Breast cancer is the most prevalent form of cancer among women,with a staggering 2.3 million new cases and 680,000deaths reported annually in recent years.The high mortality rate is primarily attributed to metastasis,...Breast cancer is the most prevalent form of cancer among women,with a staggering 2.3 million new cases and 680,000deaths reported annually in recent years.The high mortality rate is primarily attributed to metastasis,as most fatalities arise from secondary growths in organs such as the bone,liver,lung,and brain rather than the primary tumor[1].Cancer cells possess invasive migratory capabilities that enable them to spread to secondary organs via the bloodstream or lymphatic system.Effective treatment strategies prioritize understanding the entire tumor ecosystem to holistically address the complexity of this disease[2].展开更多
基金supported by the National Natural Science Foundation of China(12325405 and 22307098)the National Key Research and Development Program of China(2022YFA1405002)the Strategic Priority Research Program of Chinese Academy of Sciences(XDB33000000)。
文摘Breast cancer is the most prevalent form of cancer among women,with a staggering 2.3 million new cases and 680,000deaths reported annually in recent years.The high mortality rate is primarily attributed to metastasis,as most fatalities arise from secondary growths in organs such as the bone,liver,lung,and brain rather than the primary tumor[1].Cancer cells possess invasive migratory capabilities that enable them to spread to secondary organs via the bloodstream or lymphatic system.Effective treatment strategies prioritize understanding the entire tumor ecosystem to holistically address the complexity of this disease[2].
