By the end of 2021, China's high-speed railway had operated more than 40,000 kilometers, and the transportation network of four vertical and four horizontal high-speed railway lines had basically taken shape. In o...By the end of 2021, China's high-speed railway had operated more than 40,000 kilometers, and the transportation network of four vertical and four horizontal high-speed railway lines had basically taken shape. In order to meet the needs of China's high-speed railway construction, China Railway Corporation launched a major scientific research project "Research on Key Technologies for the Construction of Long-span Simply Supported Beams for High-speed Railways" in 2016. Beijing Railway Fangshan Bridge Co., Ltd. is mainly responsible for the manufacture of 40-meter full-scale test beams, and template assembly is an important factor affecting the quality of the test beams. The summary of formwork assembling construction technology for 40-meter full-scale test beam can provide technical guarantee for formwork assembling construction for the production of high-speed railway long-span simply supported beam in the future.展开更多
Six trigonal prismatic metallocages(TPMs)composed of 24 components,namely{(Cu_(3)L_(3))(Cu_(2)X_(2))_(3)(Cu_(3)L_(3))}·xG(HL=4-(quinoline-8-thio)-3,5-dimethyl-1H-pyrazole,G=benzene(B),methylbenzene(MB),1,3,5-trip...Six trigonal prismatic metallocages(TPMs)composed of 24 components,namely{(Cu_(3)L_(3))(Cu_(2)X_(2))_(3)(Cu_(3)L_(3))}·xG(HL=4-(quinoline-8-thio)-3,5-dimethyl-1H-pyrazole,G=benzene(B),methylbenzene(MB),1,3,5-triphenylbenzene(TPB),x=3 for B,MB and 1 for TPB),are reported.They were constructed by three rhombicCu_(2)X_(2)units as columns connecting two planar syn-Cu_(3)L_(3)faces,templated by G molecules.The structural analysis and EDA calculations reveal that C-H…πdominate their host-vip interactions.展开更多
CONSPECTUS:The concept of micrometer-scale swimming robots,also known as microswimmers,navigating the human body to perform robotic tasks has captured the public imagination and inspired researchers through its numero...CONSPECTUS:The concept of micrometer-scale swimming robots,also known as microswimmers,navigating the human body to perform robotic tasks has captured the public imagination and inspired researchers through its numerous representations in popular media.This attention highlights the enormous interest in and potential of this technology for biomedical applications,such as cargo delivery,diagnostics,and minimally invasive surgery,as well as for applications in microfluidics and manufacturing.To achieve the collective behavior and control required for microswimmers to effectively perform such actions within complex,in vivo and microfluidic environments,they must meet a strict set of engineering criteria.These requirements include,but are not limited to,small size,structural monodispersity,flexibility,biocompatibility,and multifunctionality.Additionally,microswimmers must be able to adapt to delicate environments,such as human vasculature,while safely performing preprogrammed tasks in response to chemical and mechanical signals.Naturally information-bearing biopolymers,such as peptides,RNA,and DNA,can provide programmability,multifunctionality,and nanometer-scale precision for manufactured structures.In particular,DNA is a useful engineering material because of its predictable and well-characterized material properties,as well as its biocompatibility.Moreover,recent advances in DNA nanotechnology have enabled unprecedented abilities to engineer DNA nanostructures with tunable mechanics and responsiveness at nano-and micrometer scales.Incorporating DNA nanostructures as subcomponents in microswimmer systems can grant these structures enhanced deformability,reconfigurability,and responsiveness to biochemical signals while maintaining their biocompatibility,providing a versatile pathway for building programmable,multifunctional microand nanoscale machines with robotic capabilities.In this Account,we highlight our recent progress toward the experimental realization of responsive microswimmers made with compliant DNA components.We present a hybrid top-down,bottom-up fabrication method that combines templated assembly with structural DNA nanotechnology to address the manufacturing limitations of flexibly linked microswimmers.Using this method,we construct microswimmers with enhanced structural complexity and more controlled particle placement,spacing,and size,while maintaining the compliance of their DNA linkage.We also present a novel experimental platform that utilizes two-photon polymerization(TPP)to fabricate millimeter-scale swimmers(milliswimmers)with fully customizable shapes and integrated flexible linkers.This platform addresses limitations related to population-level heterogeneity in micrometer-scale systems,allowing us to isolate the effects of milliswimmer designs from variations in their physical dimensions.Using this platform,we interrogate established hydrodynamic models of microswimmer locomotion and explore how design and actuation parameters influence milliswimmer velocity.We next explore opportunities for enhancing microswimmer responsiveness,functionality,and physical intelligence through the inclusion of nucleic acid subcomponents.Finally,we highlight how our parallel research on xeno nucleic acids and interfacing DNA nanotechnology with living cells can enable the creation of fully organic,truly biocompatible microswimmers with enhanced functionality,improving the viability of microswimmers for applications in healthcare,manufacturing,and synthetic biology.展开更多
Three-dimensional(3D)graphene networks are performance boosters for functional nanostructures in energy-related fields.Although tremendous intriguing nanostructures-decorated 3D graphene networks have been realized,on...Three-dimensional(3D)graphene networks are performance boosters for functional nanostructures in energy-related fields.Although tremendous intriguing nanostructures-decorated 3D graphene networks have been realized,on-demand decoration of nanostructures in the specified position of interest within the whole 3D graphene skeleton is still out of reach,shedding limitations on constructing more sophisticated components with programmable structures which offer enormous potential for the enhancement of performance and exploration of new functions.Here,we report the melamine-sponge(MS)-templated hydrothermal method capable of realizing reduced graphene oxide(RGO)-nanostructure composite aerogels with programmable structures and compositions.The key of this method is using the MS template to preset the structures of choice through programmable solution-processed immobilization of graphene oxide(GO)and nanostructures.Remarkably,the hydrothermal treatment simultaneously removed the MS template and reduced the GO networks without changing the preset structures.We showcased nine typical RGO-nanostructures composite aerogels to demonstrate the versatility of the MS-templated hydrothermal method.展开更多
Conductive and adhesive hydrogels are promising materials for designing bioelectronics.To satisfy the high conductivity of bioelectronic devices,metal nanomaterials have been used to fabricate composite hydrogels.Howe...Conductive and adhesive hydrogels are promising materials for designing bioelectronics.To satisfy the high conductivity of bioelectronic devices,metal nanomaterials have been used to fabricate composite hydrogels.However,the fabrication of a conductive-nanomaterial-incorporated hydrogel with high performance is a great challenge because of the easy aggregation nature of conductive nanomaterials making processing difficult.Here,we report a kind of adhesive aero-hydrogel hybrid conductor(AAHC)with stretchable,adhesive and anti-bacteria properties by in situ formation of a hydrogel network in the aerogel-silver nanowires(AgNWs)assembly.The AgNWs with good conductivity are wellintegrated on the inner-surface of shape-memory chitosan aerogel,which created a conductive framework to allow hydrogel back-filling.Reinforcement by the aerogel-silver makes the hybrid hydrogel tough and stretchable.Functional groups from the hydrogel allow strong adhesion to wet tissues through molecular stitches.The inherent bacteria-killing ability of silver ions endows the conductive hydrogel with excellent anti-bacteria performance.The proposed facile strategy of aerogel-assisted assembly of metal nanomaterials with hydrogel opens a new route to incorporate functional nanoscale building blocks into hydrogels.展开更多
The organic lyotropic liquid crystal with long-range structural order is used as template to assemble inorganic/organic hybrid by doping pre-fabricated Ag nanoparticles. The lamellar hybrid with both hydrophilic and h...The organic lyotropic liquid crystal with long-range structural order is used as template to assemble inorganic/organic hybrid by doping pre-fabricated Ag nanoparticles. The lamellar hybrid with both hydrophilic and hydrophobic particles doped simultaneously is realized for the first time. The change of template structure after doping and the stability origin of dual-doped system are characterized by small angle X-ray scattering and polarized optical microscopy. Results show that the interaction and space matching between surfactant bilayers and doped particles are key factors to obtain stable hybrid.展开更多
文摘By the end of 2021, China's high-speed railway had operated more than 40,000 kilometers, and the transportation network of four vertical and four horizontal high-speed railway lines had basically taken shape. In order to meet the needs of China's high-speed railway construction, China Railway Corporation launched a major scientific research project "Research on Key Technologies for the Construction of Long-span Simply Supported Beams for High-speed Railways" in 2016. Beijing Railway Fangshan Bridge Co., Ltd. is mainly responsible for the manufacture of 40-meter full-scale test beams, and template assembly is an important factor affecting the quality of the test beams. The summary of formwork assembling construction technology for 40-meter full-scale test beam can provide technical guarantee for formwork assembling construction for the production of high-speed railway long-span simply supported beam in the future.
基金supported by the National Natural Science Foundation of China(No.21731002,21975104,22071141,21471094)the Guangdong Major Project of Basic and Applied Research(No.2019B030302009)+1 种基金the Guangdong Basic and Applied Basic Research Foundation(No.2019A1515012162)the Open Fund of Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications(No.2020A05)。
文摘Six trigonal prismatic metallocages(TPMs)composed of 24 components,namely{(Cu_(3)L_(3))(Cu_(2)X_(2))_(3)(Cu_(3)L_(3))}·xG(HL=4-(quinoline-8-thio)-3,5-dimethyl-1H-pyrazole,G=benzene(B),methylbenzene(MB),1,3,5-triphenylbenzene(TPB),x=3 for B,MB and 1 for TPB),are reported.They were constructed by three rhombicCu_(2)X_(2)units as columns connecting two planar syn-Cu_(3)L_(3)faces,templated by G molecules.The structural analysis and EDA calculations reveal that C-H…πdominate their host-vip interactions.
基金supported in part by the National Science Foundation(NSF)grants 1739308(R.E.T.)2132886(R.E.T.),NSF GREP DGE1745016/DGE2140739(T.I.)a seed grant from the Carnegie Mellon University Manufacturing Futures Institute(R.E.T.and S.B.).
文摘CONSPECTUS:The concept of micrometer-scale swimming robots,also known as microswimmers,navigating the human body to perform robotic tasks has captured the public imagination and inspired researchers through its numerous representations in popular media.This attention highlights the enormous interest in and potential of this technology for biomedical applications,such as cargo delivery,diagnostics,and minimally invasive surgery,as well as for applications in microfluidics and manufacturing.To achieve the collective behavior and control required for microswimmers to effectively perform such actions within complex,in vivo and microfluidic environments,they must meet a strict set of engineering criteria.These requirements include,but are not limited to,small size,structural monodispersity,flexibility,biocompatibility,and multifunctionality.Additionally,microswimmers must be able to adapt to delicate environments,such as human vasculature,while safely performing preprogrammed tasks in response to chemical and mechanical signals.Naturally information-bearing biopolymers,such as peptides,RNA,and DNA,can provide programmability,multifunctionality,and nanometer-scale precision for manufactured structures.In particular,DNA is a useful engineering material because of its predictable and well-characterized material properties,as well as its biocompatibility.Moreover,recent advances in DNA nanotechnology have enabled unprecedented abilities to engineer DNA nanostructures with tunable mechanics and responsiveness at nano-and micrometer scales.Incorporating DNA nanostructures as subcomponents in microswimmer systems can grant these structures enhanced deformability,reconfigurability,and responsiveness to biochemical signals while maintaining their biocompatibility,providing a versatile pathway for building programmable,multifunctional microand nanoscale machines with robotic capabilities.In this Account,we highlight our recent progress toward the experimental realization of responsive microswimmers made with compliant DNA components.We present a hybrid top-down,bottom-up fabrication method that combines templated assembly with structural DNA nanotechnology to address the manufacturing limitations of flexibly linked microswimmers.Using this method,we construct microswimmers with enhanced structural complexity and more controlled particle placement,spacing,and size,while maintaining the compliance of their DNA linkage.We also present a novel experimental platform that utilizes two-photon polymerization(TPP)to fabricate millimeter-scale swimmers(milliswimmers)with fully customizable shapes and integrated flexible linkers.This platform addresses limitations related to population-level heterogeneity in micrometer-scale systems,allowing us to isolate the effects of milliswimmer designs from variations in their physical dimensions.Using this platform,we interrogate established hydrodynamic models of microswimmer locomotion and explore how design and actuation parameters influence milliswimmer velocity.We next explore opportunities for enhancing microswimmer responsiveness,functionality,and physical intelligence through the inclusion of nucleic acid subcomponents.Finally,we highlight how our parallel research on xeno nucleic acids and interfacing DNA nanotechnology with living cells can enable the creation of fully organic,truly biocompatible microswimmers with enhanced functionality,improving the viability of microswimmers for applications in healthcare,manufacturing,and synthetic biology.
基金S.-H.Y.acknowledges the funding support from the National Natural Science Foundation of China(grant nos.21431006 and 21761132008)the Foundation for Innovative Research Groups of the National Natural Science Foundation of China(grant no.21521001)+2 种基金Key Research Program of Frontier Sciences,CAS(grant no.QYZDJ-SSW-SLH036)the Users with Excellence and Scientific Research Grant of Hefei Science Center of CAS(grant no.2015HSC-UE007)O.G.S.is appreciative of the financial support from the Leibniz Program of the German Research Foundation.
文摘Three-dimensional(3D)graphene networks are performance boosters for functional nanostructures in energy-related fields.Although tremendous intriguing nanostructures-decorated 3D graphene networks have been realized,on-demand decoration of nanostructures in the specified position of interest within the whole 3D graphene skeleton is still out of reach,shedding limitations on constructing more sophisticated components with programmable structures which offer enormous potential for the enhancement of performance and exploration of new functions.Here,we report the melamine-sponge(MS)-templated hydrothermal method capable of realizing reduced graphene oxide(RGO)-nanostructure composite aerogels with programmable structures and compositions.The key of this method is using the MS template to preset the structures of choice through programmable solution-processed immobilization of graphene oxide(GO)and nanostructures.Remarkably,the hydrothermal treatment simultaneously removed the MS template and reduced the GO networks without changing the preset structures.We showcased nine typical RGO-nanostructures composite aerogels to demonstrate the versatility of the MS-templated hydrothermal method.
基金the National Natural Science Foundation of China(51732011,51702310,21431006,and 21761132008)the Foundation for Innovative Research Groups of the National Natural Science Foundation of China(21521001)+2 种基金the Key Research Program of Frontier Sciences,CAS(QYZDJ-SSW-SLH036)the Users with Excellence and Scientific Research Grant of Hefei Science Center of CAS(2015HSC-UE007)Anhui Provincial Natural Science Foundation(1808085ME115)。
文摘Conductive and adhesive hydrogels are promising materials for designing bioelectronics.To satisfy the high conductivity of bioelectronic devices,metal nanomaterials have been used to fabricate composite hydrogels.However,the fabrication of a conductive-nanomaterial-incorporated hydrogel with high performance is a great challenge because of the easy aggregation nature of conductive nanomaterials making processing difficult.Here,we report a kind of adhesive aero-hydrogel hybrid conductor(AAHC)with stretchable,adhesive and anti-bacteria properties by in situ formation of a hydrogel network in the aerogel-silver nanowires(AgNWs)assembly.The AgNWs with good conductivity are wellintegrated on the inner-surface of shape-memory chitosan aerogel,which created a conductive framework to allow hydrogel back-filling.Reinforcement by the aerogel-silver makes the hybrid hydrogel tough and stretchable.Functional groups from the hydrogel allow strong adhesion to wet tissues through molecular stitches.The inherent bacteria-killing ability of silver ions endows the conductive hydrogel with excellent anti-bacteria performance.The proposed facile strategy of aerogel-assisted assembly of metal nanomaterials with hydrogel opens a new route to incorporate functional nanoscale building blocks into hydrogels.
基金the National Natural Science Foundation of China (Grant No.20073025), Key Teacher Fund and CSC of Ministry of the Education, State Major Basic Research Project of China and Israel Science Foundation.
文摘The organic lyotropic liquid crystal with long-range structural order is used as template to assemble inorganic/organic hybrid by doping pre-fabricated Ag nanoparticles. The lamellar hybrid with both hydrophilic and hydrophobic particles doped simultaneously is realized for the first time. The change of template structure after doping and the stability origin of dual-doped system are characterized by small angle X-ray scattering and polarized optical microscopy. Results show that the interaction and space matching between surfactant bilayers and doped particles are key factors to obtain stable hybrid.
