Alzheimer’s disease(AD)is a progressive neurodegenerative disorder characterized by the accumulation of amyloid-beta(Aβ)plaques and neurofibrillary tangles(NFTs)composed of hyperphosphorylated Tau protein tau tangle...Alzheimer’s disease(AD)is a progressive neurodegenerative disorder characterized by the accumulation of amyloid-beta(Aβ)plaques and neurofibrillary tangles(NFTs)composed of hyperphosphorylated Tau protein tau tangles,leading to cognitive decline and neuronal loss(Frisoni et al.2022;Self and Holtzman 2023).展开更多
基金supported by the National Natural Science Foundation of China(82471445 and 32170988 to R.L.)the Talent Scientific Fund of Lanzhou University(561120215 to R.L.).
文摘Alzheimer’s disease(AD)is a progressive neurodegenerative disorder characterized by the accumulation of amyloid-beta(Aβ)plaques and neurofibrillary tangles(NFTs)composed of hyperphosphorylated Tau protein tau tangles,leading to cognitive decline and neuronal loss(Frisoni et al.2022;Self and Holtzman 2023).
