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Exploring the Abnormal Brain Regions and Abnormal Functional Connections in SZ by Multiple Hypothesis Testing Technique
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作者 Lan Yang Shun Qi +1 位作者 Chen Qiao Yanmei Kang 《Computer Modeling in Engineering & Sciences》 SCIE EI 2020年第10期215-237,共23页
Schizophrenia(SZ)is one of the most common mental diseases.Its main characteristics are abnormal social behavior and inability to correctly understand real things.In recent years,the magnetic resonance imaging(MRI)tec... Schizophrenia(SZ)is one of the most common mental diseases.Its main characteristics are abnormal social behavior and inability to correctly understand real things.In recent years,the magnetic resonance imaging(MRI)technique has been popularly utilized to study SZ.However,it is still a great challenge to reveal the essential information contained in the MRI data.In this paper,we proposed a biomarker selection approach based on the multiple hypothesis testing techniques to explore the difference between SZ and healthy controls by using both functional and structural MRI data,in which biomarkers represent both abnormal brain functional connectivity and abnormal brain regions.By implementing the biomarker selection approach,six abnormal brain regions and twenty-three abnormal functional connectivity in the brains of SZ are explored.It is discovered that compared with healthy controls,the significantly reduced gray matter volumes are mainly distributed in the limbic lobe and the basal ganglia,and the significantly increased gray matter volumes are distributed in the frontal gyrus.Meanwhile,it is revealed that the significantly strengthened connections are those between the middle frontal gyrus and the superior occipital gyrus,the superior occipital gyrus and the middle occipital gyrus as well as the middle occipital gyrus and the fusiform gyrus,and the rest connections are significantly weakened. 展开更多
关键词 Multiple hypothesis testing SCHIZOPHRENIA magnetic resonance imaging abnormal brain regions abnormal functional connectivity
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A New Deghosting Algorithm with Hypothesis Testing Data Fusion
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作者 唐小明 何友 王国宏 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2003年第2期14-19,共6页
Eliminating the false intersection (deghosting) is a difficult problem in a passive cross location system. Using a decentralized decision fusion topology, a new deghosting algorithm derived from hypothesis testing the... Eliminating the false intersection (deghosting) is a difficult problem in a passive cross location system. Using a decentralized decision fusion topology, a new deghosting algorithm derived from hypothesis testing theory is developed. It uses the difference between ghosts and true targets in the statistical error, which occurs between their projection angles on a deghosting sensor and is measured from a deghosting sensor, and constructs a corresponding test statistic. Under the Gaussian assumption, ghosts and true targets are decided and discriminated by Chi-square distribution. Simulation results show the feasibility of the algorithm. 展开更多
关键词 Deghosting hypothesis testing Decentralized decision fusion.
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Hypothesis Testing of Population Percentiles via the Wald Test with Bootstrap Variance Estimates
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作者 William D. Johnson Jacob E. Romer 《Open Journal of Statistics》 2016年第1期14-24,共11页
Testing the equality of percentiles (quantiles) between populations is an effective method for robust, nonparametric comparison, especially when the distributions are asymmetric or irregularly shaped. Unlike global no... Testing the equality of percentiles (quantiles) between populations is an effective method for robust, nonparametric comparison, especially when the distributions are asymmetric or irregularly shaped. Unlike global nonparametric tests for homogeneity such as the Kolmogorv-Smirnov test, testing the equality of a set of percentiles (i.e., a percentile profile) yields an estimate of the location and extent of the differences between the populations along the entire domain. The Wald test using bootstrap estimates of variance of the order statistics provides a unified method for hypothesis testing of functions of the population percentiles. Simulation studies are conducted to show performance of the method under various scenarios and to give suggestions on its use. Several examples are given to illustrate some useful applications to real data. 展开更多
关键词 BOOTSTRAP hypothesis testing Nonparametric Methods Percentile Profiles Wald Test
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Sensitivity and Specificity Analysis Relation to Statistical Hypothesis Testing and Its Errors: Application to Cryptosporidium Detection Techniques
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作者 Emmanuel de-Graft Johnson Owusu-Ansah Angelina Sampson +1 位作者 Amponsah K. Samuel Abaidoo Robert 《Open Journal of Applied Sciences》 2016年第4期209-216,共8页
The use of Statistical Hypothesis Testing procedure to determine type I and type II errors was linked to the measurement of sensitivity and specificity in clinical trial test and experimental pathogen detection techni... The use of Statistical Hypothesis Testing procedure to determine type I and type II errors was linked to the measurement of sensitivity and specificity in clinical trial test and experimental pathogen detection techniques. A theoretical analysis of establishing these types of errors was made and compared to determination of False Positive, False Negative, True Positive and True Negative. Experimental laboratory detection methods used to detect Cryptosporidium spp. were used to highlight the relationship between hypothesis testing, sensitivity, specificity and predicted values. The study finds that, sensitivity and specificity for the two laboratory methods used for Cryptosporidium detection were low hence lowering the probability of detecting a “false null hypothesis” for the presence of cryptosporidium in the water samples using either Microscopic or PCR. Nevertheless, both procedures for cryptosporidium detection had higher “true negatives” increasing its probability of failing to reject a “true null hypothesis” with specificity of 1.00 for both Microscopic and PCR laboratory detection methods. 展开更多
关键词 Sensitivity SPECIFICITY Type I and II Errors Detection Methods hypothesis testing
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Comparison of Vs and SPT Soil Liquefaction Assessments of NCEER: Including Hypothesis Testing
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作者 Min-Hao Wu Jui-Pin Wang Chih-Kun Liao 《International Journal of Geosciences》 2023年第11期1085-1099,共15页
Soil liquefaction is one of the complex research topics in geotechnical engineering and engineering geology. Especially after the 1964 Niigata earthquake (Japan) induced many soil liquefaction incidents, a variety of ... Soil liquefaction is one of the complex research topics in geotechnical engineering and engineering geology. Especially after the 1964 Niigata earthquake (Japan) induced many soil liquefaction incidents, a variety of soil liquefaction studies were conducted and reported, including the liquefaction potential assessment methods utilizing the shear wave velocity (V<sub>s</sub>) or SPT-N profiles (SPT: standard penetration test). This study used the V<sub>s</sub> and SPT methods recommended by the National Center for Earthquake Engineering Research (NCEER) to examine which is more conservative according to the assessment results on 41 liquefiable soil layers at sites in two major cities in Taiwan. Statistical hypothesis testing was used to make the analysis more quantitative and objective. Based on three sets of hypothesis tests, it shows that the hypothesis—the SPT method is more conservative than the V<sub>s</sub> method—was not rejected on a 5% level of significance. 展开更多
关键词 Soil Liquefaction Standard Penetration Test Shear Wave Velocity hypothesis testing
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On Testing Equality of K Multiple Correlation Matrices
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作者 A.K.Gupta D.G.Kabe 《Northeastern Mathematical Journal》 CSCD 2000年第4期405-410,共6页
Coutsourides derived an ad hoc nuisance paratmeter removal test for testing equality of two multiple correlation matrices of two independent p variate normal populations under the assumption that a sample of size ... Coutsourides derived an ad hoc nuisance paratmeter removal test for testing equality of two multiple correlation matrices of two independent p variate normal populations under the assumption that a sample of size n is available from each population. This paper presents a likelihood ratio test criterion for testing equality of K multiple correlation matrices and extends the results to the testing of equality of K partial correlation matrices. 展开更多
关键词 normal population multiple correlation matrix partial correlations matrix distribution theory test of hypothesis likelihood ratio test
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Analysis and optimization of the applicability of hypothesis testing methods
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作者 Sirui Zhang 《Advances in Operation Research and Production Management》 2025年第2期75-78,共4页
With the continuous development of science and technology and other fields in today's world,statistical analysis and research have become indispensable research methods in people's daily lives.Among these,hypo... With the continuous development of science and technology and other fields in today's world,statistical analysis and research have become indispensable research methods in people's daily lives.Among these,hypothesis testing plays an important role in fields such as biology,medicine,and economics,and has significant effects in most scenarios.However,the suitability and effectiveness of different hypothesis testing methods vary depending on the context,often leading to different outcomes and levels of accuracy.This paper focuses on discussing various hypothesis testing methods in statistics,such as t-test,chi-square test,z-test,F-test,etc.In addition,this study analyzes various cases in real life and optimize and improve some hypothesis testing methods.Based on a review of existing literature,the study explores how traditional hypothesis testing determines statistical significance—where the null hypothesis is rejected if the test statistic falls within the rejection region.To improve and enhance the determination of the significance level,handle uncertainty,and increase the sample size,this paper proposes alternative methods such as NHST test,Bayesian test,big data sequential test,and failure rate hypothesis test from the perspectives of medicine and kinesiology. 展开更多
关键词 hypothesis testing applicability analysis significance test index evaluation method multiple hypothesis testing
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Statistical condition assessment of existing structures using virtual work error estimator
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作者 蔡晶 吴智深 《Journal of Southeast University(English Edition)》 EI CAS 2007年第4期577-582,共6页
A statistical damage detection and condition assessment scheme for existing structures is developed. First a virtual work error estimator is defined to express the discrepancy between a real structure and its analytic... A statistical damage detection and condition assessment scheme for existing structures is developed. First a virtual work error estimator is defined to express the discrepancy between a real structure and its analytical model, with which a system identification algorithm is derived by using the improved Newton method. In order to investigate its properties in the face of measurement errors, the Monte Carlo method is introduced to simulate the measured data. Based on the identified results, their statistical distributions can be assumed, the status of an existing structure can be statistically evaluated by hypothesis tests. A 5-story, two-bay steel frame is used to carry out numerical simulation studies in detail, and the proposed scheme is proved to be effective. 展开更多
关键词 virtual work constitutive parameter parameter estimation hypothesis test
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Independence Test of Wheat Head Blight Infection
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作者 夏海峰 《Plant Diseases and Pests》 CAS 2010年第5期38-39,53,共3页
The relationship between wheat varieties and occurrence of head blight was discussed, the independence test was carried out by using contingency table.
关键词 hypothesis testing SAMPLE INDEPENDENT
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Testing the mantle plume hypothesis: an IODP effort to drill into the Kamchatka-Okhotsk Sea basement 被引量:8
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作者 Yaoling Niu Xuefa Shi +3 位作者 Tiegang Li Shiguo Wu Weidong Sun Rixiang Zhu 《Science Bulletin》 SCIE EI CAS CSCD 2017年第21期1464-1472,共9页
The great mantle plume debate(GPD) has been going on for ~15 years(Foulger and Natland, 2003;Anderson, 2004; Niu, 2005; Davies, 2005; Foulger, 2005; Campbell, 2005; Campbell and Davies, 2006),centered on whether mantl... The great mantle plume debate(GPD) has been going on for ~15 years(Foulger and Natland, 2003;Anderson, 2004; Niu, 2005; Davies, 2005; Foulger, 2005; Campbell, 2005; Campbell and Davies, 2006),centered on whether mantle plumes exist as a result of Earth's cooling or whether their existence is purely required for convenience in explaining certain Earth phenomena(Niu, 2005). Despite the mounting evidence that many of the so-called plumes may be localized melting anomalies, the debate is likely to continue. We recognize that the slow progress of the debate results from communication difficulties.Many debaters may not truly appreciate(1) what the mantle plume hypothesis actually is, and(2) none of the petrological, geochemical and geophysical methods widely used can actually provide smoking-gun evidence for or against mantle plume hypothesis. In this short paper, we clarify these issues, and elaborate a geologically effective approach to test the hypothesis. According to the mantle plume hypothesis, a thermal mantle plume must originate from the thermal boundary layer at the core-mantle boundary(CMB), and a large mantle plume head is required to carry the material from the deep mantle to the surface. The plume head product in ocean basins is the oceanic plateau, which is a lithospheric terrane that is large(1000's km across), thick(>200 km), shallow(2–4 km high above the surrounding seafloors), buoyant(~1% less dense than the surrounding lithosphere), and thus must be preserved in the surface geology(Niu et al., 2003). The Hawaiian volcanism has been considered as the surface expression of a type mantle plume, but it does not seem to have a(known) plume head product. If this is true, the Hawaiian mantle plume in particular and the mantle plume hypothesis in general must be questioned. Therefore, whether there is an oceanic plateau-like product for the Hawaiian volcanism is key to testing the mantle plume hypothesis, and the Kamchatka-Okhotsk Sea basement is the best candidate to find out if it is indeed the Hawaiian mantle plume head product or not(Niu et al., 2003; Niu, 2004). 展开更多
关键词 Mantle plume debate Geologically testing plume hypothesis Drilling into Kamchatka-Okhotsk Sea BASEMENT
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Robust cubature Kalman filter method for the nonlinear alignment of SINS 被引量:7
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作者 Shi-luo Guo Ying-jie Sun +1 位作者 Li-min Chang Yang Li 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2021年第2期593-598,共6页
Nonlinear initial alignment is a significant research topic for strapdown inertial navigation system(SINS).Cubature Kalman filter(CKF)is a popular tool for nonlinear initial alignment.Standard CKF assumes that the sta... Nonlinear initial alignment is a significant research topic for strapdown inertial navigation system(SINS).Cubature Kalman filter(CKF)is a popular tool for nonlinear initial alignment.Standard CKF assumes that the statics of the observation noise are pre-given before the filtering process.Therefore,any unpredicted outliers in observation noise will decrease the stability of the filter.In view of this problem,improved CKF method with robustness is proposed.Multiple fading factors are introduced to rescale the observation noise covariance.Then the update stage of the filter can be autonomously tuned,and if there are outliers exist in the observations,the update should be less weighted.Under the Gaussian assumption of KF,the Mahalanobis distance of the innovation vector is supposed to be Chi-square distributed.Therefore a judging index based on Chi-square test is designed to detect the noise outliers,determining whether the fading tune are required.The proposed method is applied in the nonlinear alignment of SINS,and vehicle experiment proves the effective of the proposed method. 展开更多
关键词 SINS Nonlinear alignment Cubature Kalman filter ROBUST Multiple fading factors hypothesis test
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Gearbox Deterioration Detection under Steady State,Variable Load, and Variable Speed Conditions 被引量:6
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作者 SHAO Yimin CHRIS K Mechefske +1 位作者 OU Jiafu HU Yumei 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2009年第2期256-264,共9页
Multiple dominant gear meshing frequencies are present in the vibration signals collected from gearboxes and the conventional spiky features that represent initial gear fault conditions are usually difficult to detect... Multiple dominant gear meshing frequencies are present in the vibration signals collected from gearboxes and the conventional spiky features that represent initial gear fault conditions are usually difficult to detect. In order to solve this problem, we propose a new gearbox deterioration detection technique based on autoregressive modeling and hypothesis testing in this paper. A stationary autoregressive model was built by using a normal vibration signal from each shaft. The established autoregressive model was then applied to process fault signals from each shaft of a two-stage gearbox. What this paper investigated is a combined technique which unites a time-varying autoregressive model and a two sample Kolmogorov-Smimov goodness-of-fit test, to detect the deterioration of gearing system with simultaneously variable shaft speed and variable load. The time-varying autoregressive model residuals representing both healthy and faulty gear conditions were compared with the original healthy time-synchronous average signals. Compared with the traditional kurtosis statistic, this technique for gearbox deterioration detection has shown significant advantages in highlighting the presence of incipient gear fault in all different speed shafts involved in the meshing motion under variable conditions. 展开更多
关键词 GEARBOX condition detection hypothesis test time-varying autoregressive(AR) modeling Kolmogorov-Smimov goodness-of-fit test
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Investigation of ionospheric TEC changes related to the 2008 Wenchuan earthquake based on statistic analysis and signal detection 被引量:6
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作者 Jianyong Li Guojie Meng +2 位作者 Min Wang Hua Liao Xuhui Shen 《Earthquake Science》 CSCD 2009年第5期545-553,共9页
Ionospheric TEC (total electron content) time series are derived from GPS measurements at 13 stations around the epicenter of the 2008 Wenchuan earthquake. Defining anomaly bounds for a sliding window by quartile an... Ionospheric TEC (total electron content) time series are derived from GPS measurements at 13 stations around the epicenter of the 2008 Wenchuan earthquake. Defining anomaly bounds for a sliding window by quartile and 2-standard deviation of TEC values, this paper analyzed the characteristics of ionospheric changes before and after the destructive event. The Neyman-Pearson signal detection method is employed to compute the probabilities of TEC abnormalities. Result shows that one week before the Wenchuan earthquake, ionospheric TEC over the epicenter and its vicinities displays obvious abnormal disturbances, most of which are positive anomalies. The largest TEC abnormal changes appeared on May 9, three days prior to the seismic event. Signal detection shows that the largest possibility ofTEC abnormity on May 9 is 50.74%, indicating that ionospheric abnormities three days before the main shock are likely related to the preparation process of the Ms8.0 Wenchuan earthquake. 展开更多
关键词 GPS total electron content (TEC) earthquake precursor abnormal signals hypothesis test
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New deghosting method based on generalized triangulation 被引量:5
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作者 Bai Jing Wang Guohong Xiu Jianjuan Wang Xiaobo 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2009年第3期504-511,共8页
A new deghosting method based on the generalized triangulation is presented. First, two intersection points corresponding to the emitter position are obtained by utilizing two azimuth angles and two elevation angles f... A new deghosting method based on the generalized triangulation is presented. First, two intersection points corresponding to the emitter position are obtained by utilizing two azimuth angles and two elevation angles from two jammed 3-D radars (or 2-D passive sensors). Then, hypothesis testing based deghosting method in the multiple target scenarios is proposed using the two intersection points. In order to analyze the performance of the proposed method, the correct association probability of the true targets and the incorrect association probability of the ghost targets are defined. Finally, the Monte Carlo simulations are given for the proposed method compared with the hinge angle method in the cases of both two and three radars. The simulation results show that the proposed method has better performance than the hinge angle method in three radars case. 展开更多
关键词 deghosting generalized triangulation hinge angle distributed radar network hypothesis testing
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Calorific values and ash contents of different parts of Masson pine trees in southern China 被引量:4
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作者 Wei-sheng ZENG Shou-zheng TANG Qian-hui XIAO 《Journal of Forestry Research》 SCIE CAS CSCD 2014年第4期779-786,共8页
Calorific value of plants is an important parameter for evalu- ating and indexing material cycles and energy conversion in forest eco- systems. Based on mensuration data of 150 sample sets, we analyzed the calorific v... Calorific value of plants is an important parameter for evalu- ating and indexing material cycles and energy conversion in forest eco- systems. Based on mensuration data of 150 sample sets, we analyzed the calorific value (CV) and ash content (AC) of different parts of Masson pine (Pinus massoniana) trees in southern China using hypothesis testing and regression analysis. CV and AC of different tree parts were almost significantly different (P〈0.05). In descending order, ash-free calorific value (AFCV) ranked as foliage 〉 branch 〉 stem bark 〉 root 〉 stem wood, and AC ranked as foliage 〉 stem bark 〉 root 〉 branch 〉 stem wood. CV and AC of stem wood from the top, middle and lower sections of trees differed significantly. CV increased from the top to the lower sections of the tnmk while AC decreased. Mean gross calorific value (GCV) and AFCV of aboveground parts were significantly higher than those of belowground parts (roots). The mean GCV, AFCV and AC of a whole tree of Masson pine were 21.54 kJ/g, 21.74 kJ/g and 0.90%, re- spectively. CV and AC of different tree parts were, to some extent, cor- related with tree diameter, height and origin. 展开更多
关键词 ash-free calorific value ash content gross calorific value hypothesis testing regression analysis Pinus massoniana
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Moderate deviations and hypothesis testing for signal detection problem 被引量:4
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作者 GAO FuQing ZHAO ShouJiang 《Science China Mathematics》 SCIE 2012年第11期2273-2284,共12页
Abstract We use moderate deviations to study the signal detection problem for a diffusion model. We establish a moderate deviation principle for the log-likelihood function of the diffusion model. Then applying the mo... Abstract We use moderate deviations to study the signal detection problem for a diffusion model. We establish a moderate deviation principle for the log-likelihood function of the diffusion model. Then applying the moderate deviation estimates to hypothesis testing for signal detection problem we give a decision region such that its error probability of the second kind tends to zero with faster speed than the error probability of the first kind when the error probability of the first kind is approximated by e-ατ(T), where α〉 0, τ(T) = o(T) and τ(T)→∞ as the observation time T goes to infinity. 展开更多
关键词 large deviations moderate deviations signal detection hypothesis testing
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Model update mechanism for mean-shift tracking 被引量:3
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作者 PengNingsong YangJie LiuErqi 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2005年第1期52-57,共6页
In order to solve the model update problem in mean-shift based tracker, a novel mechanism is proposed. Kalman filter is employed to update object model by filtering object kernel-histogram using previous model and cur... In order to solve the model update problem in mean-shift based tracker, a novel mechanism is proposed. Kalman filter is employed to update object model by filtering object kernel-histogram using previous model and current candidate. A self-tuning method is used for adaptively adjust all the parameters of the filters under the analysis of the filtering residuals. In addition, hypothesis testing servers as the criterion for determining whether to accept filtering result. Therefore, the tracker has the ability to handle occlusion so as to avoid over-update. The experimental results show that our method can not only keep up with the object appearance and scale changes but also be robust to occlusion. 展开更多
关键词 MEAN-SHIFT TRACKING model update Kalman filter hypothesis testing.
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DISPERSION COMPARISONS OF TWO PROBABILITY VECTORS UNDER MULTINOMIAL SAMPLING 被引量:2
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作者 熊世峰 李国英 《Acta Mathematica Scientia》 SCIE CSCD 2010年第3期907-918,共12页
We consider testing hypotheses concerning comparing dispersions between two parameter vectors of multinomial distributions in both one-sample and two-sample cases. The comparison criterion is the concept of Schur majo... We consider testing hypotheses concerning comparing dispersions between two parameter vectors of multinomial distributions in both one-sample and two-sample cases. The comparison criterion is the concept of Schur majorization. A new dispersion index is proposed for testing the hypotheses. The corresponding test for the one-sample problem is an exact test. For the two-sample problem, the bootstrap is used to approximate the null distribution of the test statistic and the p-value. We prove that the bootstrap test is asymptotically correct and consistent. Simulation studies for the bootstrap test are reported and a real life example is presented. 展开更多
关键词 Multinomial distribution DISPERSION DIVERSITY BOOTSTRAP hypothesis testing majorization
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Hypothesis testing for reliability with a three-parameter Weibull distribution using minimum weighted relative entropy norm and bootstrap 被引量:2
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作者 Xin-tao XIA Yin-ping JIN +2 位作者 Yong-zhi XU Yan-tao SHANG Long CHEN 《Journal of Zhejiang University-Science C(Computers and Electronics)》 SCIE EI 2013年第2期143-154,共12页
With the help of relative entropy theory,norm theory,and bootstrap methodology,a new hypothesis testing method is proposed to verify reliability with a three-parameter Weibull distribution.Based on the relative differ... With the help of relative entropy theory,norm theory,and bootstrap methodology,a new hypothesis testing method is proposed to verify reliability with a three-parameter Weibull distribution.Based on the relative difference information of the experimental value vector to the theoretical value vector of reliability,six criteria of the minimum weighted relative entropy norm are established to extract the optimal information vector of the Weibull parameters in the reliability experiment of product lifetime.The rejection region used in the hypothesis testing is deduced via the area of intersection set of the estimated truth-value function and its confidence interval function of the three-parameter Weibull distribution.The case studies of simulation lifetime,helicopter component failure,and ceramic material failure indicate that the proposed method is able to reflect the practical situation of the reliability experiment. 展开更多
关键词 RELIABILITY hypothesis testing Three-parameter Weibull distribution Weighted relative entropy NORM BOOTSTRAP
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