This paper reports that the designed optical polarization mode dispersion compensator shows a good performance under the real-time variation of differential group delay, state of polarization and principal state of po...This paper reports that the designed optical polarization mode dispersion compensator shows a good performance under the real-time variation of differential group delay, state of polarization and principal state of polarization in a （40×43）-Gb/s dense-wavelength-multiplexing, 1200-km enhanced return-to-zero differential-quadrature-phase-shift- keying （RZ-DQPSK） system. The polarization mode dispersion tolerance of the system is improved by 26 ps using the optical polarization mode dispersion compensator. The short and long time stabilities are tested with the bit error ratio recorded.展开更多
Low temperature and sparse light in early spring is one of the factors causing reduction for rice production. So it is important to develop cold tolerance cultivars. In the present study, cold tolerance characters of ...Low temperature and sparse light in early spring is one of the factors causing reduction for rice production. So it is important to develop cold tolerance cultivars. In the present study, cold tolerance characters of 36 parents and 423 rice lines from 68 hybrid groups were investigated at seedling stage under low tempera- ture and sparse light conditions in field. There were 10 parent accessions with strong cold tolerance of level 1. Among them, 3 were common wild rice accessions; 4 were japonica rice cultivars; 2 were indica rice; 1 was offspring from hybrid be- tween indica and japonica.There were 33 lines with strong cold tolerance of level 1 from the hybrid groups of common wild rice,and 15 from the hybrid groups of IRBB5, and only 3 from the hybrid groups of BPHR96. There were abundant cold tolerance resources in rice germplasm. It was feasible to develop cold tolerance cul- tivars from the hybrids among common wild rice, japonica cultivars and indica culti- vars.展开更多
Aim Aconitine and its structurally-related diterpenoid alkaloids have been shown to interact differential- ly with neuronal voltage-dependent sodium channels and be responsible for their analgesia and toxicity. Bulley...Aim Aconitine and its structurally-related diterpenoid alkaloids have been shown to interact differential- ly with neuronal voltage-dependent sodium channels and be responsible for their analgesia and toxicity. Bulleya- conitine A （ BAA or BLA） is an aconitine analog and has been prescribed for the management of pain. The present study aimed to evaluate the inhibitory effects of BAA on pain hypersensitivity and morphine anti-nociceptive toler- ance, and explore whether the release of dynorphin A from spinal microglia was associated with its mechanism of actions. Methods Rat models of neuropathic pain, formalin test and bone cancer pain were used, and spinal dynorphin A level and expression were measured. Sample size of animals was six in each study group. Resultes A single intrathecal or subcutaneous （but not intraventricular or local） injection of BAA blocked spinal nerve liga- tion-induced painful neuropathy, bone cancer-induced pain and formalin-induced hyperalgesia by 60% - 100% with the ED50 values of 94 - 126 ng/rat （intrathecal） and 42 - 59 μg · kg^-1 （ subcutaneous）, respectively. Follow- ing chronic treatment, BAA did not induce either self-tolerance to anti-nociception or cross-tolerance to morphine anti-nociception, and completely prevented morphine tolerance. Spinal BAA anti-nociception, but not neurotoxici- ty, was completely blocked by the specific microglial inhibitor minocycline. In a minocycline-sensitive and lido- BAA stimulated the release of dynorphin A from the spinal cord, and the caine- or ropivacaine-insensitive manner, primary culture of microglia but not from neurons or astrocytes. The blockade effects of BAA on nociception and morphine tolerance were completely blocked by the specific dynorphin A antiserum and/or K-opioid receptor antago- nist. Conclusions Our results demonstrated that BAA eliminated pain hypersensitivity and morphine tolerance through the direct stimulation of dynorphin A release from spinal microglia, which was not dependent on the interac- tions with sodium channels.展开更多
Toxic heavy metals are increasingly accumu- lating in the environment worldwide and are considered to be life threatening contaminants. The biosorption of mercury and lead by marine actinomycetes isolated from marine ...Toxic heavy metals are increasingly accumu- lating in the environment worldwide and are considered to be life threatening contaminants. The biosorption of mercury and lead by marine actinomycetes isolated from marine sediment collected from the Bay of Bengal coast of Puducherry, India, was evaluated. The maximum tolerance concentration （MTC） of Streptomyces sp. was determined by a well diffusion method and a broth dilution method. The effects of the initial metal ion concentration, the pH and the biomass dosage on the biosorption of mercury and lead ions were investigated. The MTC of the isolate to metals was 200 mg. L 1 for mercury and 1800 mg. L-1 for lead. At neutral pH, the isolate had a maximum biosorption of metal ions of 200 mg.L 1 and 150 mg.L~ for mercury and lead respectively. Fourier transform infrared （FTIR） absorption spectra showed the chemical interactions between the functional groups in the biomass such as hydroxyl （- OH）, amine （-NH2）, earboxyl （- COOH） and the metal ions. The isolate was further characterized by molecular taxonomy and identified as a member of the genus Streptomyces. Based on the phenotypic and phylogenetic analysis, the strain was classified as a new species of the genus Streptomyces and designated as Streptomyces VITSVK9 sp. （HM137310）. A blast search of the 16S rDNA sequence of the strain showed the most similarity （95%） with Streptomyces sp. A515 Ydz-FQ （EU384279）. Based on the results, it can be concluded that this marine Streptomyces could be used as a biosorbent for the removal of heavy metal ions from aqueous environments.展开更多
基金Project supported by the Huawei Technology Project (Grant No.YBON2008014)the National "863" High Technology Projects (Grant No.2009AA01Z224)
文摘This paper reports that the designed optical polarization mode dispersion compensator shows a good performance under the real-time variation of differential group delay, state of polarization and principal state of polarization in a （40×43）-Gb/s dense-wavelength-multiplexing, 1200-km enhanced return-to-zero differential-quadrature-phase-shift- keying （RZ-DQPSK） system. The polarization mode dispersion tolerance of the system is improved by 26 ps using the optical polarization mode dispersion compensator. The short and long time stabilities are tested with the bit error ratio recorded.
基金Supported by Guangxi Natural Science Foundation Item,China(2013GXNSFBA019-066)Guangxi Science Research and Technology Development Project,China(Guikezhong14121001-2-4)Nanning Municipal Science Research and Technology Development Plan Item,China(20132304)~~
文摘Low temperature and sparse light in early spring is one of the factors causing reduction for rice production. So it is important to develop cold tolerance cultivars. In the present study, cold tolerance characters of 36 parents and 423 rice lines from 68 hybrid groups were investigated at seedling stage under low tempera- ture and sparse light conditions in field. There were 10 parent accessions with strong cold tolerance of level 1. Among them, 3 were common wild rice accessions; 4 were japonica rice cultivars; 2 were indica rice; 1 was offspring from hybrid be- tween indica and japonica.There were 33 lines with strong cold tolerance of level 1 from the hybrid groups of common wild rice,and 15 from the hybrid groups of IRBB5, and only 3 from the hybrid groups of BPHR96. There were abundant cold tolerance resources in rice germplasm. It was feasible to develop cold tolerance cul- tivars from the hybrids among common wild rice, japonica cultivars and indica culti- vars.
文摘Aim Aconitine and its structurally-related diterpenoid alkaloids have been shown to interact differential- ly with neuronal voltage-dependent sodium channels and be responsible for their analgesia and toxicity. Bulleya- conitine A （ BAA or BLA） is an aconitine analog and has been prescribed for the management of pain. The present study aimed to evaluate the inhibitory effects of BAA on pain hypersensitivity and morphine anti-nociceptive toler- ance, and explore whether the release of dynorphin A from spinal microglia was associated with its mechanism of actions. Methods Rat models of neuropathic pain, formalin test and bone cancer pain were used, and spinal dynorphin A level and expression were measured. Sample size of animals was six in each study group. Resultes A single intrathecal or subcutaneous （but not intraventricular or local） injection of BAA blocked spinal nerve liga- tion-induced painful neuropathy, bone cancer-induced pain and formalin-induced hyperalgesia by 60% - 100% with the ED50 values of 94 - 126 ng/rat （intrathecal） and 42 - 59 μg · kg^-1 （ subcutaneous）, respectively. Follow- ing chronic treatment, BAA did not induce either self-tolerance to anti-nociception or cross-tolerance to morphine anti-nociception, and completely prevented morphine tolerance. Spinal BAA anti-nociception, but not neurotoxici- ty, was completely blocked by the specific microglial inhibitor minocycline. In a minocycline-sensitive and lido- BAA stimulated the release of dynorphin A from the spinal cord, and the caine- or ropivacaine-insensitive manner, primary culture of microglia but not from neurons or astrocytes. The blockade effects of BAA on nociception and morphine tolerance were completely blocked by the specific dynorphin A antiserum and/or K-opioid receptor antago- nist. Conclusions Our results demonstrated that BAA eliminated pain hypersensitivity and morphine tolerance through the direct stimulation of dynorphin A release from spinal microglia, which was not dependent on the interac- tions with sodium channels.
文摘Toxic heavy metals are increasingly accumu- lating in the environment worldwide and are considered to be life threatening contaminants. The biosorption of mercury and lead by marine actinomycetes isolated from marine sediment collected from the Bay of Bengal coast of Puducherry, India, was evaluated. The maximum tolerance concentration （MTC） of Streptomyces sp. was determined by a well diffusion method and a broth dilution method. The effects of the initial metal ion concentration, the pH and the biomass dosage on the biosorption of mercury and lead ions were investigated. The MTC of the isolate to metals was 200 mg. L 1 for mercury and 1800 mg. L-1 for lead. At neutral pH, the isolate had a maximum biosorption of metal ions of 200 mg.L 1 and 150 mg.L~ for mercury and lead respectively. Fourier transform infrared （FTIR） absorption spectra showed the chemical interactions between the functional groups in the biomass such as hydroxyl （- OH）, amine （-NH2）, earboxyl （- COOH） and the metal ions. The isolate was further characterized by molecular taxonomy and identified as a member of the genus Streptomyces. Based on the phenotypic and phylogenetic analysis, the strain was classified as a new species of the genus Streptomyces and designated as Streptomyces VITSVK9 sp. （HM137310）. A blast search of the 16S rDNA sequence of the strain showed the most similarity （95%） with Streptomyces sp. A515 Ydz-FQ （EU384279）. Based on the results, it can be concluded that this marine Streptomyces could be used as a biosorbent for the removal of heavy metal ions from aqueous environments.
