The failure mechanism of two-dimensional（2D） and three-dimensional（3D） slopes were investigated by using the strength reduction method.An extensive study of 3D effect was conducted with respect to boundary conditi...The failure mechanism of two-dimensional（2D） and three-dimensional（3D） slopes were investigated by using the strength reduction method.An extensive study of 3D effect was conducted with respect to boundary conditions,shear strength and concentrated surcharge load.The results obtained by 2D and 3D analyses were compared and the applicable scope of 2D and 3D method was analyzed.The results of the numerical simulation show that 3D effect is sensitive to the width of slip surface.As for slopes with specific geometry,3D effect is influenced by dimensionless parameter c/（γHtanφ）.For those infinite slopes with local loading,external load has the major impact on failure mode.For those slopes with local loading and geometric constraints,the failure mode is influenced by both factors.With the increase of loading length,boundary condition exerts a more significant impact on the failure mode,and then 2D and 3D stability charts are developed,which provides a rapid and reliable way to calculate 2D and 3D factor of safety without iteration.Finally,a simple and practical calculation procedure based on the study of 3D effect and stability charts is proposed to recognize the right time to apply 2D or 3D method.展开更多
Collapses of seismic slopes demonstrate the characteristics of three-dimensional(3D)shapes.Conducting a 3D analysis of seismic slope stability is more complicated than doing a simplified two-dimensional(2D)analysis.Th...Collapses of seismic slopes demonstrate the characteristics of three-dimensional(3D)shapes.Conducting a 3D analysis of seismic slope stability is more complicated than doing a simplified two-dimensional(2D)analysis.The upper-bound solutions derived from limit analysis of seismic slopes using the pseudo-static method are used to generate an approximate solution for the factor of 3D safety through regression analysis.Such a solution can degenerate to a 2D result when the slope width tends to infinity.The approximation method also can be extended for determining the permanent displacements of 3D slopes under seismic loading.The method is non-iterative and relatively accurate through comparisons with analytical results.Involving stochastic ground motions could easily be used to assess the distribution of permanent displacement that is induced in 3D slopes.展开更多
Probabilistic analysis is a rational approach for engineering design because it provides more insight than traditional deterministic analysis. Probabilistic evaluation on seismic stability of three dimensional (3D) sl...Probabilistic analysis is a rational approach for engineering design because it provides more insight than traditional deterministic analysis. Probabilistic evaluation on seismic stability of three dimensional (3D) slopes is studied in this paper. The slope safety factor is computed by combining the kinematic approach of limit analysis using a three-dimensional rotational failure mechanism with the pseudo-dynamic approach. The variability of input parameters, including six pseudo-dynamic parameters and two soil shear strength parameters, are taken into account by means of Monte-Carlo Simulations (MCS) method. The influences of pseudo-dynamic input variables on the computed failure probabilities are investigated and discussed. It is shown that the obtained failure probabilities increase with the pseudo-dynamic input variables and the pseudo-dynamic approach gives more conservative failure probability estimates compared with the pseudo-static approach.展开更多
In the reliability analysis of slope, the performance functions derived from the most available stability analysis procedures of slopes are usually implicit and cannot be solved by first-order second-moment approach. ...In the reliability analysis of slope, the performance functions derived from the most available stability analysis procedures of slopes are usually implicit and cannot be solved by first-order second-moment approach. A new reliability analysis approach was presented based on three-dimensional Morgenstem-Price method to investigate three-dimensional effect of landslide in stability analyses. To obtain the reliability index, Support Vector Machine （SVM） was applied to approximate the performance function. The time-consuming of this approach is only 0.028% of that using Monte-Carlo method at the same computation accuracy. Also, the influence of time effect of shearing strength parameters of slope soils on the long-term reliability of three-dimensional slopes was investigated by this new approach. It is found that the reliability index of the slope would decrease by 52.54% and the failure probability would increase from 0.000 705% to 1.966%. In the end, the impact of variation coefficients of c andfon reliability index of slopes was taken into discussion and the changing trend was observed.展开更多
The effects of nonlinearity of strength envelopes on 3D slope stability analysis are investigated.A power relation for the nonlinear envelope is employed to derive the 3D factor of safety equations of an extended Spen...The effects of nonlinearity of strength envelopes on 3D slope stability analysis are investigated.A power relation for the nonlinear envelope is employed to derive the 3D factor of safety equations of an extended Spencer method hich satisfies boty force equilibrium and moment equilibrium.Then,a search procedure is presented based on dynamic programming to determine the 3D critical slip surface for a general slope,Linear and nonlinear strength envelopes used for slope stability computations are obtained by fitting curves to the 103 strength data of consolidated-undrained(CU)triaxial compression tests for compacted Israeli clay.Results of a typical 3D problem show that a linear approximation of the nonlinear strength envelope may lead to a significant overestimation of calculated safety factors.展开更多
In existing studies, most slope stability analyses concentrate on conditions with constant temperature, assuming the slope is intact, and employ the Mohr-Coulomb (M-C) failure criterion for saturated soil to character...In existing studies, most slope stability analyses concentrate on conditions with constant temperature, assuming the slope is intact, and employ the Mohr-Coulomb (M-C) failure criterion for saturated soil to characterize the strength of the backfill. However, the actual working temperature of slopes varies, and natural phenomena such as rainfall and groundwater infiltration commonly result in unsaturated soil conditions, with cracks typically present in cohesive slopes. This study introduces a novel approach for assessing the stability of unsaturated soil stepped slopes under varying temperatures, incorporating the effects of open and vertical cracks. Utilizing the kinematic approach and gravity increase method, we developed a three-dimensional (3D) rotational wedge failure mechanism to simulate slope collapse, enhancing the traditional two-dimensional analyses. We integrated temperature-dependent functions and nonlinear shear strength equations to evaluate the impact of temperature on four typical unsaturated soil types. A particle swarm optimization algorithm was employed to calculate the safety factor, ensuring our method’s accuracy by comparing it with existing studies. The results indicate that considering 3D effects yields a higher safety factor, while cracks reduce slope stability. Each unsaturated soil exhibits a distinctive temperature response curve, highlighting the importance of understanding soil types in the design phase.展开更多
The parameters that influence slope stability and their criteria of failure are fairly understood but over-conservative design approaches are often preferred,which can result in excessive overburden removal that may j...The parameters that influence slope stability and their criteria of failure are fairly understood but over-conservative design approaches are often preferred,which can result in excessive overburden removal that may jeopardize profitability in the context of open pit mining.Numerical methods such as finite element and discrete element modelling are instrumental to identify specific zones of stability,but they remain approximate and do not pinpoint the critical factors that influence stability without extensive parametric studies.A large number of degrees of freedom and input parameters may make the outcome of numerical modelling insufficient compared to analytical solutions.Existing analytical approaches have not tackled the stability of slopes using non-linear plasticity criteria and threedimensional failure mechanisms.This paper bridges this gap by using the yield design theory and the Hoek-Brown criterion.Moreover,the proposed model includes the effect of seismic forces,which are not always taken into account in slope stability analyses.The results are presented in the form of rigorous mathematical expressions and stability charts involving the loading conditions and the rock mass properties emanating from the plasticity criterion.展开更多
Based on the assumption of the plain-strain problem, various optimization or random search methods have been developed for locating the critical slip surfaces in slope-stability analysis, but none of such methods is a...Based on the assumption of the plain-strain problem, various optimization or random search methods have been developed for locating the critical slip surfaces in slope-stability analysis, but none of such methods is applicable to the 3D case. In this paper, a simple Monte Carlo random simulation method is proposed to identify the 3D critical slip surface. Assuming the initial slip to be the lower part of a slip ellipsoid, the 3D critical slip surface is located by means of a minimized 3D safety factor. A column-based 3D slope stability analysis model is used to calculate this factor. In this study, some practical cases of known minimum safety factors and critical slip surfaces in 2D analysis are extended to 3D slope problems to locate the critical slip surfaces. Compared with the 2D result, the resulting 3D critical slip surface has no apparent difference in terms of only cross section, but the associated 3D safety factor is definitely higher.展开更多
Based on the upper bound of limit analysis, the plane-strain analysis of the slopes reinforced with a row of piles to the 3D case was extended. A 3D rotational failure mechanism was adopted to yield the upper bound of...Based on the upper bound of limit analysis, the plane-strain analysis of the slopes reinforced with a row of piles to the 3D case was extended. A 3D rotational failure mechanism was adopted to yield the upper bound of the factor of safety. Parametric studies were carried out to explore the end effects of the slope failures and the effects of the pile location and diameter on the safety of the reinforced slopes. The results demonstrate that the end effects nearly have no effects on the most suitable location of the installed piles but have significant influence on the safety of the slopes. For a slope constrained to a narrow width, the slope becomes more stable owing to the contribution of the end effects. When the slope is reinforced with a row of piles in small space between piles, the effects of group piles are significant for evaluating the safety of slopes. The presented method is more appropriate for assessing the stability of slopes reinforced with piles and can be also utilized in the design of plies stabilizing the unstable slopes.展开更多
The appearance of 3D laser scanning technology is one of the most important technology revolutions in surveying and mapping field. It can be widely used in many interrelated fields, such as engineering constructions a...The appearance of 3D laser scanning technology is one of the most important technology revolutions in surveying and mapping field. It can be widely used in many interrelated fields, such as engineering constructions and 3D measurements, owing to its prominent characteristics of the high efficiency and high precision. At present its application is still in the initial state, and it is quite rarely used in China, especially in geotechnical engineering and geological engineering fields. Starting with a general introduction of 3D laser scanning technology, this article studies how to apply the technology to high rock slope investigations. By way of a case study, principles and methods of quick slope documentation and occurrence measurement of discontinuities are discussed and analyzed. Analysis results show that the application of 3D laser scanning technology to geotechnical and geological engineering has a great prospect and value.展开更多
A method of three-dimensional loaded slope stability for anisotropic and nonhomogeneous slopes was presented based on the upper-bound theorem of the limit analysis approach. The approach can be considered as a modific...A method of three-dimensional loaded slope stability for anisotropic and nonhomogeneous slopes was presented based on the upper-bound theorem of the limit analysis approach. The approach can be considered as a modification and extension of the solutions. The influences of friction angle, anisotropy factor, nonhomogeneous factor, slope angle, ratio of width to depth, and load on the slope crest were investigated. The results show that solutions are suitable to deal with the purely cohesive soils and frictional/cohesive soils, isotropic and anisotropic, homogeneous and nonhomogeneous, loaded and unloaded cases.展开更多
A method of three-dimensional limited slope stability analysis is presented here based on the upperbound theorem of the limit analysis approach.A rotating collapse mechanism is considered in which energy dissipation t...A method of three-dimensional limited slope stability analysis is presented here based on the upperbound theorem of the limit analysis approach.A rotating collapse mechanism is considered in which energy dissipation takes place along curve velocity discontinuities.In the frictional soils,the failure surface has the shape of logarithm helicoids,with track outline defined by log-spirals.In the cohesive soils,the shape of the failure surface is torus.Angle is considered at slope top,and the critical height is less than top with no inclination.Numerical results of the proposed algorithm are presented in the form of nondimensional graphs.Some examples illustrate the practical use of the results.展开更多
Even Unzen volcano has been declared to be in a state of relative dormancy,the latest formed lava lobe No.11 now represents a potential slope failure mass based on the latest research.This paper concentrates on the st...Even Unzen volcano has been declared to be in a state of relative dormancy,the latest formed lava lobe No.11 now represents a potential slope failure mass based on the latest research.This paper concentrates on the stability of the lava lobe No.11 and its possible critical sliding mass.It proposes geographic information systems(GIS)based three-dimensional(3D)slope stability analysis models.It uses a 3D locating approach to identify the 3D critical slip surface and to analyze the 3D stability of the lava lobe No.11.At the same time,the new 3D approach shows the effectiveness in selecting the range of the Monte Carlo random variables and locating the critical slip surface in different parts of the lava lobe No.11.The results are very valuable for judging the stability of the lava lobe and assigning the monitoring equipments.展开更多
The 2D limit equilibrium method is widely used for slope stability analysis.However,with the advancement of dump engineering,composite slopes often exhibit significant 3D mechanical effects.Consequently,it is of signi...The 2D limit equilibrium method is widely used for slope stability analysis.However,with the advancement of dump engineering,composite slopes often exhibit significant 3D mechanical effects.Consequently,it is of significant importance to develop an effective 3D stability calculation method for composite slopes to enhance the design and stability control of open-pit slope engineering.Using the composite slope formed by the mining stope and inner dump in Baiyinhua No.1 and No.2 open-pit coal mine as a case study,this research investigates the failure mode of composite slopes and establishes spatial shape equations for the sliding mass.By integrating the shear resistance and sliding force of each row of microstrip columns onto the bottom surface of the strip corresponding to the main sliding surface,a novel 2D equivalent physical and mechanical parameters analysis method for the strips on the main sliding surface of 3D sliding masses is proposed.Subsequently,a comprehensive 3D stability calculation method for composite slopes is developed,and the quantitative relationship between the coordinated development distance and its 3D stability coefficients is examined.The analysis reveals that the failure mode of the composite slope is characterized by cutting-bedding sliding,with the arc serving as the side interface and the weak layer as the bottom interface,while the destabilization mechanism primarily involves shear failure.The spatial form equation of the sliding mass comprises an ellipsoid and weak plane equation.The analysis revealed that when the coordinated development distance is 1500 m,the error rate between the 3D stability calculation result and the 2D stability calculation result of the composite slope is less than 8%,thereby verifying the proposed analytical method of equivalent physical and mechanical parameters and the 3D stability calculation method for composite slopes.Furthermore,the3D stability coefficient of the composite slope exhibits an exponential correlation with the coordinated development distance,with the coefficient gradually decreasing as the coordinated development distance increases.These findings provide a theoretical guideline for designing similar slope shape parameters and conducting stability analysis.展开更多
0 INTRODUCTION.The classification of the rock mass quality is an important research topic within geological engineering and rock mechanics,because it is a powerful tool to perform rock mass stability analysis in rock ...0 INTRODUCTION.The classification of the rock mass quality is an important research topic within geological engineering and rock mechanics,because it is a powerful tool to perform rock mass stability analysis in rock engineering practices(Babacan et al.,2014;Singh et al.,1992).展开更多
Three-dimensional(3D)urban structures play a critical role in informing climate mitigation strategies aimed at the built environment and facilitating sustainable urban development.Regrettably,there exists a significan...Three-dimensional(3D)urban structures play a critical role in informing climate mitigation strategies aimed at the built environment and facilitating sustainable urban development.Regrettably,there exists a significant gap in detailed and consistent data on 3D building space structures with global coverage due to the challenges inherent in the data collection and model calibration processes.In this study,we constructed a global urban structure(GUS-3D)dataset,including building volume,height,and footprint information,at a 500 m spatial resolution using extensive satellite observation products and numerous reference building samples.Our analysis indicated that the total volume of buildings worldwide in2015 exceeded 1×10^(12)m^(3).Over the 1985 to 2015 period,we observed a slight increase in the magnitude of 3D building volume growth(i.e.,it increased from 166.02 km3 during the 1985–2000 period to 175.08km3 during the 2000–2015 period),while the expansion magnitudes of the two-dimensional(2D)building footprint(22.51×10^(3) vs 13.29×10^(3)km^(2))and urban extent(157×10^(3) vs 133.8×10^(3)km^(2))notably decreased.This trend highlights the significant increase in intensive vertical utilization of urban land.Furthermore,we identified significant heterogeneity in building space provision and inequality across cities worldwide.This inequality is particularly pronounced in many populous Asian cities,which has been overlooked in previous studies on economic inequality.The GUS-3D dataset shows great potential to deepen our understanding of the urban environment and creates new horizons for numerous 3D urban studies.展开更多
To address the problem of multi-missile cooperative interception against maneuvering targets at a prespecified impact time and desired Line-of-Sight(LOS)angles in ThreeDimensional(3D)space,this paper proposes a 3D lea...To address the problem of multi-missile cooperative interception against maneuvering targets at a prespecified impact time and desired Line-of-Sight(LOS)angles in ThreeDimensional(3D)space,this paper proposes a 3D leader-following cooperative interception guidance law.First,in the LOS direction of the leader,an impact time-controlled guidance law is derived based on the fixed-time stability theory,which enables the leader to complete the interception task at a prespecified impact time.Next,in the LOS direction of the followers,by introducing a time consensus tracking error function,a fixed-time consensus tracking guidance law is investigated to guarantee the consensus tracking convergence of the time-to-go.Then,in the direction normal to the LOS,by combining the designed global integral sliding mode surface and the second-order Sliding Mode Control(SMC)theory,an innovative 3D LOS-angle-constrained interception guidance law is developed,which eliminates the reaching phase in the traditional sliding mode guidance laws and effectively saves energy consumption.Moreover,it effectively suppresses the chattering phenomenon while avoiding the singularity issue,and compensates for unknown interference caused by target maneuvering online,making it convenient for practical engineering applications.Finally,theoretical proof analysis and multiple sets of numerical simulation results verify the effectiveness,superiority,and robustness of the investigated guidance law.展开更多
The influences of soil dilatancy angle on three-dimensional （3D） seismic stability of locally-loaded slopes in nonassociated flow rule materials were investigated using a new rotational collapse mechanism and quasi-...The influences of soil dilatancy angle on three-dimensional （3D） seismic stability of locally-loaded slopes in nonassociated flow rule materials were investigated using a new rotational collapse mechanism and quasi-static coefficient concept. Extended Bishop method and Boussinesq theorem were employed to establish the stress distribution along the rupture surfaces that are required to obtain the rate of internal energy dissipation for the nonassociated flow rule materials in rotational collapse mechanisms. Good agreement was observed by comparing the current results with those obtained using the translational or rotational mechanisms and numerical finite difference method. The results indicate that the seismic stability of slopes reduces by decreasing the dilatancy angle for nonassociated flow rule materials. The amount of the mentioned decrease is more significant in the case of mild slopes in frictional soils. A nearly infinite slope under local loading, whether its critical failure surface is 2D or 3D, not only depends on the magnitude of the external load, but also depends on the dilataney angle of soil and the coefficient of seismic load.展开更多
Liposarcoma is one of the most common soft tissue sarcomas,however,its occurrence rate is still rare compared to other cancers.Due to its rarity,in vitro experiments are an essential approach to elucidate liposarcoma ...Liposarcoma is one of the most common soft tissue sarcomas,however,its occurrence rate is still rare compared to other cancers.Due to its rarity,in vitro experiments are an essential approach to elucidate liposarcoma pathobiology.Conventional cell culture-based research(2D cell culture)is still playing a pivotal role,while several shortcomings have been recently under discussion.In vivo,mouse models are usually adopted for pre-clinical analyses with expectations to overcome the issues of 2D cell culture.However,they do not fully recapitulate human dedifferentiated liposarcoma(DDLPS)characteristics.Therefore,three-dimensional(3D)culture systems have been the recent research focus in the cell biology field with the expectation to overcome at the same time the disadvantages of 2D cell culture and in vivo animal models and fill in the gap between them.Given the liposarcoma rarity,we believe that 3D cell culture techniques,including 3D cell cultures/co-cultures,and Patient-Derived tumor Organoids(PDOs),represent a promising approach to facilitate liposarcoma investigation and elucidate its molecular mechanisms and effective therapy development.In this review,we first provide a general overview of 3D cell cultures compared to 2D cell cultures.We then focus on one of the recent 3D cell culture applications,Patient-Derived Organoids(PDOs),summarizing and discussing several PDO methodologies.Finally,we discuss the current and future applications of PDOs to sarcoma,particularly in the field of liposarcoma.展开更多
Bone repair remains an important target in tissue engineering,making the development of bioactive scaffolds for effective bone defect repair a critical objective.In this study,β-tricalcium phosphate(β-TCP)scaffolds ...Bone repair remains an important target in tissue engineering,making the development of bioactive scaffolds for effective bone defect repair a critical objective.In this study,β-tricalcium phosphate(β-TCP)scaffolds incorporated with processed pyritum decoction(PPD)were fabricated using three-dimensional(3D)printing-assisted freeze-casting.The produced composite scaffolds were evaluated for their mechanical strength,physicochemical properties,biocompatibility,in vitro proangiogenic activity,and in vivo efficacy in repairing rabbit femoral defects.They not only demonstrated excellent physicochemical properties,enhanced mechanical strength,and good biosafety but also significantly promoted the proliferation,migration,and aggregation of pro-angiogenic human umbilical vein endothelial cells(HUVECs).In vivo studies revealed that all scaffold groups facilitated osteogenesis at the bone defect site,with theβ-TCP scaffolds loaded with PPD markedly enhancing the expression of neurogenic locus Notch homolog protein 1(Notch1),vascular endothelial growth factor(VEGF),bone morphogenetic protein-2(BMP-2),and osteopontin(OPN).Overall,the scaffolds developed in this study exhibited strong angiogenic and osteogenic capabilities both in vitro and in vivo.The incorporation of PPD notably promoted the angiogenic-osteogenic coupling,thereby accelerating bone repair,which suggests that PPD is a promising material for bone repair and that the PPD/β-TCP scaffolds hold great potential as a bone graft alternative.展开更多
基金Project (10972238) supported by the National Natural Science Foundation of ChinaProject (2010ssxt237) supported by the Excellent Doctoral Thesis Program of Central South University,China
文摘The failure mechanism of two-dimensional（2D） and three-dimensional（3D） slopes were investigated by using the strength reduction method.An extensive study of 3D effect was conducted with respect to boundary conditions,shear strength and concentrated surcharge load.The results obtained by 2D and 3D analyses were compared and the applicable scope of 2D and 3D method was analyzed.The results of the numerical simulation show that 3D effect is sensitive to the width of slip surface.As for slopes with specific geometry,3D effect is influenced by dimensionless parameter c/（γHtanφ）.For those infinite slopes with local loading,external load has the major impact on failure mode.For those slopes with local loading and geometric constraints,the failure mode is influenced by both factors.With the increase of loading length,boundary condition exerts a more significant impact on the failure mode,and then 2D and 3D stability charts are developed,which provides a rapid and reliable way to calculate 2D and 3D factor of safety without iteration.Finally,a simple and practical calculation procedure based on the study of 3D effect and stability charts is proposed to recognize the right time to apply 2D or 3D method.
基金National Natural Science Foundation of China under Grant No.52322808the Fundamental Research Funds for the Central Universities under Grant No.B220202013。
文摘Collapses of seismic slopes demonstrate the characteristics of three-dimensional(3D)shapes.Conducting a 3D analysis of seismic slope stability is more complicated than doing a simplified two-dimensional(2D)analysis.The upper-bound solutions derived from limit analysis of seismic slopes using the pseudo-static method are used to generate an approximate solution for the factor of 3D safety through regression analysis.Such a solution can degenerate to a 2D result when the slope width tends to infinity.The approximation method also can be extended for determining the permanent displacements of 3D slopes under seismic loading.The method is non-iterative and relatively accurate through comparisons with analytical results.Involving stochastic ground motions could easily be used to assess the distribution of permanent displacement that is induced in 3D slopes.
文摘Probabilistic analysis is a rational approach for engineering design because it provides more insight than traditional deterministic analysis. Probabilistic evaluation on seismic stability of three dimensional (3D) slopes is studied in this paper. The slope safety factor is computed by combining the kinematic approach of limit analysis using a three-dimensional rotational failure mechanism with the pseudo-dynamic approach. The variability of input parameters, including six pseudo-dynamic parameters and two soil shear strength parameters, are taken into account by means of Monte-Carlo Simulations (MCS) method. The influences of pseudo-dynamic input variables on the computed failure probabilities are investigated and discussed. It is shown that the obtained failure probabilities increase with the pseudo-dynamic input variables and the pseudo-dynamic approach gives more conservative failure probability estimates compared with the pseudo-static approach.
基金Project(50878082) supported by the National Natural Science Foundation of ChinaProject(200631880237) supported by the Science and Technology Program of West Transportation of the Ministry of Transportation of ChinaKey Project(09JJ3104) supported by the Natural Science Foundation of Hunan Province, China
文摘In the reliability analysis of slope, the performance functions derived from the most available stability analysis procedures of slopes are usually implicit and cannot be solved by first-order second-moment approach. A new reliability analysis approach was presented based on three-dimensional Morgenstem-Price method to investigate three-dimensional effect of landslide in stability analyses. To obtain the reliability index, Support Vector Machine （SVM） was applied to approximate the performance function. The time-consuming of this approach is only 0.028% of that using Monte-Carlo method at the same computation accuracy. Also, the influence of time effect of shearing strength parameters of slope soils on the long-term reliability of three-dimensional slopes was investigated by this new approach. It is found that the reliability index of the slope would decrease by 52.54% and the failure probability would increase from 0.000 705% to 1.966%. In the end, the impact of variation coefficients of c andfon reliability index of slopes was taken into discussion and the changing trend was observed.
文摘The effects of nonlinearity of strength envelopes on 3D slope stability analysis are investigated.A power relation for the nonlinear envelope is employed to derive the 3D factor of safety equations of an extended Spencer method hich satisfies boty force equilibrium and moment equilibrium.Then,a search procedure is presented based on dynamic programming to determine the 3D critical slip surface for a general slope,Linear and nonlinear strength envelopes used for slope stability computations are obtained by fitting curves to the 103 strength data of consolidated-undrained(CU)triaxial compression tests for compacted Israeli clay.Results of a typical 3D problem show that a linear approximation of the nonlinear strength envelope may lead to a significant overestimation of calculated safety factors.
基金Project(51378510) supported by the National Natural Science Foundation of China。
文摘In existing studies, most slope stability analyses concentrate on conditions with constant temperature, assuming the slope is intact, and employ the Mohr-Coulomb (M-C) failure criterion for saturated soil to characterize the strength of the backfill. However, the actual working temperature of slopes varies, and natural phenomena such as rainfall and groundwater infiltration commonly result in unsaturated soil conditions, with cracks typically present in cohesive slopes. This study introduces a novel approach for assessing the stability of unsaturated soil stepped slopes under varying temperatures, incorporating the effects of open and vertical cracks. Utilizing the kinematic approach and gravity increase method, we developed a three-dimensional (3D) rotational wedge failure mechanism to simulate slope collapse, enhancing the traditional two-dimensional analyses. We integrated temperature-dependent functions and nonlinear shear strength equations to evaluate the impact of temperature on four typical unsaturated soil types. A particle swarm optimization algorithm was employed to calculate the safety factor, ensuring our method’s accuracy by comparing it with existing studies. The results indicate that considering 3D effects yields a higher safety factor, while cracks reduce slope stability. Each unsaturated soil exhibits a distinctive temperature response curve, highlighting the importance of understanding soil types in the design phase.
文摘The parameters that influence slope stability and their criteria of failure are fairly understood but over-conservative design approaches are often preferred,which can result in excessive overburden removal that may jeopardize profitability in the context of open pit mining.Numerical methods such as finite element and discrete element modelling are instrumental to identify specific zones of stability,but they remain approximate and do not pinpoint the critical factors that influence stability without extensive parametric studies.A large number of degrees of freedom and input parameters may make the outcome of numerical modelling insufficient compared to analytical solutions.Existing analytical approaches have not tackled the stability of slopes using non-linear plasticity criteria and threedimensional failure mechanisms.This paper bridges this gap by using the yield design theory and the Hoek-Brown criterion.Moreover,the proposed model includes the effect of seismic forces,which are not always taken into account in slope stability analyses.The results are presented in the form of rigorous mathematical expressions and stability charts involving the loading conditions and the rock mass properties emanating from the plasticity criterion.
文摘Based on the assumption of the plain-strain problem, various optimization or random search methods have been developed for locating the critical slip surfaces in slope-stability analysis, but none of such methods is applicable to the 3D case. In this paper, a simple Monte Carlo random simulation method is proposed to identify the 3D critical slip surface. Assuming the initial slip to be the lower part of a slip ellipsoid, the 3D critical slip surface is located by means of a minimized 3D safety factor. A column-based 3D slope stability analysis model is used to calculate this factor. In this study, some practical cases of known minimum safety factors and critical slip surfaces in 2D analysis are extended to 3D slope problems to locate the critical slip surfaces. Compared with the 2D result, the resulting 3D critical slip surface has no apparent difference in terms of only cross section, but the associated 3D safety factor is definitely higher.
基金Projects(51278382,51479050)supported by the National Natural Science Foundation of ChinaProject(2015CB057901)supported by the National Key Basic Research Program of China+3 种基金Project(201501035-03)supported by the Public Service Sector R&D Project of Ministry of Water Resource of ChinaProject(2014B06814)supported by the Fundamental Research Funds for the Central Universities,ChinaProject(B13024)supported by the"111"ProjectProject(YK913004)supported by the Open Foundation of Key Laboratory of Failure Mechanism and Safety Control Techniques of Earthrock Dam of the Ministry of Water Resources,China
文摘Based on the upper bound of limit analysis, the plane-strain analysis of the slopes reinforced with a row of piles to the 3D case was extended. A 3D rotational failure mechanism was adopted to yield the upper bound of the factor of safety. Parametric studies were carried out to explore the end effects of the slope failures and the effects of the pile location and diameter on the safety of the reinforced slopes. The results demonstrate that the end effects nearly have no effects on the most suitable location of the installed piles but have significant influence on the safety of the slopes. For a slope constrained to a narrow width, the slope becomes more stable owing to the contribution of the end effects. When the slope is reinforced with a row of piles in small space between piles, the effects of group piles are significant for evaluating the safety of slopes. The presented method is more appropriate for assessing the stability of slopes reinforced with piles and can be also utilized in the design of plies stabilizing the unstable slopes.
基金the Key Project of Joint Funds of Yalongjiang River Development of the National Natural Science Foundation of China (No. 50539050)
文摘The appearance of 3D laser scanning technology is one of the most important technology revolutions in surveying and mapping field. It can be widely used in many interrelated fields, such as engineering constructions and 3D measurements, owing to its prominent characteristics of the high efficiency and high precision. At present its application is still in the initial state, and it is quite rarely used in China, especially in geotechnical engineering and geological engineering fields. Starting with a general introduction of 3D laser scanning technology, this article studies how to apply the technology to high rock slope investigations. By way of a case study, principles and methods of quick slope documentation and occurrence measurement of discontinuities are discussed and analyzed. Analysis results show that the application of 3D laser scanning technology to geotechnical and geological engineering has a great prospect and value.
基金Projects(41002095,41172251,41272317) supported by the National Natural Science Foundation of China
文摘A method of three-dimensional loaded slope stability for anisotropic and nonhomogeneous slopes was presented based on the upper-bound theorem of the limit analysis approach. The approach can be considered as a modification and extension of the solutions. The influences of friction angle, anisotropy factor, nonhomogeneous factor, slope angle, ratio of width to depth, and load on the slope crest were investigated. The results show that solutions are suitable to deal with the purely cohesive soils and frictional/cohesive soils, isotropic and anisotropic, homogeneous and nonhomogeneous, loaded and unloaded cases.
基金the National Natural Science Foundation of China(Nos.41172251 and 41002095)
文摘A method of three-dimensional limited slope stability analysis is presented here based on the upperbound theorem of the limit analysis approach.A rotating collapse mechanism is considered in which energy dissipation takes place along curve velocity discontinuities.In the frictional soils,the failure surface has the shape of logarithm helicoids,with track outline defined by log-spirals.In the cohesive soils,the shape of the failure surface is torus.Angle is considered at slope top,and the critical height is less than top with no inclination.Numerical results of the proposed algorithm are presented in the form of nondimensional graphs.Some examples illustrate the practical use of the results.
基金Supported by the National Natural Science Foundation of China(40972229)provided by JSPS and Sabo Technical Center,Japan
文摘Even Unzen volcano has been declared to be in a state of relative dormancy,the latest formed lava lobe No.11 now represents a potential slope failure mass based on the latest research.This paper concentrates on the stability of the lava lobe No.11 and its possible critical sliding mass.It proposes geographic information systems(GIS)based three-dimensional(3D)slope stability analysis models.It uses a 3D locating approach to identify the 3D critical slip surface and to analyze the 3D stability of the lava lobe No.11.At the same time,the new 3D approach shows the effectiveness in selecting the range of the Monte Carlo random variables and locating the critical slip surface in different parts of the lava lobe No.11.The results are very valuable for judging the stability of the lava lobe and assigning the monitoring equipments.
基金supported by the National Natural Science Foundation of China (No.52374124)National Youth Science Foundation of China (No.52204135)+3 种基金Xing Liao Talent Plan (No.XLYC2202004)Young Elite Scientists Sponsorship Program by CAST (No.2023QNRC001)Liaoning Province International Science and Technology Cooperation Plan (No.2022JH2/1070004)Liaoning Natural Science Foundation Program (No.2022-BS-327)。
文摘The 2D limit equilibrium method is widely used for slope stability analysis.However,with the advancement of dump engineering,composite slopes often exhibit significant 3D mechanical effects.Consequently,it is of significant importance to develop an effective 3D stability calculation method for composite slopes to enhance the design and stability control of open-pit slope engineering.Using the composite slope formed by the mining stope and inner dump in Baiyinhua No.1 and No.2 open-pit coal mine as a case study,this research investigates the failure mode of composite slopes and establishes spatial shape equations for the sliding mass.By integrating the shear resistance and sliding force of each row of microstrip columns onto the bottom surface of the strip corresponding to the main sliding surface,a novel 2D equivalent physical and mechanical parameters analysis method for the strips on the main sliding surface of 3D sliding masses is proposed.Subsequently,a comprehensive 3D stability calculation method for composite slopes is developed,and the quantitative relationship between the coordinated development distance and its 3D stability coefficients is examined.The analysis reveals that the failure mode of the composite slope is characterized by cutting-bedding sliding,with the arc serving as the side interface and the weak layer as the bottom interface,while the destabilization mechanism primarily involves shear failure.The spatial form equation of the sliding mass comprises an ellipsoid and weak plane equation.The analysis revealed that when the coordinated development distance is 1500 m,the error rate between the 3D stability calculation result and the 2D stability calculation result of the composite slope is less than 8%,thereby verifying the proposed analytical method of equivalent physical and mechanical parameters and the 3D stability calculation method for composite slopes.Furthermore,the3D stability coefficient of the composite slope exhibits an exponential correlation with the coordinated development distance,with the coefficient gradually decreasing as the coordinated development distance increases.These findings provide a theoretical guideline for designing similar slope shape parameters and conducting stability analysis.
基金supported by the National Key R&D Program of China(No.2023YFC3081200)the National Natural Science Foundation of China(No.42077264)the Science and Technology Project of PowerChina Huadong Engineering(Fujian)Co.,Ltd.(No.HDEC-2022-0301).
文摘0 INTRODUCTION.The classification of the rock mass quality is an important research topic within geological engineering and rock mechanics,because it is a powerful tool to perform rock mass stability analysis in rock engineering practices(Babacan et al.,2014;Singh et al.,1992).
基金supported by the National Science Fund for Distinguished Young Scholars(42225107)the National Natural Science Foundation of China(42001326,42371414,42171409,and 42271419)+1 种基金the Natural Science Foundation of Guangdong Province of China(2022A1515012207)the Basic and Applied Basic Research Project of Guangzhou Science and Technology Planning(202201011539)。
文摘Three-dimensional(3D)urban structures play a critical role in informing climate mitigation strategies aimed at the built environment and facilitating sustainable urban development.Regrettably,there exists a significant gap in detailed and consistent data on 3D building space structures with global coverage due to the challenges inherent in the data collection and model calibration processes.In this study,we constructed a global urban structure(GUS-3D)dataset,including building volume,height,and footprint information,at a 500 m spatial resolution using extensive satellite observation products and numerous reference building samples.Our analysis indicated that the total volume of buildings worldwide in2015 exceeded 1×10^(12)m^(3).Over the 1985 to 2015 period,we observed a slight increase in the magnitude of 3D building volume growth(i.e.,it increased from 166.02 km3 during the 1985–2000 period to 175.08km3 during the 2000–2015 period),while the expansion magnitudes of the two-dimensional(2D)building footprint(22.51×10^(3) vs 13.29×10^(3)km^(2))and urban extent(157×10^(3) vs 133.8×10^(3)km^(2))notably decreased.This trend highlights the significant increase in intensive vertical utilization of urban land.Furthermore,we identified significant heterogeneity in building space provision and inequality across cities worldwide.This inequality is particularly pronounced in many populous Asian cities,which has been overlooked in previous studies on economic inequality.The GUS-3D dataset shows great potential to deepen our understanding of the urban environment and creates new horizons for numerous 3D urban studies.
文摘To address the problem of multi-missile cooperative interception against maneuvering targets at a prespecified impact time and desired Line-of-Sight(LOS)angles in ThreeDimensional(3D)space,this paper proposes a 3D leader-following cooperative interception guidance law.First,in the LOS direction of the leader,an impact time-controlled guidance law is derived based on the fixed-time stability theory,which enables the leader to complete the interception task at a prespecified impact time.Next,in the LOS direction of the followers,by introducing a time consensus tracking error function,a fixed-time consensus tracking guidance law is investigated to guarantee the consensus tracking convergence of the time-to-go.Then,in the direction normal to the LOS,by combining the designed global integral sliding mode surface and the second-order Sliding Mode Control(SMC)theory,an innovative 3D LOS-angle-constrained interception guidance law is developed,which eliminates the reaching phase in the traditional sliding mode guidance laws and effectively saves energy consumption.Moreover,it effectively suppresses the chattering phenomenon while avoiding the singularity issue,and compensates for unknown interference caused by target maneuvering online,making it convenient for practical engineering applications.Finally,theoretical proof analysis and multiple sets of numerical simulation results verify the effectiveness,superiority,and robustness of the investigated guidance law.
文摘The influences of soil dilatancy angle on three-dimensional （3D） seismic stability of locally-loaded slopes in nonassociated flow rule materials were investigated using a new rotational collapse mechanism and quasi-static coefficient concept. Extended Bishop method and Boussinesq theorem were employed to establish the stress distribution along the rupture surfaces that are required to obtain the rate of internal energy dissipation for the nonassociated flow rule materials in rotational collapse mechanisms. Good agreement was observed by comparing the current results with those obtained using the translational or rotational mechanisms and numerical finite difference method. The results indicate that the seismic stability of slopes reduces by decreasing the dilatancy angle for nonassociated flow rule materials. The amount of the mentioned decrease is more significant in the case of mild slopes in frictional soils. A nearly infinite slope under local loading, whether its critical failure surface is 2D or 3D, not only depends on the magnitude of the external load, but also depends on the dilataney angle of soil and the coefficient of seismic load.
文摘Liposarcoma is one of the most common soft tissue sarcomas,however,its occurrence rate is still rare compared to other cancers.Due to its rarity,in vitro experiments are an essential approach to elucidate liposarcoma pathobiology.Conventional cell culture-based research(2D cell culture)is still playing a pivotal role,while several shortcomings have been recently under discussion.In vivo,mouse models are usually adopted for pre-clinical analyses with expectations to overcome the issues of 2D cell culture.However,they do not fully recapitulate human dedifferentiated liposarcoma(DDLPS)characteristics.Therefore,three-dimensional(3D)culture systems have been the recent research focus in the cell biology field with the expectation to overcome at the same time the disadvantages of 2D cell culture and in vivo animal models and fill in the gap between them.Given the liposarcoma rarity,we believe that 3D cell culture techniques,including 3D cell cultures/co-cultures,and Patient-Derived tumor Organoids(PDOs),represent a promising approach to facilitate liposarcoma investigation and elucidate its molecular mechanisms and effective therapy development.In this review,we first provide a general overview of 3D cell cultures compared to 2D cell cultures.We then focus on one of the recent 3D cell culture applications,Patient-Derived Organoids(PDOs),summarizing and discussing several PDO methodologies.Finally,we discuss the current and future applications of PDOs to sarcoma,particularly in the field of liposarcoma.
基金supported by the National Science Foundation of China(Nos.81373970,81773902,81973484,and 32171402)the National College Students Innovation and Entrepreneurship Training Program(No.201810315019)+4 种基金the Postgraduate Research and Practice Innovation Program of Jiangsu Province(Nos.SJCX21_0712 and KYCX23_2052)the Scientific Research Project of Jiangsu Provincial Association of Traditional Chinese Medicine(No.XYLD2024013)the Youth Scientific Research Project of Jiangyin Municipal Health Commission(No.Q202402)the Natural Science Foundation Project of Nanjing University of Chinese Medicine(No.XZR2024173)the Jiangyin Science and Technology Innovation Special Fund Project(No.JY0603A011014230032PB),China.
文摘Bone repair remains an important target in tissue engineering,making the development of bioactive scaffolds for effective bone defect repair a critical objective.In this study,β-tricalcium phosphate(β-TCP)scaffolds incorporated with processed pyritum decoction(PPD)were fabricated using three-dimensional(3D)printing-assisted freeze-casting.The produced composite scaffolds were evaluated for their mechanical strength,physicochemical properties,biocompatibility,in vitro proangiogenic activity,and in vivo efficacy in repairing rabbit femoral defects.They not only demonstrated excellent physicochemical properties,enhanced mechanical strength,and good biosafety but also significantly promoted the proliferation,migration,and aggregation of pro-angiogenic human umbilical vein endothelial cells(HUVECs).In vivo studies revealed that all scaffold groups facilitated osteogenesis at the bone defect site,with theβ-TCP scaffolds loaded with PPD markedly enhancing the expression of neurogenic locus Notch homolog protein 1(Notch1),vascular endothelial growth factor(VEGF),bone morphogenetic protein-2(BMP-2),and osteopontin(OPN).Overall,the scaffolds developed in this study exhibited strong angiogenic and osteogenic capabilities both in vitro and in vivo.The incorporation of PPD notably promoted the angiogenic-osteogenic coupling,thereby accelerating bone repair,which suggests that PPD is a promising material for bone repair and that the PPD/β-TCP scaffolds hold great potential as a bone graft alternative.
