Recently,the Nobel Prize in Physiology or Medicine 2025 was awarded jointly to Mary E.Brunkow,Fred Ramsdell,and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance,a delicate p...Recently,the Nobel Prize in Physiology or Medicine 2025 was awarded jointly to Mary E.Brunkow,Fred Ramsdell,and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance,a delicate process that ensures the immune system targets pathogens without attacking the body’s own cells.The core of their research is regulatory T cells(Tregs),which act as the“brakes”or security guards of the immune system.展开更多
基金support from grant Noncommunicable Chronic Diseases-National Science and Technology Major Project(2023ZD0501605)National Natural Science Foundation of China(32130041,82441047,82241222)+1 种基金Innovative research team of high-level local universities in Shanghai(SHSMU-ZDCX20210601)Shenzhen Science and Technology Program KQTD20210811090115019.
文摘Recently,the Nobel Prize in Physiology or Medicine 2025 was awarded jointly to Mary E.Brunkow,Fred Ramsdell,and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance,a delicate process that ensures the immune system targets pathogens without attacking the body’s own cells.The core of their research is regulatory T cells(Tregs),which act as the“brakes”or security guards of the immune system.