Developmental instability(DI)is a phenomenon whereby organisms are unable to buffer developmental disturbances,resulting in asymmetricvariation of paired traits.Previous research has demonstrated a negative relationsh...Developmental instability(DI)is a phenomenon whereby organisms are unable to buffer developmental disturbances,resulting in asymmetricvariation of paired traits.Previous research has demonstrated a negative relationship between DI,measured as forearm asymmetry,and survivalin the bat Carollia perspicillata.This study aims to test the hypothesis that individuals with higher DI exhibit a lower immune response.We measured a delayed-type hypersensitivity to the antigen phytohemagglutinin(PHA)on 74 males and 65 females of C.perspicillata before and after thebreeding season(BS).Linear models were used to predict the immunological response based on body mass(BM),forearm asymmetry,sex,BS,and testicle length.The best-ftting model accounted for 29% of the variation in immune response and included asymmetry,BM,sex,and BS aspredictors.The immune response was negatively associated with asymmetry and testicle length in males but positively related to asymmetryin females.Both sexes showed a reduced immune response in the late BS.Additionally,the association between immune response and BMchanged direction seasonally,with heavier individuals showing weaker responses early in the BS and stronger responses later.Individual variation in male immunity was predicted by individual attributes,whereas variation in immune response in females was mostly seasonal.Our resultssupport the link between DI,survival,and immune response in short-tailed bats,and suggest that the immunological component measured bythe PHA response may be under fner selection in males due to its stronger correlation with individual traits.展开更多
基金supported by Conselho Nacional de Desenvolvimento Cientifco e Tecnologico(CNPq),Fundacaode Amparoa Pesquisa do Rio de Janeiro(FAPERJ),Fundacaode Amparoa Pesquisa do Estado de Sao Paulo(FAPESPGrant nº2014/16/320-7)Coordenacao de Aperfeicoamentode Pessoal de Nível Superior(CAPES)-Finance Code 001+1 种基金by grants to LGHM and APCN from the Visiting Research Program of the FAPESP(nº2017-17607-6)supported by the PASPA-DGAPA program of the Universidad Nacional Autonoma de Mexico(nº814-2018).
文摘Developmental instability(DI)is a phenomenon whereby organisms are unable to buffer developmental disturbances,resulting in asymmetricvariation of paired traits.Previous research has demonstrated a negative relationship between DI,measured as forearm asymmetry,and survivalin the bat Carollia perspicillata.This study aims to test the hypothesis that individuals with higher DI exhibit a lower immune response.We measured a delayed-type hypersensitivity to the antigen phytohemagglutinin(PHA)on 74 males and 65 females of C.perspicillata before and after thebreeding season(BS).Linear models were used to predict the immunological response based on body mass(BM),forearm asymmetry,sex,BS,and testicle length.The best-ftting model accounted for 29% of the variation in immune response and included asymmetry,BM,sex,and BS aspredictors.The immune response was negatively associated with asymmetry and testicle length in males but positively related to asymmetryin females.Both sexes showed a reduced immune response in the late BS.Additionally,the association between immune response and BMchanged direction seasonally,with heavier individuals showing weaker responses early in the BS and stronger responses later.Individual variation in male immunity was predicted by individual attributes,whereas variation in immune response in females was mostly seasonal.Our resultssupport the link between DI,survival,and immune response in short-tailed bats,and suggest that the immunological component measured bythe PHA response may be under fner selection in males due to its stronger correlation with individual traits.
