Objective： To evaluate the efficacy and safety of ＂Three-Typed Syndrome Differentiation＂ （I-TSD） in treating type 2 diabetes mellitus patients. Methods： A systematic review and meta-analysis was done based on th...Objective： To evaluate the efficacy and safety of ＂Three-Typed Syndrome Differentiation＂ （I-TSD） in treating type 2 diabetes mellitus patients. Methods： A systematic review and meta-analysis was done based on the clinical diabetes treatment literature of the ＂I-I＇SD＂. Overseas databases like the PubMed/MEDLINE, EMBASE, Cochrane Library and Cochrane Central Register of Controlled Clinical Trials, and China databases like China Biology Medicine Disc （CBM）, Chinese national Knowledge Infrastructure （CNKI）, Wanfang database, and VIP database, without limitation on language, were included with the time limitation from Jan 1982 to Dec 2012 by retrieval of relative original clinical research articles. Results： Nineteen articles where contains 1,840 diabetes patients were obtained, in which no adverse reactions were reported. Of these, 14 literatures involved the effect of fasting blood glucose （FBG）, 10 involved that of postprandial 2-h blood glucose （P2hBG）, and 19 involved the overall efficacy based on the national Chinese medicine （CM） diagnosis and treatment standard of diabetes. All the meta-analysis results prefer to the ＂TTSD＂ groups （CM＋Westem medicine Based on I-I＇SD）. The results show that, beside the efficacy of Westem medicine, the concentrations of FBG and P2hBG in ＂TTSD＂ groups continue to drop with statistical significance. For ＂TTSD＂ groups, the FBG subsequently dropped 1.03 mmol/L, 95%CI [1.24,0.82] （P〈0.00001）, the P2hBG subsequently dropped 1.09 mmol/L, 95% CI [1.61, 0.57] （P〈0.0001）, and the overall efficacies benefit 3.46 times those of Western medicine alone, 95% CI [2.67,4.48] （P〈0.00001）. Conclusions： The CM by the diagnosis and treatment of type 2 diabetes based on ＂TTSD might be safe and effective, and could better improve both blood glucose and the overall status of patients, including symptoms.展开更多
中点钳位(neutral point clamped,NPC)型三电平逆变器并网工作环境恶劣,IGBT面临单管与双管同时故障的挑战,这使得故障特征之间的差异变得非常微弱,进而导致双管故障的识别精度难以有效提升。为此,提出了一种新的故障诊断方法,该方法结...中点钳位(neutral point clamped,NPC)型三电平逆变器并网工作环境恶劣,IGBT面临单管与双管同时故障的挑战,这使得故障特征之间的差异变得非常微弱,进而导致双管故障的识别精度难以有效提升。为此,提出了一种新的故障诊断方法,该方法结合了多通道的二维递归融合图和轻量化多尺度残差(lightweightmultiscale convolutional residuals,LMCR)网络。首先,通过仿真获取三相电流信号作为故障信号;再利用递归图(recurrence plot,RP)将三相电流信号分别转化为二维图并进行多通道融合,以捕捉时间序列中的周期性、突变点和趋势等特征;最后,将递归融合图作为输入,输入到LMCR模型中进行故障识别,LMCR模型整合多级Inception结构和残差网络,用于提取不同尺度的特征并融合这些特征,从而保证网络的梯度消失和爆炸。实验结果显示,该方法在IGBT故障识别中表现出色,无噪声环境下平均识别准确率达100%,噪声环境中也达到了92.53%,充分证明了该方法具有较强的特征提取能力和优异的抗噪性能。展开更多
文摘Objective： To evaluate the efficacy and safety of ＂Three-Typed Syndrome Differentiation＂ （I-TSD） in treating type 2 diabetes mellitus patients. Methods： A systematic review and meta-analysis was done based on the clinical diabetes treatment literature of the ＂I-I＇SD＂. Overseas databases like the PubMed/MEDLINE, EMBASE, Cochrane Library and Cochrane Central Register of Controlled Clinical Trials, and China databases like China Biology Medicine Disc （CBM）, Chinese national Knowledge Infrastructure （CNKI）, Wanfang database, and VIP database, without limitation on language, were included with the time limitation from Jan 1982 to Dec 2012 by retrieval of relative original clinical research articles. Results： Nineteen articles where contains 1,840 diabetes patients were obtained, in which no adverse reactions were reported. Of these, 14 literatures involved the effect of fasting blood glucose （FBG）, 10 involved that of postprandial 2-h blood glucose （P2hBG）, and 19 involved the overall efficacy based on the national Chinese medicine （CM） diagnosis and treatment standard of diabetes. All the meta-analysis results prefer to the ＂TTSD＂ groups （CM＋Westem medicine Based on I-I＇SD）. The results show that, beside the efficacy of Westem medicine, the concentrations of FBG and P2hBG in ＂TTSD＂ groups continue to drop with statistical significance. For ＂TTSD＂ groups, the FBG subsequently dropped 1.03 mmol/L, 95%CI [1.24,0.82] （P〈0.00001）, the P2hBG subsequently dropped 1.09 mmol/L, 95% CI [1.61, 0.57] （P〈0.0001）, and the overall efficacies benefit 3.46 times those of Western medicine alone, 95% CI [2.67,4.48] （P〈0.00001）. Conclusions： The CM by the diagnosis and treatment of type 2 diabetes based on ＂TTSD might be safe and effective, and could better improve both blood glucose and the overall status of patients, including symptoms.
