A three-phase reactor mathematical model was set up to simulate and design a three-phase bubble column reactor for direct synthesis of dimethyl ether （DME） from syngas, considering both the influence of part inert c...A three-phase reactor mathematical model was set up to simulate and design a three-phase bubble column reactor for direct synthesis of dimethyl ether （DME） from syngas, considering both the influence of part inert carrier backmixing on transfer and the influence of catalyst grain sedimentation on reaction. On the basis of this model, the influences of the size and reaction conditions of a 100000 t/a DME reactor on capacity were investigated. The optimized size of the 10000 t/a DME synthesis reactor was proposed as follows： diameter 3.2 m, height 20 m, built-in 400 tube heat exchanger （Ф 38×2 mm）, and inert heat carrier paraffin oil 68 t and catalyst 34.46 t. Reaction temperature and pressure were important factors influencing the reaction conversion for different size reactors. Under the condition of uniform catalyst concentration distribution, higher pressure and temperature were proposed to achieve a higher production capacity of DME. The best ratio of fresh syngas for DME synthesis was 2.04.展开更多
To solve the problem of robust servo performance of Flight Environment Testbed(FET)of Altitude Ground Test Facilities(AGTF) over the whole operational envelope, a two-degree-offreedom μ synthesis method based on Line...To solve the problem of robust servo performance of Flight Environment Testbed(FET)of Altitude Ground Test Facilities(AGTF) over the whole operational envelope, a two-degree-offreedom μ synthesis method based on Linear Parameter Varying(LPV) schematic is proposed, and meanwhile a new structure frame of μ synthesis control on two degrees of freedom with double integral and weighting functions is presented, which constitutes a core support part of the paper. Aimed at the problem of reference command's rapid change, one freedom feed forward is adopted, while another freedom output feedback is used to meet good servo tracking as well as disturbance and noise rejection; furthermore, to overcome the overshoot problem and acquire dynamic tuning,the integral is introduced in inner loop, and another integral controller is used in outer loop in order to guarantee steady errors; additionally, two performance weighting functions are designed to achieve robust specialty and control energy limit considering the uncertainties in system. As the schedule parameters change over large flight envelope, the stability of closed-loop LPV system is proved using Lyapunov inequalities. The simulation results show that the relative tracking errors of temperature and pressure are less than 0.5% with LPV μ synthesis controller. Meanwhile, compared with non-LPV μ synthesis controller in large uncertainty range, the proposed approach in this research can ensure robust servo performance of FET over the whole operational envelope.展开更多
The synthesis and characterization of a series of metal porphyrins, MII(Por), {Por=dianionic of 5, 10, 15, 20-tetrakis [4-(4′-bromobutyloxy) phenyl]porphyrinato and 5, 10, 15, 20-tetrakis [4-(4′-butyloxypyridine bro...The synthesis and characterization of a series of metal porphyrins, MII(Por), {Por=dianionic of 5, 10, 15, 20-tetrakis [4-(4′-bromobutyloxy) phenyl]porphyrinato and 5, 10, 15, 20-tetrakis [4-(4′-butyloxypyridine bromide)phenyl]porphyrinato, M=Zn, Cu, Mn, Co, Ni, Ru-CO} were described. The complexes 3a-3e were prepared from the reactions of compound 2 with metal acetates in chloroform, and the treatment of 3a-3f with excess of pyridine gave corresponding complexes 4a-4f. These new compounds were identified by absorption spectroscopies,1H-NMR and elemental analyses. The results of biological activity testing for 4a-4f revealed that 4a and 4c had stronger inhibiting action on the growth metabolism ofEsche richia coli.展开更多
Thirteen thiomorpholine-bearing compounds were designed and synthesized as dipeptidyl peptidase IV（DPP-IV） inhibitors, with natural and non-natural L-amino acids as the starting materials.Their structures were chara...Thirteen thiomorpholine-bearing compounds were designed and synthesized as dipeptidyl peptidase IV（DPP-IV） inhibitors, with natural and non-natural L-amino acids as the starting materials.Their structures were characterized by ~1H NMR,^（13）C NMR and HR-MS.The target compounds were screened for the DPP-IV inhibition,and the preliminary SAR result was obtained.Particularly, compounds 4c,4d and 4f with good DPP-IV inhibition in vitro were further evaluated through a mouse oral glucose tolerance test （OGTT）.The preliminary result showed the potential value for further studies on those thiomorpholine-bearing compounds as DPP-IV inhibitors.展开更多
The synthesis of selenamorpholine hydrate was described and its antimutagenic effects were investigated by the Ames tests. The results indicated that the mutation induced by the indirect mutagen 2-AF was inhibited ob...The synthesis of selenamorpholine hydrate was described and its antimutagenic effects were investigated by the Ames tests. The results indicated that the mutation induced by the indirect mutagen 2-AF was inhibited obviously by selenamorpholine hydrate at the dosage of Se 0. 16--100 ug /dish for 35. 8% -53. 7% (TA_97) and the mutation induced by direct mutagen Dexon was inhibited for 6. 2% --30. 0% (TA_97,) and 2. 3% ~34. 1% (TA_100). The mutagenesis of the indirect mutagen cyclophosphamide was suppressed for 5.4%~ 16. 1% by selenamorpholine hydrate at the dosage of Se 0. 16--100 ug /dish.展开更多
The synthesis, characterization, and biological activities of a series of metal porphyrins were described. The complexes 3a similar to 3e were prepared from the reaction of compound 2 with M(OAc)(2) in CHCl3, and the ...The synthesis, characterization, and biological activities of a series of metal porphyrins were described. The complexes 3a similar to 3e were prepared from the reaction of compound 2 with M(OAc)(2) in CHCl3, and the treatment of 3a similar to 3f with pyridine gave corresponding complexes 4a similar to 4f. These new compounds were identified by absorption spectroscopies, H-1 NMR and elemental analysis. The results of biological activity,testing revealed that 4a and 4c had stronger inhibiting action for Escherichia coli (CCTCC AB91115).展开更多
One of the main shortcomings of standard sampling synthesis is the very limited number of sound parameters that are user-controllable. In the most general case, the user can choose a particular pitch, duration, and am...One of the main shortcomings of standard sampling synthesis is the very limited number of sound parameters that are user-controllable. In the most general case, the user can choose a particular pitch, duration, and amplitude. If the sampler allows control over articulation, it simply switches from one sound sample to another. This makes fine-tuning of musical performances demanding and time-consuming if not an impossibility altogether. A synthesis system has been developed at the Academy of Music in Krakow, Poland. It uses a large collection of samples that contain short sequences of notes. The system implements a number of techniques to seamlessly connect recorded sequences, to control note durations as well as the tempo and the dynamics envelopes. Samples are automatically chosen, modified, and connected to keep the recorded, natural note transitions intact. The system uses performance rules to introduce variations into the regular playback akin to live performances by musicians. A user can either control the parameters manually or choose a desired expression and leave the particular decisions to the system. However, it is necessary to examine which parameters have the greatest impact on the listeners’ impression and determine useful values. 15 expert listeners compared and evaluated variants of musical performances produced by the synthesis system with different sets of parameters. The paper discusses a selection of the examined parameters, the test methods employed and the results obtained.展开更多
This work aims at solving the problems of difficult dispersion,easy oxidation and high cost of nano carbon during application,carbon/magnesium aluminate spinel(C/MgAl_(2)O_(4))composite powders were prepared using MgC...This work aims at solving the problems of difficult dispersion,easy oxidation and high cost of nano carbon during application,carbon/magnesium aluminate spinel(C/MgAl_(2)O_(4))composite powders were prepared using MgC2O4·2H2O,MgO2,Al2O3 powder,and Al powder as raw materials by combustion synthesis.The results indicate that with the maximum MgC2O4·2H2O addition of 33.34 mass%,the prepared powder contains 1.17 mass%of carbon and carbon distributes among spinel grains.The MgAl_(2)O_(4)spinel shows both granular and rod-like morphologies.The granular MgAl_(2)O_(4)spinel is generated from mutual diffusion between MgO and Al2O3;while the rod-like MgAl_(2)O_(4)spinel is mainly formed by the vapor-solid growth mechanism from Mg vapor and Al2O3.展开更多
The flutter characteristics of folding control fins with freeplay are investigated by numer- ical simulation and flutter wind tunnel tests. Based on the characteristics of the structures, fins with different freeplay ...The flutter characteristics of folding control fins with freeplay are investigated by numer- ical simulation and flutter wind tunnel tests. Based on the characteristics of the structures, fins with different freeplay angles are designed. For a 0° angle of attack, wind tunnel tests of these fins are conducted, and vibration is observed by accelerometers and a high-speed camera. By the expansion of the connected relationships, the governing equations of fit for the nonlinear aeroelastic analysis are established by the free-interface component mode synthesis method. Based on the results of the wind tunnel tests, the flutter characteristics of fins with different freeplay angles are analyzed. The results show that the vibration divergent speed is increased, and the divergent speed is higher than the flutter speed of the nominal linear system. The vibration divergent speed is increased along with an increase in the freeplay angle. The developed free-interface component mode synthesis method could be used to establish governing equations and to analyze the characteristics of nonlinear aeroe- lastic systems. The results of the numerical simulations and the wind tunnel tests indicate the same trends and critical velocities.展开更多
Five catalytic processes and their catalysts will be introduced in my talk.Firstly,the demonstration test(3000 ton/a)results using a novel catalyst Co/SiO2 with egg-shell structure and the strategies for this catalyst...Five catalytic processes and their catalysts will be introduced in my talk.Firstly,the demonstration test(3000 ton/a)results using a novel catalyst Co/SiO2 with egg-shell structure and the strategies for this catalyst preparation based on the issues from the mass transfer of produced wax from F-T synthesis will be discussed.Recent progresses on C2-oxygenate synthesis from syngas over a Rh/SiO2 catalyst and a 10 thousands ton/a demonstration test facility in China will be built in 2010 will be reported in the second section.A naphtha and diesel distillate which cut off the heavier end of S-F-A distribution direct synthesis with low methane selectivity from syngas over a Co/AC1 catalyst and a 10000 ton/a demonstration test with a bubble column slurry reactor will be talked about in this speech.A highα-alcohols of C2-C18 direct synthesis with more than 50 wt%selectivity and low methane and methanol selectivities from syngas over a Co2C/AC2 catalyst,a 3000 ton/a demonstration test with a bubble column slurry reactor and the primary fundamental understandings will be detailedly discussed in the forth section.In situ formation of homogeneous active sites on the surface of supported Rh heterogeneous catalysts and their application in hydroformylation of olefins will be introduced in fifth section.展开更多
With the development of VLSI technology, testing design method has been one indispensable fact of the research of VLSI design methodology. Technology of testing design can observably reduce the cost of the chip and he...With the development of VLSI technology, testing design method has been one indispensable fact of the research of VLSI design methodology. Technology of testing design can observably reduce the cost of the chip and help win in time- to-market. Conventional methods of design for test improve the testing performance of the system by modifing the gate-level architecture generally. Re-search in high-level test synthesis has been emphasized on fitting for the trend of high-level VLSI design. In this paper, based on the analysis of different types of testing design methods, a novel compound strategy of design for test in VLSI system is proposed.展开更多
基金This work was supported by the National Basic Research Program of China (2005CB221205)
文摘A three-phase reactor mathematical model was set up to simulate and design a three-phase bubble column reactor for direct synthesis of dimethyl ether （DME） from syngas, considering both the influence of part inert carrier backmixing on transfer and the influence of catalyst grain sedimentation on reaction. On the basis of this model, the influences of the size and reaction conditions of a 100000 t/a DME reactor on capacity were investigated. The optimized size of the 10000 t/a DME synthesis reactor was proposed as follows： diameter 3.2 m, height 20 m, built-in 400 tube heat exchanger （Ф 38×2 mm）, and inert heat carrier paraffin oil 68 t and catalyst 34.46 t. Reaction temperature and pressure were important factors influencing the reaction conversion for different size reactors. Under the condition of uniform catalyst concentration distribution, higher pressure and temperature were proposed to achieve a higher production capacity of DME. The best ratio of fresh syngas for DME synthesis was 2.04.
文摘To solve the problem of robust servo performance of Flight Environment Testbed(FET)of Altitude Ground Test Facilities(AGTF) over the whole operational envelope, a two-degree-offreedom μ synthesis method based on Linear Parameter Varying(LPV) schematic is proposed, and meanwhile a new structure frame of μ synthesis control on two degrees of freedom with double integral and weighting functions is presented, which constitutes a core support part of the paper. Aimed at the problem of reference command's rapid change, one freedom feed forward is adopted, while another freedom output feedback is used to meet good servo tracking as well as disturbance and noise rejection; furthermore, to overcome the overshoot problem and acquire dynamic tuning,the integral is introduced in inner loop, and another integral controller is used in outer loop in order to guarantee steady errors; additionally, two performance weighting functions are designed to achieve robust specialty and control energy limit considering the uncertainties in system. As the schedule parameters change over large flight envelope, the stability of closed-loop LPV system is proved using Lyapunov inequalities. The simulation results show that the relative tracking errors of temperature and pressure are less than 0.5% with LPV μ synthesis controller. Meanwhile, compared with non-LPV μ synthesis controller in large uncertainty range, the proposed approach in this research can ensure robust servo performance of FET over the whole operational envelope.
基金Supported by the National Natural Science Foundation of China( No:2 9972 0 35 ) and the Zi-Qiang Science Foundationof Wuhan University2 0 0 0
文摘The synthesis and characterization of a series of metal porphyrins, MII(Por), {Por=dianionic of 5, 10, 15, 20-tetrakis [4-(4′-bromobutyloxy) phenyl]porphyrinato and 5, 10, 15, 20-tetrakis [4-(4′-butyloxypyridine bromide)phenyl]porphyrinato, M=Zn, Cu, Mn, Co, Ni, Ru-CO} were described. The complexes 3a-3e were prepared from the reactions of compound 2 with metal acetates in chloroform, and the treatment of 3a-3f with excess of pyridine gave corresponding complexes 4a-4f. These new compounds were identified by absorption spectroscopies,1H-NMR and elemental analyses. The results of biological activity testing for 4a-4f revealed that 4a and 4c had stronger inhibiting action on the growth metabolism ofEsche richia coli.
基金the Fundamental Scientific Research Fund ofInstitute of Materia Medica(Li Peng 504-Basic 10 DPP IV inhibitor)for financial support on this project
文摘Thirteen thiomorpholine-bearing compounds were designed and synthesized as dipeptidyl peptidase IV（DPP-IV） inhibitors, with natural and non-natural L-amino acids as the starting materials.Their structures were characterized by ~1H NMR,^（13）C NMR and HR-MS.The target compounds were screened for the DPP-IV inhibition,and the preliminary SAR result was obtained.Particularly, compounds 4c,4d and 4f with good DPP-IV inhibition in vitro were further evaluated through a mouse oral glucose tolerance test （OGTT）.The preliminary result showed the potential value for further studies on those thiomorpholine-bearing compounds as DPP-IV inhibitors.
文摘The synthesis of selenamorpholine hydrate was described and its antimutagenic effects were investigated by the Ames tests. The results indicated that the mutation induced by the indirect mutagen 2-AF was inhibited obviously by selenamorpholine hydrate at the dosage of Se 0. 16--100 ug /dish for 35. 8% -53. 7% (TA_97) and the mutation induced by direct mutagen Dexon was inhibited for 6. 2% --30. 0% (TA_97,) and 2. 3% ~34. 1% (TA_100). The mutagenesis of the indirect mutagen cyclophosphamide was suppressed for 5.4%~ 16. 1% by selenamorpholine hydrate at the dosage of Se 0. 16--100 ug /dish.
基金the National Natural Science Foundation of China is gratefully acknowledged (No. 29972035).
文摘The synthesis, characterization, and biological activities of a series of metal porphyrins were described. The complexes 3a similar to 3e were prepared from the reaction of compound 2 with M(OAc)(2) in CHCl3, and the treatment of 3a similar to 3f with pyridine gave corresponding complexes 4a similar to 4f. These new compounds were identified by absorption spectroscopies, H-1 NMR and elemental analysis. The results of biological activity,testing revealed that 4a and 4c had stronger inhibiting action for Escherichia coli (CCTCC AB91115).
文摘One of the main shortcomings of standard sampling synthesis is the very limited number of sound parameters that are user-controllable. In the most general case, the user can choose a particular pitch, duration, and amplitude. If the sampler allows control over articulation, it simply switches from one sound sample to another. This makes fine-tuning of musical performances demanding and time-consuming if not an impossibility altogether. A synthesis system has been developed at the Academy of Music in Krakow, Poland. It uses a large collection of samples that contain short sequences of notes. The system implements a number of techniques to seamlessly connect recorded sequences, to control note durations as well as the tempo and the dynamics envelopes. Samples are automatically chosen, modified, and connected to keep the recorded, natural note transitions intact. The system uses performance rules to introduce variations into the regular playback akin to live performances by musicians. A user can either control the parameters manually or choose a desired expression and leave the particular decisions to the system. However, it is necessary to examine which parameters have the greatest impact on the listeners’ impression and determine useful values. 15 expert listeners compared and evaluated variants of musical performances produced by the synthesis system with different sets of parameters. The paper discusses a selection of the examined parameters, the test methods employed and the results obtained.
文摘This work aims at solving the problems of difficult dispersion,easy oxidation and high cost of nano carbon during application,carbon/magnesium aluminate spinel(C/MgAl_(2)O_(4))composite powders were prepared using MgC2O4·2H2O,MgO2,Al2O3 powder,and Al powder as raw materials by combustion synthesis.The results indicate that with the maximum MgC2O4·2H2O addition of 33.34 mass%,the prepared powder contains 1.17 mass%of carbon and carbon distributes among spinel grains.The MgAl_(2)O_(4)spinel shows both granular and rod-like morphologies.The granular MgAl_(2)O_(4)spinel is generated from mutual diffusion between MgO and Al2O3;while the rod-like MgAl_(2)O_(4)spinel is mainly formed by the vapor-solid growth mechanism from Mg vapor and Al2O3.
文摘The flutter characteristics of folding control fins with freeplay are investigated by numer- ical simulation and flutter wind tunnel tests. Based on the characteristics of the structures, fins with different freeplay angles are designed. For a 0° angle of attack, wind tunnel tests of these fins are conducted, and vibration is observed by accelerometers and a high-speed camera. By the expansion of the connected relationships, the governing equations of fit for the nonlinear aeroelastic analysis are established by the free-interface component mode synthesis method. Based on the results of the wind tunnel tests, the flutter characteristics of fins with different freeplay angles are analyzed. The results show that the vibration divergent speed is increased, and the divergent speed is higher than the flutter speed of the nominal linear system. The vibration divergent speed is increased along with an increase in the freeplay angle. The developed free-interface component mode synthesis method could be used to establish governing equations and to analyze the characteristics of nonlinear aeroe- lastic systems. The results of the numerical simulations and the wind tunnel tests indicate the same trends and critical velocities.
文摘Five catalytic processes and their catalysts will be introduced in my talk.Firstly,the demonstration test(3000 ton/a)results using a novel catalyst Co/SiO2 with egg-shell structure and the strategies for this catalyst preparation based on the issues from the mass transfer of produced wax from F-T synthesis will be discussed.Recent progresses on C2-oxygenate synthesis from syngas over a Rh/SiO2 catalyst and a 10 thousands ton/a demonstration test facility in China will be built in 2010 will be reported in the second section.A naphtha and diesel distillate which cut off the heavier end of S-F-A distribution direct synthesis with low methane selectivity from syngas over a Co/AC1 catalyst and a 10000 ton/a demonstration test with a bubble column slurry reactor will be talked about in this speech.A highα-alcohols of C2-C18 direct synthesis with more than 50 wt%selectivity and low methane and methanol selectivities from syngas over a Co2C/AC2 catalyst,a 3000 ton/a demonstration test with a bubble column slurry reactor and the primary fundamental understandings will be detailedly discussed in the forth section.In situ formation of homogeneous active sites on the surface of supported Rh heterogeneous catalysts and their application in hydroformylation of olefins will be introduced in fifth section.
文摘With the development of VLSI technology, testing design method has been one indispensable fact of the research of VLSI design methodology. Technology of testing design can observably reduce the cost of the chip and help win in time- to-market. Conventional methods of design for test improve the testing performance of the system by modifing the gate-level architecture generally. Re-search in high-level test synthesis has been emphasized on fitting for the trend of high-level VLSI design. In this paper, based on the analysis of different types of testing design methods, a novel compound strategy of design for test in VLSI system is proposed.
