Frequent extreme heat events around the world not only pose a major threat to human health but also cause significant economic losses to the livestock industry.The existing management practices are insufficient to ful...Frequent extreme heat events around the world not only pose a major threat to human health but also cause significant economic losses to the livestock industry.The existing management practices are insufficient to fully prevent heat stress with an urgent need to develop preventive medicines.The aim of this study was to develop an antiheat stress Chinese herbal formula(CHF)via big data analysis techniques and to evaluate its anti-heat stress effect and mechanism of action via pharmacodynamic evaluation and network pharmacology analysis.Many anti-heat stress CHFs were collected from the Chinese National Knowledge Infrastructure(CNKI)database.Three alternative CHFs were obtained via unsupervised entropy hierarchical clustering analysis,and the most effective CHF against heat stress,Shidi Jieshu decoction(SJD),was obtained by screening in a mouse heat stress model.In dry and hot environments,SJD significantly improved the heat tolerance of AA broilers by 4-6℃.In a humid and hot environment,pretreatment with 2%SJD resulted in 100%survival of Wenchang chickens at high temperatures.The main active ingredients of SJD were identified as muntjacoside E,timosaponin C,macrostemonoside H and mangiferin via ultraperformance liquid chromatography/mass spectrometry(UPLC/MS)and database comparison.The active ingredients of SJD were found to target tumor necrosis factor-α(TNF-α),signal transducer activator of transcription 3(STAT3)and epidermal growth factor receptor(EGFR).Finally,the safety of the new formulation was assessed in an acute oral toxicity study in rats.The SJDs developed in this study provide a new option for the prevention of heat stress in animal husbandry and offer new insights for further research on anti-heat stress.展开更多
In order to forecast promising technologies in the field of next generation mobile communication, various patent indicators were analyzed such as citation per patent, patent family information, patent share, increase ...In order to forecast promising technologies in the field of next generation mobile communication, various patent indicators were analyzed such as citation per patent, patent family information, patent share, increase rate, and patent activity. These indicators were quantified into several indexes and then integrated into an evaluation score to provide promising technologies. As a result of the suggested patent analysis, four technologies out of twenty two in details classification were selected, which showed outstanding technology competitiveness, high patent share and increasing rates as well as high recent-patent-ratios and triad-patent-family-ratios. Each of the selected technologies scored more than 10 points in total, and the following four technologies were suggested as promising ones in the field of next generation mobile communication: 1) 3GPP based mobile communication, 2) beyond 4G mobile communication, 3) IEEE 802.16 based mobile communication, which are in medium classification of broadband mobile communication system, and 4) testing/certification system of mobile communication, which is in medium classification of mobile communication testing/certification system.展开更多
In this review, we highlight the latest development of multi-channel microfluidic chip-mass spectrometry（chip-MS） in cell analysis and metabolite detection. Following a brief introduction about history and developme...In this review, we highlight the latest development of multi-channel microfluidic chip-mass spectrometry（chip-MS） in cell analysis and metabolite detection. Following a brief introduction about history and development of multi-channel microchip and MS combination, we will elaborate the key issues of constructing chip-MS platform interface. Then exciting progresses made in this field should be reviewed with well exemplified works, including chip-MS technology for cell introduction, pretreatment of cell secretions and cell metabolite analysis. We will also describe the development of integrated total analysis systems proposed by our group. We hope this brief review will inspire interested readers and provide knowledge about chip-MS platform in the bioanalysis field, particularly in cell analysis and metabolite identifying applications.展开更多
Electrodynamic tethered deorbit technology is a novel way to remove abandoned spacecrafts like upper stages or unusable satellites. This paper investigates and analyses the deorbit performance and mission applicabilit...Electrodynamic tethered deorbit technology is a novel way to remove abandoned spacecrafts like upper stages or unusable satellites. This paper investigates and analyses the deorbit performance and mission applicability of the electrodynamic tethered system. To do so, the electrodynamic tethered deorbit dynamics with multi-perturbation is firstly formulated, where the Earth magnetic field, the atmospheric drag, and the Earth oblateness effect are considered. Then, the key system parameters, including payload mass, tether length and tether type, are analyzed by numerical simulations to investigate their influences on the deorbit performance and to give the setting principles for choosing system parameters. Based on this and given an appropriate group of system parameters, numerical simulations are undertaken to study the impact of the mission parameters, including orbit height and orbit inclination, and thus to investigate the mission applicability of the electrodynamic tethered deorbit technology.展开更多
1 GSM-WLL Technology1.1 GSM-WLL System ArchitectureAWLL (Wireless Local Loop)is a radioaccess system for users to access PSTN(Public Switched Telephone Network).It isa substitute for conventional wiredaccess.The GSM-W...1 GSM-WLL Technology1.1 GSM-WLL System ArchitectureAWLL (Wireless Local Loop)is a radioaccess system for users to access PSTN(Public Switched Telephone Network).It isa substitute for conventional wiredaccess.The GSM-WLL system makes use ofGSM technologies to achieve WLL.As shown in Figure 1,a GSM-WLL system展开更多
Background A task assigned to space exploration satellites involves detecting the physical environment within a certain space.However,space detection data are complex and abstract.These data are not conducive for rese...Background A task assigned to space exploration satellites involves detecting the physical environment within a certain space.However,space detection data are complex and abstract.These data are not conducive for researchers'visual perceptions of the evolution and interaction of events in the space environment.Methods A time-series dynamic data sampling method for large-scale space was proposed for sample detection data in space and time,and the corresponding relationships between data location features and other attribute features were established.A tone-mapping method based on statistical histogram equalization was proposed and applied to the final attribute feature data.The visualization process is optimized for rendering by merging materials,reducing the number of patches,and performing other operations.Results The results of sampling,feature extraction,and uniform visualization of the detection data of complex types,long duration spans,and uneven spatial distributions were obtained.The real-time visualization of large-scale spatial structures using augmented reality devices,particularly low-performance devices,was also investigated.Conclusions The proposed visualization system can reconstruct the three-dimensional structure of a large-scale space,express the structure and changes in the spatial environment using augmented reality,and assist in intuitively discovering spatial environmental events and evolutionary rules.展开更多
This paper focuses on the design of fixtures for NP2 and NP4 cylinder heads on a horizontal machining center of flexible machining automatic lines.It began with an analysis of the diagrams of part processing and worki...This paper focuses on the design of fixtures for NP2 and NP4 cylinder heads on a horizontal machining center of flexible machining automatic lines.It began with an analysis of the diagrams of part processing and working procedure which formed the basis for the design of the processing technology scheme,a selection of suitable machine tools,and the setting of processing parameters.Fixtures tailored to the chosen machine tools were then designed to meet the processing requirements.Additional aspects of the project included the design of part drawings,calculation of working time quota,design of auxiliary guides,support clamping,and hydraulic circuits,all aimed at fulfilling practical production requirements.展开更多
Under the background of increasingly scarce ore worldwide and increasingly fierce market competition,developing the mining industry could be strongly restricted.Intelligent ore sorting equipment not only improves ore ...Under the background of increasingly scarce ore worldwide and increasingly fierce market competition,developing the mining industry could be strongly restricted.Intelligent ore sorting equipment not only improves ore use and enhances the economic benefits of enterprises but also increases the ore grade and lessens the grinding cost and tailings production.However,long-term research on intelligent ore sorting equipment found that the factors affecting sorting efficiency mainly include ore information identification technology,equipment sorting actuator,and information processing algorithm.The high precision,strong anti-interference capability,and high speed of these factors guarantee the separation efficiency of intelligent ore sorting equipment.Color ore sorter,X-ray ore transmission sorter,dual-energy X-ray transmission ore sorter,X-ray fluorescence ore sorter,and near-infrared ore sorter have been successfully developed in accordance with the different characteristics of minerals while ensuring the accuracy of equipment sorting and improving the equipment sorting efficiency.With the continuous improvement of mine automation level,the application of online element rapid analysis technology with high speed,high precision,and strong anti-interference capability in intelligent ore sorting equipment will become an inevitable trend of equipment development in the future.Laser-induced breakdown spectroscopy,transientγneutron activation analysis,online Fourier transform infrared spectroscopy,and nuclear magnetic resonance techniques will promote the development of ore sorting equipment.In addition,the improvement and joint application of additional high-speed and high-precision operation algorithms(such as peak area,principal component analysis,artificial neural network,partial least squares,and Monte Carlo library least squares methods)are an essential part of the development of intelligent ore sorting equipment in the future.展开更多
The year of 2011 is considered the first year of big data market in China.Compared with the global scale,China's big data growth will be faster than the global average growth rate,and China will usher in the rapid...The year of 2011 is considered the first year of big data market in China.Compared with the global scale,China's big data growth will be faster than the global average growth rate,and China will usher in the rapid expansion of big data market in the next few years.This paper presents the overall big data development in China in terms of market scale and development stages,enterprise development in the industry chain,the technology standards,and industrial applications.The paper points out the issues and challenges facing big data development in China and proposes to make polices and create support approaches for big data transactions and personal privacy protection.展开更多
Purpose:Measuring the exact technology complementarity between different institutions is necessary to obtain complementary technology resources for R&D cooperation.Design/methodology/approach:This study constructs...Purpose:Measuring the exact technology complementarity between different institutions is necessary to obtain complementary technology resources for R&D cooperation.Design/methodology/approach:This study constructs a morphology-driven method for measuring technology complementarity,taking medical field as an example.First,we calculate semantic similarities between subjects(S and S)and action-objects(AO and AO)based on the Metathesaurus,forming clusters of S and AO based on a semantic similarity matrix.Second,we identify key technology issues and methods based on clusters of S and AO.Third,a technology morphology matrix of several dimensions is constructed using morphology analysis,and the matrix is filled with subjects-action-objects(SAO)structures according to corresponding key technology issues and methods for different institutions.Finally,the technology morphology matrix is used to measure the technology complementarity between different institutions based on SAO.Findings:The improved technology complementarity method based on SAO is more of a supplementary and refined framework for the traditional IPC method.Research limitations:In future studies we will reprocess and identify the SAO structures which were not in the technology morphology matrix,and find other methods to characterize key technical issues and methods.Furthermore,we will add the comparison between proposed method and traditional and mostly used complementarity measurement method based on industry chain and industry code.Practical implications:This study takes medical field as an example.The morphology-driven method for measuring technology complementarity can be migrated and applied for any given field.Originality/value:From the perspective of complementary technology resources,this study develops and tests a more accurate morphology-driven method for technology complementarity measurement.展开更多
The current cost-plus natural gas pricing mechanism makes the gas price too low,resulting in a lot of consumer-side subsidies and over-consumed natural gas.This paper applies the price-gap approach and input-output an...The current cost-plus natural gas pricing mechanism makes the gas price too low,resulting in a lot of consumer-side subsidies and over-consumed natural gas.This paper applies the price-gap approach and input-output analysis technology to quantitatively analyze both the direct and indirect effects on urban residents under the condition that natural gas subsidies are cancelled in China in 2007.It is shown that the gas price will increase by 33.3%-41.6%,and the residential consumption expenditure by 0.26%-0.33%.The low-income groups are mostly affected,so different subsidies should be implemented to make subsidies more efficient.展开更多
This paper describes the analysis and design of an assistive device for elderly people under development at the EgyptJapan University of Science and Technology（E-JUST） named E-JUST assistive device（EJAD）.Several e...This paper describes the analysis and design of an assistive device for elderly people under development at the EgyptJapan University of Science and Technology（E-JUST） named E-JUST assistive device（EJAD）.Several experiments were carried out using a motion capture system（VICON） and inertial sensors to identify the human posture during the sit-to-stand motion.The EJAD uses only two inertial measurement units（IMUs） fused through an adaptive neuro-fuzzy inference systems（ANFIS） algorithm to imitate the real motion of the caregiver.The EJAD consists of two main parts,a robot arm and an active walker.The robot arm is a 2-degree-of-freedom（2-DOF） planar manipulator.In addition,a back support with a passive joint is used to support the patient s back.The IMUs on the leg and trunk of the patient are used to compensate for and adapt to the EJAD system motion depending on the obtained patient posture.The ANFIS algorithm is used to train the fuzzy system that converts the IMUs signals to the right posture of the patient.A control scheme is proposed to control the system motion based on practical measurements taken from the experiments.A computer simulation showed a relatively good performance of the EJAD in assisting the patient.展开更多
On account of the background of China's "new normal" characterized by slower economic growth, this paper analyses the low-carbon economy status quo in the Beijing-Tianjin-Hebei region and empirically inv...On account of the background of China's "new normal" characterized by slower economic growth, this paper analyses the low-carbon economy status quo in the Beijing-Tianjin-Hebei region and empirically investigates the relationship between carbon dioxide(CO_2) emissions and its various factors for China's Beijing-Tianjin-Hebei region using panel data econometric technique. We find evidence of existence of Environmental Kuznets Curve. Results also show that economic scale, industrial structure, and urbanization rate are crucial factors to promote CO_2emissions. However, technological progress, especially the domestic independent research and development, plays a key role in C0_2 emissions abatement. Next, we further analyze the correlation between each subregion and various factors according to Grey Relation Analysis. Thereby,our findings provide important implications for policymakers in air pollution control and C0_2 emissions reduction for this region.展开更多
The differential expression of genes in HepG2 cells caused by UC001 kfo RNAi was investigated using RNA-seq. HepG2 cells were infected by Lenti-sh UC001 kfo lentivirus particles. The expression of UC001 kfo m RNA in t...The differential expression of genes in HepG2 cells caused by UC001 kfo RNAi was investigated using RNA-seq. HepG2 cells were infected by Lenti-sh UC001 kfo lentivirus particles. The expression of UC001 kfo m RNA in the HepG2-sh UC001 kfo cell line was detected by real-time PCR. RNA-seq technology was used to identify the difference in the expression of genes regulated by lnc RNA UC001 kfo in the HepG2 cell line. Gene ontology and signaling pathway analysis were performed to reveal the biological functions of the genes encoding of significantly different m RNAs. The results showed that m RNAs were differentially expressed between the HepG2-sh UC001 kfo cell line and the HepG2 cell line. The UC001 kfo m RNA was significantly down-regulated in the stable cell line HepG2-sh UC001kfo（P〈0.001）. Additionally, we found 19 signaling pathways or functional classifications encompassing 30 genes that played a role in cancer characteristics, cell adhesion, invasion and migration. The results also showed that the expression of many genes associated with cancer cell invasion and metastasis was decreased with the down-regulation of the lnc RNA UC001 kfo. Lnc RNA UC001 kfo may play a role in regulating cancer cell invasion and metastasis. It was suggested that m RNAs were differentially expressed in the HepG2 cell line after the down-regulation of lnc RNA-UC001 kfo. Some took part in the extracellular matrix, cell adhesion, motility, growth, and localization. The genes encoding of differentially expressed m RNAs may participate in cell invasion and metastasis.展开更多
The roles of slightly crosslinked poly( dimethyldiallylammonium chloride) s( PDMDAACs) in fixing anionic dyes on cotton fabric were verified more precisely by optical analysis technologies,to achieve the new theoretic...The roles of slightly crosslinked poly( dimethyldiallylammonium chloride) s( PDMDAACs) in fixing anionic dyes on cotton fabric were verified more precisely by optical analysis technologies,to achieve the new theoretical guides for the widely applications. Firstly,one method of optical CIELAB color difference analysis was designed to exactly measure the values of dyefixing performances, so that the suitable molecular weights and structures of the slightly crosslinked PDMDAACs could be precisely confirmed to play a role in the development of their dye-fixing performances. Secondly,the FT-IR absorption shift of the dye on dyed cotton sample fixed by slightly crosslinked PDMDAACs was nearly in agreement with that of forming water-insoluble color lakes,indicating that the expected color lakes could be formed on dyed cotton fabric,and would play a role in further development of the fastness of dyes on cotton fabric. Thirdly,the FT-IR spectra of fixed undyed cotton samples and that of fixed dyed cotton samples both showed the absorptions of slightly crosslinked PDMDAACs,further revealing that the slightly crosslinked PDMDAACs could be penetrated into cotton fabric and be convenient to interact with dyes when fixing. However,those absorptions of the slightly crosslinked PDMDAACs fixed on cotton samples would be absent after being adequately washed to a constant weight,suggesting that the fixing interactions of the slightly crosslinked PDMDAAC and cotton fabric were very weak.展开更多
The paper conducts analysis on the causes of dangerous goods road transportation accidents by applying analytic technique of security system science - Event Tree Analysis （ETA）. By computing minimum cut and minimal ...The paper conducts analysis on the causes of dangerous goods road transportation accidents by applying analytic technique of security system science - Event Tree Analysis （ETA）. By computing minimum cut and minimal path set of event tree and the important level of elementary event, the paper elicits the results that the factors of causing road transportation accident are multiple and its hazard is great while the paper also elicits the sorting of structural important level of elementary event. The paper offers the security countermeasures for dangerous goods road transportation which plays a vital role in safeguarding dangerous goods road transportation security.展开更多
From the author, there are not less than a dozen of rather significant recent publications in scientific editions anticipating some aspects of importance to innovation such as “bigger data”, AI, IP, and frontier tec...From the author, there are not less than a dozen of rather significant recent publications in scientific editions anticipating some aspects of importance to innovation such as “bigger data”, AI, IP, and frontier technology with a central massive contribution in 2020 on AI, IP, and EI. Nonetheless, the IP associated with AI remains still barely covered in scientific publications. Especially patent discussion tends to be rather a legal matter. Another trilogy, 2013, “Business Strategy-IP Strategy-R&D Strategy: An All-in-One Business Model” proposed by the author, marked the advent, and customized implementation of a new strategy level. After the two trilogies’ volumes, the AI-IP “accessibility” chapter was a logical step brought to the attention of a larger public by the author. The time now to bring to light another chapter, namely the IP eligibility of AI innovation steps in ad hoc inventions. The main objectives of this short, principally illustrated communication, are to: 1) Revise the best mode requirement status, i.e. the best way to enable the reproducibility of claimed matter, reviewing its need for improvement when AI is involved. And proposing a unique sequence of evolution inspired by IP’s current and evolving practices. 2) Give a new dimension to visual aids to help the Best Mode description, demystify AI complexity, and underline frontier traits that may hinder a confident adoption or well-argued rejection. 3) Further illustrations take into account the fact that IoT, AI, and 3D can be simpler than perceived. 4) Finally ATA©, Adjacent Technology Analysis, is timely refreshed in a unique challenging, indeed tumultuous, environment. 5) Bias, such as semantic ones is consistently monitored. 6) Overall leaving space for innovative pleasurable interpretation. The emphasis is on educational, illustrative and demonstrative value.展开更多
Today＇s emergence of nano-micro hybrid structures with almost biological complexity is of fundamental interest. Our ability to adapt intelligently to the challenges has ramifications all the way from fundamentally ch...Today＇s emergence of nano-micro hybrid structures with almost biological complexity is of fundamental interest. Our ability to adapt intelligently to the challenges has ramifications all the way from fundamentally changing research itself, over applications critical to future survival, to posing globally existential dangers. Touching on specific issues such as how complexity relates to the catalytic prowess of multi-metal compounds, we discuss the increasingly urgent issues in nanotechnology also very generally and guided by the motto ＇Bio Is Nature＇s Nanotech＇. Technology belongs to macro-evolution; for example integration with artificial intelligence （AI） is inevitable. Darwinian adaptation manifests as integration of complexity, and awareness of this helps in developing adaptable research methods that can find use across a wide range of research. The second half of this work reviews a diverse range of projects which all benefited from ＇playful＇ programming aimed at dealing with complexity. The main purpose of reviewing them is to show how such projects benefit from and fit in with the general, philosophical approach, proving the relevance of the ＇big picture＇ where it is usually disregarded.展开更多
基金supported by the Major Special Science and Technology Plan(202302AA310020)the National Natural Science Foundation of China(NSFC)(32072925,32473087)the National Student Innovation and Entrepreneurship Training Program of Huazhong Agricultural University(202310504018)。
文摘Frequent extreme heat events around the world not only pose a major threat to human health but also cause significant economic losses to the livestock industry.The existing management practices are insufficient to fully prevent heat stress with an urgent need to develop preventive medicines.The aim of this study was to develop an antiheat stress Chinese herbal formula(CHF)via big data analysis techniques and to evaluate its anti-heat stress effect and mechanism of action via pharmacodynamic evaluation and network pharmacology analysis.Many anti-heat stress CHFs were collected from the Chinese National Knowledge Infrastructure(CNKI)database.Three alternative CHFs were obtained via unsupervised entropy hierarchical clustering analysis,and the most effective CHF against heat stress,Shidi Jieshu decoction(SJD),was obtained by screening in a mouse heat stress model.In dry and hot environments,SJD significantly improved the heat tolerance of AA broilers by 4-6℃.In a humid and hot environment,pretreatment with 2%SJD resulted in 100%survival of Wenchang chickens at high temperatures.The main active ingredients of SJD were identified as muntjacoside E,timosaponin C,macrostemonoside H and mangiferin via ultraperformance liquid chromatography/mass spectrometry(UPLC/MS)and database comparison.The active ingredients of SJD were found to target tumor necrosis factor-α(TNF-α),signal transducer activator of transcription 3(STAT3)and epidermal growth factor receptor(EGFR).Finally,the safety of the new formulation was assessed in an acute oral toxicity study in rats.The SJDs developed in this study provide a new option for the prevention of heat stress in animal husbandry and offer new insights for further research on anti-heat stress.
文摘In order to forecast promising technologies in the field of next generation mobile communication, various patent indicators were analyzed such as citation per patent, patent family information, patent share, increase rate, and patent activity. These indicators were quantified into several indexes and then integrated into an evaluation score to provide promising technologies. As a result of the suggested patent analysis, four technologies out of twenty two in details classification were selected, which showed outstanding technology competitiveness, high patent share and increasing rates as well as high recent-patent-ratios and triad-patent-family-ratios. Each of the selected technologies scored more than 10 points in total, and the following four technologies were suggested as promising ones in the field of next generation mobile communication: 1) 3GPP based mobile communication, 2) beyond 4G mobile communication, 3) IEEE 802.16 based mobile communication, which are in medium classification of broadband mobile communication system, and 4) testing/certification system of mobile communication, which is in medium classification of mobile communication testing/certification system.
基金supported by National Natural Science Foundation of China (Nos. 81373373, 21435002, 21621003)
文摘In this review, we highlight the latest development of multi-channel microfluidic chip-mass spectrometry（chip-MS） in cell analysis and metabolite detection. Following a brief introduction about history and development of multi-channel microchip and MS combination, we will elaborate the key issues of constructing chip-MS platform interface. Then exciting progresses made in this field should be reviewed with well exemplified works, including chip-MS technology for cell introduction, pretreatment of cell secretions and cell metabolite analysis. We will also describe the development of integrated total analysis systems proposed by our group. We hope this brief review will inspire interested readers and provide knowledge about chip-MS platform in the bioanalysis field, particularly in cell analysis and metabolite identifying applications.
文摘Electrodynamic tethered deorbit technology is a novel way to remove abandoned spacecrafts like upper stages or unusable satellites. This paper investigates and analyses the deorbit performance and mission applicability of the electrodynamic tethered system. To do so, the electrodynamic tethered deorbit dynamics with multi-perturbation is firstly formulated, where the Earth magnetic field, the atmospheric drag, and the Earth oblateness effect are considered. Then, the key system parameters, including payload mass, tether length and tether type, are analyzed by numerical simulations to investigate their influences on the deorbit performance and to give the setting principles for choosing system parameters. Based on this and given an appropriate group of system parameters, numerical simulations are undertaken to study the impact of the mission parameters, including orbit height and orbit inclination, and thus to investigate the mission applicability of the electrodynamic tethered deorbit technology.
文摘1 GSM-WLL Technology1.1 GSM-WLL System ArchitectureAWLL (Wireless Local Loop)is a radioaccess system for users to access PSTN(Public Switched Telephone Network).It isa substitute for conventional wiredaccess.The GSM-WLL system makes use ofGSM technologies to achieve WLL.As shown in Figure 1,a GSM-WLL system
文摘Background A task assigned to space exploration satellites involves detecting the physical environment within a certain space.However,space detection data are complex and abstract.These data are not conducive for researchers'visual perceptions of the evolution and interaction of events in the space environment.Methods A time-series dynamic data sampling method for large-scale space was proposed for sample detection data in space and time,and the corresponding relationships between data location features and other attribute features were established.A tone-mapping method based on statistical histogram equalization was proposed and applied to the final attribute feature data.The visualization process is optimized for rendering by merging materials,reducing the number of patches,and performing other operations.Results The results of sampling,feature extraction,and uniform visualization of the detection data of complex types,long duration spans,and uneven spatial distributions were obtained.The real-time visualization of large-scale spatial structures using augmented reality devices,particularly low-performance devices,was also investigated.Conclusions The proposed visualization system can reconstruct the three-dimensional structure of a large-scale space,express the structure and changes in the spatial environment using augmented reality,and assist in intuitively discovering spatial environmental events and evolutionary rules.
文摘This paper focuses on the design of fixtures for NP2 and NP4 cylinder heads on a horizontal machining center of flexible machining automatic lines.It began with an analysis of the diagrams of part processing and working procedure which formed the basis for the design of the processing technology scheme,a selection of suitable machine tools,and the setting of processing parameters.Fixtures tailored to the chosen machine tools were then designed to meet the processing requirements.Additional aspects of the project included the design of part drawings,calculation of working time quota,design of auxiliary guides,support clamping,and hydraulic circuits,all aimed at fulfilling practical production requirements.
基金supported by the National Science and Technology Support Program of China(No.2012BAC11B07)the Jiangxi Science and Technology Innovation Base Plan(No.20212BCD42017)。
文摘Under the background of increasingly scarce ore worldwide and increasingly fierce market competition,developing the mining industry could be strongly restricted.Intelligent ore sorting equipment not only improves ore use and enhances the economic benefits of enterprises but also increases the ore grade and lessens the grinding cost and tailings production.However,long-term research on intelligent ore sorting equipment found that the factors affecting sorting efficiency mainly include ore information identification technology,equipment sorting actuator,and information processing algorithm.The high precision,strong anti-interference capability,and high speed of these factors guarantee the separation efficiency of intelligent ore sorting equipment.Color ore sorter,X-ray ore transmission sorter,dual-energy X-ray transmission ore sorter,X-ray fluorescence ore sorter,and near-infrared ore sorter have been successfully developed in accordance with the different characteristics of minerals while ensuring the accuracy of equipment sorting and improving the equipment sorting efficiency.With the continuous improvement of mine automation level,the application of online element rapid analysis technology with high speed,high precision,and strong anti-interference capability in intelligent ore sorting equipment will become an inevitable trend of equipment development in the future.Laser-induced breakdown spectroscopy,transientγneutron activation analysis,online Fourier transform infrared spectroscopy,and nuclear magnetic resonance techniques will promote the development of ore sorting equipment.In addition,the improvement and joint application of additional high-speed and high-precision operation algorithms(such as peak area,principal component analysis,artificial neural network,partial least squares,and Monte Carlo library least squares methods)are an essential part of the development of intelligent ore sorting equipment in the future.
文摘The year of 2011 is considered the first year of big data market in China.Compared with the global scale,China's big data growth will be faster than the global average growth rate,and China will usher in the rapid expansion of big data market in the next few years.This paper presents the overall big data development in China in terms of market scale and development stages,enterprise development in the industry chain,the technology standards,and industrial applications.The paper points out the issues and challenges facing big data development in China and proposes to make polices and create support approaches for big data transactions and personal privacy protection.
基金This work was supported by the General Program of National Natural Science Foundation of China under(Grant Nos.71774012,72104246,71673024)the Fundamental Research Funds for the Central Universities(22CX04010B)the strategic research project of the Development Planning Bureau of the Chinese Academy of Sciences(Grant No.GHJ-ZLZX-2019-42).The findings and observations in this paper are those of the authors and do not necessarily reflect the views of the supporters.
文摘Purpose:Measuring the exact technology complementarity between different institutions is necessary to obtain complementary technology resources for R&D cooperation.Design/methodology/approach:This study constructs a morphology-driven method for measuring technology complementarity,taking medical field as an example.First,we calculate semantic similarities between subjects(S and S)and action-objects(AO and AO)based on the Metathesaurus,forming clusters of S and AO based on a semantic similarity matrix.Second,we identify key technology issues and methods based on clusters of S and AO.Third,a technology morphology matrix of several dimensions is constructed using morphology analysis,and the matrix is filled with subjects-action-objects(SAO)structures according to corresponding key technology issues and methods for different institutions.Finally,the technology morphology matrix is used to measure the technology complementarity between different institutions based on SAO.Findings:The improved technology complementarity method based on SAO is more of a supplementary and refined framework for the traditional IPC method.Research limitations:In future studies we will reprocess and identify the SAO structures which were not in the technology morphology matrix,and find other methods to characterize key technical issues and methods.Furthermore,we will add the comparison between proposed method and traditional and mostly used complementarity measurement method based on industry chain and industry code.Practical implications:This study takes medical field as an example.The morphology-driven method for measuring technology complementarity can be migrated and applied for any given field.Originality/value:From the perspective of complementary technology resources,this study develops and tests a more accurate morphology-driven method for technology complementarity measurement.
基金Supported by Strategic Priority Research Program of Chinese Academy of Sciences (No. XDA05150600)National Natural Science Foundation of China (No. 71041006 and No. 70903066)
文摘The current cost-plus natural gas pricing mechanism makes the gas price too low,resulting in a lot of consumer-side subsidies and over-consumed natural gas.This paper applies the price-gap approach and input-output analysis technology to quantitatively analyze both the direct and indirect effects on urban residents under the condition that natural gas subsidies are cancelled in China in 2007.It is shown that the gas price will increase by 33.3%-41.6%,and the residential consumption expenditure by 0.26%-0.33%.The low-income groups are mostly affected,so different subsidies should be implemented to make subsidies more efficient.
基金supported in part by a scholarship provided by the Mission DepartmentMinistry of Higher Education of the Government of Egypt
文摘This paper describes the analysis and design of an assistive device for elderly people under development at the EgyptJapan University of Science and Technology（E-JUST） named E-JUST assistive device（EJAD）.Several experiments were carried out using a motion capture system（VICON） and inertial sensors to identify the human posture during the sit-to-stand motion.The EJAD uses only two inertial measurement units（IMUs） fused through an adaptive neuro-fuzzy inference systems（ANFIS） algorithm to imitate the real motion of the caregiver.The EJAD consists of two main parts,a robot arm and an active walker.The robot arm is a 2-degree-of-freedom（2-DOF） planar manipulator.In addition,a back support with a passive joint is used to support the patient s back.The IMUs on the leg and trunk of the patient are used to compensate for and adapt to the EJAD system motion depending on the obtained patient posture.The ANFIS algorithm is used to train the fuzzy system that converts the IMUs signals to the right posture of the patient.A control scheme is proposed to control the system motion based on practical measurements taken from the experiments.A computer simulation showed a relatively good performance of the EJAD in assisting the patient.
基金supported by National Social Science Foundation Project of China-A study on the Long-term Mechanism and Policy of Promoting the Construction of Ecological Civilization with Green Technological Innovation in China:[Grant Number 14AJL017]
文摘On account of the background of China's "new normal" characterized by slower economic growth, this paper analyses the low-carbon economy status quo in the Beijing-Tianjin-Hebei region and empirically investigates the relationship between carbon dioxide(CO_2) emissions and its various factors for China's Beijing-Tianjin-Hebei region using panel data econometric technique. We find evidence of existence of Environmental Kuznets Curve. Results also show that economic scale, industrial structure, and urbanization rate are crucial factors to promote CO_2emissions. However, technological progress, especially the domestic independent research and development, plays a key role in C0_2 emissions abatement. Next, we further analyze the correlation between each subregion and various factors according to Grey Relation Analysis. Thereby,our findings provide important implications for policymakers in air pollution control and C0_2 emissions reduction for this region.
基金supported by National Natural Science Foudation of China(No.U1404309)
文摘The differential expression of genes in HepG2 cells caused by UC001 kfo RNAi was investigated using RNA-seq. HepG2 cells were infected by Lenti-sh UC001 kfo lentivirus particles. The expression of UC001 kfo m RNA in the HepG2-sh UC001 kfo cell line was detected by real-time PCR. RNA-seq technology was used to identify the difference in the expression of genes regulated by lnc RNA UC001 kfo in the HepG2 cell line. Gene ontology and signaling pathway analysis were performed to reveal the biological functions of the genes encoding of significantly different m RNAs. The results showed that m RNAs were differentially expressed between the HepG2-sh UC001 kfo cell line and the HepG2 cell line. The UC001 kfo m RNA was significantly down-regulated in the stable cell line HepG2-sh UC001kfo（P〈0.001）. Additionally, we found 19 signaling pathways or functional classifications encompassing 30 genes that played a role in cancer characteristics, cell adhesion, invasion and migration. The results also showed that the expression of many genes associated with cancer cell invasion and metastasis was decreased with the down-regulation of the lnc RNA UC001 kfo. Lnc RNA UC001 kfo may play a role in regulating cancer cell invasion and metastasis. It was suggested that m RNAs were differentially expressed in the HepG2 cell line after the down-regulation of lnc RNA-UC001 kfo. Some took part in the extracellular matrix, cell adhesion, motility, growth, and localization. The genes encoding of differentially expressed m RNAs may participate in cell invasion and metastasis.
基金Science and Technology Project of Education Department of Jiangxi Province,China(No.GJJ13213)
文摘The roles of slightly crosslinked poly( dimethyldiallylammonium chloride) s( PDMDAACs) in fixing anionic dyes on cotton fabric were verified more precisely by optical analysis technologies,to achieve the new theoretical guides for the widely applications. Firstly,one method of optical CIELAB color difference analysis was designed to exactly measure the values of dyefixing performances, so that the suitable molecular weights and structures of the slightly crosslinked PDMDAACs could be precisely confirmed to play a role in the development of their dye-fixing performances. Secondly,the FT-IR absorption shift of the dye on dyed cotton sample fixed by slightly crosslinked PDMDAACs was nearly in agreement with that of forming water-insoluble color lakes,indicating that the expected color lakes could be formed on dyed cotton fabric,and would play a role in further development of the fastness of dyes on cotton fabric. Thirdly,the FT-IR spectra of fixed undyed cotton samples and that of fixed dyed cotton samples both showed the absorptions of slightly crosslinked PDMDAACs,further revealing that the slightly crosslinked PDMDAACs could be penetrated into cotton fabric and be convenient to interact with dyes when fixing. However,those absorptions of the slightly crosslinked PDMDAACs fixed on cotton samples would be absent after being adequately washed to a constant weight,suggesting that the fixing interactions of the slightly crosslinked PDMDAAC and cotton fabric were very weak.
文摘The paper conducts analysis on the causes of dangerous goods road transportation accidents by applying analytic technique of security system science - Event Tree Analysis （ETA）. By computing minimum cut and minimal path set of event tree and the important level of elementary event, the paper elicits the results that the factors of causing road transportation accident are multiple and its hazard is great while the paper also elicits the sorting of structural important level of elementary event. The paper offers the security countermeasures for dangerous goods road transportation which plays a vital role in safeguarding dangerous goods road transportation security.
文摘From the author, there are not less than a dozen of rather significant recent publications in scientific editions anticipating some aspects of importance to innovation such as “bigger data”, AI, IP, and frontier technology with a central massive contribution in 2020 on AI, IP, and EI. Nonetheless, the IP associated with AI remains still barely covered in scientific publications. Especially patent discussion tends to be rather a legal matter. Another trilogy, 2013, “Business Strategy-IP Strategy-R&D Strategy: An All-in-One Business Model” proposed by the author, marked the advent, and customized implementation of a new strategy level. After the two trilogies’ volumes, the AI-IP “accessibility” chapter was a logical step brought to the attention of a larger public by the author. The time now to bring to light another chapter, namely the IP eligibility of AI innovation steps in ad hoc inventions. The main objectives of this short, principally illustrated communication, are to: 1) Revise the best mode requirement status, i.e. the best way to enable the reproducibility of claimed matter, reviewing its need for improvement when AI is involved. And proposing a unique sequence of evolution inspired by IP’s current and evolving practices. 2) Give a new dimension to visual aids to help the Best Mode description, demystify AI complexity, and underline frontier traits that may hinder a confident adoption or well-argued rejection. 3) Further illustrations take into account the fact that IoT, AI, and 3D can be simpler than perceived. 4) Finally ATA©, Adjacent Technology Analysis, is timely refreshed in a unique challenging, indeed tumultuous, environment. 5) Bias, such as semantic ones is consistently monitored. 6) Overall leaving space for innovative pleasurable interpretation. The emphasis is on educational, illustrative and demonstrative value.
基金jointly supported by the Natural Science Foundation of Jiangsu Province (No.2012729)the Innovation Fund of Jiangsu Province (No.BY2013072-06)the National Natural Science Foundation of China (No.51171078 and No.11374136)
文摘Today＇s emergence of nano-micro hybrid structures with almost biological complexity is of fundamental interest. Our ability to adapt intelligently to the challenges has ramifications all the way from fundamentally changing research itself, over applications critical to future survival, to posing globally existential dangers. Touching on specific issues such as how complexity relates to the catalytic prowess of multi-metal compounds, we discuss the increasingly urgent issues in nanotechnology also very generally and guided by the motto ＇Bio Is Nature＇s Nanotech＇. Technology belongs to macro-evolution; for example integration with artificial intelligence （AI） is inevitable. Darwinian adaptation manifests as integration of complexity, and awareness of this helps in developing adaptable research methods that can find use across a wide range of research. The second half of this work reviews a diverse range of projects which all benefited from ＇playful＇ programming aimed at dealing with complexity. The main purpose of reviewing them is to show how such projects benefit from and fit in with the general, philosophical approach, proving the relevance of the ＇big picture＇ where it is usually disregarded.
