Chronic hepatitis B infection is a major health problem,with approximately 350 million virus carriers worldwide.In Africa,about 30%-60%of children and 60%-100%of adults have been infected with hepatitis B virus(HBV).P...Chronic hepatitis B infection is a major health problem,with approximately 350 million virus carriers worldwide.In Africa,about 30%-60%of children and 60%-100%of adults have been infected with hepatitis B virus(HBV).Persistent infection with HBV can lead to cirrhosis and primary hepatocellular carcinoma.Mathematical models are a useful tool to forecast the future development of diseases.In 1981,Capasso and Maddalena proposed and analyzed a reaction diffusion system modeling the spatial spread of a class of bacterial and viral diseases.展开更多
基金supported by the National Natural Science Foundationof China,No.60774036the NSF of Hubei Province 2008CDA063
文摘Chronic hepatitis B infection is a major health problem,with approximately 350 million virus carriers worldwide.In Africa,about 30%-60%of children and 60%-100%of adults have been infected with hepatitis B virus(HBV).Persistent infection with HBV can lead to cirrhosis and primary hepatocellular carcinoma.Mathematical models are a useful tool to forecast the future development of diseases.In 1981,Capasso and Maddalena proposed and analyzed a reaction diffusion system modeling the spatial spread of a class of bacterial and viral diseases.