsoons.During the non-monsoon period,water vapour was transported by a southwesterly flow.The recycled moisture in Lijiang area between March and October 2017 was 10.62%.Large variations were observed between the monsoon and non-monsoon seasons,with values of 5.48%and 25.65%,respectively.These differences were primarily attributed to variations in the advection of water vapour.The recycled moisture has played a supplementary role in the precipitation of Lijiang area.展开更多
Erosion-corrosion of liquid-solid two-phase flow occurring in a pipe with sudden expansion in cross-section is numerically simulated in this paper. The global model for erosion-corrosion process includes three main co...Erosion-corrosion of liquid-solid two-phase flow occurring in a pipe with sudden expansion in cross-section is numerically simulated in this paper. The global model for erosion-corrosion process includes three main components: the liquid-solid two-phase flow model, erosion model and corrosion model. The Eulerian-Lagrangian approach is used to simulate liquid-solid two-phase flow, while the stochastic trajectory model was adopted to obtain properties of particle phase. Two-way coupling effect between the fluid and the particle phase is considered in the model. The accuracy of the models is tested by the data in the reference. The comparison shows that the model is basically correct and feasible.展开更多
Background:Septic shock has a high incidence and mortality rate in Intensive Care Units(ICUs).Earlier intravenous fluid resuscitation can significantly improve outcomes in septic patients but easily leads to fluid ove...Background:Septic shock has a high incidence and mortality rate in Intensive Care Units(ICUs).Earlier intravenous fluid resuscitation can significantly improve outcomes in septic patients but easily leads to fluid overload(FO),which is associated with poor clinical outcomes.A single point value of fluid cannot provide enough fluid information.The aim of this study was to investigate the impact of fluid balance(FB)latent trajectories on clinical outcomes in septic patients.Methods:Patients were diagnosed with septic shock during the first 48 h,and sequential fluid data for the first 3 days of ICU admission were included.A group-based trajectory model(GBTM)which is designed to identify groups of individuals following similar developmental trajectories was used to identify latent subgroups of individuals following a similar progression of FB.The primary outcomes were hospital mortality,organ dysfunction,major adverse kidney events(MAKE)and severe respiratory adverse events(SRAE).We used multivariable Cox or logistic regression analysis to assess the association between FB trajectories and clinical outcomes.Results:Nine hundred eighty-six patients met the inclusion criteria and were assigned to GBTM analysis,and three latent FB trajectories were detected.64(6.5%),841(85.3%),and 81(8.2%)patients were identified to have decreased,low,and high FB,respectively.Compared with low FB,high FB was associated with increased hospital mortality[hazard ratio(HR)=1.63,95%CI 1.22–2.17],organ dysfunction[odds ratio(OR)=2.18,95%CI 1.22–3.42],MAKE(OR=1.80,95%CI 1.04–2.63)and SRAE(OR=2.33,95%CI 1.46–3.71),and decreasing FB was significantly associated with decreased MAKE(OR=0.46,95%CI 0.29–0.79)after adjustment for potential covariates.Conclusion:Latent subgroups of septic patients followed a similar FB progression.These latent fluid trajectories were associated with clinical outcomes.The decreasing FB trajectory was associated with a decreased risk of hospital mortality and MAKE.展开更多
The intraseasonal oscillation(ISO) of the South China Sea(SCS, 105-120°E, 5-20°N) convection and its influences on the genesis and track of the western North Pacific(WNP) tropical cyclones(TCs) were explored...The intraseasonal oscillation(ISO) of the South China Sea(SCS, 105-120°E, 5-20°N) convection and its influences on the genesis and track of the western North Pacific(WNP) tropical cyclones(TCs) were explored, based on the daily average of NCEP/NCAR reanalysis data, the OLR data and the western North Pacific tropical cyclone best-track data from 1979 to 2008. The mechanism of the influences of ISO on TC movement and the corresponding large-scale circulation were discussed by a trajectory model. It was found as follows.(1) During the SCS summer monsoon, the SCS convection exhibits the ISO features with active phases alternating with inactive phases. The monsoon circulation patterns are significantly different during these two phases. When the SCS convection is active(inactive), the SCS-WNP monsoon trough stretches eastward(retreats westward) due to the activity(inactivity) of SCS monsoon, and the WNP subtropical high retreats eastward(stretches westward), which enhances(suppresses) the monsoon circulation.(2) The amount of TC genesis in the active phase is much more than that in the inactive phase. A majority of TCs form west of 135 °E during the active phases but east of 135 °E in the inactive phases.(3) The TCs entering the area west of 135 °E and south of 25 °N would move straight into the SCS in the active phase, or recurve northward in the inactive phase.(4) Simulation results show that the steering flow associated with the active(inactive)phases is in favor of straight-moving(recurving) TCs. Meanwhile, the impacts of the locations of TC genesis on the characteristics of TC track cannot be ignored. TCs that occurred father westward are more likely to move straight into the SCS region.展开更多
基金Project(2007AA01Z224) supported by National High-Tech Research and Development Program of China
文摘To deploy sensor nodes over the area of interest,a scheme,named node scattering manipulation,was proposed.It adopted the following method:during node scattering,the initial states of every node,including the velocity and direction,were manipulated so that it would land in a region with a certain probability;every sensor was relocated in order to improve the coverage and connectivity.Simultaneously,to easily analyze the process of scattering sensors,a trajectory model was also proposed.Integrating node scattering manipulation with trajectory model,the node deployment in wireless sensor network was thoroughly renovated,that is,this scheme can scatter sensors.In practice,the scheme was operable compared with the previous achievements.The simulation results demonstrate the superiority and feasibility of the scheme,and also show that the energy consumption for sensors relocation is reduced.
文摘In this study,it is aimed to develop a generic model which calculates the trajectory of the ejection seat from the jet aircraft,by taking into account the parameters that will affect the seat movement such as the seat’s launch speed,ejection direction,ejection angle,altitude of the aircraft,distance/height from the aircraft rudder and canopy,pilot and ejection seat weight.With the model algorithm proposed,the ejection seat trajectory model was developed on MATLAB.The ejection seat trajectory model is based on point mass trajectory mathematical model.In this study,an analytical study of the problem has been made for modeling the flight trajectory of the ejection seat after it has been ejected.Past studies were used as a basis for validation and simulation.By writing a generic MATLAB code,a user interface was developed and presented to the user as a module.This generic code that has been developed could be used for simulations by users in the future by revising it in accordance with their own job descriptions.
基金supported by The Youth Science Foundation of Sichuan Province(Nos.2022NSFSC1230,2022NSFSC1231,and 23NSFSC5321)the Science and Technology Innovation Seedling Project of Sichuan Province(No.MZGC20230080)+2 种基金the General project of national Natural Science Foundation of China(No.12075039)the Youth Science Foundation of China(No.12105030)the Key project of the National Natural Science Foundation of China(No.U19A2086)。
文摘To accurately reconstruct the tomographic gamma scanning(TGS)transmission measurement image,this study optimized the transmission reconstruction equation based on the actual situation of TGS transmission measurement.Using the transmission reconstruction equation and the Monte Carlo program Geant4,an innovative virtual trajectory length model was constructed.This model integrated the solving process for the trajectory length and detection efficiency within the same model.To mitigate the influence of the angular distribution ofγ-rays emitted by the transmitted source at the detector,the transport processes of numerous particles traversing a virtual nuclear waste barrel with a density of zero were simulated.Consequently,a certain amount of information was captured at each step of particle transport.Simultaneously,the model addressed the nonuniform detection efficiency of the detector end face by considering whether the energy deposition of particles in the detector equaled their initial energy.Two models were established to validate the accuracy and reliability of the virtual trajectory length model.Model 1 was a simplified nuclear waste barrel,whereas Model 2 closely resembled the actual structure of a nuclear waste barrel.The results indicated that the proposed virtual trajectory length model significantly enhanced the precision of the trajectory length determination,substantially increasing the quality of the reconstructed images.For example,the reconstructed images of Model 2 using the“point-to-point”and average trajectory models revealed a signalto-noise ratio increase of 375.0%and 112.7%,respectively.Thus,the virtual trajectory length model proposed in this study holds paramount significance for the precise reconstruction of transmission images.Moreover,it can provide support for the accurate detection of radioactive activity in nuclear waste barrels.
基金Supported by 2022 Chinese Medicine Scientific Research Project of Hebei Administration of Traditional Chinese Medicine,No.20221572025 Annual Scientific Research Project of Higher Education Institutions in Hebei Province,No.QN2025654.
文摘BACKGROUND Neck pain,a primary symptom of cervical spondylosis,affects patients'physical and mental health,reducing their quality of life.Pain and emotional state interact;however,their longitudinal interrelationship remains unclear.In this study,we applied a dual-trajectory model to assess how neck pain and emotional state evolve together over time and how clinical interventions,particularly acupuncture,influence these trajectories.AIM To investigate the longitudinal relationship between neck pain and emotional state in patients with cervical spondylosis.METHODS This prospective cohort study included 472 patients with cervical spondylosis from eight Chinese hospitals.Participants received acupuncture or medication and were followed up at baseline,and at 1,2,4,6,and 8 weeks.Neck pain and emotional distress were assessed using the Northwick Park Neck Pain Questionnaire(NPQ)and the affective subscale of the Short-Form McGill Pain Questionnaire(SF-MPQ),respectively.Group-based trajectory models and dual trajectory analysis were used to identify and correlate pain-emotion trajectories.Multivariate logistic regression identified predictors of group membership.RESULTS Three trajectory groups were identified for NPQ and SF-MPQ scores(low,medium,and high).Higher NPQ trajectory was associated with older age(OR=1.058,P<0.001)and was significantly reduced by acupuncture(OR=0.382,P<0.001).Similarly,acupuncture lowered the odds of high SF-MPQ trajectory membership(OR=0.336,P<0.001),while age increased it(OR=1.037,P<0.001).Dual-trajectory analysis revealed bidirectional associations:69.1%of patients with low NPQ had low SF-MPQ scores,and 42.6%of patients with high SF-MPQ also had high NPQ scores.Gender was a predictor for medium SF-MPQ trajectory(OR=1.629,P=0.094).Occupation and education levels differed significantly across the trajectory groups(P<0.05).CONCLUSION Over time,neck pain and emotional distress are closely associated in patients with cervical spondylosis.Acupuncture alleviates both outcomes significantly,while age is a risk factor.Integrated approaches to pain and emotional management are encouraged.
基金supported by the Key Research and Development Program of the Ministry of Science and Technology of China(grant number:2016YF0900605)the Key Research and Development Program of Hebei Province(grant number:192777129D)+1 种基金the Joint Fund for Iron and Steel of the Natural Science Foundation of Hebei Province(grant number:H2016209058)the National Natural Science Foundation for Regional Joint Fund of China(grant number:U22A20364)。
文摘Objective We aimed to investigate the patterns of fasting blood glucose(FBG)trajectories and analyze the relationship between various occupational hazard factors and FBG trajectories in male steelworkers.Methods The study cohort included 3,728 workers who met the selection criteria for the Tanggang Occupational Cohort(TGOC)between 2017 and 2022.A group-based trajectory model was used to identify the FBG trajectories.Environmental risk scores(ERS)were constructed using regression coefficients from the occupational hazard model as weights.Univariate and multivariate logistic regression analyses were performed to explore the effects of occupational hazard factors using the ERS on FBG trajectories.Results FBG trajectories were categorized into three groups.An association was observed between high temperature,noise exposure,and FBG trajectory(P<0.05).Using the first quartile group of ERS1 as a reference,the fourth quartile group of ERS1 had an increased risk of medium and high FBG by 1.90and 2.21 times,respectively(odds ratio[OR]=1.90,95%confidence interval[CI]:1.17–3.10;OR=2.21,95%CI:1.09–4.45).Conclusion An association was observed between occupational hazards based on ERS and FBG trajectories.The risk of FBG trajectory levels increase with an increase in ERS.
基金This work was supported in part by the National Natural Science Foundation of China under Grant 61871062and Grant 61771082the Natural Science Foundation of Chongqing of China under Grant cstc2013jcyjA40066+3 种基金the Program for Innovation Team Building at Institutions of Higher Education in Chongqing under Grant CXTDX201601020the Science and Technology Research Program of Chongqing Municipal Education Commission under Grant KJQN201801316the Key Industrial Technology Development Project of Chongqing of China Development and Reform Commission under Grant 2018148208the Innovation and Entrepreneurship Demonstration Team of Yingcai Program of Chongqing of China under Grant CQYC201903167.
文摘A huge amount of sensitive personal data is being collected by various online health monitoring applications.Although the data is anonymous,the personal trajectories(e.g.,the chronological access records of small cells)could become the anchor of linkage attacks to re-identify the users.Focusing on trajectory privacy in online health monitoring,we propose the User Trajectory Model(UTM),a generic trajectory re-identification risk predicting model to reveal the underlying relationship between trajectory uniqueness and aggregated data(e.g.,number of individuals covered by each small cell),and using the parameter combination of aggregated data to further mathematically derive the statistical characteristics of uniqueness(i.e.,the expectation and the variance).Eventually,exhaustive simulations validate the effectiveness of the UTM in privacy risk evaluation,confirm our theoretical deductions and present counter-intuitive insights.
文摘Background:To identify the distinct trajectories of the Sequential Organ Failure Assessment(SOFA)scores at 72 h for patients with sepsis in the Medical Information Mart for Intensive Care(MIMIC)-IV database and determine their effects on mortality and adverse clinical outcomes.Methods:A retrospective cohort study was carried out involving patients with sepsis from the MIMIC-IV database.Group-based trajectory modeling(GBTM)was used to identify the distinct trajectory groups for the SOFA scores in patients with sepsis in the intensive care unit(ICU).The Cox proportional hazards regression model was used to investigate the relationship between the longitudinal change trajectory of the SOFA score and mortality and adverse clinical outcomes.Results:A total of 16,743 patients with sepsis were included in the cohort.The median survival age was 66 years(interquartile range:54-76 years).The 7-day and 28-day in-hospital mortality were 6.0%and 17.6%,respectively.Five different trajectories of SOFA scores according to the model fitting standard were determined:group 1(32.8%),group 2(30.0%),group 3(17.6%),group 4(14.0%)and group 5(5.7%).Univariate and multivariate Cox regression analyses showed that,for different clinical outcomes,trajectory group 1 was used as the reference,while trajectory groups 2-5 were all risk factors associated with the outcome(P<0.001).Subgroup analysis revealed an interaction between the two covariates of age and mechanical ventilation and the different trajectory groups of patients’SOFA scores(P<0.05).Conclusion:This approach may help identify various groups of patients with sepsis,who may be at different levels of risk for adverse health outcomes,and provide subgroups with clinical importance.
文摘After pointed the unreasonableness of the three basic assumptions contained in HMM, we introduce the theory and the advantage of Stochastic najectory Models (STMs) that possibly resolve these problems caused by HMM assumptions. In STM, the acoustic observations of an acoustic unit are represented as clusters of trajectories in a parameter space.The trajectories are modelled by mixture of probability density functions of random sequence of states. After analyzing the characteristics of Chinese speech, the acoustic units for continuous Chinese speech recognition based on STM are discussed and phone-like units are suggested. The performance of continuous Chinese speech recognition based on STM is studied on VINICS system. The experimental results prove the efficiency of STM and the consistency of phone-like units.
文摘[ Objective] The research aimed to study application of the trajectory plume model in atmospheric environmental impact assessment. [ Method] Trajectory plume model was used to retrospectively evaluate regional atmospheric improvement degree by fuel gas desulfurization project in Mawan Power Plant of Shenzhen. On this basis, we analyzed applicability of the model in atmospheric prediction of the construction project. [- Re- sult~ Under the situation of complex flow field and variable weather condition, the trajectory plume model displayed good prediction accuracy, to- gether with the use of flow field diagnosis model. Under complex weather condition, this model could be complementary to atmospheric environmen- tal quality prediction model recommended by new atmosphere guidelines, which had the value of popularization in future atmospheric environmental evaluation and planning. [ Conduslon~ Trajectory plume model had broad application potential in atmospheric environmental impact assessment.
基金partially supported by the National Basic Research Program of China ("973" Project) (Grant No. 62980532)
文摘A multi-lattice deterministic trajectory(MLDT) model is developed to simulate dense gas-particle flow in a vertical channel.The actual inter-particle collision and particle motion are treated by a Lagrangian model with three sets of lattices to reduce computational time.Cluster formation and motion near the wall are successfully predicted with mean particle volume fraction and velocity,showing quantitatively agreement with experimental results.The mechanism of particles concentrated near the wall is investigated by considering effects of gravity,particle-wall collisions,inter-particle collisions and velocity profiles of the gas phase.It is shown that the inter-particle collision and gas-phase velocity distribution are the essential factors for cluster formation near the wall,while gravity and particle-wall collision only have minor effects on particle concentration near the wall.Particles are unable to remain in the high velocity region due to the strong inter-particle collisions,while they tend to stay in the low velocity region for weak inter-particle collisions.In addition,the effects of channel width and particle sizes on cluster formation are also investigated and it is found that particle concentration near the wall reduces with the decrease of channel width and increase of particle size.
文摘Airports are being developed and expanded rapidly in China to accommodate and promote a growing aviation market.The future Beijing Daxing International Airport（DAX） will serve as the central airport of the JingJinJi megaregion,knitting the Beijing,Tianjin,and Hebei regions together.DAX will be a busy airport from its inception,relieving congestion and accommodating growth from Beijing Capital International Airport（PEK）,currently the second busiest airport in the world in passengers moved.We aim to model terminal airspace designs and possible conflicts in the future Beijing Multi-Airport System（MAS）.We investigate standard arrival procedures and mathematically model current and future arrival trajectories into PEK and DAX by collecting large quantities of publicly available track data from historical arrivals operating within the Beijing terminal airspace.We find that（1） trajectory models constructed from real data capture aberrations and deviations from standard arrival procedures,validating the need to incorporate data on historical trajectories with standard procedures when evaluating the airspace and（2） given all existing constraints,DAX may be restricted to using north and east arrival flows,constraining the capacity required to handle the increases in air traffic demand to Beijing.The results indicate that the terminal airspace above Beijing,and the future JingJinJi region,requires careful consideration if the full capacity benefits of the two major airports are to be realized.
文摘It is essential to learn the temporal and spatial concentration distributions and variations of seeding agents in cloud seeding of precipitation enhancement. A three-dimensional puff trajectory model incorporating a mesoscale nonhydrostatic model has been formulated, and is applied to simulating the transporting and diffusive characteristics of multiple line sources of seeding agents within super-cooled stratus. Several important factors are taken into consideration that affect the diffusion of seeding materials such as effects of topography and vertical wind shear, temporal and spatial variation of seeding parameters and wet deposition. The particles of seeding agents are assumed to be almost inert, they have no interaction with the particles of the cloud or precipitation except that they are washed out by precipitation. The model validity is demonstrated by the analyses and comparisons of model results, and checked by the sensitivity experiments of diffusive coefficients and atmospheric stratification. The advantage of this model includes not only its exact reflection of heterogeneity and unsteadiness of background fields, but also its good simulation of transport and diffusion of multiple line sources. The horizontal diffusion rate and the horizontal transport distance have been proposed that they usually were difficult to obtain in other models. In this simulation the horizontal diffusion rate is 0.82 m s(-1) for average of one hour, and the horizontal average transport distance reaches 65 km after 1 4 which are closely related to the background Fields.
基金partly supported by the National Natural Science Foundation of China(61903034,U1913203,61973034,91120003)the Program for Changjiang Scholars and Innovative Research Team in University(IRT-16R06,T2014224)+1 种基金China Postdoctoral Science Foundation funded project(2019TQ0035)Beijing Institute of Technology Research Fund Program for Young Scholars。
文摘Intersections are quite important and complex traffic scenarios,where the future motion of surrounding vehicles is an indispensable reference factor for the decision-making or path planning of autonomous vehicles.Considering that the motion trajectory of a vehicle at an intersection partly obeys the statistical law of historical data once its driving intention is determined,this paper proposes a long short-term memory based(LSTM-based)framework that combines intention prediction and trajectory prediction together.First,we build an intersection prior trajectories model(IPTM)by clustering and statistically analyzing a large number of prior traffic flow trajectories.The prior trajectories model with fitted probabilistic density is used to approximate the distribution of the predicted trajectory,and also serves as a reference for credibility evaluation.Second,we conduct the intention prediction through another LSTM model and regard it as a crucial cue for a trajectory forecast at the early stage.Furthermore,the predicted intention is also a key that is associated with the prior trajectories model.The proposed framework is validated on two publically released datasets,next generation simulation(NGSIM)and INTERACTION.Compared with other prediction methods,our framework is able to sample a trajectory from the estimated distribution,with its accuracy improved by about 20%.Finally,the credibility evaluation,which is based on the prior trajectories model,makes the framework more practical in the real-world applications.
文摘In this paper, we construct two models for the searching task for a lost plane. Model 1 determines the searching area. We predict the trajectory of floats generated after the disintegration of the plane by using RBF neural network model, and then determine the searching area according to the trajectory. With the pass of time, the searching area will also be constantly moving along the trajectory. Model 2 develops a maritime search plan to achieve the purpose of completing the search in the shortest time. We optimize the searching time and transform the problem into the 0-1 knapsack problem. Solving this problem by improved genetic algorithm, we can get the shortest searching time and the best choice for the search power.
文摘Objective To explore the impact of baseline remnant cholesterol levels at a single time point and cumulative remnant cholesterol exposure on the progression trajectories of arterial stiffness.Methods This prospective cohort study included 2401 eligible participants from the Beijing Health Management Cohort who consecutively attended health examinations in 2010-2011,2012-2013,and 2014-2015.The remnant cholesterol value measured in 2014-2015 served as the baseline remnant cholesterol level at a single time point.The cumulative exposure indices were calculated based on remnant cholesterol values from three health examinations from 2010 to 2015,including cumulative exposure,cumulative exposure burden,and duration of high remnant cholesterol exposure.Arterial stiffness was assessed by brachialankle pulse wave velocity(baPWV).The follow-up continued until December 31,2019,with annual checkups.During the follow-up period,a group-based trajectory model was employed to construct the progression trajectories of baPWV.The associations between the baseline remnant cholesterol level,cumulative exposure indices of remnant cholesterolandbaPWV trajectories were examined using ordinal logisticcregression models,adjusting for traditional cardiovascular risk factors and low-density lipoprotein cholesterol(LDL-C)levels.Results The age of the 2401 participants was 61(54,69)years,with 1801(75.01%)being male.The group-based trajectory model indicated that the best-fit model categorized the participants into three subgroups:low-rising group(1036 individuals,43.15%),moderaterising group(1137 individuals,47.36%),and highrising group(228 individuals,9.50%).After adjusting for traditional cardiovascular risk factors,baseline remnant cholesterol levels at a single point(OR=1.170,95%Cl:1.074-1.274),cumulative remnant cholesterol exposure(0R=1.194,95%Cl:1.096-1.303),cumulative remnant cholesterol exposure burden(OR=1.270,95%CI:1.071-1.507),and high-remnant cholesterol exposure duration(6 years:OR=1.351,95%Cl:1.077-1.695)were significantly associated with the risk of developing a poor baPWV progression trajectory.TTheseresults remainedsignificanttafter adjusting for cumulative average LDL-C levels.The association between baseline remnant cholesterol levels and baPWV progression became insignificant after adjusting for cumulative remnant cholesterol levels(OR=1.053,95%CI:0.923-1.197),while the association between cumulative remnant cholesterol exposure and baPWV progression remained significant after adjusting for baseline remnant cholesterol levels(OR=1.145,95%CI:1.008-1.305).Conclusion Higher levels of baseline remnant cholesterol and cumulative remnant cholesterol are independent risk factors forthe progression of arterial stiffness.Theseassociations remain significant even after adjusting for traditional cardiovascularrisk factorsandLDL-Clevels.Furthermore,the effect of cumulative remnant cholesterol levels on the progression of arterial stiffness is stronger than the effect of baseline remnant cholesterol levels.
基金This work was funded by the Science and Technology Program of Gansu Province(23ZDFA017,22ZD6FA005)the Third Xinjiang Scientific Expedition Program(2022xjkk0802).
文摘Characterization of the spatial and temporal variability of stable isotopes in surface water is essential for interpreting hydrological processes.In this study,we collected the water samples of river water,groundwater,and reservoir water in the Burqin River Basin of the Altay Mountains,China in 2021,and characterized the oxygen and hydrogen isotope variations in different water bodies via instrumental analytics and modeling.Results showed significant seasonal variations in stable isotope ratios of oxygen and hydrogen(δ18O andδ2H,respectively)and significant differences inδ18O andδ2H among different water bodies.Higherδ18O andδ2H values were mainly found in river water,while groundwater and reservoir water had lower isotope ratios.River water and groundwater showed differentδ18O-δ2H relationships with the local meteoric water line,implying that river water and groundwater are controlled by evaporative enrichment and multi-source recharge processes.The evaporative enrichment experienced by reservoir water was less significant and largely influenced by topography,recharge sources,local moisture cycling,and anthropogenic factors.Higher deuterium excess(d-excess)value of 14.34‰for river water probably represented the isotopic signature of combined contributions from direct precipitation,snow and glacial meltwater,and groundwater recharge.The average annual d-excess values of groundwater(10.60‰)and reservoir water(11.49‰)were similar to the value of global precipitation(10.00‰).The findings contribute to understanding the hydroclimatic information reflected in the month-by-month variations in stable isotopes in different water bodies and provide a reference for the study of hydrological processes and climate change in the Altay Mountains,China.
基金Under the auspices of National Natural Science Foundation of China(No.42101044,42077188,52109007)。
文摘Recycled moisture is an important indicator of the renewal capacity of regional water resources.Due to the existence of Yulong Snow Mountain,Lijiang in Yunnan Province,southeast of the Qinghai-Tibet Plateau,China,is the closest ocean glacier area to the equator in Eurasia.Daily precipitation samples were collected from 2017 to 2018 in Lijiang to quantify the effect of sub-cloud evaporation and recycled moisture on precipitation combined with the d-excess model during monsoon and non-monsoon periods.The results indicated that the d-excess values of precipitation fluctuated between–35.6‰and 16.0‰,with an arithmetic mean of 3.5‰.The local meteoric water line(LMWL)wasδD=7.91δ^(18)O+2.50,with a slope slightly lower than the global meteoric water line(GMWL).Subcloud evaporation was higher during the non-monsoon season than during the monsoon season.It tended to peak in March and was primarily influenced by the relative humidity.The source of the water vapour affected the proportion of recycled moisture.According to the results of the Hybrid Single-Particle Lagrangian Integrated Trajectory(HYSPLIT)model,the main sources of water vapour in Lijiang area during the monsoon period were the southwest and southeast monsoons.During the non-monsoon period,water vapour was transported by a southwesterly flow.The recycled moisture in Lijiang area between March and October 2017 was 10.62%.Large variations were observed between the monsoon and non-monsoon seasons,with values of 5.48%and 25.65%,respectively.These differences were primarily attributed to variations in the advection of water vapour.The recycled moisture has played a supplementary role in the precipitation of Lijiang area.
基金Supported by the National Natural Science Foundation of China(N.59831030).
文摘Erosion-corrosion of liquid-solid two-phase flow occurring in a pipe with sudden expansion in cross-section is numerically simulated in this paper. The global model for erosion-corrosion process includes three main components: the liquid-solid two-phase flow model, erosion model and corrosion model. The Eulerian-Lagrangian approach is used to simulate liquid-solid two-phase flow, while the stochastic trajectory model was adopted to obtain properties of particle phase. Two-way coupling effect between the fluid and the particle phase is considered in the model. The accuracy of the models is tested by the data in the reference. The comparison shows that the model is basically correct and feasible.
基金supported by the National Science and Technology Supporting Plan of the Ministry of Science and Technology of China(2012BAI11B05)。
文摘Background:Septic shock has a high incidence and mortality rate in Intensive Care Units(ICUs).Earlier intravenous fluid resuscitation can significantly improve outcomes in septic patients but easily leads to fluid overload(FO),which is associated with poor clinical outcomes.A single point value of fluid cannot provide enough fluid information.The aim of this study was to investigate the impact of fluid balance(FB)latent trajectories on clinical outcomes in septic patients.Methods:Patients were diagnosed with septic shock during the first 48 h,and sequential fluid data for the first 3 days of ICU admission were included.A group-based trajectory model(GBTM)which is designed to identify groups of individuals following similar developmental trajectories was used to identify latent subgroups of individuals following a similar progression of FB.The primary outcomes were hospital mortality,organ dysfunction,major adverse kidney events(MAKE)and severe respiratory adverse events(SRAE).We used multivariable Cox or logistic regression analysis to assess the association between FB trajectories and clinical outcomes.Results:Nine hundred eighty-six patients met the inclusion criteria and were assigned to GBTM analysis,and three latent FB trajectories were detected.64(6.5%),841(85.3%),and 81(8.2%)patients were identified to have decreased,low,and high FB,respectively.Compared with low FB,high FB was associated with increased hospital mortality[hazard ratio(HR)=1.63,95%CI 1.22–2.17],organ dysfunction[odds ratio(OR)=2.18,95%CI 1.22–3.42],MAKE(OR=1.80,95%CI 1.04–2.63)and SRAE(OR=2.33,95%CI 1.46–3.71),and decreasing FB was significantly associated with decreased MAKE(OR=0.46,95%CI 0.29–0.79)after adjustment for potential covariates.Conclusion:Latent subgroups of septic patients followed a similar FB progression.These latent fluid trajectories were associated with clinical outcomes.The decreasing FB trajectory was associated with a decreased risk of hospital mortality and MAKE.
基金National Basic Research Program of China(2015CB953904)National Natural Science Foundation of China(41575081)+1 种基金Startup Foundation for Introducing Talent of NUIST(2015r035)Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)
文摘The intraseasonal oscillation(ISO) of the South China Sea(SCS, 105-120°E, 5-20°N) convection and its influences on the genesis and track of the western North Pacific(WNP) tropical cyclones(TCs) were explored, based on the daily average of NCEP/NCAR reanalysis data, the OLR data and the western North Pacific tropical cyclone best-track data from 1979 to 2008. The mechanism of the influences of ISO on TC movement and the corresponding large-scale circulation were discussed by a trajectory model. It was found as follows.(1) During the SCS summer monsoon, the SCS convection exhibits the ISO features with active phases alternating with inactive phases. The monsoon circulation patterns are significantly different during these two phases. When the SCS convection is active(inactive), the SCS-WNP monsoon trough stretches eastward(retreats westward) due to the activity(inactivity) of SCS monsoon, and the WNP subtropical high retreats eastward(stretches westward), which enhances(suppresses) the monsoon circulation.(2) The amount of TC genesis in the active phase is much more than that in the inactive phase. A majority of TCs form west of 135 °E during the active phases but east of 135 °E in the inactive phases.(3) The TCs entering the area west of 135 °E and south of 25 °N would move straight into the SCS in the active phase, or recurve northward in the inactive phase.(4) Simulation results show that the steering flow associated with the active(inactive)phases is in favor of straight-moving(recurving) TCs. Meanwhile, the impacts of the locations of TC genesis on the characteristics of TC track cannot be ignored. TCs that occurred father westward are more likely to move straight into the SCS region.
