Objective To observe the effects of thumbtackneedle embedding therapy of auricular acupuncture on gastrointestinal function and intestinal microflora in the patients with gastric cancer after operation,and to explore ...Objective To observe the effects of thumbtackneedle embedding therapy of auricular acupuncture on gastrointestinal function and intestinal microflora in the patients with gastric cancer after operation,and to explore its mechanism.Methods A total of 80 patients with gastric cancer after radical operation were randomly divided into an observation group(40 cases,3 cases discontinued)and a control group(40 cases,3 cases discontinued).The patients of both groups received the perioperative care for accelerating recovery.Additionally,in the observation group,the thumbtack-needle embedding therapy of auricular acupuncture was delivered at the auricular points of unilateral side,including Wei(CO4),Pi(COis),Dachang(CO,),Xiaochang(CO。),Yuanzhong(AT2,3,4i),Erzhong(HX,),Sanjiao(COiz)and Jiaowozhong(TF,),and the needles were embedded and retained for 72 h.The postoperative recovery time of gastrointestinal function(the postoperative bowel sound recovery time,the first exhaust time,the first defecation time),the postoperative hospital stay and pain visual analogue scale(VAS)score were observed in the two groups.Before operation and on day 5 after operation,the serum gastrin level was detected in the two groups.The third-generation 16S rRNA sequencing technology was used to detect the composition and relative abundance of intestinal flora in the two groups before and after operation.Results Compared with the control group,the postoperative bowel sound recovery time,the first exhaust time and the first defecation time were shortened in the observation group(P<0.05).In the observation group,the VAS scores at 24 h,48 h,and 72 h after surgery were lower than those of the control group,respectively(P<0.05).There was no significant differences in postoperative hospital stay and serum gastrin level between the two groups(P>0.05).The alpha diversity analysis showed that the differences in Shannon index,Simpson index,Pielou_J index and Pd_fath index were not significant statisticallyyafter intervention between the two groups(P>0.05).After intervention,the community structure of the fecal sample was similar at each taxonomic level between the two groups,and although the proportion between species was various,the difference was not significant(P>0.05).After intervention,there were 55 species with the differences between the two groups,17 species of them presented significant difference in relative abundance in the observation group and 38 species in the control group.Regarding the level of genus,the levels of Klebsiell and Enterobacter increased(P<0.05)and the level of Streptococcus decreased(P<0.05)in the observation group.The main microbial groups that played an important role were Coprobacillaceae,Sutterellaceae and Yersiniaceae in the observation group.KEGG functionprediction indicated that the function of intestinal microfloraa was mainly associated with the cofactor and vitamin metabolism,carbohydrate metabolism,and amino acid metabolism.Conclusion The thumbtackneedle embedding therapy of auricular acupuncture improves the postoperative gastrointestinal function of the patients with gastric cancer probably through regulating the structure and relative abundance of intestinal microflora and affecting the energy metabolism.展开更多
The paper reports a successful case of unilateral oculomotor palsy treated with acupuncture in a Chinese boy aged 5 years and 3 months.Filiform needles were applied for ptosis,ocular motility impairment and blurred vi...The paper reports a successful case of unilateral oculomotor palsy treated with acupuncture in a Chinese boy aged 5 years and 3 months.Filiform needles were applied for ptosis,ocular motility impairment and blurred vision of the left oculomotor palsy after arachnoid cyst surgery.Two stages of treatment with acupuncture were composed.Acupuncture in the first stage focused on resolving stasis,unblocking meridians and activating qi and blood circulation,especially at the acupoints around the eye,combined with the distal points(four gate points)to enhance qi movement and activate blood circulation,once daily.Besides,the western medicines for nerve nutrition were added.One month later,all the symptoms were alleviated,and the eyelid could be lifted.Then,the second stage of acupuncture started,during which,the western medicine for nerve nutrition was withdrawal,acupuncture was continued with the same acupoints as the first stage,once every two days.Besides,the thumb-tack needle was used to maintain the effect of filiform needle,and Zusanli(ST36)was added to replenish qi of spleen and stomach and promote circulation of meridians.Another month later,the lift of the left eyelid and the ocular motility were basically symmetrical to the right eye,and the left eye vision returned normal.Follow-up until the time of publication,the motility and function of the affected eye were basically the same as those of the healthy side.This case suggests that the staged intervention with acupuncture could be effective in child with unilateral oculomotor palsy after arachnoid cyst surgery and were acceptable for child.Further studies are needed to confirm the effect and mechanism of acupuncture intervention on postoperative oculomotor palsy.展开更多
In view of the serious threat to people's health caused by the Coronavirus Disease 2019(COVID-19),according to the relevant spirit of the Notice on Establishing the Cooperation Mechanism of traditional Chinese and...In view of the serious threat to people's health caused by the Coronavirus Disease 2019(COVID-19),according to the relevant spirit of the Notice on Establishing the Cooperation Mechanism of traditional Chinese and Western Medicine in the Prevention and Treatment of COVID-19 and other Infectious Diseases issued by the National Health Commission of the People's Republic of China,National Administration of Traditional Chinese Medicine of the People's Republic of China,on the basis of our early clinical research of using press needle embedding(intradermal acupuncture)to prevent and treat related diseases,the symptoms,etiology and pathogenesis of the disease were analyzed.We try to use the simple and easy intradermal acupuncture therapy to prevent and assist the treatment of the disease and its complications,hoping to make a modest contribution to help patients relieve part of suffering,and also provide advice for the doctors in the treatment of the disease.展开更多
文摘Objective To observe the effects of thumbtackneedle embedding therapy of auricular acupuncture on gastrointestinal function and intestinal microflora in the patients with gastric cancer after operation,and to explore its mechanism.Methods A total of 80 patients with gastric cancer after radical operation were randomly divided into an observation group(40 cases,3 cases discontinued)and a control group(40 cases,3 cases discontinued).The patients of both groups received the perioperative care for accelerating recovery.Additionally,in the observation group,the thumbtack-needle embedding therapy of auricular acupuncture was delivered at the auricular points of unilateral side,including Wei(CO4),Pi(COis),Dachang(CO,),Xiaochang(CO。),Yuanzhong(AT2,3,4i),Erzhong(HX,),Sanjiao(COiz)and Jiaowozhong(TF,),and the needles were embedded and retained for 72 h.The postoperative recovery time of gastrointestinal function(the postoperative bowel sound recovery time,the first exhaust time,the first defecation time),the postoperative hospital stay and pain visual analogue scale(VAS)score were observed in the two groups.Before operation and on day 5 after operation,the serum gastrin level was detected in the two groups.The third-generation 16S rRNA sequencing technology was used to detect the composition and relative abundance of intestinal flora in the two groups before and after operation.Results Compared with the control group,the postoperative bowel sound recovery time,the first exhaust time and the first defecation time were shortened in the observation group(P<0.05).In the observation group,the VAS scores at 24 h,48 h,and 72 h after surgery were lower than those of the control group,respectively(P<0.05).There was no significant differences in postoperative hospital stay and serum gastrin level between the two groups(P>0.05).The alpha diversity analysis showed that the differences in Shannon index,Simpson index,Pielou_J index and Pd_fath index were not significant statisticallyyafter intervention between the two groups(P>0.05).After intervention,the community structure of the fecal sample was similar at each taxonomic level between the two groups,and although the proportion between species was various,the difference was not significant(P>0.05).After intervention,there were 55 species with the differences between the two groups,17 species of them presented significant difference in relative abundance in the observation group and 38 species in the control group.Regarding the level of genus,the levels of Klebsiell and Enterobacter increased(P<0.05)and the level of Streptococcus decreased(P<0.05)in the observation group.The main microbial groups that played an important role were Coprobacillaceae,Sutterellaceae and Yersiniaceae in the observation group.KEGG functionprediction indicated that the function of intestinal microfloraa was mainly associated with the cofactor and vitamin metabolism,carbohydrate metabolism,and amino acid metabolism.Conclusion The thumbtackneedle embedding therapy of auricular acupuncture improves the postoperative gastrointestinal function of the patients with gastric cancer probably through regulating the structure and relative abundance of intestinal microflora and affecting the energy metabolism.
基金Supported by Shanghai municipality to further accelerated the three-year action plan for the development of Traditional Chinese Medicine project funding:ZY(2018-2020)-ZYBZ-17。
文摘The paper reports a successful case of unilateral oculomotor palsy treated with acupuncture in a Chinese boy aged 5 years and 3 months.Filiform needles were applied for ptosis,ocular motility impairment and blurred vision of the left oculomotor palsy after arachnoid cyst surgery.Two stages of treatment with acupuncture were composed.Acupuncture in the first stage focused on resolving stasis,unblocking meridians and activating qi and blood circulation,especially at the acupoints around the eye,combined with the distal points(four gate points)to enhance qi movement and activate blood circulation,once daily.Besides,the western medicines for nerve nutrition were added.One month later,all the symptoms were alleviated,and the eyelid could be lifted.Then,the second stage of acupuncture started,during which,the western medicine for nerve nutrition was withdrawal,acupuncture was continued with the same acupoints as the first stage,once every two days.Besides,the thumb-tack needle was used to maintain the effect of filiform needle,and Zusanli(ST36)was added to replenish qi of spleen and stomach and promote circulation of meridians.Another month later,the lift of the left eyelid and the ocular motility were basically symmetrical to the right eye,and the left eye vision returned normal.Follow-up until the time of publication,the motility and function of the affected eye were basically the same as those of the healthy side.This case suggests that the staged intervention with acupuncture could be effective in child with unilateral oculomotor palsy after arachnoid cyst surgery and were acceptable for child.Further studies are needed to confirm the effect and mechanism of acupuncture intervention on postoperative oculomotor palsy.
基金Supported by 2011 Special Projects in Scientific Research of TCM Profession(201107006)2018 Preventive Treatment of Disease in Tianjin University of Traditional Chinese Medicine(XJ201801)。
文摘In view of the serious threat to people's health caused by the Coronavirus Disease 2019(COVID-19),according to the relevant spirit of the Notice on Establishing the Cooperation Mechanism of traditional Chinese and Western Medicine in the Prevention and Treatment of COVID-19 and other Infectious Diseases issued by the National Health Commission of the People's Republic of China,National Administration of Traditional Chinese Medicine of the People's Republic of China,on the basis of our early clinical research of using press needle embedding(intradermal acupuncture)to prevent and treat related diseases,the symptoms,etiology and pathogenesis of the disease were analyzed.We try to use the simple and easy intradermal acupuncture therapy to prevent and assist the treatment of the disease and its complications,hoping to make a modest contribution to help patients relieve part of suffering,and also provide advice for the doctors in the treatment of the disease.
