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Functional redundancy of three mitochondrial Mg^(2+)/Mn^(2+)dependent protein phosphatases(PPMs)in Toxoplasma gondii
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作者 Kaiyin SHENG Xueqiu CHEN +6 位作者 Yimin YANG Jie XIA Kaiyue SONG Chaoqun YAO Yi YANG Aifang DU Guangxu MA 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 2025年第4期405-408,共4页
Toxoplasma gondii is a single-celled parasite that infects nearly all warm-blooded animals,including humans(Montoya and Liesenfeld,2004).It occurs worldwide and can persist for a lifetime in mammals.Humans get infecte... Toxoplasma gondii is a single-celled parasite that infects nearly all warm-blooded animals,including humans(Montoya and Liesenfeld,2004).It occurs worldwide and can persist for a lifetime in mammals.Humans get infected by eating undercooked meat of animals containing the tissue cysts of this parasite.In immune-competent individuals,T. 展开更多
关键词 functional redundancy tissue cysts Toxoplasma gondii mitochondrial mg mn dependent protein phosphatases toxoplasma gondii
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Improved Aerial Video Compression for UA V System Based on Historical Background Redundancy
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作者 Chuanao Jiang Jin Xu Liuguo Yin 《Tsinghua Science and Technology》 2025年第6期2366-2383,共18页
In an increasing number of area inspection applications,such as powerline inspection and sewage disposal monitoring,Unmanned Aerial Vehicles(UAVs)are used for capturing and transmitting on-site videos.Existing UAV vid... In an increasing number of area inspection applications,such as powerline inspection and sewage disposal monitoring,Unmanned Aerial Vehicles(UAVs)are used for capturing and transmitting on-site videos.Existing UAV video compressions employ Advanced Video Coding(AVC)or High Efficiency Video Coding(HEvC)encoders to eliminate intra-frame and short-term inter-frame redundancy,while these methods still face challenges in achieving high compression efficiency due to the high captured video bitrate and limited transmission capacity.In this paper,we further consider that UAVs revisit the same area and capture videos from different viewpoints,hence the Long-term Historical Background Redundancy(LHBR)exists among revisited video clips.Thus,we leverage the LHBR caused by UAV revisits,and propose a high-efficiency aerial video compression for UAVs.Our method comprises three steps:Firstly,we propose a lightweight method based on a spatial correlation model to select the most correlated reference frames from historical video database.Then,we design a Historical Reference Background Frame(HBRF)generation algorithm by alternately using the keypoint-based and telemetry-assisted alignments to align the selected frames with current frame.Finally,we use the generated HBRF as a reference frame to eliminate the LHBR within I-frames.Our proposed method has been experimentally proven to reduce Bjøntegaard-Delta bitrate(BD-bitrate)by 42.83%or enhance Bjøntegaard-Delta Peak Signal-to-Noise Ratio(BD-PSNR)by 2.98 dB over original HEVC,and take 29.3%of the encoding time needed for existing LHBR based compressions. 展开更多
关键词 Unmanned Aerial Vehicle(UAV) Aerial Video Compression(AVC) Long-term Historical Background redundancy(LHBR)
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Intelligent Dynamic Heterogeneous Redundancy Architecture for IoT Systems 被引量:2
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作者 Zhang Han Wang Yu +2 位作者 Liu Hao Lin Hongyu Chen Liquan 《China Communications》 SCIE CSCD 2024年第7期291-306,共16页
The conventional dynamic heterogeneous redundancy(DHR)architecture suffers from the security threats caused by the stability differences and similar vulnerabilities among the executors.To overcome these challenges,we ... The conventional dynamic heterogeneous redundancy(DHR)architecture suffers from the security threats caused by the stability differences and similar vulnerabilities among the executors.To overcome these challenges,we propose an intelligent DHR architecture,which is more feasible by intelligently combining the random distribution based dynamic scheduling algorithm(RD-DS)and information weight and heterogeneity based arbitrament(IWHA)algorithm.In the proposed architecture,the random distribution function and information weight are employed to achieve the optimal selection of executors in the process of RD-DS,which avoids the case that some executors fail to be selected due to their stability difference in the conventional DHR architecture.Then,through introducing the heterogeneity to restrict the information weights in the procedure of the IWHA,the proposed architecture solves the common mode escape issue caused by the existence of multiple identical error output results of similar vulnerabilities.The experimental results characterize that the proposed architecture outperforms in heterogeneity,scheduling times,security,and stability over the conventional DHR architecture under the same conditions. 展开更多
关键词 dynamic heterogeneous redundancy HETEROGENEITY IoT security security defense
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Construction and kinematic performance analysis of a suspension support for wind tunnel tests of spinning projectiles based on wire-driven parallel robot with kinematic redundancy 被引量:2
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作者 Zhou ZHU Lu SHI +2 位作者 Cong HE Lei ZHAN Qi LIN 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2024年第12期404-415,共12页
This paper presents a novel suspension support tailored for wind tunnel tests of spinning projectiles based on Wire-Driven Parallel Robot(WDPR),uniquely characterized by an SPM(Spinning Projectile Model)-centered mobi... This paper presents a novel suspension support tailored for wind tunnel tests of spinning projectiles based on Wire-Driven Parallel Robot(WDPR),uniquely characterized by an SPM(Spinning Projectile Model)-centered mobile platform.First,an SPM-centered mobile platform,featuring two redundant and another unconstrained Degree of Freedom(DOF),and its suspension support mechanism are designed together,collectively constructing a WDPR endowed with kinematic redundancy.Afterward,the kinematics of the mechanism,boundary equations for the redundant DOFs,and relevant kinematic performance indices are then proposed and formulated.The results from both prototype experiments and numerical assessments are presented.The capability of the support mechanism to replicate the complex coupled motions of the SPM is verified by the experimental results,while the proposed kinematics and boundary equations are also validated.Furthermore,it is revealed by numerical assessments that the redundant DOFs of the mobile platform exert a minimal impact on the kinematic performance of the suspension support.Finally,the optimal global attitude performance is obtained when these DOFs are set to zero if they are restricted to constants.However,local attitude performance can be further improved by the variable values. 展开更多
关键词 Suspension support Wire-Driven Parallel Robot(WDPR) Spinning Projectile Model(SPM) Wind tunnels Kinematic performance analysis Kinematic redundancy
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Analysis of wheel-rail adhesion redundancy considering the thirdbody medium on the rail surface 被引量:1
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作者 Chun Tian Gengwei Zhai +2 位作者 Mengling Wu Jiajun Zhou Yaojie Li 《Railway Sciences》 2024年第2期156-176,共21页
Purpose–In response to the problem of insufficient traction/braking adhesion force caused by the existence of the third-body medium on the rail surface,this study aims to analyze the utilization of wheel-rail adhesio... Purpose–In response to the problem of insufficient traction/braking adhesion force caused by the existence of the third-body medium on the rail surface,this study aims to analyze the utilization of wheel-rail adhesion coefficient under different medium conditions and propose relevant measures for reasonable and optimized utilization of adhesion to ensure the traction/braking performance and operation safety of trains.Design/methodology/approach–Based on the PLS-160 wheel-rail adhesion simulation test rig,the study investigates the variation patterns of maximum utilized adhesion characteristics on the rail surface under different conditions of small creepage and large slip.Through statistical analysis of multiple sets of experimental data,the statistical distribution patterns of maximum utilized adhesion on the rail surface are obtained,and a method for analyzing wheel-rail adhesion redundancy based on normal distribution is proposed.The study analyzes the utilization of traction/braking adhesion,as well as adhesion redundancy,for different medium under small creepage and large slip conditions.Based on these findings,relevant measures for the reasonable and optimized utilization of adhesion are derived.Findings–When the third-body medium exists on the rail surface,the train should adopt the low-level service braking to avoid the braking skidding by extending the braking distance.Compared with the current adhesion control strategy of small creepage,adopting appropriate strategies to control the train’s adhesion coefficient near the second peak point of the adhesion coefficient-slip ratio curve in large slip can effectively improve the traction/braking adhesion redundancy and the upper limit of adhesion utilization,thereby ensuring the traction/braking performance and operation safety of the train.Originality/value–Most existing studies focus on the wheel-rail adhesion coefficient values and variation patterns under different medium conditions,without considering whether the rail surface with different medium can provide sufficient traction/braking utilized adhesion coefficient for the train.Therefore,there is a risk of traction overspeeding/braking skidding.This study analyzes whether the rail surface with different medium can provide sufficient traction/braking utilized adhesion coefficient for the train and whether there is redundancy.Based on these findings,relevant measures for the reasonable and optimized utilization of adhesion are derived to further ensure operation safety of the train. 展开更多
关键词 Wheel-rail adhesion redundancy PLS-160 wheel-rail adhesion simulation test rig Normal distribution Utilized adhesion coefficient
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Multi-Label Feature Selection Based on Improved Ant Colony Optimization Algorithm with Dynamic Redundancy and Label Dependence
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作者 Ting Cai Chun Ye +5 位作者 Zhiwei Ye Ziyuan Chen Mengqing Mei Haichao Zhang Wanfang Bai Peng Zhang 《Computers, Materials & Continua》 SCIE EI 2024年第10期1157-1175,共19页
The world produces vast quantities of high-dimensional multi-semantic data.However,extracting valuable information from such a large amount of high-dimensional and multi-label data is undoubtedly arduous and challengi... The world produces vast quantities of high-dimensional multi-semantic data.However,extracting valuable information from such a large amount of high-dimensional and multi-label data is undoubtedly arduous and challenging.Feature selection aims to mitigate the adverse impacts of high dimensionality in multi-label data by eliminating redundant and irrelevant features.The ant colony optimization algorithm has demonstrated encouraging outcomes in multi-label feature selection,because of its simplicity,efficiency,and similarity to reinforcement learning.Nevertheless,existing methods do not consider crucial correlation information,such as dynamic redundancy and label correlation.To tackle these concerns,the paper proposes a multi-label feature selection technique based on ant colony optimization algorithm(MFACO),focusing on dynamic redundancy and label correlation.Initially,the dynamic redundancy is assessed between the selected feature subset and potential features.Meanwhile,the ant colony optimization algorithm extracts label correlation from the label set,which is then combined into the heuristic factor as label weights.Experimental results demonstrate that our proposed strategies can effectively enhance the optimal search ability of ant colony,outperforming the other algorithms involved in the paper. 展开更多
关键词 Multi-label feature selection ant colony optimization algorithm dynamic redundancy high-dimensional data label correlation
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Dynamic Modeling and Adaptive Control of Cable-Driven Redundant Manipulator
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作者 Zihao Wang Haifeng Zhang +1 位作者 Tengfei Tang Qinchuan Li 《Chinese Journal of Mechanical Engineering》 2025年第4期282-299,共18页
A cable-driven redundant manipulator(CDRM)characterized by redundant degrees of freedom and a lightweight,slender design can perform tasks in confined and restricted spaces efficiently.However,the complex multistage c... A cable-driven redundant manipulator(CDRM)characterized by redundant degrees of freedom and a lightweight,slender design can perform tasks in confined and restricted spaces efficiently.However,the complex multistage coupling between drive cables and passive joints in CDRM leads to a challenging dynamic model with difficult parameter identification,complicating the efforts to achieve accurate modeling and control.To address these challenges,this paper proposes a dynamic modeling and adaptive control approach tailored for CDRM systems.A multilevel kinematic model of the cable-driven redundant manipulator is presented,and a screw theory is employed to represent the cable tension and cable contact forces as spatial wrenches,which are equivalently mapped to joint torque using the principle of virtual work.This approach simplifies the mapping process while maintaining the integrity of the dynamic model.A recursive method is used to compute cable tension section-by-section for enhancing the efficiency of inverse dynamics calculations and meeting the high-frequency demands of the controller,thereby avoiding large matrix operations.An adaptive control method is proposed building on this foundation,which involves the design of a dynamic parameter adaptive controller in the joint space to simplify the linearization process of the dynamic equations along with a closed-loop controller that incorporates motor parameters in the driving space.This approach improves the control accuracy and dynamic performance of the CDRM under dynamic uncertainties.The accuracy and computational efficiency of the dynamic model are validated through simulations,and the effectiveness of the proposed control method is demonstrated through control tests.This paper presents a dynamic modeling and adaptive control approach for CDRM to enhance accuracy and performance under dynamic uncertainties. 展开更多
关键词 Cable-driven redundant manipulator DYNAMICS Screw theory Recursive method Adaptive control
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Cooperative Collision Avoidance Control with Relative Velocity Information for Redundant Dual-arm Robotic Manipulators
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作者 Jinyue Liu Chao Xu +2 位作者 Xiaohui Jia Yi Wu Tiejun Li 《Journal of Bionic Engineering》 2025年第3期1111-1125,共15页
In this paper,a novel cooperative collision avoidance control strategy with relative velocity information for redundant robotic manipulators is derived to guarantee the behavioral safety of robots in the cooperative o... In this paper,a novel cooperative collision avoidance control strategy with relative velocity information for redundant robotic manipulators is derived to guarantee the behavioral safety of robots in the cooperative operational task.This strategy can generate the collision-free trajectory of the robotic links in real-time,which is to realize that the robot can avoid moving obstacles less conservatively and ensure tracking accuracy of terminal end-effector tasks in performing cooperative tasks.For the case where there is interference between the moving obstacle and the desired path of the robotic end-effector,the method inherits the null-space-based self-motion characteristics of the redundant manipulator,integrates the relative motion information,and uses the improved artificial potential field method to design the control items,which are used to generate the collision avoidance motion and carry out moving obstacles smoothly and less conservatively.At the same time,the strategy maintains the kinematic constraint relationship of dual-arm cooperatives,to meet the real-time collision avoidance task under collaborative tasks.Finally,the algorithm simulation indicates that the method can better ensure the tracking accuracy of the end-effector task and carry out moving obstacles smoothly.The experimental results show that the method can generate the real-time collision-free trajectory of the robot in the cooperative handling task,and the joint movement is continuous and stable. 展开更多
关键词 redundant dual-arm robotic manipulators Cooperative operational tasks Collision avoidance Relative velocity information
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Design of Electrical/Mechanical Hybrid 4-Redundancy Brushless DC Torque Motor 被引量:8
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作者 郭宏 王巍 +1 位作者 邢伟 李艳明 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2010年第2期211-215,共5页
This article presents a novel electrical/mechanical hybrid 4-redundancy brushless DC torque motor (BLDCM), which has found applications in direct drive actuators (DDA) of aerial vehicles. This motor is characteris... This article presents a novel electrical/mechanical hybrid 4-redundancy brushless DC torque motor (BLDCM), which has found applications in direct drive actuators (DDA) of aerial vehicles. This motor is characteristic of electrical/mechanical hybrid 4-redundancy by securing two stators along with two rotors on the same shaft. Each stator contains two sets of windings embed- ded in separated slots. Furthermore, compared to the scheme of two electrical dual-redundancy BLDCMs linked by a mechanical transmission, the proposed motor has lower volume and lighter weight, eliminates the nonlinearity caused by the gap of the me- chanical transmission, moderates the requirement for the torque balance between redundancies and reduces the cogging torque by shifting the magnets. Both magnetic circuit calculation and the finite element analysis (FEA) of the electromagnetic field are conducted to optimize the design process. A prototype motor has been produced and tested. The results indicate that its perform- ances comply with the requirements presented by designers. Moreover, the position frequency response of the prototype in the DDA's unloaded situation has also demonstrated the fulfillment of desired dynamic characteristics. 展开更多
关键词 brushless DC motor redundancy actuators electric motor design finite element method
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Fast Online Approximation for Hard Support Vector Regression and Its Application to Analytical Redundancy for Aeroengines 被引量:6
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作者 赵永平 孙健国 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2010年第2期145-152,共8页
The hard support vector regression attracts little attention owing to the overfitting phenomenon. Recently, a fast offiine method has been proposed to approximately train the hard support vector regression with the ge... The hard support vector regression attracts little attention owing to the overfitting phenomenon. Recently, a fast offiine method has been proposed to approximately train the hard support vector regression with the generation performance comparable to the soft support vector regression. Based on this achievement, this article advances a fast online approximation called the hard sup- port vector regression (FOAHSVR for short). By adopting the greedy stagewise and iterative strategies, it is capable of online estimating parameters of complicated systems. In order to verify the effectiveness of the FOAHSVR, an FOAHSVR-based analytical redundancy for aeroengines is developed. Experiments on the sensor failure and drift evidence the viability and feasibility of the analytical redundancy for aeroengines together with its base--FOAHSVR. In addition, the FOAHSVR is anticipated to find applications in other scientific-technical fields. 展开更多
关键词 support vector machines parameter estimation sensor fault analytical redundancy aeroengines
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REDUNDANCY TECHNOLOGY FOR AIRCRAFT MULTI-CHANNEL DC POWER SUPPLY SYSTEM 被引量:2
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作者 杨善水 魏秦华 +2 位作者 黄仙密 居蓉蓉 王莉 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 2007年第4期305-309,共5页
The redundancy technology for the aircraft multi-channel DC electrical power supply system is studied. In this system, the key loads can obtain power from seven sources. The direct current bus power control unit (DC ... The redundancy technology for the aircraft multi-channel DC electrical power supply system is studied. In this system, the key loads can obtain power from seven sources. The direct current bus power control unit (DC BPCU) is put forward to manage the power supply system automatically. The redundancy innovation is also applied in both hardware and software of DC BPCU. Furthermore, redundancy fault diagnosis is discussed through the existing parts. Experiments and applications show that the proposed aircraft DC power supply system possesses many advantages of high reliability, high automation and so on. 展开更多
关键词 redundant power supply bus power control unit(BPCU) redundancy hardware redundancy software
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关于不使用Hash和Redundancy函数签密方案的分析与改进 被引量:2
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作者 柏骏 张串绒 王珏 《空军工程大学学报(自然科学版)》 CSCD 北大核心 2010年第1期91-94,共4页
在实际应用中,前向安全性和公开验证性对密码系统来说是非常重要的。分析了不使用Hash和Redundancy函数的签密方案的前向安全性和公开验证性,分析表明该方案不具备前向安全性和公开验证性。分别就其前向安全性和公开验证性提出了相应的... 在实际应用中,前向安全性和公开验证性对密码系统来说是非常重要的。分析了不使用Hash和Redundancy函数的签密方案的前向安全性和公开验证性,分析表明该方案不具备前向安全性和公开验证性。分别就其前向安全性和公开验证性提出了相应的改进方案,并对方案进行了理论上的证明。改进方案克服了原方案中不具备前向安全性或公开验证性的缺陷;而且从效率上来分析,并没有明显增加计算量或传输量。 展开更多
关键词 密码学 签密 HASH redundancy 前向安全性 公开验证性
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不使用Hash和Redundancy函数的有序多重数字签名方案 被引量:1
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作者 刘振 余昭平 董涛 《计算机工程与应用》 CSCD 北大核心 2007年第23期116-118,123,共4页
现有的有序多重数字签名方案都使用了Hash函数和消息冗余函数,这必将承受由Hash函数和消息冗余函数带来的安全威胁。首先指出了施方案(文献[1])中存在的安全性问题,随后利用椭圆曲线密码算法设计了一个新的有序多重数字签名方案,该方案... 现有的有序多重数字签名方案都使用了Hash函数和消息冗余函数,这必将承受由Hash函数和消息冗余函数带来的安全威胁。首先指出了施方案(文献[1])中存在的安全性问题,随后利用椭圆曲线密码算法设计了一个新的有序多重数字签名方案,该方案不使用Hash函数和消息冗余函数,减少了这方面所带来的安全威胁;取消了施方案里的签名中心,避免了该签名中心的参与导致计算瓶颈的产生;所有消息均公开,签名者可以共同通过验证来发现伪签名和成员内部的欺诈行为。该文方案能够克服施方案的安全问题,并且计算量小,结构简单,具有一定的实用价值。 展开更多
关键词 有序 多重数字签名 HASH函数 冗余函数
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Application of Analytic Redundancy-based Fault Diagnosis of Sensors to Onboard Maintenance System 被引量:9
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作者 CHI Chengzhi ZHANG Weiguo LIU Xiaoxiong 《Chinese Journal of Aeronautics》 SCIE EI CSCD 2012年第2期236-242,共7页
Analytic redundancy-based fault diagnosis technique (ARFDT) is applied to onboard maintenance system (OMS). The principle of the proposed ARFDT scheme is to design a redundancy configuration using ARFDT to enhance... Analytic redundancy-based fault diagnosis technique (ARFDT) is applied to onboard maintenance system (OMS). The principle of the proposed ARFDT scheme is to design a redundancy configuration using ARFDT to enhance the functions of redundancy management and built in test equipment (BITE) monitor. Redundancy configuration for dual-redundancy and analytic redundancy is proposed, in which, the fault diagnosis includes detection and isolation. In order to keep the balance between rapid diagnosis and binary hypothesis, a filter together with an elapsed time limit is designed for sequential probability ratio test (SPRT) in the process of isolation. Diagnosis results would be submitted to central maintenance computer (CMC) together with BITE information. Moreover, by adopting reconstruction, the designed method not only provides analytic redundancy to help redundancy management, but also compensates the output when both of the sensors of the same type are faulty. Our scheme is applied to an aircraft’s sensors in a simulation experiment, and the results show that the proposed filter SPRT (FSPRT) saves at least 50% of isolation time than Wald SPRT (WSPRT). Also, effectiveness, practicability and rapidity of the proposed scheme can be successfully achieved in OMS. 展开更多
关键词 fault detection analytic redundancy sequential probability ratio test (SPRT) onboard maintenance system (OMS) redundancy management SENSORS
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Modeling of reliability and performance assessment of a dissimilar redundancy actuation system with failure monitoring 被引量:12
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作者 Wang Shaoping Cui Xiaoyu +2 位作者 Shi Jian Mileta M.Tomovic Jiao Zongxia 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2016年第3期799-813,共15页
Actuation system is a vital system in an aircraft, providing the force necessary to move flight control surfaces. The system has a significant influence on the overall aircraft performance and its safety. In order to ... Actuation system is a vital system in an aircraft, providing the force necessary to move flight control surfaces. The system has a significant influence on the overall aircraft performance and its safety. In order to further increase already high reliability and safety, Airbus has imple- mented a dissimilar redundancy actuation system (DRAS) in its aircraft. The DRAS consists of a hydraulic actuation system (HAS) and an electro-hydrostatic actuation system (EHAS), in which the HAS utilizes a hydraulic source (HS) to move the control surface and the EHAS utilizes an elec- trical supply (ES) to provide the motion force. This paper focuses on the performance degradation processes and fault monitoring strategies of the DRAS, establishes its reliability model based on the generalized stochastic Petri nets (GSPN), and carries out a reliability assessment considering the fault monitoring coverage rate and the false alarm rate. The results indicate that the proposed reli- ability model of the DRAS, considering the fault and redundancy degradation process and identify monitoring, can express its fault logical relation potential safety hazards. 展开更多
关键词 Dissimilar redundancy actu-ation system Electro-hydraulic actuationsystem Fault monitoring Generalized stochastic Petrinets Performance degradation
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Dynamics and Control of a Novel 3-DOF Parallel Manipulator with Actuation Redundancy 被引量:9
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作者 Xue-Mei Niu Guo-Qin Gao +1 位作者 Xin-Jun Liu Zhi-Da Bao 《International Journal of Automation and computing》 EI CSCD 2013年第6期552-562,共11页
This paper deals with the dynamics and control of a novel 3-degrees-of-freedom (DOF) parallel manipulator with actuation redundancy. According to the kinematics of the redundant manipulator, the inverse dynamic equa... This paper deals with the dynamics and control of a novel 3-degrees-of-freedom (DOF) parallel manipulator with actuation redundancy. According to the kinematics of the redundant manipulator, the inverse dynamic equation is formulated in the task space by using the Lagrangian formalism, and the driving force is optimized by utilizing the minimal 2-norm method. Based on the dynamic model, a synchronized sliding mode control scheme based on contour error is proposed to implement accurate motion tracking control. Additionally, an adaptive method is introduced to approximate the lumped uncertainty of the system and provide a chattering-free control. The simulation results indicate the effectiveness of the proposed approaches and demonstrate the satisfactory tracking performance compared to the conventional controller in the presence of the parameter uncertainties and un-modelled dynamics for the motion control of manipulators. 展开更多
关键词 Parallel manipulator redundant actuation dynamics modelling sliding mode control weighed integral gain reachinglaw.
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Two optimization algorithms for solving robotics inverse kinematics with redundancy 被引量:5
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作者 Jianxin XU, Wei WANG, Yuanguang SUN (Department of Electrical and Computer Engineering, National University of Singapore, Singapore 117576) 《控制理论与应用(英文版)》 EI 2010年第2期166-175,共10页
The kinematic redundancy in a robot leads to an infinite number of solutions for inverse kinematics, which implies the possibility to select a 'best' solution according to an optimization criterion. In this pa... The kinematic redundancy in a robot leads to an infinite number of solutions for inverse kinematics, which implies the possibility to select a 'best' solution according to an optimization criterion. In this paper, two optimization objective functions are proposed, aiming at either minimizing extra degrees of freedom (DOFs) or minimizing the total potential energy of a multilink redundant robot. Physical constraints of either equality or inequality types are taken into consideration in the objective functions. Since the closed-form solutions do not exist in general for highly nonlinear and constrained optimization problems, we adopt and develop two numerical methods, which are verified to be effective and precise in solving the two optimization problems associated with the redundant inverse kinematics. We first verify that the well established trajectory following method can precisely solve the two optimization problems, but is computation intensive. To reduce the computation time, a sequential approach that combines the sequential quadratic programming and iterative Newton-Raphson algorithm is developed. A 4-DOF Fujitsu Hoap-1 humanoid robot arm is used as a prototype to validate the effectiveness of the proposed optimization solutions. 展开更多
关键词 Inverse kinematics redundant robot Objective function OPTIMIZATION Numerical approach
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New approach to eliminate structural redundancy in case resource pools using α mutual information 被引量:6
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作者 Man Xu Haiyan Yu Jiang Shen 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2013年第4期625-633,共9页
Structural redundancy elimination in case resource pools (CRP) is critical for avoiding performance bottlenecks and maintaining robust decision capabilities in cloud computing services. For these purposes, this pape... Structural redundancy elimination in case resource pools (CRP) is critical for avoiding performance bottlenecks and maintaining robust decision capabilities in cloud computing services. For these purposes, this paper proposes a novel approach to ensure redundancy elimination of a reasoning system in CRP. By using α entropy and mutual information, functional measures to eliminate redundancy of a system are developed with respect to a set of outputs. These measures help to distinguish both the optimal feature and the relations among the nodes in reasoning networks from the redundant ones with the elimination criterion. Based on the optimal feature and its harmonic weight, a model for knowledge reasoning in CRP (CRPKR) is built to complete the task of query matching, and the missing values are estimated with Bayesian networks. Moreover, the robustness of decisions is verified through parameter analyses. This approach is validated by the simulation with benchmark data sets using cloud SQL. Compared with several state-of-the-art techniques, the results show that the proposed approach has a good performance and boosts the robustness of decisions. 展开更多
关键词 case resource pool (CRP) knowledge reasoning redundancy elimination α mutual information robust decision.
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Gene redundancy and gene compensation:An updated view 被引量:5
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作者 Jinrong Peng 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2019年第7期329-333,共5页
Gene knockdown approaches using antisense oligo nucleotides or analogs such as siRNAs and morpholinos have been widely adopted to study gene functions although the off-target issue has been always a concern in these s... Gene knockdown approaches using antisense oligo nucleotides or analogs such as siRNAs and morpholinos have been widely adopted to study gene functions although the off-target issue has been always a concern in these studies.On the other hand,classic genetic analysis relies on the availability of loss-offunction or gain-of-function mutants.The fast development of genome editing technologies such as TALEN and CRISPR/Cas9 has greatly facilitated the generation of null mutants for the functional studies of target genes in a variety of organisms such as zebrafish.Surprisingly,an unexpected discrepancy was observed between morphant phenotype and mutant phenotype for many genes in zebrafish,i.e.,while the morphant often displays an obvious phenotype,the corresponding null mutant appears relatively normal or only exhibits a mild phenotype due to gene compensation.Two recent reports have partially answered this intriguing question by showing that a pre-mature termination codon and homologous sequence are required to elicit the gene compensation and the histone modifying complex COMPASS is involved in activating the expression of the compensatory genes.Here,I summarize these exciting new progress and try to redefine the concept of genetic compensation and gene compensation. 展开更多
关键词 GENE redundancy GENE COMPENSATION GENETIC COMPENSATION Non-sense-mediated RNA decay(NMD) COMPASS complex GENETIC model system Zebrafish Capn3 Upf3a
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