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A Latency-Aware and Fault-Tolerant Framework for Resource Scheduling and Data Management in Fog-Enabled Smart City Transportation Systems
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作者 Ibrar Afzal Noor ul Amin +1 位作者 Zulfiqar Ahmad Abdulmohsen Algarni 《Computers, Materials & Continua》 SCIE EI 2025年第1期1377-1399,共23页
Thedeployment of the Internet of Things(IoT)with smart sensors has facilitated the emergence of fog computing as an important technology for delivering services to smart environments such as campuses,smart cities,and ... Thedeployment of the Internet of Things(IoT)with smart sensors has facilitated the emergence of fog computing as an important technology for delivering services to smart environments such as campuses,smart cities,and smart transportation systems.Fog computing tackles a range of challenges,including processing,storage,bandwidth,latency,and reliability,by locally distributing secure information through end nodes.Consisting of endpoints,fog nodes,and back-end cloud infrastructure,it provides advanced capabilities beyond traditional cloud computing.In smart environments,particularly within smart city transportation systems,the abundance of devices and nodes poses significant challenges related to power consumption and system reliability.To address the challenges of latency,energy consumption,and fault tolerance in these environments,this paper proposes a latency-aware,faulttolerant framework for resource scheduling and data management,referred to as the FORD framework,for smart cities in fog environments.This framework is designed to meet the demands of time-sensitive applications,such as those in smart transportation systems.The FORD framework incorporates latency-aware resource scheduling to optimize task execution in smart city environments,leveraging resources from both fog and cloud environments.Through simulation-based executions,tasks are allocated to the nearest available nodes with minimum latency.In the event of execution failure,a fault-tolerantmechanism is employed to ensure the successful completion of tasks.Upon successful execution,data is efficiently stored in the cloud data center,ensuring data integrity and reliability within the smart city ecosystem. 展开更多
关键词 Fog computing smart cities smart transportation data management fault tolerance resource scheduling
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Black phosphorus nanodots-modified Pt/C electrocatalyst for methanol-tolerant oxygen reduction in direct methanol fuel cells
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作者 Li-Li Zhang Pan-Pan Lu +6 位作者 Ming-Ming Yin Ruo-Nan Li Bing Wang Xian-Di Ma Meng-Gai Jiao Wei Ma Zhen Zhou 《Rare Metals》 2025年第3期1767-1776,共10页
Designing advanced electrocatalysts with high methanol tolerance in the oxygen reduction reaction process is crucial for the sustainable implementation of direct methanol fuel cells.Herein,we present a Pt/C catalyst m... Designing advanced electrocatalysts with high methanol tolerance in the oxygen reduction reaction process is crucial for the sustainable implementation of direct methanol fuel cells.Herein,we present a Pt/C catalyst modified with black phosphorus(BP)nanodots(BPNDs-Pt/C)by using a facile ultrasonic mixing method.Experimental and computational investigations reveal that the electron transfer from BP to Pt leads to weak adsorption of hydroxyl groups on the Pt surface.As a result,the BPNDs-Pt/C catalyst exhibits efficient activity and anti-methanol ability for cathodic oxygen reduction electrocatalysis in an acidic medium.Additionally,it demonstrates high activity for oxygen reduction reaction(ORR)in an alternative alkaline system with cation exchange membrane and eliminable methanol penetration.This work highlights the feasibility of using non-metallic elements to regulate the electronic structure and surface properties of Pt-based nanomaterials.Furthermore,the designed BPNDs-Pt/C electrocatalyst,with controllable ORR performance,can be applied across various scenarios based on demand. 展开更多
关键词 Electrocatalysis Oxygen reduction reaction Methanol tolerant Platinum Black phosphorus
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Data-Driven Fault-Tolerant Bipartite Consensus Tracking for Multi-Agent Systems With a Non-Autonomous Leader
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作者 Yan Zhou Guanghui Wen +1 位作者 Jialing Zhou Tao Yang 《IEEE/CAA Journal of Automatica Sinica》 2025年第1期279-281,共3页
Dear Editor,This letter studies the bipartite consensus tracking problem for heterogeneous multi-agent systems with actuator faults and a leader's unknown time-varying control input. To handle such a problem, the ... Dear Editor,This letter studies the bipartite consensus tracking problem for heterogeneous multi-agent systems with actuator faults and a leader's unknown time-varying control input. To handle such a problem, the continuous fault-tolerant control protocol via observer design is developed. In addition, it is strictly proved that the multi-agent system driven by the designed controllers can still achieve bipartite consensus tracking after faults occur. 展开更多
关键词 fault tolerant actuator faults multi agent systems bipartite consensus tracking data driven bipartite consensus non autonomous leader observer design
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Pentago SnW:An Improved Spray and Wait Protocol for Delay Tolerant Wireless Sensor Networks
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作者 Idris Afzal Shah Mushtaq Ahmed Raghavendra Singh 《China Communications》 2025年第3期104-114,共11页
Delay tolerant wireless sensor networks(DTWSN)is a class of wireless network that finds its deployment in those application scenarios which demand for high packet delivery ratio while maintaining minimal overhead in o... Delay tolerant wireless sensor networks(DTWSN)is a class of wireless network that finds its deployment in those application scenarios which demand for high packet delivery ratio while maintaining minimal overhead in order to prolong network lifetime;owing to resource-constrained nature of sensors.The fundamental requirement of any network is routing a packet from its source to destination.Performance of a routing algorithm depends on the number of network parameters utilized by that routing protocol.In the recent years,various routing protocol has been developed for the delay tolerant networks(DTN).A routing protocol known as spray and wait(SnW)is one of the most widely used routing algorithms for DTN.In this paper,we study the SnW routing protocol and propose a modified version of it referred to as Pentago SnW which is based on pentagonal number series.Comparison to binary SnW shows promising results through simulation using real-life scenarios of cars and pedestrians randomly moving on a map. 展开更多
关键词 binary SnW delay tolerant network Pentago SnW spray and wait routing
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Morpho-Physiological Indices for Identification of Heat Tolerant Wheat Genotypes(Triticum aestivum L.)at Seedling Stage
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作者 S.Y.Labonno M.S.Raihan +1 位作者 M.Mohi-Ud-Din A.K.M.Aminul Islam 《Phyton-International Journal of Experimental Botany》 2025年第5期1545-1563,共19页
Morpho-physiological evaluation of a crop’s genetic resources is necessary to find possible genotypes to include in breeding initiatives.The objective of this study was to identify heat-tolerant wheat genotypes among... Morpho-physiological evaluation of a crop’s genetic resources is necessary to find possible genotypes to include in breeding initiatives.The objective of this study was to identify heat-tolerant wheat genotypes among 36 mutant lines using morpho-physiological indices.Seedlings of mutant lines and check varieties were grown under both normal(control)and heat-stress conditions in growth chambers.Data were recorded on root-shoot parameters(length,fresh weight,dry weight,and ratio),relative water content(RWC),stability of cell membrane,pigment content,and chlorophyll fluorescence.Two-way analysis of variance showed significant(p<0.01,p<0.001)variation among 15 morpho-physiological features in both growing conditions.Correlation studies showed that pigment-specific indices(total chl,chl a,chl b,carotenoid,Fv/Fm—chlorophyll fluorescence)had significant positive correlations with rootshoot fresh weight(RFW,SFW)and root-shoot dry weight(RDW,SDW),and negative association with relative water content,stability of cell membrane at both conditions.Hierarchical cluster analysis revealed three primary clusters where cluster III(18 genotypes)showed minimal changes in studied characters than cluster I(11 genotypes)and cluster II(13 genotypes).Results obtained from this study revealed that the identified heat-sensitive(30-2 SSH)and heat-tolerant genotypes(27-2(4),29-2(2),and 30-2 SSH)of wheat might provide useful breeding materials for enhancing wheat yield even more in this period of uncertain climate change. 展开更多
关键词 Wheat RWC CTD CMS physiological indicators heat tolerance
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Cryogenic 3D printing of damage tolerant hierarchical porous ceramics
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作者 Zheng Zhu Dandan Gao +9 位作者 Zhuo Huang Wei Chang Bin Wu Kaihao Zhang Minghan Sun Hengxu Song Robert O Ritchie Tao Wang Wei Huang Huamin Zhou 《International Journal of Extreme Manufacturing》 2025年第4期265-275,共11页
Fabricating damage tolerant porous ceramics with efficient energy absorption and impact-resistant capability has been a challenge because of the brittle nature of ceramic materials.In nature,mineralized tissues or org... Fabricating damage tolerant porous ceramics with efficient energy absorption and impact-resistant capability has been a challenge because of the brittle nature of ceramic materials.In nature,mineralized tissues or organisms such as cuttlebones and diatoms have evolved with hierarchical porous structures to overcome this difficulty.A bioinspired design of ceramic lattice structure with pores at multiple length scales,ranging from few nanometers to hundreds of micrometers,is proposed in the present work.These ceramic lattices with hierarchical porous structures were successfully fabricated via 3D cryogenic printing.Under quasi-static compressions,the printed ceramic lattices showed unprecedented long plateau strain(∼60%)and a specific energy absorption of∼10 kJ·kg^(−1) with a porosity of∼90%.The resulting energy absorption capability was comparable with most composites and metals,thus overcoming the brittle nature of traditional porous ceramics.This was attributed to the delayed destruction of the lattice structure,as well as the gradual collapse of pores at multiple length scales.Similar trends have also been observed under split Hopkinson pressure bar(SHPB)tests,indicating excellent energy absorption under high strain-rate impacts.The proposed 3D printing technique that produces hierarchical pores was also demonstrated to apply to other functional materials,such as silicon carbide,barium titanate,hydroxyapatite,and even titanium alloy,thus opening up new possibilities for fabricating bioinspired hierarchical porous structures. 展开更多
关键词 hierarchical structure bioinspired designs energy absorption damage tolerance 3D printing
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High-temperature-tolerant flexible supercapacitors: Gel polymer electrolytes and electrode materials
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作者 Chong Peng Xinyi Huang +4 位作者 Mingwei Zhao Shuling Liao Quanhong Yang Nianjun Yang Siyu Yu 《Journal of Energy Chemistry》 2025年第1期426-457,共32页
The development of flexible supercapacitors(FSCs) capable of operating at high temperatures is crucial for expanding the application areas and operating conditions of supercapacitors. Gel polymer electrolytes and elec... The development of flexible supercapacitors(FSCs) capable of operating at high temperatures is crucial for expanding the application areas and operating conditions of supercapacitors. Gel polymer electrolytes and electrode materials stand as two key components that significantly impact the efficacy of hightemperature-tolerant FSCs(HT-FSCs). They should not only exhibit high electrochemical performance and excellent flexibility, but also withstand intense thermal stress. Considerable efforts have been devoted to enhancing their thermal stability while maintaining high electrochemical and mechanical performance. In this review, the fundamentals of HT-FSCs are outlined. A comprehensive overview of state-of-the-art progress and achievements in HT-FSCs, with a focus on thermally stable gel polymer electrolytes and electrode materials is provided. Finally, challenges and future perspectives regarding HT-FSCs are discussed, alongside strategies for elevating operational temperatures and performance.This review offers both theoretical foundations and practical guidelines for designing and manufacturing HT-FSCs, further promoting their widespread adoption across diverse fields. 展开更多
关键词 Flexible supercapacitors High-temperature tolerance Gel polymer electrolytes Electrode materials
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Fault-tolerant distributed fusion of PDFs using KLDs-induced functional FCM clustering
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作者 Zheng WEI Zhansheng DUAN 《Chinese Journal of Aeronautics》 2025年第7期493-506,共14页
In distributed fusion,when one or more sensors are disturbed by faults,a common problem is that their local estimations are inconsistent with those of other fault-free sensors.Most of the existing fault-tolerant distr... In distributed fusion,when one or more sensors are disturbed by faults,a common problem is that their local estimations are inconsistent with those of other fault-free sensors.Most of the existing fault-tolerant distributed fusion algorithms,such as the Covariance Union(CU)and Faulttolerant Generalized Convex Combination(FGCC),are only used for the point estimation case where local estimates and their associated error covariances are provided.A treatment with focus on the fault-tolerant distributed fusions of arbitrary local Probability Density Functions(PDFs)is lacking.For this problem,we first propose Kullback–Leibler Divergence(KLD)and reversed KLD induced functional Fuzzy c-Means(FCM)clustering algorithms to soft cluster all local PDFs,respectively.On this basis,two fault-tolerant distributed fusion algorithms of arbitrary local PDFs are then developed.They select the representing PDF of the cluster with the largest sum of memberships as the fused PDF.Numerical examples verify the better fault tolerance of the developed two distributed fusion algorithms. 展开更多
关键词 Distributed fusion Fault tolerance Probability Density Function(PDF) Functional fuzzy c-means clustering Kullback-Leibler Divergence(KLD)
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Comparison of Some Characteristics Between Phragmites communis and Its Salt Tolerant Variant 被引量:8
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作者 许祥明 叶和春 +1 位作者 李国凤 陈建林 《Acta Botanica Sinica》 CSCD 2000年第11期1126-1130,共5页
R5002_12, a salt tolerant line of Phragmites communis Trin., which was obtained from ethyl methane sulfonate (EMS) treated callus selected under saline stress, was compared with its wild line in respect to their m... R5002_12, a salt tolerant line of Phragmites communis Trin., which was obtained from ethyl methane sulfonate (EMS) treated callus selected under saline stress, was compared with its wild line in respect to their molecular biological, physiological and biochemical characterizations. Five arbitrary primers were screened which showed differences in DNA amplified polymorphism between the variant and its wild line. Some new proteins appeared in the salt tolerant plant under salt stress. Electrophoresis of peroxidase and esterase also showed some differences in isozyme expression between them. The chlorophyll content of the variant was higher than that of the original variety, whether the plants were under salt stress or not. 展开更多
关键词 Phragmites communis salt tolerant variant RAPD ISOZYME CHLOROPHYLL soluble protein
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Starch RVA Profile Properties for Cold Tolerant and Sensitive Cultivars of Japonica Rice at Different Altitudes 被引量:5
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作者 朱振华 金基永 +6 位作者 袁平荣 赵国珍 苏振喜 世荣 邹茜 杨世准 戴陆园 《Agricultural Science & Technology》 CAS 2011年第12期1831-1836,共6页
[Objective] By investigating of change rule rice starch RVA profile properties and the influence of cold tolerance on rice quality,the aim was to provide scientific references to the breeding of new cold-tolerant japo... [Objective] By investigating of change rule rice starch RVA profile properties and the influence of cold tolerance on rice quality,the aim was to provide scientific references to the breeding of new cold-tolerant japonica rice varieties with high quality in the Yunnan plateau.[Method] Four cold-tolerant and five cold-sensitive japonica rice cultivars were grown at three locations with different altitudes in Yunnan plateau to investigate rice starch RVA profile characteristics.[Result] The results showed that with increasing altitude,the setback viscosity in cold-sensitive cultivars increased significantly,while the peak viscosity and breakdown viscosity decreased significantly.However,the peak viscosity and breakdown viscosity in cold-tolerant cultivars initially decreased and then gradually increased with rising altitude,whereas the setback viscosity initially increased and then decreased.[Conclusion] The starch RVA parameters of cold-tolerant cultivars were less sensitive to different environments than those of cold-sensitive cultivars.Cooking and eating quality of cold-tolerant cultivars had relatively stable trends with rising altitude,whereas cooking and eating quality of cold-sensitive cultivars had a trend toward inferior. 展开更多
关键词 Japonica rice Cold tolerance Rice quality Starch viscosity ALTITUDE
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Screening of Drought-tolerant Brassica napus L.Varieties and Analysis on Their Physiologic and Biochemical Variations under Drought Stress 被引量:8
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作者 李淑娟 程量 +3 位作者 彭少丹 陈升位 王勤方 林良斌 《Agricultural Science & Technology》 CAS 2014年第4期596-604,615,共10页
[Objective] The aim of this study was to screen drought-tolerant Brassica napus L. germplasm resources by analyzing their physiological and biochemical changes under drought stress. [Method] Forty varieties of B. napu... [Objective] The aim of this study was to screen drought-tolerant Brassica napus L. germplasm resources by analyzing their physiological and biochemical changes under drought stress. [Method] Forty varieties of B. napus varieties were cultured under PEG-6000 osmotic stress and extreme drought stress in pots, re- spectively. Then, the contents of chlorophyll, carotenoid, proline, malondialdehyde (MDA), soluble sugar, soluble protein, and the activities of superoxide dismutase (SOD), catalase(CAT), peroxidase(POD) were measured under drought stress. [Result] Sever- al drought-tolerant varieties of B. napus were screened out: YAU200908, Xiangyou No.15, YAU200903, YAU200907, YAU200906 and YAU200904. Physiological and biochemical analysis showed that, the contents of chlorophyll and carotenoid de- creased with drought stress increasing; the contents of proline, soluble sugar, solu- ble protein, MDA and the activities of SOD,CAT, POD raised with drought stress in- creasing. [Conclusion] In the rapeseed varieties with stronger drought tolerance, the decrease in carotenoid content and the increase in proline content, soluble sugar content, MDA content, SOD activity, CAT activity were more obvious, so all these physiological and biochemical indices can be used to evaluate the drought tolerance of rapeseed. 展开更多
关键词 Brassica napus L. Drought tolerance Drought stress Physiologic and biochemical changes
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Effects of High Temperature Stress on Growth of Stress-Tolerant Rice Seedlings with Resistibility 被引量:4
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作者 张晓晶 张思远 +1 位作者 李春青 张文会 《Agricultural Science & Technology》 CAS 2014年第4期576-578,584,共4页
Two heat-tolerant rice varieties, N5 and TQ, were chosen as test materi- als. Specifically, rice seedlings (leaf age at 2.1), cultivated in room, were treated at 40 ℃ for 7 d and some indices were measured, includi... Two heat-tolerant rice varieties, N5 and TQ, were chosen as test materi- als. Specifically, rice seedlings (leaf age at 2.1), cultivated in room, were treated at 40 ℃ for 7 d and some indices were measured, including plant height, dry weight, leaf color, proline, malondialdehyde and conductivity. The results showed that high temperature advanced the growth of N5 seedlings, for example, plant height, root length and dry weight of ground parts all increased. However, high temperature prevented TQ seedlings growth, plant height in particular. Furthermore, high temper- ature treatment increased the content of chlorophyll of N5 and had none effects on PSII of N5, with little damages on membrane system. On the other hand, high temperature actually reduced PSII activity of TQ, and seriously damaged TQ mem- brane system. It is speculated that the differences of the two varieties lie on pro- duction or removing capacity of reactive oxide species. 展开更多
关键词 High temperature stress Rice seedlings TOLERANCE
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Screening and Evaluation of Salt Tolerant Varieties in Peanut 被引量:3
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作者 沈一 刘永惠 陈志德 《Agricultural Science & Technology》 CAS 2014年第4期542-545,共4页
The selection and application of salt tolerance varieties in peanut is impor- tant for the exploitation of saline soil. In this study, 41 peanut varieties were select- ed for the evaluation of salt tolerance in both g... The selection and application of salt tolerance varieties in peanut is impor- tant for the exploitation of saline soil. In this study, 41 peanut varieties were select- ed for the evaluation of salt tolerance in both germination and young seedling stage. The results showed the germination and growth of peanut were significantly inhibited by salt stress, which were enhanced by salt concentration increasing. The 0.5% NaCI was selected as the most suitable concentration for further identification, and the characters in germination stage (including the relative germination potential, relative germination rate and germination index) and young seedling stage (including relative main root length, seedling height, fresh weight, dry weight, et aL) were measured. Cluster analysis showed the varieties could be divided into different groups, and 9 and 3 salt-tolerant varieties were identified in the two stages, respec- tively, including two varieties performed well in both two stages, which could be useful for the breeding of new salt tolerance varieties and the study of salt toler- ance mechanism. 展开更多
关键词 PEANUT Salt tolerance EVALUATION Germination stage Young seedling stage
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FAULT-TOLERANT INTEGRATED NAVIGATION SYSTEM BASED ON NEURONS 被引量:1
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作者 马昕 袁信 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 1998年第2期4-7,共4页
In this paper, the multisensor data fusion technique of a fault tolerant integrated navigation system is discussed. A neural approach for data fusion is proposed for multisensor integrated systems. The simulation res... In this paper, the multisensor data fusion technique of a fault tolerant integrated navigation system is discussed. A neural approach for data fusion is proposed for multisensor integrated systems. The simulation results show that this neural approach for data fusion is feasible. 展开更多
关键词 navigation system NEURON data fusion fault tolerant
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Identification and Cu Enrichment Capacity of TLSB_2-K, a Cu-tolerant Strain 被引量:1
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作者 康薇 郑进 《Agricultural Science & Technology》 CAS 2014年第12期2081-2084,2144,共5页
[Objective] The Cu-tolerance and Cu enrichment capacity of TLSB2-K were investigated. [Method] The previously isolated TLSB2-K strain was identified though morphological observation, gram staining and 16S rDNA sequenc... [Objective] The Cu-tolerance and Cu enrichment capacity of TLSB2-K were investigated. [Method] The previously isolated TLSB2-K strain was identified though morphological observation, gram staining and 16S rDNA sequence alignment. In ad- dition, the effects of temperature, pH and osmotic pressure on the growth of strain were also investigated by using shaking culture. The Cu-tolerance and Cu enrich- ment capacity of TLSB2-K strain under Cu stress were also studied. [Result] The results showed TLSB2-K belongs to Bacillus spp., and its optimum growth conditions were as follows: temperature, 27 ~C; pH, 7.0; osmotic pressure, 1.1% NaCI. When the Cu concentration ranged from 100 mg/L to 500 mg/L, the strain grew well; when the Cu concentration ranged from 100 mg/L to 400 mg/L, the Cu content in bacteria was increased with the increase of Cu concentration; when the Cu con- centration was 400 mg/L and the incubation time was 30 h, the Cu content in bac- teria reached the peak (2 250 mg/kg); the highest tolerant concentration was 700 mg/L. [Conclusion] TLSB2-K strain had relatively high Cu tolerance and Cu enrich- ment capacity. They had important theoretical research and engineering application values. 展开更多
关键词 Soil contamination Cu tolerance Bacillus cereus Molecular identifica- tion Enrichment capacity
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A Novel Radiation Tolerant SOI Isolation Structure
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作者 赵洪辰 海潮和 +2 位作者 韩郑生 钱鹤 司红 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2005年第7期1291-1294,共4页
A novel radiation tolerant SOI isolation structure,consisting of thin SiO2/polysilicon/field SiO2 multilayers,is proposed. A device with this structure does not show obvious changes in subthreshold characteristics and... A novel radiation tolerant SOI isolation structure,consisting of thin SiO2/polysilicon/field SiO2 multilayers,is proposed. A device with this structure does not show obvious changes in subthreshold characteristics and leakage current,indicating a superior radiation tolerance to traditional LOCOS. 展开更多
关键词 isolation structure radiation tolerance SOI
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Regulatory T cells in neurological disorders and tissue regeneration:Mechanisms of action and therapeutic potentials 被引量:1
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作者 Jing Jie Xiaomin Yao +5 位作者 Hui Deng Yuxiang Zhou Xingyu Jiang Xiu Dai Yumin Yang Pengxiang Yang 《Neural Regeneration Research》 2026年第4期1277-1291,共15页
Regulatory T cells,a subset of CD4^(+)T cells,play a critical role in maintaining immune tolerance and tissue homeostasis due to their potent immunosuppressive properties.Recent advances in research have highlighted t... Regulatory T cells,a subset of CD4^(+)T cells,play a critical role in maintaining immune tolerance and tissue homeostasis due to their potent immunosuppressive properties.Recent advances in research have highlighted the important therapeutic potential of Tregs in neurological diseases and tissue repair,emphasizing their multifaceted roles in immune regulation.This review aims to summarize and analyze the mechanisms of action and therapeutic potential of Tregs in relation to neurological diseases and neural regeneration.Beyond their classical immune-regulatory functions,emerging evidence points to non-immune mechanisms of regulatory T cells,particularly their interactions with stem cells and other non-immune cells.These interactions contribute to optimizing the repair microenvironment and promoting tissue repair and nerve regeneration,positioning non-immune pathways as a promising direction for future research.By modulating immune and non-immune cells,including neurons and glia within neural tissues,Tregs have demonstrated remarkable efficacy in enhancing regeneration in the central and peripheral nervous systems.Preclinical studies have revealed that Treg cells interact with neurons,glial cells,and other neural components to mitigate inflammatory damage and support functional recovery.Current mechanistic studies show that Tregs can significantly promote neural repair and functional recovery by regulating inflammatory responses and the local immune microenvironment.However,research on the mechanistic roles of regulatory T cells in other diseases remains limited,highlighting substantial gaps and opportunities for exploration in this field.Laboratory and clinical studies have further advanced the application of regulatory T cells.Technical advances have enabled efficient isolation,ex vivo expansion and functionalization,and adoptive transfer of regulatory T cells,with efficacy validated in animal models.Innovative strategies,including gene editing,cell-free technologies,biomaterial-based recruitment,and in situ delivery have expanded the therapeutic potential of regulatory T cells.Gene editing enables precise functional optimization,while biomaterial and in situ delivery technologies enhance their accumulation and efficacy at target sites.These advancements not only improve the immune-regulatory capacity of regulatory T cells but also significantly enhance their role in tissue repair.By leveraging the pivotal and diverse functions of Tregs in immune modulation and tissue repair,regulatory T cells–based therapies may lead to transformative breakthroughs in the treatment of neurological diseases. 展开更多
关键词 demyelinating diseases gene editing immune regulation immune tolerance neural regeneration neurological diseases non-immune mechanisms regulatory T cells stem cells STROKE tissue homeostasis tissue repair
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Fault tolerant control of electric pitch control system based on single current detection
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作者 李宏伟 付勃 +2 位作者 董海鹰 杨立霞 王睿敏 《Journal of Measurement Science and Instrumentation》 CAS CSCD 2016年第1期63-70,共8页
In view of the current sensors failure in electric pitch system,a variable universe fuzzy fault tolerant control method of electric pitch control system based on single current detection is proposed.When there is sing... In view of the current sensors failure in electric pitch system,a variable universe fuzzy fault tolerant control method of electric pitch control system based on single current detection is proposed.When there is single or two-current sensor fault occurs,based on the proposed method the missing current information can be reconstructed by using direct current(DC)bus current sensor and the three-phase current can be updated in time within any two adjacent sampling periods,so as to ensure stability of the closed-loop system.And then the switchover and fault tolerant control of fault current sensor would be accomplished by fault diagnosis method based on adaptive threshold judgment.For the reconstructed signal error caused by the modulation method and the main control target of electric pitch system,a variable universe fuzzy control method is used in the speed loop,which can improve the anti-disturbance ability to load variation,and the robustness of fault tolerance system.The results show that the fault tolerant control method makes the variable pitch control system still has ideal control characteristics in case of sensor failure although part of the system performance is lost,thus the correctness of the proposed method is verified. 展开更多
关键词 electric pitch control fault tolerant control variable universe fuzzy control single current detection
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Methanol Tolerant FeTPP-Pt/C Co-catalysts for the Electroreduction of Oxygen
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作者 XuGuangLI XiangQingLI 《Chinese Chemical Letters》 SCIE CAS CSCD 2002年第11期1125-1126,共2页
It was found for the first time that iron tetraphenylporphyrin (FeTPP)-Pt/C showed the good activity for the electroreduction of oxygen and methanol tolerant ability. Their perfor- mances were related to the heat-tre... It was found for the first time that iron tetraphenylporphyrin (FeTPP)-Pt/C showed the good activity for the electroreduction of oxygen and methanol tolerant ability. Their perfor- mances were related to the heat-treatment temperature. 展开更多
关键词 FeTPP PT oxygen reduction methanol tolerant.
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Lactylation modification of prostate apoptosis response protein-4(PAR-4)p otential driving immune tolerance of hepatocellular carcinoma cells
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作者 Xue-Qin Wu Meng-Sen Li 《Cancer Advances》 2026年第1期1-4,共4页
Post-translational modifications(PTMs)regulate the occurrence and development of cancer,and lactylation modification is a new form of PTMs.Recent studies have found that lactic acid modification can regulate the immun... Post-translational modifications(PTMs)regulate the occurrence and development of cancer,and lactylation modification is a new form of PTMs.Recent studies have found that lactic acid modification can regulate the immune tolerance of cancer cells.The classical theory holds that prostate apoptosis response-4(PAR-4)is a tumor suppressor protein.However,our recent research has found that PAR-4 has a biological function of promoting cancer in hepatocellular carcinoma(HCC),and our analysis shows that PAR-4 can be modified of lactic acid.These research evidences suggest that PAR-4 lactylation modification may drive immune tolerance in HCC.Therefore,inhibiting PAR-4 lactylation modification is very likely to increase the sensitivity of HCC to immunotherapy. 展开更多
关键词 hepatocellular carcinoma lactylation promoting cancer prostate apoptosis response protein lactic acid modification immune tolerance lactylation modification regulate immune tolerance
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