AIM:To build a functional generalized estimating equation(GEE)model to detect glaucomatous visual field progression and compare the performance of the proposed method with that of commonly employed algorithms.METHODS:...AIM:To build a functional generalized estimating equation(GEE)model to detect glaucomatous visual field progression and compare the performance of the proposed method with that of commonly employed algorithms.METHODS:Totally 716 eyes of 716 patients with primary open angle glaucoma(POAG)with at least 5 reliable 24-2 test results and 2y of follow-up were selected.The functional GEE model was used to detect perimetric progression in the training dataset(501 eyes).In the testing dataset(215 eyes),progression was evaluated the functional GEE model,mean deviation(MD)and visual field index(VFI)rates of change,Advanced Glaucoma Intervention Study(AGIS)and Collaborative Initial Glaucoma Treatment Study(CIGTS)scores,and pointwise linear regression(PLR).RESULTS:The proposed method showed the highest proportion of eyes detected as progression(54.4%),followed by the VFI rate(34.4%),PLR(23.3%),and MD rate(21.4%).The CIGTS and AGIS scores had a lower proportion of eyes detected as progression(7.9%and 5.1%,respectively).The time to detection of progression was significantly shorter for the proposed method than that of other algorithms(adjusted P≤0.019).The VFI rate displayed moderate pairwise agreement with the proposed method(k=0.47).CONCLUSION:The functional GEE model shows the highest proportion of eyes detected as perimetric progression and the shortest time to detect perimetric progression in patients with POAG.展开更多
High-altitude cold regions exhibit complex geological and environmental conditions,fostering steep rock slopes with macroscopic joints and mesoscopic freeze-thaw(F-T)damage.Cyclic loading further exacerbates rock inst...High-altitude cold regions exhibit complex geological and environmental conditions,fostering steep rock slopes with macroscopic joints and mesoscopic freeze-thaw(F-T)damage.Cyclic loading further exacerbates rock instability,yet the fracture mechanisms and load response relationships remain poorly understood.This study prepared intact and fractured sandstone specimens,subjected them to F-T cycles and graded loading-unloading,and monitored their structural evolution via X-ray computed tomography.First,the progressive failure process was investigated from both qualitative morphologic features and quantitative void parameters.The results showed that intact and fractured sandstone instability behaviors are determined by F-T damage and joint arrangement,respectively.However,both indicate that precursory localization of failure can only be detected when heterogeneous damage exists in advance.Furthermore,the void parameters of undamaged intact sandstone exhibit power-law acceleration,while damaged sandstones are characterized by a trend of initial decrease followed by an increase.Subsequently,a damage constitutive model for freeze-thawed fractured sandstone under graded loading-unloading was established.This model is based on the Lemaitre strain equivalence hypothesis and defines the coupled damage variable through multivariable indicators.In this framework,the material damage induced by fractures and F-T is unified and characterized by void parameters;while the load-induced damage is integrated with the energy linear allocation law and defined by damage energy.Thus,the stress-strain theoretical relationship is depicted,and the model is validated as reliable.Finally,a conceptual model of rock damage due to F-T and loading-unloading was proposed by combining the microscopic testing results from X-ray diffraction and scanning electron microscopy.展开更多
Generally, most soil slope failures are induced by rainfall infiltration, a process that involves interactions between the liquid phase, gas phase,and solid skeleton in an unsaturated soil slope. In this study, a loos...Generally, most soil slope failures are induced by rainfall infiltration, a process that involves interactions between the liquid phase, gas phase,and solid skeleton in an unsaturated soil slope. In this study, a loosely coupled liquid-gas-solid three-phase model, linking two numerical codes,TOUGH2/EOS3, which is used for water-air two-phase flow analysis, and FLAC^(3D), which is used for mechanical analysis, was established. The model was validated through a documented water drainage experiment over a sandy column and a comparison of the results with measured data and simulated results from other researchers. The proposed model was used to investigate the features of water-air two-phase flow and stress fields in an unsaturated soil slope during rainfall infiltration. The slope stability analysis was then performed based on the simulated water-air two-phase seepage and stress fields on a given slip surface. The results show that the safety factor for the given slip surface decreases first, then increases, and later decreases until the rainfall stops. Subsequently, a sudden rise occurs. After that, the safety factor decreases continually and reaches its lowest value, and then increases slowly to a steady value. The lowest value does not occur when the rainfall stops, indicating a delayed effect of the safety factor. The variations of the safety factor for the given slip surface are therefore caused by a combination of pore-air pressure, matric suction, normal stress, and net normal stress.展开更多
A three-phase confocal elliptical cylinder model is proposed to analyze micromechanics of one-dimensional hexagonal piezoelectric quasicrystal （PQC） compos- ites. Exact solutions of the phonon, phason, and electric ...A three-phase confocal elliptical cylinder model is proposed to analyze micromechanics of one-dimensional hexagonal piezoelectric quasicrystal （PQC） compos- ites. Exact solutions of the phonon, phason, and electric fields are obtained by using the conformal mapping combined with the Laurent expansion technique when the model is subject to far-field anti-plane mechanical and in-plane electric loadings. The effective elec- troelastic constants of several different composites made up of PQC, quasicrystal （QC）, and piezoelectric （PE） materials are predicted by the generalized self-consistent method. Numerical examples are conducted to show the effects of the volume fraction and the cross-sectional shape of inclusion （or fiber） on the effective electroelastic constants of these composites. Compared with other micromechanical methods, the generalized self- consistent and Mori-Tanaka methods can predict the effective electroelastic constants of the composites consistently.展开更多
Bone remodelling keeps going through the lifespan of human by bone formation and bone resorption.In the craniofacial region,mandibles act as the main force for biting and chewing,and also become susceptible to a commo...Bone remodelling keeps going through the lifespan of human by bone formation and bone resorption.In the craniofacial region,mandibles act as the main force for biting and chewing,and also become susceptible to a common bone-loss disease,namely,apical periodontitis,once infected dental pulp is not treated timely,during which bone resorption occurs from the apical foramen to the apical bone area.Although conventional root canal treatment(RCT)can remove the most of the infection,chronical apical periodontitis due to incomplete removal of dental pulp and subsequent microleakage will become refractory and more challenging,and this process has scarcely been specifically studied as a bone remodelling issue in rat models.Therefore,to study chronical and refractory apical periodontitis owing to incomplete cleaning of infected dental pulp and microleackage in vivo,we establish a modified rat model of gradually progressive apical periodontitis by sealing residual necrotic dental pulp and introducing limited saliva,which simulates gradually progressive apical periodontitis,as observed in the clinical treatment of chronical and refractory apical periodontitis.We show that bone-loss is inevitable and progressive in this case of apical periodontitis,which confirms again that complete and sound root canal treatment is crucial to halt the progression of chronical and refractory apical periodontitis and promote bone formation.Interestingly,bone remodelling was enhanced at the initial stage of apical periodontitis in this model while reduced with a high osteoblast number afterwards,as shown by the time course study of the modified model.Suggesting that the pathological apical microenvironment reserve its hard tissue formation ability to some degree but in a disturbed manner.Hopefully,our findings can provide insights for future bone regenerative treatment for apical periodontitisassociated bone loss.展开更多
By means of the computational fluid dynamics software Fluent 6.3, a mathematical model of three-dimensional three-phase fluid flow field in the molten bath of electric arc furnace （EAF） with side accessorial oxygen ...By means of the computational fluid dynamics software Fluent 6.3, a mathematical model of three-dimensional three-phase fluid flow field in the molten bath of electric arc furnace （EAF） with side accessorial oxygen lances was developed to study the transient phenomena of oxygen jet impingement on the molten steel and the molten slag. The water modeling experiment was carried out to verify the simulation results. The impingement of the supersonic oxygen jet caused impact dent on the molten steel surface accordingly. The area of impact dent changed almost in linear relationship to flow rate of oxygen jet, which can be expressed by a deduced mathematical equation. And the relationship between the impact force of oxygen iet and the correspondingly formed apparent static pressure on molten bath was obtained, which was in linear relationship and a direct proportion, and can also be expressed by a deduced mathematical equation.展开更多
A progressive micromechanical method is presented in order to predict the elastic constants of polydispersed composites including multi-directional or randomly ori- ented reinforcement particles. Heterogeneities of va...A progressive micromechanical method is presented in order to predict the elastic constants of polydispersed composites including multi-directional or randomly ori- ented reinforcement particles. Heterogeneities of various types are introduced into the matrices in a gradual manner. At each step, the Mori-Tanaka method is used to ob- tain the stiffness tensor of the intermediate medium used as a matrix of the following step. The proposed method is capable of introducing any kind of heterogeneities based on their dimensions, orientations, mechanical properties, and volume fractions to the ma- trix. Furthermore, suitable probability density functions can be defined for physical and structural parameters of the composite, including the level of the filler-matrix interfacial bonding, the aspect ratio, and the orientation of reinforcement particles. The efficiency of the iterative approach and the convergence of the solution are studied by computing the stiffness tensors of unidirectional and bidirectional particulate composites. The results of the present study are also compared with the literature data for a randomly oriented particulate composite.展开更多
The cooling channel process is a rehocasting method by which the prematerial with globular microstructure can be produced to fit the thixocasting process.A three-phase model based on volume averaging approach is propo...The cooling channel process is a rehocasting method by which the prematerial with globular microstructure can be produced to fit the thixocasting process.A three-phase model based on volume averaging approach is proposed to simulate the cooling channel process of A356 Aluminum alloy.The three phases are liquid,solid and air respectively and treated as separated and interacting continua,sharing a single pressure field.The mass,momentum,enthalpy transport equations for each phase are solved.The developed model can predict the evolution of liquid,solid and air fraction as well as the distribution of grain density and grain size.The effect of pouring temperature on the grain density,grain size and solid fraction is analyzed in detail.展开更多
Ultra-wideband （UWB） microwave imaging is a promising method for breast cancer detection based on the large contrast of electric parameters between the malignant tumor and its surrounded normal breast organisms. In ...Ultra-wideband （UWB） microwave imaging is a promising method for breast cancer detection based on the large contrast of electric parameters between the malignant tumor and its surrounded normal breast organisms. In the case of multiple tumors being present, the conventional imaging approaches may be ineffective to detect all the tumors clearly. In this paper, a progressive processing method is proposed for detecting more than one tumor. The method is divided into three stages： primary detection, refocusing and image optimization. To test the feasibility of the approach, a numerical breast model is developed based on the realistic magnetic resonance image （MRI）. Two tumors are assumed embedded in different positions. Successful detection of a 3.6 mm-diameter tumor at a depth of 42 mm is achieved. The correct information of both tumors is shown in the reconstructed image, suggesting that the progressive processing method is promising for multi-tumor detection.展开更多
The present study aims at investigating the effect of temperature variation due to heat transfer between the formation and drilling fluids considering influx from the reservoir in the underbalanced drilling condition....The present study aims at investigating the effect of temperature variation due to heat transfer between the formation and drilling fluids considering influx from the reservoir in the underbalanced drilling condition. Gas-liquid-solid three-phase flow model considering transient thermal interaction with the formation was applied to simulate wellbore fluid to calculate the wellbore temperature and pressure and analyze the influence of different parameters on fluid pressure and temperature distribution in annulus. The results show that the non-isothermal three-phase flow model with thermal consideration gives more accurate prediction of bottom-hole pressure(BHP) compared to other models considering geothermal temperature. Viscous dissipation, the heat produced by friction between the rotating drilling-string and well wall and drill bit drilling, and influx of oil and gas from reservoir have significant impact on the distribution of fluid temperature in the wellbore, which in turn affects the BHP. Bottom-hole fluid temperature decreases with increasing liquid flow rate, circulation time, and specific heat of liquid and gas but it increases with increasing in gas flow rate. It was found that BHP is strongly depended on the gas and liquid flow rates but it has weak dependence on the circulation time and specific heat of liquid and gas. BHP increase with increasing liquid flow rate and decreases with increasing gas flow rate.展开更多
Finite-control-set model predictive control(FCSMPC)has advantages of multi-objective optimization and easy implementation.To reduce the computational burden and switching frequency,this article proposed a simplified M...Finite-control-set model predictive control(FCSMPC)has advantages of multi-objective optimization and easy implementation.To reduce the computational burden and switching frequency,this article proposed a simplified MPC for dual three-phase permanent magnet synchronous motor(DTPPMSM).The novelty of this method is the decomposition of prediction function and the switching optimization algorithm.Based on the decomposition of prediction function,the current increment vector is obtained,which is employed to select the optimal voltage vector and calculate the duty cycle.Then,the computation burden can be reduced and the current tracking performance can be maintained.Additionally,the switching optimization algorithm was proposed to optimize the voltage vector action sequence,which results in lower switching frequency.Hence,this control strategy can not only reduce the computation burden and switching frequency,but also maintain the steady-state and dynamic performance.The simulation and experimental results are presented to verify the feasibility of the proposed strategy.展开更多
The paper presents an accurate analytical subdomain model for predicting the electromagnetic performance in the symmetrical dual three-phase surface-mounted permanent magnet synchronous machine(PMSM)under open-phase f...The paper presents an accurate analytical subdomain model for predicting the electromagnetic performance in the symmetrical dual three-phase surface-mounted permanent magnet synchronous machine(PMSM)under open-phase faulty conditions.The model derivations are extended from previous accurate subdomain models accounting for slotting effects.Compared with most conventional subdomain models for traditional three-phase machines with nonoverlapping winding arrangement,the subdomain model proposed in this paper applied for the 24-slot/4-pole dual three-phase machine with symmetrical overlapping winding arrangement.In order to investigate the postfault electromagnetic performance,the reconfigured phase currents and then current density distribution in stator slots under different open-circuit conditions are discussed.According to the developed model and postfault current density distribution,the steady-state electromagnetic performance,such as the electromagnetic torque and unbalanced magnetic force,under open-circuit faulty conditions are obtained.For validation purposes,finite element analysis(FEA)is employed to validate the analytical results.The result indicate that the postfault electromagnet performance can be accurately predicted by the proposed subdomain model,which is in good agreement with FEA results.展开更多
patients with PPF.TCM treatments are typically diverse and individualized,requiring urgent development of efficient and precise design strategies to identify effective treatment options.We designed an innovative Bayes...patients with PPF.TCM treatments are typically diverse and individualized,requiring urgent development of efficient and precise design strategies to identify effective treatment options.We designed an innovative Bayesian adaptive two-stage trial,hoping to provide new ideas for the rapid evaluation of the effectiveness of TCM in PPF.An open-label,two-stage,adaptive Bayesian randomized controlled trial will be conducted in China.Based on Bayesian methods,the trial will employ response-adaptive randomization to allocate patients to study groups based on data collected over the course of the trial.The adaptive Bayesian trial design will employ a Bayesian hierarchical model with“stopping”and“continuation”criteria once a predetermined posterior probability of superiority or futility and a decision threshold are reached.The trial can be implemented more efficiently by sharing the master protocol and organizational management mechanisms of the sub-trial we have implemented.The primary patient-reported outcome is a change in the Leicester Cough Questionnaire score,reflecting an improvement in cough-specific quality of life.The adaptive Bayesian trial design may be a promising method to facilitate the rapid clinical evaluation of TCM effectiveness for PPF,and will provide an example for how to evaluate TCM effectiveness in rare and refractory diseases.However,due to the complexity of the trial implementation,sufficient simulation analysis by professional statistical analysts is required to construct a Bayesian response-adaptive randomization procedure for timely response.Moreover,detailed standard operating procedures need to be developed to ensure the feasibility of the trial implementation.展开更多
Landslides triggered by high gas pressure represent a distinct geotechnical hazard,especially in scenarios without significant rainfall.Recent studies have revealed that high-pressure gas accumulation within slopes ca...Landslides triggered by high gas pressure represent a distinct geotechnical hazard,especially in scenarios without significant rainfall.Recent studies have revealed that high-pressure gas accumulation within slopes can be a dominant trigger for large-scale failures although the processes behind this remain not well understood.This study examines how unsaturated soil slopes fail under high gas pressure using a combination of laboratory experiments and numerical simulations.A key discovery is that gas pressure changes slope stability by redistributing pore fluids and altering effective stress,with distinct depthdependent effects.Moreover,a novel concept of critical stable gas pressure(P_(ac))is proposed as a practical threshold for stability assessment,which is depthdependent,with extreme values at shallow and intermediate depths,reflecting the interplay between gas diffusion and overburden resistance.This study advances the mechanistic understanding of gasinduced slope instability and offers actionable benchmarks for managing related risks in engineering projects including waste landfill management and shale gas operations.展开更多
The failure wave has been observed propagating in glass under impact loading since 1991. It is a continuous fracture zone which may be associated with the damage accumulation process during the propagation of shock wa...The failure wave has been observed propagating in glass under impact loading since 1991. It is a continuous fracture zone which may be associated with the damage accumulation process during the propagation of shock waves. A progressive fracture model was proposed to describe the failure wave formation and propagation in shocked glass considering its heterogeneous meso-structures. The original and. nucleated microcracks will expand along the pores and other defects with concomitant dilation when shock loading is below the Hugoniot Elastic Limit. The governing equation of the failure wave is characterized by inelastic bulk strain with material damage and fracture. And the inelastic bulk strain consists of dilatant strain from nucleation and expansion of microcracks and condensed strain from the collapse of the original pores. Numerical simulation of the free surface velocity was performed and found in good agreement with planar impact experiments on K9 glass at China Academy of Engineering Physics. And the longitudinal, lateral and shear stress histories upon the arrival of the failure wave were predicted, which present the diminished shear strength and lost spall strength in the failed layer.展开更多
Polycrystalline ceramics have heterogeneous meso-structures which result in high singularity in stress distribution. Based on this, a progressive fragment model was proposed which describes the failure wave formation ...Polycrystalline ceramics have heterogeneous meso-structures which result in high singularity in stress distribution. Based on this, a progressive fragment model was proposed which describes the failure wave formation and propagation in shocked ceramics. The governing equation of the failure wave was characterized by inelastic bulk strain with material damage and fracture. And the inelastic bulk strain consists of dilatant strain from nucleation and expansion of microcracks and condensed strain from collapse of original pores. Numerical simulation of the free surface velocity was performed in good agreement with planar impact experiments on 92.93% aluminas at China Academy of Engineering Physics. And the longitudinal, lateral and shear stress histories upon the arrival of the failure wave were predicted, which present the diminished shear strength and lost spall strength in the failed layer.展开更多
The dual three-phase PMSM(DTP-PMSM)drives have received wide attention at high-power high-efficiency applications due to their merits of high output current ability and copper-loss-free field excitation.Meanwhile,the ...The dual three-phase PMSM(DTP-PMSM)drives have received wide attention at high-power high-efficiency applications due to their merits of high output current ability and copper-loss-free field excitation.Meanwhile,the DTPPMSM drive provides higher fault-tolerant capability for highreliability applications,e.g.,pumps and actuators in aircraft.For high-power drives with limited switching frequencies and highspeed drives with large fundamental frequencies,the ratio of switching frequency to fundamental frequency,i.e.,the carrier ratio,is usually below 15,which would significantly degrade the control performance.The purpose of this paper is to review the recent work on the modulation and control schemes for improving the operation performance of DTP-PMSM drives with low carrier ratios.Specifically,three categories of methods,i.e.,the space vector modulation based control,the model predictive control(MPC),and the optimized pulse pattern(OPP)based control are reviewed with principles and performance.In addition,brief discussions regarding the comparison and future trends are presented for low-carrier-ratio(LCR)modulation and control schemes of DTP-PMSM drives.展开更多
An in-depth investigation is made on the problem of an arc-shapedinterface insulating crack in a three-phase concentric circularcylindrical piezoelectric composite constitutive model. An exactsolution in series form i...An in-depth investigation is made on the problem of an arc-shapedinterface insulating crack in a three-phase concentric circularcylindrical piezoelectric composite constitutive model. An exactsolution in series form is derived by employing the complex variablemethod. In addition, the distribution of physical quantities such asstresses, strains, electric displacements and electric fields in thewhole field and along the interface is also presented.展开更多
The axial concentration distribution of both particles with betterwetting (forming non-attached system) and poorer wetting (formingattached system) was investigated in a vertical gas-liquid-solidfluidized bed of 4.2 c...The axial concentration distribution of both particles with betterwetting (forming non-attached system) and poorer wetting (formingattached system) was investigated in a vertical gas-liquid-solidfluidized bed of 4.2 cm in diameters and 130 cm in height with thesolids holdup less than 0.05. The one-dimensionalsedimentation-dispersion model could be used satisfactorily todescribe the axial distribution of solids holdup by modifying only amodel parameter, i.e. by means of the terminal settling velocityminus a certain value, which is a functions of gas velocity andconsiders the effect of an additional drag force resulted fromattached rising bubbles.展开更多
基金Supported by the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI),funded by the Ministry of Health&Welfare,Republic of Korea(No.HR20C0026)the National Research Foundation of Korea(NRF)(No.RS-2023-00247504)the Patient-Centered Clinical Research Coordinating Center,funded by the Ministry of Health&Welfare,Republic of Korea(No.HC19C0276).
文摘AIM:To build a functional generalized estimating equation(GEE)model to detect glaucomatous visual field progression and compare the performance of the proposed method with that of commonly employed algorithms.METHODS:Totally 716 eyes of 716 patients with primary open angle glaucoma(POAG)with at least 5 reliable 24-2 test results and 2y of follow-up were selected.The functional GEE model was used to detect perimetric progression in the training dataset(501 eyes).In the testing dataset(215 eyes),progression was evaluated the functional GEE model,mean deviation(MD)and visual field index(VFI)rates of change,Advanced Glaucoma Intervention Study(AGIS)and Collaborative Initial Glaucoma Treatment Study(CIGTS)scores,and pointwise linear regression(PLR).RESULTS:The proposed method showed the highest proportion of eyes detected as progression(54.4%),followed by the VFI rate(34.4%),PLR(23.3%),and MD rate(21.4%).The CIGTS and AGIS scores had a lower proportion of eyes detected as progression(7.9%and 5.1%,respectively).The time to detection of progression was significantly shorter for the proposed method than that of other algorithms(adjusted P≤0.019).The VFI rate displayed moderate pairwise agreement with the proposed method(k=0.47).CONCLUSION:The functional GEE model shows the highest proportion of eyes detected as perimetric progression and the shortest time to detect perimetric progression in patients with POAG.
基金supported by the National Natural Science Foundation of China(Grant Nos.11972283 and 42277182).
文摘High-altitude cold regions exhibit complex geological and environmental conditions,fostering steep rock slopes with macroscopic joints and mesoscopic freeze-thaw(F-T)damage.Cyclic loading further exacerbates rock instability,yet the fracture mechanisms and load response relationships remain poorly understood.This study prepared intact and fractured sandstone specimens,subjected them to F-T cycles and graded loading-unloading,and monitored their structural evolution via X-ray computed tomography.First,the progressive failure process was investigated from both qualitative morphologic features and quantitative void parameters.The results showed that intact and fractured sandstone instability behaviors are determined by F-T damage and joint arrangement,respectively.However,both indicate that precursory localization of failure can only be detected when heterogeneous damage exists in advance.Furthermore,the void parameters of undamaged intact sandstone exhibit power-law acceleration,while damaged sandstones are characterized by a trend of initial decrease followed by an increase.Subsequently,a damage constitutive model for freeze-thawed fractured sandstone under graded loading-unloading was established.This model is based on the Lemaitre strain equivalence hypothesis and defines the coupled damage variable through multivariable indicators.In this framework,the material damage induced by fractures and F-T is unified and characterized by void parameters;while the load-induced damage is integrated with the energy linear allocation law and defined by damage energy.Thus,the stress-strain theoretical relationship is depicted,and the model is validated as reliable.Finally,a conceptual model of rock damage due to F-T and loading-unloading was proposed by combining the microscopic testing results from X-ray diffraction and scanning electron microscopy.
基金supported by the National Natural Science Foundation of China(Grants No.51579170 and 51179118)the Science Fund for Creative Research Groups of the National Natural Science Foundation of China(Grant No.51321065)
文摘Generally, most soil slope failures are induced by rainfall infiltration, a process that involves interactions between the liquid phase, gas phase,and solid skeleton in an unsaturated soil slope. In this study, a loosely coupled liquid-gas-solid three-phase model, linking two numerical codes,TOUGH2/EOS3, which is used for water-air two-phase flow analysis, and FLAC^(3D), which is used for mechanical analysis, was established. The model was validated through a documented water drainage experiment over a sandy column and a comparison of the results with measured data and simulated results from other researchers. The proposed model was used to investigate the features of water-air two-phase flow and stress fields in an unsaturated soil slope during rainfall infiltration. The slope stability analysis was then performed based on the simulated water-air two-phase seepage and stress fields on a given slip surface. The results show that the safety factor for the given slip surface decreases first, then increases, and later decreases until the rainfall stops. Subsequently, a sudden rise occurs. After that, the safety factor decreases continually and reaches its lowest value, and then increases slowly to a steady value. The lowest value does not occur when the rainfall stops, indicating a delayed effect of the safety factor. The variations of the safety factor for the given slip surface are therefore caused by a combination of pore-air pressure, matric suction, normal stress, and net normal stress.
基金Projected supported by the National Natural Science Foundation of China(Nos.11502123 and11262012)the Natural Science Foundation of Inner Mongolia Autonomous Region of China(No.2015JQ01)
文摘A three-phase confocal elliptical cylinder model is proposed to analyze micromechanics of one-dimensional hexagonal piezoelectric quasicrystal （PQC） compos- ites. Exact solutions of the phonon, phason, and electric fields are obtained by using the conformal mapping combined with the Laurent expansion technique when the model is subject to far-field anti-plane mechanical and in-plane electric loadings. The effective elec- troelastic constants of several different composites made up of PQC, quasicrystal （QC）, and piezoelectric （PE） materials are predicted by the generalized self-consistent method. Numerical examples are conducted to show the effects of the volume fraction and the cross-sectional shape of inclusion （or fiber） on the effective electroelastic constants of these composites. Compared with other micromechanical methods, the generalized self- consistent and Mori-Tanaka methods can predict the effective electroelastic constants of the composites consistently.
基金supported by the National Natural Science Foundation of China(Grant No.81371136)to X.Z.National Natural Science Foundation of China(Grant No.81771033)to L.Z
文摘Bone remodelling keeps going through the lifespan of human by bone formation and bone resorption.In the craniofacial region,mandibles act as the main force for biting and chewing,and also become susceptible to a common bone-loss disease,namely,apical periodontitis,once infected dental pulp is not treated timely,during which bone resorption occurs from the apical foramen to the apical bone area.Although conventional root canal treatment(RCT)can remove the most of the infection,chronical apical periodontitis due to incomplete removal of dental pulp and subsequent microleakage will become refractory and more challenging,and this process has scarcely been specifically studied as a bone remodelling issue in rat models.Therefore,to study chronical and refractory apical periodontitis owing to incomplete cleaning of infected dental pulp and microleackage in vivo,we establish a modified rat model of gradually progressive apical periodontitis by sealing residual necrotic dental pulp and introducing limited saliva,which simulates gradually progressive apical periodontitis,as observed in the clinical treatment of chronical and refractory apical periodontitis.We show that bone-loss is inevitable and progressive in this case of apical periodontitis,which confirms again that complete and sound root canal treatment is crucial to halt the progression of chronical and refractory apical periodontitis and promote bone formation.Interestingly,bone remodelling was enhanced at the initial stage of apical periodontitis in this model while reduced with a high osteoblast number afterwards,as shown by the time course study of the modified model.Suggesting that the pathological apical microenvironment reserve its hard tissue formation ability to some degree but in a disturbed manner.Hopefully,our findings can provide insights for future bone regenerative treatment for apical periodontitisassociated bone loss.
基金Sponsored by National Key Technology Research and Development Program in 11th Five-year Plan of China(2008AF33B01)Fuzhou University Foundation for Development of Science and Technology of China(0020-600588)
文摘By means of the computational fluid dynamics software Fluent 6.3, a mathematical model of three-dimensional three-phase fluid flow field in the molten bath of electric arc furnace （EAF） with side accessorial oxygen lances was developed to study the transient phenomena of oxygen jet impingement on the molten steel and the molten slag. The water modeling experiment was carried out to verify the simulation results. The impingement of the supersonic oxygen jet caused impact dent on the molten steel surface accordingly. The area of impact dent changed almost in linear relationship to flow rate of oxygen jet, which can be expressed by a deduced mathematical equation. And the relationship between the impact force of oxygen iet and the correspondingly formed apparent static pressure on molten bath was obtained, which was in linear relationship and a direct proportion, and can also be expressed by a deduced mathematical equation.
文摘A progressive micromechanical method is presented in order to predict the elastic constants of polydispersed composites including multi-directional or randomly ori- ented reinforcement particles. Heterogeneities of various types are introduced into the matrices in a gradual manner. At each step, the Mori-Tanaka method is used to ob- tain the stiffness tensor of the intermediate medium used as a matrix of the following step. The proposed method is capable of introducing any kind of heterogeneities based on their dimensions, orientations, mechanical properties, and volume fractions to the ma- trix. Furthermore, suitable probability density functions can be defined for physical and structural parameters of the composite, including the level of the filler-matrix interfacial bonding, the aspect ratio, and the orientation of reinforcement particles. The efficiency of the iterative approach and the convergence of the solution are studied by computing the stiffness tensors of unidirectional and bidirectional particulate composites. The results of the present study are also compared with the literature data for a randomly oriented particulate composite.
文摘The cooling channel process is a rehocasting method by which the prematerial with globular microstructure can be produced to fit the thixocasting process.A three-phase model based on volume averaging approach is proposed to simulate the cooling channel process of A356 Aluminum alloy.The three phases are liquid,solid and air respectively and treated as separated and interacting continua,sharing a single pressure field.The mass,momentum,enthalpy transport equations for each phase are solved.The developed model can predict the evolution of liquid,solid and air fraction as well as the distribution of grain density and grain size.The effect of pouring temperature on the grain density,grain size and solid fraction is analyzed in detail.
基金supported by the National Natural Science Foundation of China(Grant No.61271323)the Open Project from State Key Laboratory of MillimeterWaves,China(Grant No.K200913)
文摘Ultra-wideband （UWB） microwave imaging is a promising method for breast cancer detection based on the large contrast of electric parameters between the malignant tumor and its surrounded normal breast organisms. In the case of multiple tumors being present, the conventional imaging approaches may be ineffective to detect all the tumors clearly. In this paper, a progressive processing method is proposed for detecting more than one tumor. The method is divided into three stages： primary detection, refocusing and image optimization. To test the feasibility of the approach, a numerical breast model is developed based on the realistic magnetic resonance image （MRI）. Two tumors are assumed embedded in different positions. Successful detection of a 3.6 mm-diameter tumor at a depth of 42 mm is achieved. The correct information of both tumors is shown in the reconstructed image, suggesting that the progressive processing method is promising for multi-tumor detection.
文摘The present study aims at investigating the effect of temperature variation due to heat transfer between the formation and drilling fluids considering influx from the reservoir in the underbalanced drilling condition. Gas-liquid-solid three-phase flow model considering transient thermal interaction with the formation was applied to simulate wellbore fluid to calculate the wellbore temperature and pressure and analyze the influence of different parameters on fluid pressure and temperature distribution in annulus. The results show that the non-isothermal three-phase flow model with thermal consideration gives more accurate prediction of bottom-hole pressure(BHP) compared to other models considering geothermal temperature. Viscous dissipation, the heat produced by friction between the rotating drilling-string and well wall and drill bit drilling, and influx of oil and gas from reservoir have significant impact on the distribution of fluid temperature in the wellbore, which in turn affects the BHP. Bottom-hole fluid temperature decreases with increasing liquid flow rate, circulation time, and specific heat of liquid and gas but it increases with increasing in gas flow rate. It was found that BHP is strongly depended on the gas and liquid flow rates but it has weak dependence on the circulation time and specific heat of liquid and gas. BHP increase with increasing liquid flow rate and decreases with increasing gas flow rate.
基金supported by the National Natural Science Foundation of China under Grant 5227705。
文摘Finite-control-set model predictive control(FCSMPC)has advantages of multi-objective optimization and easy implementation.To reduce the computational burden and switching frequency,this article proposed a simplified MPC for dual three-phase permanent magnet synchronous motor(DTPPMSM).The novelty of this method is the decomposition of prediction function and the switching optimization algorithm.Based on the decomposition of prediction function,the current increment vector is obtained,which is employed to select the optimal voltage vector and calculate the duty cycle.Then,the computation burden can be reduced and the current tracking performance can be maintained.Additionally,the switching optimization algorithm was proposed to optimize the voltage vector action sequence,which results in lower switching frequency.Hence,this control strategy can not only reduce the computation burden and switching frequency,but also maintain the steady-state and dynamic performance.The simulation and experimental results are presented to verify the feasibility of the proposed strategy.
基金supported in part by National Natural Science Foundation of China(NSFC)under Project No.51737010in part by State Key Laboratory of Electrical Insulation and Power Equipment(EIPE19109)。
文摘The paper presents an accurate analytical subdomain model for predicting the electromagnetic performance in the symmetrical dual three-phase surface-mounted permanent magnet synchronous machine(PMSM)under open-phase faulty conditions.The model derivations are extended from previous accurate subdomain models accounting for slotting effects.Compared with most conventional subdomain models for traditional three-phase machines with nonoverlapping winding arrangement,the subdomain model proposed in this paper applied for the 24-slot/4-pole dual three-phase machine with symmetrical overlapping winding arrangement.In order to investigate the postfault electromagnetic performance,the reconfigured phase currents and then current density distribution in stator slots under different open-circuit conditions are discussed.According to the developed model and postfault current density distribution,the steady-state electromagnetic performance,such as the electromagnetic torque and unbalanced magnetic force,under open-circuit faulty conditions are obtained.For validation purposes,finite element analysis(FEA)is employed to validate the analytical results.The result indicate that the postfault electromagnet performance can be accurately predicted by the proposed subdomain model,which is in good agreement with FEA results.
基金supported by National Natural Science Foundation of China(No.81973713)。
文摘patients with PPF.TCM treatments are typically diverse and individualized,requiring urgent development of efficient and precise design strategies to identify effective treatment options.We designed an innovative Bayesian adaptive two-stage trial,hoping to provide new ideas for the rapid evaluation of the effectiveness of TCM in PPF.An open-label,two-stage,adaptive Bayesian randomized controlled trial will be conducted in China.Based on Bayesian methods,the trial will employ response-adaptive randomization to allocate patients to study groups based on data collected over the course of the trial.The adaptive Bayesian trial design will employ a Bayesian hierarchical model with“stopping”and“continuation”criteria once a predetermined posterior probability of superiority or futility and a decision threshold are reached.The trial can be implemented more efficiently by sharing the master protocol and organizational management mechanisms of the sub-trial we have implemented.The primary patient-reported outcome is a change in the Leicester Cough Questionnaire score,reflecting an improvement in cough-specific quality of life.The adaptive Bayesian trial design may be a promising method to facilitate the rapid clinical evaluation of TCM effectiveness for PPF,and will provide an example for how to evaluate TCM effectiveness in rare and refractory diseases.However,due to the complexity of the trial implementation,sufficient simulation analysis by professional statistical analysts is required to construct a Bayesian response-adaptive randomization procedure for timely response.Moreover,detailed standard operating procedures need to be developed to ensure the feasibility of the trial implementation.
基金supported by the Postdoctoral Science Foundation of the Power China Chengdu Engineering Corporation Limited(No.P66725)Science and Technology Fund Support Project of Power China Chengdu Engineering Corporation.(No.PA1717)。
文摘Landslides triggered by high gas pressure represent a distinct geotechnical hazard,especially in scenarios without significant rainfall.Recent studies have revealed that high-pressure gas accumulation within slopes can be a dominant trigger for large-scale failures although the processes behind this remain not well understood.This study examines how unsaturated soil slopes fail under high gas pressure using a combination of laboratory experiments and numerical simulations.A key discovery is that gas pressure changes slope stability by redistributing pore fluids and altering effective stress,with distinct depthdependent effects.Moreover,a novel concept of critical stable gas pressure(P_(ac))is proposed as a practical threshold for stability assessment,which is depthdependent,with extreme values at shallow and intermediate depths,reflecting the interplay between gas diffusion and overburden resistance.This study advances the mechanistic understanding of gasinduced slope instability and offers actionable benchmarks for managing related risks in engineering projects including waste landfill management and shale gas operations.
基金Project supported by the National Natural Science Foundation of China (Nos.10272047 and 10376046).
文摘The failure wave has been observed propagating in glass under impact loading since 1991. It is a continuous fracture zone which may be associated with the damage accumulation process during the propagation of shock waves. A progressive fracture model was proposed to describe the failure wave formation and propagation in shocked glass considering its heterogeneous meso-structures. The original and. nucleated microcracks will expand along the pores and other defects with concomitant dilation when shock loading is below the Hugoniot Elastic Limit. The governing equation of the failure wave is characterized by inelastic bulk strain with material damage and fracture. And the inelastic bulk strain consists of dilatant strain from nucleation and expansion of microcracks and condensed strain from the collapse of the original pores. Numerical simulation of the free surface velocity was performed and found in good agreement with planar impact experiments on K9 glass at China Academy of Engineering Physics. And the longitudinal, lateral and shear stress histories upon the arrival of the failure wave were predicted, which present the diminished shear strength and lost spall strength in the failed layer.
基金Project supported by the National Natural Science Foundation of China (Nos.10376046, 10272047) and the Defense Science Technology Key Lab Foundation of China (Nos.99JS75, 22JN2001)
文摘Polycrystalline ceramics have heterogeneous meso-structures which result in high singularity in stress distribution. Based on this, a progressive fragment model was proposed which describes the failure wave formation and propagation in shocked ceramics. The governing equation of the failure wave was characterized by inelastic bulk strain with material damage and fracture. And the inelastic bulk strain consists of dilatant strain from nucleation and expansion of microcracks and condensed strain from collapse of original pores. Numerical simulation of the free surface velocity was performed in good agreement with planar impact experiments on 92.93% aluminas at China Academy of Engineering Physics. And the longitudinal, lateral and shear stress histories upon the arrival of the failure wave were predicted, which present the diminished shear strength and lost spall strength in the failed layer.
基金supported by the National Key Research and Development Program of China under the grant of 2022YFB3403100。
文摘The dual three-phase PMSM(DTP-PMSM)drives have received wide attention at high-power high-efficiency applications due to their merits of high output current ability and copper-loss-free field excitation.Meanwhile,the DTPPMSM drive provides higher fault-tolerant capability for highreliability applications,e.g.,pumps and actuators in aircraft.For high-power drives with limited switching frequencies and highspeed drives with large fundamental frequencies,the ratio of switching frequency to fundamental frequency,i.e.,the carrier ratio,is usually below 15,which would significantly degrade the control performance.The purpose of this paper is to review the recent work on the modulation and control schemes for improving the operation performance of DTP-PMSM drives with low carrier ratios.Specifically,three categories of methods,i.e.,the space vector modulation based control,the model predictive control(MPC),and the optimized pulse pattern(OPP)based control are reviewed with principles and performance.In addition,brief discussions regarding the comparison and future trends are presented for low-carrier-ratio(LCR)modulation and control schemes of DTP-PMSM drives.
基金the National Natural Science Foundation of China(No.59635140)the Doctorate Foundation of Xi'an Jiaotong University
文摘An in-depth investigation is made on the problem of an arc-shapedinterface insulating crack in a three-phase concentric circularcylindrical piezoelectric composite constitutive model. An exactsolution in series form is derived by employing the complex variablemethod. In addition, the distribution of physical quantities such asstresses, strains, electric displacements and electric fields in thewhole field and along the interface is also presented.
基金Supported by the Fujian Provincial Education Council (No. JB9940).
文摘The axial concentration distribution of both particles with betterwetting (forming non-attached system) and poorer wetting (formingattached system) was investigated in a vertical gas-liquid-solidfluidized bed of 4.2 cm in diameters and 130 cm in height with thesolids holdup less than 0.05. The one-dimensionalsedimentation-dispersion model could be used satisfactorily todescribe the axial distribution of solids holdup by modifying only amodel parameter, i.e. by means of the terminal settling velocityminus a certain value, which is a functions of gas velocity andconsiders the effect of an additional drag force resulted fromattached rising bubbles.
