期刊文献+
共找到707,379篇文章
< 1 2 250 >
每页显示 20 50 100
High-fidelity Lumped-parameter Thermal Models for Assessing Cooling Techniques of PMSMs in EV Applications 被引量:2
1
作者 Dawei Liang Zi Qiang Zhu Ankan Dey 《CES Transactions on Electrical Machines and Systems》 2025年第1期1-14,共14页
This paper presents a high-fidelity lumpedparameter(LP)thermal model(HF-LPTM)for permanent magnet synchronous machines(PMSMs)in electric vehicle(EV)applications,where various cooling techniques are considered,includin... This paper presents a high-fidelity lumpedparameter(LP)thermal model(HF-LPTM)for permanent magnet synchronous machines(PMSMs)in electric vehicle(EV)applications,where various cooling techniques are considered,including frame forced air/liquid cooling,oil jet cooling for endwinding,and rotor shaft cooling.To address the temperature misestimation in the LP thermal modelling due to assumptions of concentrated loss input and uniform heat flows,the developed HF-LPTM introduces two compensation thermal resistances for the winding and PM components,which are analytically derived from the multi-dimensional heat transfer equations and are robust against different load/thermal conditions.As validated by the finite element analysis method and experiments,the conventional LPTMs exhibit significant winding temperature deviations,while the proposed HF-LPTM can accurately predict both the midpoint and average temperatures.The developed HFLPTM is further used to assess the effectiveness of various cooling techniques under different scenarios,i.e.,steady-state thermal states under the rated load condition,and transient temperature profiles under city,freeway,and hybrid(city+freeway)driving cycles.Results indicate that no single cooling technique can maintain both winding and PM temperatures within safety limits.The combination of frame liquid cooling and oil jet cooling for end winding can sufficiently mitigate PMSM thermal stress in EV applications. 展开更多
关键词 Cooling techniques Electric vehicle Lumpedparameter thermal model Permanent magnet synchronous machines Thermal analysis Thermal management
在线阅读 下载PDF
Study on Cultivation Techniques of Spring Soybean for High Quality and High and Stable Yield in Huang-Huai Area
2
作者 Huajun SUN 《Agricultural Biotechnology》 2025年第2期25-28,共4页
As an important grain and oil crop,soybean occupies an important position in China s agricultural production.High quality and stable yield of spring soybean is of great significance for ensuring food security and incr... As an important grain and oil crop,soybean occupies an important position in China s agricultural production.High quality and stable yield of spring soybean is of great significance for ensuring food security and increasing farmers income.Based on the planting experience and scientific research achievements in many regions,this paper systematically expounded a series of cultivation techniques of spring soybean with high quality and high yield from variety selection,preparation before sowing,sowing techniques,field management to disease and pest control and harvest and storage,aiming to provide scientific and comprehensive guidance for soybean growers and promote the development of soybean industry. 展开更多
关键词 Spring soybean high quality high yield Stable yield Cultivation technique
在线阅读 下载PDF
High-quality and High-yield Cultivation Techniques for Summer Soybean
3
作者 Huajun SUN Kun CHEN Ruhong FU 《Agricultural Biotechnology》 2025年第3期29-32,共4页
Soybeans are rich in protein,fats,vitamins,and minerals,serving as an important source of plant-based protein for humans.Summer soybean is widely cultivated in China,and improving its yield and quality is of great sig... Soybeans are rich in protein,fats,vitamins,and minerals,serving as an important source of plant-based protein for humans.Summer soybean is widely cultivated in China,and improving its yield and quality is of great significance for ensuring food security and promoting agricultural economic development.This paper elaborated on the high-quality and high-yield cultivation techniques for summer soybean,including variety selection,seed treatment,field selection and land preparation,sowing techniques,field management,pest and disease control,and harvesting,aiming to provide scientific cultivation guidance for summer soybean growers to achieve both superior quality and high yield. 展开更多
关键词 Summer soybean high quality high yield Cultivation technique
在线阅读 下载PDF
High-precision ADC design techniques in ISSCC 2025
4
作者 Bingrui Li Zongnan Wang Xiyuan Tang 《Journal of Semiconductors》 2025年第7期16-20,共5页
High-precision analog-to-digital converters(ADCs)serve as fundamental components in modern electronic systems,bridging physical analog world and digital intelligence.They find ubiquitous applications across diverse do... High-precision analog-to-digital converters(ADCs)serve as fundamental components in modern electronic systems,bridging physical analog world and digital intelligence.They find ubiquitous applications across diverse domains,ranging from internet of things(IoT)to embodied artificial intelligence systems.Achieving high precision necessitates various circuit techniques including high-performance amplifiers and advanced calibration schemes.Furthermore,the evolution of ADC architectures has gradually elevated the significance of peripheral circuitry co-design in optimizing system-level performance metrics.In ISSCC 2025,several techniques are proposed to address these challenges. 展开更多
关键词 circuit techniques internet things iot analog digital converters modern electronic systemsbridging internet things embodied artificial intelligence high precision adc embodied artificial intelligence systemsachieving
在线阅读 下载PDF
Research Status and Prospects of Platinum Group Metal Coatings with High-Temperature Oxidation Resistance
5
作者 Ding Chenxi Liu Zhongyu +3 位作者 Fang Zhen Wang Haoxu Lv Biao Hu Zhenfeng 《稀有金属材料与工程》 北大核心 2026年第2期333-344,共12页
Platinum group metals have high melting points,strong corrosion resistance,stable chemical properties,and low oxygen permeability in high-temperature oxygen-containing environments.As thermal protective coating materi... Platinum group metals have high melting points,strong corrosion resistance,stable chemical properties,and low oxygen permeability in high-temperature oxygen-containing environments.As thermal protective coating materials,they have gained essential applications in the aerospace field and have excellent prospects for application in frontier military fields,such as protecting hot-end components of hypersonic aircraft.This research reviewed the latest research progress of platinum group metal coatings with hightemperature oxidation resistance,including coating preparation techniques,oxidation failure,and alloying modification.The leading preparation techniques of current platinum group metal coatings were discussed,as well as the advantages and disadvantages of various existing preparation techniques.Besides,the intrinsic properties,failure forms,and failure mechanisms of coatings of single platinum group metal in high-temperature oxygen-containing environments were analyzed.On this basis,the necessity,main methods,and main achievements of alloying modification of platinum group metals were summarized.Finally,the future development of platinum group coatings with high-temperature oxidation resistance was discussed and prospected. 展开更多
关键词 platinum group metal coatings preparation technique high temperature oxidation resistance alloying modification
原文传递
Research Progress on High-efficiency Cultivation Techniques of Blueberry and Its Development Potential in Under-forest Economy
6
作者 Haineng LIN Yuzhen YU +1 位作者 Hubo JIANG Ting ZHANG 《Asian Agricultural Research》 2025年第7期12-16,共5页
Through literature analysis and case study, the introduction history, variety selection (high bush, half high bush, low bush) and regional cultivation techniques of blueberry in China were summarized, and the practica... Through literature analysis and case study, the introduction history, variety selection (high bush, half high bush, low bush) and regional cultivation techniques of blueberry in China were summarized, and the practical effects of precision cultivation (water and fertilizer integration, wild planting) and under-forest economic model (forest-blueberry-fungus system, ecological tourism) were evaluated. It provided a technical reference for expanding the planting scale of blueberry and improving the fruit quality. 展开更多
关键词 BLUEBERRY high-efficiency cultivation techniques Under-forest economy Rural revitalization
在线阅读 下载PDF
Breeding and Cultivation Techniques of a New High-Yield Spring Soybean Cultivar‘Xiangchundou 36’
7
作者 JIANG Ling ZHOU Zhi-ping +3 位作者 YANG Xiao-feng LI Dong-hao CHEN Yuan-wei ZHOU Hong 《Agricultural Science & Technology》 2025年第1期1-6,共6页
‘Xiangchundou 36’is a new high-yield spring soybean cultivar bred by the Crop Research Institute of Hunan Province.This cultivar was bred in 2014 by the pedigree method with‘Xiangchundou V7’as the male parent and... ‘Xiangchundou 36’is a new high-yield spring soybean cultivar bred by the Crop Research Institute of Hunan Province.This cultivar was bred in 2014 by the pedigree method with‘Xiangchundou V7’as the male parent and‘Youchun 1204’as the female parent.The cultivar showed high yields and excellent comprehensive traits in all levels of tests carried out from 2019 to 2023.In 2024,it was approved by Hunan Provincial Crop Variety Certification Committee,with the certification number Xiangshendou 20241004.‘Xiangchundou 36’was suitable for planting as a spring soybean cultivar in Hunan Province. 展开更多
关键词 ‘Xiangchundou 36’ Cultivar breeding Cultivation technique
在线阅读 下载PDF
Intensive Planting and High Yield Cultivation Techniques for Yuluxiang Pear in Hilly and Mountainous Regions
8
作者 Liping XUE 《Plant Diseases and Pests》 2025年第1期31-33,共3页
In order to enhance the guidance for Yuluxiang pear cultivation in hilly and mountainous regions, this study provides a comprehensive introduction to various aspects, including the establishment of high-standard orcha... In order to enhance the guidance for Yuluxiang pear cultivation in hilly and mountainous regions, this study provides a comprehensive introduction to various aspects, including the establishment of high-standard orchards and the reinforcement of integrated management techniques, in order to offer a valuable reference for fruit farmers engaged in scientific planting practices. 展开更多
关键词 Yuluxiang pear high yield Intensive planting CULTIVATION
在线阅读 下载PDF
High-Entropy Materials:A New Paradigm in the Design of Advanced Batteries
9
作者 Yangmei Xin Minmin Zhu +1 位作者 Haizhong Zhang Xinghui Wang 《Nano-Micro Letters》 2026年第1期1-52,共52页
High-entropy materials(HEMs)have attracted considerable research attention in battery applications due to exceptional properties such as remarkable structural stability,enhanced ionic conductivity,superior mechanical ... High-entropy materials(HEMs)have attracted considerable research attention in battery applications due to exceptional properties such as remarkable structural stability,enhanced ionic conductivity,superior mechanical strength,and outstanding catalytic activity.These distinctive characteristics render HEMs highly suitable for various battery components,such as electrodes,electrolytes,and catalysts.This review systematically examines recent advances in the application of HEMs for energy storage,beginning with fundamental concepts,historical development,and key definitions.Three principal categories of HEMs,namely high-entropy alloys,high-entropy oxides,and highentropy MXenes,are analyzed with a focus on electrochemical performance metrics such as specific capacity,energy density,cycling stability,and rate capability.The underlying mechanisms by which these materials enhance battery performance are elucidated in the discussion.Furthermore,the pivotal role of machine learning in accelerating the discovery and optimization of novel high-entropy battery materials is highlighted.The review concludes by outlining future research directions and potential breakthroughs in HEM-based battery technologies. 展开更多
关键词 high entropy alloys high entropy oxides high entropy MXenes high entropy battery materials Machine learning
在线阅读 下载PDF
Prospects and potential mechanism of appropriate traditional Chinese medicine techniques for myopia treatment
10
作者 Hui-Min Guo Hong-Mei Li Shu-Li Man 《Traditional Medicine Research》 2026年第1期100-114,共15页
Currently,the number of patients with myopia is increasing rapidly across the globe.Traditional Chinese medicine(TCM),with its long history and rich experience,has shown promise in effectively managing and treating th... Currently,the number of patients with myopia is increasing rapidly across the globe.Traditional Chinese medicine(TCM),with its long history and rich experience,has shown promise in effectively managing and treating this condition.Nevertheless,considering the vast amount of research that is currently being conducted,focusing on the utilization of TCM in the management of myopia,there is an urgent requirement for a thorough and comprehensive review.The review would serve to clarify the practical applications of TCM within this specific field,and it would also aim to elucidate the underlying mechanisms that are at play,providing a deeper understanding of how TCM principles can be effectively integrated into modern medical practices.Here,some modern medical pathogenesis of myopia and appropriate TCM techniques studies are summarized in the prevention and treatment of myopia.Further,we discussed the potential mechanisms and the future research directions of TCM against myopia.Identifying these mechanisms is crucial for understanding how TCM can be effectively utilized in this context.The combination of various TCM methods or the combination of traditional Chinese and Western medicine is of great significance for the prevention and control of myopia in the future. 展开更多
关键词 traditional Chinese medicine MYOPIA PATHOGENESIS appropriate TCM techniques
暂未订购
A Comprehensive Literature Review of AI-Driven Application Mapping and Scheduling Techniques for Network-on-Chip Systems
11
作者 Naveed Ahmad Muhammad Kaleem +5 位作者 Mourad Elloumi Muhammad Azhar Mushtaq Ahlem Fatnassi Mohd Fazil Anas Bilal Abdulbasit A.Darem 《Computer Modeling in Engineering & Sciences》 2026年第1期118-155,共38页
Network-on-Chip(NoC)systems are progressively deployed in connecting massively parallel megacore systems in the new computing architecture.As a result,application mapping has become an important aspect of performance ... Network-on-Chip(NoC)systems are progressively deployed in connecting massively parallel megacore systems in the new computing architecture.As a result,application mapping has become an important aspect of performance and scalability,as current trends require the distribution of computation across network nodes/points.In this paper,we survey a large number of mapping and scheduling techniques designed for NoC architectures.This time,we concentrated on 3D systems.We take a systematic literature review approach to analyze existing methods across static,dynamic,hybrid,and machine-learning-based approaches,alongside preliminary AI-based dynamic models in recent works.We classify them into several main aspects covering power-aware mapping,fault tolerance,load-balancing,and adaptive for dynamic workloads.Also,we assess the efficacy of each method against performance parameters,such as latency,throughput,response time,and error rate.Key challenges,including energy efficiency,real-time adaptability,and reinforcement learning integration,are highlighted as well.To the best of our knowledge,this is one of the recent reviews that identifies both traditional and AI-based algorithms for mapping over a modern NoC,and opens research challenges.Finally,we provide directions for future work toward improved adaptability and scalability via lightweight learned models and hierarchical mapping frameworks. 展开更多
关键词 Application mapping mapping techniques NETWORK-ON-CHIP system on chip optimisation
在线阅读 下载PDF
Impact of Data Processing Techniques on AI Models for Attack-Based Imbalanced and Encrypted Traffic within IoT Environments
12
作者 Yeasul Kim Chaeeun Won Hwankuk Kim 《Computers, Materials & Continua》 2026年第1期247-274,共28页
With the increasing emphasis on personal information protection,encryption through security protocols has emerged as a critical requirement in data transmission and reception processes.Nevertheless,IoT ecosystems comp... With the increasing emphasis on personal information protection,encryption through security protocols has emerged as a critical requirement in data transmission and reception processes.Nevertheless,IoT ecosystems comprise heterogeneous networks where outdated systems coexist with the latest devices,spanning a range of devices from non-encrypted ones to fully encrypted ones.Given the limited visibility into payloads in this context,this study investigates AI-based attack detection methods that leverage encrypted traffic metadata,eliminating the need for decryption and minimizing system performance degradation—especially in light of these heterogeneous devices.Using the UNSW-NB15 and CICIoT-2023 dataset,encrypted and unencrypted traffic were categorized according to security protocol,and AI-based intrusion detection experiments were conducted for each traffic type based on metadata.To mitigate the problem of class imbalance,eight different data sampling techniques were applied.The effectiveness of these sampling techniques was then comparatively analyzed using two ensemble models and three Deep Learning(DL)models from various perspectives.The experimental results confirmed that metadata-based attack detection is feasible using only encrypted traffic.In the UNSW-NB15 dataset,the f1-score of encrypted traffic was approximately 0.98,which is 4.3%higher than that of unencrypted traffic(approximately 0.94).In addition,analysis of the encrypted traffic in the CICIoT-2023 dataset using the same method showed a significantly lower f1-score of roughly 0.43,indicating that the quality of the dataset and the preprocessing approach have a substantial impact on detection performance.Furthermore,when data sampling techniques were applied to encrypted traffic,the recall in the UNSWNB15(Encrypted)dataset improved by up to 23.0%,and in the CICIoT-2023(Encrypted)dataset by 20.26%,showing a similar level of improvement.Notably,in CICIoT-2023,f1-score and Receiver Operation Characteristic-Area Under the Curve(ROC-AUC)increased by 59.0%and 55.94%,respectively.These results suggest that data sampling can have a positive effect even in encrypted environments.However,the extent of the improvement may vary depending on data quality,model architecture,and sampling strategy. 展开更多
关键词 Encrypted traffic attack detection data sampling technique AI-based detection IoT environment
在线阅读 下载PDF
Prioritized Na^(+)Adsorption-Driven Cationic Electrostatic Repulsion Enables Highly Reversible Zinc Anodes at Low Temperatures
13
作者 Guanchong Mao Pan Xu +4 位作者 Xin Liu Xingyu Zhao Zexiang Shen Dongliang Chao Minghua Chen 《Nano-Micro Letters》 2026年第2期306-319,共14页
Aqueous zinc metal batteries(AZMBs)are promising candidates for renewable energy storage,yet their practical deployment in subzero environments remains challenging due to electrolyte freezing and dendritic growth.Alth... Aqueous zinc metal batteries(AZMBs)are promising candidates for renewable energy storage,yet their practical deployment in subzero environments remains challenging due to electrolyte freezing and dendritic growth.Although organic additives can enhance the antifreeze properties of electrolytes,their weak polarity diminishes ionic conductivity,and their flammability poses safety concerns,undermining the inherent advantages of aqueous systems.Herein,we present a cost-effective and highly stable Na_(2)SO_(4)additive introduced into a Zn(ClO_(4))2-based electrolyte to create an organic-free antifreeze electrolyte.Through Raman spectroscopy,in situ optical microscopy,densityfunctional theory computations,and molecular dynamics simulations,we demonstrate that Na+ions improve low-temperature electrolyte performance and mitigate dendrite formation by regulating uniform Zn^(2+)deposition through preferential adsorption and electrostatic interactions.As a result,the Zn||Zn cells using this electrolyte achieve a remarkable cycling life of 360 h at-40℃ with 61% depth of discharge,and the Zn||PANI cells retained an ultrahigh capacity retention of 91%even after 8000 charge/discharge cycles at-40℃.This work proposes a cost-effective and practical approach for enhancing the long-term operational stability of AZMBs in low-temperature environments. 展开更多
关键词 Low-temperature resistant Organic-free additive Aqueous batteries high stability
在线阅读 下载PDF
Highly Conductive and High-tensile Methacrylated Hyaluronic Acid Hydrogels for Strain Sensing Applications
14
作者 Meng Zhang Xu-Dong Yu 《Chinese Journal of Polymer Science》 2026年第1期127-139,I0012,共14页
Owing to their good biocompatibility,polysaccharide hydrogels have broad application prospects in the field of flexible strain sensors.However,there are still significant challenges in the preparation of polysaccharid... Owing to their good biocompatibility,polysaccharide hydrogels have broad application prospects in the field of flexible strain sensors.However,there are still significant challenges in the preparation of polysaccharide hydrogels with good mechanical properties.MCA-Li Cl hydrogels were prepared by introducing methacrylated hyaluronic acid(Me HA)into the polymer network in the presence of acrylic acid(AA),acryloyloxyethyltrimethyl ammonium chloride(CATAC),and metal ions.The polymer network not only has a chemically cross-linked network and a tough network structure,but also benefits from a variety of supramolecular interactions,such as hydrogen bonding and coordination covalent bonding,resulting in excellent mechanical properties,with an elongation at break of 1390%,a tensile strength of up to 1200 k Pa,a toughness of 9.4546 MJ/m^(3),and adhesive properties towards various substrates.At the same time,the hydrogel has a high conductivity(5.33 mS/cm)and high strain-sensing sensitivity(Gauge factor=2.55).The flexible strain sensor assembled from the prepared MCA-Li Cl hydrogel can be used to detect human movements,from micro-expressions(smiles,swallowing)to pulse signals and other physiological activities,as well as large-scale joint movements(wrists,elbows,knees,fingers,etc.),realizing the real-time monitoring of full-scale human movements.The prepared hydrogels have potential applications in wearable devices,electronic skin,and strain-sensor components. 展开更多
关键词 Hyaluronic acid high conductivity Flexible strain sensor
原文传递
First-Principles Study on the Mechanical and Thermodynamic Properties of (NbZrHfTi)C High-Entropy Ceramics
15
作者 Yonggang Tong Kai Yang +5 位作者 Pengfei Li Yongle Hu Xiubing Liang Jian Liu Yejun Li Jingzhong Fang 《Computers, Materials & Continua》 2026年第1期353-367,共15页
(NbZrHfTi)C high-entropy ceramics,as an emerging class of ultra-high-temperature materials,have garnered significant interest due to their unique multi-principal-element crystal structure and exceptional hightemperatu... (NbZrHfTi)C high-entropy ceramics,as an emerging class of ultra-high-temperature materials,have garnered significant interest due to their unique multi-principal-element crystal structure and exceptional hightemperature properties.This study systematically investigates the mechanical properties of(NbZrHfTi)C high-entropy ceramics by employing first-principles density functional theory,combined with the Debye-Grüneisen model,to explore the variations in their thermophysical properties with temperature(0–2000 K)and pressure(0–30 GPa).Thermodynamically,the calculated mixing enthalpy and Gibbs free energy confirm the feasibility of forming a stable single-phase solid solution in(NbZrHfTi)C.The calculated results of the elastic stiffness constant indicate that the material meets the mechanical stability criteria of the cubic crystal system,further confirming the structural stability.Through evaluation of key mechanical parameters—bulk modulus,shear modulus,Young’s modulus,and Poisson’s ratio—we provide comprehensive insight into the macro-mechanical behaviour of the material and its correlation with the underlying microstructure.Notably,compared to traditional binary carbides and their average properties,(NbZrHfTi)C exhibits higher Vickers hardness(Approximately 28.5 GPa)and fracture toughness(Approximately 3.4 MPa⋅m^(1/2)),which can be primarily attributed to the lattice distortion and solid-solution strengthening mechanism.The study also utilizes the quasi-harmonic approximation method to predict the material’s thermophysical properties,including Debye temperature(initial value around 563 K),thermal expansion coefficient(approximately 8.9×10^(−6) K−1 at 2000 K),and other key parameters such as heat capacity at constant volume.The results show that within the studied pressure and temperature ranges,(NbZrHfTi)C consistently maintains a stable phase structure and good thermomechanical properties.The thermal expansion coefficient increasing with temperature,while heat capacity approaches the Dulong-Petit limit at elevated temperatures.These findings underscore the potential of(NbZrHfTi)C applications in ultra-high temperature thermal protection systems,cutting tool coatings,and nuclear structural materials. 展开更多
关键词 high entropy ceramics mechanical properties electronic properties thermodynamic properties
在线阅读 下载PDF
Characterization of the susceptibility of ore particles to breakdown in high voltage pulse breakage and the influencing factors
16
作者 Rui Sun Yang Hong +5 位作者 Daqian Wang Liang Si Jianguo Yang Wei Huang Liefeng Huang Weiran Zuo 《International Journal of Mining Science and Technology》 2026年第1期113-124,共12页
The susceptibility of ore particles to electrical breakdown plays a critical role for high voltage pulse(HVP)breakage,yet its quantitative characterization still lacks deep understanding.Two indicators,namely breakdow... The susceptibility of ore particles to electrical breakdown plays a critical role for high voltage pulse(HVP)breakage,yet its quantitative characterization still lacks deep understanding.Two indicators,namely breakdown delay time(T_(d))and breakdown strength(E_(b))were compared,based on analysis on the two breakdown modes namely wavefront mode and post-wave mode.It was found that T_(d) is more suitable to characterize the susceptibility of ore particles to electrical breakdown in HVP breakage than E_(b).A probabilistic model based on the Weibull distribution is developed to describe the relation of breakdown probability to T_(d).Regression analyses were conducted to investigate how operating parameters and particle properties influence Td and size reduction degree of ore particles in HVP breakage.The regressed models demonstrate potential capability to predict metallic minerals content and HVP breakage degree based on operating parameters and particle properties. 展开更多
关键词 Electrical breakdown high voltage pulse breakage SUSCEPTIBILITY Breakdown delay time
在线阅读 下载PDF
Research Advances in Modern Analytical Techniques for Quality Control and Clinical Application of Ganmai Dazao Decoction
17
作者 Zihan Zhu 《Journal of Clinical and Nursing Research》 2026年第1期338-344,共7页
Ganmai Dazao Decoction,originating from“Jin Gui Yao Lue”(Synopsis of the Golden Chamber),is a classical prescription for treating visceral agitation.Composed of three medicinal and edible substances-licorice(Gancao)... Ganmai Dazao Decoction,originating from“Jin Gui Yao Lue”(Synopsis of the Golden Chamber),is a classical prescription for treating visceral agitation.Composed of three medicinal and edible substances-licorice(Gancao),wheat(Xiaomai),and jujube(Dazao),it functions to nourish the heart and calm the mind,harmonize the middle burner and regulate Qi,and alleviate urgency and restlessness.As its clinical application has expanded from traditional emotional disorders to neurological,endocrine,and various psychosomatic diseases,establishing a scientifically precise quality control system and deeply elucidating its pharmacodynamic material basis and mechanism of action have become critical tasks.Modern analytical methods,typified by chromatography,spectroscopy,and their hyphenated techniques,with their high sensitivity,high resolution,and powerful substance characterization capabilities,have become the core driving force for standardizing the quality control and modernizing the clinical application research of this formula.This paper systematically reviews the progress of the aforementioned analytical techniques and chemometrics in interpreting the chemical composition,establishing fingerprint profiles,controlling process quality,and researching the pharmacodynamic material basis of Ganmai Dazao Decoction.Furthermore,it discusses integrated approaches combining analytical techniques with pharmacology and clinical medicine to reveal mechanisms of action and explore therapeutic biomarkers.Finally,it provides an outlook on future directions and challenges,including technological integration and innovation,standardization of whole-process quality control systems,and evidence-based research aimed at internationalization. 展开更多
关键词 Ganmai Dazao Decoction Quality control Modern analytical techniques FINGERPRINT Pharmacodynamic material basis Clinical application
暂未订购
Synaptic pruning mechanisms and application of emerging imaging techniques in neurological disorders
18
作者 Yakang Xing Yi Mo +1 位作者 Qihui Chen Xiao Li 《Neural Regeneration Research》 2026年第5期1698-1714,共17页
Synaptic pruning is a crucial process in synaptic refinement,eliminating unstable synaptic connections in neural circuits.This process is triggered and regulated primarily by spontaneous neural activity and experience... Synaptic pruning is a crucial process in synaptic refinement,eliminating unstable synaptic connections in neural circuits.This process is triggered and regulated primarily by spontaneous neural activity and experience-dependent mechanisms.The pruning process involves multiple molecular signals and a series of regulatory activities governing the“eat me”and“don't eat me”states.Under physiological conditions,the interaction between glial cells and neurons results in the clearance of unnecessary synapses,maintaining normal neural circuit functionality via synaptic pruning.Alterations in genetic and environmental factors can lead to imbalanced synaptic pruning,thus promoting the occurrence and development of autism spectrum disorder,schizophrenia,Alzheimer's disease,and other neurological disorders.In this review,we investigated the molecular mechanisms responsible for synaptic pruning during neural development.We focus on how synaptic pruning can regulate neural circuits and its association with neurological disorders.Furthermore,we discuss the application of emerging optical and imaging technologies to observe synaptic structure and function,as well as their potential for clinical translation.Our aim was to enhance our understanding of synaptic pruning during neural development,including the molecular basis underlying the regulation of synaptic function and the dynamic changes in synaptic density,and to investigate the potential role of these mechanisms in the pathophysiology of neurological diseases,thus providing a theoretical foundation for the treatment of neurological disorders. 展开更多
关键词 CHEMOKINE COMPLEMENT experience-dependent driven synaptic pruning imaging techniques NEUROGLIA signaling pathways synapse elimination synaptic pruning
暂未订购
A sustainable and high value-added strategy under lignite and waste silicon powder to construct SiC nanowires for electromagnetic wave absorption
19
作者 Wenhao Wang Xiaolin Lan +6 位作者 Haoquan Hao Jingxiang Liu Yong Shuai Qinghe Jing Shouqing Yan Jie Guo Zhijiang Wang 《International Journal of Minerals,Metallurgy and Materials》 2026年第1期347-356,共10页
The electromagnetic wave absorption of silicon carbide nanowires is improved by their uniform and diverse cross-structures.This study introduces a sustainable and high value-added method for synthesizing silicon carbi... The electromagnetic wave absorption of silicon carbide nanowires is improved by their uniform and diverse cross-structures.This study introduces a sustainable and high value-added method for synthesizing silicon carbide nanowires using lignite and waste silicon powder as raw materials through carbothermal reduction.The staggered structure of nanowires promotes the creation of interfacial polarization,impedance matching,and multiple loss mechanisms,leading to enhanced electromagnetic absorption performance.The silicon carbide nanowires demonstrate outstanding electromagnetic absorption capabilities with the minimum reflection loss of-48.09 d B at10.08 GHz and an effective absorption bandwidth(the reflection loss less than-10 d B)ranging from 8.54 to 16.68 GHz with a thickness of 2.17 mm.This research presents an innovative approach for utilizing solid waste in an environmentally friendly manner to produce broadband silicon carbide composite absorbers. 展开更多
关键词 LIGNITE waste silicon powder SiC nanowires electromagnetic wave absorption high value-added
在线阅读 下载PDF
Lifestyle behaviors,serum metabolites and high myopia:Mendelian randomization and mediation analysis
20
作者 Nian-En Liu Xiao-Tong Xu Xiao-Bing Yu 《International Journal of Ophthalmology(English edition)》 2026年第1期140-148,共9页
AIM:To explore the causal relationship between several possible behavioral factors and high myopia(HM)using multivariable Mendelian randomization(MVMR)approach and to find the mediators among them with mediation analy... AIM:To explore the causal relationship between several possible behavioral factors and high myopia(HM)using multivariable Mendelian randomization(MVMR)approach and to find the mediators among them with mediation analysis.METHODS:The causal effects of several behavioral factors,including screen time,education time,time spent outdoors,and physical activity,on the risk of HM using univariable Mendelian randomization(MR)and MVMR analyses were first assessed.Genome-wide association study summary statistics of serum metabolites were also used in mediation analysis to determine the extent to which serum metabolites mediate the effects of behavioral factors on HM.RESULTS:MR analyses indicated that both increased time spent outdoors and a higher frequency of moderate physical activity significantly reduced the risk of HM.Further MVMR analysis confirmed that moderate physical activity independently contributed to a lower risk of HM.Additionally,MR analyses identified 13 serum metabolites significantly associated with HM,of which 12 were lipids and one was an amino acid derivative.Mediation analysis revealed that six lipid metabolites mediated the protective effects of moderate physical activity on HM,with the highest mediation proportion observed for 1-(1-enyl-palmitoyl)-GPC(p-16:0;30.83%).CONCLUSION:This study suggests that in addition to outdoor time,moderate physical activity habits may have an independent protective effect against HM and pointed to lipid metabolites as priority targets for the prevention due to low physical activity.These results emphasize the importance of physical activity and metabolic health in HM and underscore the need for further study of these complex associations. 展开更多
关键词 high myopia physical activity serum metabolites multivariable Mendelian randomization mediation analysis
原文传递
上一页 1 2 250 下一页 到第
使用帮助 返回顶部