Data-driven research on recycled aggregate concrete(RAC)has long faced the challenge of lacking a unified testing standard dataset,hindering accurate model evaluation and trust in predictive outcomes.This paper review...Data-driven research on recycled aggregate concrete(RAC)has long faced the challenge of lacking a unified testing standard dataset,hindering accurate model evaluation and trust in predictive outcomes.This paper reviews critical parameters influencing mechanical properties in 35 RAC studies,compiles four datasets encompassing these parameters,and compiles the performance and key findings of 77 published data-driven models.Baseline capability tests are conducted on the nine most used models.The paper also outlines advanced methodological frameworks for future RAC research,examining the principles and challenges of physics-informed neural networks(PINNs)and generative adversarial networks(GANs),and employs SHAP and PDP tools to interpret model behaviour and enhance transparency.Findings indicate a clear trend toward integrated systems,hybrid models,and advanced optimization strategies,with integrated tree-based models showing superior performance across various prediction tasks.Based on this comprehensive review,we offer a recommendation for future research on how AI can be effectively oriented in RAC studies to support practical deployment and build confidence in data-driven approaches.展开更多
This letter introduces the novel concept of Painlevé solitons—waves arising from the interaction between Painlevé waves and solitons in integrable systems.Painlevé solitons can also be viewed as solito...This letter introduces the novel concept of Painlevé solitons—waves arising from the interaction between Painlevé waves and solitons in integrable systems.Painlevé solitons can also be viewed as solitons propagating against a Painlevé wave background,in analogy to the established notion of elliptic solitons,which refers to solitons on an elliptic wave background.By employing a novel symmetry decomposition method aided by nonlocal residual symmetries,we explicitly construct (extended) Painlevé Ⅱ solitons for the Korteweg-de Vries equation and (extended) Painlevé Ⅳ solitons for the Boussinesq equation.展开更多
Energy storage-equipped photovoltaic(PV-storage)systems can meet frequency regulation requirements under various operating conditions,and their coordinated support for grid frequency has become a future trend.To addre...Energy storage-equipped photovoltaic(PV-storage)systems can meet frequency regulation requirements under various operating conditions,and their coordinated support for grid frequency has become a future trend.To address frequency stability issues caused by low inertia and weak damping,this paper proposes a multi-timescale frequency regulation coordinated control strategy for PV-storage integrated systems.First,a self-synchronizing control strategy for grid-connected inverters is designed based on DC voltage dynamics,enabling active inertia support while transmitting frequency variation information.Next,an energy storage inertia support control strategy is developed to enhance the frequency nadir,and an active frequency support control strategy for PV system considering a frequency regulation deadband is proposed,where the deadband value is determined based on the power regulation margin of synchronous generators,allowing the PV-storage system to adaptively switch between inertia support and primary frequency regulation under different disturbance conditions.This approach ensures system frequency stability while fully leveraging the regulation capabilities of heterogeneous resources.Finally,the real-time digital simulation results of the PV-storage integrated system demonstrate that,compared to existing control methods,the proposed strategy effectively reduces the rate of change of frequency and improves the frequency nadir under various disturbance scenarios,verifying its effectiveness.展开更多
Various application domains require the integration of distributed real-time or near-real-time systems with non-real-time systems.Smart cities,smart homes,ambient intelligent systems,or network-centric defense systems...Various application domains require the integration of distributed real-time or near-real-time systems with non-real-time systems.Smart cities,smart homes,ambient intelligent systems,or network-centric defense systems are among these application domains.Data Distribution Service(DDS)is a communication mechanism based on Data-Centric Publish-Subscribe(DCPS)model.It is used for distributed systems with real-time operational constraints.Java Message Service(JMS)is a messaging standard for enterprise systems using Service Oriented Architecture(SOA)for non-real-time operations.JMS allows Java programs to exchange messages in a loosely coupled fashion.JMS also supports sending and receiving messages using a messaging queue and a publish-subscribe interface.In this article,we propose an architecture enabling the automated integration of distributed real-time and non-real-time systems.We test our proposed architecture using a distributed Command,Control,Communications,Computers,and Intelligence(C4I)system.The system has DDS-based real-time Combat Management System components deployed to naval warships,and SOA-based non-real-time Command and Control components used at headquarters.The proposed solution enables the exchange of data between these two systems efficiently.We compare the proposed solution with a similar study.Our solution is superior in terms of automation support,ease of implementation,scalability,and performance.展开更多
Schizophrenia is characterized by psychotic symptoms,negative symptoms,and cognitive deficits,profoundly affecting individuals and their families.The etiology is multifactorial,involving genetic,endocrine,and immunolo...Schizophrenia is characterized by psychotic symptoms,negative symptoms,and cognitive deficits,profoundly affecting individuals and their families.The etiology is multifactorial,involving genetic,endocrine,and immunological risk factors.It is thought that schizophrenia is exclusively linked to alterations in brain structure and function,while the relationship between the brain and many organs may lack sufficient attention.Increasing evidence indicates abnormalities of the interactions between the brain and many organs in patients with schizophrenia.Inter-organ crosstalk affects the onset,course,and management of schizophrenia.Besides,the complex relationship between autonomic nervous system,endocrine system,and immune system further facilitates the development of schizophrenia.The present review summarizes the relationships between the brain and multiple organ systems in schizophrenia,providing new perspectives on the underlying pathophysiological mechanisms of schizophrenia.展开更多
Background:Diabetic cardiomyopathy(DCM)is a type of cardiomyopathy caused by long-term diabetes,characterized by abnormal myocardial structure and function,which can lead to heart failure.Berberine(BBR),a quaternary a...Background:Diabetic cardiomyopathy(DCM)is a type of cardiomyopathy caused by long-term diabetes,characterized by abnormal myocardial structure and function,which can lead to heart failure.Berberine(BBR),a quaternary ammonium alkaloid isolated from Coptidis Rhizoma,a traditional Chinese medicine,has superior anti-diabetic and heart-protective properties.The purpose of this study is to assess the impact of BBR on DCM.Methods:This study used a systems pharmacology approach to evaluate the related proteins and signalling pathways between BBR and DCM targets,combined with experimental validation using diabetic mouse heart sections.Microstructural and pathological changes were observed using Hematoxylin-eosin,Masson’s trichrome stain and wheat germ agglutinin staining.Immunofluorescence and western blot were used to determine protein expression.Results:The results indicate that BBR and DCM share 21 core relevant targets,with cross-targets predominantly located in mitochondrial,endoplasmic reticulum,and plasma membrane components.BBR exerts its main effects in improving DCM by maintaining mitochondrial integrity,particularly involving the PI3K-AKT-GSK3βand apoptosis signalling pathways.In addition,post-treatment changes in the key targets of BBR,including cysteine aspartate specific protease(Caspase)-3,phosphoinositide 3-kinase(PI3K)and mitochondria-related proteins,are suggestive of its efficacy.Conclusion:BBR crucially improves DCM by maintaining mitochondrial integrity,inhibiting apoptosis,and modulating PI3K-AKT-GSK3βsignaling.Further studies must address animal model limitations and validate clinical efficacy to understand BBR’s mechanisms fully and its potential clinical use.展开更多
This study presents a(2+1)-dimensional complex coupled dispersionless system.A Lax pair is proposed,and the Darboux transformation is employed to construct multisoliton solutions.These solutions exhibit a range of wav...This study presents a(2+1)-dimensional complex coupled dispersionless system.A Lax pair is proposed,and the Darboux transformation is employed to construct multisoliton solutions.These solutions exhibit a range of wave phenomena,including bright and dark solitons,S-shaped formations,parabolic profiles,and periodic wave patterns.Additionally,it is shown that the system is equivalent to the sine-Gordon equation and the negative flow of the modified Korteweg-de Vries hierarchy through appropriate transformations.展开更多
With the development of integrated power and gas distribution systems(IPGS)incorporating renewable energy sources(RESs),coordinating the restoration processes of the power distribution system(PS)and the gas distributi...With the development of integrated power and gas distribution systems(IPGS)incorporating renewable energy sources(RESs),coordinating the restoration processes of the power distribution system(PS)and the gas distribution system(GS)by utilizing the benefits of RESs enhances service restoration.In this context,this paper proposes a coordinated service restoration framework that considers the uncertainty in RESs and the bi-directional restoration interactions between the PS and GS.Additionally,a coordinated service restoration model is developed considering the two systems’interdependency and the GS’s dynamic characteristics.The objective is to maximize the system resilience index while adhering to operational,dynamic,restoration logic,and interdependency constraints.A method for managing uncertainties in RES output is employed,and convexification techniques are applied to address the nonlinear constraints arising from the physical laws of the IPGS,thereby reducing solution complexity.As a result,the service restoration optimization problem of the IPGS can be formulated as a computationally tractable mixed-integer second-order cone programming problem.The effectiveness and superiority of the proposed framework are demonstrated through numerical simulations conducted on the interdependent IEEE 13-bus PS and 9-node GS.The comparative results show that the proposed framework improves the system resilience index by at least 65.07%compared to traditional methods.展开更多
With the intensification of the energy crisis and the worsening greenhouse effect,the development of sustainable integrated energy systems(IES)has become a crucial direction for energy transition.In this context,this ...With the intensification of the energy crisis and the worsening greenhouse effect,the development of sustainable integrated energy systems(IES)has become a crucial direction for energy transition.In this context,this paper proposes a low-carbon economic dispatch strategy under the green hydrogen certificate trading(GHCT)and the ladder-type carbon emission trading(CET)mechanism,enabling the coordinated utilization of green and blue hydrogen.Specifically,a proton exchange membrane electrolyzer(PEME)model that accounts for dynamic efficiency characteristics,and a steam methane reforming(SMR)model incorporating waste heat recovery,are developed.Based on these models,a hydrogen production–storage–utilization framework is established to enable the coordinated deployment of green and blue hydrogen.Furthermore,the gas turbine(GT)unit are retrofitted using oxygenenriched combustion carbon capture(OCC)technology,wherein the oxygen produced by PEME is employed to create an oxygen-enriched combustion environment.This approach reduces energy waste and facilitates low-carbon power generation.In addition,the GHCT mechanism is integrated into the system alongside the ladder-type CET mechanism,and their complementary effects are investigated.A comprehensive optimization model is then formulated to simultaneously achieve carbon reduction and economic efficiency across the system.Case study results show that the proposed strategy reduces wind curtailment by 7.77%,carbon emissions by 65.98%,and total cost by 12.57%.This study offers theoretical reference for the low-carbon,economic,and efficient operation of future energy systems.展开更多
To address the issues of unclear carbon responsibility attribution,insufficient renewable energy absorption,and simplistic carbon trading mechanisms in integrated energy systems,this paper proposes an electricheat-hyd...To address the issues of unclear carbon responsibility attribution,insufficient renewable energy absorption,and simplistic carbon trading mechanisms in integrated energy systems,this paper proposes an electricheat-hydrogen integrated energy system(EHH-IES)optimal scheduling model considering carbon emission stream(CES)and wind-solar accommodation.First,the CES theory is introduced to quantify the carbon emission intensity of each energy conversion device and transmission branch by defining carbon emission rate,branch carbon intensity,and node carbon potential,realizing accurate tracking of carbon flow in the process of multi-energy coupling.Second,a stepped carbon pricing mechanism is established to dynamically adjust carbon trading costs based on the deviation between actual carbon emissions and initial quotas,strengthening the emission reduction incentive.Finally,a lowcarbon economic dispatch model is constructed with the objectives of minimizing operation cost,carbon trading cost,wind-solar curtailment penalty cost,and energy loss.Simulation results show that compared with the traditional economic dispatch scheme 3,the proposed schemel reduces carbon emissions by 53.97%and wind-solar curtailment by 68.89%with a 16.10%increase in total cost.This verifies that the model can effectively improve clean energy utilization and reduce carbon emissions,achieving low-carbon economic operation of EHH-IES,with CES theory ensuring precise carbon flow tracking across multi-energy links.展开更多
Reliable detection of weak phase signals under significant channel loss and complex noise environments is a crucial step for practical applications of optical integrated communication and sensing systems. In this lett...Reliable detection of weak phase signals under significant channel loss and complex noise environments is a crucial step for practical applications of optical integrated communication and sensing systems. In this letter, we propose and experimentally demonstrate an enhanced long-distance weak signal transmission method assisted by weak measurement. Performing heterodyne detection and light intensity compensation on two nearly symmetric post-selected paths, the method enables real-time estimation of a time-varying phase while maintaining robustness against technical noises proportional to light intensity or photon number, detector common-mode noise, and significant attenuation over long-distance transmission. Experimental results indicate a potential phase sensitivity at the level of 10-8rad even with a signal light intensity attenuation of 48.1 d B. Potentially, combining the adaptive adjustment strategy, the method may provide a viable solution in remote weak signal detection and extraction,thereby contributing to optical integrated communication and sensing.展开更多
It is of great significance to develop clean and new energy sources with high-efficient energy storage technologies,due to the excessive use of fossil energy that has caused severe environmental damage.There is great ...It is of great significance to develop clean and new energy sources with high-efficient energy storage technologies,due to the excessive use of fossil energy that has caused severe environmental damage.There is great interest in exploring advanced rechargeable lithium batteries with desirable energy and power capabilities for applications in portable electronics,smart grids,and electric vehicles.In practice,high-capacity and low-cost electrode materials play an important role in sustaining the progresses in lithium-ion batteries.This review aims at giving an account of recent advances on the emerging high-capacity electrode materials and summarizing key barriers and corresponding strategies for the practical viability of these electrode materials.Effective approaches to enhance energy density of lithium-ion batteries are to increase the capacity of electrode materials and the output operation voltage.On account of major bottlenecks of the power lithium-ion battery,authors come up with the concept of integrated battery systems,which will be a promising future for high-energy lithium-ion batteries to improve energy density and alleviate anxiety of electric vehicles.展开更多
In the missile-borne Strapdown Inertial Navigation System/Global Navigation Satellite System(SINS/GNSS)integrated navigation system,due to the factors such as the high dynamics,the signal blocking by obstacles,the sig...In the missile-borne Strapdown Inertial Navigation System/Global Navigation Satellite System(SINS/GNSS)integrated navigation system,due to the factors such as the high dynamics,the signal blocking by obstacles,the signal intefereces,etc.,there always exist pulse interferences or measurement information interruptions in the satellite receiver,which make nonstationary measurement process.The traditional Kalman Filter(KF)can tackle the state estimation problem under Gaussian white noise,but its performance will be significantly reduced under nonGaussian noises.In order to deal with the non-Gaussian conditions in the actual missile-borne SINS/GNSS integrated navigation systems,a Maximum Versoria Criterion Extended Kalman Filter(MVC-EKF)algorithm is proposed based on the MVC and the idea of M-estimation,which assigns a smaller weight to the anomalous measurements so as to suppress the influence of anomalous measurements on the state estimation while maintaining a relatively low calculation cost.Finally,the integrated navigation simulation experiments prove the effectiveness and robustness of the proposed algorithm.展开更多
We classify all positive solutions for the following integral system：{ui（x）=∫Rn1/│x-y│^n-α fi（u（y））dy,x∈R^n,i=1,…,m,0〈α〈n,and u（x）=（u1（x）,u2（x）…,um（x））.Here fi（u）, 1 ≤ i ≤m, monotone non...We classify all positive solutions for the following integral system：{ui（x）=∫Rn1/│x-y│^n-α fi（u（y））dy,x∈R^n,i=1,…,m,0〈α〈n,and u（x）=（u1（x）,u2（x）…,um（x））.Here fi（u）, 1 ≤ i ≤m, monotone nondecreasing are real-valued functions of homogeneous degree n＋α/n-α and are monotone nondecreasing with respect to all the independent variables U1, u2, ..., urn.In the special case n ≥ 3 and α = 2. we show that the above system is equivalent to thefollowing elliptic PDE system：This system is closely related to the stationary SchrSdinger system with critical exponents for Bose-Einstein condensate展开更多
In this paper, a distributed control scheme has been developed for consensus of single integrator multi-agent systems with directed fixed communication topology for arbitrarily large constant, time-varying or distribu...In this paper, a distributed control scheme has been developed for consensus of single integrator multi-agent systems with directed fixed communication topology for arbitrarily large constant, time-varying or distributed communication delays. It is proved that the closed loop control system can reach consensus with an exponential convergence rate if and only if the topology is quasi-strongly connected. Simulation results are also provided to demonstrate the effectiveness of the proposed controller.展开更多
The symmetry constraint and binary nonlinearization of Lax pairs for the super classical-Boussinesq hierarchy is obtained. Under the obtained symmetry constraint, the n-th flow of the super classical-Boussinesq hierar...The symmetry constraint and binary nonlinearization of Lax pairs for the super classical-Boussinesq hierarchy is obtained. Under the obtained symmetry constraint, the n-th flow of the super classical-Boussinesq hierarchy is decomposed into two super finite-dimensional integrable Hamiltonian systems, defined over the super-symmetry manifold with the corresponding dynamical variables x and tn. The integrals of motion required for Liouville integrability are explicitly given.展开更多
The Lax pair of the mixed Ablowitz-Kap-Newell-Segur （AKNS） system is obtained from compatibility condition. Hirota＇s bilinear form is derived by some dependent variable transformation. Moreover, by means of the Wro...The Lax pair of the mixed Ablowitz-Kap-Newell-Segur （AKNS） system is obtained from compatibility condition. Hirota＇s bilinear form is derived by some dependent variable transformation. Moreover, by means of the Wronskian technique, the double Wronskian form of soliton solutions are found. Specially, the two-soliton solution is presented.展开更多
Multi-place nonlocal systems have attracted attention from many scientists.In this paper,we mainly review the recent progresses on two-place nonlocal systems(Alice-Bob systems)and four-place nonlocal models.Multi-plac...Multi-place nonlocal systems have attracted attention from many scientists.In this paper,we mainly review the recent progresses on two-place nonlocal systems(Alice-Bob systems)and four-place nonlocal models.Multi-place systems can firstly be derived from many physical problems by using a multiple scaling method with a discrete symmetry group including parity,time reversal,charge conjugates,rotations,field reversal and exchange transformations.Multiplace nonlocal systems can also be derived from the symmetry reductions of coupled nonlinear systems via discrete symmetry reductions.On the other hand,to solve multi-place nonlocal systems,one can use the symmetry-antisymmetry separation approach related to a suitable discrete symmetry group,such that the separated systems are coupled local ones.By using the separation method,all the known powerful methods used in local systems can be applied to nonlocal cases.In this review article,we take two-place and four-place nonlocal nonlinear Schr?dinger(NLS)systems and Kadomtsev-Petviashvili(KP)equations as simple examples to explain how to derive and solve them.Some types of novel physical and mathematical points related to the nonlocal systems are especially emphasized.展开更多
The reliability of quasi integrable and non-resonant Hamiltonian system under fractional Gaussian noise(fGn)excitation is studied.Noting rather flat fGn power spectral density(PSD)in most part of frequency band,the fG...The reliability of quasi integrable and non-resonant Hamiltonian system under fractional Gaussian noise(fGn)excitation is studied.Noting rather flat fGn power spectral density(PSD)in most part of frequency band,the fGn is innovatively regarded as a wide-band process.Then,the stochastic averaging method for quasi integrable Hamiltonian systems under wide-band noise excitation is applied to reduce 2n-dimensional original system into n-dimensional averaged ltd stochastic differential equations(SDEs).Reliability function and mean first passage time are obtained by solving the associated backward Kolmogorov equation and Pontryagin equation.The validity of the proposed procedure is tested by applying it to an example and comparing the numerical results with those from Monte Carlo simulation.展开更多
A new type of symmetry,ren-symmetry,describing anyon physics and corresponding topological physics,is proposed.Ren-symmetry is a generalization of super-symmetry which is widely applied in super-symmetric physics such...A new type of symmetry,ren-symmetry,describing anyon physics and corresponding topological physics,is proposed.Ren-symmetry is a generalization of super-symmetry which is widely applied in super-symmetric physics such as super-symmetric quantum mechanics,super-symmetric gravity,super-symmetric string theory,super-symmetric integrable systems and so on.Supersymmetry and Grassmann numbers are,in some sense,dual conceptions,and it turns out that these conceptions coincide for the ren situation,that is,a similar conception of ren-number(R-number)is devised for ren-symmetry.In particular,some basic results of the R-number and ren-symmetry are exposed which allow one to derive,in principle,some new types of integrable systems including ren-integrable models and ren-symmetric integrable systems.Training examples of ren-integrable KdV-type systems and ren-symmetric KdV equations are explicitly given.展开更多
文摘Data-driven research on recycled aggregate concrete(RAC)has long faced the challenge of lacking a unified testing standard dataset,hindering accurate model evaluation and trust in predictive outcomes.This paper reviews critical parameters influencing mechanical properties in 35 RAC studies,compiles four datasets encompassing these parameters,and compiles the performance and key findings of 77 published data-driven models.Baseline capability tests are conducted on the nine most used models.The paper also outlines advanced methodological frameworks for future RAC research,examining the principles and challenges of physics-informed neural networks(PINNs)and generative adversarial networks(GANs),and employs SHAP and PDP tools to interpret model behaviour and enhance transparency.Findings indicate a clear trend toward integrated systems,hybrid models,and advanced optimization strategies,with integrated tree-based models showing superior performance across various prediction tasks.Based on this comprehensive review,we offer a recommendation for future research on how AI can be effectively oriented in RAC studies to support practical deployment and build confidence in data-driven approaches.
基金supported by the National Natural Science Foundations of China (Grant Nos.12235007,12001424,12271324,and 12501333)the Natural Science Basic research program of Shaanxi Province (Grant Nos.2021JZ-21 and 2024JC-YBQN-0069)+3 种基金the China Postdoctoral Science Foundation (Grant Nos.2020M673332 and 2024M751921)the Fundamental Research Funds for the Central Universities (Grant No.GK202304028)the 2023 Shaanxi Province Postdoctoral Research Project (Grant No.2023BSHEDZZ186)Xi’an University,Xi’an Science and Technology Plan Wutongshu Technology Transfer Action Innovation Team(Grant No.25WTZD07)。
文摘This letter introduces the novel concept of Painlevé solitons—waves arising from the interaction between Painlevé waves and solitons in integrable systems.Painlevé solitons can also be viewed as solitons propagating against a Painlevé wave background,in analogy to the established notion of elliptic solitons,which refers to solitons on an elliptic wave background.By employing a novel symmetry decomposition method aided by nonlocal residual symmetries,we explicitly construct (extended) Painlevé Ⅱ solitons for the Korteweg-de Vries equation and (extended) Painlevé Ⅳ solitons for the Boussinesq equation.
基金supported by the State Grid Corporation of China under Grant for Science and Technology Projects(No.SGNXJYOOZWJS2500029).
文摘Energy storage-equipped photovoltaic(PV-storage)systems can meet frequency regulation requirements under various operating conditions,and their coordinated support for grid frequency has become a future trend.To address frequency stability issues caused by low inertia and weak damping,this paper proposes a multi-timescale frequency regulation coordinated control strategy for PV-storage integrated systems.First,a self-synchronizing control strategy for grid-connected inverters is designed based on DC voltage dynamics,enabling active inertia support while transmitting frequency variation information.Next,an energy storage inertia support control strategy is developed to enhance the frequency nadir,and an active frequency support control strategy for PV system considering a frequency regulation deadband is proposed,where the deadband value is determined based on the power regulation margin of synchronous generators,allowing the PV-storage system to adaptively switch between inertia support and primary frequency regulation under different disturbance conditions.This approach ensures system frequency stability while fully leveraging the regulation capabilities of heterogeneous resources.Finally,the real-time digital simulation results of the PV-storage integrated system demonstrate that,compared to existing control methods,the proposed strategy effectively reduces the rate of change of frequency and improves the frequency nadir under various disturbance scenarios,verifying its effectiveness.
文摘Various application domains require the integration of distributed real-time or near-real-time systems with non-real-time systems.Smart cities,smart homes,ambient intelligent systems,or network-centric defense systems are among these application domains.Data Distribution Service(DDS)is a communication mechanism based on Data-Centric Publish-Subscribe(DCPS)model.It is used for distributed systems with real-time operational constraints.Java Message Service(JMS)is a messaging standard for enterprise systems using Service Oriented Architecture(SOA)for non-real-time operations.JMS allows Java programs to exchange messages in a loosely coupled fashion.JMS also supports sending and receiving messages using a messaging queue and a publish-subscribe interface.In this article,we propose an architecture enabling the automated integration of distributed real-time and non-real-time systems.We test our proposed architecture using a distributed Command,Control,Communications,Computers,and Intelligence(C4I)system.The system has DDS-based real-time Combat Management System components deployed to naval warships,and SOA-based non-real-time Command and Control components used at headquarters.The proposed solution enables the exchange of data between these two systems efficiently.We compare the proposed solution with a similar study.Our solution is superior in terms of automation support,ease of implementation,scalability,and performance.
基金Supported by Beijing Traditional Chinese Medicine Scientific and Technological Development Fund Project,No.BJZYYB-2023-66Beijing Natural Science Foundation,No.7212050the Capital’s Funds for Health Improvement and Research,No.2020-4-2126.
文摘Schizophrenia is characterized by psychotic symptoms,negative symptoms,and cognitive deficits,profoundly affecting individuals and their families.The etiology is multifactorial,involving genetic,endocrine,and immunological risk factors.It is thought that schizophrenia is exclusively linked to alterations in brain structure and function,while the relationship between the brain and many organs may lack sufficient attention.Increasing evidence indicates abnormalities of the interactions between the brain and many organs in patients with schizophrenia.Inter-organ crosstalk affects the onset,course,and management of schizophrenia.Besides,the complex relationship between autonomic nervous system,endocrine system,and immune system further facilitates the development of schizophrenia.The present review summarizes the relationships between the brain and multiple organ systems in schizophrenia,providing new perspectives on the underlying pathophysiological mechanisms of schizophrenia.
基金supported by the National Natural Science Foundation of China(Grant No.82270892)Natural Science Foundation of Hubei Province(Grant No.2022CFB287)+2 种基金Xianning City Science and Technology Plan Project(Grant No.2022ZRKX052)School projects of Hubei University of Science and Technology(Grant No.2022T01,2021WG05,2021TNB01)Hubei University of Science and Technology School-level Fund(Grant No.BK202122).
文摘Background:Diabetic cardiomyopathy(DCM)is a type of cardiomyopathy caused by long-term diabetes,characterized by abnormal myocardial structure and function,which can lead to heart failure.Berberine(BBR),a quaternary ammonium alkaloid isolated from Coptidis Rhizoma,a traditional Chinese medicine,has superior anti-diabetic and heart-protective properties.The purpose of this study is to assess the impact of BBR on DCM.Methods:This study used a systems pharmacology approach to evaluate the related proteins and signalling pathways between BBR and DCM targets,combined with experimental validation using diabetic mouse heart sections.Microstructural and pathological changes were observed using Hematoxylin-eosin,Masson’s trichrome stain and wheat germ agglutinin staining.Immunofluorescence and western blot were used to determine protein expression.Results:The results indicate that BBR and DCM share 21 core relevant targets,with cross-targets predominantly located in mitochondrial,endoplasmic reticulum,and plasma membrane components.BBR exerts its main effects in improving DCM by maintaining mitochondrial integrity,particularly involving the PI3K-AKT-GSK3βand apoptosis signalling pathways.In addition,post-treatment changes in the key targets of BBR,including cysteine aspartate specific protease(Caspase)-3,phosphoinositide 3-kinase(PI3K)and mitochondria-related proteins,are suggestive of its efficacy.Conclusion:BBR crucially improves DCM by maintaining mitochondrial integrity,inhibiting apoptosis,and modulating PI3K-AKT-GSK3βsignaling.Further studies must address animal model limitations and validate clinical efficacy to understand BBR’s mechanisms fully and its potential clinical use.
文摘This study presents a(2+1)-dimensional complex coupled dispersionless system.A Lax pair is proposed,and the Darboux transformation is employed to construct multisoliton solutions.These solutions exhibit a range of wave phenomena,including bright and dark solitons,S-shaped formations,parabolic profiles,and periodic wave patterns.Additionally,it is shown that the system is equivalent to the sine-Gordon equation and the negative flow of the modified Korteweg-de Vries hierarchy through appropriate transformations.
基金funded by the Science and Technology Project of State Grid Shanxi Electric Power Company(5205E0230001).
文摘With the development of integrated power and gas distribution systems(IPGS)incorporating renewable energy sources(RESs),coordinating the restoration processes of the power distribution system(PS)and the gas distribution system(GS)by utilizing the benefits of RESs enhances service restoration.In this context,this paper proposes a coordinated service restoration framework that considers the uncertainty in RESs and the bi-directional restoration interactions between the PS and GS.Additionally,a coordinated service restoration model is developed considering the two systems’interdependency and the GS’s dynamic characteristics.The objective is to maximize the system resilience index while adhering to operational,dynamic,restoration logic,and interdependency constraints.A method for managing uncertainties in RES output is employed,and convexification techniques are applied to address the nonlinear constraints arising from the physical laws of the IPGS,thereby reducing solution complexity.As a result,the service restoration optimization problem of the IPGS can be formulated as a computationally tractable mixed-integer second-order cone programming problem.The effectiveness and superiority of the proposed framework are demonstrated through numerical simulations conducted on the interdependent IEEE 13-bus PS and 9-node GS.The comparative results show that the proposed framework improves the system resilience index by at least 65.07%compared to traditional methods.
基金supported by National Natural Science Foundation of China(52477101)Natural Science Foundation of Jiangsu Province(BK20210932).
文摘With the intensification of the energy crisis and the worsening greenhouse effect,the development of sustainable integrated energy systems(IES)has become a crucial direction for energy transition.In this context,this paper proposes a low-carbon economic dispatch strategy under the green hydrogen certificate trading(GHCT)and the ladder-type carbon emission trading(CET)mechanism,enabling the coordinated utilization of green and blue hydrogen.Specifically,a proton exchange membrane electrolyzer(PEME)model that accounts for dynamic efficiency characteristics,and a steam methane reforming(SMR)model incorporating waste heat recovery,are developed.Based on these models,a hydrogen production–storage–utilization framework is established to enable the coordinated deployment of green and blue hydrogen.Furthermore,the gas turbine(GT)unit are retrofitted using oxygenenriched combustion carbon capture(OCC)technology,wherein the oxygen produced by PEME is employed to create an oxygen-enriched combustion environment.This approach reduces energy waste and facilitates low-carbon power generation.In addition,the GHCT mechanism is integrated into the system alongside the ladder-type CET mechanism,and their complementary effects are investigated.A comprehensive optimization model is then formulated to simultaneously achieve carbon reduction and economic efficiency across the system.Case study results show that the proposed strategy reduces wind curtailment by 7.77%,carbon emissions by 65.98%,and total cost by 12.57%.This study offers theoretical reference for the low-carbon,economic,and efficient operation of future energy systems.
文摘To address the issues of unclear carbon responsibility attribution,insufficient renewable energy absorption,and simplistic carbon trading mechanisms in integrated energy systems,this paper proposes an electricheat-hydrogen integrated energy system(EHH-IES)optimal scheduling model considering carbon emission stream(CES)and wind-solar accommodation.First,the CES theory is introduced to quantify the carbon emission intensity of each energy conversion device and transmission branch by defining carbon emission rate,branch carbon intensity,and node carbon potential,realizing accurate tracking of carbon flow in the process of multi-energy coupling.Second,a stepped carbon pricing mechanism is established to dynamically adjust carbon trading costs based on the deviation between actual carbon emissions and initial quotas,strengthening the emission reduction incentive.Finally,a lowcarbon economic dispatch model is constructed with the objectives of minimizing operation cost,carbon trading cost,wind-solar curtailment penalty cost,and energy loss.Simulation results show that compared with the traditional economic dispatch scheme 3,the proposed schemel reduces carbon emissions by 53.97%and wind-solar curtailment by 68.89%with a 16.10%increase in total cost.This verifies that the model can effectively improve clean energy utilization and reduce carbon emissions,achieving low-carbon economic operation of EHH-IES,with CES theory ensuring precise carbon flow tracking across multi-energy links.
基金supported by the National Natural Science Foundation of China(Grant No.62471289)the Natural Science Foundation of Shanghai (Grant No.24ZR1432900)+1 种基金the Innovation Program for Quantum Science and Technology (Grant No.2021ZD0300703)Shanghai Municipal Science and Technology Major Project (Grant No.2019SHZDZX01)。
文摘Reliable detection of weak phase signals under significant channel loss and complex noise environments is a crucial step for practical applications of optical integrated communication and sensing systems. In this letter, we propose and experimentally demonstrate an enhanced long-distance weak signal transmission method assisted by weak measurement. Performing heterodyne detection and light intensity compensation on two nearly symmetric post-selected paths, the method enables real-time estimation of a time-varying phase while maintaining robustness against technical noises proportional to light intensity or photon number, detector common-mode noise, and significant attenuation over long-distance transmission. Experimental results indicate a potential phase sensitivity at the level of 10-8rad even with a signal light intensity attenuation of 48.1 d B. Potentially, combining the adaptive adjustment strategy, the method may provide a viable solution in remote weak signal detection and extraction,thereby contributing to optical integrated communication and sensing.
基金supported by National Natural Science Foundation of China(No.51902340)Chongqing Natural Science Foundation,and Chongqing Postdoctoral Science Foundation(No.2021000051).
文摘It is of great significance to develop clean and new energy sources with high-efficient energy storage technologies,due to the excessive use of fossil energy that has caused severe environmental damage.There is great interest in exploring advanced rechargeable lithium batteries with desirable energy and power capabilities for applications in portable electronics,smart grids,and electric vehicles.In practice,high-capacity and low-cost electrode materials play an important role in sustaining the progresses in lithium-ion batteries.This review aims at giving an account of recent advances on the emerging high-capacity electrode materials and summarizing key barriers and corresponding strategies for the practical viability of these electrode materials.Effective approaches to enhance energy density of lithium-ion batteries are to increase the capacity of electrode materials and the output operation voltage.On account of major bottlenecks of the power lithium-ion battery,authors come up with the concept of integrated battery systems,which will be a promising future for high-energy lithium-ion batteries to improve energy density and alleviate anxiety of electric vehicles.
基金co-supported by the National Natural Science Foundation of China(No.62073264)the Key Research and Development Project of Shaanxi Province,China(No.2021ZDLGY01-01 and 2020ZDLGY06-02)+2 种基金National Natural Science Foundation of China(No.61803309)China Postdoctoral Science Foundation(No.2018M633574)the Aeronautical Science Foundation of China(No.2019ZA053008)。
文摘In the missile-borne Strapdown Inertial Navigation System/Global Navigation Satellite System(SINS/GNSS)integrated navigation system,due to the factors such as the high dynamics,the signal blocking by obstacles,the signal intefereces,etc.,there always exist pulse interferences or measurement information interruptions in the satellite receiver,which make nonstationary measurement process.The traditional Kalman Filter(KF)can tackle the state estimation problem under Gaussian white noise,but its performance will be significantly reduced under nonGaussian noises.In order to deal with the non-Gaussian conditions in the actual missile-borne SINS/GNSS integrated navigation systems,a Maximum Versoria Criterion Extended Kalman Filter(MVC-EKF)algorithm is proposed based on the MVC and the idea of M-estimation,which assigns a smaller weight to the anomalous measurements so as to suppress the influence of anomalous measurements on the state estimation while maintaining a relatively low calculation cost.Finally,the integrated navigation simulation experiments prove the effectiveness and robustness of the proposed algorithm.
基金supported by NSF Grant DMS-0604638Li partially supported by NSF Grant DMS-0401174
文摘We classify all positive solutions for the following integral system：{ui（x）=∫Rn1/│x-y│^n-α fi（u（y））dy,x∈R^n,i=1,…,m,0〈α〈n,and u（x）=（u1（x）,u2（x）…,um（x））.Here fi（u）, 1 ≤ i ≤m, monotone nondecreasing are real-valued functions of homogeneous degree n＋α/n-α and are monotone nondecreasing with respect to all the independent variables U1, u2, ..., urn.In the special case n ≥ 3 and α = 2. we show that the above system is equivalent to thefollowing elliptic PDE system：This system is closely related to the stationary SchrSdinger system with critical exponents for Bose-Einstein condensate
文摘In this paper, a distributed control scheme has been developed for consensus of single integrator multi-agent systems with directed fixed communication topology for arbitrarily large constant, time-varying or distributed communication delays. It is proved that the closed loop control system can reach consensus with an exponential convergence rate if and only if the topology is quasi-strongly connected. Simulation results are also provided to demonstrate the effectiveness of the proposed controller.
基金Project supported by the National Natural Science Foundation of China (Grant Nos.61072147 and 11071159)the Natural Science Foundation of Shanghai,China (Grant No.09ZR1410800)+2 种基金the Science Foundation of the Key Laboratory of Mathematics Mechanization,China (Grant No.KLMM0806)the Shanghai Leading Academic Discipline Project,China (Grant No.J50101)the Key Disciplines of Shanghai Municipality of China (Grant No.S30104)
文摘The symmetry constraint and binary nonlinearization of Lax pairs for the super classical-Boussinesq hierarchy is obtained. Under the obtained symmetry constraint, the n-th flow of the super classical-Boussinesq hierarchy is decomposed into two super finite-dimensional integrable Hamiltonian systems, defined over the super-symmetry manifold with the corresponding dynamical variables x and tn. The integrals of motion required for Liouville integrability are explicitly given.
基金Supported by the National Natural Science Foundation of China under Grant No 10371070.
文摘The Lax pair of the mixed Ablowitz-Kap-Newell-Segur （AKNS） system is obtained from compatibility condition. Hirota＇s bilinear form is derived by some dependent variable transformation. Moreover, by means of the Wronskian technique, the double Wronskian form of soliton solutions are found. Specially, the two-soliton solution is presented.
基金sponsored by the National Natural Science Foundations of China(No.11975131,11435005)K C Wong Magna Fund in Ningbo University。
文摘Multi-place nonlocal systems have attracted attention from many scientists.In this paper,we mainly review the recent progresses on two-place nonlocal systems(Alice-Bob systems)and four-place nonlocal models.Multi-place systems can firstly be derived from many physical problems by using a multiple scaling method with a discrete symmetry group including parity,time reversal,charge conjugates,rotations,field reversal and exchange transformations.Multiplace nonlocal systems can also be derived from the symmetry reductions of coupled nonlinear systems via discrete symmetry reductions.On the other hand,to solve multi-place nonlocal systems,one can use the symmetry-antisymmetry separation approach related to a suitable discrete symmetry group,such that the separated systems are coupled local ones.By using the separation method,all the known powerful methods used in local systems can be applied to nonlocal cases.In this review article,we take two-place and four-place nonlocal nonlinear Schr?dinger(NLS)systems and Kadomtsev-Petviashvili(KP)equations as simple examples to explain how to derive and solve them.Some types of novel physical and mathematical points related to the nonlocal systems are especially emphasized.
基金supported by National Key R&D Program of China(Grant No.2018 YFC0809400)Zhejiang Provincial Natural Science Foundation of China(Grant No.LY16A020001)National Natural Science Foundation of China(Grant No.11802267).
文摘The reliability of quasi integrable and non-resonant Hamiltonian system under fractional Gaussian noise(fGn)excitation is studied.Noting rather flat fGn power spectral density(PSD)in most part of frequency band,the fGn is innovatively regarded as a wide-band process.Then,the stochastic averaging method for quasi integrable Hamiltonian systems under wide-band noise excitation is applied to reduce 2n-dimensional original system into n-dimensional averaged ltd stochastic differential equations(SDEs).Reliability function and mean first passage time are obtained by solving the associated backward Kolmogorov equation and Pontryagin equation.The validity of the proposed procedure is tested by applying it to an example and comparing the numerical results with those from Monte Carlo simulation.
基金sponsored by the National Natural Science Foundation of China(Nos.12235007,11975131)。
文摘A new type of symmetry,ren-symmetry,describing anyon physics and corresponding topological physics,is proposed.Ren-symmetry is a generalization of super-symmetry which is widely applied in super-symmetric physics such as super-symmetric quantum mechanics,super-symmetric gravity,super-symmetric string theory,super-symmetric integrable systems and so on.Supersymmetry and Grassmann numbers are,in some sense,dual conceptions,and it turns out that these conceptions coincide for the ren situation,that is,a similar conception of ren-number(R-number)is devised for ren-symmetry.In particular,some basic results of the R-number and ren-symmetry are exposed which allow one to derive,in principle,some new types of integrable systems including ren-integrable models and ren-symmetric integrable systems.Training examples of ren-integrable KdV-type systems and ren-symmetric KdV equations are explicitly given.
