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Feeling the Fragrance--Blending tradition with modern elements,young entrepreneurs revive tea industry and culture in Songyang
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作者 YANG SHUANGSHUANG 《ChinAfrica》 2026年第1期54-55,共2页
On the stone-paved lanes of Songyang County that date back to ancient times,morning mist lingered as a faint fragrance of tea wafted from a century-old house.Inside,Yang Junjie,a tea maker born in the 1980s,worked def... On the stone-paved lanes of Songyang County that date back to ancient times,morning mist lingered as a faint fragrance of tea wafted from a century-old house.Inside,Yang Junjie,a tea maker born in the 1980s,worked deftly at the stove,his hands moving swiftly over the scorching iron wok as tender green tea leaves dance between his fingers. 展开更多
关键词 tea scorching iron wok FRAGRANCE tea leaves modern elements TRADITION Songyang tea making
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Tapping Chinese Tea Market Through CAEXPO Mall
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《China Report ASEAN》 2025年第9期55-55,共1页
Myanmar has a long teagrowing tradition,with 800,000 acres of plantations in both northern and southern Shan State.Its unspoiled environment offers a unique natural advantage,providing top-quality tea leaves for makin... Myanmar has a long teagrowing tradition,with 800,000 acres of plantations in both northern and southern Shan State.Its unspoiled environment offers a unique natural advantage,providing top-quality tea leaves for making premium milk tea.Yoke The’Myanmar Milk Tea,a signature product from Taw Win Kanbawza Mountain Company(Myanmar),is a flagship of the country’s tea culture and reflects its distinctive flavors and local charm. 展开更多
关键词 tea plantations milk teayoke Taw Win Kanbawza mountain company Myanmar milk tea milk teaa premium milk tea Chinese tea market Myanmar
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A Review of the Relationship between Tea Drinking and Breast Cancer
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作者 Jingjing Yu Suriyakala Perumal Chandran +1 位作者 Farra Aidah Jumuddin Nurul Azmir Amir Hashim 《Proceedings of Anticancer Research》 2025年第2期1-19,共19页
The global incidence of breast cancer remains high and is increasing annually in some regions.Despite the variety of current treatments for breast cancer,the preventive and therapeutic effects are still limited due to... The global incidence of breast cancer remains high and is increasing annually in some regions.Despite the variety of current treatments for breast cancer,the preventive and therapeutic effects are still limited due to the highly heterogeneous nature and complex biological mechanisms of breast cancer.In recent years,tea consumption has emerged as a research focus due to its possible anti-cancer properties.Numerous preclinical studies have demonstrated that regular tea intake could potentially curb the progression of breast cancer by influencing various biological mechanisms,including signaling pathways,cell cycle regulation,and immune system responses,among others.Nonetheless,the findings from epidemiological studies show considerable variability,and the connection between tea drinking and both the risk and outlook for breast cancer is shaped by numerous elements.These include the specific type of tea consumed,the quantity consumed,individual genetic variations,and environmental influences.This article summarizes the current research findings and delves into the connection between tea consumption and the risk as well as the prognosis of breast cancer among different regional populations.Meanwhile,it expounds on the potential molecular biological mechanisms behind it.The aim is to offer a theoretical foundation for the personalized prevention and treatment of breast cancer. 展开更多
关键词 tea drinking Breast cancer RISK PROGNOSIS Green tea Black tea
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From Leaf to Cloud Fuding is bringing new life to centuries-old tea cultivation with digital approaches
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作者 Gao Yuan 《China Report ASEAN》 2025年第10期35-37,共3页
In May 2025,the Fuding White Tea Culture System in southeast China’s Fujian Province was officially recognized by the UN Food and Agriculture Organization(FAO)as a Globally Important Agricultural Heritage System(GIAH... In May 2025,the Fuding White Tea Culture System in southeast China’s Fujian Province was officially recognized by the UN Food and Agriculture Organization(FAO)as a Globally Important Agricultural Heritage System(GIAHS).It mainly includes national-level superior varieties-Fuding Dabai Tea,Fuding Dahao Tea,and Fuding Cai Tea(group variety)which retains tradition and uses tea seeds for sexual reproduction-providing abundant germplasm resources for cultivating new tea varieties. 展开更多
关键词 tea seeds germplasm resources globally important agricultural heritage system sexual reproduction globally important agricultural heritage system giahs digital approaches tea cultivation Fuding White tea
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Metok:Land of Fruit and Tea
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作者 Bian Zijie Wang Xi Chen Weiguo 《China's Tibet》 2025年第4期4-9,共6页
As the warm breeze sweeps over the peaks of the Himalayas,spring air fills the vast Qinghai-Xizang Plateau.Residents of Metok County,Nyingchi City,Xizang,are welcoming the"harvest season"busy picking tender ... As the warm breeze sweeps over the peaks of the Himalayas,spring air fills the vast Qinghai-Xizang Plateau.Residents of Metok County,Nyingchi City,Xizang,are welcoming the"harvest season"busy picking tender tea leaves and loquats. 展开更多
关键词 PEAKS tea Qinghai Xizang plateau Nyingchi City tea leaves HARVEST Metok County LOQUAT
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From Mines to Tea Mountains:One Village’s Twenty-Year Path of Green Transformation
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作者 YANG SHUANGSHUANG 《China Today》 2025年第10期68-70,共3页
Once a mining village,Jingshan in Hangzhou has reinvented itself over the past 20 years as a thriving model of green transformation.STROLLING through a village named Jingshan located in Hangzhou City,east China’s Zhe... Once a mining village,Jingshan in Hangzhou has reinvented itself over the past 20 years as a thriving model of green transformation.STROLLING through a village named Jingshan located in Hangzhou City,east China’s Zhejiang Province,one will notice the image of a“little tea farmer”wearing a bamboo hat and carrying a tea basket in many places. 展开更多
关键词 mining village green transformationstrolling green transformation bamboo hat village development tea cultivation tea basket environmental sustainability
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The Ancient Tea-Horse Road:A Testamentto Interaction and Inteyration between Ethnic Groups
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作者 Zhou Anyong Huang Wenjuan(Translated) 《China's Tibet》 2025年第3期34-39,共6页
Along the ancient Tea-Horse Road of thousands of miles between Sichuan and Xizang in Southwest China lies a centuries old courtyard.Commonly called the"Jiang Family Compound"or"Yu Xing Tea Store",t... Along the ancient Tea-Horse Road of thousands of miles between Sichuan and Xizang in Southwest China lies a centuries old courtyard.Commonly called the"Jiang Family Compound"or"Yu Xing Tea Store",this architecture situated in the old downtown area of Yingjing County in Ya'an City,Sichuan Province,was once the residence of the local tea merchants-the Jiang family. 展开更多
关键词 Yu Xing tea store ancient tea horse road Sichuan Xizang Sichuan province Jiang family compound Yingjing county ethnic groups Yaan city
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Development of Lemon-Flavored Solid Instant Tea
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作者 Yan WANG Yikang FENG Lei PENG 《Medicinal Plant》 2025年第1期30-34,共5页
[Objectives]To investigate the optimal preparation process for lemon-flavored solid instant tea.[Methods]The formulation process was optimized through a single-factor combined orthogonal test,utilizing large-leaf Pu&#... [Objectives]To investigate the optimal preparation process for lemon-flavored solid instant tea.[Methods]The formulation process was optimized through a single-factor combined orthogonal test,utilizing large-leaf Pu'er tea as the primary raw material and perfume lemon as the auxiliary ingredient.Sensory scores and the effectiveness of the spray drying process served as the key indicators for this investigation.[Results]The optimal formulation for lemon-flavored solid instant tea was established as follows:15 g of Pu'er tea,25 g of perfume lemon,a solid-liquid ratio of 1:20(g/mL),an extraction temperature of 90℃,an extraction duration of 30 min,and air inlet and outlet temperatures of 200℃and 80℃,respectively.This formulation produced the most favorable flavor profile for the perfume lemon-flavored solid instant tea,which was characterized by a stable texture and a sensory evaluation score of 91.97 points.[Conclusions]This study has the potential to enhance the development and utilization of large-leaf Pu'er tea and perfume lemon resources. 展开更多
关键词 Large-leaf Pu'er tea Instant tea Spray drying Perfume lemon
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Impact of Climate Change on the First Plucking Date and Quality of Huiming Tea in Jingning
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作者 Dalin WANG Dan SONG +2 位作者 Ming LUO Siwei ZHENG Keru FANG 《Meteorological and Environmental Research》 2025年第4期43-47,50,共6页
Based on the observation data of daily average temperature,daily rainfall and sunshine duration from 2005 to 2024 from the national basic meteorological station and regional meteorological station in Jingning,as well ... Based on the observation data of daily average temperature,daily rainfall and sunshine duration from 2005 to 2024 from the national basic meteorological station and regional meteorological station in Jingning,as well as the data of tea yield and growth period,the first picking date and quality of Huiming tea in Jingning were evaluated by the analysis of physical and chemical indicators and climate quality index of Huiming tea.The results show that in the past two decades,the first picking date of Huiming tea showed a significant advancing trend.Climate warming led to an increase in≥0℃active accumulated temperature,thus advancing the first picking date.The climate quality index of tea was"very excellent"in most years,and the physical and chemical indicators were at the special grade.Tea yield was significantly correlated with multiple meteorological factors,especially closely related to sunshine duration in early February and≥5℃active accumulated temperature from February to April. 展开更多
关键词 Huiming tea Climate change tea quality
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The Healthcare Efficacy Research Progress on Tea and Herbal Tea
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作者 Aiketaguli Anwaierjiang Mayinuer Abuduwake 《Journal of Clinical and Nursing Research》 2025年第7期215-221,共7页
Tea and herbal tea,as a combination of traditional medicine and modern health concepts,has been favored by more and more people due to its long-term efficacy and mechanism of action.Based on the introduction of the ba... Tea and herbal tea,as a combination of traditional medicine and modern health concepts,has been favored by more and more people due to its long-term efficacy and mechanism of action.Based on the introduction of the basic concept and development process of tea and medicinal tea,this article focuses on their health care functions and mechanisms,and analyzes the application effects of tea and medicinal tea in different diseases,to provide scientific basis and useful reference for their application and promotion in practice. 展开更多
关键词 tea Medicinal tea Health benefits Online publication:August 1 2025
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Research on Pragmatic Relevance and Translation of Tea Culture Terminology from the Perspective of Digitalized Teaching
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作者 Jieying Hu 《Journal of Contemporary Educational Research》 2025年第9期115-122,共8页
This paper focuses on the teaching of tea culture terminology translation against the backdrop of digital transformation in education.Based on the theory of pragmatic relevance,the research emphasizes shifting the foc... This paper focuses on the teaching of tea culture terminology translation against the backdrop of digital transformation in education.Based on the theory of pragmatic relevance,the research emphasizes shifting the focus of translation from static linguistic equivalence to more dynamic communicative effectiveness.This paper advocates the flexible application of various strategies.These include literal translation,free translation,transliteration with annotation,and adaptive translation based on the target audience’s cognitive context.The paper innovatively proposes digitally-enabled teaching implementation paths,including constructing modular online courses,building intelligent terminology case databases,conducting cloud-based workshops on translation,and implementing industry-academia collaborative project practices.These aim to reshape the teaching process utilizing digital technology,effectively cultivating higher vocational students’cultural communication abilities and practical translation skills,thereby providing high-quality language service talent support for the internationalization of Chinese tea culture. 展开更多
关键词 tea culture terminology Pragmatic relevance Translation strategies Digitalized teaching Business English
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English Retranslations of The Classic on Tea From the Perspective of Cultural Awareness
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作者 WANG Chengping JIA Xiaoqing 《Psychology Research》 2025年第4期165-170,共6页
The paper analyzes the English retranslation of The Classic on Tea from the perspective of cultural awareness and finds some misinterpretations and omissions of Chinese culture appeared in the translations of foreign ... The paper analyzes the English retranslation of The Classic on Tea from the perspective of cultural awareness and finds some misinterpretations and omissions of Chinese culture appeared in the translations of foreign scholars.Domestic translators have a deeper understanding of Chinese culture and their retranslations embody the increasing cultural awareness of the source language culture,mainly in seeking conceptual equivalence rather than lexical equivalence,choosing the most suitable translation according to the textual and cultural context,and focusing on cultural facsimile and readers’awareness.This study will help better spread the Chinese tea culture and help Chinese culture go global. 展开更多
关键词 English retranslation of The Classic on tea the perspective of cultural awareness Chinese tea culture
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Highly efficient discovery of the covalent M^(pro)inhibitors from crude Pu-erh tea by integrating biochemical and chemoproteomic approaches
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作者 Guanghao Zhu Yani Zhang +9 位作者 Shenglan Qi Jianrong Xu Yuan Xiong Zhaoqin Zhang Xixiang Chen Yuanyuan Xie Xiaoqing Guan Weidong Zhang Wei Liu Guangbo Ge 《Food Science and Human Wellness》 2025年第5期1864-1873,共10页
The main proteases(M^(pro)s)are hydrolases playing essential roles in the replication ofβ-coronaviruses including SARS-CoV-2.Herein,a highly efficient strategy was developed for discovering the M^(pro)inactivators fr... The main proteases(M^(pro)s)are hydrolases playing essential roles in the replication ofβ-coronaviruses including SARS-CoV-2.Herein,a highly efficient strategy was developed for discovering the M^(pro)inactivators from crude plant extract integrating target-based biochemical assay and chemoproteomic approaches.Firstly,Pu-erh tea was found to potently suppress SARS-CoV-2 M^(pro)in a time-dependent manner.Next,global chemical analysis coupling with peptide-modification profiling were used to identify the cysteine-modified constituents in Pu-erh tea.The results suggested that seven constituents in Pu-erh tea could modify SARSCoV-2 M^(pro),which turned out that epigallocatechin,gallocatechin and gallic acid were the most efficacious M^(pro)inactivators.Further investigations demonstrated that epigallocatechin and gallocatechin could inactivate S ARS-CoV-2 M^(pro)via blocking the formation of the homodimers.Collectively,this work proposed a novel and practical strategy for highly efficient discovery of time-dependent inhibitors of SARS-CoV-2 M^(pro)from plant extracts,while 3 constituents in Pu-erh tea have emerged as robust SARS-CoV-2 M^(pro)inactivators. 展开更多
关键词 Main proteases(M^(pro)) Plant extract Pu-erh tea Global chemical analysis Cysteine-modification profiling
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Status quo and Countermeasures of Tea Export Trade of China 被引量:4
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作者 桂燕玲 《Agricultural Science & Technology》 CAS 2015年第7期1527-1530,1551,共5页
The research analyzed status quo of Chinese tea export, including export scale, exporting countries and regions, product structure, explored factors affecting tea export, and detailed international trade development o... The research analyzed status quo of Chinese tea export, including export scale, exporting countries and regions, product structure, explored factors affecting tea export, and detailed international trade development of Chinese teas. On basis of global politics and economic situations, the research proposed new thoughts and of global trades of Chinese teas with application of the Belt and Road Initiative strategy. 展开更多
关键词 tea Chinese tea export International tea trade Status quo
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Inheritance,Innovation and High-quality Development of Tea Industry in Xianning City,Hubei Province 被引量:6
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作者 Li GAO Zhiguo SUN +3 位作者 Yueqiu HE Deying ZHANG Jiandong LAI Zhen CHEN 《Asian Agricultural Research》 2022年第8期15-20,27,共7页
Xianning City is a main tea producing area in Hubei Province,the capital of"border-selling tea"in China,and an important starting point for the Ten-Thousand-Mile Tea Road across the Eurasian continent.This p... Xianning City is a main tea producing area in Hubei Province,the capital of"border-selling tea"in China,and an important starting point for the Ten-Thousand-Mile Tea Road across the Eurasian continent.This paper studies the tea industry in Xianning from the aspects of top 100 counties of tea industry,important agricultural cultural heritage,famous Chinese historical and cultural villages,China’s time-honored brands,major brands,and designated production enterprises of border-selling tea.Besides,it introduces intellectual property resources of the tea industry from traditional knowledge,biological genetic resources,new plant varieties,patents,geographical indications,trademarks,etc.Then,it analyzes major problems in the inheritance,innovation and high-quality development of Xianning tea,especially the border-selling tea.Finally,it comes up with constructive recommendations of starting the cultural inheritance and development project and upgrade project of the tea industry to build the capital of China’s border-selling tea. 展开更多
关键词 Capital of border-selling tea Ten-Thousand-Mile tea Road tea industry Inheritance of tea culture Innovation driving High-quality development
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Insight into the sorption and desorption pattern of pyrrolizidine alkaloids and their N-oxides in acidic tea(Camellia sinensis)plantation soils 被引量:2
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作者 Yuting Lu Haolei Han +5 位作者 Yuexing Yi Yunfeng Chai ChenWang Xiangchun Zhang Xiangde Yang Hongping Chen 《Journal of Environmental Sciences》 2025年第2期350-363,共14页
Pyrrolizidine alkaloids(PAs)and their N-oxides(PANOs)are phytotoxins produced by various plant species and have been emerged as environmental pollutants.The sorption/desorption behaviors of PAs/PANOs in soil are cruci... Pyrrolizidine alkaloids(PAs)and their N-oxides(PANOs)are phytotoxins produced by various plant species and have been emerged as environmental pollutants.The sorption/desorption behaviors of PAs/PANOs in soil are crucial due to the horizontal transfer of these natural products from PA-producing plants to soil and subsequently absorbed by plant roots.This study firstly investigated the sorption/desorption behaviors of PAs/PANOs in tea plantation soils with distinct characteristics.Sorption amounts for seneciphylline(Sp)and seneciphylline-N-oxide(SpNO)in three acidic soils ranged from 2.9 to 5.9μg/g and 1.7 to 2.8μg/g,respectively.Desorption percentages for Sp and SpNO were from 22.2%to 30.5%and 36.1%to 43.9%.In the mixed PAs/PANOs systems,stronger sorption of PAs over PANOs was occurred in tested soils.Additionally,the Freundlich models more precisely described the sorption/desorption isotherms.Cation exchange capacity,sand content and total nitrogen were identified as major influencing factors by linear regression models.Overall,the soils exhibiting higher sorption capacities for compounds with greater hydrophobicity.PANOs were more likely to migrate within soils and be absorbed by tea plants.It contributes to the understanding of environmental fate of PAs/PANOs in tea plantations and provides basic data and clues for the development of PAs/PANOs reduction technology. 展开更多
关键词 Pyrrolizidine alkaloids Sorption-desorption behavior tea plantation system Acidic soil Linear regression model
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Transcutaneous electrical acupoint stimulation(TEAS):Applications and challenges 被引量:2
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作者 Wen-lai ZHOU Jing LI +4 位作者 Xiao-ning SHEN Xia-tong HUA Jing XIE Yan-li ZHOU Lu ZHU 《World Journal of Acupuncture-Moxibustion》 2025年第1期10-16,共7页
Transcutaneous electrical acupoint stimulation(TEAS)is a kind of physical therapy that use electric cur-rent through the electrodes placed on the surface of acupoints to produce clinical effects in the human body,whic... Transcutaneous electrical acupoint stimulation(TEAS)is a kind of physical therapy that use electric cur-rent through the electrodes placed on the surface of acupoints to produce clinical effects in the human body,which is characterized by less adverse reaction and convenient operation.It has been widely used in the treatment of various diseases.This review introduces six major clinical applications of TEAS,named analgesia,regulation of gastrointestinal function,improvement of reproductive function,enhancement of cognitive function,promotion of limb function recovery and relief of fatigue.Besides,TEAS has been ap-plied to the treatment of other chronic diseases such as hypertension and diabetes,achieving satisfactory clinical effects.However,two crucial challenges are encountered in the development of TEAS.One is the lack of standardization in the selection of parameters such as waveform,frequency,intensity and stimula-tion duration.The other is the limitation on the flexibility in the acupoint selection.This review analyzes key issues that need to be addressed in the current clinical application of TEAS,such as the selection of parameters and acupoints,and this review provides a certain reference value for optimizing regimens of TEAS and promoting its development and application. 展开更多
关键词 Transcutaneous electrical acupoint stimulation(teaS) Clinical application Influence factors Parameter selection
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Effects of ultrasonic-assisted extraction on bioactive compounds,volatile flavors and antioxidant activities of vine tea water extracts
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作者 Xiao-Long Zhou Wei-Jin Jiang +2 位作者 Ji Yu Mao-Jun Yao Yun-Tong Li 《Traditional Medicine Research》 2025年第1期73-81,共9页
Background:Ampelopsis grossedentata,vine tea,which is the tea alternative beverages in China.In vine tea processing,a large amount of broken tea is produced,which has low commercial value.Methods:This study investigat... Background:Ampelopsis grossedentata,vine tea,which is the tea alternative beverages in China.In vine tea processing,a large amount of broken tea is produced,which has low commercial value.Methods:This study investigates the influence of different extraction methods(room temperature water extraction,boiling water extraction,ultrasonic-assisted room temperature water extraction,and ultrasonic-assisted boiling water extraction,referred to as room temperature water extraction(RE),boiling water extraction(BE),ultrasonic assistance at room temperature water extraction(URE),and ultrasonic assistance in boiling water extraction(UBE))on the yield,dihydromyricetin(DMY)content,free amino acid composition,volatile aroma components,and antioxidant properties of vine tea extracts.Results:A notable influence of extraction temperature on the yield of vine tea extracts(P<0.05),with BE yielding the highest at 43.13±0.26%,higher than that of RE(34.29±0.81%).Ultrasound-assisted extraction significantly increased the DMY content of the extracts(P<0.05),whereas DMY content in the RE extracts was 59.94±1.70%,that of URE reached 66.14±2.78%.Analysis revealed 17 amino acids,with L-serine and aspartic acid being the most abundant in the extracts,nevertheless ultrasound-assisted extraction reduced total free amino acid content.Gas chromatography-mass spectrometry analysis demonstrated an increase in the diversity and quantity of compounds in the vine tea water extracts obtained through ultrasonic-assisted extraction.Specifically,69 and 68 volatile compounds were found in URE and UBE extracts,which were higher than the number found in RE and BE extracts.In vitro,antioxidant activity assessments revealed varying antioxidant capacities among different extraction methods,with RE exhibiting the highest DPPH scavenging rate,URE leading in ABTS•+free radical scavenging,and BE demonstrating superior ferric ion reducing antioxidant activity.Conclusion:The findings suggest that extraction methods significantly influence the chemical composition and antioxidant properties of vine tea extracts.Ultrasonic-assisted extraction proved instrumental in elevating the DMY content in vine tea extracts,thereby enriching its flavor profile while maintaining its antioxidant properties. 展开更多
关键词 vine tea DIHYDROMYRICETIN ultrasonic-assisted extraction volatile aroma components
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RNA甲基转移酶NSUN2通过介导TEAD1 m5C甲基化修饰促进胃癌细胞的糖酵解作用
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作者 王春云 阳乐斌 唐芬芬 《华中科技大学学报(医学版)》 北大核心 2025年第6期812-820,883,共10页
目的 探讨NOP2/Sun RNA甲基转移酶2(NSUN2)通过介导TEA结构域转录因子1(TEAD1)5-甲基胞嘧啶(m5C)甲基化修饰对胃癌(gastric cancer, GC)细胞糖酵解的影响及其机制。方法 实时荧光定量PCR(qRT-PCR)检测人胃癌(GC)组织中NSUN2和TEAD1 mRN... 目的 探讨NOP2/Sun RNA甲基转移酶2(NSUN2)通过介导TEA结构域转录因子1(TEAD1)5-甲基胞嘧啶(m5C)甲基化修饰对胃癌(gastric cancer, GC)细胞糖酵解的影响及其机制。方法 实时荧光定量PCR(qRT-PCR)检测人胃癌(GC)组织中NSUN2和TEAD1 mRNA表达水平,Pearson相关分析两者相关性。qRT-PCR和蛋白质印迹法(Western blot)检测人正常胃黏膜上皮细胞GES-1及胃癌AGS、HGC-27、SNU-1和MKN-45等细胞系中NSUN2表达水平。将NSUN2干扰慢病毒(sh-NSUN2)及其阴性对照sh-NC、TEAD1过表达质粒(oe-TEAD1)及其阴性对照(Vector)分别或同时转染至HGC-27细胞中,CCK-8检测细胞增殖活性。葡萄糖摄取、乳酸含量以及三磷酸腺苷(ATP)检测试剂盒评估细胞糖酵解。Western blot检测细胞中糖酵解途径相关蛋白(HK2、LDHA、GLUT1)表达水平。qRT-PCR和Western blot检测细胞中TEAD1 mRNA和蛋白表达水平。RNA测序(RNA-seq)和RNA甲基化免疫共沉淀实验筛选NSUN2的5-甲基胞嘧啶(m5C)修饰靶点,同时采用斑点杂交和双荧光素酶报告基因实验验证其调控功能。结果 与癌旁组织比较,GC组织中NSUN2和TEAD1 mRNA表达水平均显著升高(均P<0.05),且两者呈正相关(r=0.3266,P<0.05)。与GES-1细胞系比较,胃癌细胞系(AGS、HGC-27、SNU-1和MKN-45)中NSUN2 mRNA和蛋白表达水平显著升高,其中在HGC-27细胞系中表达最高(均P<0.05)。沉默NSUN2可显著降低HGC-27细胞增殖活性和糖酵解,下调HK2、LDHA和GLUT1蛋白表达水平,同时细胞中TEAD1 mRNA和蛋白表达水平显著降低(均P<0.05)。TEAD1是NSUN2调控的潜在靶点,沉默NSUN2通过m5C修饰的方式降低TEAD1的表达(P<0.05)。然而,过表达TEAD1可明显逆转沉默NSUN2对HGC-27细胞增殖活性和糖酵解的抑制作用。结论 NSUN2通过m5C依赖性的方式增强TEAD1的表达进而促进GC细胞的糖酵解。 展开更多
关键词 NOP2/Sun RNA甲基转移酶2 tea结构域转录因子1 5-甲基胞嘧啶 甲基化 胃癌 糖酵解
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A Rare Sesquiterpene from Hawk Tea
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作者 Guo Dongyang Cong Jingxian +5 位作者 Zhang Maosheng Dong Minjiana Liang Guangxiang Sun Chengxin Wu Wenxi Xiao Shiji 《有机化学》 北大核心 2025年第9期3486-3489,共4页
A rare sesquiterpene of hawkteasesquioid A(1),featuring a novel 5/6/5 tricyclic system containing a 6,5-spiroketal motif,was isolated from the bark of Litsea coreana Lévl.var.lanuginosa(hawk tea).The structure of... A rare sesquiterpene of hawkteasesquioid A(1),featuring a novel 5/6/5 tricyclic system containing a 6,5-spiroketal motif,was isolated from the bark of Litsea coreana Lévl.var.lanuginosa(hawk tea).The structure of this compound was elucidated based on the high-resolution electrospray ionization mass spectrometry(HRESIMS),one-dimensional(1D)and two-dimensional(2D)nuclear magnetic resonance(NMR)spectroscopy,and single-crystal X-ray diffraction data.The cytotoxicity of this compound was assessed on the A549,HT-29,and SW1990 cell lines. 展开更多
关键词 hawk tea Litsea coreana LAURACEAE SESQUITERPENE
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