Objective: Report a rare case of a thyroid papillary carcinoma situated within a branchial cleft cyst. Case presentation: A 40-year-old male was referred to our department for a lateral neck mass assessment. Physical ...Objective: Report a rare case of a thyroid papillary carcinoma situated within a branchial cleft cyst. Case presentation: A 40-year-old male was referred to our department for a lateral neck mass assessment. Physical examination revealed a solitary palpable, painless, moveable neck mass. Assessment included complete nasal, pharynx and larynx endoscopy, neck computed tomography, and fine needle aspiration biopsy. Treatment was surgical excision of the neck mass. Histopathology confirmed a branchial cleft cyst with papillary thyroid carcinoma growth at a site. A neck and thyroid ultrasound showed presence of thyroid gland nodules (one of which with micro calcifications). Thyroid fine needle aspiration biopsy performed, was high suspicious for malignancy (BETHESDA V). Patient underwent total thyroidectomy and histopathology revealed papillary thyroid carcinoma. Conclusion: Although rarely, it is possible to face an unexpected malignancy within a clinically benign neck lesion. A thorough diagnostic work-up enables early identification of aforementioned potential malignancy. A diagnostic dilemma that arises in such cases is between primary or metastatic disease and a thyroid carcinoma arising from ectopic thyroid tissue.展开更多
目的 ：探讨超声引导下注射硬化剂聚桂醇治疗甲状腺囊肿的临床疗效及安全性。方法 ：采用超声引导经皮穿刺囊腔内注射聚桂醇,治疗甲状腺囊肿共78例。治疗前所有囊肿均接受甲状腺穿刺及细胞病理学检查,以排除恶性病变。治疗时尽量将囊液...目的 ：探讨超声引导下注射硬化剂聚桂醇治疗甲状腺囊肿的临床疗效及安全性。方法 ：采用超声引导经皮穿刺囊腔内注射聚桂醇,治疗甲状腺囊肿共78例。治疗前所有囊肿均接受甲状腺穿刺及细胞病理学检查,以排除恶性病变。治疗时尽量将囊液抽吸净,然后注入约1/3囊腔容积量的聚桂醇进行硬化治疗,每周1次,根据囊肿的缩小情况,共治疗1-4次。结果：178例囊肿共进行166次硬化治疗,3个月后囊肿容积平均缩小71.6%±35.3%,与治疗前相比有显著差异（P〈0.01）;治疗总有效率84.6%（66/78）,治愈率52.6%（41/78）;2不同容积大小的囊肿治愈率有统计学差异（P〈0.01）,容积〉5 m L的囊肿治愈率显著高于容积〈5 m L者（P〈0.01）,但不同容积囊肿的治疗有效率无统计学差异（P〉0.05）;3治疗前后患者甲状腺功能及甲状腺相关抗体滴度无显著变化;4治疗的并发症发生率低,无严重不良反应。结论：超声引导下注射聚桂醇治疗甲状腺囊性病变简单易行、临床效果好,不良反应少,可作为甲状腺囊肿的首选治疗方法之一。展开更多
文摘Objective: Report a rare case of a thyroid papillary carcinoma situated within a branchial cleft cyst. Case presentation: A 40-year-old male was referred to our department for a lateral neck mass assessment. Physical examination revealed a solitary palpable, painless, moveable neck mass. Assessment included complete nasal, pharynx and larynx endoscopy, neck computed tomography, and fine needle aspiration biopsy. Treatment was surgical excision of the neck mass. Histopathology confirmed a branchial cleft cyst with papillary thyroid carcinoma growth at a site. A neck and thyroid ultrasound showed presence of thyroid gland nodules (one of which with micro calcifications). Thyroid fine needle aspiration biopsy performed, was high suspicious for malignancy (BETHESDA V). Patient underwent total thyroidectomy and histopathology revealed papillary thyroid carcinoma. Conclusion: Although rarely, it is possible to face an unexpected malignancy within a clinically benign neck lesion. A thorough diagnostic work-up enables early identification of aforementioned potential malignancy. A diagnostic dilemma that arises in such cases is between primary or metastatic disease and a thyroid carcinoma arising from ectopic thyroid tissue.
文摘目的 ：探讨超声引导下注射硬化剂聚桂醇治疗甲状腺囊肿的临床疗效及安全性。方法 ：采用超声引导经皮穿刺囊腔内注射聚桂醇,治疗甲状腺囊肿共78例。治疗前所有囊肿均接受甲状腺穿刺及细胞病理学检查,以排除恶性病变。治疗时尽量将囊液抽吸净,然后注入约1/3囊腔容积量的聚桂醇进行硬化治疗,每周1次,根据囊肿的缩小情况,共治疗1-4次。结果：178例囊肿共进行166次硬化治疗,3个月后囊肿容积平均缩小71.6%±35.3%,与治疗前相比有显著差异（P〈0.01）;治疗总有效率84.6%（66/78）,治愈率52.6%（41/78）;2不同容积大小的囊肿治愈率有统计学差异（P〈0.01）,容积〉5 m L的囊肿治愈率显著高于容积〈5 m L者（P〈0.01）,但不同容积囊肿的治疗有效率无统计学差异（P〉0.05）;3治疗前后患者甲状腺功能及甲状腺相关抗体滴度无显著变化;4治疗的并发症发生率低,无严重不良反应。结论：超声引导下注射聚桂醇治疗甲状腺囊性病变简单易行、临床效果好,不良反应少,可作为甲状腺囊肿的首选治疗方法之一。
