A class of models for activity-driven networks is proposed in which nodes vary in two states： active and inactive. Only active nodes can receive links from others which represent instantaneous dynamical interactions....A class of models for activity-driven networks is proposed in which nodes vary in two states： active and inactive. Only active nodes can receive links from others which represent instantaneous dynamical interactions. The evolution of the network couples the addition of new nodes and state transitions of old ones. The active group changes with activated nodes entering and deactivated ones leaving. A general differential equation framework is developed to study the degree distribution of nodes of integrated networks where four different schemes are formulated.展开更多
This paper study the finite time internal synchronization and the external synchronization(hybrid synchronization)for duplex heterogeneous complex networks by time-varying intermittent control.There few study hybrid s...This paper study the finite time internal synchronization and the external synchronization(hybrid synchronization)for duplex heterogeneous complex networks by time-varying intermittent control.There few study hybrid synchronization of heterogeneous duplex complex networks.Therefore,we study the finite time hybrid synchronization of heterogeneous duplex networks,which employs the time-varying intermittent control to drive the duplex heterogeneous complex networks to achieve hybrid synchronization in finite time.To be specific,the switch frequency of the controllers can be changed with time by devise Lyapunov function and boundary function,the internal synchronization and external synchronization are achieved simultaneously in finite time.Finally,numerical examples are presented to illustrate the validness of theoretical results.展开更多
This paper investigates modified fixed-time synchronization(FxTS)of complex networks(CNs)with time-varying delays based on continuous and discontinuous controllers.First,for the sake of making the settling time(ST)of ...This paper investigates modified fixed-time synchronization(FxTS)of complex networks(CNs)with time-varying delays based on continuous and discontinuous controllers.First,for the sake of making the settling time(ST)of FxTS is independent of the initial values and parameters of the CNs,a modified fixed-time(FxT)stability theorem is proposed,where the ST is determined by an arbitrary positive number given in advance.Then,continuous controller and discontinuous controller are designed to realize the modified FxTS target of CNs.In addition,based on the designed controllers,CNs can achieve synchronization at any given time,or even earlier.And control strategies effectively solve the problem of ST related to the parameters of CNs.Finally,an appropriate simulation example is conducted to examine the effectiveness of the designed control strategies.展开更多
The dynamics of network power response play a crucial role in system stability.However,the integration of power electronic equipment leads to amplitude and angular frequency(abbreviated as"frequency")time-va...The dynamics of network power response play a crucial role in system stability.However,the integration of power electronic equipment leads to amplitude and angular frequency(abbreviated as"frequency")time-varying characteristics of the node voltage during dynamic processes.As a result,traditional calcu-lation methods for and characteristics of the power response of the network based on phasor and impe-dance lose their validity.Therefore,this paper undertakes mathematical calculations to reveal the power response of a network under excitation by voltage with time-varying amplitude and frequency(TVAF),relying on the original mathematical relationships and superimposed step response.Then,the multi-timescale characteristics of both the active and reactive power of the network are explored physically.Additionally,this paper reveals a new phenomenon of storing and releasing the active and reactive power of the network.To meet practical engineering requirements,a simplified power expression is presented.Finally,the theoretical analysis is validated through time-domain simulations.展开更多
This paper investigates a class of constrained distributed zeroth-order optimization(ZOO) problems over timevarying unbalanced graphs while ensuring privacy preservation among individual agents. Not taking into accoun...This paper investigates a class of constrained distributed zeroth-order optimization(ZOO) problems over timevarying unbalanced graphs while ensuring privacy preservation among individual agents. Not taking into account recent progress and addressing these concerns separately, there remains a lack of solutions offering theoretical guarantees for both privacy protection and constrained ZOO over time-varying unbalanced graphs.We hereby propose a novel algorithm, termed the differential privacy(DP) distributed push-sum based zeroth-order constrained optimization algorithm(DP-ZOCOA). Operating over time-varying unbalanced graphs, DP-ZOCOA obviates the need for supplemental suboptimization problem computations, thereby reducing overhead in comparison to distributed primary-dual methods. DP-ZOCOA is specifically tailored to tackle constrained ZOO problems over time-varying unbalanced graphs,offering a guarantee of convergence to the optimal solution while robustly preserving privacy. Moreover, we provide rigorous proofs of convergence and privacy for DP-ZOCOA, underscoring its efficacy in attaining optimal convergence without constraints. To enhance its applicability, we incorporate DP-ZOCOA into the federated learning framework and formulate a decentralized zeroth-order constrained federated learning algorithm(ZOCOA-FL) to address challenges stemming from the timevarying imbalance of communication topology. Finally, the performance and effectiveness of the proposed algorithms are thoroughly evaluated through simulations on distributed least squares(DLS) and decentralized federated learning(DFL) tasks.展开更多
Dear Editor,This letter is concerned with the problem of time-varying formation tracking for heterogeneous multi-agent systems(MASs) under directed switching networks. For this purpose, our first step is to present so...Dear Editor,This letter is concerned with the problem of time-varying formation tracking for heterogeneous multi-agent systems(MASs) under directed switching networks. For this purpose, our first step is to present some sufficient conditions for the exponential stability of a particular category of switched systems.展开更多
BACKGROUND Non-suicidal self-injury(NSSI)is common among adolescents with depressive disorders and poses a major public health challenge.Rumination,a key cognitive feature of depression,includes different subtypes tha...BACKGROUND Non-suicidal self-injury(NSSI)is common among adolescents with depressive disorders and poses a major public health challenge.Rumination,a key cognitive feature of depression,includes different subtypes that may relate to NSSI through distinct psychological mechanisms.However,how these subtypes interact with specific NSSI behaviors remains unclear.AIM To examine associations between rumination subtypes and specific NSSI behaviors in adolescents.METHODS We conducted a cross-sectional study with 305 hospitalized adolescents diagnosed with depressive disorders.The subjects ranged from 12-18 years in age.Rumi-nation subtypes were assessed using the Ruminative Response Scale,and 12 NSSI behaviors were evaluated using a validated questionnaire.Network analysis was applied to explore symptom-level associations and identify central symptoms.RESULTS The network analysis revealed close connections between rumination subtypes and NSSI behaviors.Brooding was linked to behaviors such as hitting objects and burning.Scratching emerged as the most influential NSSI symptom.Symptomfocused rumination served as a key bridge connecting rumination and NSSI.CONCLUSION Symptom-focused rumination and scratching were identified as potential intervention targets.These findings highlight the psychological significance of specific cognitive-behavioral links in adolescent depression and suggest directions for tailored prevention and treatment.However,the cross-sectional,single-site design limits causal inference and generalizability.Future longitudinal and multi-center studies are needed to confirm causal pathways and verify the generalizability of the findings to broader adolescent populations.展开更多
Background:Wenqing Yin(WQY)is a classic prescription used to treat skin diseases like atopic dermatitis(AD)in China,and the aim of this study is to investigate the therapeutic effects and molecular mechanisms of WQY o...Background:Wenqing Yin(WQY)is a classic prescription used to treat skin diseases like atopic dermatitis(AD)in China,and the aim of this study is to investigate the therapeutic effects and molecular mechanisms of WQY on AD.Methods:The DNFB-induced mouse models of AD were established to investigate the therapeutic effects of WQY on AD.The symptoms of AD in the ears and backs of the mice were assessed,while inflammatory factors in the ear were quantified using quantitative real-time-polymerase chain reaction(qRT-PCR),and the percentages of CD4^(+)and CD8^(+)cells in the spleen were analyzed through flow cytometry.The compounds in WQY were identified using ultra-performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS)analysis and the key targets and pathways of WQY to treat AD were predicted by network pharmacology.Subsequently,the key genes were tested and verified by qRT-PCR,and the potential active components and target proteins were verified by molecular docking.Results:WQY relieved the AD symptoms and histopathological injuries in the ear and back skin of mice with AD.Meanwhile,WQY significantly reduced the levels of inflammatory factors IL-6 and IL-1βin ear tissue,as well as the ratio of CD4^(+)/CD8^(+)cells in spleen.Additionally,a total of 142 compounds were identified from the water extract of WQY by UPLC-Orbitrap-MS/MS.39 key targets related to AD were screened out by network pharmacology methods.The KEGG analysis indicated that the effects of WQY were primarily mediated through pathways associated with Toll-like receptor signaling and T cell receptor signaling.Moreover,the results of qRT-PCR demonstrated that WQY significantly reduced the mRNA expressions of IL-4,IL-10,GATA3 and FOXP3,and molecular docking simulation verified that the active components of WQY had excellent binding abilities with IL-4,IL-10,GATA3 and FOXP3 proteins.Conclusion:The present study demonstrated that WQY effectively relieved AD symptoms in mice,decreased the inflammatory factors levels,regulated the balance of CD4^(+)and CD8^(+)cells,and the mechanism may be associated with the suppression of Th2 and Treg cell immune responses.展开更多
This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for ...This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for identifying critical failure modes and their root causes,while BN introduces flexibility in probabilistic reasoning,enabling dynamic updates based on new evidence.This dual methodology overcomes the limitations of static FTA models,offering a comprehensive framework for system reliability analysis.Critical failures,including External Leakage(ELU),Failure to Start(FTS),and Overheating(OHE),were identified as key risks.By incorporating redundancy into high-risk components such as pumps and batteries,the likelihood of these failures was significantly reduced.For instance,redundant pumps reduced the probability of ELU by 31.88%,while additional batteries decreased the occurrence of FTS by 36.45%.The results underscore the practical benefits of combining FTA and BN for enhancing system reliability,particularly in maritime applications where operational safety and efficiency are critical.This research provides valuable insights for maintenance planning and highlights the importance of redundancy in critical systems,especially as the industry transitions toward more autonomous vessels.展开更多
A new approach to damage classification for health monitoring of a time-varylng system is presented. The functional-series time-dependent auto regressive moving average （FS-TARMA） time series model is applied to the...A new approach to damage classification for health monitoring of a time-varylng system is presented. The functional-series time-dependent auto regressive moving average （FS-TARMA） time series model is applied to the vibration signal observed in the time-varying system for estimating the TAR/TMA parameters and the innovation variance. These parameters are the functions of the time, represented by a group of projection coefficients on the certain functional subspace with specific basis functions. The estimated TAR/TMA parameters and the innovation variance are further used to calculate the latent components （LCs） as the more informative data for health monitoring evaluation, based on an eigenvalue decomposition technique. LCs are then combined and reduced to numerical values （NVs） as feature sets, which are input to a probabilistic neural network （PNN） for the damage classification. For the evaluation of the proposed method, numerical simulations of the damage classification for a tlme-varylng system are used, in which different classes of damage are modeled by the mass or stiffness reductions. It is demonstrated that the method can identify the damages in the course of operation and the change of parameters on the time-varying background of the system.展开更多
In this paper,a distributed stochastic approximation algorithm is proposed to track the dynamic root of a sum of time-varying regression functions over a network.Each agent updates its estimate by using the local obse...In this paper,a distributed stochastic approximation algorithm is proposed to track the dynamic root of a sum of time-varying regression functions over a network.Each agent updates its estimate by using the local observation,the dynamic information of the global root,and information received from its neighbors.Compared with similar works in optimization area,we allow the observation to be noise-corrupted,and the noise condition is much weaker.Furthermore,instead of the upper bound of the estimate error,we present the asymptotic convergence result of the algorithm.The consensus and convergence of the estimates are established.Finally,the algorithm is applied to a distributed target tracking problem and the numerical example is presented to demonstrate the performance of the algorithm.展开更多
In this work,a frame work for time-varying channel modeling and simulation is proposed by using neural network(NN)to overcome the shortcomings in geometry based stochastic model(GBSM)and simulation approach.Two NN mod...In this work,a frame work for time-varying channel modeling and simulation is proposed by using neural network(NN)to overcome the shortcomings in geometry based stochastic model(GBSM)and simulation approach.Two NN models are developed for modeling of path loss together with shadow fading(SF)and joint small scale channel parameters.The NN models can predict path loss plus SF and small scale channel parameters accurately compared with measurement at 26 GHz performed in an outdoor microcell.The time-varying path loss and small scale channel parameters generated by the NN models are proposed to replace the empirical path loss and channel parameter random numbers in GBSM-based framework to playback the measured channel and match with its environment.Moreover,the sparse feature of clusters,delay and angular spread,channel capacity are investigated by a virtual array measurement at 28 GHz in a large waiting hall.展开更多
Abstract--In this paper, an adaptive neural network (NN) control approach is proposed for nonlinear pure-feedback sys- tems with time-varying full state constraints. The pure-feedback systems of this paper are assumed...Abstract--In this paper, an adaptive neural network (NN) control approach is proposed for nonlinear pure-feedback sys- tems with time-varying full state constraints. The pure-feedback systems of this paper are assumed to possess nonlinear function uncertainties. By using the mean value theorem, pure-feedback systems can be transformed into strict feedback forms. For the newly generated systems, NNs are employed to approximate unknown items. Based on the adaptive control scheme and backstepping algorithm, an intelligent controller is designed. At the same time, time-varying Barrier Lyapunov functions (BLFs) with error variables are adopted to avoid violating full state constraints in every step of the backstepping design. All closed- loop signals are uniformly ultimately bounded and the output tracking error converges to the neighborhood of zero, which can be verified by using the Lyapunov stability theorem. Two simulation examples reveal the performance of the adaptive NN control approach. Index TermsmAdaptive control, neural networks (NNs), non- linear pure-feedback systems, time-varying constraints.展开更多
Cascading failure can cause great damage to complex networks, so it is of great significance to improve the network robustness against cascading failure. Many previous existing works on load-redistribution strategies ...Cascading failure can cause great damage to complex networks, so it is of great significance to improve the network robustness against cascading failure. Many previous existing works on load-redistribution strategies require global information, which is not suitable for large scale networks, and some strategies based on local information assume that the load of a node is always its initial load before the network is attacked, and the load of the failure node is redistributed to its neighbors according to their initial load or initial residual capacity. This paper proposes a new load-redistribution strategy based on local information considering an ever-changing load. It redistributes the loads of the failure node to its nearest neighbors according to their current residual capacity, which makes full use of the residual capacity of the network. Experiments are conducted on two typical networks and two real networks, and the experimental results show that the new load-redistribution strategy can reduce the size of cascading failure efficiently.展开更多
This paper is concerned with the finite-time control problem for a class of networked control systems(NCSs) with short time-varying delays and sampling jitter.Considering a state feedback controller,the closed-loop NC...This paper is concerned with the finite-time control problem for a class of networked control systems(NCSs) with short time-varying delays and sampling jitter.Considering a state feedback controller,the closed-loop NCS is described as a discrete-time linear system model,and the uncertain parts reflect the effect of the the network-induced delays and short sampling jitter of the system dynamics.Then a robust approach is proposed to solve the finite-time stability and stabilization problems for the considered NCS.An illustrative example is provided to demonstrate the effectiveness of the proposed theoretical results.展开更多
In this paper, the global exponential robust stability of neural networks with ume-varying delays is investigated. By using nonnegative matrix theory and the Halanay inequality, a new sufficient condition for global e...In this paper, the global exponential robust stability of neural networks with ume-varying delays is investigated. By using nonnegative matrix theory and the Halanay inequality, a new sufficient condition for global exponential robust stability is presented. It is shown that the obtained result is different from or improves some existing ones reported in the literatures. Finally, some numerical examples and a simulation are given to show the effectiveness of the obtained result.展开更多
In this paper, the problem of the global exponential stability analysis is investigated for a class of recurrent neural networks （RNNs） with time-varying discrete and distributed delays. Due to a novel technique whe...In this paper, the problem of the global exponential stability analysis is investigated for a class of recurrent neural networks （RNNs） with time-varying discrete and distributed delays. Due to a novel technique when estimating the upper bound of the derivative of Lyapunov functional, we establish new exponential stability criteria in terms of LMIs. It is shown that the obtained criteria can provide less conservative results than some existing ones. Numerical examples are given to show the effectiveness of the proposed results.展开更多
In this paper, the problem of exponential synchronization of complex dynamical networks with Markovian jumping parameters using sampled-data and Mode-dependent probabilistic time-varying coupling delays is investigate...In this paper, the problem of exponential synchronization of complex dynamical networks with Markovian jumping parameters using sampled-data and Mode-dependent probabilistic time-varying coupling delays is investigated. The sam- pling period is assumed to be time-varying and bounded. The information of probability distribution of the time-varying delay is considered and transformed into parameter matrices of the transferred complex dynamical network model. Based on the condition, the design method of the desired sampled data controller is proposed. By constructing a new Lyapunov functional with triple integral terms, delay-distribution-dependent exponential synchronization criteria are derived in the form of linear matrix inequalities. Finally, two numerical examples are given to illustrate the effectiveness of the proposed methods.展开更多
This paper discusses H-infinity state feedback control for a networked control system with time-varying delays. Based on the flee-weighing matrix method, a dehy-dependent stability criterion satisfying a prescribed H-...This paper discusses H-infinity state feedback control for a networked control system with time-varying delays. Based on the flee-weighing matrix method, a dehy-dependent stability criterion satisfying a prescribed H-infinity norm bound is presented for an NCS with unknown, time-varying and bounded delays. And then, the criterion is transformed into sufficient conditions based on linear matrix inequalities for H-infinity control. The conditions thus obtained are also used to design an H-infinity state feedback controller. This design method is further extended to solve the design problem of robust H-infinity state feedback control. A numerical example demonstrates the validity of the method.展开更多
基金supported by the National Natural Science Foundation of China(Grant No.11665009)the Natural Science Research Project of Guizhou Provincial Education Bureau(Grant No.KY[2015]355)
文摘A class of models for activity-driven networks is proposed in which nodes vary in two states： active and inactive. Only active nodes can receive links from others which represent instantaneous dynamical interactions. The evolution of the network couples the addition of new nodes and state transitions of old ones. The active group changes with activated nodes entering and deactivated ones leaving. A general differential equation framework is developed to study the degree distribution of nodes of integrated networks where four different schemes are formulated.
基金Project supported by Jilin Provincial Science and Technology Development Plan(Grant No.20220101137JC).
文摘This paper study the finite time internal synchronization and the external synchronization(hybrid synchronization)for duplex heterogeneous complex networks by time-varying intermittent control.There few study hybrid synchronization of heterogeneous duplex complex networks.Therefore,we study the finite time hybrid synchronization of heterogeneous duplex networks,which employs the time-varying intermittent control to drive the duplex heterogeneous complex networks to achieve hybrid synchronization in finite time.To be specific,the switch frequency of the controllers can be changed with time by devise Lyapunov function and boundary function,the internal synchronization and external synchronization are achieved simultaneously in finite time.Finally,numerical examples are presented to illustrate the validness of theoretical results.
基金Supported by the National Natural Science Foundation of China(62476082)。
文摘This paper investigates modified fixed-time synchronization(FxTS)of complex networks(CNs)with time-varying delays based on continuous and discontinuous controllers.First,for the sake of making the settling time(ST)of FxTS is independent of the initial values and parameters of the CNs,a modified fixed-time(FxT)stability theorem is proposed,where the ST is determined by an arbitrary positive number given in advance.Then,continuous controller and discontinuous controller are designed to realize the modified FxTS target of CNs.In addition,based on the designed controllers,CNs can achieve synchronization at any given time,or even earlier.And control strategies effectively solve the problem of ST related to the parameters of CNs.Finally,an appropriate simulation example is conducted to examine the effectiveness of the designed control strategies.
基金supported in part by the National Natural Science Fundation of China(52225704 and 52107096).
文摘The dynamics of network power response play a crucial role in system stability.However,the integration of power electronic equipment leads to amplitude and angular frequency(abbreviated as"frequency")time-varying characteristics of the node voltage during dynamic processes.As a result,traditional calcu-lation methods for and characteristics of the power response of the network based on phasor and impe-dance lose their validity.Therefore,this paper undertakes mathematical calculations to reveal the power response of a network under excitation by voltage with time-varying amplitude and frequency(TVAF),relying on the original mathematical relationships and superimposed step response.Then,the multi-timescale characteristics of both the active and reactive power of the network are explored physically.Additionally,this paper reveals a new phenomenon of storing and releasing the active and reactive power of the network.To meet practical engineering requirements,a simplified power expression is presented.Finally,the theoretical analysis is validated through time-domain simulations.
基金supported in part by the National Key Research and Development Program of China(2022ZD0120001)the National Natural Science Foundation of China(62233004,62273090,62073076)the Jiangsu Provincial Scientific Research Center of Applied Mathematics(BK20233002)
文摘This paper investigates a class of constrained distributed zeroth-order optimization(ZOO) problems over timevarying unbalanced graphs while ensuring privacy preservation among individual agents. Not taking into account recent progress and addressing these concerns separately, there remains a lack of solutions offering theoretical guarantees for both privacy protection and constrained ZOO over time-varying unbalanced graphs.We hereby propose a novel algorithm, termed the differential privacy(DP) distributed push-sum based zeroth-order constrained optimization algorithm(DP-ZOCOA). Operating over time-varying unbalanced graphs, DP-ZOCOA obviates the need for supplemental suboptimization problem computations, thereby reducing overhead in comparison to distributed primary-dual methods. DP-ZOCOA is specifically tailored to tackle constrained ZOO problems over time-varying unbalanced graphs,offering a guarantee of convergence to the optimal solution while robustly preserving privacy. Moreover, we provide rigorous proofs of convergence and privacy for DP-ZOCOA, underscoring its efficacy in attaining optimal convergence without constraints. To enhance its applicability, we incorporate DP-ZOCOA into the federated learning framework and formulate a decentralized zeroth-order constrained federated learning algorithm(ZOCOA-FL) to address challenges stemming from the timevarying imbalance of communication topology. Finally, the performance and effectiveness of the proposed algorithms are thoroughly evaluated through simulations on distributed least squares(DLS) and decentralized federated learning(DFL) tasks.
基金supported in part by the National Natural Science Foundation of China(62273255,62350003,62088101)the Shanghai Science and Technology Cooperation Project(22510712000,21550760900)+1 种基金the Shanghai Municipal Science and Technology Major Project(2021SHZDZX0100)the Fundamental Research Funds for the Central Universities
文摘Dear Editor,This letter is concerned with the problem of time-varying formation tracking for heterogeneous multi-agent systems(MASs) under directed switching networks. For this purpose, our first step is to present some sufficient conditions for the exponential stability of a particular category of switched systems.
基金Supported by Key Research and Development Program of Shaanxi Province,China,No.2024SF-YBXM-078.
文摘BACKGROUND Non-suicidal self-injury(NSSI)is common among adolescents with depressive disorders and poses a major public health challenge.Rumination,a key cognitive feature of depression,includes different subtypes that may relate to NSSI through distinct psychological mechanisms.However,how these subtypes interact with specific NSSI behaviors remains unclear.AIM To examine associations between rumination subtypes and specific NSSI behaviors in adolescents.METHODS We conducted a cross-sectional study with 305 hospitalized adolescents diagnosed with depressive disorders.The subjects ranged from 12-18 years in age.Rumi-nation subtypes were assessed using the Ruminative Response Scale,and 12 NSSI behaviors were evaluated using a validated questionnaire.Network analysis was applied to explore symptom-level associations and identify central symptoms.RESULTS The network analysis revealed close connections between rumination subtypes and NSSI behaviors.Brooding was linked to behaviors such as hitting objects and burning.Scratching emerged as the most influential NSSI symptom.Symptomfocused rumination served as a key bridge connecting rumination and NSSI.CONCLUSION Symptom-focused rumination and scratching were identified as potential intervention targets.These findings highlight the psychological significance of specific cognitive-behavioral links in adolescent depression and suggest directions for tailored prevention and treatment.However,the cross-sectional,single-site design limits causal inference and generalizability.Future longitudinal and multi-center studies are needed to confirm causal pathways and verify the generalizability of the findings to broader adolescent populations.
基金supported by grants from the National Natural Science Foundation of China(82004252)the Project of Administration of Traditional Chinese Medicine of Guangdong Province(202405112017596500)the Basic and Applied Basic Research Foundation of Guangzhou Municipal Science and Technology Bureau(202102020533).
文摘Background:Wenqing Yin(WQY)is a classic prescription used to treat skin diseases like atopic dermatitis(AD)in China,and the aim of this study is to investigate the therapeutic effects and molecular mechanisms of WQY on AD.Methods:The DNFB-induced mouse models of AD were established to investigate the therapeutic effects of WQY on AD.The symptoms of AD in the ears and backs of the mice were assessed,while inflammatory factors in the ear were quantified using quantitative real-time-polymerase chain reaction(qRT-PCR),and the percentages of CD4^(+)and CD8^(+)cells in the spleen were analyzed through flow cytometry.The compounds in WQY were identified using ultra-performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS)analysis and the key targets and pathways of WQY to treat AD were predicted by network pharmacology.Subsequently,the key genes were tested and verified by qRT-PCR,and the potential active components and target proteins were verified by molecular docking.Results:WQY relieved the AD symptoms and histopathological injuries in the ear and back skin of mice with AD.Meanwhile,WQY significantly reduced the levels of inflammatory factors IL-6 and IL-1βin ear tissue,as well as the ratio of CD4^(+)/CD8^(+)cells in spleen.Additionally,a total of 142 compounds were identified from the water extract of WQY by UPLC-Orbitrap-MS/MS.39 key targets related to AD were screened out by network pharmacology methods.The KEGG analysis indicated that the effects of WQY were primarily mediated through pathways associated with Toll-like receptor signaling and T cell receptor signaling.Moreover,the results of qRT-PCR demonstrated that WQY significantly reduced the mRNA expressions of IL-4,IL-10,GATA3 and FOXP3,and molecular docking simulation verified that the active components of WQY had excellent binding abilities with IL-4,IL-10,GATA3 and FOXP3 proteins.Conclusion:The present study demonstrated that WQY effectively relieved AD symptoms in mice,decreased the inflammatory factors levels,regulated the balance of CD4^(+)and CD8^(+)cells,and the mechanism may be associated with the suppression of Th2 and Treg cell immune responses.
基金supported by Istanbul Technical University(Project No.45698)supported through the“Young Researchers’Career Development Project-training of doctoral students”of the Croatian Science Foundation.
文摘This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for identifying critical failure modes and their root causes,while BN introduces flexibility in probabilistic reasoning,enabling dynamic updates based on new evidence.This dual methodology overcomes the limitations of static FTA models,offering a comprehensive framework for system reliability analysis.Critical failures,including External Leakage(ELU),Failure to Start(FTS),and Overheating(OHE),were identified as key risks.By incorporating redundancy into high-risk components such as pumps and batteries,the likelihood of these failures was significantly reduced.For instance,redundant pumps reduced the probability of ELU by 31.88%,while additional batteries decreased the occurrence of FTS by 36.45%.The results underscore the practical benefits of combining FTA and BN for enhancing system reliability,particularly in maritime applications where operational safety and efficiency are critical.This research provides valuable insights for maintenance planning and highlights the importance of redundancy in critical systems,especially as the industry transitions toward more autonomous vessels.
文摘A new approach to damage classification for health monitoring of a time-varylng system is presented. The functional-series time-dependent auto regressive moving average （FS-TARMA） time series model is applied to the vibration signal observed in the time-varying system for estimating the TAR/TMA parameters and the innovation variance. These parameters are the functions of the time, represented by a group of projection coefficients on the certain functional subspace with specific basis functions. The estimated TAR/TMA parameters and the innovation variance are further used to calculate the latent components （LCs） as the more informative data for health monitoring evaluation, based on an eigenvalue decomposition technique. LCs are then combined and reduced to numerical values （NVs） as feature sets, which are input to a probabilistic neural network （PNN） for the damage classification. For the evaluation of the proposed method, numerical simulations of the damage classification for a tlme-varylng system are used, in which different classes of damage are modeled by the mass or stiffness reductions. It is demonstrated that the method can identify the damages in the course of operation and the change of parameters on the time-varying background of the system.
基金This work was supported by the National Key Research and Development Program of China under Grant 2018YFA0703800the National Natural Science Foundation of China under Grant 61822312This work was also supported(in part)by the Strategic Priority Research Program of Chinese Academy of Sciences under Grant No.XDA27000000.
文摘In this paper,a distributed stochastic approximation algorithm is proposed to track the dynamic root of a sum of time-varying regression functions over a network.Each agent updates its estimate by using the local observation,the dynamic information of the global root,and information received from its neighbors.Compared with similar works in optimization area,we allow the observation to be noise-corrupted,and the noise condition is much weaker.Furthermore,instead of the upper bound of the estimate error,we present the asymptotic convergence result of the algorithm.The consensus and convergence of the estimates are established.Finally,the algorithm is applied to a distributed target tracking problem and the numerical example is presented to demonstrate the performance of the algorithm.
基金supported by the National Nature Science Foundation of China(NSFC)under grant No.61771194supported by Key Program of Beijing Municipal Natural Science Foundation with No.17L20052
文摘In this work,a frame work for time-varying channel modeling and simulation is proposed by using neural network(NN)to overcome the shortcomings in geometry based stochastic model(GBSM)and simulation approach.Two NN models are developed for modeling of path loss together with shadow fading(SF)and joint small scale channel parameters.The NN models can predict path loss plus SF and small scale channel parameters accurately compared with measurement at 26 GHz performed in an outdoor microcell.The time-varying path loss and small scale channel parameters generated by the NN models are proposed to replace the empirical path loss and channel parameter random numbers in GBSM-based framework to playback the measured channel and match with its environment.Moreover,the sparse feature of clusters,delay and angular spread,channel capacity are investigated by a virtual array measurement at 28 GHz in a large waiting hall.
基金supported in part by the National Natural Science Foundation of China(61622303,61603164,61773188)the Program for Liaoning Innovative Research Team in University(LT2016006)+1 种基金the Fundamental Research Funds for the Universities of Liaoning Province(JZL201715402)the Program for Distinguished Professor of Liaoning Province
文摘Abstract--In this paper, an adaptive neural network (NN) control approach is proposed for nonlinear pure-feedback sys- tems with time-varying full state constraints. The pure-feedback systems of this paper are assumed to possess nonlinear function uncertainties. By using the mean value theorem, pure-feedback systems can be transformed into strict feedback forms. For the newly generated systems, NNs are employed to approximate unknown items. Based on the adaptive control scheme and backstepping algorithm, an intelligent controller is designed. At the same time, time-varying Barrier Lyapunov functions (BLFs) with error variables are adopted to avoid violating full state constraints in every step of the backstepping design. All closed- loop signals are uniformly ultimately bounded and the output tracking error converges to the neighborhood of zero, which can be verified by using the Lyapunov stability theorem. Two simulation examples reveal the performance of the adaptive NN control approach. Index TermsmAdaptive control, neural networks (NNs), non- linear pure-feedback systems, time-varying constraints.
基金Project supported by the National Basic Research Program of China(Grant No.2013CB328903)the Special Fund of 2011 Internet of Things Development of Ministry of Industry and Information Technology,China(Grant No.2011BAJ03B13-2)+1 种基金the National Natural Science Foundation of China(Grant No.61473050)the Key Science and Technology Program of Chongqing,China(Grant No.cstc2012gg-yyjs40008)
文摘Cascading failure can cause great damage to complex networks, so it is of great significance to improve the network robustness against cascading failure. Many previous existing works on load-redistribution strategies require global information, which is not suitable for large scale networks, and some strategies based on local information assume that the load of a node is always its initial load before the network is attacked, and the load of the failure node is redistributed to its neighbors according to their initial load or initial residual capacity. This paper proposes a new load-redistribution strategy based on local information considering an ever-changing load. It redistributes the loads of the failure node to its nearest neighbors according to their current residual capacity, which makes full use of the residual capacity of the network. Experiments are conducted on two typical networks and two real networks, and the experimental results show that the new load-redistribution strategy can reduce the size of cascading failure efficiently.
基金supported by National Natural Science Foundation of China(Nos.61290322,61273222,61322303 and 61473248)Doctoral Fund of Ministry of Education of China(No.20121333110008)+1 种基金Hebei Province Hundred Excellent Innovation Talents Support ProgramHebei Province Applied Basis Research Project(No.13961806D)
文摘This paper is concerned with the finite-time control problem for a class of networked control systems(NCSs) with short time-varying delays and sampling jitter.Considering a state feedback controller,the closed-loop NCS is described as a discrete-time linear system model,and the uncertain parts reflect the effect of the the network-induced delays and short sampling jitter of the system dynamics.Then a robust approach is proposed to solve the finite-time stability and stabilization problems for the considered NCS.An illustrative example is provided to demonstrate the effectiveness of the proposed theoretical results.
基金supported by 973 Programs (No.2008CB317110)the Key Project of Chinese Ministry of Education (No.107098)+1 种基金Sichuan Province Project for Applied Basic Research (No.2008JY0052)the Project for Academic Leader and Group of UESTC
文摘In this paper, the global exponential robust stability of neural networks with ume-varying delays is investigated. By using nonnegative matrix theory and the Halanay inequality, a new sufficient condition for global exponential robust stability is presented. It is shown that the obtained result is different from or improves some existing ones reported in the literatures. Finally, some numerical examples and a simulation are given to show the effectiveness of the obtained result.
基金supported by National Natural Science Foundation of China (No.60674027,No.60974127)Key Project of Education Ministry of China (No.208074)
文摘In this paper, the problem of the global exponential stability analysis is investigated for a class of recurrent neural networks （RNNs） with time-varying discrete and distributed delays. Due to a novel technique when estimating the upper bound of the derivative of Lyapunov functional, we establish new exponential stability criteria in terms of LMIs. It is shown that the obtained criteria can provide less conservative results than some existing ones. Numerical examples are given to show the effectiveness of the proposed results.
基金Project supported by the NBHM Research Project (Grant Nos.2/48(7)/2012/NBHM(R.P.)/R and D II/12669)
文摘In this paper, the problem of exponential synchronization of complex dynamical networks with Markovian jumping parameters using sampled-data and Mode-dependent probabilistic time-varying coupling delays is investigated. The sam- pling period is assumed to be time-varying and bounded. The information of probability distribution of the time-varying delay is considered and transformed into parameter matrices of the transferred complex dynamical network model. Based on the condition, the design method of the desired sampled data controller is proposed. By constructing a new Lyapunov functional with triple integral terms, delay-distribution-dependent exponential synchronization criteria are derived in the form of linear matrix inequalities. Finally, two numerical examples are given to illustrate the effectiveness of the proposed methods.
文摘This paper discusses H-infinity state feedback control for a networked control system with time-varying delays. Based on the flee-weighing matrix method, a dehy-dependent stability criterion satisfying a prescribed H-infinity norm bound is presented for an NCS with unknown, time-varying and bounded delays. And then, the criterion is transformed into sufficient conditions based on linear matrix inequalities for H-infinity control. The conditions thus obtained are also used to design an H-infinity state feedback controller. This design method is further extended to solve the design problem of robust H-infinity state feedback control. A numerical example demonstrates the validity of the method.
