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The groundbreaking discovery of peripheral immune tolerance:identifying Treg cells and the FOXP3 gene,and their therapeutic potential
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作者 Yongfen Xu Cheng Peng Bin Li 《Blood Science》 2025年第4期115-117,共3页
Recently,the Nobel Prize in Physiology or Medicine 2025 was awarded jointly to Mary E.Brunkow,Fred Ramsdell,and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance,a delicate p... Recently,the Nobel Prize in Physiology or Medicine 2025 was awarded jointly to Mary E.Brunkow,Fred Ramsdell,and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance,a delicate process that ensures the immune system targets pathogens without attacking the body’s own cells.The core of their research is regulatory T cells(Tregs),which act as the“brakes”or security guards of the immune system. 展开更多
关键词 peripheral immune tolerance peripheral immune tolerancea therapeutic potential foxp gene immune system regulatory t cells regulatory t cells tregs which immune system targets pathogens
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