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Correction:Cerchar abrasivity test and its applications in rock engineering:A review
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作者 Guangzhe Zhang Kurosch Thuro +2 位作者 Zhengyang Song Wengang Dang Qingsheng Bai 《International Journal of Coal Science & Technology》 2025年第4期280-289,共10页
Correction:International Journal of Coal Science&Technology(2025)12:13 https://doi.org/10.1007/s40789-024-00731-8 In this article(Zhang et al.2025),Tables 6,7,8,10,11 and 13 contain errors as described below.
关键词 rock engineering international journal coal science technology cerchar abrasivity test ERRORS REVIEW
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A self-correction algorithm for positioning error in sequential point bending tests of a microbeam for Young’s modulus based on atomic force microscopy
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作者 Yuxin Liu Linyan Xu 《Nanotechnology and Precision Engineering》 2025年第3期131-137,共7页
The single-point bending method,based on atomic force microscopy(AFM),has been extensively validated for characterizing the structural mechanical properties of micro-and nanobeams.Nevertheless,the influence of AFM pro... The single-point bending method,based on atomic force microscopy(AFM),has been extensively validated for characterizing the structural mechanical properties of micro-and nanobeams.Nevertheless,the influence of AFM probe loading and positioning has yet to be subjected to comprehensive investigation.This paper proposes a novel bending-test method based on sequential loading points,in which a series of evenly distributed loads are applied along the length of the central axis on the upper surface of the cantilever.The preliminary measured values of Young’s modulus for an unknown alloy material were 193,178,and 176 GPa,exhibiting a considerable degree of dispersion.An algorithm for self-correction of the positioning error was developed,and this resulted in a positioning error of 53 nm and a final converged Young’s modulus of 161 GPa. 展开更多
关键词 Microbeam structure Young’s modulus Sequential point bending test Self-correcting positioning error Atomic force microscopy
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Correction to“Prognostic value of preoperative fibrinogen,neutrophil-to-lymphocyte ratio,serum alpha-fetoprotein,and prealbumin for patients with primary liver cancer undergoing transarterial chemoembolization”
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作者 Qi-Qi Liu Ya-Dong Li +4 位作者 Jia-Xin Chen Lin-Lin Zhang Rong-Chun Guan Wei Zhao Ling-Yu Meng 《World Journal of Gastrointestinal Oncology》 2026年第1期300-301,共2页
Correction to“Liu QQ,Li YD,Chen JX,Zhang LL,Guan RC,Zhao W,Meng LY.Prognostic value of preoperative fibrinogen,neutrophil-to-lymphocyte ratio,serum alpha-fetoprotein,and prealbumin for patients with primary liver can... Correction to“Liu QQ,Li YD,Chen JX,Zhang LL,Guan RC,Zhao W,Meng LY.Prognostic value of preoperative fibrinogen,neutrophil-to-lymphocyte ratio,serum alpha-fetoprotein,and prealbumin for patients with primary liver cancer undergoing transarterial chemoembolization.World J Gastrointest Oncol 2025;17(6):103198 PMID:40547171 DOI:10.4251/wjgo.v17.i6.103198”.The funding number listed in the"Supported by"section of this article needs to be corrected. 展开更多
关键词 World Journal of Gastrointestinal Oncology correction
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Key role of Levitt’s carbon monoxide breath test in revealing coexistent Gilbert syndrome and erythropoietic protoporphyria:A case report
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作者 Ling-Ling Kang Hou-De Zhang 《World Journal of Clinical Cases》 2026年第1期28-33,共6页
It is challenging to diagnose isolated hyperbilirubinemia with rare and complex etiologies under the constraints of traditional testing conditions.Herein,we present a rare case of coexisting Gilbert syndrome(GS)and er... It is challenging to diagnose isolated hyperbilirubinemia with rare and complex etiologies under the constraints of traditional testing conditions.Herein,we present a rare case of coexisting Gilbert syndrome(GS)and erythropoietic protoporphyria(EPP),which has not been previously documented.CASE SUMMARY We present a rare case of coexisting GS and EPP in a 23-year-old Chinese male with a long history of jaundice and recently found splenomegaly.Serial nonspecific hemolysis screening tests yielded inconsistent results,and investigations for common hemolytic etiologies were negative.However,Levitt’s carbon monoxide breath test,which measures erythrocyte lifespan(the gold-standard marker of hemolysis),demonstrated significant hemolysis,revealing a markedly shortened erythrocyte lifespan of 11 days(normal average 120 days).Genetic testing subsequently confirmed EPP with a homozygous ferrochelatase gene mutation and GS with a heterozygous uridine diphosphate glucuronosyl trans-ferase 1A1 gene mutation.CONCLUSION The rapid,non-invasive Levitt’s carbon monoxide breath test resolved the diagnostic challenge posed by a rare and complex cause of hyperbilirubinemia. 展开更多
关键词 Isolated hyperbilirubinemia Erythropoietic protoporphyria Gilbert syndrome HEMOLYSIS Levitt’s carbon monoxide breath test Erythrocyte lifespan Case report
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Phase aberration correction in ultrasonic phased array non-destructive testing systems
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作者 赵霞 王召巴 刘宾 《Journal of Measurement Science and Instrumentation》 CAS CSCD 2015年第1期47-52,共6页
Phase aberration correction for medical ultrasound systems has attracted a great deal of attention. Since phased array techniques are now widely employed for industrial non-destructive testing (NDT) applications in ... Phase aberration correction for medical ultrasound systems has attracted a great deal of attention. Since phased array techniques are now widely employed for industrial non-destructive testing (NDT) applications in various fields, the problem of phase aberrations in the process of NDT testing is considered. The technique of cross-covariance for phase aberration correction is presented. The performance of the technique for phase aberration correction is tested by means of echo signals obtained in practical non-destructive testing experiment. The results show that the technique has the better accuracy of phase correction. 展开更多
关键词 ultrasonic phased array non-destructive testing phase aberration correction cross-covariance method
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Effects of tube system and data correction for fluctuating pressure test in wind tunnel 被引量:8
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作者 Xue WANG Xunnian WANG +2 位作者 Xiaobo REN Xiwei YIN Weihua WANG 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2018年第4期710-718,共9页
The accuracy of fluctuating pressure test in wind tunnel is affected by the tube system. By employing contradistinctive experimental method, systematic study was conducted to investigate the effects of the tube system... The accuracy of fluctuating pressure test in wind tunnel is affected by the tube system. By employing contradistinctive experimental method, systematic study was conducted to investigate the effects of the tube system on fluctuating pressure. The analyzed tube system parameters include tube length, inside diameter, curvature, deflection angle, thickness, material, restrictor length,restrictor inside diameter, and restrictor place. It is found that all the tube system parameters mentioned above except tube curvature have non-negligible effects on fluctuating pressure. Based on the research results, test methods were presented for the fluctuating pressure measurement in low-speed wind tunnel, which can obviously improve the data accuracy but not lose test efficiency. The effectiveness of the method is verified by the wind tunnel test. 展开更多
关键词 Data correction Fluctuating pressure Frequency response function Tube system Wind tunnel test
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Use of Plastic Correction Formula to Improve Accuracy of Welding Residual Stress Test with Blind-Hole Method 被引量:4
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作者 Qiu Zhao Kongsheng Chen +3 位作者 Meizhong Chen Bruno Briseghella Zhiyong Guo Guotao Yang 《Transactions of Tianjin University》 EI CAS 2018年第5期480-488,共9页
The blind-hole method is the most widely used approach to experimentally determine the distribution of residual stress. This paper aims to improve test accuracy of welding residual stress and conducts an experimental ... The blind-hole method is the most widely used approach to experimentally determine the distribution of residual stress. This paper aims to improve test accuracy of welding residual stress and conducts an experimental study on the strain release factors involved when using the blind-hole method for Q235 and Q345, two steels commonly used in building structures. The ranges of strain release factors A and B in the elastic stage, the effects of strain release factors on residual stress calculated values, and the plastic corrected strain release factors are analyzed considering of the effect of plastic deformation around the blind hole on measurement accuracy. Finally, a simplified calculation formula to determine strain release factors is proposed for use with the blind-hole method. Results show that in the elastic stage, strain release factor A for Q235 and Q345 ranges from-0.399 to-0.525 and strain release factor B from-0.791 to-0.960. Changing the strain release factors A and B shows that calculated residual tensile stress varies in relation to a decrease in both factor values. However, there is a increase in calculated residual compressive stress with a decrease in the strain release factor A value, but there is an decrease with a decrease in strain release factor B value. Calculated residual stress applied to elastic strain release factors is compared with that applied to amended plastic strain release factors for Q235 steel. The maximum deviation between calculated residual stress and test stress is reduced from 21.1 to 1.0%,and for Q345 steel from 26.5 to 1.2%. It is thus evident that the plastic correction formula proposed in this paper can be used in calculations when conducting a residual stress test. 展开更多
关键词 Blind-hole method WELDING RESIDUAL stress·Calibration test STRAIN release FACTOR PLASTIC correction
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Research on aiming methods for small sample size shooting tests of two-dimensional trajectory correction fuse 被引量:1
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作者 Chen Liang Qiang Shen +4 位作者 Zilong Deng Hongyun Li Wenyang Pu Lingyun Tian Ziyang Lin 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第3期506-517,共12页
The longitudinal dispersion of the projectile in shooting tests of two-dimensional trajectory corrections fused with fixed canards is extremely large that it sometimes exceeds the correction ability of the correction ... The longitudinal dispersion of the projectile in shooting tests of two-dimensional trajectory corrections fused with fixed canards is extremely large that it sometimes exceeds the correction ability of the correction fuse actuator.The impact point easily deviates from the target,and thus the correction result cannot be readily evaluated.However,the cost of shooting tests is considerably high to conduct many tests for data collection.To address this issue,this study proposes an aiming method for shooting tests based on small sample size.The proposed method uses the Bootstrap method to expand the test data;repeatedly iterates and corrects the position of the simulated theoretical impact points through an improved compatibility test method;and dynamically adjusts the weight of the prior distribution of simulation results based on Kullback-Leibler divergence,which to some extent avoids the real data being"submerged"by the simulation data and achieves the fusion Bayesian estimation of the dispersion center.The experimental results show that when the simulation accuracy is sufficiently high,the proposed method yields a smaller mean-square deviation in estimating the dispersion center and higher shooting accuracy than those of the three comparison methods,which is more conducive to reflecting the effect of the control algorithm and facilitating test personnel to iterate their proposed structures and algorithms.;in addition,this study provides a knowledge base for further comprehensive studies in the future. 展开更多
关键词 Two-dimensional trajectory correction fuse Small sample size test Compatibility test KL divergence Fusion bayesian estimation
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Correction to “Effect of probiotic Lactobacillus plantarum Dad-13 powder consumption on the gut microbiota and intestinal health of overweight adults”. World J Gastroenterol 2021;27(1): 107-128 [PMID: 33505154 DOI: 10.3748/wjg.v27.i1.107] 被引量:2
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作者 Endang Sutriswati Rahayu 《World Journal of Gastroenterology》 SCIE CAS 2021年第38期6511-6512,共2页
We corrected the wrong name of the primers used in this study.The correct name should be Bakt_341F(5′-CGCTCTTCCGATCTCTGCCTACGGGNGGCWGCAG-3′)and Bakt_805R(5′-TGCTCTTCCGATCTGACGACTACHVGGGTATCTAATCC-3′).
关键词 correction PRIMERS Wrong name Error Suggestions
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Correction to: Recent developments in photoacoustic imaging and sensing for nondestructive testing and evaluation 被引量:2
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作者 Sung-Liang Chen Chao Tian 《Visual Computing for Industry,Biomedicine,and Art》 EI 2021年第1期90-90,共1页
Following publication of the original article[1],the authors identified an error in the article title.The first word ‘Review’ is added mistakenly by the typesetter.
关键词 testing MISTAKE evaluation
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The effect of confining boundary on soil deformation in one dimensional frost heave tests and the theoretical volume correction 被引量:1
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作者 XueWen Zhao Xu Li +1 位作者 JianKun Liu Yu Zhang 《Research in Cold and Arid Regions》 CSCD 2013年第5期587-590,共4页
Frost heave is one of the major complications in highway construction in cold regions. Laboratory experiments are im- portant in the study frost heave behavior of soils, and one-dimensional frost heave experiments are... Frost heave is one of the major complications in highway construction in cold regions. Laboratory experiments are im- portant in the study frost heave behavior of soils, and one-dimensional frost heave experiments are the easiest way to evaluate the soil frost heave potential. In a one dimensional frost heave test, the deformation in axial direction is non-uniform because of the confining effect of the cutting ring's sidewall. If the effect of confining boundary on soil de- formation is ignored, the deformation will be over-estimated. In this paper, the effect of confining boundary on soil de- formation is theoretically studied and a volume correction method is developed and applied to the frost heave test of a sulfite saline soil. Test results demonstrate that the sulfite saline soil will expand to a loose, low-density state after several freezing-thawing cycles under the condition of zero axial stress. 展开更多
关键词 freezing-thawing cycle critical void ratio one-dimensional frost heave test
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基于波形比对TestBench的Verilog在线自动测试系统设计 被引量:1
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作者 黄继业 金清嵩 +1 位作者 李平 刘鑫 《实验室研究与探索》 北大核心 2025年第2期91-94,109,共5页
为解决Verilog编程练习需求大和现有在线测评系统无法较好地支持Verilog在线评测的问题,设计了基于波形比对TestBench的Verilog在线自动测试系统。系统将标准答案源码和学生提交代码分别仿真,得到两种输出波形并转换为txt文本加以比对,... 为解决Verilog编程练习需求大和现有在线测评系统无法较好地支持Verilog在线评测的问题,设计了基于波形比对TestBench的Verilog在线自动测试系统。系统将标准答案源码和学生提交代码分别仿真,得到两种输出波形并转换为txt文本加以比对,根据比对结果在线自动评分。根据代码正确率给出具体分数,并将代码错误信息以文本形式反馈给学生,帮助学生全面评估自身水平并快速定位纠错。该系统已部署至程序设计类实验辅助教学平台,经过教学实践,能有效提升学生的Verilog编程能力,在教学中取得了显著成效。 展开更多
关键词 Verilog在线自动测试 OJ系统 测试基准 波形比对
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Test and Correction of CUACE Model in Air Quality Forecast in the Qinghai-Tibet Plateau:A Case Study of Xining City
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作者 Xiaoning GUO Changrong TAN +1 位作者 Haixiao ZHANG Yu WANG 《Meteorological and Environmental Research》 CAS 2022年第1期53-58,共6页
Based on the data of national monitoring points of air pollution control in Xining from 2015 to 2017,the air quality prediction of CUACE model in Xining was tested by using the method of national environmental meteoro... Based on the data of national monitoring points of air pollution control in Xining from 2015 to 2017,the air quality prediction of CUACE model in Xining was tested by using the method of national environmental meteorological numerical model prediction quality inspection and evaluation.The results show that the prediction accuracy of the CAUCE model for the primary pollutants in Xining region during 2015-2017 was generally higher in the winter half year,and the maximum appeared in November 2016.The prediction accuracy in 24,48 and 72 h was more than 70%.The prediction accuracy of the model in the summer half year was low.The primary pollutants in Xining area were PM_(10),PM_(2.5),O_(3),NO_(2)and CO.The prediction accuracy of PM_(10)was the highest,followed by PM_(2.5),while that of O 3 was the lowest.TS score of 24-hour forecast of light pollution was greater than 0 in the winter half year,and it was the highest in December when the unreported rate was also the highest;the empty report rate existed all year round,and was the highest from May to June.Forecast deviation was greater than 0 in the winter half year,and the maximum appeared in January.The 48-hour and 72-hour model forecast were consistent with the 24-hour forecast.The forecast effect of the model on sudden pollution weather was poor,and moderate pollution,severe pollution,and serious pollution weather occurred less frequently in Xining region,so there was fewer model forecast of this kind of pollution.Besides,among the 24-,48-and 72-hour forecast values of the model,there were many empty reports of this kind of pollution,and the empty report rate was high. 展开更多
关键词 CUACE model AQI index Xining test and correction
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基于ETest的嵌入式软件测试应用与实践
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作者 赵聚雪 郑楚锋 《工业控制计算机》 2025年第9期48-50,共3页
随着技术的发展,嵌入式产品越来越丰富,为了保障嵌入式软件的质量,对嵌入式软件测试的研究也越来越多,探索了国产半实物仿真测试平台ETest开展嵌入式软件测试的应用过程,并对嵌入式软件测试与Web应用软件测试的异同进行了简要分析。
关键词 Etest 嵌入式软件 软件测试 WEB
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Correction to:Production and test of sPHENIX W/SciFiber electromagnetic calorimeter blocks in China
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作者 Xiao-Zhou Yu Xi-Yang Wang +11 位作者 Wei-Hu Ma Shi-Hong Fu Peng-Fei Sun Jin-Xing Song Wan-Bing He Yang Shen Long Ma Jin-Hui Chen Huan-Zhong Huang Si-Guang Wang Jing Zhou Xiao-Mei Li 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第11期138-138,共1页
Correction to:Nuclear Science and Techniques(2024)35:145 https://doi.org/10.1007/s41365-024-01517-y In this article the author’s name Wan-Bing He was incorrectly written as Wan-Bin He.The original article has been co... Correction to:Nuclear Science and Techniques(2024)35:145 https://doi.org/10.1007/s41365-024-01517-y In this article the author’s name Wan-Bing He was incorrectly written as Wan-Bin He.The original article has been corrected. 展开更多
关键词 BLOCKS corrected CALORIMETER
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Correction to“Performance of a serological IgM and IgG qualitative test for COVID-19 diagnosis:An experimental study in Brazil”
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作者 Fabrício Freire de Melo Lilian Martins Oliveira Diniz +9 位作者 JoséNélio Januário João Fernando Gonçalves Ferreira Rafael Santos Dantas Miranda Dórea Breno Bittencourt de Brito Hanna Santos Marques Fabian Fellipe Bueno Lemos Marcel Silva Luz Samuel Luca Rocha Pinheiro Gifone Aguiar Rocha Dulciene Maria de Magalhães Queiroz 《World Journal of Experimental Medicine》 2023年第3期47-49,共3页
Correction to“Freire de Melo F,Martins Oliveira Diniz L,Nélio Januário J,Fernando Gonçalves Ferreira J,Dórea RSDM,de Brito BB,Marques HS,Lemos FFB,Silva Luz M,Rocha Pinheiro SL,de Magalhães Q... Correction to“Freire de Melo F,Martins Oliveira Diniz L,Nélio Januário J,Fernando Gonçalves Ferreira J,Dórea RSDM,de Brito BB,Marques HS,Lemos FFB,Silva Luz M,Rocha Pinheiro SL,de Magalhães Queiroz DM.Performance of a serological IgM and IgG qualitative test for COVID-19 diagnosis:An experimental study in Brazil.World J Exp Med 2022;12(5):100-103[PMID:36196438 DOI:10.5493/wjem.v12.i5.100]”.In this article,we identified an issue with the“Acknowledgments”section.Here,we then provide a recognition section for our supporting institutions. 展开更多
关键词 correction COVID-19 serological testing Serologic tests Rapid diagnostic
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Research of NOx Sensors Performance Test 被引量:1
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作者 Zhengang Zhang Zhonggang Tang +3 位作者 Wei Gao Li Liu Cong Wang Hourui Sun 《Journal of Materials Science and Chemical Engineering》 2025年第2期23-30,共8页
NOx sensors, as a core component of diesel engine exhaust treatment system, play an important role in exhaust emission control, which can accurately and quickly detect the NOx and O2 concentration. It has become a nec... NOx sensors, as a core component of diesel engine exhaust treatment system, play an important role in exhaust emission control, which can accurately and quickly detect the NOx and O2 concentration. It has become a necessary option for the detection of existing exhaust emission standards. At present, there is limited and scattered information on knowledge and test methods of NOx sensors, the research of NOx sensors has become a challenging research topic at home and abroad. Based on these requirements, the article systematically integrates the knowledge of principle and testing methods. First of all, through introducing functional description of NOx sensors and the basic principle of NOx sensors, the relevant scholars can have an overall understanding of the product and master the operation mode of products. Secondly, the current status of performance test bench and methods of NOx sensors were described, which can contribute to having a clear understanding of the development process. After that, a new structure of NOx sensors test bench was purposed, which contains six major units including standard gas source, gas mixing unit, analyzer measurement unit, sensor measurement unit, data processing and display unit, exhaust gas treatment unit. And the test bench was validated. The experimental results show that the test bench has the advantages of high-repeatability, high reliability and low cost. And it can realize automatic detection of multiple target values, which is worthy further promotion. Thereby, the article can contribute to the development of its technology indirectly. 展开更多
关键词 NOx Sensors FUNCTION Performance test Basic Principle
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Improving the Seasonal Forecast of Summer Precipitation in Southeastern China Using a CycleGAN-based Deep Learning Bias Correction Method 被引量:1
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作者 Song YANG Fenghua LING +1 位作者 Jing-Jia LUO Lei BAI 《Advances in Atmospheric Sciences》 2025年第1期26-35,共10页
Accurate seasonal precipitation forecasts,especially for extreme events,are crucial to preventing meteorological hazards and their potential impacts on national development,social activity,and security.However,the int... Accurate seasonal precipitation forecasts,especially for extreme events,are crucial to preventing meteorological hazards and their potential impacts on national development,social activity,and security.However,the intensity of summer precipitation is often largely underestimated in many current dynamic models.This study uses a deep learning method called Cycle-Consistent Generative Adversarial Networks(CycleGAN)to improve the seasonal forecasts for June-JulyAugust precipitation in southeastern China by the Nanjing University of Information Science and Technology Climate Forecast System(NUIST-CFS 1.0).The results suggest that the CycleGAN-based model significantly improves the accuracy in predicting the spatiotemporal distribution of summer precipitation compared to the traditional quantile mapping(QM)method.Using the unpaired bias-correction model,we can also obtain advanced forecasts of the frequency,intensity,and duration of extreme precipitation events over the dynamic model predictions.This study expands the potential applications of deep learning models toward improving seasonal precipitation forecasts. 展开更多
关键词 bias correction CycleGAN QM NUIST-CFS 1.0 extreme precipitation
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Multi-Scale Dilated Convolution Network for SPECT-MPI Cardiovascular Disease Classification with Adaptive Denoising and Attenuation Correction
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作者 A.Robert Singh Suganya Athisayamani +1 位作者 Gyanendra Prasad Joshi Bhanu Shrestha 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期299-327,共29页
Myocardial perfusion imaging(MPI),which uses single-photon emission computed tomography(SPECT),is a well-known estimating tool for medical diagnosis,employing the classification of images to show situations in coronar... Myocardial perfusion imaging(MPI),which uses single-photon emission computed tomography(SPECT),is a well-known estimating tool for medical diagnosis,employing the classification of images to show situations in coronary artery disease(CAD).The automatic classification of SPECT images for different techniques has achieved near-optimal accuracy when using convolutional neural networks(CNNs).This paper uses a SPECT classification framework with three steps:1)Image denoising,2)Attenuation correction,and 3)Image classification.Image denoising is done by a U-Net architecture that ensures effective image denoising.Attenuation correction is implemented by a convolution neural network model that can remove the attenuation that affects the feature extraction process of classification.Finally,a novel multi-scale diluted convolution(MSDC)network is proposed.It merges the features extracted in different scales and makes the model learn the features more efficiently.Three scales of filters with size 3×3 are used to extract features.All three steps are compared with state-of-the-art methods.The proposed denoising architecture ensures a high-quality image with the highest peak signal-to-noise ratio(PSNR)value of 39.7.The proposed classification method is compared with the five different CNN models,and the proposed method ensures better classification with an accuracy of 96%,precision of 87%,sensitivity of 87%,specificity of 89%,and F1-score of 87%.To demonstrate the importance of preprocessing,the classification model was analyzed without denoising and attenuation correction. 展开更多
关键词 SPECT-MPI CAD MSDC DENOISING attenuation correction classification
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Advances and challenges in gastric cancer testing:the role of biomarkers 被引量:1
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作者 Yu Sun Pavitratha Puspanathan +1 位作者 Tony Lim Dongmei Lin 《Cancer Biology & Medicine》 2025年第3期212-230,共19页
Advances in the identification of molecular biomarkers and the development of targeted therapies have enhanced the prognosis of patients with advanced gastric cancer.Several established biomarkers have been widely int... Advances in the identification of molecular biomarkers and the development of targeted therapies have enhanced the prognosis of patients with advanced gastric cancer.Several established biomarkers have been widely integrated into routine clinical diagnostics of gastric cancer to guide personalized treatment.Human epidermal growth factor receptor 2(HER2)was the first molecular biomarker to be used in gastric cancer with trastuzumab being the first approved targeted therapy for HER2-positive gastric cancer.Programmed death-ligand 1 positivity and microsatellite instability can guide the use of immunotherapies,such as pembrolizumab and nivolumab.More recently,zolbetuximab has been approved for patients with claudin 18.2-positive diseases in some countries.More targeted therapies,including savolitinib for MET-positive patients,are currently under clinical investigation.However,the clinical application of these diagnostic approaches could be hampered by many existing challenges,including invasive and costly sampling methods,variability in immunohistochemistry interpretation,high costs and long turnaround times for next-generation sequencing,the absence of standardized and clinically validated diagnostic cut-off values for some biomarkers,and tumor heterogeneity.Novel testing and analysis techniques,such as artificial intelligence-assisted image analysis and multiplex immunohistochemistry,and emerging therapeutic strategies,including combination therapies that integrate immune checkpoint inhibitors with targeted therapies,offer potential solutions to some of these challenges.This article reviews recent progress in gastric cancer testing,outlines current challenges,and explores future directions for biomarker testing and targeted therapy for gastric cancer. 展开更多
关键词 Gastric cancer testING DIAGNOSIS biomarkers precision therapy
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