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Challenges and overcoming strategies in CAR-T cell therapy for pediatric neuroblastoma
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作者 Pei-Ting Ying Yong-Min Tang 《World Journal of Pediatrics》 2025年第2期123-130,共8页
Solid tumors account for more than 60%of all the pediatric malignancies and contribute substantially to the disease burden in China[1].Currently,there are five primary treatment strategies:surgery,radiation therapy,co... Solid tumors account for more than 60%of all the pediatric malignancies and contribute substantially to the disease burden in China[1].Currently,there are five primary treatment strategies:surgery,radiation therapy,conventional chemotherapy,molecular targeted agents and immunotherapy.While the first three methods are nearing their potential limits,the latter two are advancing rapidly,with new approaches continually emerging and resulting in positive clinical outcomes. 展开更多
关键词 treatment strategies pediatric malignancies CHALLENGES pediatric neuroblastoma CAR T cell therapy treatment strategies surgeryradiation therapyconventional chemotherapymolecular targeted agents STRATEGIES solid tumors
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