At the first working meeting of the 'Key Technical Standard PromotionProject', an important project of the national scientific and technical support plan during the'11th Five Year' held recently in Bei...At the first working meeting of the 'Key Technical Standard PromotionProject', an important project of the national scientific and technical support plan during the'11th Five Year' held recently in Beijing, the first group of 11 research topics for the 'KeyTechnical Standard Promotion Project' was formally introduced. According to Ms. Yu Xinli, who is incharge of the project as Deputy Director of the China National Institute of Standardization, theproject comprises four aspects: the international standards key breakthrough project, the technicalstandards promotion project of adapting technical trade measures, the technical standards innovationproject of basic public welfare, and the technical standard enhancement project of public security.展开更多
Montmorency tart cherries(MTC)are rich in polyphenols and have well-documented health benefits,such as antioxidant and anti-inflammatory properties.These benefits may be attributed to secondary metabolites formed from...Montmorency tart cherries(MTC)are rich in polyphenols and have well-documented health benefits,such as antioxidant and anti-inflammatory properties.These benefits may be attributed to secondary metabolites formed from primary polyphenols,but their bioavailability in humans and their impact on short-chain fatty acid(SCFAs)biosynthesis remain inadequately studied.This secondary analysis assessed the bioavailability of MTC polyphenols,their conversion to secondary metab-olites,and their effect on SCFAs in humans.Plasma and stool samples from a randomized clinical trial were analyzed using targeted triple quadrupole LC-MS/MS and GC-MS/MS.Analyses revealed phase II conjugates and microbial derivatives in plasma and stool,as well as SCFAs in stool.14 plasma metabolites were identified,including conjugated forms of epicatechin and naringenin,along with microbial catabolites like 4-hydroxyphenylacetic acid and isovanillic acid.Stool analysis identified 8 secondary metabolites,such as vanillic acid and 3-hydroxyphenylpropionic acid,indicating colonic microbial degradation of anthocyanins and flavan-3-ols.SCFAs(acetate,propionate,and butyrate)were quantified,revealing formulation-dependent differences between MTC juice concentrate and freeze-dried powder.MTC polyphenols are absorbed as conjugated forms and undergo extensive microbial catabolism in the colon,yielding phenolic acids and SCFAs.These results underscore the dual roles of host and microbial metabolism in the bioavailability of tart cherry polyphenols and provide initial evidence linking product formulation to SCFA production.Further studies are necessary to determine the functional relevance of these secondary metabolites.展开更多
Tart cherry(Prunus cerasus L.)is a substantial source of polyphenolic compounds,including anthocyanins,flavonoids,and phenolic acids,which contribute to a range of biological effects.This review synthesizes peerreview...Tart cherry(Prunus cerasus L.)is a substantial source of polyphenolic compounds,including anthocyanins,flavonoids,and phenolic acids,which contribute to a range of biological effects.This review synthesizes peerreviewed studies published from 2018 to 2025,concentrating on the polyphenolic composition and bioactivities of tart cherry and its derivatives,while excluding research related to exercise.Identified health benefits encompass antioxidant,anti-inflammatory,antihypertensive,cardioprotective,anticancer,neuroprotective,antimicrobial,sleep-enhancing,anti-aging,uric acid reduction,and a role in bone loss.However,inconsistencies in study outcomes,variations in dosage,and heterogeneous populations limit broad conclusions.Importantly,there remains a lack of high-quality,long-term randomized controlled clinical studies to confirm these effects and clarify the mechanisms involved.A significant research gap persists in understanding the bioavailability of polyphenols,particularly regarding their absorption,metabolism,and excretion.While some studies have reported their presence in urine and plasma,none have examined stool samples,which are essential for confirming systemic exposure and gut interaction.This review highlights the necessity for standardized clinical studies and deeper pharmacokinetic insights to substantiate the tart cherry role as a functional food and evidence-based nutraceutical.展开更多
Tart cherries are known for their high phenolic content and a plethora of health benefits pertaining to heart health,muscle recovery,sleep quality,inflammation,and arthritis,to name a few.However,maximizing the bioava...Tart cherries are known for their high phenolic content and a plethora of health benefits pertaining to heart health,muscle recovery,sleep quality,inflammation,and arthritis,to name a few.However,maximizing the bioavailability of these bioactive food components is often a challenge in the food and beverage industry.The aim of this research was to investigate the spray drying process for microencapsulation to increase the stability of compounds and improve their release properties,thereby resulting in enhanced bioavailability.In our study,we investigated the effects of micronization methods and microencapsulation using wall material combinations on the physical attributes,morphology,and chemical properties of spray-dried tart cherry microcapsules.Micronized and non-micronized pur´ee was spray-dried utilizing different ratios of maltodextrin(MD)and gum arabic(GA)as wall materials.The microcapsules were evaluated for process yield,color,hygroscopicity,particle surface shape using Scanning Electron Microscopy(SEM),anthocyanin encapsulation efficiency,antioxidants and phenolics.The results demonstrated that the total phenolics,flavonoid content,and antioxidant activity increased for all wall material conditions with a reduction in particle size.The findings suggest that high-pressure homogenization(HPH)and the combination of MD and GA in an equal ratio(MD:GA 15%:15%)can effectively improve the extractability of phenolics and antioxidants.This study underscores the potential of spray-dried fruit juice powders and contributes to filling the current knowledge gap regarding the microencapsulation of tart cherries,particularly in the context of micronized fruit purées.展开更多
文摘At the first working meeting of the 'Key Technical Standard PromotionProject', an important project of the national scientific and technical support plan during the'11th Five Year' held recently in Beijing, the first group of 11 research topics for the 'KeyTechnical Standard Promotion Project' was formally introduced. According to Ms. Yu Xinli, who is incharge of the project as Deputy Director of the China National Institute of Standardization, theproject comprises four aspects: the international standards key breakthrough project, the technicalstandards promotion project of adapting technical trade measures, the technical standards innovationproject of basic public welfare, and the technical standard enhancement project of public security.
文摘Montmorency tart cherries(MTC)are rich in polyphenols and have well-documented health benefits,such as antioxidant and anti-inflammatory properties.These benefits may be attributed to secondary metabolites formed from primary polyphenols,but their bioavailability in humans and their impact on short-chain fatty acid(SCFAs)biosynthesis remain inadequately studied.This secondary analysis assessed the bioavailability of MTC polyphenols,their conversion to secondary metab-olites,and their effect on SCFAs in humans.Plasma and stool samples from a randomized clinical trial were analyzed using targeted triple quadrupole LC-MS/MS and GC-MS/MS.Analyses revealed phase II conjugates and microbial derivatives in plasma and stool,as well as SCFAs in stool.14 plasma metabolites were identified,including conjugated forms of epicatechin and naringenin,along with microbial catabolites like 4-hydroxyphenylacetic acid and isovanillic acid.Stool analysis identified 8 secondary metabolites,such as vanillic acid and 3-hydroxyphenylpropionic acid,indicating colonic microbial degradation of anthocyanins and flavan-3-ols.SCFAs(acetate,propionate,and butyrate)were quantified,revealing formulation-dependent differences between MTC juice concentrate and freeze-dried powder.MTC polyphenols are absorbed as conjugated forms and undergo extensive microbial catabolism in the colon,yielding phenolic acids and SCFAs.These results underscore the dual roles of host and microbial metabolism in the bioavailability of tart cherry polyphenols and provide initial evidence linking product formulation to SCFA production.Further studies are necessary to determine the functional relevance of these secondary metabolites.
文摘Tart cherry(Prunus cerasus L.)is a substantial source of polyphenolic compounds,including anthocyanins,flavonoids,and phenolic acids,which contribute to a range of biological effects.This review synthesizes peerreviewed studies published from 2018 to 2025,concentrating on the polyphenolic composition and bioactivities of tart cherry and its derivatives,while excluding research related to exercise.Identified health benefits encompass antioxidant,anti-inflammatory,antihypertensive,cardioprotective,anticancer,neuroprotective,antimicrobial,sleep-enhancing,anti-aging,uric acid reduction,and a role in bone loss.However,inconsistencies in study outcomes,variations in dosage,and heterogeneous populations limit broad conclusions.Importantly,there remains a lack of high-quality,long-term randomized controlled clinical studies to confirm these effects and clarify the mechanisms involved.A significant research gap persists in understanding the bioavailability of polyphenols,particularly regarding their absorption,metabolism,and excretion.While some studies have reported their presence in urine and plasma,none have examined stool samples,which are essential for confirming systemic exposure and gut interaction.This review highlights the necessity for standardized clinical studies and deeper pharmacokinetic insights to substantiate the tart cherry role as a functional food and evidence-based nutraceutical.
文摘Tart cherries are known for their high phenolic content and a plethora of health benefits pertaining to heart health,muscle recovery,sleep quality,inflammation,and arthritis,to name a few.However,maximizing the bioavailability of these bioactive food components is often a challenge in the food and beverage industry.The aim of this research was to investigate the spray drying process for microencapsulation to increase the stability of compounds and improve their release properties,thereby resulting in enhanced bioavailability.In our study,we investigated the effects of micronization methods and microencapsulation using wall material combinations on the physical attributes,morphology,and chemical properties of spray-dried tart cherry microcapsules.Micronized and non-micronized pur´ee was spray-dried utilizing different ratios of maltodextrin(MD)and gum arabic(GA)as wall materials.The microcapsules were evaluated for process yield,color,hygroscopicity,particle surface shape using Scanning Electron Microscopy(SEM),anthocyanin encapsulation efficiency,antioxidants and phenolics.The results demonstrated that the total phenolics,flavonoid content,and antioxidant activity increased for all wall material conditions with a reduction in particle size.The findings suggest that high-pressure homogenization(HPH)and the combination of MD and GA in an equal ratio(MD:GA 15%:15%)can effectively improve the extractability of phenolics and antioxidants.This study underscores the potential of spray-dried fruit juice powders and contributes to filling the current knowledge gap regarding the microencapsulation of tart cherries,particularly in the context of micronized fruit purées.
