Terahertz （THz） radiation, whose frequency ranges from 0.1 THz to 10.0 THz, has rich science, but limited technology. It has long been considered the last remaining scientific gap in the electromagnetic spectrum. Fa...Terahertz （THz） radiation, whose frequency ranges from 0.1 THz to 10.0 THz, has rich science, but limited technology. It has long been considered the last remaining scientific gap in the electromagnetic spectrum. Far from being fully exploited, it offers great opportunities in science, innovation, new technology, and potential applications. THz science and technology enables fundamental research directly impact our lives, from industrial quality control,展开更多
THz Radar Cross Section(RCS)measurement setup based on THz Time Domain Spectroscopy(TDS)is built to provide large scaled targets test ability in recent years.As calibrations,the metal plates and dihedrons are used in ...THz Radar Cross Section(RCS)measurement setup based on THz Time Domain Spectroscopy(TDS)is built to provide large scaled targets test ability in recent years.As calibrations,the metal plates and dihedrons are used in our experiments.The measurements are performed in a monostatic terahertz time-domain setup.The author proposed time domain and frequency domain calibration methods for angular RCS of calibrations,comparing the measurements with the theory to verify the ability of the time domain measurement setup.展开更多
The method of determination of elastic moduli of the geological section rocks had been developed in real conditions. The method is based on application of non-classically linearized theory of elastic waves＇ propagati...The method of determination of elastic moduli of the geological section rocks had been developed in real conditions. The method is based on application of non-classically linearized theory of elastic waves＇ propagation in the deformable media and utilization of neural networks when creating the geoseismic model. It is proposed to forecast the thin-layer model of medium by velocities of the shear waves on the base of seismic inversion of 2D profile by neural networks and geophysical well logging data. The method had been tested on materials of geophysical well logging data and 2D seismic profile related to one of the structures in the South-Caspian depression. The specific results for Poisson coefficient and elastic moduli of the third order had been obtained. The mentioned method can also be applied to forecast of other physical-mechanical properties of the medium.展开更多
There is an obvious gap in sprint level at home and abroad,and there are different opinions on the reasons.According to the analysis,physical energy and its distribution in each segment are the main factors restrictin...There is an obvious gap in sprint level at home and abroad,and there are different opinions on the reasons.According to the analysis,physical energy and its distribution in each segment are the main factors restricting the sprint performance in China.Different from middle and long-distance running,we must rely on accurate sectional timing technology to master the law of speed-physical energy change in the process of sprint.Each stage is an integral part of the whole dash process,and each part restricts each other.Each stage has a relative best achievement.Simply pursuing the optimal state of segment is not only not helpful to the final result,but also counterproductive.展开更多
The carriage rate and serotype distribution of Streptococcus pneumoniae（S.pneumoniae）in a healthy population in China remains unclear.In this study,we collected the oropharyngeal swabs from513 individuals in Xinjian...The carriage rate and serotype distribution of Streptococcus pneumoniae（S.pneumoniae）in a healthy population in China remains unclear.In this study,we collected the oropharyngeal swabs from513 individuals in Xinjiang,China.Real-time PCR targeting the lytA gene and 12 serotypes were assessed to identify S.pneumoniae carriage.展开更多
Dynamics of the Au + H2 reaction are studied using time-dependent wave packet(TDWP) and quasi-classical trajectory(QCT) methods based on a new potential energy surface [Int. J. Quantum Chem. 118 e25493(2018)]. The dyn...Dynamics of the Au + H2 reaction are studied using time-dependent wave packet(TDWP) and quasi-classical trajectory(QCT) methods based on a new potential energy surface [Int. J. Quantum Chem. 118 e25493(2018)]. The dynamic properties such as reaction probability, integral cross section, differential cross section and the distribution of product are studied at state-to-state level of theory. Furthermore, the present results are compared with the theoretical studies available.The results indicate that the complex-forming reaction mechanism is dominated in the reaction in the low collision energy region and the abstract reaction mechanism plays a dominant role at high collision energies. Different from previous theoretical calculations, the side-ways scattering signals are found in the present work and become more and more apparent with increasing collision energy.展开更多
A finite-different time-domain （FDTD） algorithm is applied in this paper to study the bistatic electromagnetic（EM） scattering by a conductive cylinder covered with inhomogeneous, collision, cold, time-varying plas...A finite-different time-domain （FDTD） algorithm is applied in this paper to study the bistatic electromagnetic（EM） scattering by a conductive cylinder covered with inhomogeneous, collision, cold, time-varying plasma. The collision frequency of plasma is a function of the electron density and the pressure of the background gas. The plasma density follows any prescribed distribution function of the rise time of plasma and the radius of the column. The bistatic radar cross section （RCS） of the conductive cylinder covered with inhomogeneous time-varying plasma and inhomogeneous steady-state plasma is calculated under different conditions. The results illustrate that a plasma cloaking system can successfully reduce the RCS of the conductive cylinder.展开更多
Several major challenges need to be faced for efficient transient multiscale electromagnetic simulations, such as flex- ible and robust geometric modeling schemes, efficient and stable time-stepping algorithms, etc. F...Several major challenges need to be faced for efficient transient multiscale electromagnetic simulations, such as flex- ible and robust geometric modeling schemes, efficient and stable time-stepping algorithms, etc. Fortunately, because of the versatile choices of spatial discretization and temporal integration, a discontinuous Galerkin time-domain （DGTD） method can be a very promising method of solving transient multiscale electromagnetic problems. In this paper, we present the application of a leap-frog DGTD method to the analyzing of the multiscale electromagnetic scattering problems. The uniaxial perfect matching layer （UPML） truncation of the computational domain is discussed and formulated in the leap-frog DGTD context. Numerical validations are performed in the challenging test cases demonstrating the accuracy and effectiveness of the method in solving transient multiscale electromagnetic problems compared with those of other numerical methods.展开更多
A conformal multi-resolution time-domain( CMRTD) method is presented for modeling curved objects. The effective dielectric constant and area weighting are used to derive the update equations of CMRTD. The backward sca...A conformal multi-resolution time-domain( CMRTD) method is presented for modeling curved objects. The effective dielectric constant and area weighting are used to derive the update equations of CMRTD. The backward scattering bistatic radar cross sections( RCS) of the dielectric cylinder and ellipsoid are used to validate the proposed method. The results show that the proposed conformal method is more accurate to deal with the complex curved objects in electromagnetic simulations.展开更多
Radar Cross Section (RCS) is one of the most considerable parameters for ship stealth design. As modern ships are larger than their predecessors, RCS must be managed at each design stage for its reduction. For predict...Radar Cross Section (RCS) is one of the most considerable parameters for ship stealth design. As modern ships are larger than their predecessors, RCS must be managed at each design stage for its reduction. For predicting RCS of ship, Radar Cross Section Analysis Program (RACSAN) based on Kirchhoff approximation in high frequency range has been developed. This program can present RCS including multi-bounce effect in exterior and interior structure by combination of geometric optics (GO) and physical optics (PO) methods, coating effect by using Fresnel reflection coefficient, and response time pattern for detected target. In this paper, RCS calculations of ship model with above effects are simulated by using this developed program and RCS results are discussed.展开更多
A Neutron Time-of-Flight(NTOF) spectrometer, based at the Heavy Ion Research Facility in Lanzhou(HIRFL) was developed for studies of neutron production of proton induced spallation reactions related to the ADS project...A Neutron Time-of-Flight(NTOF) spectrometer, based at the Heavy Ion Research Facility in Lanzhou(HIRFL) was developed for studies of neutron production of proton induced spallation reactions related to the ADS project. After the presentation of comparisons between calculated spallation neutron production doubledifferential cross sections and the available experimental data, a detailed description of the NTOF spectrometer is given. Test beam results show that the spectrometer works well and data analysis procedures are established.The comparisons of the test beam neutron spectra with those of GEANT4 simulations are presented.展开更多
Background: Protein kinase B (AKT/PKB) family is frequently amplified in ovarian cancer (OC). To the greatest of our knowledge, there is a lack of published reports about the amplification of the genes belonging to th...Background: Protein kinase B (AKT/PKB) family is frequently amplified in ovarian cancer (OC). To the greatest of our knowledge, there is a lack of published reports about the amplification of the genes belonging to the AKT family among Sudanese women with OC. The present study was conducted to detect the AKT1 gene amplification and its association with tumour types, grades, and ages among Sudanese women with OC, bearing in mind the ethnic variation. Methods: This institution-based study included 79 cases of women diagnosed with ovarian cancer (OC) at Omdurman Maternity Hospital in the period 2013-2018. Formalin-fixed, paraffin-embedded (FFPE) tissue sections were used to extract RNA. AKT1 gene amplification was assessed using quantitative real-time PCR. Results: The mean age (±SD) of included women was 49.29 (±13.612). The amplification of AKT1 gene was observed in 18/79 (22.8%) of OC women, with a high frequency in women with undifferentiated 1/2 (50%), clear cell 2/6 (33.3%), mucinous 3/11 (27.3%), endometrioid 3/17 (17.6%), and serous carcinomas 5/30 OC (16.7%). High frequency was seen in women with low (26.3%;n = 10/28) rather than in higher (19.5%;n = 8/33) grade carcinoma, and in older (25.8%;n = 8/23) rather than younger (18.2%;n = 2/9) women. No significant association between AKT1 gene amplification and tumour types, grades, and ages of women was observed (Fisher’s Exact test: p = 0.405, 0.593 and 0.851, respectively). Conclusion: AKT1 gene amplification arises in around one-fifth of Sudanese women with ovarian cancer (OC). It is seen more in undifferentiated, clear cell, and mucinous tumours types, and more frequently in low tumour grade and older women, but not to a statistically significant level. These outcomes sustenance previous studies suggesting that activated AKT genes have a vital role in OC progression and may offer a plan for targeted therapy and prognostic evaluation.展开更多
目的探讨维持性血液透析(maintenance hemodialysis,MHD)患者计时站立行走测试(time up and go test,TUG)时间延长的影响因素。方法采用横断面调查法,选取2023年6月1日至2024年1月31日于首都医科大学附属北京潞河医院规律血液透析、数...目的探讨维持性血液透析(maintenance hemodialysis,MHD)患者计时站立行走测试(time up and go test,TUG)时间延长的影响因素。方法采用横断面调查法,选取2023年6月1日至2024年1月31日于首都医科大学附属北京潞河医院规律血液透析、数据完整且可配合的患者,分别采用简易精神状态检查表(Minimum Mental State Examination,MMSE)、5次起坐试验(5 times sit to stand,STS-5)、TUG量表评估患者认知功能、下肢肌肉力量、平衡及步态功能;根据TUG结果进行分组,即TUG≤12 s,判定为TUG正常组;TUG>12 s判定为TUG延长组,采用多因素Logistic回归法分析患者TUG延长组的影响因素,以受试者工作特征(receiver operating characteristic,ROC)曲线分析影响因素对TUG延长患者的预测价值。结果本研究共纳入146例MHD患者,TUG延长组86例,TUG正常组60例,两组的性别、年龄、合并高血压、合并糖尿病、血糖、教育水平、MMSE评分、C反应蛋白、血白蛋白、血肌酐、血钠、全段甲状旁腺素、低密度脂蛋白胆固醇、血尿酸、STS-5、单次尿素氮清除指数(urea clearance index,Kt/V)差异具有统计学意义(P<0.05);进一步行多因素Logistic回归分析显示,高龄、女性、低MMSE评分、低Kt/V以及STS-5时间延长是发生TUG延长的独立危险因素(P<0.05);ROC曲线显示,年龄、性别、MMSE总分、STS-5时间预测MHD患者发生TUG延长的曲线下面积(area under the curve,AUC)分别为0.825、0.678、0.777、0.836(P<0.01),具有较高的预测价值,Kt/V预测患者发生TUG延长的AUC为0.602(P=0.037),有一定的预测价值;以上5项指标作为整体模型预测MHD患者发生TUG延长的AUC为0.923(P<0.01)结论MHD患者的年龄、性别、MMSE评分、STS-5时间延长、Kt/V的水平与合并TUG延长相关,是发生TUG延长的独立危险因素,可能成为预测TUG延长的生物学指标。展开更多
文摘Terahertz （THz） radiation, whose frequency ranges from 0.1 THz to 10.0 THz, has rich science, but limited technology. It has long been considered the last remaining scientific gap in the electromagnetic spectrum. Far from being fully exploited, it offers great opportunities in science, innovation, new technology, and potential applications. THz science and technology enables fundamental research directly impact our lives, from industrial quality control,
基金The Science and Technology Commission of Shanghai Municipality under Grant(16ZR1435000)
文摘THz Radar Cross Section(RCS)measurement setup based on THz Time Domain Spectroscopy(TDS)is built to provide large scaled targets test ability in recent years.As calibrations,the metal plates and dihedrons are used in our experiments.The measurements are performed in a monostatic terahertz time-domain setup.The author proposed time domain and frequency domain calibration methods for angular RCS of calibrations,comparing the measurements with the theory to verify the ability of the time domain measurement setup.
文摘The method of determination of elastic moduli of the geological section rocks had been developed in real conditions. The method is based on application of non-classically linearized theory of elastic waves＇ propagation in the deformable media and utilization of neural networks when creating the geoseismic model. It is proposed to forecast the thin-layer model of medium by velocities of the shear waves on the base of seismic inversion of 2D profile by neural networks and geophysical well logging data. The method had been tested on materials of geophysical well logging data and 2D seismic profile related to one of the structures in the South-Caspian depression. The specific results for Poisson coefficient and elastic moduli of the third order had been obtained. The mentioned method can also be applied to forecast of other physical-mechanical properties of the medium.
文摘There is an obvious gap in sprint level at home and abroad,and there are different opinions on the reasons.According to the analysis,physical energy and its distribution in each segment are the main factors restricting the sprint performance in China.Different from middle and long-distance running,we must rely on accurate sectional timing technology to master the law of speed-physical energy change in the process of sprint.Each stage is an integral part of the whole dash process,and each part restricts each other.Each stage has a relative best achievement.Simply pursuing the optimal state of segment is not only not helpful to the final result,but also counterproductive.
基金supported by grants from the State Key Laboratory of Infectious Disease Prevention and Control[2015SKLID502]the National Natural Science Foundation of China[81602903]Youth Science and Technology Talented Project of special scientific research in health and family planning commission in Xinjiang Uygur Autonomous Region[2016Y25]
文摘The carriage rate and serotype distribution of Streptococcus pneumoniae（S.pneumoniae）in a healthy population in China remains unclear.In this study,we collected the oropharyngeal swabs from513 individuals in Xinjiang,China.Real-time PCR targeting the lytA gene and 12 serotypes were assessed to identify S.pneumoniae carriage.
文摘Dynamics of the Au + H2 reaction are studied using time-dependent wave packet(TDWP) and quasi-classical trajectory(QCT) methods based on a new potential energy surface [Int. J. Quantum Chem. 118 e25493(2018)]. The dynamic properties such as reaction probability, integral cross section, differential cross section and the distribution of product are studied at state-to-state level of theory. Furthermore, the present results are compared with the theoretical studies available.The results indicate that the complex-forming reaction mechanism is dominated in the reaction in the low collision energy region and the abstract reaction mechanism plays a dominant role at high collision energies. Different from previous theoretical calculations, the side-ways scattering signals are found in the present work and become more and more apparent with increasing collision energy.
基金supported by National Natural Science Foundation of China (No. 60471002)the Natural Science Foundation of Jiangxi Province (No. 0412014)
文摘A finite-different time-domain （FDTD） algorithm is applied in this paper to study the bistatic electromagnetic（EM） scattering by a conductive cylinder covered with inhomogeneous, collision, cold, time-varying plasma. The collision frequency of plasma is a function of the electron density and the pressure of the background gas. The plasma density follows any prescribed distribution function of the rise time of plasma and the radius of the column. The bistatic radar cross section （RCS） of the conductive cylinder covered with inhomogeneous time-varying plasma and inhomogeneous steady-state plasma is calculated under different conditions. The results illustrate that a plasma cloaking system can successfully reduce the RCS of the conductive cylinder.
基金supported by the National Natural Science Foundation of China(Grant Nos.61301056 and 11176007)the Sichuan Provincial Science and Technology Support Program,China(Grant No.2013HH0047)+1 种基金the Fok Ying Tung Education Foundation,China(Grant No.141062)the"111"Project,China(Grant No.B07046)
文摘Several major challenges need to be faced for efficient transient multiscale electromagnetic simulations, such as flex- ible and robust geometric modeling schemes, efficient and stable time-stepping algorithms, etc. Fortunately, because of the versatile choices of spatial discretization and temporal integration, a discontinuous Galerkin time-domain （DGTD） method can be a very promising method of solving transient multiscale electromagnetic problems. In this paper, we present the application of a leap-frog DGTD method to the analyzing of the multiscale electromagnetic scattering problems. The uniaxial perfect matching layer （UPML） truncation of the computational domain is discussed and formulated in the leap-frog DGTD context. Numerical validations are performed in the challenging test cases demonstrating the accuracy and effectiveness of the method in solving transient multiscale electromagnetic problems compared with those of other numerical methods.
基金Supported by the National Natural Science Foundation of China(61172024)the Funding of Jiangsu Innovation Program for Graduate Education and the Fundamental Research Funds for the Central Universities(CXZZ12-0156)
文摘A conformal multi-resolution time-domain( CMRTD) method is presented for modeling curved objects. The effective dielectric constant and area weighting are used to derive the update equations of CMRTD. The backward scattering bistatic radar cross sections( RCS) of the dielectric cylinder and ellipsoid are used to validate the proposed method. The results show that the proposed conformal method is more accurate to deal with the complex curved objects in electromagnetic simulations.
文摘Radar Cross Section (RCS) is one of the most considerable parameters for ship stealth design. As modern ships are larger than their predecessors, RCS must be managed at each design stage for its reduction. For predicting RCS of ship, Radar Cross Section Analysis Program (RACSAN) based on Kirchhoff approximation in high frequency range has been developed. This program can present RCS including multi-bounce effect in exterior and interior structure by combination of geometric optics (GO) and physical optics (PO) methods, coating effect by using Fresnel reflection coefficient, and response time pattern for detected target. In this paper, RCS calculations of ship model with above effects are simulated by using this developed program and RCS results are discussed.
基金Supported by National Natural Science Foundation of China(No.11075189)100 Persons Project(Nos.0910020BR0 and Y010110BR0)ADS Project 302 of the Chinese Academy of Sciences(No.XDA03030200)
文摘A Neutron Time-of-Flight(NTOF) spectrometer, based at the Heavy Ion Research Facility in Lanzhou(HIRFL) was developed for studies of neutron production of proton induced spallation reactions related to the ADS project. After the presentation of comparisons between calculated spallation neutron production doubledifferential cross sections and the available experimental data, a detailed description of the NTOF spectrometer is given. Test beam results show that the spectrometer works well and data analysis procedures are established.The comparisons of the test beam neutron spectra with those of GEANT4 simulations are presented.
文摘Background: Protein kinase B (AKT/PKB) family is frequently amplified in ovarian cancer (OC). To the greatest of our knowledge, there is a lack of published reports about the amplification of the genes belonging to the AKT family among Sudanese women with OC. The present study was conducted to detect the AKT1 gene amplification and its association with tumour types, grades, and ages among Sudanese women with OC, bearing in mind the ethnic variation. Methods: This institution-based study included 79 cases of women diagnosed with ovarian cancer (OC) at Omdurman Maternity Hospital in the period 2013-2018. Formalin-fixed, paraffin-embedded (FFPE) tissue sections were used to extract RNA. AKT1 gene amplification was assessed using quantitative real-time PCR. Results: The mean age (±SD) of included women was 49.29 (±13.612). The amplification of AKT1 gene was observed in 18/79 (22.8%) of OC women, with a high frequency in women with undifferentiated 1/2 (50%), clear cell 2/6 (33.3%), mucinous 3/11 (27.3%), endometrioid 3/17 (17.6%), and serous carcinomas 5/30 OC (16.7%). High frequency was seen in women with low (26.3%;n = 10/28) rather than in higher (19.5%;n = 8/33) grade carcinoma, and in older (25.8%;n = 8/23) rather than younger (18.2%;n = 2/9) women. No significant association between AKT1 gene amplification and tumour types, grades, and ages of women was observed (Fisher’s Exact test: p = 0.405, 0.593 and 0.851, respectively). Conclusion: AKT1 gene amplification arises in around one-fifth of Sudanese women with ovarian cancer (OC). It is seen more in undifferentiated, clear cell, and mucinous tumours types, and more frequently in low tumour grade and older women, but not to a statistically significant level. These outcomes sustenance previous studies suggesting that activated AKT genes have a vital role in OC progression and may offer a plan for targeted therapy and prognostic evaluation.
文摘目的探讨维持性血液透析(maintenance hemodialysis,MHD)患者计时站立行走测试(time up and go test,TUG)时间延长的影响因素。方法采用横断面调查法,选取2023年6月1日至2024年1月31日于首都医科大学附属北京潞河医院规律血液透析、数据完整且可配合的患者,分别采用简易精神状态检查表(Minimum Mental State Examination,MMSE)、5次起坐试验(5 times sit to stand,STS-5)、TUG量表评估患者认知功能、下肢肌肉力量、平衡及步态功能;根据TUG结果进行分组,即TUG≤12 s,判定为TUG正常组;TUG>12 s判定为TUG延长组,采用多因素Logistic回归法分析患者TUG延长组的影响因素,以受试者工作特征(receiver operating characteristic,ROC)曲线分析影响因素对TUG延长患者的预测价值。结果本研究共纳入146例MHD患者,TUG延长组86例,TUG正常组60例,两组的性别、年龄、合并高血压、合并糖尿病、血糖、教育水平、MMSE评分、C反应蛋白、血白蛋白、血肌酐、血钠、全段甲状旁腺素、低密度脂蛋白胆固醇、血尿酸、STS-5、单次尿素氮清除指数(urea clearance index,Kt/V)差异具有统计学意义(P<0.05);进一步行多因素Logistic回归分析显示,高龄、女性、低MMSE评分、低Kt/V以及STS-5时间延长是发生TUG延长的独立危险因素(P<0.05);ROC曲线显示,年龄、性别、MMSE总分、STS-5时间预测MHD患者发生TUG延长的曲线下面积(area under the curve,AUC)分别为0.825、0.678、0.777、0.836(P<0.01),具有较高的预测价值,Kt/V预测患者发生TUG延长的AUC为0.602(P=0.037),有一定的预测价值;以上5项指标作为整体模型预测MHD患者发生TUG延长的AUC为0.923(P<0.01)结论MHD患者的年龄、性别、MMSE评分、STS-5时间延长、Kt/V的水平与合并TUG延长相关,是发生TUG延长的独立危险因素,可能成为预测TUG延长的生物学指标。
